Digital Commons Network^™

Preexisting Conditionings: Painting, Gaming And Narrative Play, Pia Bakala

Theses and Dissertations

My work incorporates play, fantasy, and self-actualization through painting, sculpture, and video. In this essay, I will explore the ways in which my studio practice intersects with topics across fields of visual arts and in conjunction their theoretical frameworks. I will discuss the culminating body of work, tentatively titled Preexisting Conditionings, that my academic experience at VCU has fostered and trace its development across specific precursive works, as well as the cultural and intellectual touchstones influencing its creative impetus. In Preexisting Conditionings, I work primarily use oil painting, creating mostly representational figurative tableaus that correspond to narratives and characters I’m …

Mindfulness, Moral Outrage, And The Climate Crisis: A Novel Approach Toward Motivating Pro-Environmental Behaviors, Erika Blair

Theses and Dissertations

The consequences of anthropogenic climate change are severe, continuously accelerating, and pose serious threats to the human and natural world. It is imperative to address the climate crisis from a psychosocial perspective and incite lasting, individual-level behavioral change. Various theoretical models have been adapted or developed to explain pro-environmental behaviors. However, the predictive powers of the most commonly used models have proven to be limited, and the underlying psychological processes of pro-environmental behavior constitute a significant gap in the literature. The present study identifies two psychological processes that show significant promise in motivating pro-environmental behaviors: moral outrage and mindfulness. Moral …

Mathematical Modeling Of Phage-Bacteria Population Dynamics, John Lawrence D. Palacios

Theses and Dissertations

Bacteriophages are viruses that infect and replicate within bacteria. Lytic phages cause the bacterial cell to burst, killing the bacteria. These types of phages can be used to treat patients with antibiotic-resistant bacterial infections. As a step in developing successful treatment protocols, we aim to understand the population dynamics of phages and bacteria using an in vitro model. We model the dynamics using the Campbell model, which consists of a delay differential equation (DDE), as a base model. We extended the model by including the emergence of phage resistance. We then compared the DDE model with a parallel ordinary differential …

Impact Of Genetic Polymorphism On Pulmonary Function And Individualized Treatment Plan In Pulmonary Tuberculosis, Hayder Ghali Wadi Algawwam, Affan Ezzat Hasan

Hilla University College Journal For Medical Science

Background: Less than 10% of people infected with M. tuberculosis develop the disease, suggesting that there are individual differences in susceptibility to tuberculosis. Defective genes could impact the host's immune response toward any infection, including pulmonary TB. Numerous genetic risk loci like HLA-G, MMP-1, IFN-γ, TLR-2, MCP-1, NRAMP-1 and many others have been discovered by recent genome-wide association studies, which indicate a high polygenic heritability for tuberculosis.

Aim: The aim of this review is to shed light on the potential effect of host genetic polymorphism on the degree of impairment in pulmonary function tests in individuals with pulmonary tuberculosis.

Conclusion: …

Contrast-Associated Nephropathy: A Comprehensive Review, Karam Akram Al- Akkam, Mufeed Jalil Ewadh, Shukry Faez Al-Saad

Hilla University College Journal For Medical Science

Acute renal failure can be attributed to Contrast-Associated Nephropathy (CAN), which remains a threat due to population variation and the increasing use of contrast media in various techniques. Thus, this review aims to discuss the pathophysiology, factors and risk factors for CAN, measures for prevention, and approaches to its management. The pathophysiology of CAN is extensive and encompasses various factors. Vasoconstriction and medullary hypoxia in the renovascular bed area are crucial in the pathogenesis of CAN. Several contrast media can provoke the formation of free radicals and reactive oxygen species (ROS), leading to oxidative stress, an inflammatory response, and enhancing …

Applications Of Shape Analysis, Yang Zhang

Graduate Research Theses & Dissertations

Shape analysis is a field of Statistics focused on analyzing and understanding the shape or the geometric properties of objects. We utilize the Bayesian circular cubic smoothing splines to estimate the shapes and introduce a rotation-based alignment method. A simulation study investigates the effect of shape alignment. As an application, we estimate the shapes of hourly crime rates in urban centers across the United States and compare the aligned shapes for different types and locations of crimes. In addition, we apply the proposed shape estimation with alignment to the survival analysis for the length of hospitalization of COVID-19 patients in …

Essays On Computational And Financial Economics, Mohammadreza Mahmoudi

Graduate Research Theses & Dissertations

This dissertation comprises three essays centered on computational and financial economics, addressing the economic implications of the COVID-19 pandemic, the interplay between monetary policy and the cryptocurrency market, and the strategies for cryptocurrency portfolio optimization.

