Digital Commons Network^™

Effect Of Stocking Density On Growth, Biochemical Composition, And Blood Parameters In The Pacific Shortfin Eel (Anguilla Bicolor Pacifica) Elvers, Frolan A. Aya, John Carlo L. Unida, Luis Maria B. Garcia, Rowena R. Eguia Ma.

The Philippine Agricultural Scientist

This study examined the effect of stocking density on growth, biochemical composition, and blood parameters of the Pacific shortfin eel Anguilla bicolor pacifica. Elvers (1.95 ± 0.14 g body weight) were randomly stocked in indoor tanks and reared over 186 d at three stocking densities (0.3, 0.6, and 0.9 kg m^-3) set up in triplicates. Except for survival and biometric indices, elvers maintained at 0.3 and 0.6 kg m^-3 densities exhibited higher growth and feed utilization than those held at 0.9 kg m^-3. Yield increased with stocking density, which were significantly higher at 0.6 …

Diverse And Multifunctional Roles For Perlecan (Hspg2) In Repair Of The Intervertebral Disc, James Melrose, Farshid Guilak

2020-Current year OA Pubs

Perlecan is a widely distributed, modular, and multifunctional heparan sulfate proteoglycan, which facilitates cellular communication with the extracellular environment to promote tissue development, tissue homeostasis, and optimization of biomechanical tissue functions. Perlecan-mediated osmotic mechanotransduction serves to regulate the metabolic activity of cells in tissues subjected to tension, compression, or shear. Perlecan interacts with a vast array of extracellular matrix (ECM) proteins through which it stabilizes tissues and regulates the proliferation or differentiation of resident cell populations. Here we examine the roles of the HS-proteoglycan perlecan in the normal and destabilized intervertebral disc. The intervertebral disc cell has evolved to survive …

Distinct Basal Forebrain-Originated Neural Circuits Promote Homoeostatic Feeding And Suppress Hedonic Feeding In Male Mice, Hailan Liu, Jonathan C Bean, Yongxiang Li, Meng Yu, Olivia Z Ginnard, Kristine M Conde, Mengjie Wang, Xing Fang, Hesong Liu, Longlong Tu, Na Yin, Junying Han, Yongjie Yang, Qingchun Tong, Benjamin R Arenkiel, Chunmei Wang, Yang He, Yong Xu

Faculty, Staff and Students Publications

Feeding behaviour is influenced by two primary factors: homoeostatic needs driven by hunger and hedonic desires for pleasure even in the absence of hunger. While efficient homoeostatic feeding is vital for survival, excessive hedonic feeding can lead to adverse consequences such as obesity and metabolic dysregulations. However, the neurobiological mechanisms that orchestrate homoeostatic versus hedonic food consumption remain largely unknown. Here we show that GABAergic proenkephalin (Penk) neurons in the diagonal band of Broca (DBB) of male mice respond to food presentation. We further demonstrate that a subset of DBBPenk neurons that project to the paraventricular nucleus of the hypothalamus …

Measures Of Justice: Researching And Evaluating Lay Legal Assistance Programs, Tanina Rostain, James Teufel

Georgetown Law Faculty Publications and Other Works

In recent years a national movement to train lay advocates and advisors to assist people with their common justice problems has emerged in the United States. A host of new programs have launched that allow trained navigators and justice workers to provide legal assistance. These programs – developed in Alaska, Delaware, South Carolina, Arizona, and Utah, among other places – vary in their substantive focus, the skills they impart, and their approaches to reaching the people and communities they seek to help. The proliferation of lay legal assistance programs creates research imperatives and opportunities. These programs need to be assessed …

Histopathological Evaluation Of Geriatric Ophthalmic Veins: A Cadaveric Study, Farida Mehrhoff, Keanna Theobalt, Alla G. Barry, Robert Hillard

Student Publications

Context: The ophthalmic vein (OV) has become a source of increasing curiosity since many aspects of vascular surgery of the orbit have become feasible. At the same time, histochemical analysis of veins, in general, tends to skip the OV. Moreover, age‑related changes in the OVs remain untouched. Aims: Our research explores features of aging in the OV. Settings and Design: We immunohistochemically evaluated the superior and inferior OVs in 49 orbits of 28 formalin‑embalmed human cadavers (age 77.86 ± 13.38) without visible vascular malformations. Materials and Methods: Specimens were stained by hematoxylin and eosin. Verhoeff, laminin, and CD31 stains were …

Pembrolizumab Plus Carboplatin And Paclitaxel As First-Line Therapy For Recurrent/Metastatic Head And Neck Squamous Cell Carcinoma (Keynote-B10): A Single-Arm Phase Iv Trial, Marcin Dzienis, Peter Oppelt, Et Al.

