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The Utilization Of Alcohol Dehydrogenase (Adh) Enzymes In Stereocontrolled Synthesis, Gaurav Pramod Kudalkar

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Clostridium acetobutylicum alcohol dehydrogenase (CaADH) has been shown to catalyze the stereoselective reduction of a broad array of carbonyl compounds. This study uses a Hammett linear free-energy relationship (LFER) analysis to gain insight into CaADH enzyme mechanism across three substrate classes: aryl aldehydes, aryl β-keto esters, and aryl trifluoromethyl ketones. Kinetic data were collected by monitoring NADPH fluorescence, and Michaelis-Menten kinetics were applied. Hammett plots reveal that hydride transfer is rate-limiting for aldehydes and β-keto esters (ρ > 0), while it is proposed that dehydration is rate-limiting for trifluoromethyl ketones (ρ < 0). ¹³C NMR confirmed significant hydration in trifluoromethyl ketones. The …

Verbal Working Memory And Syntactic Comprehension Segregate Into The Dorsal And Ventral Streams, Respectively, William Matchin, Zeinab K. Mollasaraei, Leonardo Bonilha, Christopher Rorden, Gregory Hickok, Dirk B. Den Ouden, Julius Fridriksson

Communication Sciences and Disorders Faculty Articles and Research

Syntactic processing and verbal working memory are both essential components to sentence comprehension. Nonetheless, the separability of these systems in the brain remains unclear. To address this issue, we performed causal-inference analyses based on lesion and connectome network mapping using MRI and behavioural testing in two groups of individuals with chronic post-stroke aphasia. We employed a rhyme judgement task with heavy working memory load without articulatory confounds, controlling for the overall ability to match auditory words to pictures and to perform a metalinguistic rhyme judgement, isolating the effect of working memory load (103 individuals). We assessed non-canonical sentence comprehension, isolating …

Raman Characterization Of Elastomeric Materials, Shane Michael Drake

Theses and Dissertations

Raman spectroscopy is often used for material identification but may be used for characterization. This document focuses on using Raman measurements to characterize polymers, specifically the curing and aging mechanism for hydroxyl-terminated polybutadiene (HTPB). HTPB is a well-known elastomer used in sealants, non-slip surfaces, rocket repellants and plastic explosives. Raman spectroscopy was used to monitor urethane linkages that form from curing HTPB with a cyanate curing agent to suggest a curing mechanism for HTPB. Since this polymer is highly susceptible to oxidation, the methods used to characterize curing were also used for the aging process to see if urethane breakages …

Modeling Immune Cell Dynamics And Ecm Remodeling In Tendon Injury, Levi Gingerich

Mechanical Engineering and Materials Science Independent Study

Tendon injuries involve complex biological processes, including inflammation, cell recruitment, and extracellular matrix (ECM) remodeling. This study employs a systems biology approach to model the dynamic interplay between immune cells, cytokines, and the ECM during tendon repair. Ordinary differential equations (ODEs) are used to simulate key phases of healing under physiological and pathological stress scenarios, emphasizing the critical roles of macrophage polarization and ECM turnover. The model reveals distinct cytokine and cellular dynamics under varying stress intensities and durations, highlighting the detrimental effects of prolonged inflammation and excessive ECM degradation in pathological conditions. These findings highlight the importance of balancing …

Exploring K-3 Teachers’ Perspectives Of Effective Resources And Strategies Used To Close Student Learning Gaps In Reading, Samantha Lott-Velez

Seton Hall University Dissertations and Theses (ETDs)

This qualitative study explores the perspectives of effective K-3 teachers on the resources and strategies they use to close student learning gaps in reading. Despite decades of federal and state initiatives, including Response to Intervention (RTI), differentiation, and the Science of Reading, a significant number of students, especially those in economically disadvantaged communities, continue to struggle with reading proficiency. Through a narrative qualitative design, this study examines the experiences of highly effective elementary teachers working in an urban Title I school district to identify the most impactful instructional approaches for accelerating student reading achievement.

