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2024

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The U.S. Southern Mothers Perspective On Affection, Destiny M. Rose Jan 2024

The U.S. Southern Mothers Perspective On Affection, Destiny M. Rose

College of Graduate Studies: Theses & Dissertations

This qualitative research study utilizes Murray Bowen’s Family Systems Theory and Kimberlé Crenshaw’s Intersectionality Theory to examine how ten mothers residing in what is identified as the U.S. Deep South (Georgia, Alabama, and South Carolina) perceive affection shown to their children by adults outside of their nuclear family. Additionally, this study considers the influence social class plays in how parents in the Deep South navigate and negotiate social and cultural norms when it comes to affection displays shown to their children. Data was collected using thematic analysis to describe how parents in parts of the Deep South perceive affection shown …


Training Underrepresented Minority Students For Careers In Public Health Leadership – Public Health Leaders Fellowship Program, Jigsa Tola Jan 2024

Training Underrepresented Minority Students For Careers In Public Health Leadership – Public Health Leaders Fellowship Program, Jigsa Tola

College of Graduate Studies: Theses & Dissertations

Background: Shortage and lack of diversity in the United States public health workforce is well documented and remains a challenge to meaningfully improving the health of the population. Although the diversity of the public health workforce has implications for access, care quality, and career opportunities in low-income communities, there is no strong mechanism by which minorities are trained to replenish the workforce. Morehouse College’s Public Health Leaders Fellowship Program (MC-PHLFP) is a cooperative program with the Centers for Disease Control and Prevention (CDC) to train undergraduate students for careers in public health leadership.

Purpose: The purpose of this research is …


The Effect Of First-Person Testimonial Versus Didactic Video Interventions On Attitudes And Behavioral Intentions Toward Buprenorphine, Tristan S. Fletcher Jan 2024

The Effect Of First-Person Testimonial Versus Didactic Video Interventions On Attitudes And Behavioral Intentions Toward Buprenorphine, Tristan S. Fletcher

College of Graduate Studies: Theses & Dissertations

Emerging adults exhibit disproportionately elevated levels of substance use disorders (Substance Abuse and Mental Health Services Administration [SAMHSA], 2021), opioid misuse (SAMHSA, 2021), and opioid use (Hu et al., 2017; Jones et al., 2015) compared to other age cohorts. If left untreated, opioid misuse and opioid use disorder can lead to various negative consequences, including premature death (Strang et al., 2020). Prior research indicates emerging adults have higher opioid-related mortality rates compared to other age groups in the United States (Gomes et al., 2018). Buprenorphine, an opioid partial agonist medication, is an effective intervention for opioid use disorder (Mattick et …


Social And Structural Determinants Of Health As Predictors Of Covid-19 Vaccine Hesitancy Among Older Adults In The United States, Kingsley Kalu Jan 2024

Social And Structural Determinants Of Health As Predictors Of Covid-19 Vaccine Hesitancy Among Older Adults In The United States, Kingsley Kalu

College of Graduate Studies: Theses & Dissertations

Background: Although vaccination is one of the greatest accomplishments in public health, some people, especially older adults, are reluctant to take vaccines. This study examined the association between the social and structural determinants of health and COVID-19 vaccine hesitancy among older adults in the United States.

Methods: Secondary data from the Health and Retirement Study (HRS) was used. The HRS participants were 65 years and older, and the sample size was 2311. Multinomial multivariable logistic regression models were conducted for this study.

Results: The study shows that social determinants of health (marital status, educational level) and structural determinants of health …


Cybercrime Victimization: Online Routine Behaviors, Guardianship, And Identity Theft Victimization In A Nationally Reflective Sample, Ifeoluwa Stella Elegbe Jan 2024

Cybercrime Victimization: Online Routine Behaviors, Guardianship, And Identity Theft Victimization In A Nationally Reflective Sample, Ifeoluwa Stella Elegbe

College of Graduate Studies: Theses & Dissertations

In this digital era, cybercrime victimization has emerged as a significant issue, with identity theft being one of the most prevalent forms. This study examines the relationship between online routine behaviors, guardianship, demographics, and identity theft victimization in a nationally representative sample of U.S. adults utilizing routine activities theory (RAT) as a conceptual

framework. The research applies statistical methods such as descriptive statistics, correlation analysis, and logistic regression models to examine theoretically oriented hypotheses. The

hypotheses suggest connections between different online habitual behaviors, steps taken to

protect oneself, demographic characteristics, and the extent to which one has been a victim …


