Digital Commons Network^™

Evaluating Efficacy Of Vedolizumab, Ustekinumab, And Golimumab In The Management Of Inflammatory Bowel Disease And The Combined Role Of Nutritional Therapy With Biologics: A Review, Shahed Kamal, Karan Varshney, Danielle Josefa F. Uayan, Fides Myles C. Caliwag

Ateneo School of Medicine and Public Health Publications

Inflammatory bowel disease (IBD), which encompasses both ulcerative colitis (UC) and Crohn’s disease (CD), is a major health burden worldwide. There are increasing concerns surrounding the impacts of this disease due to significant rises in the prevalence rates of IBD across the world. In consideration of the complexities of managing IBD along with this marked rise in prevalence and incidence, developing new forms of treatment for this condition has become a major priority. In recent years, a potential new form of treatment for IBD has emerged in the form of biologic therapies. While there is a high level of optimism …

The Power To Shape The “Political”, Amanda Shanor

The University of Chicago Business Law Review

The role of corporations in American life has become the focus of intense public and scholarly debate. How do corporations influence political outcomes? What norms or laws should structure corporate political participation? And who should decide what political interventions corporations make? These are vitally important questions that bear on how to deal with the pressing challenges of social media, money in politics, polarization, autocratic threats, and the influence of consolidated capital on governmental and democratic decision-making.

Most conversations about the role of corporations in politics, however, assume a definition of “political.” This key term is commonly taken for granted or …

Neurological Symptoms And Cause Of Death Among Young Children In Low- And Middle-Income Countries, Sara Ajanovic, Zachary Madewell, Shams El Arifeen, Emily Gurley, Mohammad Zahid Hossain, Kazi Munisul Islam, Afruna Rahman, Nega Assefa, Lola Madrid, R Gunturu

Pathology, East Africa

Importance: The emergence of acute neurological symptoms in children necessitates immediate intervention. Although low- and middle-income countries (LMICs) bear the highest burden of neurological diseases, there is a scarcity of diagnostic and therapeutic resources. Therefore, current understanding of the etiology of neurological emergencies in LMICs relies mainly on clinical diagnoses and verbal autopsies.

Objective: To characterize the association of premortem neurological symptoms and their management with postmortem-confirmed cause of death among children aged younger than 5 years in LMICs and to identify current gaps and improve strategies to enhance child survival.

Design, Setting, and Participants: This cross-sectional …

Physical Decline Rates: Men Versus Women, Ray C. Fair

Cowles Foundation Discussion Papers

This paper uses world records by age in running, swimming, and rowing to estimate a biological frontier of decline rates for both men and women. Decline rates are assumed to be linear in percent terms up to a certain age and then quadratic after that, where the transition age is estimated. The use of world records avoids the possible problem of survivor bias in a sample. The decline rates are smallest for rowing, followed by swimming and then running. Decline rates for women are roughly the same as those for men for the swimming events. They are slightly larger for …

Closing The Gap Between Evidence And Practice For Childhood Obesity Treatment, Alyssa M. Button, Amanda E. Staiano, Hilary K. Seligman

Population and Public Health Science Faculty Publications

No abstract provided.

Nrsg 259.01: Adult Nursing Iii, Izak A. Godoy

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Remembering My Grandmother: Rev. Maggie T. Mosley (Summer 2024), Cassandra Hawkins

Staff Residencies

Dr. Cassandra Hawkins, Associate Director of Data and Quality Management at the Institute of Child Nutrition, pursued a film photography project that invoked a sense of family and introspection about the past and the present.

Energetics Of A World-Tour Female Road Cyclist During A Multistage Race (Tour De France Femmes), Jose L. Areta, Emily Meehan, Georgie Howe, Leanne M. Redman

Clinical Research Faculty Publications

Despite the increased popularity of female elite road cycling, research to inform the fueling requirements of these endurance athletes is lacking. In this case study, we report for the first time the energetics of a female world-tour cyclist competing in the 2023 Tour de France Femmes, an 8-day race of the Union Cycliste Internationale. The 29-year-old athlete presented with oligomenorrhea and low T3 before the race. Total daily energy expenditure assessed with the doubly labeled water technique was 7,572 kcal/day (∼4.3 physical activity levels), among the highest reported in the literature to date for a female. Crank-based mean maximal power …

Determining Diabetic Kidney Disease Severity Using Traditional Chinese Medicine Syndrome Classification, Amanda Yun Rui Lam, Huang Fang Zheng, Kok Keong Teo, Xiao Hui Xin, Chieh Suai Tan, Jean Paul Kovalik, Sujoy Ghosh, Hong Chang Tan

Division of Basic Science Faculty Publications

No abstract provided.

