Digital Commons Network^™

Liquid Chromatography-Mass Spectrometry Based Metabolomics, Lipidomics And Epitranscriptomics., Raobo Xu

Electronic Theses and Dissertations

Metabolomics and lipidomics are the comprehensive studies of metabolites and lipids in cells, biological fluids, tissues, or organisms. These distinct chemical fingerprints are left behind by cellular processes. Epitranscriptomics is the field that focuses on examining chemical modifications on RNA molecules at the transcriptome level. Liquid chromatography-mass spectrometry (LC-MS) has been widely used in those omics studies. In this dissertation, I developed and applied both untargeted and targeted approaches using LC-MS based various analytical platforms to conduct omics studies. Firstly, I investigated caffeine metabolites in human urine and discovered three potential functional biomarkers to differentiate the stages of alcohol-associated liver …

A Little Bit Of Everything: Persistence Though The Pre-Medical Pipeline For First And Continuing Generation Students., Tana R. Didelot

Electronic Theses and Dissertations

This qualitative research study examines pre-medical college student persistence in their pathway to medical education. Through the framework of Terenzini and Reason’s College Student Persistence Model (2005), this work sought to understand the pre-college experiences, campus support factors, and external environments that help pre-medical college students to continue toward their goal of medical school entry. This study included pre-medical undergraduate students in the campus context of one public institution in the Southern Unites States. Pre-medical upperclassmen students were interviewed using a semi-structured protocol developed with the persistence framework. The analysis was conducted to obtain a more nuanced understanding of the …

Spectrum Optimization For Advanced Air Mobility Communications Using Deep Reinforcement Learning., Rafael D. Apaza

Electronic Theses and Dissertations

As aviation operations expand and new participants enter the National Airspace System (NAS), the demand for aeronautical communications will experience a significant rise. This surge is propelled by increased air travel and the emergence of Urban Air Mobility (UAM) operations, a subset of Advanced Air Mobility (AAM). UAM aims to facilitate intra-city transportation of people and cargo utilizing remotely piloted aircraft capable of electric vertical takeoff and landing operations. The growing dependence on efficient wireless communication systems underscores the critical importance of intelligent spectrum allocation and effective airspace management to ensure safe, seamless, and technologically advanced air operations. However, the …

How White Supremacy Travels Through Time: Anti-Literacy Laws, Dei Bans, And The Issue Of Black Self-Determination In Public Health., Nicole V. Ford

Electronic Theses and Dissertations

This dissertation used a qualitative policy content analysis (PCA) of historical anti-literacy laws and modern DEI bans to answer two research questions: What is the connection between anti-literacy laws and DEI bans? How do anti-literacy laws and DEI bans create an environment that maintains white supremacy? A PCA exercise informed the analysis of historical anti-literacy laws in South Carolina (1834), Georgia (1829), North Carolina (1830), Louisiana (1830), Virginia (1831), and Alabama (1833) and modern DEI bans in Texas (2023), Alabama (2024), and Florida (2023) to find the connection between the laws. Findings from this dissertation illustrate how white supremacy operates …

Development Of A Square Wave Voltage Field-Oriented Controller For A Linear Vapor Compressor., Thomas Everson

Electronic Theses and Dissertations

In this thesis, a novel control strategy for an inverter-driven linear compressor system is proposed in which the overall electrical losses of a coupled inverter-linear motor system are reduced through the use of a modified square wave inverter modulation scheme to minimize inverter switching losses at the expense of a modest increase in conduction losses. The controller is based on a single-phase field-oriented control strategy, and to achieve the FOC control objectives, the fundamental and dc components of the applied square wave voltage are matched to the corresponding values requested by the current controller. To validate the efficiency improvements offered …

Nickel Electrocatalysts On Carbon Supports For The Hydrogen Evolution Reaction., Mohan Paudel

Electronic Theses and Dissertations

Hydrogen is an important energy storage alternative to fossil fuels due to its high energy density. Currently, most hydrogen is produced through petroleum feedstocks, which produce large amounts of carbon dioxide. However, a more eco-friendly method is the electrocatalytic splitting of water into hydrogen and oxygen. Efficient catalysts for the hydrogen evolution reaction (HER) are typically platinum group metals, which are rare and expensive. There is growing interest in developing HER electrocatalysts with earth-abundant metals for water electrolysis. Nickel, which lies in the same group in the periodic table as Pt and has similar chemical properties, is explored extensively for …

Modeling And Understanding Of Additive Manufacturing Periodic Cellular Structures With Heterogeneity: Property, Quality And Design Strategy., Naresh Koju

