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2024

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The Influence Of Teaching Digital Resources Of Myplate On Nutrition Knowledge, Attitudes, And Practice (Kap) For Healthy Eating Habits Of Children, Afaf Alsofyani Aug 2024

The Influence Of Teaching Digital Resources Of Myplate On Nutrition Knowledge, Attitudes, And Practice (Kap) For Healthy Eating Habits Of Children, Afaf Alsofyani

Electronic Theses and Dissertations

This study examines the influence of teaching digital resources of MyPlate on the nutrition knowledge, attitudes, and practices (KAP) related to healthy eating habits among first and second-grade students. A pre-and post-assessment of this quasi-experimental research study measured the baseline KAP levels of 45 participants regarding healthy eating habits. Students were divided into three groups: digital MyPlate (n =16), pencil-and-paper (n =15), and control (n =14). Following the pre-assessment, an intervention was conducted involving teaching MyPlate and the five food groups. A post-assessment was then implemented to measure the change in KAP levels resulting from the intervention. …


Trauma Informed Schools: Investigating K-12 Educator Perceptions From Professional Learning To Implementing Practices, Kelsey Cupp Aug 2024

Trauma Informed Schools: Investigating K-12 Educator Perceptions From Professional Learning To Implementing Practices, Kelsey Cupp

Electronic Theses and Dissertations

The purpose of this quantitative study was to further the understanding on how access to trauma-informed professional learning changed research-based practices in classroom and school-wide settings in K-12 schools. The guiding question for this quantitative study was: How has trauma-informed professional learning influenced changes in research-based practices in school-wide and classroom settings in K-12 schools? This research assessed the perceptions of elementary, middle, and high school teachers in one school district to investigate access to trauma-informed professional learning and potential changes in research-based practices in school-wide and classroom settings. Participants were teachers, in Northeast Tennessee, employed in urban schools implementing …


Insulin Resistance In Women Correlates With Chromatin Histone Lysine Acetylation, Inflammatory Signaling, And Accelerated Aging, Christina Vidal, Jackelyn Alva-Ornelas, Nancy Zhuo Chen, Parijat Senapati, Jerneja Tomsic, Vanessa Myriam Robles, Cristal Resto, Nancy Sanchez, Angelica Sanchez, Terry Hyslop, Nour Emwas, Dana Aljaber, Nick Bachelder, Ernest Martinez, David Ann, Veronica Jones, Robert Winn, Lucio Miele, Augusto Ochoa, Eric Dietze, Rama Natarajan, Dustin Schones, Victoria Seewaldt Aug 2024

Insulin Resistance In Women Correlates With Chromatin Histone Lysine Acetylation, Inflammatory Signaling, And Accelerated Aging, Christina Vidal, Jackelyn Alva-Ornelas, Nancy Zhuo Chen, Parijat Senapati, Jerneja Tomsic, Vanessa Myriam Robles, Cristal Resto, Nancy Sanchez, Angelica Sanchez, Terry Hyslop, Nour Emwas, Dana Aljaber, Nick Bachelder, Ernest Martinez, David Ann, Veronica Jones, Robert Winn, Lucio Miele, Augusto Ochoa, Eric Dietze, Rama Natarajan, Dustin Schones, Victoria Seewaldt

Kimmel Cancer Center Faculty Papers

BACKGROUND: Epigenetic changes link medical, social, and environmental factors with cardiovascular and kidney disease and, more recently, with cancer. The mechanistic link between metabolic health and epigenetic changes is only starting to be investigated. In our in vitro and in vivo studies, we performed a broad analysis of the link between hyperinsulinemia and chromatin acetylation; our top "hit" was chromatin opening at H3K9ac.

METHODS: Building on our published preclinical studies, here, we performed a detailed analysis of the link between insulin resistance, chromatin acetylation, and inflammation using an initial test set of 28 women and validation sets of 245, 22, …


Peripheral Vascular Function In Young Adults With Increased Risk Of Cardiometabolic Disease, Ryan S. Aultman Aug 2024

Peripheral Vascular Function In Young Adults With Increased Risk Of Cardiometabolic Disease, Ryan S. Aultman

Master's Theses

Objective: To determine if young adults with elevated metabolic syndrome severity scores (MetSindex) suffer from peripheral vasculature dysfunction.

