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2024

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Spatial Gap-Filling Of Himawari-8 Hourly Aod Products Using Machine Learning With Model-Based Aod And Meteorological Data: A Focus On The Korean Peninsula, Youjeong Youn, Seoyeon Kim, Seung Hee Kim, Yangwon Lee Nov 2024

Spatial Gap-Filling Of Himawari-8 Hourly Aod Products Using Machine Learning With Model-Based Aod And Meteorological Data: A Focus On The Korean Peninsula, Youjeong Youn, Seoyeon Kim, Seung Hee Kim, Yangwon Lee

Institute for ECHO Articles and Research

Given the complex spatiotemporal variability of aerosols, high-frequency satellite observations are essential for accurately mapping their distribution. However, optical remote sensing encounters difficulties in detecting Aerosol Optical Depth (AOD) over cloud-covered regions, creating data gaps that limit comprehensive environmental analysis. This study introduces a spatial gap-filling method for Himawari-8/Advanced Himawari Imager (AHI) hourly AOD data, using a Random Forest (RF) model that integrates meteorological variables and model-based AOD data. Developed and validated over South Korea from 1 January to 31 December 2019, the model effectively improved data coverage from 6% to 100%. The approach demonstrated high performance in blind tests, …


Broad-Spectrum Resistance To Fungal Foliar Diseases In Wheat: Recent Efforts And Achievements, Amira M.I. Mourad, Asmaa A.M. Ahmed, P. Stephen Baenziger, Andreas Börner, Ahmed Sallam Nov 2024

Broad-Spectrum Resistance To Fungal Foliar Diseases In Wheat: Recent Efforts And Achievements, Amira M.I. Mourad, Asmaa A.M. Ahmed, P. Stephen Baenziger, Andreas Börner, Ahmed Sallam

Department of Agronomy and Horticulture: Faculty Publications

Wheat (Triticum spp.) is one of the most important cereal crops in the world. Several diseases affect wheat production and can cause 20-80% yield loss annually. Out of these diseases, stripe rust, also known as yellow rust (Puccinia striiformis f. sp. tritici), stem rust (Puccinia graminis f. sp. tritici), leaf rust (Puccinia recondita), and powdery mildew (Blumeria graminis f. sp. tritici) are the most important fungal diseases that infect the foliar part of the plant. Many efforts were made to improve wheat resistance to these diseases. Due to the continuous advancement in …


Across Borders: Understanding Transnational Fathering Of Overseas Filipino Worker (Ofw) Fathers, Kristine L. Andaya, Marilag M. Baricaua, Charlote I. Marquez Nov 2024

Across Borders: Understanding Transnational Fathering Of Overseas Filipino Worker (Ofw) Fathers, Kristine L. Andaya, Marilag M. Baricaua, Charlote I. Marquez

Social Sciences and Development Review

This research sought to understand the lived experiences of OFW fathers in transnational fathering and explore their motivations and the decision making process that resulted in their intention and willingness to work abroad despite having to leave their children behind. This study also aimed to describe their ideal construct of a father and how they negotiate this construct with their actual experiences as an OFW father. Nine (9) OFW fathers were interviewed regarding their experiences as OFWs who practice fathering from a distance. In agreement with the premises of Lee’s theory of migration, the OFW father’s decision to work overseas …


Reaching The Marginalized: Do Education Expenditure And Other Indicators Alleviate Poverty In The Philippines, Sofia Mae O. Nuñez, Reign Christine M. Aguado, Jaira Mei B. Barua, Charisse Mae O. Capariño Nov 2024

Reaching The Marginalized: Do Education Expenditure And Other Indicators Alleviate Poverty In The Philippines, Sofia Mae O. Nuñez, Reign Christine M. Aguado, Jaira Mei B. Barua, Charisse Mae O. Capariño

Social Sciences and Development Review

This study examines if government expenditure and other indicators alleviate poverty in the Philippines. This study employs time series data of unemployment rate, business confidence, and education expenditures from 2001-2022, making it to 21 observations. In this paper, several tests are used, namely Augmented Dickey-Fuller (ADF) for stationarity, Breusch Godfrey Serial Correlation LM Test, Variance Inflation Factor (VIF) for autocorrelation and multicollinearity. The Johansen Cointegration and the Pairwise Granger Causality Test were also performed to find out if there is a long-run relationship and causality between the variables. The results reveal that there is a long-run relationship and bidirectional causality …