In the first essay, the spotlight is cast on the U.S. government's response to the COVID-19 pandemic and its subsequent economic ramifications. The study meticulously assesses the implemented uniform pandemic control policies and contrasts them with potential targeted measures. These targeted strategies take into account the differential effects of the virus on various age demographics. By employing the adjusted SEQIHR model as a tool for …

Molecular Investigation Of Tick-Borne Pathogens In Feral Swine (Sus Scrofa) From Seven Us States, Sofiane Aiche

Masters Theses

Feral swine (Sus scrofa) have been proposed as part of the lifecycles of multiple tickborne pathogens (TBP). This is a result of the increase in feral swine populations and increased tick populations and geographic ranges. Few surveys exist on the TBP relevant to human and wildlife of feral swine in the US. The aim of this study is to investigate the prevalence of 10 TBP: Anaplasma spp., Borrelia spp., Cytauxzoon felis, Hepatozoon spp., Babesia spp., Mycoplasma spp., Trypanosoma cruzi, Toxoplasma gondii, Yersinia pestis, and Rickettsia spp. A total of 87 feral swine blood samples …

Regulatory Approval Of Clinical Trials: Is It Time To Reinvent The Wheel?, Mansoor Saleh, Karishma Sharma, Aisleen Shamshudin, Innocent Abayo, Stacey Gondi, Noureen Karimi

Haematology and Oncology, East Africa

Less than 1% of all clinical trials are conducted in Africa. In 2019, only six of 26 oncology clinical trials conducted in Africa were conducted in countries with subjects of African ancestry. There are multiple barriers that hinder the conduct of cancer clinical trials in Africa. Time to trial activation (TTA) is the administrative and regulatory process required before a study can be activated—an important metric and often a major barrier for site selection. In Kenya, TTA involves review by Institutional Review Board (IRB), Pharmacy and Poisons Board, National Commission for Science, Technology and Innovation and Ministry of Health, all …

Biographical Feature: Charles Y. Chiu, M.D., Ph.D., Erik Munson

Clinical Lab Sciences Faculty Research and Publications

No abstract provided.

The Association Between Disease Burden And Alzheimer's Hospitalization Rates In Older Adults., Autumn Johnson

High Impact Practices Student Showcase Spring 2025

Dementia refers to symptoms that impair daily life, including social and intellectual abilities, with memory loss being a key feature. Conditions such as Creutzfeldt-Jakob Disease, Huntington’s Disease, and Alzheimer’s Disease (AD) are major causes of memory loss. Alzheimer’s is a progressive disorder that deteriorates memory and thinking skills, characterized by withdrawal from social activities, mood changes, and confusion about time or place.

Age is the leading risk factor for Alzheimer’s, alongside non-modifiable factors like genetics and family history. Modifiable factors include physical activity, smoking, education, and social engagement. The Alzheimer’s Association’s 2024 fact sheet emphasizes the need for more research …

The Effect Of Covid-19 Lockdown On Traffic Crashes In Texas., Hatim Sharif, Samer Dessouky

Publications

An analysis of traffic patterns during COVID-19 has identified that reduction in the miles traveled has a significant negative correlation with COVID-19 cases and deaths across the USA. Preliminary statistics in the US suggest an increase in fatal crashes over the period of the lockdown in comparison to the same period in previous years. Moreover, while total crashes are down, motor vehicle crashes involving non-motorists became more prevalent. At the same time, non-motorist traffic has increased while motor vehicle traffic and crashes have shifted to the local systems. The main goal of this research is to perform a comprehensive evaluation …

A Closer Look At Denali’S Alpine Wildlife: Assessing The Influences Of Climate And Vegetation Changes On Species In Alaska, Jennifer Lynn Wall