Methods: Mean arterial pressure (MAP), Femoral (FBF) and Brachial Blood flow (BBF), Femoral (FVC) and Brachial Vascular Conductance (BVC), and Tissue Saturation Index (TSI) were assessed in twenty-four age (19 + 2.25 years), Sex (male: n=18; female: n=6) and Race (White: n=4; Black/African American: n=4; Asian: n=16) matched individuals during post-occlusive reactive hyperemia (RHBF), passive limb movement (PLM) and Functional Sympatholysis (FS) trials. Carotid femoral pulse wave velocity (cfPWV) was also collected at baseline, and all values were compared between …


Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama Aug 2024

Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama

Master's Theses

Previous research has shown that increasing cycling cadence, rather than the workrate, can result in improved post-cycling gait velocity. However, the specific threshold of cycling cadence required to bring about clinically meaningful changes in gait velocity remains unknown. To address this knowledge gap, our study aimed to determine the minimum incremental increase in cycling cadence that would lead to a significant improvement in post-cycling gait velocity. A total of 42 young adults participated in our study and were randomly assigned to one of three groups: TEN, TWENTY, and THIRTY. Each group was assigned to cycle at a cadence at the …


Assessments Of Thickeners For Home Cooked Pureed Diets Meals For Patients With Dysphagia On Pureed Diets, Amy Rosales Aug 2024

Assessments Of Thickeners For Home Cooked Pureed Diets Meals For Patients With Dysphagia On Pureed Diets, Amy Rosales

Electronic Theses, Projects, and Dissertations

Managing dysphagia can help prevent adverse outcomes for patients with swallowing issues. This project aims to identify the best thickener that holds food texture and to identify which thickener is most palatable and acceptable by evaluators. A Spoon Tilt test was used to as one of the objective tests to determine the best thickener that holds food texture. The three thickening agents used were: apple pectin powder, tapioca starch, and a commercial thickener. The three pureed food items used to test the thickening agents were baked chicken, broccoli, and rice. An audit tool by the International Dysphagia Diet Standardization Initiative …


N Y State Dent J August-September 2024 Aug 2024

N Y State Dent J August-September 2024

The New York State Dental Journal

In the August-September 2024 issue, the reader will find the following feature articles:

  • Success of Implant Placement in Patients with Human Immunodeficiency Virus
  • Effects of Mandatory COVID-19 Testing Policy on No-Show Rates for Aerosol-Generating Procedures
  • Heterotopic Bone Formation after TMJ Surgery
  • Rural Oral Health Access Disparities in New York State

This issue includes regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.


Psychological Science And Immigration Today: Apa Task Force Report On Immigration And Health, American Psychological Association, Alfonso Mercado, Amanda Venta, Dina Birman, German Cadenas, Gail Ferguson, Luz M. Garcini, Giselle A. Hass, Maryam Kia-Keating, William Martinez Aug 2024

Psychological Science And Immigration Today: Apa Task Force Report On Immigration And Health, American Psychological Association, Alfonso Mercado, Amanda Venta, Dina Birman, German Cadenas, Gail Ferguson, Luz M. Garcini, Giselle A. Hass, Maryam Kia-Keating, William Martinez

Psychological Science Faculty Publications

The report emphasizes the importance of culturally competent mental health services and explores the impact of anti-immigration policies on mental wellbeing. In today’s climate in which immigration is often met with hostility, it is crucial that we, as researchers and mental health professionals, understand the unique challenges faced by immigrants and use this understanding to foster positive change. Together, we can better support the wellbeing and resilience of our immigrant communities by using psychological research to inform and advance practice and policy.


Individually Randomized Trial Mislabeled As A Cluster-Randomized Trial Comment On: “Effectiveness Of Wearable Technology To Optimize Youth Soccer Players’ Off-Training Behaviour And Training Responses: A Cluster-Randomized Trial”, Jean Michel R S Leite, Jasmine Jamshidi-Naeini, Colby J Vorland, Lilian Golzarri-Arroyo, David B Allison Aug 2024

Individually Randomized Trial Mislabeled As A Cluster-Randomized Trial Comment On: “Effectiveness Of Wearable Technology To Optimize Youth Soccer Players’ Off-Training Behaviour And Training Responses: A Cluster-Randomized Trial”, Jean Michel R S Leite, Jasmine Jamshidi-Naeini, Colby J Vorland, Lilian Golzarri-Arroyo, David B Allison

Children’s Nutrition Research Center Staff Publications

No abstract provided.


