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Articles 79291 - 79320 of 79599
Full-Text Articles in Entire DC Network
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the baseline F18-FDG PET/CT findings of individuals diagnosed with giant cellarteritis (GCA) and to explore its association with clinical findings and classification criteria.Materials and methods: We analysed data from patients who underwent F18-FDG PET/CT scans to investigate large vessel (LV)involvement between 2010 and 2019. Only patients with a clinical diagnosis of GCA and at least 6 months of follow-up were included.We compared initial clinical features and laboratory findings based on the presence of LV vasculitis on PET/CT and the maximumstandard uptake value (SUVmax) of vascular territories.Results: Twenty-nine patients (median age at diagnosis: …
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Turkish Journal of Medical Sciences
The objective of this study is to evaluate the clinical presentations and adverse outcomes of Coronavirus Disease 2019 (COVID-19) in patients with systemic sclerosis (SSc) and assess the impact of SSc features on the clinical course of COVID-19.Materials and methods: In this multicenter, retrospective study, SSc patients with COVID-19 were included. Clinical features of SSc, along with detailed COVID-19 data, were extracted from medical records and patient interviews.Results: The study included 112 patients (mean age 51.4 ± 12.8 years; 90.2% female). SSc-associated interstitial lung disease (ILD) was evident in 57.1% of the patients. The findings revealed hospitalization in 25.5%, respiratory …
The Effects Of On-Pump And Off-Pump Coronary Artery Bypass Surgery On Oxidative Stress And Cerebral Oxygenation: A Prospective Observational Study, Ökkeş Hakan Mi̇ni̇ksar, Sameh Alagha, Ferit Çi̇çekçi̇oğlu, Mehtap Honca, Ayşe Yeşim Göçmen
The Effects Of On-Pump And Off-Pump Coronary Artery Bypass Surgery On Oxidative Stress And Cerebral Oxygenation: A Prospective Observational Study, Ökkeş Hakan Mi̇ni̇ksar, Sameh Alagha, Ferit Çi̇çekçi̇oğlu, Mehtap Honca, Ayşe Yeşim Göçmen
Turkish Journal of Medical Sciences
In this prospective observational study, our goal was to investigate the relationship between serum levels of oxidative stress (OS) parameters and regional cerebral oxygen saturation (rSO2) in addition to evaluating postoperative clinical outcomes among patients undergoing coronary artery bypass graft surgery (CABG).Materials and methods: This study comprised 64 adult patients undergoing elective CABG (on-pump [n = 48] and off-pump [n = 16]) procedures. Serum OS levels and rSO2 values were measured intraoperatively at three specific time points: T1 (after induction), T2 (15 min before aortic cross-clamp removal or the final distal anastomosis), and T3 (15 min after aortic cross-clamp removal …
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
Turkish Journal of Medical Sciences
In open heart surgery, sternotomy causes inflammation in tissues, and inflammation causes postoperative pain. This study aims to examine the effects of bilateral erector spinae plane (ESP) blocks on postoperative extubation time and laboratory parameters in open heart surgery.Materials and methods: The study was managed using retrospective data from 85 patients who underwent open-heart surgery. Patients who received intravenous analgesia and were transferred to the intensive care unit with intubation were included in the study. Two groups were formed: those who received preoperative bilateral ESP block (ESB) and those nonblock (NB). Statistical significance was investigated between ESB and NB in …
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Turkish Journal of Medical Sciences
Extracorporeal blood purification (EBP) therapies have shown promise as potential rescue treatments for patientswith septic shock. However, precise evidence regarding their effectiveness is lacking. This case-control study aimed to evaluate the 28-day survival benefit of a resin cartridge-based EBP therapy compared to conventional therapies in patients with septic shock.Materials and methods: The study sample was collected retrospectively from the medical records of patients admitted to the intensivecare unit (ICU) between 2015 and 2020. The study included patients with septic shock aged ≥18 years who had ICU stays >96 h andexcluded those lost to follow-up by 28 days or readmitted. First, …
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Turkish Journal of Medical Sciences
