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Hist 213-004: 20th Century World, Elektra Kostopoulou

History Syllabi

No abstract provided.

Teaching Procedural Skills: Integrating Educational Theory Into Practice, Christopher J. Smith, Cory Rohlfsen, Jana L. Wardian, Khalid Sahak

Journal Articles: Hospital Medicine

Introduction: Teaching procedural skills is an essential part of health professions education, yet formal training is often lacking from traditional curricula.

Methods: A workshop on teaching procedural skills was developed as part of a clinician educator track at a large health professions university. Participants included medical residents and fellows (postgraduate years 2-6) from various training programs. The 90-minute, interactive training integrated Gagne's model of instructional design with evidence-based teaching practices. Workshop outcomes were evaluated with pre- and postworkshop surveys. Learner reactions (Kirkpatrick level 1) were assessed via course evaluation. Learning and behavior (Kirkpatrick level 2) were evaluated via attitudinal and …

Characterization Of The Interaction Of Three Domains Of Nlrp2 (Pyd, Lrr, And Nacht) With Ebp1 Protein, Rakshya Bhatta

Graduate Theses/Dissertations

NOD-like receptors (NLRs) are cytoplasmic proteins essential for various immune responses such as reactions to infectious diseases, metabolic and cellular damage, fetal development, and cancer. Among the 22 identified NLR proteins, research has highlighted the significant roles of NLRP2 in fetal development. NLRP2 is also classified as a maternal effect gene and the mutation to this gene can lead to DNA methylation imprinting defects, altered gene expression, and conditions such as recurrent miscarriages (RMs). The protein EBP1, which has been found to have roles in embryonic development has been implicated in the regulation of DNA methylation. Recent studies have also …

Temporal Distribution Of Potential Waterborne Pathogens In Sequiota Spring, William J. Durstock

Graduate Theses/Dissertations

Waterborne pathogens from human fecal matter pose a significant health risk in karst environments, where domestic wastewater can easily be transferred to the shallow groundwater system via old, leaky septic tanks and damaged sewer lines. This study monitored fecal indicator bacteria (FIB) and potential pathogens in Sequiota Spring located in the karst region of southwest Missouri, using Microbial Source Tracking (MST) and Illumina DNA sequencing of bacterial 16S rRNA genes. MST identified high levels of human fecal indicator bacteria (HFIB) (up to 110,000 cells/L) in July 2020. By June 2022, HFIB levels had dropped significantly (55-fold reduction) after the City …

Clinical Outcomes Associated With Mrsa Naat Utilization., Shannon B. Leighton, Pharmd, Emily Fox, Greg Tallman

Books, Presentations, Posters, Etc.

Abstract: A recent analysis by the Oregon Regional Antimicrobial Stewardship Program demonstrated that across the Oregon region, MRSA NAAT from the nares have a high negative predictive value (NPV) of 99.4%. These findings were consistent when stratified by culture site. The high NPV suggests that MRSA NAAT nasal swabs can be useful in promoting de-escalation (e.g., discontinuation) of anti-MRSA treatment. Few studies have evaluated if use of the MRSA NAAT influences anti-MRSA treatment de-escalation, and even fewer have assessed important clinical outcomes related to MRSA NAAT utilization and de-escalation. The goal of this study is to evaluate the frequency of …

Unified Resource Browser: An Interactive And Reconfigurable Web Framework For Biomedical Metadata Exploration, Visualization, And Management, Shiwei Lin, Ling Tong, Kimberly A Smith, Lydia Ng, Tyler Mollenkopf, Yan Huang, Rashmie Abeysinghe, Wei-Chun Chou, Antarr T Byrd, Licong Cui, Guo-Qiang Zhang, Xiaojin Li, Shiqiang Tao

Faculty, Staff and Student Publications

We present Unified Resource Browser, a web-based framework designed to optimize the configuration, exploration, visualization, and dissemination of complex biomedical metadata. As a core component of Neuroanatomy-Anchored Information Management Platform (NIMP), Unified Resource Browser enables researchers to efficiently access donor information, brain tissue samples, and sequencing data through structured resource tables and advanced search and filtering capabilities. The platform allows users to customize data views, share configurations via direct links, and seamlessly export data for further analysis. Integrated visualization tools offer immediate insights through customizable charts, enhancing data interpretation. By improving the accessibility and usability of biomedical data resources, Unified …

Not Just A Biblical Disease: Hansen’S Disease (Leprosy) Oregon’S Unique Differential, Zach Taylor, Justin Jin, Andrea Roast, Amy Dechet

Books, Presentations, Posters, Etc.