Graduate Student Theses, Dissertations, & Professional Papers

Climate change is amplified in polar regions and could have considerable consequences for biodiversity. Arctic and boreal regions, in particular, have warmed more than double the global average and are experiencing increasing precipitation, thawing permafrost, shrinking snow seasons, and increasing shrub- and tree-line encroachment. These changes are suspected to influence key alpine biodiversity, including species such as collared pikas (Ochotona collaris), hoary marmots (Marmota caligata), and Arctic ground squirrels (Urocitellus parryii). But, we have limited understanding of whether this is true and, if so, which factors drive distributional shifts in response to climate change. For this dissertation, I collected data …

Understanding Disparities In Hypertension Treatment Cascade And Validating Blood Pressure Measurement Among Persons Living With Or At Risk For Hiv, Jessica Blair

All ETDs from UAB

In the United States, 44% of adult women >18 years have hypertension. Although non-Hispanic Black adults were more likely to be aware of and treated for hypertension compared to non-Hispanic White adults, Black individuals had the highest prevalence of uncontrolled hypertension. Persons living with HIV have a higher prevalence of hypertension, which is a major modifiable risk factor for cardiovascular disease. Similar to the geographic distribution of hypertension in the US, people living in the South have higher incidence of both hypertension and HIV diagnoses compared to other US regions. Furthermore, accurate diagnosis of hypertension and initiation of treatment is …

Translocations Of North American Bison Across Large Climatic Gradients: Impacts On Thermoregulation, Body Size, And Helmintic Infection, Hayden Wolfe

Electronic Theses and Dissertations

Every year, one-eighth of all North American bison (Bison bison) are translocated, often across large climatic gradients. Over the last 16 years bison have been translocated from Wind Cave National Park in South Dakota to establish six herds across the United States central grasslands in Iowa, Missouri, Illinois, Indiana, and Kansas. Influence of climatic gradients on herd-level thermoregulation, body size, and helmintic infection were evaluated. Overall, 1174 thermal images and 1050 fecal samples were collected between 2021 and 2023. Physiological heat flux was used to measure thermoregulation, asymptotic body mass (ABM) was used for body size, and helminth genera abundance …

State Of The Science Of Scale-Up Of Cancer Prevention And Early Detection Interventions In Low- And Middle-Income Countries: A Scoping Review, Tara M Friebel-Klingner, Gloria Guevara Alvarez, Hope Lappen, Lydia E Pace, Keng-Yen Huang, Maria E Fernández, Donna Shelley, Anne F Rositch

Faculty, Staff and Student Publications

Purpose: Cancer deaths in low- and middle-income countries (LMICs) will nearly double by 2040. Available evidence-based interventions (EBIs) for cancer prevention and early detection can reduce cancer-related mortality, yet there is a lack of evidence on effectively scaling these EBIs in LMIC settings.

Methods: We conducted a scoping review to identify published literature from six databases between 2012 and 2022 that described efforts for scaling cancer prevention and early detection EBIs in LMICs. Included studies met one of two definitions of scale-up: (1) deliberate efforts to increase the impact of effective intervention to benefit more people or (2) an intervention …

Zooming In On A Snapshot Of Care: Adapting The Index Of Care For Historical And Modern Individuals In The Terry Collection, Felicia Robyn Sparozic

Graduate Student Theses, Dissertations, & Professional Papers

This dissertation adapts the Index of Care (IOC), traditionally focused on prehistoric contexts, to historical (1840-1950) and modern (post-1950) individuals from the Smithsonian’s Terry Collection, to account for those individuals with extensive records. By introducing sister methodologies for both historical and modern contexts, this research bridges the methodological gap in care analysis, enhancing the original IOC with contextual environmental variables and, for modern individuals, DNA analysis.

The study utilizes a selected cohort from the Terry Collection, emphasizing the investigation of caregiving practices across different sexes and ancestral backgrounds. Contrary to initial hypotheses predicting sex-based differences in care provision, findings show …

The Blackfeet Nation’S Bison Conservation Herd Management Plan, Brandon Kittson

Graduate Student Theses, Dissertations, & Professional Papers

This document is meant to act as a guide to understanding Bison reintroduction on the Blackfeet reservation and serve as a resource for bison management. This report and plan will: 1) review bison ecology and the history of reintroduction efforts on the reservation; 2) identify potential issues and barriers to successful reintroduction; 3) present a summary of current land policies and patterns of land use on the reservation; and 4) provide recommendations for dealing with those potential issues. Recommendations will be based on analyses of previous knowledge of bison and bison behavior.