2020-Current year OA Pubs

PURPOSE: Standard-of-care first-line treatment for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is pembrolizumab plus platinum and fluorouracil (FU). However, FU is associated with potential challenges (continuous 4-day infusion, high administration costs, and cardiovascular and gastrointestinal toxicities), creating a clinical need for alternative chemotherapy combinations. We evaluated the efficacy and safety of first-line pembrolizumab plus carboplatin and paclitaxel for R/M HNSCC in the open-label, single-arm, phase IV KEYNOTE-B10 study (ClinicalTrials.gov identifier: NCT04489888).

METHODS: Eligible adults had previously untreated, histologically or cytologically confirmed R/M HNSCC regardless of PD-L1 status, measurable disease per RECIST v1.1 by blinded independent central review …

Geriatric Nutritional Risk Index Predicts Postoperative Delirium In Elderly: A Meta-Analysis, Siye Xie, Qi Wu

Saudi Medical Journal

Objectives: To review current evidence on using the geriatric nutritional risk index (GNRI) in predicting postoperative delirium (POD) in elderly patients. Methods: The literature search was performed in core databases to include all the cohort studies on the association between GNRI and risk of POD for further meta-analysis. Results: A total of 6 studies with 4242 patients underwent this meta-analysis, which showed that the risk of POD was higher in patients with moderate and high GNRI than the ones with low GNRI (odds ratio [OR]=2.04, 95% confidence interval [CI] [1.58, 2.64], p <0.001), and moderate and high GNRI significantly increased the risk of POD in patients of 60 to 75 years or above [OR=1.98, 95%CI (1.49, 2.62), p <0.001; OR=2.79, 95%CI (1.38, 5.64), p =0.004, respectively]. Conclusion: Therefore, moderate and high GNRI increased the risk of POD in elderly patients.

Comparative Analysis Of Nutritional Quality And Microbial Contamination In Camel Milk: Evaluating Safety And Public Health Risks Between Camel Milk Obtained From Street Vendors And Farms In Saudi Arabia, Nisreen M. Abdulsalam, Ebtehal M. Alghamdi

Saudi Medical Journal

Objectives: To evaluate the nutritional quality and microbial contamination of raw camel milk sourced from street vendors and compare it with milk obtained from farms, with a particular emphasis on pathogenic organisms. Methods: Twenty samples were systematically collected from street vendors and farms between July 2022 and February 2023 and analyzed at King Fahad Medical Research Centre and the Pharmacy College, King Abdulaziz University, Jeddah, Saudi Arabia. The microbial analysis employed culture-dependent techniques for colony-forming unit analysis and isolation of microbial colonies from milk samples. Microbial identification utilized advanced methods, including VITEK-MS equipment and the MALDI-TOF technique. The chemical composition …

Disruption Of Fuz In Mouse Embryos Generates Hypoplastic Hindbrain Development And Reduced Cranial Nerve Ganglia, Carlo Donato Caiaffa, Yogeshwari S Ambekar, Manmohan Singh, Ying Linda Lin, Bogdan Wlodarczyk, Salavat R Aglyamov, Giuliano Scarcelli, Kirill V Larin, Richard H Finnell

Faculty, Staff and Students Publications

Background: The brain and spinal cord formation is initiated in the earliest stages of mammalian pregnancy in a highly organized process known as neurulation. Environmental or genetic interferences can impair neurulation, resulting in clinically significant birth defects known collectively as neural tube defects. The Fuz gene encodes a subunit of the CPLANE complex, a macromolecular planar polarity effector required for ciliogenesis. Ablation of Fuz in mouse embryos results in exencephaly and spina bifida, including dysmorphic craniofacial structures due to defective cilia formation and impaired Sonic Hedgehog signaling.