Eating Disorders And Oral Health: A Dental Professional's Role, Bree Zhang Aug 2024

Eating Disorders And Oral Health: A Dental Professional's Role, Bree Zhang

The New York State Dental Journal

Eating disorders are more common than we think, affecting 9% of the world's population and increasing in prevalence each year. Research shows early intervention provides a greater chance of recovery. Dentists must be cognizant of signs their patients may be engaged in harmful eating behavior and be prepared to intervene.


A New Hope: Contextual Privacy Policies For Mobile Applications And An Approach Toward Automated Generation, Shidong Pan, Zhen Tao, Thong Hoang, Dawen Zhang, Tianshi Li, Zhenchang Xing, Xiwei Xu, Mark Staples, Thierry Rakotoarivelo, David Lo Aug 2024

A New Hope: Contextual Privacy Policies For Mobile Applications And An Approach Toward Automated Generation, Shidong Pan, Zhen Tao, Thong Hoang, Dawen Zhang, Tianshi Li, Zhenchang Xing, Xiwei Xu, Mark Staples, Thierry Rakotoarivelo, David Lo

Research Collection School Of Computing and Information Systems

Privacy policies have emerged as the predominant approach to conveying privacy notices to mobile application users. In an effort to enhance both readability and user engagement, the concept of contextual privacy policies (CPPs) has been proposed by researchers. The aim of CPPs is to fragment privacy policies into concise snippets, displaying them only within the corresponding contexts within the application’s graphical user interfaces (GUIs). In this paper, we first formulate CPP in mobile application scenario, and then present a novel multimodal framework, named SEEPRIVACY, specifically designed to automatically generate CPPs for mobile applications. This method uniquely integrates vision-based GUI understanding …


August 2024 News Releases, University Of Montana--Missoula. Office Of University Relations Aug 2024

August 2024 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.


Trends In Central Nervous System-Active Polypharmacy Among People With Multiple Sclerosis, Hayden Naizer, Joseph Wozny, Trudy Millard Krause, Ethan Huson, Leorah Freeman Aug 2024

Trends In Central Nervous System-Active Polypharmacy Among People With Multiple Sclerosis, Hayden Naizer, Joseph Wozny, Trudy Millard Krause, Ethan Huson, Leorah Freeman

Faculty, Staff and Student Publications

BACKGROUND: People with multiple sclerosis (pwMS) are at risk of concurrently using multiple central nervous system (CNS)-active drugs, yet the prevalence of CNS-active polypharmacy remains unmeasured in pwMS.

OBJECTIVE: The objective is to measure the prevalence of CNS-active polypharmacy in pwMS.

METHODS: This serial, cross-sectional study measured CNS-active polypharmacy in people with MS in the United States from 2008 to 2021 using insurance claims data. CNS-active polypharmacy was defined as the concurrent prescription of ⩾3 CNS-active drugs for >30 continuous days. CNS-active drugs included antidepressants, antiepileptics, antipsychotics, benzodiazepines, nonbenzodiazepine benzodiazepine receptor agonist hypnotics, opioids, and skeletal muscle relaxants.

RESULTS: The …


Plasma Proteins Associated With Plant-Based Diets: Results From The Atherosclerosis Risk In Communities (Aric) Study And Framingham Heart Study (Fhs), Hyunju Kim, Jingsha Chen, Brenton Prescott, Maura E Walker, Morgan E Grams, Bing Yu, Ramachandran S Vasan, James S Floyd, Nona Sotoodehnia, Nicholas L Smith, Dan E Arking, Josef Coresh, Casey M Rebholz Aug 2024