An Endemic Issue: Malawi's Struggle To Prevent Childhood Malaria, Hailey A. Smalley

Graduate Student Theses, Dissertations, & Professional Papers

Malaria is one of the most prolific diseases in the world, generating hundreds of millions of cases and hundreds of thousands of deaths a year. In 2021, the World Health Organization initiated preliminary trials for the first malaria vaccine in three countries, including Malawi. This project explores the impact of the malaria vaccine on community perspectives and health outcomes related to malaria , describes ongoing challenges that health workers face when disseminating the vaccine, and explains how Malawi’s experience implementing the malaria vaccine reflects larger trends in international aid.

Perspectives Of Utilizing Pharmacogenomics To Inform Tobacco Cessation: Survey Results From An American Indian Community, Madeline Lousie Davies

Graduate Student Theses, Dissertations, & Professional Papers

Pharmacogenomics research has predominantly focused on populations of European ancestry, limiting the application for diverse populations such as American Indian and Alaska Native (AIAN) communities. Our community-centric study aims to understand perspectives of utilizing pharmacogenomics to guide tobacco cessation in an AIAN community using a survey with qualitative and quantitative components. We assessed participant (n=273) tobacco usage and cessation history, pharmacogenomics knowledge, and perceptions of utilizing pharmacogenomics in the context of tobacco cessation. We found that the majority of participants (92%) were aware of risks associated with tobacco usage and believe it to be a problem within their community (76%). …

Cultural Matching And Identity Safety In K-12 Schools: An Indigenous Research Paradigm, Ashton T. Smith

Graduate Student Theses, Dissertations, & Professional Papers

Native American and Alaska Native (NA/AN) persons are resilient and have learned to overcome the intergenerational effects of colonization and find new ways to be Native American and Alaska Native in this contemporary life. Learning and well-being are integral values for Native American and Alaska Native people, but finding an appropriate way to approach education and learning can be difficult for Native American and Alaska Native people, especially when historically, the colonial-based systems have been created for them to fail. Because cultural matching and identity safety (CM/IS) for Native American and Alaska Native people in other environments (e.g., psychotherapy, child-welfare …

Under The Influence: Pf Bacteriophage Modulate Pseudomonas Aeruginosa Virulence & Pathogenesis, Amelia Kass Schmidt

Graduate Student Theses, Dissertations, & Professional Papers

Pseudomonas aeruginosa is a gram-negative opportunistic bacterial pathogen which is as ubiquitous in the natural environment as it is within hospital settings, where it is a readily acquired nosocomial pathogen. Bacteriophages, viruses which infect bacteria, are a central component of the arsenal P. aeruginosa leverages to combat the stresses of infecting mammalian hosts. Over 60% of P. aeruginosa clinical isolates are chronically infected with temperate phages within the family of Inoviridae. These phages, referred to as Pf, have a filamentous virion structure which accommodates genome sizes between 10-20kbp. Pf is capable of integration into the bacterial chromosome where they can …

Evaluation Of The Diagnostic Performance Of Nucleocapsid Antigen For Severe Acute Respiratory Syndrome Coronavirus 2 Infection, Doaa Fathy Ahmed, Amal Ahmed Mohamed, Manar S. Fouda, Sara A. Mekkawy, Randa Ibrahim Ahmed, Omar Mohamoud Azzam, Doaa Ghaith, Ahmed El-Kasses, Mostafa Omran

Trends in advanced sciences and technology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) was identified as the aetiological agent of coronavirus disease 2019 (COVID-19). The SARS-COV-2 genome encodes four structural proteins include spike (S) protein, envelope (E) protein, membrane (M) protein, and nucleocapsid (N) protein. nucleocapsid protein is one of the predominantly expressed structural proteins and has been confirmed as an ideal target for early diagnostic detection in SARS-COV-2 infection. In the current study, the diagnostic performance of Nucleocapsid antigen in severe acute respiratory syndrome Coronavirus 2 infected individuals is evaluated in Egypt. Patients and Methods: All human individuals’ samples (n= 106) were collected from El …

How Can We Do Better? Understanding Student Experiences And Support Needs During And After The Covid-19 Pandemic, Kevina M. Brown