Results: We demonstrate that knocking Fuz out during embryonic mouse development results in …

Is Science For All An Elusive Goal? Disparities In U.S. Science Education, David Devraj Kumar, John L. Pecore

The Journal of the Research Association of Minority Professors

An examination of published reports on Free or Reduced-Price Lunch (FRPL) regarding Per Pupil Spending, Technology Resources, Science Course Offerings, and Race and Ethnicity Distribution in FRPL Groups shows that science for all remains an elusive goal in the United States. Science for all requires long-term solutions, including adequate fiscal resources for high FRPL quartile schools and effective policies to ensure quality science learning experiences for low-income students. Teachers in high FRPL schools need access to high-quality instructional resources, technology tools, and effective strategies to engage students in science learning. Schools should invest in technology tools like virtual reality and …

Antioxidant And Anti-Inflammatory Activities Of Ethanol And Aqueous Extracts In The Amnouy Suksomjit’S Thai Folk Remedy, Wichida Larsomsri, Pannawat Chaiyawatthanananthn, Thanaporn Intarawan, Yupa Ngankogsoong, Katanchalee Houngiam

Asian Medical Journal and Alternative Medicine

Introduction: A Thai folk remedy is traditionally used to manage many diseases, such as diabetes mellitus, hyperlipidemia, and dementia, as they are related via oxidative stress and chronic inflammation pathways.

Objectives: This study investigates the antioxidant contents, and anti-oxidation and anti-inflammation properties of ethanol and aqueous extracts of Dr. Amnouy Suksomjitʼs Thai folk remedy (RM or the Remedy).

Methods: RM and its plant ingredients were extracted with ethanol maceration and water decoction. All extracts had their antioxidant compounds measured i.e. total phenolic contents (TPC) and total flavonoid contents (TFC), activity by DPPH, ABTS^+ and FRAP assays, and anti-inflammatory activity …

Correlation Of Size And Redness Of Pterygium On Tear Film And Dry Eye Symptoms, Pakornkit Phrueksaudomchai

Asian Medical Journal and Alternative Medicine

Purpose: This study aimed to investigate the correlation of size and redness of pterygium to tear film and dry eye symptoms.

Setting/Venue: Thammasat University Hospital, Thailand

Materials and Methods: 976 patients joined a hospital-based, retrospective cross-sectional study in Thammasat University Hospital. Severity of pterygium was measured and collected by size and redness; Tear film was measured and collected by Tear meniscus height (TMH) and Tear break up time (TBUT); Dry eye syndrome was measured and collected by Ocular surface visual analogue scale (VAS), Ocular Surface Disease Index (OSDI), Oxford corneal staining scale and Meibomian gland dysfunction grading. The study was …

Analysis Of Fluid Intake During Pregnancy, Irem Dilaver, Busra Parlak Somuncu, Murat Topbas, Kubra Sahin, Medine Gozde Ustundag, Cansu Agrali Gundogmus, Gamze Can, Nazim Ercument Beyhun

Makara Journal of Health Research

Background: Pregnancy is an important process that affects the body’s daily water requirements through various mechanisms. Adequate fluid intake also plays a critical role in pregnancy. This research aimed to determine levels of water/fluid intake and influencing factors among pregnant women presenting to a university hospital in Trabzon, Türkiye.

Methods: A total of 1,082 pregnant women were included in this cross-sectional research. A questionnaire was used during the face-to-face interviews to collect data. SPSS version 23.0 software was employed during data analysis, and logistic regression was applied to identify factors that affect adequate daily fluid intake.

Results: …

Evaluation Of The Relationship Between Self-Care And Treatment Compliance In Patients With Type 2 Diabetes: A Cross-Sectional Study From Northeast Türkiye, Enver Caner, Esin Kavuran

Makara Journal of Health Research

Background: The study aimed to investigate the connection between self-care behaviors and treatment adherence among individuals with type 2 diabetes.

Methods: This cross-sectional correlational study was conducted between January and May 2022 in a public hospital involving 191 patients diagnosed with type 2 diabetes. Data were collected using the patient information form, the diabetes self-care scale, and the assessment scale for treatment compliance in type 2 diabetes.

Results: The mean self-care score was 84.57 ± 14.46 years, and the mean treatment compliance score was 79.50 ± 11.13 years, with a significant negative correlation between them (r …

Unraveling The Multilevel Dynamics Of Water, Sanitation, And Child Anthropometry In Indonesia, Rifa Kirana, Ahmad Komarulzaman

Makara Journal of Health Research

Background: Anthropometrics, reflecting nutritional status, growth, and development, are crucial elements that can predict a person’s health and well-being. However, low anthropometric measures among children under 5 years remain a significant issue in Indonesia, often influenced by various factors at the household and community levels. Access to clean water and adequate sanitation has been identified as major determinants of these adverse health outcomes. This study analyzes the relationship between anthropometric measures and access to water and sanitation at household and community levels using a multilevel analysis approach.