Autonomic And Enteric Profiling May Help Predict Response To Diverse Obesity Therapies, Michael Eiswerth, Prateek Mathur, Hani Rashed, Frank Greenway, Eric Ravussin, William Johnson, Pichamol Jirapinyo, Christopher C. Thompson, Farid Kehdy, Shabnam Sarker, Le Yu Naing, Michael W. Daniels, Thomas Abell

Clinical Research Faculty Publications

Purpose: Changes in autonomic (ANS) and enteric nervous systems (ENS) may be involved in pathogenesis of obesity. We hypothesized that baseline autonomic and enteric parameters may predict outcomes of diverse obesity therapies. Material and Methods: We studied ANS and ENS physiology in 37 patients (8 male, 29 female, age 45 years, weight 129.7 kg) at 4 centers in patients undergoing medical (9: low-calorie diet) versus invasive (22: 16 sleeve, 6 bypass) and semi-invasive (6: 2 band, 2 high energy stimulation, 2 aspiration) weight loss therapies. Weight loss was reported as percent weight loss from baseline to latest values at 1 …

Effect Of Impaired Awareness Of Hypoglycemia On Glucose Decline During And After Exercise In The T1dexi Study, Jorge L. Jo Kamimoto, Zoey Li, Robin L. Gal, Jessica R. Castle, Francis J. Doyle, Peter G. Jacobs, Corby K. Martin, Roy W. Beck, Peter Calhoun, Michael C. Riddell, Michael R. Rickels

Clinical Research Faculty Publications

Context: Adults with type 1 diabetes (T1D) face the necessity of balancing the benefits of exercise with the potential hazards of hypoglycemia. Objective: This work aimed to assess whether impaired awareness of hypoglycemia (IAH) affects exercise-associated hypoglycemia in adults with T1D. Methods: We compared continuous glucose monitoring (CGM)-measured glucose during exercise and for 24 hours following exercise from 95 adults with T1D and IAH (Clarke score ≥4 or ≥1 severe hypoglycemic event within the past year) to 95 “aware” adults (Clarke score ≤2 and no severe hypoglycemic event within the past year) matched on sex, age, insulin delivery modality, and …

Covid-19 Implications On Worksite Wellness Programming, Renee A. Underwood, Angela R. Wood, Ralph J. Wood, Rylie B. Broussard, Stephanie T. Broyles

Population and Public Health Science Faculty Publications

Seven of the top ten leading causes of death in the United States are due to chronic diseases and treating these accounts for 86 percent of our nation's health care costs. The workplace offers an environment to implement chronic disease prevention strategies, such as worksite wellness programs, due to the large amount of time spent at the worksite daily by employees. As a result of COVID-19, many organizations began to change their workdays (i.e., working from home). This research sought to understand what, if any, implications the COVID-19 epidemic had on worksite wellness programming. Semistructured interviews were employed and recorded …

Evaluating The Validity Of The Portionsize Smartphone Application For Estimating Dietary Intake In Free-Living Conditions: A Pilot Study, Hanim E. Diktas, Chloe P. Lozano, Sanjoy Saha, Stephanie T. Broyles, Corby K. Martin, John W. Apolzan

Clinical Research Faculty Publications

Objective: Evaluate the validity of the PortionSize application. Methods: In this pilot study, 14 adults used PortionSize to record their free-living food intake over 3 consecutive days. Digital photography was the criterion measure, and the main outcomes were estimated intake of food (grams), energy (kilocalories), and food groups. Equivalence tests with ±25% equivalence bounds and Bland-Altman analysis were performed. Results: Estimated gram intake from PortionSize was equivalent (P < 0.001) to digital photography estimates. PortionSize and digital photography estimated energy intake, however, were not equivalent (P = 0.08), with larger estimates from PortionSize. In addition, PortionSize and digital photography were equivalent for vegetable intake (P = 0.01), but PortionSize had larger estimates of fruits, grains, dairy, and protein intake (P >0.07; error range 11% to 23%). Conclusions and Implications: Compared with digital photography, PortionSize accurately estimated food intake and had reasonable error rates for other nutrients; however, it overestimated energy intake, indicating …