Isokinetic strength assessment of the rotator cuff muscle is frequently applied in a variety of shoulder postures, butnone of these consider muscular architecture, which is one of the most important aspects of improving strength development. This studyaimed to examine the test and retest reliability and validity of the muscle architecture-based position (MABP), which is 25° abductionand 20° external rotation, in healthy subjects to be able to select a better isokinetic assessment position for shoulder rotator cuff muscles.Materials and methods: A total of 54 healthy males with a mean age of 21.0 ± 1.2 years and mean body mass index of …
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Turkish Journal of Medical Sciences
The treatment for multiple sclerosis (MS) does not cure the disease, but it is intended to reduce the intensity, duration, and frequency of symptoms. Rehabilitation therapy (RT), including an individualized physical therapy program (PTP) and adapted occupational therapy (OT), has benefits in terms of aerobic capacity, muscle strength, coordination, and ability to perform activities of daily living (ADL). The primary objective of this study was to examine the efficacy of RT comprising PTP, OT, and drug treatment (DT) versus DT alone in patients with MS. Another objective was to highlight the importance of continuing the PT and OT at home, …
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
Turkish Journal of Medical Sciences
Trunk control, which plays a key role in balance and mobility, decreases in patients with multiple sclerosis (PwMS) and many parameters such as sensory, motor, and musculoskeletal systems affect trunk control. The aim of this study was to compare trunk control, spinal mobility, and spinal posture in PwMS with healthy controls and investigate the relationship between trunk control with spinal posture and spinal mobility in PwMS.Materials and methods: The study was completed with 38 PwMS and 38 healthy controls with matched age and sex. Trunk control was evaluated with the Trunk Impairment Scale (TIS). Spinal posture and mobility were evaluated …
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Turkish Journal of Medical Sciences
Management of asymptomatic kidney stones is an ongoing debate with follow-up and treatment guidelines based on low-level evidence. Our aim was to evaluate current management of asymptomatic urinary stones.Materials and methods: A 70-question survey was designed in collaboration with European Association of Urology, Young Academic Urologists, Section of Uro-Technology and Section of Urolithiasis groups and distributed. Responders filled out hypothetical scenarios from 2 perspectives, either as treating physicians, or as patients themselves.Results: A total of 212 (40.01%) responses were obtained. Median responder age was 39 years. 75% of responders were interested in “urolithiasis”. 82.5% had never experienced a renal colic, …
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Turkish Journal of Medical Sciences
Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18–25 years (n = 20); group 2, age 26–35 years (n = 20); and group 3, age ≥35 years (n = 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology …
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Turkish Journal of Medical Sciences
In this study, it was aimed to retrospectively compare the effect of greater occipital nerve (GON) block performed with ultrasonography using low (0.3%) and high (0.5%) concentrations of bupivacaine on pain scores and patient satisfaction in chronic migraine (CM).Materials and methods: The mean number of days with pain, the mean duration of pain in the attacks, and the highest numerical rating scale (NRS) scores recorded in the 1 month preblock and 1 and 3 months postblock of 80 patients (40 for Group 1, 0.3% bupivacaine; 40 for Group 2, 0.5% bupivacaine) who underwent ultrasonography-guided GON block were recorded from the …
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the performance of contrast-enhanced mammography (CEM) and dynamic breast MRI techniques for diagnosing breast lesions, assess the diagnostic accuracy of CEM’s using histopathological findings, and compare lesion size measurements obtained from both methods with pathological size.Materials and methods: This prospective study included 120 lesions, of which 70 were malignant, in 104 patients who underwent CEM and MRI within a week. Two radiologists independently evaluated the MR and CEM images in separate sessions, using the BI-RADS classification system. Additionally, the maximum sizes of lesion were measured. Diagnostic accuracy parameters and the receiver operating …
Predicting Difficult Airway In Morbidly Obese Patients Using Ultrasound, Sevim Akin, Mustafa Yildirim, Hakan Artaş, Esef Bolat