A Comprehensive Analysis Of The Implementation Of Government Procurement Law In Metro Manila: Basis For Good Governance Among Local Government Units, Omar R. Manlapas, Christopher C. Mantillas Nov 2024

A Comprehensive Analysis Of The Implementation Of Government Procurement Law In Metro Manila: Basis For Good Governance Among Local Government Units, Omar R. Manlapas, Christopher C. Mantillas

Social Sciences and Development Review

Public procurement is a standard procedure for the government to buy products and services and develop infrastructure projects. Rigid procurement benefits northern hemisphere nations like the European Union (EU). In Australia, they use “Commonwealth Procurement Rules” to get value for money by strengthening local capabilities and skills (Allen, 2020). In a comparative study, Asia outperformed Africa in all parameters except voice, accountability, and procurement complaint handling. (Amankwa & Tetteh, 2022). This research evaluated the three (3) Highly Urbanized Cities based on their scores on four (4) pillars: Economic Dynamism, Government Efficiency, Infrastructure, Resiliency, and Innovation. (Manila, Pasay, and Quezon City) …


When South Meets South: A Case Of African-Philippines Treaty Relations, Noel Y. Sinco Nov 2024

When South Meets South: A Case Of African-Philippines Treaty Relations, Noel Y. Sinco

Social Sciences and Development Review

The African-Philippines Relations connected through the manifestation of bilateral agreements with the respective African States with Egypt obtaining the most of it. The World Bank (2023) established the Small States Forum (SSF) mostly composed of the African States. The Philippines and specific African States share surprising similarities that qualify them as Small States under the World Bank (2023) definition. Sadly, the Philippines did not give enough attention to increase its African diplomatic base. The study mainly aims to analyze the depth of Philippine Relations with these African Small States and what diplomatic instruments these two states connect. The study found …


High School Students Join Uab Choirs In Song For "Christmas At The Alys" On Dec. 5, Staff Nov 2024

High School Students Join Uab Choirs In Song For "Christmas At The Alys" On Dec. 5, Staff

Browse All News

No abstract provided.


High School Students Join Uab Choirs In Song For "Christmas At The Alys" On Dec. 5, Shannon Thomason Nov 2024

High School Students Join Uab Choirs In Song For "Christmas At The Alys" On Dec. 5, Shannon Thomason

Browse All News

No abstract provided.


Using High-Frequency Oscillations From Brief Intraoperative Neural Recordings To Predict The Seizure Onset Zone, Behrang Fazli Besheli, Zhiyi Sha, Jay R Gavvala, Sacit Karamursel, Michael Quach, Chandra Prakash Swamy, Amir Hossein Ayyoubi, Alica M Goldman, Daniel J Curry, Sameer A Sheth, David Darrow, Kai J Miller, David J Francis, Gregory A Worrell, Thomas R Henry, Nuri F Ince Nov 2024

Using High-Frequency Oscillations From Brief Intraoperative Neural Recordings To Predict The Seizure Onset Zone, Behrang Fazli Besheli, Zhiyi Sha, Jay R Gavvala, Sacit Karamursel, Michael Quach, Chandra Prakash Swamy, Amir Hossein Ayyoubi, Alica M Goldman, Daniel J Curry, Sameer A Sheth, David Darrow, Kai J Miller, David J Francis, Gregory A Worrell, Thomas R Henry, Nuri F Ince

Faculty, Staff and Students Publications

BACKGROUND: While high-frequency oscillations (HFOs) and their stereotyped clusters (sHFOs) have emerged as potential neuro-biomarkers for the rapid localization of the seizure onset zone (SOZ) in epilepsy, their clinical application is hindered by the challenge of automated elimination of pseudo-HFOs originating from artifacts in heavily corrupted intraoperative neural recordings. This limitation has led to a reliance on semi-automated detectors, coupled with manual visual artifact rejection, impeding the translation of findings into clinical practice.