Data was collected through one-on-one interviews …

A Qualitative Study Of Emdr Clinician Treatment Modality Choice And Client Needs, Carole Petrides Bakke

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological qualitative research study was to explore and understand the lived experiences of clinicians practicing eye movement desensitization and reprocessing (EMDR) in the state of Nebraska and their choice of treatment modality, between the audio, visual, and kinesthetic techniques of EMDR. As an evidenced-based treatment therapy, EMDR has been shown to decrease the symptoms of distress in clients with a history of trauma and the treatment of choice for clients with a diagnosis of PTSD. A qualitative approach was used to assess the possible connection between the EMDR techniques as factors in individual preferences and …

Impact Of Disciplinary Literacy Pedagogy On Student Historical Content Learning: A Mixed Methods Research Study, Jeffrey Mayr

Dissertations

This study sought to assess if a disciplinary literacy (DL) teaching intervention could increase student historical content learning. The purpose of this study was to help make recommendations for usage of DL teaching strategies in the future. DL is a new and promising teaching strategy that has a multitude of research-backed benefits. However, DL adoption has been hampered by a lack of clarity on if DL can improve student content learning and test scores. This study used mixed methods methodology. Quantitative assessment was utilized for a quasi-experimental pre- and post-test design to assess the impact of a two-week DL teaching …

Comparing Student Outcomes Related To The Implementation Of The 3de Program, Amanda Burks

Dissertations

This study examines the impact of the 3DE program on ninth-grade student achievement in a Title I high school in Metro Atlanta. The 3DE program is a cohort-based model that utilizes interdisciplinary teaching paired with case study methodology; the program aims to support students as they make the difficult transition from middle to high school. This study focuses on two research questions, comparing the academic achievement of students in the 3DE program with those in the broader ninth grade population, measured by their scores on the Algebra I end of course (EOC) exam as well as the ninth-grade literature EOC. …

The Impact Of Verbal Discourse On General And Special Education Students In The Ninth Grade Algebra I Classroom, Lauren Raschen

Dissertations

The purpose of this research study was to determine if there was a difference in using verbal discourse methods in the Foundations of Algebra/Algebra I for the general and special education population.  This study was done in the collaborative classroom where the results of general education and special education students were compared.  The researcher also compared the results of the verbal discourse formative assessments to determine which type of verbal discourse made the greatest impact of conceptual understanding of mathematical operations using a quantitative study.  The data was collected for two formative assessments and compared using the multiple linear regression …

The Effectiveness Of Education Utilizing A Digital Patient Education Platform For Nursing Staff Working In A Military Medical Treatment Facility, Meki Bocage

Doctoral Dissertations and Projects

Currently, the use of digital health technology has been found to improve patients’ experiences, health outcomes, and quality of care. Furthermore, the Defense Health Agency (DHA) is focused on leveraging cutting-edge technologies to optimize healthcare delivery and improve patient experiences. The purpose of this evidence-based practice process improvement project supports providing educational intervention to nursing staff through videoconferencing or lecture learning opportunities. The project focused on successfully educating nursing staff from at least three MTFs on the use of a patient education platform by the conclusion of the 30-day intervention through individual web-based pre and post questionnaires. Ultimately, 15 registered …

The Impact Of 21st-Century Technology Teaching On Socio-Economically Challenged Students In Public High Schools: A Phenomenological Study, Duncan Kenneth Guishard

Doctoral Dissertations and Projects

The purpose of this qualitative, transcendental phenomenological study was to understand the lived experiences of 10 teachers who have used 21st-century technology teaching methods in three U.S. public high schools (PHS), North, South, and West in the Mid-Eastern United States. Schlossberg’s transition theory guided this study and was used to address the central research question: What essential elements of 21st-century technology teaching practices do you believe can improve students’ performance and academic success in U.S. public high schools? The three sub-questions helped uncover the teachers’ lived experiences and perspectives using 21st-century technology teaching methods in public high schools. Purposeful sampling …

Bioremediation Of Pb And Cd Contaminated Soil By Mycorrhiza And Biochar Treatment And Its Effect On Growth And Yield Of Shallot, Okti Herliana, Wilis Cahyani, Yugi Rahayu Ahadiyat