Predicting Difficult Airway In Morbidly Obese Patients Using Ultrasound, Sevim Akin, Mustafa Yildirim, Hakan Artaş, Esef Bolat
Turkish Journal of Medical Sciences
Difficult mask ventilation and difficult intubation are more common in obese patients. Ultrasound is a reliable andnoninvasive method for evaluating the airway. The aim of this study was to investigate the contribution and availability of anterior necksoft tissue (ANS) thickness at different levels, tongue volume (TV), hyomental distance (HMD), the ratio of preepiglottic distance todistance between the epiglottis and the midpoint of vocal cords (PE/E-VC) measured by ultrasonography in predicting difficult airwayin morbidly obese patients.Materials and methods: Between March 2020 and November 2020, patients aged ≥18 years with a body mass index (BMI) of ≥40 kg/m2who underwent elective surgery under …
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Turkish Journal of Medical Sciences
Anemia in the first week after birth, which could affect growth, development, and organ function, should be an important warning sign to clinicians. The aim of this study was to assess the related risk factors of early neonatal anemia and to analyze the effect of anemia on the expression levels of myocardial markers in newborns.Materials and methods: Clinical data from 122 confirmed cases of anemic newborns and 108 nonanemic newborns were collected to analyze the independent risk factors for early anemia using logistic regression analyses. Blood samples were collected from both groups for the detection of myocardial markers, including the …
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Turkish Journal of Medical Sciences
Congenital anomalies of the kidney and urinary tract(CAKUT) are the leading causes of childhood chronic kidney disease (CKD). The etiology of most of the cases is thought to be multifactorial. In this study, risk factors for CAKUT and the effect of mobile phone-related electromagnetic field (EMF) exposure during pregnancy were investigated.Materials and methods: Fifty-seven cases and 57 healthy controls under 2 years of age were included and their mothers were subjected to a questionnaire. Groups were compared for parents’ demographics, pregestational (chronic disease, body mass index, use of the folic acid supplements) and antenatal variables (gestational disease, weight gain during …
Evaluation Of Accompanying Allergic Disease In Children With Proven Drug Allergies, Şule Büyük Yaytokgi̇l, Kezban İpek Demi̇r, Özge Yılmaz Topal, Azize Pınar Metbulut, İlknur Külhaş Çeli̇k, Müge Toyran, Ersoy Ci̇velek, Emine Di̇bek Misirlioğlu
Evaluation Of Accompanying Allergic Disease In Children With Proven Drug Allergies, Şule Büyük Yaytokgi̇l, Kezban İpek Demi̇r, Özge Yılmaz Topal, Azize Pınar Metbulut, İlknur Külhaş Çeli̇k, Müge Toyran, Ersoy Ci̇velek, Emine Di̇bek Misirlioğlu
Turkish Journal of Medical Sciences
Data on the prevalence of allergic diseases in children with proven drug allergies are limited. We aim to evaluate thefrequency of allergic comorbidity in children with proven common drug allergies.Materials and methods: Children with drug hypersensitivity confirmed by diagnostic allergy tests at our center between January 2010and December 2020 were screened retrospectively. Patients with the most common drug allergies (due to antibiotics, nonsteroidalantiinflammatory drugs [NSAIDs], and antiepileptic drugs) were selected for analysis. Age, sex, the culprit drug, initial reactioncharacteristics, diagnostic test results, and the study physician who diagnosed concomitant allergic diseases were noted.Results: A total of 168 patients (boys, 51.2%) …
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Turkish Journal of Medical Sciences
The Canadian Occupational Performance Measure (COPM) is a person-centered assessment tool frequently used to identify occupational problems in older individuals and establish goals for geriatric rehabilitation. This study aims to assess the validity and reliability of the Turkish version of COPM (COPM-TR) in older people.Materials and methods: One hundred older people completed the COPM-TR, and 25 of them participated in a retest within two weeks. The convergent construct validity analyses of the COPM-TR included conducting correlation analyses between the COPM-TR and the Functional Independence Measure (FIM) and Lawton Brody Instrumental Activities of Daily Living (Lawton-IADL) scales. The Performance and Satisfaction …
Letter To The Editor: Serum Amylase On Postoperative Day One Is A Strong Predictor Of Pancreatic Fistula After Pancreaticoduodenectomy: A Retrospective Cohort, Cengiz Ceylan
Turkish Journal of Medical Sciences
No abstract provided.