Plasma Proteins Associated With Plant-Based Diets: Results From The Atherosclerosis Risk In Communities (Aric) Study And Framingham Heart Study (Fhs), Hyunju Kim, Jingsha Chen, Brenton Prescott, Maura E Walker, Morgan E Grams, Bing Yu, Ramachandran S Vasan, James S Floyd, Nona Sotoodehnia, Nicholas L Smith, Dan E Arking, Josef Coresh, Casey M Rebholz

Faculty, Staff and Student Publications

Background & aims: Plant-based diets are associated with a lower risk of chronic diseases. Large-scale proteomics can identify objective biomarkers of plant-based diets, and improve our understanding of the pathways that link plant-based diets to health outcomes. This study investigated the plasma proteome of four different plant-based diets [overall plant-based diet (PDI), provegetarian diet, healthful plant-based diet (hPDI), and unhealthful plant-based diet (uPDI)] in the Atherosclerosis Risk in Communities (ARIC) Study and replicated the findings in the Framingham Heart Study (FHS) Offspring cohort.

Methods: ARIC Study participants at visit 3 (1993-1995) with completed food frequency questionnaire (FFQ) data and proteomics …


Don't Waste Our Time: Key Transformative Structures For Fast Track Learning, Carlita S. King Aug 2024

Don't Waste Our Time: Key Transformative Structures For Fast Track Learning, Carlita S. King

All Dissertations

Following a massive wave of school closures during the COVID-19 pandemic, educators found the need to be hyper-critical of how they spend their instructional time with students. Almost all students are expected to return nearly a full grade-level behind and would likely have to learn to navigate a completely new school environment. As a result, many educators were overwhelmed to cover unprecedented amounts of instructional content in less time. High-intensity tutoring programs have been known to have the potential to help struggling students advance their skills and gain up to three additional months of learning within a few sessions. The …


Effect Of Long-Term Use Of Antimicrobials On Commonly Used Surfaces In Foodservice Establishments, Anuradhi Bandaranayake Aug 2024

Effect Of Long-Term Use Of Antimicrobials On Commonly Used Surfaces In Foodservice Establishments, Anuradhi Bandaranayake

All Dissertations

none


Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha Aug 2024

Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha

All Dissertations

ABSTRACT

This study explored the mental health of healthcare practitioners in Kosovo during the COVID-19 pandemic, focusing on the prevalence of stress, depression, and anxiety, and the associated individual, family, and work-related factors. The research employed a cross-sectional design with a sample of 449 healthcare workers from two hospitals in Kosovo. The Depression, Anxiety, and Stress Scale (DASS-21) was used to assess mental health symptoms, while socio-demographic and work-related information was collected through a questionnaire.

Based on the descriptive statistics of DASS-21 scores, the prevalence of mental health issues among the participants included high levels of depression (18%), anxiety (25%), …


Ensuring The Privacy Compliance Of Voice Personal Assistant Applications, Song Liao Aug 2024

Ensuring The Privacy Compliance Of Voice Personal Assistant Applications, Song Liao

All Dissertations

Voice Personal Assistants (VPA) such as Amazon Alexa and Google Assistant are quickly and seamlessly integrating into people’s daily lives. Meanwhile, the increased reliance on VPA services raises privacy concerns, such as the leakage of private conversations and sensitive information. Privacy policies play an important role in addressing users’ privacy concerns and developers are required to provide privacy policies to disclose their apps’ data practices. In addition, voice apps targeting users in European countries are required to comply with the GDPR (General Data Protection Regulation). However, little is known about whether these privacy policies are informative and trustworthy on emerging …


Consumer Perceptions Of Hemp-Fed Aquaculture, Jillian Hyink Aug 2024

Consumer Perceptions Of Hemp-Fed Aquaculture, Jillian Hyink

Graduate Theses and Dissertations

Global demand for seafood has increased significantly over the past several decades and is projected to continue rising in the future. The volume of aquaculture production has also particularly increased to meet this demand in the United States and globally, offering a relatively sustainable supplement to wild fish supplies. However, conventional fish farming uses unsustainable quantities of fishmeal and fish oil as feed inputs, which raises the cost of production and introduces safety concerns associated with fish consumption. One currently underexplored potential alternative to fishmeal is hemp grain, which can provide an affordable and nutritious feed for carnivorous fish and …