Jurnal Kultivasi

The contamination of shallots in the food chain by heavy metals such as lead (Pb) and cadmium (Cd) is caused by chemical fertilizers and pesticides. The study aimed to determine the growth and yields of shallot cultivated on soil contaminated with Pb and Cd using mycorrhiza and biochar. The study was conducted in the screen house at Jenderal Soedirman University, Faculty of Agriculture, from April to September 2020, and it was carried out using a factorial Randomized Completely Block Design that involved three replications and two factors. The first factor of mycorrhiza dosage comprised 0, 1, and 2 g/pot, and …

Bioremediation Of Pb And Cd Contaminated Soil By Mycorrhiza And Biochar Treatment And Its Effect On Growth And Yield Of Shallot, Okti Herliana, Wilis Cahyani, Yugi Rahayu Ahadiyat

Jurnal Kultivasi

The contamination of shallots in the food chain by heavy metals such as lead (Pb) and cadmium (Cd) is caused by chemical fertilizers and pesticides. The study aimed to determine the growth and yields of shallot cultivated on soil contaminated with Pb and Cd using mycorrhiza and biochar. The study was conducted in the screen house at Jenderal Soedirman University, Faculty of Agriculture, from April to September 2020, and it was carried out using a factorial Randomized Completely Block Design that involved three replications and two factors. The first factor of mycorrhiza dosage comprised 0, 1, and 2 g/pot, and …

A Novel, Direct Matrix Solver For Supersonic Boundary Element Method Systems, Cory D. Goates, Doug Hunsaker

Mechanical and Aerospace Engineering Faculty Publications

For problems with very fine surface meshes, typically the most time-consuming step of a boundary element method (BEM, also called a panel method) is solving the final linear system of equations. Many have already studied how to efficiently solve the dense, asymmetric systems which arise in elliptic BEMs. However, this has not been studied for a supersonic aerodynamic BEM, for which the governing PDE is hyperbolic. Due to this hyperbolic character, the matrix equation which arises from a supersonic BEM has a large number of identically zero elements. But the resulting linear system of equations is also not sparse in …

Shifting Frontiers: Understanding Species’ Abundance Range Shifts For Informed Conservation Strategies, T.J. Clark-Wolf

Funded Research Records

No abstract provided.

Assessing A Reading Score's Ability To Predict Pta Program Student Success, Tiffany H. Bain

Doctoral Dissertations and Projects

Admission into a physical therapist assistant (PTA) program continues to be highly competitive, with consistently more applicants than available seats. Student success is essential for maintaining CAPTE accreditation. There is limited research on admission criteria and predictors of success in physical therapist assistant education. This study aimed to determine if the Accuplacer or ACT reading test scores can predict student success (program completion and first-time NPTE-PTA) in a physical therapist assistant program using Astin’s input-environment-output (IEO) model as the theoretical foundation. This non-experimental logistic regression study used retrospective secondary data from an associate degree-level physical therapist assistant program 2016 through …

Evaluating Pharmacokinetic And Age-Related Parameters In The Static Mechanistic Model To Enhance The Accuracy Of Drug-Drug Interaction Prediction In The Geriatric Population, Jing Wang

Doctoral Dissertations and Projects

Drug-drug interactions (DDIs) can significantly impact drug efficacy, patient safety, and healthcare costs. While potentially life-threatening, DDIs are also predictable, manageable, and avoidable. Due to polypharmacy and age-related physiological changes, DDIs are most prevalent in the geriatric population. However, geriatric patients are often excluded from clinical trials for ethical and scientific reasons. DDI assessments in the geriatric population are typically replied on extrapolated from younger populations, which may not always be appropriate. This research investigates whether the computational model, particularly the static mechanistic model, can accurately and appropriately predict DDIs in the geriatric population by modifying pharmacokinetic and age-related parameters …

Advancing S2s Precipitation Outlooks Through The Weather Regime-Gaussian Mixture Model Framework, Wei Zhang

Funded Research Records

No abstract provided.

