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2024

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Home Births Among Ethnic Minority Communities In Bokeo Province, Lao People's Democratic Republic, Jukkrit Wungrath, Rungrasami Sriwongphan, Krissana Kapheak, Wanchalerm Ritthimon Nov 2024

Home Births Among Ethnic Minority Communities In Bokeo Province, Lao People's Democratic Republic, Jukkrit Wungrath, Rungrasami Sriwongphan, Krissana Kapheak, Wanchalerm Ritthimon

Kesmas

Home births among ethnic minorities in developing countries pose significant risks to maternal and neonatal health. In Lao PDR, the government has taken steps to manage home births through training traditional birth attendants, improving transportation, and establishing referral systems. However, high home birth rates in regions like Bokeo remain concerning. This review emphasized the need for more skilled birth attendants and better access to emergency obstetric care in rural, ethnic minority areas. This review used 40 articles published between 2000 and 2023 and highlighted gaps in research regarding healthcare access, cultural practices, socioeconomic barriers, and the role of traditional birth …


Economic Growth, Poverty Gap, And Health Inequality: Implications Based On Panel Analysis Of Organization For Economic Cooperation And Development Data, Sangik Han Nov 2024

Economic Growth, Poverty Gap, And Health Inequality: Implications Based On Panel Analysis Of Organization For Economic Cooperation And Development Data, Sangik Han

Kesmas

This study investigated the impact of economic growth and income distribution on health inequality using data from the Organization for Economic Cooperation and Development (OECD). Employing a panel analysis, this study amalgamated 21 years of data (spanning from 2000 to 2020) from 37 OECD countries. The dependent variables (life expectancy and avoidable mortality) were scrutinized against independent variables (gross domestic product and poverty gap). Control variables encompassed body mass index, consumption patterns, smoking rates, health workers availability, number of beds in health facilities, national medical expenses, and unemployment rates. This study revealed significant associations between economic growth, poverty gap, and …


Social Determinants Of Neonatal Health Outcomes In Indonesia: A Multilevel Regression Analysis, Rooswanti Soeharno, Amal Chalik Sjaaf Nov 2024

Social Determinants Of Neonatal Health Outcomes In Indonesia: A Multilevel Regression Analysis, Rooswanti Soeharno, Amal Chalik Sjaaf

Kesmas

Indonesia’s neonatal mortality rate remains alarmingly high. This study addressed the determinants of neonatal outcomes in Indonesia, including the effects of a decentralized health system, socioeconomic disparities, and geographic variations. The analysis used 2018 national survey data across 34 provinces, 513 cities/districts, and 300,000 households, with a sample of 73,864 women aged 10-54 years who have given birth in the preceding five years. The multilevel regression was used to assess the impact of social determinants and systemic inequalities on neonatal health. Key findings revealed a neonatal mortality rate that, despite being preventable in many cases, remained high with significant disparities. …


Telemedicine Adoption In Developing Economies: A Systematic Review On The Enablers And Barriers, Zaidbren Macabato, Lemuel Clark Velasco, Art Brian Escabarte, Mae-Lanie Ong Poblete, Armando Isla Jr., Rentor Cafino, Sarah Lizette Aquino-Cafino, Frevy Teofilo-Orencia Nov 2024

Telemedicine Adoption In Developing Economies: A Systematic Review On The Enablers And Barriers, Zaidbren Macabato, Lemuel Clark Velasco, Art Brian Escabarte, Mae-Lanie Ong Poblete, Armando Isla Jr., Rentor Cafino, Sarah Lizette Aquino-Cafino, Frevy Teofilo-Orencia

Kesmas

Telemedicine’s adoption has been effective in certain contexts despite being controversial in certain settings because of its tendency to cause misdiagnosis and concerns about data privacy. This study aimed to synthesize the research findings on the factors leading to the adoption of telemedicine among developing economies. The study utilized Preferred Reporting Items for Systematic Reviews and Meta-Analysis methodology to analyze 27 related literature and the Unified Theory of Acceptance and Use of Technology to map out the factors considered enablers and barriers in adopting telemedicine. Results showed that performance expectancy, effort expectancy, social influence, and facilitating conditions were significant predictors. …