Methods: The study employs cross-sectional data from the Indonesian Family Life …

General And Abdominal Adiposity And Hypertension In Eight World Regions: A Pooled Analysis Of 837 Population-Based Studies With 7·5 Million Participants, Bin Zhou, James E. Bennett, Aidan P. Wickham, Rosie K. Singleton, Anu Mishra, Rodrigo M. Carrillo-Larco, Nayu Ikeda, Lakshya Jain, Ana Barradas-Pires, Rachel A. Heap, Victor P.F. Lhoste, Kate E. Sheffer, Nowell H. Phelps, Archie W. Rayner, Edward W. Gregg, Mark Woodward, Gretchen A. Stevens, Maria L.C. Iurilli, Goodarz Danaei, Mariachiara Di Cesare, Carlos A. Aguilar-Salinas, Noor Ani Ahmad, Pascal Bovet, Zhengming Chen, Albertino Damasceno, Sarah L. Filippi, Imre Janszky, Andre P. Kengne, Young Ho Khang, Kamlesh Khunti, Avula Laxmaiah, Lee Ling Lim, Lauren Lissner, Paula Margozzini

Population and Public Health Science Faculty Publications

Background: Adiposity can be measured using BMI (which is based on weight and height) as well as indices of abdominal adiposity. We examined the association between BMI and waist-to-height ratio (WHtR) within and across populations of different world regions and quantified how well these two metrics discriminate between people with and without hypertension. Methods: We used data from studies carried out from 1990 to 2023 on BMI, WHtR and hypertension in people aged 20–64 years in representative samples of the general population in eight world regions. We graphically compared the regional distributions of BMI and WHtR, and calculated Pearson's correlation …

Investigation On Production, Kinetic Modelling, Downstream Processing, And Characterization Of Microbial Dextran Using Sucrose-Rich Alternate Feedstocks, Sameeha Syed Ar

Theses and Dissertations

Microbial exopolysaccharides (EPS) synthesized by microorganisms have a wide range of applications from thickener agents in the field of food to formulations in the field of pharmaceuticals. Owing to their rheological, structural, and physicochemical characteristics in addition to its biodegradability, low antigenicity, antioxidant activities, etc., several EPS have gained research focus in recent years. Dextran is one such example of EPS, which is synthesized by lactic acid bacteria (LAB). However, its production is limited to utilization of sucrose medium with a yield of 0.3-0.4 g dextran/ g sucrose. Hence, this thesis work focuses on dextran production using sucrose-rich alternate feedstocks …

Horizontal Gene Transfer In Intergenomic Conflicts Between Bacteria And Their Genetic Parasites, Pavithra A.S

Theses and Dissertations

Bacteria are constantly infected by obligate acellular genetic parasites, such as plasmids and phages. The genetic conflicts between bacteria and their parasites, aggravated by horizontal gene transfer, exert significant ecological and evolutionary pressure on their respective genomes. The eco-evolutionary significance of parasite-derived elements on bacterial genomes is not well understood.

This study explored the genomics of plasmid-derived genetic elements such as antimicrobial resistance genes (ARGs), type II endonuclease toxin-antitoxin systems (TAs) and endonuclease colicin-like bacteriocin (CLB) operons, and phage-derived prophages of Escherichia coli using bioinformatics and developing novel hybrid agent-based models. We sequenced eight E. coli isolated from local wastewater …

Investigation On Strength Durability And Crack Healing Efficiency Of Natural Fiber Reinforced Bacterial Concrete Under Various Exposures, Rajesh A

Theses and Dissertations

Concrete is the most broadly utilized construction material due to its availability and cost. It is more susceptible to cracks, allowing chemical substances and water to enter and deteriorate the materials over time, as well as affecting the durability properties of structures. In recent years, the use of bacteria and natural fibers in concrete has not only reduced cracks but also enhanced its strength and durability.