Growth And Yield Of Bok Choy (Brassica Rapa L.) Plants In Post-Rock Excavation Soils Provided With Phosphate-Solubilizing Bacteria And Manure, Cecep Hidayat, Yati Setiati Rachmawati, Dhea Rizqi Utami, Sofiya Hasani, Anna Aina Roosda, Windhy Chandria

Jurnal Kultivasi

Elevated sand and gravel mining to meet market needs causes negative impacts on the environment, soil, and biodiversity. The government issued a regulation that requires revegetation as reclamation of mineral and coal mining. The conversion needs to overcome the physical and chemical characteristics of post-rock excavation soil that can be utilized by economic value plants such as bok choy. This experiment aimed to determine the growth and yield of bok choy on post-rock excavation soil by providing phosphate solubilizing bacteria (PSB) and various manure types. The study was conducted in Margasari Village, Buah Batu District, Bandung at an altitude of …

A Wīnak Perspective On Cosmovisíon Maya And Eco-Justice Education, Arcia Tecun

Maya America: Journal of Essays, Commentary, and Analysis

This article responds to questions of relational ethics in Indigenous mobility with a critically conscious approach to cosmovisíon Maya in Soonkahni (Salt Lake Valley). An urban and mobile Mayan positionality, identified as Wīnak, guides an analysis of complex Indigenous experiences, and possibilities found in Eco-Justice. The limits from the prevailing and dominant colonial logics of conservation and environmentalism are re-imagined through Indigenous approaches to ‘Earth Wellbeing’. The application of critically conscious cosmovisíon Maya reveals a simultaneous challenge to systems of power, and to formations of an Indigenous relational ethic that is both locally meaningful and globally relevant. This essay concludes …

Identification And Profiling Of Socioeconomic And Health Characteristics Associated With Consumer Food Purchasing Behaviours Using Machine Learning, Daniel Burke, Martin Boudou, Jennifer Mccarthy, Majid Bahramian, Courage Krah, Christina Kenny, Paul Hynds, Anushree Priyadarshini

Articles

Food systems and food-related policies influence food consumption, dietary patterns, and human and environmental health. Consumers play a vital role in enhancing health and sustainability through their purchasing choices. To identify and cluster food purchasing behaviours and map relationships, a cross-sectional survey was conducted across Ireland with a sample size of 957 adults. Two-step cluster analysis, generalised linear models, and recursive partitioning and regression trees were used to elucidate adherence to identified food purchasing behavioural clusters. Three clusters (‘food quality’, ‘taste’, and ‘price’) were identified based on food purchasing priorities and statistically categorised. ‘Food quality’ members were significantly less likely …

Butte Priority Soils Operable Unit (Bpsou) Draft Final 2022 Insufficiently Reclaimed Sites Sampling Bres No. 32 – Corra 2 Dump Site Evaluation Summary Report, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Exploring Dependence Of Rapid Thermal Annealed Ag/Ito Bilayer Films Properties On The Systematic Ag Layer Thickness Increment For Bifacial Czts Solar Cell Application, Emmanuel R Ollotu, Justine Nyarige, Margaret E Samiji, Nuru R Mlyuka

Tanzania Journal of Science

This study investigated the impact of Ag layer thickness on the properties of rapid thermal annealed Ag/ITO bilayer films, aimed at addressing conductivity loss in ITO substrates used as a back contact for optoelectronic applications, such as bifacial CZTS solar cells. Ag layers of varying thickness (10 nm, 20 nm, 30 nm, and 40 nm) were sputter-deposited onto a commercially acquired ITO-coated glass substrate and rapidly thermally annealed. The samples’ characterization was performed using AFM, XRD, four-point probe, Hall Effect measurements, and UV-VIS-NIR spectrophotometry. Results indicated that thinner Ag layers exhibited relatively stable surfaces with uniformly distributed grains, smaller roughness, …

Predicting Students At Risk Of Dropping Out In The College Of Medicine At Mohammed Bin Rashid University Of Medicine And Health Sciences. A Machine Learning Approach To Understand Attrition Factors Over The Past Seven Years, Moza Sulaiman Al-Zaabi

Theses

This master’s thesis investigates student attrition within the College of Medicine at Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU) by applying the CRISP-DM methodology to analyse a dataset of 19 variables and around 2,000 records from Student Admission and Academic Performance sources. Although the dataset was relatively small, several machine learning models were developed to predict students at risk of dropping out, including Logistic Regression, Decision Trees, Support Vector Machines (SVM), and Artificial Neural Networks (ANN). Of these models, the ANN model, particularly when combined with Principal Component Analysis (PCA), achieved the highest performance with an accuracy …

Rooted In Identity: A Phenomenological Qualitative Study Describing The Pre-Freshman Self-Esteem Experiences Of African American Female Students Entering Historically Black Colleges And Universities, Wanda Minor