Modification Of Childcare's Outdoor Setting For Toddler Physical Activity And Nature-Based Play: A Mixed Methods Study, Chelsea L. Kracht, Amanda E. Staiano, Melissa Harris, Kristin Domangue, Michelle Grantham-Caston

Population and Public Health Science Faculty Publications

Background Toddler physical activity is critical for child health, but little is known about its applications in early childhood education (ECE) centers. The aims of this study were 1) to determine if pragmatic and nature-based modifications to an ECE center's outdoor setting were feasible and acceptable, and 2) to identify barriers and facilitators of toddler physical activity at ECE centers. Methods A multiphase mixed-methods study (QUANT+QUAL) was conducted. In the QUANT study, a stepped, sequential modification of the outdoor setting, using pragmatic and cost-effective nature-based elements, was conducted with a delayed control group over 10-weeks, with follow-up assessments 3-months later …

Nutrition Education For Refugees: Successful Strategies And Barriers, Jessica Smith, Habiba Nur, Martha Archuleta, Mateja R. Savoie-Roskos, Celina Wille, Casey Coombs, Heidi J. Wengreen

Journal of Human Sciences and Extension

Nutrition education can improve nutrition and health for refugees. Extension program directors providing nutrition education to refugees were surveyed regarding successful program techniques, program challenges, and both the barriers refugees face and the strengths they possess concerning healthy eating. Researchers used grounded theory to explore the qualitative data. Hands-on, skill-based learning emerged as a main theme of successful programs. Language and cultural issues emerged as main program challenges. It is recommended that future refugee nutrition education programs provide culturally sensitive opportunities for skill-based learning.

Postharvest Characterization And Storage Of Fresh Katmon Fruit (Dillenia Philippinensis), Leonisa A. Artes, Amparo A. Wagan, Michelle E. Omana, Leonardo L. Tamisin Jr

The Philippine Agricultural Scientist

Katmon fruit has great economic potential but little is known about its postharvest behavior. This study characterized the katmon fruit after harvest so that appropriate handling may be recommended to extend its shelf life during storage or market display. Physicochemical characteristics, particularly firmness, pH, total soluble solids (TSS), titratable acids (TA), and TSS:TA ratio were evaluated during storage under room condition (22°C) and at low temperature (15°C). These characteristics were almost constant under 22°C or at 15°C for two weeks, with pH at 2.8, TSS at about 3.40°Brix, TA at 1.1 – 1.5%, and TSS:TA ratio at 3.1 – 2.04. …

The Mutual Effects Of Pinching And Promalin® On Root Architecture In Two Boxwood Species, Omer Sari, Fisun Celikel

The Philippine Agricultural Scientist

Boxwoods are constantly pinched to shape and form hedges, and Promalin® application is used to boost their shoot yield. Having good root development is crucial for the healthy development of plants; however, the effects of such applications on plant root development have generally been ignored in previous studies. Hence, this study evaluated the effects of applications on the root growth of two boxwood species (Buxus sempervirens L. and Buxus balearica Lam.) during the summer dormancy period. Pinching and Promalin® (0, 1 000, 2 000, and 4 000 ppm) were applied to one-year-old seedlings at three different times. Results showed …

Growth-Promoting Bacteria And Salicylic Acid Improve Essential Oil, Flower Yield, And Compatible Osmolyte Content Of Common Yarrow (Achillea Millefolium L.) Under Drought Stress, Mohsen Zarepour, Mohammad Mehdi Rahimi, Abdul Samad Kelidari, Moslem Abdipour

The Philippine Agricultural Scientist

Drought is one of the major constraints on agricultural productivity in arid and semiarid regions. Coping with drought stress involves several adaptations and mitigation strategies such as the use of plant-growth promoting bacteria and salicylic acid, which was examined in this study under two levels of water regimes (well-watered as control and drought stress) in southwest Iran in 2018 and 2020 on common yarrow (Achillea millefolium). Catalase levels significantly increased in response to drought stress and salicylic acid application. Salicylic acid and combined application treatment of both bacteria also resulted in a significant increase in proline compared with …

Effect Of Stocking Density On Growth, Biochemical Composition, And Blood Parameters In The Pacific Shortfin Eel (Anguilla Bicolor Pacifica) Elvers, Frolan A. Aya, John Carlo L. Unida, Luis Maria B. Garcia, Rowena R. Eguia Ma.