What Does It Mean To Be The Goat: A Narrative Study On Retired White Male Elite Individual Sport Athletes?, Tyler Behrmann Jan 2024

What Does It Mean To Be The Goat: A Narrative Study On Retired White Male Elite Individual Sport Athletes?, Tyler Behrmann

College of Graduate Studies: Theses & Dissertations

The greatest of all time (GOAT) is a topic commonly discussed in sports today (Lundberg & Rosenberg, 2020). Despite this increased use of the term, there is a lack of research on the topic of the GOAT which could serve to benefit individuals in performance domains. The purpose of this qualitative exploratory study was to investigate characteristics that describe a GOAT and the impact these characteristics of the GOAT have on individuals. Two participants were included in this study. The participants were white male, retired, and individual sport athletes who competed in multiple World Championships. Participants were interviewed using semi-structured …


Letters To Myself ~ Reflections Of A New Teacher ~ A Curriculum Of Self, Sarah Brittany S. Greneker Jan 2024

Letters To Myself ~ Reflections Of A New Teacher ~ A Curriculum Of Self, Sarah Brittany S. Greneker

College of Graduate Studies: Theses & Dissertations

This is a nontraditional, very creative approach to dissertation writing. Using reflective poetic inquiry, I reflect on my experiences transitioning from pre-service to in-service teacher in the early childhood classroom. I taught for 7 years and encountered many situations that would have been beneficial to know prior to becoming a certified teacher. I explore overarching themes of coworker relationships, undergraduate program preparation, the various responsibilities, classroom environment, teacher evaluation, teacher perspective, and teacher mental health and well-being and how they each impact a teacher’s experience in the classroom. This is accomplished through the epistolary genre and letters to myself as …


Characterization Of Carbon Nanotube/Polystyrene Composites Prepared Via Microwave-Induced Polymerization, Hubert Agamasu Jan 2024

Characterization Of Carbon Nanotube/Polystyrene Composites Prepared Via Microwave-Induced Polymerization, Hubert Agamasu

College of Graduate Studies: Theses & Dissertations

Carbon nanotubes (CNTs), with their excellent mechanical properties, are well suited to the production of composites with good strength-to-weight ratio. However, the use of nanotubes as reinforcement is hampered by the lack of interaction between their inert surfaces and matrices. This, coupled with the van der Waal’s interactions between individual nanotubes, leads to agglomeration of CNTs in media. Functionalization is an efficient means to disperse nanotubes as well as increase their reactivity. The irradiation of CNTs with microwaves generates instantaneous, localized heating, being used in this work to trigger the rapid, thermal, free radical polymerization of styrene. Under microwaves, olefin-functionalized …


Exploring Black Queer Doctoral Student Experiences With Utilizing Campus Services, Mitchell Everett Jan 2024

Exploring Black Queer Doctoral Student Experiences With Utilizing Campus Services, Mitchell Everett

College of Graduate Studies: Theses & Dissertations

This study utilized narrative inquiry to examine the experiences of Black Queer Doctoral Students (BQDS) with campus services and their ability to ameliorate minority stress and establish community with other students minoritized by their sexual or gender identity. I used the minority stress model and intersectionality as frameworks to understand how students minoritized by their race and sexual identities experienced campus services. The minority stress model provided an explanation of the stress BQDS may experience due their minority identity (Meyer, 2003, 2013). Connecting to community is also an ameliorating factor in reducing minority stress. In addition, structural intersectionality addressed the …


Joy In The Focus, Focus On The Joy, Alicia Cully Jan 2024

Joy In The Focus, Focus On The Joy, Alicia Cully

College of Graduate Studies: Theses & Dissertations

This body of work, Joy in the Focus, Focus on the Joy is an engendered unspoken symbolic language generated from the handwritten words of the English language that are defined or viewed with positive connotations. These symbols are meant to spread the feelings each word embodies with what resonates with the priori or memory of the audience. The symbolic language is a key for an individual to make their own connections with how the symbol’s meaning makes them feel,, resulting in an openly welcome invitation to reach a focused joy in connecting with the displayed feeling(s). My drive to create …