Dissertations

This dissertation study aimed to provide opportunities for students at San José State University (SJSU), to share about their experiences during the Covid-19 pandemic and to provide feedback and recommendations regarding resources and culturally engaging supports on campus. The research inquiry involved survey and interview methodology to gain insights into student experiences pertaining to financial and mental health challenges and academic disruption and social isolation during the beginning, middle and end of the pandemic, as well as their engagement with resources and supports provided on campus. Recruitment was done by flyer distribution throughout campus and via email distribution to students …

Global Perspectives On Healthcare Waste Management And Bibliographic Mapping During The Crises Of Covid-19, Vasudeo Zambare, Bhushan Bhusare, Lew Christopher, Mohanadoss Ponraj, Nabin Narayan Munankarmi, Mohd Fadhil Md. Din

Applied Environmental Research

The lack of proper waste management of health care facilities can have a significant negative health impact on the global population. This study provides a critical view on the current state of the existing healthcare waste management practices used in healthcare facilities around the world during the Coronavirus disease 2019 (COVID-19) pandemic outbreak. The increasing amount of COVID-related healthcare waste was analyzed and classified to provide justification for the urgent need to develop waste management standards that ensure safe containment and diversion of hazardous and non-hazardous wastes through recycling, reuse and repurposing. The waste handling, treatment, and disposal management of …

Investigating The Mechanisms For Priming And Maintaining Tumor Ag Specific Cd8+ T Cell Responses In The Context Of Cd4-Depletion, Delaney E. Ramirez

Dartmouth College Ph.D Dissertations

Achieving durable, systemic CD8+ T cell responses against tumors is an imperative goal in treating cancer. However, suppressive cells, including Foxp3+CD4+ regulatory T cells (Tregs) are widely recognized to inhibit CD8+ T cell activity. For nearly two decades, anti-CD4 treatment has been used to eliminate Tregs and induces durable tumor antigen (Ag) specific CD8+ T cells, despite also depleting Foxp3-negative conventional CD4+ T (Tconv) cells. However, the underlying mechanism of anti-CD4 efficacy is not understood. In Chapter Three, we look beyond Treg depletion and investigate the potential contributions of other factors including homeostatic space, depletion of CD4+ APCs, and presence …

2024 Community-Based Care. Resident And Community Characteristics Report On Assisted Living, Residential Care, And Memory Care Communities, Ozcan Tunalilar, Sarah Dys, Yuliana Levchenko, Diana Jacoby, Minju Kim, Wafi Albalawi, Paula Carder

Institute on Aging Publications

This report marks the 10th anniversary of the Resident and Community Characteristics Report on Assisted Living (AL), Residential Care (RC), and Memory Care (MC) Communities as part of the Oregon Community Based Care project. This study includes rotating questions that focus on emerging areas of interest in the AL/RC/MC settings based on feedback from ODHS and interested parties alongside a core set of questions that are asked every year or every other year to allow comparisons over time. In this year’s study, we included information about various resident, community, and staff characteristics, including:

• Residents: sociodemographic characteristics (e.g., age, sex, …

Perceptions Of The Covid-19 Vaccination Within A Convenience Sample Of Sudanese Americans, Jonathan Freese, Fatima Abuzaid Mbbs, Mujtaba Abdellatif Md, Harlan Sayles, Nada Fadul

EMET Projects

No abstract provided.

Challenging Medicine: Ivermectin Cases, Medical Futility Cases And The Patient-Physician Relationship, Janet L. Dolgin

Hofstra Law Faculty Scholarship

No abstract provided.

Predictive Power Of Wastewater For Nowcasting Infectious Disease Transmission: A Retrospective Case Study Of Five Sewershed Areas In Louisville, Kentucky., Fayette Klaassen, Rochelle H. Holm, Ted Smith, Ted Cohen, Aruni Bhatnagar, Nicolas A. Menzies

Faculty and Staff Scholarship

Background: Epidemiological nowcasting traditionally relies on count surveillance data. The availability and quality of such count data may vary over time, limiting representation of true infections. Wastewater data correlates with traditional surveillance data and may provide additional value for nowcasting disease trends. Methods: We obtained SARS-CoV-2 case, death, wastewater, and serosurvey data for Jefferson County, Kentucky (USA), between August 2020 and March 2021, and parameterized an existing nowcasting model using combinations of these data. We assessed the predictive performance and variability at the sewershed level and compared the effects of adding or replacing wastewater data to case and death reports. …