METHODS: In response, we have developed a computational framework that integrates sparse signal processing and ensemble learning to automatically detect genuine HFOs of intracranial EEG data. This …


Ezh2 Delays Activation Of Differentiation Genes During Normal Cerebellar Granule Neuron Development And In Medulloblastoma, James Purzner, Alexander S Brown, Teresa Purzner, Lauren Ellis, Sara Broski, Ulrike Litzenburger, Kaytlin Andrews, Aryaman Sharma, Xin Wang, Michael D Taylor, Yoon-Jae Cho, Margaret T Fuller, Matthew P Scott Nov 2024

Ezh2 Delays Activation Of Differentiation Genes During Normal Cerebellar Granule Neuron Development And In Medulloblastoma, James Purzner, Alexander S Brown, Teresa Purzner, Lauren Ellis, Sara Broski, Ulrike Litzenburger, Kaytlin Andrews, Aryaman Sharma, Xin Wang, Michael D Taylor, Yoon-Jae Cho, Margaret T Fuller, Matthew P Scott

Faculty, Staff and Students Publications

Medulloblastoma (MB) is the most common malignant brain tumour in children. The Sonic Hedgehog (SHH)-medulloblastoma subtype arises from the cerebellar granule neuron lineage. Terminally differentiated neurons are incapable of undergoing further cell division, so an effective treatment for this tumour could be to force neuronal differentiation. Differentiation therapy provides a potential alternative for patients with medulloblastoma who harbor mutations that impair cell death pathways (TP53), which is associated a with high mortality. To this end, our goal was to explore epigenetic regulation of cerebellar granule neuron differentiation in medulloblastoma cells. Key regulators were discovered using chromatin immunoprecipitation with high-throughput sequencing. …


Difficult To Treat Depression: Focus On Approach, Algorithms, And Access, Jordan F Karp, Roberta D Brinton, Jay C Fournier, Lisa Harding, Manish K Jha, Eric J Lenze, Sanjay J Mathew, Samantha Meltzer-Brody, David C Mohr, Patricio Riva-Posse, Ilse Wiechers, Nolan R Williams Nov 2024

Difficult To Treat Depression: Focus On Approach, Algorithms, And Access, Jordan F Karp, Roberta D Brinton, Jay C Fournier, Lisa Harding, Manish K Jha, Eric J Lenze, Sanjay J Mathew, Samantha Meltzer-Brody, David C Mohr, Patricio Riva-Posse, Ilse Wiechers, Nolan R Williams

Staff and Researcher Publications

The pandemic refocused interest on the burden of depression across the lifespan; the increased efforts to prevent and treat depression are now a priority of health care systems, insurers, patient advocates, digital therapeutic engineers, telemedicine platforms, and community health agencies. However, the challenges of treating depression to remission in adult patients who do not respond to first, second, or third levels of oral pharmacotherapy remain. The increased prevalence of these conditions is at odds with the shrinking psychiatric workforce. Since addressing difficult to treat depression is situated in a rapidly evolving treatment landscape, The University of Arizona College of Medicine-Tucson …


Study On The Seasonal Endobacterial Profile Of Avicennia Officinalis, Focusing On Core Bacterial Consortia Within Mangrove Pneumatophores, Devi R R, Vinod Prabhakar Nov 2024

Study On The Seasonal Endobacterial Profile Of Avicennia Officinalis, Focusing On Core Bacterial Consortia Within Mangrove Pneumatophores, Devi R R, Vinod Prabhakar

Karbala International Journal of Modern Science

Microhabitats are smaller pockets of ecosystems with unique conditions and they serve as major contributors of species richness. Mangrove plants offer a diverse array of such microhabitats (rhizosphere, phyllosphere, endosphereetc), and the inhabitant bacteria benefit the host by providing better salinity tolerance, faster and better nutrient mobilization, protection from phytopathogens and assistance in seed germination. Identification of such beneficial bacteria,their growth requirementsandmetabolism, willhave direct application in the field of agriculture and ecosystem restoration. Hence in this study, effort has been made to elucidate the seasonal numerical and compositional profile of pneumatophore bacterial consortia of Avicennia officinalis, from the mangrove …


Human-Machine Communication: Complete Volume. Volume 9 Nov 2024

Human-Machine Communication: Complete Volume. Volume 9

Human-Machine Communication

This is the complete volume of HMC Volume 9.