Effects Of An 8-Week Undulating Training Program On Firefighter Body Composition, Muscular Fitness, And Occupational Performance, Dylan R. Brown Jan 2024

Effects Of An 8-Week Undulating Training Program On Firefighter Body Composition, Muscular Fitness, And Occupational Performance, Dylan R. Brown

College of Graduate Studies: Theses & Dissertations

BACKGROUND: Firefighting is a high-risk occupation that requires a certain level of health and fitness to ensure optimal occupational performance. Improving body composition by reducing fat mass and increasing muscular strength and power are two great methods for improving performance. Therefore, the purpose of this study is to examine how an 8-week undulating training program affects firefighter body composition, muscular strength/power, and occupational performance. METHODS: A total of 33 active male firefighters were recruited for this study. Prior to the start of the 8-week undulating program, all participants were pre-tested on several fitness variables including body composition, strength, …


Numerical Analysis Of A Novel Elastohydrodynamic Seal For Supercritical Co2 Power Cycles With Experimental Verification, Ali Akbor Topu Jan 2024

Numerical Analysis Of A Novel Elastohydrodynamic Seal For Supercritical Co2 Power Cycles With Experimental Verification, Ali Akbor Topu

College of Graduate Studies: Theses & Dissertations

Supercritical carbon dioxide (sCO2) power cycles outperform conventional thermodynamic cycles regarding the efficiency and equipment footprint because of its unique property of maintaining the density of liquid in the gaseous phase at supercritical state (304.13 K and 7.37 MPa). It has robust use in concentrated solar power, fossil fuel power plants, geothermal electricity, nuclear power, and ship propulsion. To fully utilize sCO2 power cycles, technology readiness must be demonstrated at 10-60 MWe scale, with a working temperature and pressure of 350-700°C, and 10-35 MPa respectively. A crucial obstacle to the full realization of this technology is the absence …


Dungeons And Dragons™ (D&D) As A Brief Intervention For College Students, Alexander W. Peralta Jan 2024

Dungeons And Dragons™ (D&D) As A Brief Intervention For College Students, Alexander W. Peralta

College of Graduate Studies: Theses & Dissertations

This quasi-experimental study investigated the effect of a table-top roleplaying game (ttrpg), specifically Dungeons and Dragons™ (D&D), on increasing feelings of social connection, decreasing perceived stress, increasing self-esteem and improving adjustment to college among first semester, first year students. participants signed up to either the D&D group or the comparison group. D&D participants (n = 18) attended five one-hour weekly D&D sessions, meanwhile the comparison group (n = 10) went through their first semester of college with no intervention, but completed the study measures at the same points in time as the D&D participants. All participants completed measures of social …


The Impact Of Financial Wellness On Student Success, Holly Hamilton Jan 2024

The Impact Of Financial Wellness On Student Success, Holly Hamilton

College of Graduate Studies: Theses & Dissertations

For many traditional-aged students, college can be their first major financial undertaking. Along with navigating the task of funding a college education, traditionally aged students may face additional financial challenges while entering adulthood. This financial responsibility can cause added stress for students and have a bearing on their financial wellness. This study explored the impact of financial wellness on students' abilities to succeed in college. Through the exploration of four financial wellness measures, financial self-efficacy, financial socialization, financial strain, and financial optimism, the researcher sought to first understand the relationships among the various wellness measures and then to determine what …


Exploring Artificial Intelligence And The Future Of Primary Care., Meghan Gilfoyle, K Taylor Bosworth, T M Ayodele Adesanya, Ashley Chisholm, Minika Ohioma, Bryce Ringwald, Chloe L Warpinski, Jacqueline K Kueper, Winston Liaw Jan 2024

Exploring Artificial Intelligence And The Future Of Primary Care., Meghan Gilfoyle, K Taylor Bosworth, T M Ayodele Adesanya, Ashley Chisholm, Minika Ohioma, Bryce Ringwald, Chloe L Warpinski, Jacqueline K Kueper, Winston Liaw

Ambulatory and Primary Care Articles

No abstract provided.