Background: Hansen’s disease (leprosy) is caused by a gram-positive, acid-fast bacilli called Mycobacterium leprae. It is very slow growing and has an indolent disease process. The disease is more prevalent in underdeveloped countries with poor access to care including Brazil, India, sub-Saharan Africa, and the Pacific Islands including Micronesia and the Philippines. However, it is becoming in creasingly common in the United States, specifically in areas with high levels of immigration from Micronesia. Case: Our patient was a 35-year-old Micronesian man who presented with 7 days of non-traumatic right hand pain with progressive swelling. He migrated to US from Micronesia …

Don’T Poke The Bear: Pheochromocytoma Unmasked By Covid-10, Taylor Virtue, Andrea Roast

Books, Presentations, Posters, Etc.

Introduction: Pheochromocytomas are tumors of the adrenal gland which produce excess catecholamines. The classic clinical triad is paroxysmal headache, diaphoresis, and tachycardia. The rare incidence makes this a challenging diagnosis which is even more challenging in the environment of the COVID-19 pandemic. Case Presentation: Setting: Establishing care visit at a primary care office Demographic: 42 year old male Medical history: Previously well-controlled hypertension, prediabetes HPI: • Weeks of profound, persistent fatigue and lightheadedness after the resolution of acute symptoms (fever, chills) from COVID-19 infection. Denies any headaches or palpitations. • Meticulously measuring vital signs at home. He has noticed that …

Assessing The Utility Of Breast Cancer Polygenic Risk Scores And Association With Clinical Factors In A Population Of Breast Cancer Patients, John L. Slunecka

Dissertations and Theses

INTRODUCTION: Breast cancer (BC) is the most common cancer among women and is classified as a complex disease. Advances in population genomics have led to the development of polygenic risk scores (PRSs) with the potential to enhance current risk models, but replication is often limited. OBJECTIVE: We sought to assess the predictive capabilities of two high-powered BC PRSs in a sample population selected for breast cancer. In addition, the capacity of the PRSs to predict clinical variables that could improve BC screening and treatments was explored. METHODS: Two published PRS algorithms (313 vs 3820) were used to score female subjects …

Korean: 패혈증 알아야 할 사항 - Sepsis What You Need To Know, Providence

All Sepsis Education Materials

패혈증 알아야 할 사항 SEPSIS What You Need to Know (Korean Language)

Chinese-Simplified: 败血症须知事项 - Sepsis What You Need To Know, Providence

All Sepsis Education Materials

败血症须知事项 SEPSIS What You Need to Know (Chinese-Simplified Language)

Armenian: Սեպսիս Ինչ Պետք Է Իմանաք - Sepsis What You Need To Know, Providence

All Sepsis Education Materials

ՍԵՊՍԻՍ Ինչ պետք է իմանաք SEPSIS What You Need to Know (Armenian Language)

Arabic: متالزمة االستجابة االلتهابية الجهازية ما تحتاج إىل معرفته تحتاج إىل معرفته - Sepsis What You Need To Know, Providence

All Sepsis Education Materials

متالزمة االستجابة االلتهابية الجهازية ما تحتاج إىل معرفته SEPSIS What You Need to Know (Arabic Language)

Farsi: Understanding Your Sepsis Diagnosis, Providence

All Sepsis Education Materials

Graphic Novel: Understanding Your Sepsis Diagnosis (Farsi)