Doctoral Dissertations and Projects

This qualitative phenomenological study aimed to describe the pre-freshman self-esteem experiences of African American (AA) female students at Historically Black Colleges and Universities (HBCUs). The study explored the experiences of AA women and the factors that contribute to the development of their self-esteem before their enrollment as students in HBCUs. Literature suggests that numerous issues, including racial discrimination and prejudice, cultural stereotypes, socioeconomic concerns, historical and intergenerational trauma, beauty standards, and institutional and systemic hurdles, have affected their self-esteem (Woods-Giscombe, 2010). However, there was a void in addressing the issues AA women face in college, particularly students at HBCUs. This …

Wildlife Factors And Zoonotic Spillover In Sub-Saharan Africa, Bernard Mgba

Doctoral Dissertations and Projects

Zoonotic spillover, the transmission of infectious pathogens from animals to humans, is a critical public health concern in Sub-Saharan Africa. This study examines the role of wildlife factors in zoonotic spillover within this region, highlighting the complex interplay between human-wildlife interactions, environmental changes, and emerging zoonotic diseases. The research underscores that Sub-Saharan Africa is particularly vulnerable due to its rich biodiversity, cultural practices involving wildlife, and socioeconomic challenges. Factors such as habitat encroachment, wildlife consumption, and inadequate health infrastructure contribute to the heightened risk of zoonotic spillover. The study employs an online survey followed with a contextual analysis, and socioeconomic …

A Case Study Exploring Implementation Of Gamified Adaptive Learning Technology As A Response To Instruction And Intervention (Rti²) Strategy In Elementary Mathematics Education, Tina Marie Clowser

Doctoral Dissertations and Projects

The purpose of this single instrumental case study was to understand educators’ implementation of gamified adaptive learning programs in mathematics education as an intervention (RtI²) strategy for public elementary (K-5) teachers in a rural city school district in the Western United States. The study's central research question explored how educators implemented gamified adaptive learning technology as an intervention (RtI²) strategy in public elementary mathematics education. A single instrumental case study design was used for this study to illicit implementation strategies while uncovering successes, challenges, and barriers for in-service public elementary school educators. Data were collected from twelve participants through individual …

The Correlation Between The Degree To Which Teachers Perceive Their Administrators As Exhibiting Collaborative Leadership Style Traits And Teacher Leader Job Satisfaction Levels, Megan M. Moffa

Doctoral Dissertations and Projects

The purpose of this quantitative, predictive correlational study was to determine the predictive relationship between administrators’ use of collaborative leadership factors as perceived by teacher leaders and teacher leaders’ job satisfaction levels. The study was framed by collaborative leadership theory and job satisfaction theory and adds to the empirical evidence by examining the connection between administrators’ use of collaborative leadership and teacher leader needs. The research question explored how accurately teacher leader job satisfaction levels can be predicted from perceived administrator use of collaborative leadership traits. The study consisted of 112 pre-kindergarten through 12th grade teacher leaders in rural, suburban, …

A Transcendental Phenomenological Study Of Faculty Perceptions Of A Humanistic Classical Education, Nils Ivan Borquist

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand the descriptions of experiences for faculty members at classical education curriculum academic institutions at the PreK-12 school level. The descriptions of experiences were defined as phenomenal experiences of faculty through the subjective lens. The theory guiding this study was the humanistic learning theory of education as it focuses on self-directed and self-evaluative classwork as well as the common use of canonical works to cultivate a desire for students to learn and study great texts for their entire lives. The Central Research Question asked “How do faculty at classical education institutions …

Is Learning Relative? Exploring Student Learning In A Special Relativity Digital Game Case Study, Meredith Rae Kunz

Doctoral Dissertations and Projects

The purpose of this embedded single case study was to explore how undergraduate students learn special relativity theory in a digital game at Midwest College. The theory guiding this study was Sweller’s cognitive load theory as it applies to how students learn in a digital game environment. The central research question was: How do students learn special relativity theory in a digital game environment? I conducted a qualitative embedded single case study at a small liberal arts college in the Midwest under the pseudonym of Midwest College. Purposive and criterion sampling was used to select participants. This embedded case study …