Towards Human-Machine Collaboration In Autonomous Material Handling On Construction Sites, Jyrki Oraskari, Lukas Kirner, Marit Zöcklein, Sigrid Brell-Cokcan Nov 2024

Towards Human-Machine Collaboration In Autonomous Material Handling On Construction Sites, Jyrki Oraskari, Lukas Kirner, Marit Zöcklein, Sigrid Brell-Cokcan

Human-Machine Communication

In the contemporary construction industry, the shortage of skilled labor has prompted the exploration of automation as a remedy and machine autonomy as a potential solution to the environmental conditions at the site. This research explores the balance between human oversight and the independent decision-making capabilities of robots for material delivery on construction sites. Using a scenario-based approach, autonomy in construction robotics is evaluated across four human-machine interaction cases with spatial and temporal dimensions. The expected outcomes revolve around improved safety through better human-machine communication and establishing an interoperable data model to enhance robot autonomy. This aims to automate tasks …


Accomplishing Robotic Autonomy: The Complexities Of Sociotechnical Care And Agency In The Laboratory, Yifan Xu, Elliott Hauser Nov 2024

Accomplishing Robotic Autonomy: The Complexities Of Sociotechnical Care And Agency In The Laboratory, Yifan Xu, Elliott Hauser

Human-Machine Communication

Effective ethical interventions in emerging technologies such as robotic autonomy demand situated understandings of the practices that shape them. Drawing upon a year of participatory ethnography, this study examines the sociomaterial practices used to accomplish robotic agency in an engineering research laboratory. Ironically, the robot was often a helpless, even pathetic, figure. Roboticists displayed an attitude of surprisingly genuine, diligent, and self-effacing care toward the robot as they helped enable it to perform basic competencies such as picking up a bottle. Using a practice theory, we show how roboticists’ care practices, motivated and sustained by anticipatory narratives of robotic agency, …


Wired To Offend: Cancel Culture Meets Generative Artificial Intelligence, Andrew Prahl, Shanice Koh Jie Qing, Justina Tan Ann Qi Nov 2024

Wired To Offend: Cancel Culture Meets Generative Artificial Intelligence, Andrew Prahl, Shanice Koh Jie Qing, Justina Tan Ann Qi

Human-Machine Communication

Cancel culture has been limited to individuals and corporations being cancelled. However, AI is also getting cancelled, challenging our understanding of machine autonomy and cancel culture. This paper investigates how AI cancellation is discussed on X (Twitter) using a recent AI cancellation incident involving Nothing, Forever, an AI-generated parody of Seinfeld. Qualitative content analysis is performed on 734 relevant posts to extract the main categories dominating the discourse, including emotional expression, attitudes toward AI, and discussion of human versus AI qualities. The results provide insights regarding how people perceive the autonomy of AI and who is responsible for AI output.


Autonomy And Agency In Farming: Exploring Human, Machine, And Animal Dynamics, Ricarda Drüeke, Corinna Peil Nov 2024

Autonomy And Agency In Farming: Exploring Human, Machine, And Animal Dynamics, Ricarda Drüeke, Corinna Peil

Human-Machine Communication

Human-Machine Communication is reshaping the agricultural sector as digital technologies and automated systems transform farms into complex communicative environments. Farms, which serve as both workplaces and living spaces, uniquely integrate these technologies, yet their impact on farmers’ daily practices, labor, and decision-making remains underexplored. Through an ethnographic approach involving qualitative interviews and farm visits in Austria and southern Germany, the study investigates the interactions among farmers, automated technologies, smart devices, and animals. Using Actor-Network Theory, the redistribution of labor and agency in smart farming is explored. This analysis examines two forms of human-machine relations: the dynamics of automation and autonomy …


Human-Machine Relations And Relational Autonomy, Hendrik Kempt, Camilla Colombo, Saskia K. Nagel Nov 2024

Human-Machine Relations And Relational Autonomy, Hendrik Kempt, Camilla Colombo, Saskia K. Nagel

Human-Machine Communication

The ever-growing use of interactive technologies and digitization processes in decisionmaking contexts raises key challenges to the conceptualization of autonomy. Starting from the shortcomings of individualistic models, we argue that relational accounts of autonomy provide a more adequate characterization of human beings as socially embedded and integrated. By introducing a decision-theoretic framework, and further theoretical elaboration, we suggest a substantial account of relational autonomy incorporating machines and technologies within the significant relations entertained by agents. Besides optimizing decision-making performances, human-machine interactions could genuinely support and enhance individual autonomy, by fostering human connections, expanding the individual’s social context with additional perspectives, …


From Automation To Autonomy: Human Machine Relations In The Age Of Artificial Intelligence, Caja Thimm, Gabriele Gramelsberger, Maximilian Mayer, Frank T. Piller Nov 2024