An Assessment Of Functional Characteristics In Macroinvertebrates And Fishes In The Lower Ogeechee River, Molly A. Mckeon Jan 2024

An Assessment Of Functional Characteristics In Macroinvertebrates And Fishes In The Lower Ogeechee River, Molly A. Mckeon

College of Graduate Studies: Theses & Dissertations

The southeastern United States is a hotspot for aquatic biodiversity; yet this region is also considered vulnerable to climate and land–use changes. The Ogeechee River is an unimpeded blackwater river in Georgia that drains into the Atlantic Ocean and a unique ecosystem due to the preservation of its natural state; Historically, research conducted in the river establishes a baseline for long-term ecological studies. The aim of this study is to compare aquatic macroinvertebrate and fish community composition data collected in 2014 to 2017 to a recently collected dataset from 2023 and document temporal changes. Water quality monitoring was performed throughout …


Cultivation Of A Commercially Important Macroalga (Ulva Sp) For Polyculture Research In Coastal Georgia, Kyle Mundy Jan 2024

Cultivation Of A Commercially Important Macroalga (Ulva Sp) For Polyculture Research In Coastal Georgia, Kyle Mundy

College of Graduate Studies: Theses & Dissertations

The Georgia coast has shown great potential for large-scale oyster aquaculture, and the rate at which the sector has grown demands implementation of novel techniques to ensure sustainability and success in the face of climate change. One practice – integrated multi-trophic aquaculture (IMTA) or polyculture – is known to have positive effects on the health and quality of farmed organisms and the surrounding environment through low pH/alkalinity amelioration, while also being a unique and viable way for a farming operation to diversify its products. To date, there has been no such attempt at investigating or demonstrating macroalgae culture in Georgia. …


Geoelectrical And Hydrochemical Characterization Of Submarine Groundwater Discharge In Florida Bay, Ifeanyi Emmanuel Eze Jan 2024

Geoelectrical And Hydrochemical Characterization Of Submarine Groundwater Discharge In Florida Bay, Ifeanyi Emmanuel Eze

College of Graduate Studies: Theses & Dissertations

Florida Bay, situated at the southern tip of Everglades National Park and underlain by the Miami Limestone formation, is an ecosystem of global significance. Over the past century, the bay has faced threats such as droughts, seagrass mortality, and hypersalinity. Despite various studies and management efforts, the dynamics of submarine groundwater discharge (SGD) in the region remain underexplored. Given that SGD plays a significant role in the chemical dynamics of coastal ecosystems, it warrants thorough investigation. This study aims to characterize the spatial and temporal patterns of SGD in Florida Bay by surveying three basins – Rankin, Whipray, and Rabbit …


Evaluation Of The Navy Shipshape Program At A Large Navy Military Treatment Facility: A Comprehensive Swot Analysis Approach, Nia Nur Maye Jan 2024

Evaluation Of The Navy Shipshape Program At A Large Navy Military Treatment Facility: A Comprehensive Swot Analysis Approach, Nia Nur Maye

College of Graduate Studies: Theses & Dissertations

The increasing problem of obesity among Navy service members (SMs) is a public health concern that impacts operational readiness and health risks. To combat obesity, the Navy has an official weight management initiative called ShipShape. This project aimed to conduct a Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis of ShipShape at a large Military Treatment Facility (MTF) in Portsmouth, Virginia. This program evaluation aimed to identify the internal and external factors that influenced the program's effectiveness to propose suggestions for improvement. Using quantitative and qualitative methods, the evaluation focused on conducting a paired t-test to analyze changes in Body Mass …


So Much Courage: Hemingway, War, And Rape, Tracie Nicolai Jan 2024

So Much Courage: Hemingway, War, And Rape, Tracie Nicolai

College of Graduate Studies: Theses & Dissertations

Weaving together Ernest Hemingway’s biography and literature with her own life, Tracie Nicolai analyzes the impact of Hemingway’s life and literature in the classroom and outside of it. War trauma is analyzed in relation to rape and its lasting effects, paralleling the impacts and the traumas that shape our philosophies and our lives. Nicolai explores how Hemingway wrote of war and his own injuries, and she discusses the distance evident between his own life experiences and his subsequent fiction writings. In separate vignettes in each chapter, Nicolai writes of her experience as a rape survivor and the lasting impact on …


Detecting Bearing Race Defects With Inductive Magnetic Reluctance Sensors And Artificial Neural Networks, Collin Daly Jan 2024

Detecting Bearing Race Defects With Inductive Magnetic Reluctance Sensors And Artificial Neural Networks, Collin Daly

College of Graduate Studies: Theses & Dissertations

This work proposes a method of detecting physical damage to bearing races in a rotational assembly by means of magnetic reluctance sensors generating a signal from a rotating gear-tooth wheel. A nominally sinusoidal signal is generated based on the rotation of a gearwheel with regularly spaced voids and lands. Detection is based on the time variance of the signal periodically in relation to the gearwheel and the bearing damage. The purpose of this work is to propose a process to detect and classify bearing race defects using existing sensors and neural networks for hazardous area equipment applications.