Multiomics Analysis To Explore Blood Metabolite Biomarkers In An Alzheimer’S Disease Neuroimaging Initiative Cohort, Takaki Oka, Yuki Matsuzawa, Momoka Tsuneyoshi, Yoshitaka Nakamura, Ken Aoshima, Hiroshi Tsugawa, Alzheimer’S Disease Metabolomics Consortium

Neurology Faculty Publications

Alzheimer’s disease (AD) is a neurodegenerative disease that commonly causes dementia. Identifying biomarkers for the early detection of AD is an emerging need, as brain dysfunction begins two decades before the onset of clinical symptoms. To this end, we reanalyzed untargeted metabolomic mass spectrometry data from 905 patients enrolled in the AD Neuroimaging Initiative (ADNI) cohort using MS-DIAL, with 1,304,633 spectra of 39,108 unique biomolecules. Metabolic profiles of 93 hydrophilic metabolites were determined. Additionally, we integrated targeted lipidomic data (4873 samples from 1524 patients) to explore candidate biomarkers for predicting progressive mild cognitive impairment (pMCI) in patients diagnosed with AD …

Prevalence Of Non-Communicable Diseases Among Household Contacts Of People With Tuberculosis: A Systematic Review And Individual Participant Data Meta-Analysis, Yohhei Hamada, Matteo Quartagno, Farihah Malik, Keolebogile Ntshamane, Anna Tisler, Sanjay Gaikwad, Carlos Acuna-Villaorduna, Perumal Kannabiran Bhavani, Bachti Alisjahbana, Katharina Ronacher, Lika Apriani, Mercedes Becerra, Alexander L. Chu, Jacob Creswell, Gustavo Diaz, Beatriz E. Ferro, Jerome T. Galea, Louis Grandjean, Harleen M. Grewal, Amita Gupta, Edward C. Jones-López, Léanie Kleynhans, Leonid Lecca, Peter Macpherson, Megan Murray, Diana Marín, Blanca I. Restrepo, Shri Vijay Shivakumar, Eileen Shu, Dhanasekaran Sivakumaran, Luan Nguyen Vo, Emily L. Webb, Andrew Copas, Ibrahim Abubakar, Molebogeng X. Rangaka

Social Work Faculty Publications

Objective: To investigate the prevalence of non-communicable diseases among household contacts of people with tuberculosis.

Methods: We conducted a systematic review and individual participant data meta-analysis. We searched Medline, Embase and the Global Index Medicus from inception to 16 May 2023. We included studies that assessed for at least one non-communicable disease among household contacts of people with clinical tuberculosis. We estimated the non-communicable disease prevalence through mixed effects logistic regression for studies providing individual participant data, and compared it with estimates from aggregated data meta-analyses. Furthermore, we compared age and sex-standardised non-communicable disease prevalence with national-level estimates standardised for …

Development And Optimization Of A Novel Eeev Microsphere Immunoassay: Using Xeno-Surveillance Methodology To Characterize Avian Herd Immunity, Kaitlyn Gabriele Maurais

Public Health Theses

Introduction: Eastern equine encephalitis virus (EEEV), a mosquito-borne alphavirus, is detected throughout the eastern United States. The primary enzootic vector, Culiseta melanura (Blacktailed mosquito), allows transmission among 50+ avian host species resulting in complex disease patterns. Spillover to dead-end host mammals, such as equines and humans, rarely occurs, however, human cases can cause severe neurological deficits and have a 30% mortality rate. Eco-epidemiology and avian host immunity patterns are not well characterized for EEEV and require ongoing surveillance to develop more targeted interventions. Methods: Xeno-surveillance is an approach to survey EEEV through hematophagous arthropods, instead of collecting samples from a …

Diagnostic Stewardship: Changing Behavior One Urine Culture At A Time, Beth Warne