Microbial-induced carbonate precipitation (MICP) is highly acceptable in concrete to improve rheological and crack repair properties. In the current research isolated five bacteria from various locations and subjected to basic tests such as urease …

Reconstruction Of Sharia Law Enforcement In Islamic Banking By The Sharia Supervisory Board Using A Swot Analysis Approach, Mahipal Mahipal, Yudi Wahyudin

Indonesia Law Review

The implementation of sharia principles in Islamic banking management has not always benefited. A challenge lies in the fact that the Sharia Supervisory Board's (SSB) oversight of Islamic banking has not operated at peak efficiency. Developing plans and policies for SSB's rehabilitation in Islamic banking management is the goal of this study. The literature review method and SWOT analysis was used to conduct the research. The analysis's findings indicate that the most important factor influencing SSB's presence in an organization and the management structure of Islamic banking is the frequency with which organizational internal factors—weaknesses (1.00) and strengths (0.95) of …

Perceived Medical, Social, And Psychological Issues Due To The Covid-19 Pandemic Among Elderly: A Descriptive Analysis, Khushboo Juneja, Kathan Kapoor, Ashwini Kumar, Kundangar Eshwari

Open Access archive

Elderly individuals are more likely to suffer from both short and long-term consequences of COVID19, including exacerbation of existing illnesses, psychological issues, and increased risk of death. This study aimed to understand the medical, perceived psychological, and social health problems faced by the elderly due to the COVID-19 pandemic. This hospital-based study included 225 elderly patients (aged ≥60 years) with chronic health conditions. Hypertension (70.2%) and diabetes mellitus (64.0%) were the most common morbidities among the study participants. At least 34.7% of the participants had one or more symptoms suggestive of psychological problems due to COVID-19 pandemic. Among the participants, …

Comparative Evaluation Of Tooth Enamel Surface Microhardness Exposed To Novel Modified Casein Phosphopeptide Amorphous Calcium Phosphate, Apf Gel And Gc Tooth Mousse, P Rahmath Meeral, Indumathy Pandiyan, Meignana Arumugham

Journal of Dentistry Indonesia

Objective: The acidic pH of remineralizing agents is beneficial in etching the enamel to facilitate increased remineralization. This study aims to modify the pH of Casein Phosphopeptide Amorphous Calcium phosphate to acidic and evaluate the enamel surface microhardness exposed to acidified CPP ACPF, acidulated phosphate fluoride (APF gel), and conventional CPP ACPF. Methods: The pH of conventional CPP ACPF (GC Tooth Mousse) is acidified. 24 tooth samples were assigned into three groups receiving as follows: Group 1 (n = 8) acidified CPP ACPF, Group 2 (n = 8) APF gel, and Group 3 (n = 8) CPP ACPF for four …

Developing An Ordered Logistics Regression Model For Denture Hygiene Among Elderly In Residential Care Homes, Wan Muhamad Amir W Ahmad, Ruhana Hasan, Mohamad Nasarudin Adnan, Farah Muna Mohamad Ghazali, Hazik Bin Shahzad, Nor Azlida Aleng, Mohamad Shafiq Mohd Ibrahim

Journal of Dentistry Indonesia

With a global aging population, the oral hygiene of elderly individuals in institutional settings requires unique management. Maintaining adequate denture hygiene is a critical aspect of their overall well-being, while neglecting denture hygiene can lead to various oral health issues, malnutrition, and further impacting their overall health. Objective: This paper aims to provide a preliminary overview of denture hygiene care among the elderly using an ordered logistics model. Methods: Data was obtained from 174 participants in two government institutional homes in Malaysia. The Principle Components Analysis (PCA) was used to identify significant variables and an ordered logistic model …

Leveraging The Science Of Early Life Predictability To Inform Policies Promoting Child Health, Laura M. Glynn, Sabrina R. Liu, Candice Taylor Lucas, Elysia Poggi Davis

Psychology Faculty Articles and Research

Addressing the tremendous burden of early-life adversity requires constructive dialogues between scientists and policy makers to improve population health. Whereas dialogues focused on several aspects of early-life adversity have been initiated, discussion of an underrecognized form of adversity that has been observed across multiple contexts and cultures is only now emerging. Here we provide evidence for “why unpredictability?”, including: 1. Evidence that exposures to unpredictability affect child neurodevelopment, with influences that persist into adulthood. 2. The existence of a translational non-human animal model of exposure to early life unpredictability that can be capitalized upon to causally probe neurobiological mechanisms. 3. …

Longitudinal Dietary Intake Data In Patients With Phenylketonuria From Europe: The Impact Of Age And Phenylketonuria Severity, Alex Pinto, Kirsten Ahring, Manuela Ferreira Almeida, Catherine Ashmore, Amaya Bélanger-Quintana, Alberto Burlina, Turgay Coşkun, Anne Daly, Esther Van Dam, Ali Dursun, Sharon Evans, François Feillet, Maria Giżewska, Hulya Gökmen-Özel, Mary Hickson, Yteke Hoekstra, Fatma Ilgaz, Richard Jackson, Alicja Leśniak, Christian Loro, Katarzyna Malicka, Michał Patalan, Júlio César Rocha, Serap Sivri, Iris Rodenburg, Francjan Van Spronsen, Kamilla Strączek, Ayşegül Tokatli, Anita Macdonald