Electronic Theses and Dissertations

Lightweight cellular structures with their higher per mass performance capability, multifunctional designability and property tolerability are gaining much wider adaptation in many engineering applications ranging from aerospace, defense, biomedical, automotive to sports. However, to achieve the desired performance levels careful design must be carried out. The experimental-based empirical design often involves high manufacturing cost, and there are also certain information/knowledges about the cellular deigns that could not be easily obtained experimentally, such as the deformation local fracture initiation. Similarly, numerical modeling-based design approach commonly suffers from high computation cost and the lack of inverse designability. In addition, numerical models often …

Students Participating As Ambassadors For Research In Kentucky (Spark): A Health Equity Undergraduate Research Training Program, Ariel A. Arthur, Rebecca L. Delacerda Allen, Fidelis Y. Sesenu, Maxwell A. Groznik, Carrie B. Oser, Madeline Dunfee, Philip A. Kern, Nancy Schoenberg

UK CARES Faculty Publications

The Students Participating as Ambassadors for Research in Kentucky (SPARK) program provides novel health equity research training and targeted mentorship for undergraduates, particularly those from groups underrepresented in the biomedical and behavioral research and workforce. SPARK aims to address inadequate diversity in the medical and scientific research fields by providing comprehensive research mentorship and skill-building. Unlike most existing research training programs that are brief, focus on laboratory research, or are limited to graduate students and junior faculty, SPARK delivers a 16-month intensive behavioral and population health science training, equipping students with needed tools to conceptualize, plan, execute, and analyze their …

Methanogenesis Kinetics Of Organic Matter Of The Leachate In An Up-Flow Anaerobic Sludge Blanket Reactor, Mohamad Ali Fulazzaky, Ali Yuzir, Tiffany L. Messer, Agus Sofyan

UK CARES Faculty Publications

Understanding the treatment of leachate mediated by the development of anaerobic sludge makes it possible to create an effective design process of biodegradation technology. This study used an up-flow anaerobic sludge blanket (UASB) reactor equipped with a gas–liquid-solid separator to capture CH4 for treating landfill leachate to improve understanding of methanogenesis kinetics of organic matter. The performance of UASB was able to remove 154.75 g/L of chemical oxygen demand (COD) content of the leachate originally anticipated to emit 2.99 L of CH4 production into the atmosphere. The trend in the variation of internal mass transfer (IMT) factor was close to …

Nuclear Energy Is Clean And Safe Energy, Katie Morland

Op-Eds from ENSC230 Energy and the Environment: Economics and Policies

From the grappling fear of horrific meltdowns to the promise of new innovative advancements, nuclear energy has been surrounded by misunderstandings and myths for decades. A non-partisan approach from media outlets is essential for having a well-balanced understanding of how nuclear energy works and why it is good for our consumption.

Despite bias concerns that are leading to misunderstanding, nuclear energy offers a wide range of reliable cleaner types of energy. Moving forward we need to ask ourselves are we going to keep letting misinformation and misconceptions stop us from developing better advancements in nuclear energy for cleaner energy use …

The Case For E15: A Cheaper, Cleaner Fuel, Cassidy Skillett

Op-Eds from ENSC230 Energy and the Environment: Economics and Policies

In its name, “E” indicates that the fuel contains ethanol and “15” communicates that 15% of the gasoline blend is ethanol. When Nebraskan drivers pull up to the gas station, they can buy cheaper and cleaner E15. In 43 states - drivers are not so lucky. A new bill would end fuel discrimination of E15 at refueling stations nationwide.

This change is long overdue and would allow E15 to be available year-round in all states rather than just during the winter.

Zoning Regulations Are Harming Nebraska’S Wind Energy Future, Carter Probst

Op-Eds from ENSC230 Energy and the Environment: Economics and Policies

Nebraska is a prime location for renewable energy sources, such as wind. According to Climate Central, a policy-neutral non-profit, “While Nebraska ranks fourth among U.S States for potential wind energy generation, it ranks 15th in installed capacity.” What is the number one reason Nebraska has not fully tapped into its potential, which would have numerous economic and climate benefits? Harsh zoning regulations at the county level, fueled by misinformation, have made installation of wind turbines nearly impossible across multiple counties in Nebraska.