Public Health Theses

Urinalysis and urine cultures are important diagnostic tools for diagnosing urinary tract infections. Often urine cultures are ordered without appropriate clinical indications of infection attributable to the urinary tract. Inappropriate urine culture ordering can have significant downstream effects and contribute to the unnecessary use of antibiotics, increased prevalence of Clostridioides difficile infections and antibiotic resistance, as well as wasted resources. A quality improvement project was undertaken at the Veterans Affairs Connecticut Healthcare System (VACHS) to decrease the ordering of inappropriate urine cultures. A new, optional electronic medical record urine culture ordering note requiring documented indication for the test was implemented …

Crowdsourcing Geospatial Data For Earth And Human Observations: A Review, Xiao Huang, Siqin Wang, Di Yang, Tao Hu, Meixu Chen, Mengxi Zhang, Guiming Zhang, Filip Biljecki, Tianjun Lu, Lei Zou, Connor Y. H. Wu, Yoo Min Park, Xiao Li, Yunzhe Liu, Hongchao Fan, Jessica Mitchell, Zhenlong Li, Alexander Hohl

Earth and Environmental Sciences Faculty Publications

The transformation from authoritative to user-generated data landscapes has garnered considerable attention, notably with the proliferation of crowdsourced geospatial data. Facilitated by advancements in digital technology and high-speed communication, this paradigm shift has democratized data collection, obliterating traditional barriers between data producers and users. While previous literature has compartmentalized this subject into distinct platforms and application domains, this review offers a holistic examination of crowdsourced geospatial data. Employing a narrative review approach due to the interdisciplinary nature of the topic, we investigate both human and Earth observations through crowdsourced initiatives. This review categorizes the diverse applications of these data and …

Saving Ourselves From Infection: A Theraputic Model Of Peer Led Education, Jessica Tkacs Way

West Chester University Master’s Theses

The purpose of this action research is to explore non-hierarchical peer led education as a means to end the Hepatitis C epidemic, promote empowerment and self-esteem in current injection drug users, and create a more global understanding of power structures that perpetuate opioid use so that those living with addiction are better able to educate, organize and fight for structural change. The current healthcare system is not able to test, treat or educate those most at risk for Hepatitis C infection or reinfection - people who inject drugs. The United States is currently in a losing battle with opioid addiction, …

Opportunities For Prep In High Risk Hiv Negative Patients, Steven Veselsky, Erin Smith, Amethyst Wilder, Misty Burkes, Nnamdi Ilouga, Jean B. Wiggins, Erik Shaw, William Hannah

South Atlantic Division GME Research Day 2024

No abstract provided.

Cerebrovascular Accident Complicating Pulmonary Tb: A Rare Co-Existence, Tesnim Hamdan, Iryna Witt, Nameer Ascandar, Srija Reddy

West Florida Division GME Research Day 2024

No abstract provided.

Hurricane Risk Perceptions And Evacuation Decision-Making In The Postvaccine Era Of Covid-19 In U.S. Coastal States Impacted By North Atlantic Hurricanes, Jennifer Collins, Elizabeth A. Dunn, Rashida K. Jones, Amy Polen, Nagashree R. Rao, Stephen Murphy, Mark Welford

School of Geosciences Faculty and Staff Publications

During peak disease transmission in 2021, the compounding threat posed by the pandemic and hurricane season required coastal states to understand evacuation behaviors during a major hurricane to inform the planning process. While research relating to hurricane evacuation behavior and perceptions of risk has increased since the start of the pandemic, there is minimal understanding of how perceptions have changed now the COVID-19 vaccine is available. A total of 1075 individuals across seven U.S. coastal states participated in a study on evacuation intentions postvaccine availability. Findings revealed that most survey participants (50.9%) preferred to stay home if a major hurricane …

Christianity And The Liberal(Ish) Income Tax, Andrew T. Hayashi

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Feasibility Assessment Of A Novel Isolation Care Tent In Uganda During The 2022, M. Jana Broadhurst, Rodgers R. Ayebare, David Brett-Major, Sean M. Carroll, Jacob Lacore, Alexander D. Laskey, James V. Lawler, Patricia Lord, Ruben M. Vazquez, Peter Waitt, Mohammed Lamorde