Assessing Depression, Anxiety, Stress, And Occupational Decision Regret Levels Among Resident Physicians Working At Ankara University Faculty Of Medicine Hospital, Emrah Emi̇ral, Bari̇s Örs, Nergi̇s Cantürk
Assessing Depression, Anxiety, Stress, And Occupational Decision Regret Levels Among Resident Physicians Working At Ankara University Faculty Of Medicine Hospital, Emrah Emi̇ral, Bari̇s Örs, Nergi̇s Cantürk
Turkish Journal of Medical Sciences
Background/aim: Physicians work under high stress levels due to factors such as excessive workload, emotional factors, and economic variables. This situation leads to various health problems such as depression, burnout, fatigue, and hopelessness, resulting in decreased interest in a medical career and an increase in career choice regret. Materials and methods: 300 volunteer resident physicians from Ankara University Medical Faculty Hospital participated in the study. The data for the research was collected using a survey form prepared by reviewing the literature. The survey consisted of three parts, which questioned the physicians' socio-demographic characteristics and professional choices, including the Depression, Anxiety, …
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Turkish Journal of Medical Sciences
Background/aim: Fall risk assessment is crucial for older adults because falls are associated with morbidity and mortality. This study investigated the relationship of gait speed (GS) and handgrip strength (HGS) with falls and assessed whether cognition mediates this causality.Materials and methods: The study was conducted in a tertiary referral geriatric outpatient clinic. The physical performance of participants was evaluated by GS and HGS. All falls the previous year were noted and factors associated with falls were analyzed using multivariate regression analysis.Results: A total of 1,018 older adults, with a mean age of 78.8 years (±7.2), of whom 64.2% were female, …
Braf Inhibitor Candidate Molecule Usnic Acid Might Use Both Intrinsic And Extrinsic Pathways Of Apoptosis, Burcu Peli̇n Buyuk, Demet Cansaran Duman, Turker Duman
Braf Inhibitor Candidate Molecule Usnic Acid Might Use Both Intrinsic And Extrinsic Pathways Of Apoptosis, Burcu Peli̇n Buyuk, Demet Cansaran Duman, Turker Duman
Turkish Journal of Medical Sciences
Background/aim: Melanoma is one of the most aggressive cancers and treatment methods commonly used for patients with skin cancer include checkpoint and BRAF/MEK inhibitors, traditional chemotherapy drugs, radiation and adjuvant treatment methods. Due to the resistance and toxic effects that the patient develops against the drugs, an effective treatment method has not been developed for melanoma yet. Materials and methods: In this study we evaluated the anti-cancer effect of usnic acid (UA) on A-375 melanoma cells and human epidermal melanocytes by xCELLigence real-time cell analysis system. To determine through which cell death pathway UA exerts its anti-proliferative effect, its apoptotic …
Minimally Invasive Sacroiliac Fusion; Current Insights And A Comprehensive Literature Review, Aydin Apaydin, Mehmet Yurtluk, Khoi̇ Than
Minimally Invasive Sacroiliac Fusion; Current Insights And A Comprehensive Literature Review, Aydin Apaydin, Mehmet Yurtluk, Khoi̇ Than
Turkish Journal of Medical Sciences