Human Capital Assessment In Indigenous Regions To Enable Sustainable Futures, Victoria N. Sharakhmatova, Elena G. Mikhailova Nov 2024

Human Capital Assessment In Indigenous Regions To Enable Sustainable Futures, Victoria N. Sharakhmatova, Elena G. Mikhailova

Faculty Publications

This study is dedicated to the economic valuation of human capital (HC) in the regions where the Indigenous peoples of Kamchatka reside. The entire Kamchatksky Krai is considered an Indigenous people’s ancestral territory. However, in this study, only municipalities whose population is more than one-third Indigenous were chosen for the assessment. This includes six municipal districts and one urban district (Aleytsky, Bystrinsky, Karaginsky, Olyutorsky, Penzhinsky, and Tigilsky municipal districts and Palana urban district). The study employs statistical analysis and integrated, situational approaches: the investment approach was deemed the most appropriate tool for the economic assessment of HC in Indigenous territories. …


Strategies For Information Technology Managers To Mitigate Data Manipulation Challenges Within Healthcare Cloud, Oluwtosin Joseph Adeola Nov 2024

Strategies For Information Technology Managers To Mitigate Data Manipulation Challenges Within Healthcare Cloud, Oluwtosin Joseph Adeola

Walden Dissertations and Doctoral Studies

Healthcare information technology (IT) managers often lack effective protection strategies against cloud-based data manipulation, leaving their organizations vulnerable to significant financial, health, and privacy risks. Grounded in the technology threat avoidance theory, the purpose of this qualitative pragmatic inquiry was to explore strategies healthcare IT managers have to mitigate data manipulation that threatens data integrity related to the healthcare cloud. The participants were four IT managers of healthcare organizations in the Central Texas region of the United States who had strategies to mitigate data manipulation in the healthcare cloud. The data were collected using semistructured interviews and reviewing journals available …


Staff Education On Antihypertensive Medication Compliance Post-Stroke, Ernestina Serwaa Bonsu Nov 2024

Staff Education On Antihypertensive Medication Compliance Post-Stroke, Ernestina Serwaa Bonsu

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project was staff education to address the practice problem of staff knowledge deficit related to hypertensive medications compliance for post-stroke patients. The practice question was: Will staff education on antihypertensive medication compliance enhance nursing staff knowledge? It is essential to address the practice problem and question within the context of nursing practice because studies have shown that targeted nursing education promotes patient adherence. Participants were 42 nurses from neurology units who were evaluated before and after face-to-face education sessions. Nurses completed a pre-education survey questionnaire first, followed by education sessions and a post-education survey …


First Records Of The Spider Wasp Entypus Ochrocerus Dahlbom (Hymenoptera: Pompilidae: Pepsinae) From The Continental United States, Jamaica, And The Bahamas, Frank E. Kurczewski, Rick C. West, Dionne Newell, Scott Johnson Nov 2024

First Records Of The Spider Wasp Entypus Ochrocerus Dahlbom (Hymenoptera: Pompilidae: Pepsinae) From The Continental United States, Jamaica, And The Bahamas, Frank E. Kurczewski, Rick C. West, Dionne Newell, Scott Johnson

Insecta Mundi

A small population of Entypus ochrocerus Dahlbom, a predominantly Greater Antilles spider wasp (Hymenoptera: Pompilidae: Pepsinae), is reported for the first time from the continental United States based on photographs and associated information from iNaturalist.org. The species was initially misidentified online as E. unifasciatus unifasciatus (Say) or Entypus sp. However, Entypus u. unifasciatus individuals from east of the 100th Meridian in the United States typically have melanochromatic (dark) wings with a subapical xanthochromatic (orange-amber) patch. Entypus ochrocerus from Miami-Dade County, Florida is differentiated from E. u. unifasciatus by its black body with dark greenish blue reflections …


First Record Of The Camphor Shot Borer, Cnestus Mutilatus (Blandford) (Coleoptera: Curculionidae: Scolytinae), In Massachusetts, Lawrence E. Barringer Nov 2024

First Record Of The Camphor Shot Borer, Cnestus Mutilatus (Blandford) (Coleoptera: Curculionidae: Scolytinae), In Massachusetts, Lawrence E. Barringer

Insecta Mundi

Cnestus mutilatus (Blandford) (Coleoptera: Curculionidae: Scolytinae) is reported from Massachusetts, United States for the first time. Brief trapping information is provided.