From Automation To Autonomy: Human Machine Relations In The Age Of Artificial Intelligence, Caja Thimm, Gabriele Gramelsberger, Maximilian Mayer, Frank T. Piller

Human-Machine Communication

The shift from automation to autonomy marks a new chapter in human-machine relations, especially in the context of the expanding and diversifying applications of Artificial Intelligence (AI). As machines gain capabilities that resemble autonomous agency, the boundary between human and machine autonomy blurs, challenging traditional concepts of agency, control, and independence. This special issue examines the multidisciplinary perspectives on autonomy in the digital age, addressing the complexities of attributing autonomy to machines and AI systems. Philosophical, sociological, and technical approaches converge to explore how emerging forms of machine autonomy impacts human agency, freedom, and decision-making, with applications spanning from autonomous …


Becoming-Religion: Re-/Thinking Religion With A.N. Whitehead And Keiji Nishitani, Kenneth C. Masong Nov 2024

Becoming-Religion: Re-/Thinking Religion With A.N. Whitehead And Keiji Nishitani, Kenneth C. Masong

Budhi: A Journal of Ideas and Culture

For Whitehead and Nishitani, a rethinking of religion necessitates a rethinking of the metaphysics that underlie one’s concept of religion. The dynamism of religion is unveiled only within the metaphysical grounding of an ontology that accommodates the philosophical preference of “becoming” as an ultimate category of reality. The novelty of Whitehead’s theory of religion lies in the process metaphysics that is presupposes. For him, religion, like the whole of reality, is inherently developing and evolving. What Nishitani offers is a rethinking of Western understanding of religion by way of an Asian speculative approach grounded in Zen Buddhism. He argues that …


Conquer And Prevail Issue 176 November 21 2024, Wofford College. Office Of Marketing And Communications Nov 2024

Conquer And Prevail Issue 176 November 21 2024, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.


What Works When Working Together?: Cross-Sector Collaboration Barriers & Facilitators Of A Built Environment Health Impact Assessment In Southern Nevada, Maxim Gakh, Courtney Coughenour, Bertille Assoumou, Emily C. Strickler, Timothy J. Bungum, Jennifer R. Pharr, Pashtana Usufzy, Megan Mcdonough, Nicole Williams Bungum, Mindy Meacham Nov 2024

What Works When Working Together?: Cross-Sector Collaboration Barriers & Facilitators Of A Built Environment Health Impact Assessment In Southern Nevada, Maxim Gakh, Courtney Coughenour, Bertille Assoumou, Emily C. Strickler, Timothy J. Bungum, Jennifer R. Pharr, Pashtana Usufzy, Megan Mcdonough, Nicole Williams Bungum, Mindy Meacham

Environmental & Global Health Faculty Research

Purpose: Cross-sector collaboration can improve community health because decisions made across sectors influence health. Health Impact Assessments (HIAs) and other health-focused, cross-sector collaborations encounter challenges. This case study uses a completed HIA to explore factors impeding and supporting health-related cross-sectoral collaboration.

Methods: Semi-structured key informant interviews with 10 of 12 HIA working group participants were conducted and analysed using a content analysis approach.

Results: Analysis generated 48 codes across seven themes in three primary groups: HIA as a collaborative tool; logistical and systemic barriers; and benefits and logistical, interpersonal, and sectoral facilitators. Recognizing the importance of knowledge, analysis, and …


Common Liver Conditions, Robert W Steele, Ryan T. Fischer Nov 2024

Common Liver Conditions, Robert W Steele, Ryan T. Fischer

Pediatrics in Practice: A CME Podcast

In this episode, Dr. Ryan Fischer shares his expertise on genetic liver diseases affecting children. Explore the latest advancements in diagnostic techniques and treatments, including genetic screening and their impact on transplant outcomes. Tune in to understand the relationship between genetics and pediatric liver conditions in 2024.

Click here to stream the podcast episode.


Common Cases Of Diabetes, Robert W Steele, Ryan J. Mcdonough Nov 2024

Common Cases Of Diabetes, Robert W Steele, Ryan J. Mcdonough

Pediatrics in Practice: A CME Podcast

Click here to stream the podcast episode.