The sacroiliac joint (SIJ) is an easily dismissable cause of lower back pain (LBP). Recently has gained attention as the source of pain and surgeries addressing this issue have gained attention among surgeons. Classically open fusion surgery was used for the pelvic and sacral fractures to stabilize the structure and then open SIJ fusion surgery started to be used for pain management until the discovery of minimally invasive surgery (MIS). MIS offered fast and effective pain relief with significantly less risk of adverse events following the surgery. Therefore gaining more and more attention each day among surgeons. Our literature review …
Evaluating The Performance Of The Mskcc Gastric Cancer Survıval Calculator In The Turkısh Population, İlknur Deli̇ktaş Onur, Tuğba Başoğlu Tüylü, Nazim Demi̇rcan, Tuğba Akin Telli̇, Ruki̇ye Arikan, Özlem Ercelep, Serdar Turhal, Mehmet Öztürk, Perran Yumuk, Faysal Dane
Evaluating The Performance Of The Mskcc Gastric Cancer Survıval Calculator In The Turkısh Population, İlknur Deli̇ktaş Onur, Tuğba Başoğlu Tüylü, Nazim Demi̇rcan, Tuğba Akin Telli̇, Ruki̇ye Arikan, Özlem Ercelep, Serdar Turhal, Mehmet Öztürk, Perran Yumuk, Faysal Dane
Turkish Journal of Medical Sciences
Bacground/Aim: The MSKCC(Memorial Sloan Kettering Cancer Center) nomogram was developed to predict survivorship in gastric cancer patients undergoing R0 resection. This study aimed to evaluate the predictive power of this nomogram in the Turkish patient population. Materials and Methods: Gastric cancer patients over 18 years of age who were admitted to our clinic between 2000 and 2019 and underwent primary curative surgery and R0 resection were included in the study. The 5-year and 9-year overall survival rates of 489 patients were analyzed. Real-life survival rates and those calculated with the MSKCC tool were compared in all patients and subgroups. The …
Clinicopathological Features For The Prediction Of Immunosuppressive Treatment Responses In Sarcoidosis-Related Kidney Involvement: A Single-Center Retrospective Study, Ahmet Burak Di̇ri̇m, Vafa Suleymanova, Ozge Hurdogan, Özgür Oto, Ayşe Artan, Savas Ozturk, Yasemi̇n Ozluk, Isi̇n Ki̇li̇caslan, Hali̇l Yazi̇ci̇
Clinicopathological Features For The Prediction Of Immunosuppressive Treatment Responses In Sarcoidosis-Related Kidney Involvement: A Single-Center Retrospective Study, Ahmet Burak Di̇ri̇m, Vafa Suleymanova, Ozge Hurdogan, Özgür Oto, Ayşe Artan, Savas Ozturk, Yasemi̇n Ozluk, Isi̇n Ki̇li̇caslan, Hali̇l Yazi̇ci̇
Turkish Journal of Medical Sciences
Background/aim: Sarcoidosis is a multisystem disorder that affects many organs, including the kidneys. This single-center retrospective study investigated the clinical, pathological, and laboratory findings of patients with kidney sarcoidosis who were treated with immunosuppressives.Materials and Methods: Twenty-three patients with biopsy-confirmed kidney sarcoidosis were included. Demographics, clinical, pathological, and laboratory findings, in addition to treatments, and outcomes of twenty patients with at least one month of follow-up were evaluated.Results: Median age at the time of biopsy was 47 years(60.9 % female). Median baseline eGFR and proteinuria were 21.5 ml/min and 1 g/g or g/day, respectively. Nineteen of the 23 patients were …
Evaluation Of The Association Of Mucosa-Associated Invariant T (Mait) Cells With Childhood Asthma, Meral Ekşi̇, Huri̇ Bulut, Erdem Akalin, Feyza Ustabaş Kahraman, Hakan Yazan, Mebrure Yazici, Mustafa Nursoy, Emi̇n Özkaya, Abdürrahi̇m Koçyi̇ği̇t, Erkan Çakir