Development Of A Measure Assessing Adolescent Aggression: The Aggressive Behavior Risk Assessment- Adolescent- Parent Report (Abra-A-Pr), Katherine Fallon Jan 2024

Development Of A Measure Assessing Adolescent Aggression: The Aggressive Behavior Risk Assessment- Adolescent- Parent Report (Abra-A-Pr), Katherine Fallon

College of Graduate Studies: Theses & Dissertations

Although parent-report scales for general behavioral difficulties and aggression (e.g., verbal and physical aggression) exist, there are currently no measures assessing sexual behaviors in this context. Commonly, parent-report measures provide a few items relevant to behavioral aggression, and items encompassing sexually aggressive behaviors are frequently vague and non-specific in the actions being committed by the adolescent. The primary purpose of this project was to develop a comprehensive and multifaceted parent-report measure for aggressive behavior in adolescents. Three separate studies were conducted to evaluate the psychometric properties of the measure. Exploratory (EFA) and confirmatory factor analysis (CFA) were used to investigate …


Examining The Moderating Effect Of Self-Compassion Between Rumination And Alcohol Use, Victoria Forgea Allen Jan 2024

Examining The Moderating Effect Of Self-Compassion Between Rumination And Alcohol Use, Victoria Forgea Allen

College of Graduate Studies: Theses & Dissertations

Abundant research suggests alcohol use among college students as a public health concern (SAMHSA, 2014). Previous studies support rumination, a manner of responding to emotional distress which involves repetitively and passively focusing on the distress, is linked to problematic alcohol use among college students (Oswalt et al., 2020). On the other hand, not all college students who experience rumination engage in problematic alcohol use which suggests the presence of a moderating variable. Due to its emotion regulating abilities and positive associations to well-being, self-compassion may be on factor that affects the relationship between rumination and alcohol use (Diedrich et al., …


Development Of A Novel Measure To Assess For Alcohol Misuse In Older Adults: The Alcohol Misuse Scale For Older Adults (Amsoa), Nathan Jensen Jan 2024

Development Of A Novel Measure To Assess For Alcohol Misuse In Older Adults: The Alcohol Misuse Scale For Older Adults (Amsoa), Nathan Jensen

College of Graduate Studies: Theses & Dissertations

Alcohol is the most regularly used intoxicating substance in most geographic locations. Alcohol use in the United States specifically is well over global averages. While alcohol misuse is generally considered to be understood as a problem for younger adults, it is often unrecognized and understudied older adult populations. Currently, there is an absence of a comprehensive tool measuring for developmentally salient behaviors, symptoms, and features of alcohol misuse in older adulthood, which blocks researchers’ ability to measure alcohol misuse well. The purpose of this study is to develop a psychometrically valid and reliable assessment of alcohol misuse for older adult …


Social Support In Black Individuals: The Moderating Effects On The Relationship Between Resilience And Well-Being, Imani Elise Crosby Jan 2024

Social Support In Black Individuals: The Moderating Effects On The Relationship Between Resilience And Well-Being, Imani Elise Crosby

College of Graduate Studies: Theses & Dissertations

Black individuals possess numerous strengths and positive contributions that build strong communities and cultivate psychological well-being (Biglan et al., 2012). However, much of the current literature focuses on hardships Black individuals face, skewing the larger discourse of their lived experience. This exclusive focus on adversity often neglects pathways by which Black people thrive and flourish. It is important to consider how Black experiences relate to a sense of well-being. Resilience, or the ability to “bounce back” from adverse experiences is linked well-being outcomes (APA, 2012). However, it is unknown whether the promotive effects of resilience directly contribute to well-being outcomes …


Functional Monitoring For Run-Time Assurance Of A Real-Time Cyber Physical System, Matthew W. Gelber Jan 2024

Functional Monitoring For Run-Time Assurance Of A Real-Time Cyber Physical System, Matthew W. Gelber