School of Health Professions

In phenylketonuria (PKU), natural protein intake is thought to increase with age, particularly during childhood and adolescence. Longitudinal dietary intake data are scarce and lifelong phenylalanine tolerance remains unknown. Nine centres managing PKU in Europe and Turkey participated in a retrospective study. Data were collected from dietetic records between 2012 and 2018 on phenylalanine (Phe), natural protein, and protein substitute intake. A total of 1323 patients (age range: 1–57 y; 51% male) participated. Dietary intake data were available on 1163 (88%) patients. Patient numbers ranged from 59 to 320 in each centre. A total of 625 (47%) had classical PKU …

Ekspresi Bahasa Evaluatif Pada Artikel Ilmiah Berbahasa Indonesia, Ahmad Fadly, Untung Yuwono, Sonya Puspasari Suganda

Paradigma: Jurnal Kajian Budaya

Authors of scientific articles are faced with two opposing demands: objectivity and critical evaluation when expressing reality and truth. To date, no evaluative language mapping has been performed on Indonesian scientific articles which can accurately describe an article’s degree of objectivity so that it can be used as a tool for objectivizing and negotiating truth. Using the appraisal framework, this research aims to identify and examine these two opposing orientations as they appear in Indonesian scientific articles. The qualitative approach was applied to perform in-depth analysis of interpersonal functions in scientific articles. Data in the form of Indonesian scientific articles …

Antioxidant, Photoprotective, And Cytotoxic Activities Of Tristaniopsis Merguensis Leaf Fractions With Molecular Docking Study Of Potential Fraction, Boima Situmeang, Respati Tri Swasono, Tri Joko Raharjo

Karbala International Journal of Modern Science

Through experimental along with molecular docking techniques of potential fraction, this study intended to evaluate the essential phytochemical elements of Tristaniopsis merguensis leaflets as well as potential antioxidant, photoprotective, along with cytotoxic activities. The DPPH and ABTS tests were used to evaluate the antioxidant efficacy of the n-hexane (HPF), ethyl acetate (EPF), and methanol (MPF) fractions. Using an in-vitro solar protection factor (SPF) assessment, the photoprotective ability of T. merguensis components against UV damage was examined. Subsequently, invitro cytotoxic research were carried out against MCF-7 cell line (breast cancer line) assay. This was followed by molecular docking stimulation testing against …

Effect Of Inulin From Dahlia Tubers (Dahlia Variabilis) Extract On Insulitis Severity And Insulin Expression In Diabetic Rats, Ismawati Ismawati, Saryono Saryono, Mukhyarjon Mukhyarjon, Ilhami Romus, Veni Dayu Putri, Sri Yanti, Fitri Dyna, Nada Idzdihari Adesti

BioMedicine

Background: Dahlia (Dahlia variabilis), a widely cultivated ornamental plant in Indonesia, is known to contain 84.08% inulin in its tubers. Numerous studies have demonstrated the antidiabetic potential of inulin from various plant sources. However, most of the research is in the form of a mixture of inulin with other active substances, and no one has analyzed the effects of inulin derived from dahlia tubers. This study examines the effect of inulin from dahlia tuber extract on blood glucose levels, serum insulin expression, pancreatic tissue insulin expression, homeostatic model assessment of insulin resistance (HOMA-IR), and the extent of …

Polyphenols In Bee Products And Prevention Of Cell Senescence, Siti Nuriah Mohd Noor, Marahaini Musa, Ahmad Azlina, Siew Hua Gan, Kannan Thirumulu Ponnuraj

BioMedicine

Sustaining the continuity of cells and their homeostasis throughout the lifespan is compulsory for the survival of an organism. Cellular senescence is one of mechanisms involved in cell homeostasis and survival, and plays both important and detrimental roles in the maintenance of malfunctioned and normal cells. However, when exposed to various insults (genetic, metabolic and environmental), the cells undergo oxidative stress which may induce premature senescence, or so-called stress-induced premature senescence. Many age-related diseases are associated with premature senescence. Hence, there is growing interest in the intake of natural sources such as dietary food, which has protective functions on human …

August 30, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.