Evaluation Of The Association Of Mucosa-Associated Invariant T (Mait) Cells With Childhood Asthma, Meral Ekşi̇, Huri̇ Bulut, Erdem Akalin, Feyza Ustabaş Kahraman, Hakan Yazan, Mebrure Yazici, Mustafa Nursoy, Emi̇n Özkaya, Abdürrahi̇m Koçyi̇ği̇t, Erkan Çakir
Turkish Journal of Medical Sciences
Background/aim: Innate-like T lymphocytes are a recently defined group of T cells comprising mainly mucosa-associated invariant T (MAIT) cells. The relationship between MAIT cells and childhood asthma is controversial. In this study, we aimed to determine the role of MAIT cells in patients with allergic asthma (AA) and nonallergic asthma (NAA). This is the first study to compare the ratios of these cells in patients with AA and NAA.Materials and methods: The study included children aged 6–18 years with AA (n = 41) or NAA (n = 30) and healthy control subjects (n = 36). The control group consisted of …
Comparison Of Classical Methods For Bone Age Determination With Capitohamate Planimetry On Wrist X-Rays, Hasan Yildiz, Nadi̇re Ünver Doğan, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Muslu Körez, Ahmet Karabulut
Comparison Of Classical Methods For Bone Age Determination With Capitohamate Planimetry On Wrist X-Rays, Hasan Yildiz, Nadi̇re Ünver Doğan, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Muslu Körez, Ahmet Karabulut
Turkish Journal of Medical Sciences
Background/aim: This study aims to compare the Greulich–Pyle (GP) and Tanner–Whitehouse 2 (TW2) methods, both used in left wrist radiography for bone age determination in the pediatric age group, with the Capitohamatum method (CH) due to the importance of determining bone age in the pediatric period.Materials and methods: Direct radiographs of 210 female and 291 male individuals between the ages of 0–15 without any pathology in the left wrist bones were obtained; 501 os capitatum and os hamatum on anterior-to-posterior direct graphic images were measured using the GP, TW2, and CH planimetry methods. The estimated age of each measurement was …
Severe Degranulation Of Mesenteric Mast Cells In An Experimental Rat Mammary Tumor Model, Senem Yavaş, Özkan Yavaş, Semi̇ha Ersoy, Gürsel Sönmez
Severe Degranulation Of Mesenteric Mast Cells In An Experimental Rat Mammary Tumor Model, Senem Yavaş, Özkan Yavaş, Semi̇ha Ersoy, Gürsel Sönmez
Turkish Journal of Medical Sciences
Background/aim: Breast cancers are one of the most common cancers in women and are responsible for many deaths worldwide. Mast cells are inflammatory cells. Their role in cancers is controversial, and there is limited data on systemic mast cell activation in cancer cases. This study aimed to evaluate systemic mast cell activation in an experimentally induced rat model of breast cancer. Materials and methods: Sprague Dawley female rats were divided into control (n=6) and mammary tumor (n=12) groups. In the tumor group, 20 mg 12-dimethylbenz[a]anthracene (DMBA) dissolved in 1 ml cottonseed oil was administered intragastrically by gavage, and the rats …
In Silico Study Of Bioactive Compounds Derived From Indonesian Marine Invertebrates As Novel Antituberculosis Agent, Ayu Masyita, Eri̇s Septiana, Asep Bayu, Bustanussalam Bustanussalam, Jonathan A. Panggabean, Fi̇rdayani̇ Firdayani, Tuti̇k Murniasih
In Silico Study Of Bioactive Compounds Derived From Indonesian Marine Invertebrates As Novel Antituberculosis Agent, Ayu Masyita, Eri̇s Septiana, Asep Bayu, Bustanussalam Bustanussalam, Jonathan A. Panggabean, Fi̇rdayani̇ Firdayani, Tuti̇k Murniasih
Turkish Journal of Medical Sciences