Journal Articles: Epidemiology

This case study describes a feasibility assessment of a novel isolation care tent used in health facilities in Uganda during the 2022 Sudan ebolavirus outbreak. The Isolation System for Treatment and Agile Response to High-Risk Infections Model 1B (ISTARI 1B) is a single-occupancy, portable, negative-pressure isolation tent designed for the safe delivery of standard care to patients with a communicable disease, including Ebola disease (Sudan). At the request of the Uganda Ministry of Health, the Makerere University Infectious Diseases Institute and University of Nebraska Medical Center partnered to evaluate 7 health facilities across 4 districts in Uganda for infrastructure, case …

Redesigning Surveillance Through The Global Emerging Infections Surveillance Program, David Brett-Major

Journal Articles: Epidemiology

No abstract provided.

Pandemic Impacts On The Workplace: Voices From Nh Small Businesses, Liu Yang, Ellen Smith Ahern, Karla Armenti

Institute on Disability

No abstract provided.

Landscape-Scale Epidemiological Dynamics Of Sars-Cov-2 In White-Tailed Deer, Joshua Hewitt, Grete Wilson-Henjum, Derek T. Collins, Timothy J. Linder, Julianna B. Lenoch, Jonathan D. Heale, Christopher A. Quintanal, Robert Pleszewski, Dillon S. Mcbride, Andrew S. Bowman, Jeffrey C. Chandler, Susan A. Shriner, Sarah N. Bevins, Dennis J. Kohler, Richard B. Chipman, Allen L. Gosser, David L. Bergman, Thomas J. Deliberto, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Understanding pathogen emergence in new host species is fundamental for developing prevention and response plans for human and animal health. We leveraged a large-scale surveillance dataset coordinated by United States Department of Agriculture, Animal and Plant Health Inspection Service and State Natural Resources Agencies to quantify the outbreak dynamics of SARS-CoV-2 in North American white-tailed deer (Odocoileus virginianus; WTD) throughout its range in the United States. Local epidemics in WTD were well approximated by a single-outbreak peak followed by fade out. Outbreaks peaked early in the northeast and mid- Atlantic. Local effective reproduction ratios of SARS-CoV-2 were between …

What Is Known, Unknown, And Needed To Be Known About Damage Caused By Wild Pigs, Kurt C. Vercauteren, Kim M. Pepin, Seth M. Cook, Sophie Mckee, Abigail Pagels, Keely J. Kohen, Ingrid A. Messner, Michael P. Glow, Nathan P. Snow

United States Department of Agriculture Wildlife Services: Staff Publications

Damage assessments provide evidence for initiating and evaluating management programs that protect natural resources and human livelihoods against invasive species. Wild pigs (Sus scrofa) cause extensive damage in their native and non-native ranges, but the extent of current damage and efficacy of management of the damage (i.e., population control of wild pigs, exclusion fencing, etc.) remains poorly described. We conducted a systematic review of physical damage caused by wild pigs to summarize what is known and identify knowledge gaps for damage assessment. Wild pig damage assessments have been overwhelmingly qualitative (84% of studies) and measured differently across studies, …

Tracking Sero-Molecular Trends Of Swine Brucellosis In Hawai'i And The Central Pacific, Thi Hai Au La, Ian A. Mcmillan, Prashant Dahal, Andrew H. Burger, Mahdi Belcaid, Darrin M. Phelps, Samuel M. Goldstein, Vienna R. Brown, Michael H. Norris

United States Department of Agriculture Wildlife Services: Staff Publications

Introduction

Brucellosis is a zoonotic disease of mammals caused by bacterial species of the Brucella genus. The reservoir for disease is typically mammals, with species of Brucella found infecting amphibians, bats, and marine mammals. Brucella spp. can pass directly to humans through contact with infected animals or their products. Brucella spp. can cause chronic debilitating infections in mammals, including humans, and is associated with spontaneous abortions in infected animals, causing reduced fecundity. In Hawai‘i, terrestrial species that could harbor Brucella spp. include swine, cattle, horses, and axis deer among others. The numerous feral swine in Hawai‘i are known to carry …