Greet Vs. Corsia: The Future Of Sustainable Aviation Fuel, Christian Curtis

Op-Eds from ENSC230 Energy and the Environment: Economics and Policies

With the country buzzing from the shocking result of the presidential election, not much ink is being spilled about the upcoming conclusion of a months-long showdown between agriculture-state lawmakers and environmentalists. The bone of contention? What modeling system will be used to calculate sustainable aviation fuel (SAF) emissions. President Biden’s IRA provides for a $1.25/gallon tax credit for any fuel qualifying as SAF; would it surprise you that environmentalists and big industry don’t see eye to eye on what counts as “sustainable”?

Learning To Represent Temporal Dynamics And Generative Factors For Intelligent Visual Navigation, Sahand Khoshdel

All Theses

Visual navigation systems are crucial in various applications, including autonomous driving, unmanned aerial systems (UAS), and industrial automation. For these systems to operate efficiently in dynamic environments, they must not only interpret complex surroundings but also anticipate changes over time. Temporal prediction—forecasting environmental changes like moving obstacles or shifting lighting conditions—enables navigation systems to act proactively, enhancing both safety and performance. This dissertation investigates representation learning methods both as a backbone feature extractor for RL agents as well as a proxy for systems oriented for Explainable AI (XAI). Two main projects are presented as case studies to achieve the aforementioned …

Shifting Perspectives With Procedural Modeling Techniques And Vertex Animated Textures For Real-Time Interactive Morphing, Stephanie Schulze

All Theses

As humans experience reality, they intake external stimuli using sensory receptors to process information, forming a perception. Perceptions are subjective and shape each individual’s reality. Naturally then, by changing one’s perceptions, their experience of reality is altered, for better or worse. To emphasize the idea that perception is malleable and encourage a mindset of questioning alternative ways to look at a situation, an interactive experience in Unreal Engine is developed where a dull cityscape morphs and transforms into a surreal oversized nature scene. Procedural modeling techniques are used to create a variety of morphing assets, while Vertex Animated Textures are …

Environmental Justice Indicators: Evaluating Their Effectiveness In Identifying At-Risk Communities For Drinking Water Violations, Rae Cade, Danlin Yu, Kyle Whyte, Pankaj Lal, Cortni Borgerson

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Despite improvements to environmental protection initiatives, millions of Black, Indigenous, and other people of color (BIPOC) continue to live in communities that are disproportionately affected by environmental contamination. Environmental Justice (EJ) screening tools, such as CalEnviroScreen, EJ Map, and PennEnviroScreen, have been developed to help state and federal governments gauge the extent of EJ in their jurisdictions. These screening tools have propelled the EJ advocacy initiative, illustrating the historic and ongoing disproportionate effects of contamination in many BIPOC communities. Yet, screening tools and their indicators vary, and we must understand how these tools and indicator choices differently identify at-risk communities, …

Net Evaporation-Induced Mangrove Area Loss Across Low-Lying Caribbean Islands, Isamar M. Cortés, Jorge Lorenzo-Trueba, Andre S. Rovai, Robert R. Twilley, Mark Chopping, Temilola Fatoyinbo

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Although mangroves provide many beneficial ecosystem services, such as blue carbon storage and coastal protection, they are currently under threat due to changes in climate conditions, such as prolonged drought exposure. Under drought conditions, evaporation exceeds precipitation and high soil salinities can lead to stunted growth and die-back. To quantify this interplay, we developed a database for low-lying and uninhabited mangrove islands in the Caribbean under various evaporation and precipitation regimes. We extracted physical and biological information from each island using remote sensing techniques and coupled it with a process-based model. We used this database to develop a model that …

The Climatic Pattern Of East Asia Shifted In Response To Cratonic Thinning In The Early Cretaceous, Wenbo Wang, Xu Chu, Jian Zhang, Ying Cui, Xuegen Chen, Yue Wang, Shangguo Su

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

In response to westward subduction of the Paleo-Pacific, the North China Craton experienced the uplift of an eastern coastal plateau followed by subsidence in the Early Cretaceous, which potentially drove a shift in climatic patterns. Here we use the oxygen isotope ratios of garnets from magmatic-hydrothermal ore systems to infer the origins and signatures of mineralization fluids during this tectonic transition. The garnet oxygen isotope values range from approximately –11.4 to +13.5‰, with extremely depleted oxygen isotope ratios exclusively found in the northern margin, indicating extensive involvement of meteoric and lacustrine fluid in the back-arc hinterland. This geological record aligns …

Intellectual Property Liability For Businesses In The Age Of Ai: What New Liabilities Businesses Using Ai Could Face And The Possible Methods Of Self-Protection, Elizabeth Anne Henderson