The Philippine Agricultural Scientist

This study examined the effect of stocking density on growth, biochemical composition, and blood parameters of the Pacific shortfin eel Anguilla bicolor pacifica. Elvers (1.95 ± 0.14 g body weight) were randomly stocked in indoor tanks and reared over 186 d at three stocking densities (0.3, 0.6, and 0.9 kg m^-3) set up in triplicates. Except for survival and biometric indices, elvers maintained at 0.3 and 0.6 kg m^-3 densities exhibited higher growth and feed utilization than those held at 0.9 kg m^-3. Yield increased with stocking density, which were significantly higher at 0.6 …

Unl Emeriti And Retirees Association Newsletter, September 2024

UNL Emeriti and Retirees Association: Newsletters and Other Materials

University of Nebraska-Lincoln Emeriti and Retirees Association Newsletter, September 2024

Ectogenesis And The Value Of Gestational Ties, Susan Kennedy

Philosophy

Ectogenesis technology would make it possible to support the complete gestational development of a human being outside the female body. Proponents argue that this technology offers a welcome opportunity to expand reproductive options for those unable or unwilling to gestate. However, by completely bypassing pregnancy, the use of ectogenesis prevents the formation of gestational family ties. Consequently, it has faced criticism for perpetuating a patriarchal view of the family that undermines the moral significance of gestation. The concern is that the introduction of this technology might result in the loss of reproductive autonomy for those who desire to experience pregnancy, …

The Epigenetic Impact Of Dietary Choline On Growth Outcomes Of Children Exposed To Gestational Diabetes Mellitus, Ismail Kadam

Dissertations, Theses, and Capstone Projects

Maternal insulin resistance and hyperglycemia lead to gestational diabetes mellitus (GDM) which can cause fetal hyperinsulinemia, ultimately leading to excessive fetal growth associated with macrosomia and increased adiposity at birth. Increased placental macronutrient transport and epigenetic changes in growth and metabolic genes affected by GDM contribute to fetal overgrowth and can result in complications such as overweight/obesity, insulin resistance/type 2 diabetes, cardiovascular disease risk factors, as well as cognitive impairment later in life. Choline, an essential nutrient, participates in lipid and energy metabolism by providing methyl groups for DNA methylation and thus may overcome the hypomethylation of growth and metabolic …

Preliminary Effectiveness Of A One-Week Summer Day Camp For Improving Children’S Health Behaviors And Psychosocial Well-Being Outcomes, Qiaoyin Tan, Yuxin Nie, Paul Son, Renee A. Underwood, Peyton Murray, Callie Hebert, K. Lynn Mckey, Chelsea Hendrick, Amanda E. Staiano, Senlin Chen

Faculty Publications

Purpose: Summer day camp offers children opportunities to grow knowledge and skills, be physically active, and have fun. Compared to healthy children, at-risk children (i.e., overweight, or with obesity and chronic health conditions) typically display less optimal health behaviors and psychosocial well-being, especially during summer months. This study examined the preliminary effectiveness of an American-Diabetes-Association-sponsored summer day camp at improving children’s health behaviors (i.e., physical activity, screen time, diet, sleep) and psychosocial well-being outcomes (i.e., quality of life [QoL], enjoyment, weight-related self-efficacy). Method: The sample consisted of 39 participants, including 19 boys and 20 girls, with majority being overweight (n …

Effects Of Intensive Treatment Of Chinese Women With Gestational Diabetes On The Risk Of Offspring Being Overweight From 3 To 8 Years Of Age, Jing Li, Rui Zhang, Cuiping Zhang, Gongshu Liu, Weiqin Li, Hui Wang, Yijuan Qiao, Zhijie Yu, Gang Hu, Juliana C.N. Chan, Junhong Leng, Xilin Yang

Population and Public Health Science Faculty Publications

No abstract provided.