Accumbal Plasticity And Associated Behavioral Adaptations In The Spared Nerve Injury Model Of Chronic Neuropathic Pain, Yu-Hsuan Chang Nov 2024

Accumbal Plasticity And Associated Behavioral Adaptations In The Spared Nerve Injury Model Of Chronic Neuropathic Pain, Yu-Hsuan Chang

Arts & Sciences Graduate Student Theses and Dissertations

Chronic pain is a debilitating neurological disorder that affects hundreds of millions of individuals worldwide. It is associated with cognitive symptoms such as cognitive inflexibility, which is defined as the inability to adaptively update behavior in response to changing environmental conditions. To date, there are no effective treatments for these symptoms, even though they substantially contribute to the decreased quality of life of chronic pain patients and are associated with reduced efficacy of pain management strategies. Therefore, understanding the neural circuit adaptations that drive cognitive symptoms of chronic pain, like cognitive inflexibility, is essential for improving existing treatments for this …


Harmony In Progress: Exploring Motivation’S Role In My Piano Learning And Practice Journey, Junyu Tao, Jane Southcott, Renee Crawford Nov 2024

Harmony In Progress: Exploring Motivation’S Role In My Piano Learning And Practice Journey, Junyu Tao, Jane Southcott, Renee Crawford

The Qualitative Report

This autoethnography explores the role of motivation in the piano learning and practice journey of the first author. The study is underpinned by understandings of how motivation evolves from extrinsic influences, such as parental support, teachers’ guidance, and peer influence, to intrinsic motivation that drives personal growth. Using a reflective and collaborative approach incorporating narratives, we examine key moments and emotional landscapes as the first author reveals the transformative power of motivation in shaping her piano learning experience. Our findings highlight the critical role of self-determination in fostering sustained engagement and success on the path of piano learning and practice. …


Site-Specific Prevalence Of Human Papillomavirus Infection In Malaysian Men, Mohd Khairul Anwar Shafii Nov 2024

Site-Specific Prevalence Of Human Papillomavirus Infection In Malaysian Men, Mohd Khairul Anwar Shafii

Student Works (2020-2029)

Human papillomavirus (HPV) infection is among one of the common infections among the female population and is closely associated with cervical cancer. It has gained attention since the introduction of prophylactic HPV vaccines. However, the epidemiology of HPV infection among the male population in the Asian context remains largely unknown. The worldwide report on the prevalence of HPV infection among men varies depending on the target population and method of sampling. This study aims to determine the knowledge, and site-specific prevalence of anogenital HPV infection, and its associated factors among sexually active men in an urban middle-income Asian setting. The …


Digging For Literature On Tailoring Cultural Offers With And For Older People From Ethnic Minority Groups: A Scoping Review, Stephanie Tierney, Jordan Gorenberg, Marta Santillo, Debra Westlake, Geoffrey Wong, Kerryn Husk, Sofia Vougioukalou, Ruthanne Baxter, Shoba Dawson, Nia Roberts, Caroline Potter, Harriet Warburton, Beth Mcdougall, Johannah Latchem, Kamal R Mahtani Nov 2024

Digging For Literature On Tailoring Cultural Offers With And For Older People From Ethnic Minority Groups: A Scoping Review, Stephanie Tierney, Jordan Gorenberg, Marta Santillo, Debra Westlake, Geoffrey Wong, Kerryn Husk, Sofia Vougioukalou, Ruthanne Baxter, Shoba Dawson, Nia Roberts, Caroline Potter, Harriet Warburton, Beth Mcdougall, Johannah Latchem, Kamal R Mahtani

Peninsula Medical School

INTRODUCTION: Social prescribing addresses non-medical issues (e.g., loneliness, financial worries, housing problems) affecting physical and/or mental health. It involves connecting people to external support or services, including 'cultural offers'-events, groups and activities run within or by cultural organisations. Such offers need to be acceptable and accessible to diverse populations if forming part of a social prescription.