Michigan Business & Entrepreneurial Law Review

The invention of Artificial Intelligence (“AI”) has triggered a wave of copyright and trademark litigation that will likely shape the intellectual property laws governing AI for the foreseeable future. Lawsuits against AI giants like Meta and OpenAI stand to declare popular uses of AI as actionable infringement as well as possibly reshape how copyright and trademark law view concepts, such as fair use and derivative works in the age of technology. Meanwhile, businesses are pushing forward rapidly with adopting AI and implementing its use in everyday functions. For many of these businesses, AI is a highly desirable but poorly understood …

Unveiling Misconceptions Of Tunneling: Market Capitalization-Based Analysis, Sang Yop Kang

Michigan Business & Entrepreneurial Law Review

In internal transactions between affiliated companies, there are two opposite directions of wealth-transfer: (1) in the “forward transfer of wealth” (FTW), the wealth-transfer arises from an affiliated company where a controller’s “economic interest” (i.e., “cash-flow right”) is smaller relative to another affiliated company where the controller’s economic interest is larger; (2) in the “reverse transfer of wealth” (RTW), the wealth-transfer arises from an affiliated company where a controller’s economic interest is larger relative to another affiliated company, where the controller’s economic interest is smaller. This Article puts forward a new finding that the extent of internal-transaction tunneling is affected not …

Reducing Token Redundancy In Video-Language Models Via Memory Consolidation Algorithm, Matt Couts

Electrical Engineering and Computer Science Undergraduate Honors Theses

Video Question Answering (VideoQA) focuses on developing mod- els capable of engaging in natural language conversations about video con- tent. Current state-of-the-art typically analyze videos frame-by-frame, a process that is both computationally and memory-intensive. Integrating the Atkinson-Shiffrin memory model with Video Language Models has demon- strated potential for enhancing video understanding capabilities. Reducing the number of frames processed by the model is a crucial operation in this approach, which is achieved by a memory consolidation algorithm. This al- gorithm condenses a video sequence into a small set of representative frames which capture the essence of the video content. However, due …

Striking A Balance: Market Shock & Responses In Automotive Components Manufacturing, Emma Lane Mcgahey

All Theses

This thesis examines the effects of extreme market shocks on supply chain dynamics within the automotive industry. Through an analysis of demand data from an automotive manufacturer to its component suppliers (January 2018 to May 2024), the study investigates the relationship between market shocks and supply chain responses, providing insights into how auto components inventory management handles downstream responses to market shocks. With supporting public data—from FRED, BLS, and the U.S. Census Bureau resources—we explore two primary relationships: the impact of market shocks on the Average Standard Deviation of Demand (SDO) and the effect of demand variability on expedited pricing …

The Ugly Rhetoric Of Dobbs, Or, Why Jack Balkin Is History, Andrew Koppelman

William & Mary Bill of Rights Journal

This Essay has three claims. First, I want to emphasize an underappreciated ethical virtue elicited by the practice of rhetoric: it demands that the speaker get out of his own head and focus on his audience and what they care about. History matters because it speaks to us. It tells us who we are and why we are doing what we are doing. The rhetorical deployment of historical narrative in political discourse can help to forge a collective identity in which we all can recognize ourselves, and so make the polity more inclusive. Second, if this aspect of rhetoric is …

Resting-State Brain Activity And Its Relationship To Mental Health In Epilepsy Using Fmri, Florian Gobellan Rodriguez

McNair Scholars Research Journal

No abstract provided.

Evaluating The Efficiency Of Lossless Compression Algorithms Across Multiple Formats In Archival Compression, Matthew Gonzales

McNair Scholars Research Journal

Data storage or retention is an essential part of all business operations. Modern companies opt to store user data seven years or more after it is deleted and even longer when it’s still being hosted. Therefore, when storing files for long periods of time compression becomes an essential step in reducing cost and total file storage. Compression is the strategic removement of portions of data while ensuring that enough data is left behind to reconstruct the file during decompression. This experiment seeks to identify potential benefits of compression in groups of files of differing formats in comparison to individual file …

Postpartum Depression In North American Ghanaian Women, Natalie Bawuah

McNair Scholars Research Journal

No abstract provided.

Prioritizing The Parent Perspective: A Mixed Methods Approach To Deconstructing Learning Deficiencies Within Marginalized And Underserved Communities, Zea Wallace

McNair Scholars Research Journal

No abstract provided.

An Alternate Way Of Factoring Mathematical Objects And The Mystery Behind Free Resolutions, Tyler Trujillo

McNair Scholars Research Journal

No abstract provided.

Notes From The Director, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Letter From The Vice President For Research And Innovation, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.