The Impact Of Reactive Oxygen Species On Bactericidal Activity And Drug Resistance In Salmonella Typhimurium Upon Chlorine And Eugenol Exposure, Mohammed Aljuwayd Aug 2024

The Impact Of Reactive Oxygen Species On Bactericidal Activity And Drug Resistance In Salmonella Typhimurium Upon Chlorine And Eugenol Exposure, Mohammed Aljuwayd

Graduate Theses and Dissertations

Salmonella Typhimurium (S.T) is a foodborne pathogenic bacterium which causes salmonellosis in human beings. Chicken is the most common source of S.T contamination. In chapter I, I discuss the growth of the poultry industry, the role chickens play as Salmonella reservoirs, the spread of drug-resistant strains caused by chicken husbandry and antibiotic use, and how eugenol can be used in poultry feed to decrease Salmonella infections and improve intestinal health. In chapter Ⅱ, I summarize the role of reactive oxygen species (ROS) in bactericidal activity. In chapter Ⅲ, I describe the killing mechanism of sodium hypochlorite (NaOCl) and identify the …


Facilitating Parental Scaffolding Of Joint Book Reading With Toddlers, Tiffany Pempek Rahl Aug 2024

Facilitating Parental Scaffolding Of Joint Book Reading With Toddlers, Tiffany Pempek Rahl

Dissertations, 2020-current

Developmental research confirms the importance of early parental language input for building children’s vocabulary and language skills (Hart & Risley, 1995). While reading with a caregiver is a common way for language input to occur, the approaches parents utilize often fail to capitalize on techniques for improving language and pre-literacy skills (Huebner & Meltzoff, 2005). The purpose of this study was to assess the effectiveness of embedding tips for scaffolding parent reading strategies into a children’s book. Thirty-eight parent-child dyads participated in a 2-week intervention. Families were randomly assigned to receive either a book with embedded tips (experimental condition) or …


Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka Aug 2024

Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka

General Surgery, East Africa

Importance: Effective communication between patients and health care teams is essential in the health care setting for delivering optimal cancer care and increasing cancer awareness. While the significance of communication in health care is widely acknowledged, the topic is largely understudied within African settings.

Objective: To assess how the medical language of cancer and oncology translates into African languages and what these translations mean within their cultural context.

Design, etting, and participants: In this multinational survey study in Africa, health professionals, community health workers, researchers, and scientists involved in cancer care and research and traditional healers were invited to participate …


Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu Aug 2024

Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu

Haematology and Oncology, East Africa

In 2018, there were an estimated 18 million cancer cases worldwide, with lymphoma, multiple myeloma, and leukemia contributing to a significant portion of these cases. Lymphoma accounted for 79,990 cases, multiple myeloma for 159,985 cases, and leukemia for 437,033 cases globally (AICR, 2018). In the United States alone, approximately 30,770 people are diagnosed with multiple myeloma each year. Multiple myeloma comprises about 1.8% of all cancers and around 10% of all “blood cancers,” which includes leukemia (Penn Medicine, 2020). India ranks third in the highest reported cases of blood cancer, following the United States and China, affecting more than 70,000 …


Validation Of Scores From A Telephone Administered Multiple Sclerosis Walking Scale-12 In Persons With Multiple Sclerosis, Robert W. Motl, Prudence Plummer, Deborah Backus, Jeffrey R. Hebert, Whitney N. Neal, Alexander V. Ng, John Lowman, Francois Bethoux, Hollie Schmidt, Robert Mcburney, Kevin K. Mccully, Gary R. Cutter Aug 2024

Validation Of Scores From A Telephone Administered Multiple Sclerosis Walking Scale-12 In Persons With Multiple Sclerosis, Robert W. Motl, Prudence Plummer, Deborah Backus, Jeffrey R. Hebert, Whitney N. Neal, Alexander V. Ng, John Lowman, Francois Bethoux, Hollie Schmidt, Robert Mcburney, Kevin K. Mccully, Gary R. Cutter

Exercise Science Faculty Research and Publications

Background

The Multiple Sclerosis Walking Scale-12 (MSWS-12) has typically been delivered through paper-and-pencil or computer-based administration.