Background/aim: Tuberculosis has still become the most deadly disease globally. The problem of finding an effective therapeutic is one of the obstacles in the treatment of patients. Marine invertebrates were a treasure since they produced many active compounds. Following up on this issue, screening active compounds is very important. This study will explain the result of anti-tuberculosis screening of compounds derived from marine invertebrates using in silico and confirmed to the in vitro-data.Materials and methods: Three-dimensional (3D) structures of pantothenate kinase (MtPanK type 1, PDB ID: 4BFT), Mycobacterium tuberculosis InhA (MtInhA, PDB ID: 2X23), protein kinase B (PDB ID: 5U94), …
Epidemiology Of Heart Failure In Türkiye, Nai̇m Ata, İnci̇ Tuğçe Çöllüoğlu, Anil Şahi̇n, Mehmet Bi̇rhan Yilmaz, Sanem Nalbantgi̇l, Şuayi̇p Bi̇ri̇nci̇, Mustafa Mahi̇r Ülgü, Emi̇ne Arzu Kanik, Di̇lek Ural, Lale Di̇nç Asarcikli, Emre Demi̇r, Yüksel Çavuşoğlu, Selda Murat, Ahmet Çeli̇k
Epidemiology Of Heart Failure In Türkiye, Nai̇m Ata, İnci̇ Tuğçe Çöllüoğlu, Anil Şahi̇n, Mehmet Bi̇rhan Yilmaz, Sanem Nalbantgi̇l, Şuayi̇p Bi̇ri̇nci̇, Mustafa Mahi̇r Ülgü, Emi̇ne Arzu Kanik, Di̇lek Ural, Lale Di̇nç Asarcikli, Emre Demi̇r, Yüksel Çavuşoğlu, Selda Murat, Ahmet Çeli̇k
Turkish Journal of Medical Sciences
Background/aim:The epidemiological data on heart failure (HF) vary between regions within the same country.We aimed to investigate the epidemiological data on HF in Turkiye across all age groups regarding seven geographical regions.Materials and methods:We included all patients in the Turkish population with a first diagnosis of HF between January 1, 2016 and December, 31 2022, with the use of ICD-10 codes from the National Electronic Healthcare Database.The data were categorized by seven geographical regions of Turkiye.Results:The median age of index diagnosis of HF was 70(60-78) years in all age groups and 4(1-12) years in pediatric population.Prevalence rate of HF was …
Association Between Glucagon-Like Peptide-1 Receptor Agonists Use And Change In Alcohol Consumption: A Systematic Review, Mohsan Subhani, Ashwin Dhanda, James A. King, Fiona C. Warren, Siobhan Creanor, Melanie J. Davies, Sally Eldeghaidy, Stephen Bawden, Penny A. Gowland, Ramon Bataller, Justin Greenwood, Stephen Kaar, Neeraj Bhala, Guruprasad P. Aithal
Association Between Glucagon-Like Peptide-1 Receptor Agonists Use And Change In Alcohol Consumption: A Systematic Review, Mohsan Subhani, Ashwin Dhanda, James A. King, Fiona C. Warren, Siobhan Creanor, Melanie J. Davies, Sally Eldeghaidy, Stephen Bawden, Penny A. Gowland, Ramon Bataller, Justin Greenwood, Stephen Kaar, Neeraj Bhala, Guruprasad P. Aithal
Peninsula Medical School
Background: Despite the availability of various pharmacological and behavioural interventions, alcohol-related mortality is rising. This systematic review aimed to critically evaluate the existing literature on the association between glucagon-like peptide-1 receptor agonists use (GLP-1 RAs) and alcohol consumption. Methods: Electronic searches were conducted on Ovid Medline, EMBASE, PsycINFO, clintrials.gov, and ProQuest until the end of March 2024. An updated search was done on 7th of August 2024. The primary outcome was to explore the association between GLP-1 RAs use and change in alcohol consumption. Secondary outcomes included evaluating the impact of GLP-1 RAs on occurrences of alcohol-related events, healthcare utilisation, …