Administration Patterns Of Magnesium Sulphate For Women With Preeclampsia And Immediate Newborn Outcomes In Kawempe National Referral Hospital-Uganda: A Cohort Study, Christopher J. Burant, Shirley Moore, Carol Blixen, Martha Sajatovic Nov 2024

Administration Patterns Of Magnesium Sulphate For Women With Preeclampsia And Immediate Newborn Outcomes In Kawempe National Referral Hospital-Uganda: A Cohort Study, Christopher J. Burant, Shirley Moore, Carol Blixen, Martha Sajatovic

Faculty Scholarship

Background: Preeclampsia is the second leading cause of maternal death in Uganda. WHO recommends using magnesium sulphate (MgSO4) to prevent and treat preeclampsia with severe features (PEC) and eclampsia. MgSO4 is used to prevent eclampsia and treat women who experience an eclamptic convulsion to avoid severe maternal/infant illnesses and death. We set out to assess MgSO4 administration patterns in women with PEC or eclampsia and the immediate newborn outcomes of neonates. Methods: This was an analytical observational cohort study at Kawempe National Referral Hospital in Uganda. Two hundred ten pregnant mothers with PEC or eclampsia were recruited in the study …


With Fear, Favor, And Flawed Analysis: Decision-Making In The U.S, Immigration Courts, Karen Musalo, Anna O. Law, Annie P. Daher, Katharine Donato, Chelsea Meinders Nov 2024

With Fear, Favor, And Flawed Analysis: Decision-Making In The U.S, Immigration Courts, Karen Musalo, Anna O. Law, Annie P. Daher, Katharine Donato, Chelsea Meinders

Publications and Research

Immigration judges (IJs), housed within the Executive Office for Immigration Review within the Department of Justice (DOJ), make decisions in asylum and withholding claims, which are life or death matters. And although their title is “judge,” IJs are DOJ attorneys who lack independence and are par- ticularly susceptible to political pressures. Federal court judges and scholars alike have criticized the quality and fairness of IJ decision-making, and many studies have been carried out to better understand the factors that impact it. The prior studies have relied principally on quantitative data because IJ decisions are not publicly available or searchable in …


November 24, 2024, Csusb Nov 2024

November 24, 2024, Csusb

Coyote Chronicle (1984-)

No abstract provided.


Statistical Analysis And Modeling Of Colon Cancer, Nessrin Bukhshim Nov 2024

Statistical Analysis And Modeling Of Colon Cancer, Nessrin Bukhshim

USF Tampa Graduate Theses and Dissertations

Cancer is considered a health issue in the world. Many cancer research studies focus on improving the survival time of patients diagnosed with cancer, and they make an effort to find the methods that help them detect cancer and find effective treatments to increase the patient's survival time. In this study, we aim to understand the behavior of malignant tumor size in four stages. Our investigation seeks to uncover whether any statistically significant difference exists between the malignant tumor sizes of male and female patients at different cancer stages. We also investigate whether any parametric probability distribution function best fits …


Γ -Aapeptides Targeting Amyloid-Β Pathway And Neural Repair For Alzheimer’S Disease Treatment, Ning Shen Nov 2024

Γ -Aapeptides Targeting Amyloid-Β Pathway And Neural Repair For Alzheimer’S Disease Treatment, Ning Shen

USF Tampa Graduate Theses and Dissertations

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques and progressive neuronal degeneration. Despite extensive research, no treatments have been able to effectively halt or reverse the progression of the disease. This study aimed to evaluate the therapeutic potential of two novel γ-AApeptides, HW-C9 and 125-6b, in AD treatment, assessing both their individual and combined effects. HW-C9 was designed to inhibit Aβ aggregation, while 125-6b was developed to promote neuronal growth and repair. Initially, the therapeutic effects of HW-C9 and 125-6b were assessed both in vitro and in vivo. The results showed that HW-C9 …


Acoustic Energy For Use In Mass Spectrometry, Ashton N. Taylor Nov 2024

Acoustic Energy For Use In Mass Spectrometry, Ashton N. Taylor

USF Tampa Graduate Theses and Dissertations

Analyzing lipid assemblies, including synthetically produced liposomes and naturally produced extracellular vesicles (EVs), is challenging due to their size, diverse composition, and tendency to aggregate. EVs contain a complex variety of lipids, proteins, and other metabolites. EVs composition can provide us insight into what is happening inside the body and a subcellular level and have potential for noninvasive biomarkers. Liposomes are vesicles that form with a simple phospholipid bilayer membrane and play important roles in drug delivery systems. The use of mass spectrometry (MS) allows for broad analysis of lipids from different classes but their release from the higher order …