Purpose

This study examined the validity of inferences from scores derived via a telephone administration of the MSWS-12 applied as part of screening of participants with walking dysfunction into a clinical trial of exercise training in MS.

Method

The MSWS-12 was administered on two occasions separated by approximately 2 weeks through the telephone and then in-person (i.e., computer-based administration). Participants further completed the Patient Determined Disease Steps (PDDS) scale, timed 25-foot walk (T25FW), six-minute walk (6MW), Modified Fatigue Impact Scale (MFIS), and Multiple Sclerosis …


Genotype-By-Environment Interactions In Nonalcoholic Fatty Liver Disease And Chronic Illness Among Mexican Americans: The Role Of Acculturation Stress, Eron Manusov, Vincent Diego, Marcio Almeida, David Ortiz, Joanne E. Curran, Jacob Galan, Ana C. Leandro, Sandra Laston, John Blangero, Sarah Williams-Blangero Aug 2024

Genotype-By-Environment Interactions In Nonalcoholic Fatty Liver Disease And Chronic Illness Among Mexican Americans: The Role Of Acculturation Stress, Eron Manusov, Vincent Diego, Marcio Almeida, David Ortiz, Joanne E. Curran, Jacob Galan, Ana C. Leandro, Sandra Laston, John Blangero, Sarah Williams-Blangero

School of Medicine Publications

This study examines the complex interplay of genetic and environmental interactions that shape chronic illness risk. Evidence is mounting for the role of genetic expression and the immune response in the pathogenesis of chronic disease. In the Rio Grande Valley of south Texas, where 90% of the population is Mexican American, chronic illnesses (including obesity, diabetes, nonalcoholic liver disease, and depression) are reaching epidemic proportions. This study leverages an ongoing family study of the genetic determinants of risk for obesity, diabetes, hypertension, hyperlipidemia, and depression in a Mexican American population. Data collected included blood pressure, BMI, hepatic transaminases, HbA1c, depression …


Milk Exosome-Glow Nanosystem For Cancer Cellular And Tissue Bioimaging, Nycol Cotto, Neeraj Chauhan, Benilde Adriano, Deepak S. Chauhan, Marco A. Cabrera, Subhash Chauhan, Murali Yallapu Aug 2024

Milk Exosome-Glow Nanosystem For Cancer Cellular And Tissue Bioimaging, Nycol Cotto, Neeraj Chauhan, Benilde Adriano, Deepak S. Chauhan, Marco A. Cabrera, Subhash Chauhan, Murali Yallapu

School of Medicine Publications

Milk-derived exosomes are widely used for diagnosis, delivery, imaging, and theranostic applications. Near-Infrared (NIR) based fluorescence bioimaging is an attractive and safer technique that is used for clinical applications. However, almost all NIR imaging agents tend to have poor photostability, short half-life, nonspecific protein binding, and concentration-dependent aggregation(s). Therefore, there is an unmet clinical need to develop newer and safer modalities to package and deliver NIR imaging agents. Bovine milk exosomes are natural, biocompatible, safe, and efficient nanocarriers that facilitate the delivery of micro- and macromolecules. Herein, we developed an exosome-based NIR dye loaded nanoimaging formulation that offers improved solubility …


Blood, Sweat, And Tears: Implications For Hydration Testing In Combat Sports—Investigating Body Mass Loss And Biomarker Changes, Colin S. Doherty, Lauren V. Fortington, Oliver R. Barley Aug 2024

Blood, Sweat, And Tears: Implications For Hydration Testing In Combat Sports—Investigating Body Mass Loss And Biomarker Changes, Colin S. Doherty, Lauren V. Fortington, Oliver R. Barley

Research outputs 2022 to 2026

Combat sports athletes often undergo rapid body mass loss (BML), which presents health risks. Hydration testing has been proposed as a possible solution to reduce or eliminate rapid BML. However, combat sports athletes may exhibit distinct physiological characteristics due to repeated exposure to BML. Thus, traditional and emerging hydration biomarkers should be investigated to determine their potential suitability for field use in this cohort. This study examined whether BML can explain changes in serum and urine osmolality (SosmΔ, UosmΔ), tear osmolarity (TosmΔ), hematocrit (HctΔ), and urine-specific gravity (USGΔ) after mild–moderate passive dehydration. Biomarker reliability was also assessed across two trials. …