Assessing Staff-Youth Interaction Quality: Using The Class To Evaluate Afterschool Programs, Joel M. Hektner, Debarati Kole, Vimbayi Chinopfuktwa, Shawn L. Carlson

Journal of Youth Development

No abstract provided.

Insights Into The Biocompatibility Of Biodegradable Metallic Molybdenum For Cardiovascular Applications-A Critical Review, Janina Mayers, Brianna Hofman, Indie Sobiech, Maria Kwesiga

Open Access Publishing Support Funded Articles

Atherosclerotic cardiovascular disease (ACD) is the leading cause of death worldwide. The gold standard of treatment is the implantation of a permanent stent implant that is often associated with complications such as thrombus formation, vascular neointimal response, and stent fracture, which altogether decrease the long-term safety and efficacy of the stent. Biodegradable metallic materials have become an attractive alternative because of the ability to facilitate a more physiological healing response while the metal degrades. Recently, Molybdenum (Mo) has been considered as a potential candidate due to its excellent mechanical and medical imaging properties. Moreover, the biomedical research studies performed to …

Broken Trust - A $500,000 Lesson In How Banks As Trustees Fail Beneficiaries While Enriching Themselves And While Regulators Ignore The Abuse, Bruce Cahan

Journal of International Business and Law

U.S. households own or control USD $140 trillion (TN).1 Their financial assets under management (AUM) are being managed today through the complex circuitry of global financial markets. Real estate, art and other assets also are being managed. For estate and wealth management planning, for security of long-term asset appreciation and asset protection against bankruptcy, divorce, death, incapacity and exposure of assets to litigation risks, lawyers recommend establishing trusts and rely on the professional expertise, responsibility and ethical clarity of corporate trustees. In the U.S., private trusts typically are formed pursuant to the trust codes of the various states, often modeled …

Access To Audiology Care In Rural And Urban Communities: A Methodology Paper, Molly Whitcomb, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

The ability of those affected by hearing loss to access audiology care is imperative as the effects of unmanaged hearing loss are deleterious, and the prevalence is high. Despite the abundance of individuals affected by hearing loss and the implications of the condition when untreated, barriers to access to care remain primarily unresolved, affecting groups disproportionately. These barriers include knowing when a hearing problem warrants intervention, transportation, geographical barriers, a lack of hearing health care providers, affordability, and insurance coverage. Rural and urban communities are each predisposed to a unique set of social determinants of health, which affect their ability …

Analysis Of The Thermal Aging Kinetics Of Tallow, Chicken Oil, Lard, And Sheep Oil, Yun-Chuan Hsieh, Hao Ouyang, Yulin Zhang, Donyau Chiang, Fuqian Yang, Hsin-Lung Chen, Sanboh Lee

Chemical and Materials Engineering Faculty Publications

Understanding the thermal aging kinetics of animal oils is of vital importance in the storage and applications of animal oils. In this work, we use four different techniques, including UV-Vis spectrometry, viscometry, impedance spectroscopy, and acid–base titration, to study the thermal aging kinetics of tallow, chicken oil, lard, and sheep oil in the temperature range from 120 ◦C to 180 ◦C. The evolutions of the UV-Vis absorbance, dynamic viscosity, electric impedance, and acid titration are discussed with the defect kinetics. The evolutions of the color centers, defects for dynamic viscosity, and electric dipoles follow second-order, first-order, and zero-order kinetics, respectively. …

The Seattle Amyotrophic Lateral Sclerosis (Als) Patient Project Database: Observational, Longitudinal, Dyadic Characterization Of People With Als And Their Partners, Suzanne C. Segerstrom, Edward J. Kasarskis

Neurology Faculty Publications

Introduction: The median survival time in ALS is approximately 3 years, but survival times range from less than a year to more than 10 years and much variance in disease course remains to be explained. As is true for physical outcomes, there is considerable variance in QOL, which is influenced by psychological health, coping, and social support, among other psychosocial factors. The Seattle ALS Patient Project Database (SALSPPD) provides a unique opportunity for researchers to address established and novel hypotheses about disease progression and QOL in ALS.

Methods: The SALSPPD is a longitudinal dataset of people with ALS (n = …