Theses and Dissertations

As cyber-physical systems (CPS) become more integrated into everyday life, the security of these systems must also be considered during their development due to their ever-increasing importance. With the growth of physical components in the system, more autonomous control requirements, and increased dependence on proper functionality, verifying system safety and correct operation becomes increasingly difficult. CPS have become more complex through the combination of additional hardware and the resulting interconnected software in many layers, each requiring unique security solutions. One example of such a safety-critical CPS embedded system is the Flight Control System (FCS) of an Unmanned Aerial System (UAS). …


The Patient Experience Of Language Discordance And Interpreter Services In The Emergency Department, Keri L. Baker Jan 2024

The Patient Experience Of Language Discordance And Interpreter Services In The Emergency Department, Keri L. Baker

Theses and Dissertations

Background: Clear communication is critical to the interaction of a patient and medical provider. For non-English speaking patients, language discordance, described as the lack of proficiency in a shared language, with the medical team results in a poor patient experience and poor patient outcomes. The predominant solution to language discordance is the use of interpreter services, however these services are underused in the emergency department (ED). Studies examining underuse of interpreter services have primarily focused on the clinician and little is known about the patient’s influence on the use of interpreter services.

Methods: Semi-structured interviews were conducted with 12 Spanish-speaking …


Covid-19 Vaccine And Infection And The Relationship To Lichen Planus Flare-Ups: A Self-Reported Survey Study, Sara Kube Jan 2024

Covid-19 Vaccine And Infection And The Relationship To Lichen Planus Flare-Ups: A Self-Reported Survey Study, Sara Kube

Theses and Dissertations

Purpose: The aim of this study was to determine if there is an increased occurrence of oral lichen planus flare-ups after COVID-19 vaccination or infection.

Methods: An 11-item questionnaire was dispersed to patients with a diagnosis of oral lichen planus. The survey contained questions regarding the patient’s history of COVID-19 vaccination and infection as it relates subjective oral lichen planus flare-ups (i.e. oral redness, oral ulcerations, and/or oral pain/discomfort).

Results: Self-reported flares were significantly associated with whether or not vaccine side effects were also reported (p-value=0.0053). For those who reported experiencing side effects (tiredness, headache, muscle pain, chills, fever, nausea), …


Utilizing Hemoglobin Binding Kinetics And X-Ray Crystallography In Sickle Cell Disease Drug Development, Ahmed Alghamdi Jan 2024

Utilizing Hemoglobin Binding Kinetics And X-Ray Crystallography In Sickle Cell Disease Drug Development, Ahmed Alghamdi

Theses and Dissertations

ABSTRACT

UTILIZING HEMOGLOBIN BINDING KINETICS AND X-RAY CRYSTALLOGRAPHY IN SICKLE CELL DISEASE DRUG DEVELOPMENT

By Ahmed Alghamdi, M.Sc. in Medicinal Chemistry

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Medicinal Chemistry at Virginia Commonwealth University.

Virginia Commonwealth University, 2024.

Director: Dr. Martin K. Safo Professor, Department of Medicinal Chemistry

Introduction: Sickle Cell Disease (SCD) is characterized by severe hemolytic anemia, recurrent painful crises, and chronic organ damage, posing significant challenges to patients' quality of life and longevity. While current FDA-approved therapies offer symptomatic relief, they do not address the underlying molecular …


Mechanistic Analysis Of Four-Way Dna Junctions And Cytokine-Binding Aptamers For Therapeutic Interventions, Roaa S. Mahmoud Jan 2024

Mechanistic Analysis Of Four-Way Dna Junctions And Cytokine-Binding Aptamers For Therapeutic Interventions, Roaa S. Mahmoud

Theses and Dissertations

DNA is inherently dynamic and topologically diverse and can fold into many different structures. Besides the canonical Watson-Crick structure, other higher-order structures such as G-quadruplexes (G4), i-motifs (iM), and four-way DNA junctions are possible. Although these high-order DNA structures are known to form transiently, they are important due to the crucial roles they play in many cellular processes including DNA replication, recombination, and repair. Among these DNA structures, 4-way junctions (also known as Holliday junctions, HJ) which are formed during the repair of double-strand DNA breaks (DSBs) and interact with proteins have garnered significant attention due to their central role …