Apolipoprotein Ε4 Is Associated With Increased Risk Of Fall- And Fracture-Related Hospitalization: The Perth Longitudinal Study Of Ageing Women, Jedd Pratt, Jack Dalla Via, Craig Sale, Abadi K. Gebre, Blossom C.M. Stephan, Simon Laws, Kun Zhu, Wai H. Lim, Richard L. Prince, Joshua R. Lewis, Marc Sim Aug 2024

Apolipoprotein Ε4 Is Associated With Increased Risk Of Fall- And Fracture-Related Hospitalization: The Perth Longitudinal Study Of Ageing Women, Jedd Pratt, Jack Dalla Via, Craig Sale, Abadi K. Gebre, Blossom C.M. Stephan, Simon Laws, Kun Zhu, Wai H. Lim, Richard L. Prince, Joshua R. Lewis, Marc Sim

Research outputs 2022 to 2026

Apolipoprotein ε4 (APOE ε4) may be a genetic risk factor for reduced bone mineral density (BMD) and muscle function, which could have implications for fall and fracture risk. We examined the association between APOE ε4 status and long-term fall- and fracture-related hospitalization risk in older women. A total of 1 276 community-dwelling women from the Perth Longitudinal Study of Aging Women (mean age ± SD = 75.2 ± 2.7 years) were included. At baseline, women underwent APOE genotyping and detailed phenotyping for covariates including prevalent falls and fractures, as well as health and lifestyle factors. The association between APOE ε4 …


Assessing Sarcopenia In Advanced-Stage Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Case Series, Christelle Schofield, Dennis R. Taaffe, Robert U. Newton, Daniel A. Galvão, Paul A. Cohen, Jin Soo Kim, Tarek Meniawy, Carolyn Peddle-Mcintyre Aug 2024

Assessing Sarcopenia In Advanced-Stage Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Case Series, Christelle Schofield, Dennis R. Taaffe, Robert U. Newton, Daniel A. Galvão, Paul A. Cohen, Jin Soo Kim, Tarek Meniawy, Carolyn Peddle-Mcintyre

Research outputs 2022 to 2026

Objectives: In ovarian and other cancers, low muscle mass and density are associated with poorer clinical outcomes. However, screening for cancer-related sarcopenia (typically defined as low muscle mass) is not routinely conducted. The European Working Group on Sarcopenia in Older People (EWGSOP) recommends an algorithm for sarcopenia screening and diagnosis in clinical settings, with sarcopenia based on muscle strength and mass, and severity on physical performance. We explored the application of the EWGSOP2 algorithm to assess sarcopenia in six ovarian cancer patients receiving neoadjuvant chemotherapy. Methods: We assessed sarcopenia risk with the SARC-F screening questionnaire (at risk ≥4 points), muscle …


Fatigue Performance Of 3d-Printed Poly-Lactic-Acid Bone Scaffolds With Triply Periodic Minimal Surface And Voronoi Pore Structures, Hamed Bakhtiari, Alireza Nouri, Majid Tolouei-Rad Aug 2024

Fatigue Performance Of 3d-Printed Poly-Lactic-Acid Bone Scaffolds With Triply Periodic Minimal Surface And Voronoi Pore Structures, Hamed Bakhtiari, Alireza Nouri, Majid Tolouei-Rad

Research outputs 2022 to 2026

Bone scaffolds serve a crucial role in tissue engineering, particularly in facilitating bone regeneration where natural repair is insufficient. Despite advancements in the fabrication of polymeric bone scaffolds, the challenge remains to optimize their mechanical resilience. Specifically, research on the fatigue behaviour of polymeric bone scaffolds is scarce. This study investigates the influence of pore architecture on the mechanical performance of poly-lactic-acid (PLA) scaffolds under quasi-static and cyclic compression. PLA scaffolds with a 60% porosity were fabricated using extrusion-based 3D printing in various designs: Gyroid, Lidinoid, Fischer–Koch, IWP, and Voronoi. Results demonstrated that Gyroid scaffolds had the highest compressive strength …