METHODS: A scoping review was conducted to identify what existing literature, conducted in the United Kingdom, tells us about tailoring cultural offers for older people (aged 60+ years) from ethnic minority groups. Relevant literature was searched for on electronic databases, through Google, via a …


A Tetramer Of Bcl11a Is Required For Stable Protein Production And Fetal Hemoglobin Silencing, Ge Zheng, Maolu Yin, Stuti Mehta, I-Te Chu, Stacy Wang, Alia Alshaye, Kirstin Drainville, Altantsetseg Buyanbat, Frédérique Bienfait, Karin Tenglin, Qian Zhu, Stuart H Orkin Nov 2024

A Tetramer Of Bcl11a Is Required For Stable Protein Production And Fetal Hemoglobin Silencing, Ge Zheng, Maolu Yin, Stuti Mehta, I-Te Chu, Stacy Wang, Alia Alshaye, Kirstin Drainville, Altantsetseg Buyanbat, Frédérique Bienfait, Karin Tenglin, Qian Zhu, Stuart H Orkin

Faculty, Staff and Students Publications

Down-regulation of BCL11A protein reverses the fetal (HbF, α2γ2) to adult (HbA, α2β2) hemoglobin switch and is exploited in gene-based therapy for hemoglobin disorders. Due to reliance on ex vivo cell manipulation and marrow transplant, such therapies cannot lessen disease burden. To develop novel small molecule approaches, we interrogated the state of BCL11A protein in erythroid cells. We report that tetramer formation mediated by a single zinc-finger (ZnF0) is required for production of steady-state protein. Beyond its role in protein stability, the tetramer state is necessary for γ-globin gene repression, as an engineered monomer fails to engage a critical corepressor …


Maternal Low-Protein Diet Leads To Mitochondrial Dysfunction And Impaired Energy Metabolism In The Skeletal Muscle Of Male Rats, Vipin A Vidyadharan, Ancizar Betancourt, Craig Smith, Chellakkan S Blesson, Chandra Yallampalli Nov 2024

Maternal Low-Protein Diet Leads To Mitochondrial Dysfunction And Impaired Energy Metabolism In The Skeletal Muscle Of Male Rats, Vipin A Vidyadharan, Ancizar Betancourt, Craig Smith, Chellakkan S Blesson, Chandra Yallampalli

Faculty, Staff and Students Publications

A prenatal low-protein (LP) diet disrupts glucose homeostasis in adult offspring. Skeletal muscles are one of the main sites of glucose clearance, and mitochondria residing in the muscle fibers are central to glucose homeostasis. Our previous studies indicated that impaired mitochondrial health is central to dysregulated glucose metabolism in the gastrocnemius muscle of the LP-programmed female rats. In addition, dysfunctional mitochondria are often an indicator of underlying irregularities in energy metabolism and metabolic inflexibility. Therefore, this study examined the mitochondrial function and metabolic flexibility in the skeletal muscles of prenatal LP-programmed adult male rats. Pregnant Wistar rats were randomly allotted …


Maternal Low-Protein Diet Leads To Mitochondrial Dysfunction And Impaired Energy Metabolism In The Skeletal Muscle Of Male Rats, Vipin A Vidyadharan, Ancizar Betancourt, Craig Smith, Chellakkan S Blesson, Chandra Yallampalli Nov 2024

Maternal Low-Protein Diet Leads To Mitochondrial Dysfunction And Impaired Energy Metabolism In The Skeletal Muscle Of Male Rats, Vipin A Vidyadharan, Ancizar Betancourt, Craig Smith, Chellakkan S Blesson, Chandra Yallampalli

Faculty, Staff and Students Publications

A prenatal low-protein (LP) diet disrupts glucose homeostasis in adult offspring. Skeletal muscles are one of the main sites of glucose clearance, and mitochondria residing in the muscle fibers are central to glucose homeostasis. Our previous studies indicated that impaired mitochondrial health is central to dysregulated glucose metabolism in the gastrocnemius muscle of the LP-programmed female rats. In addition, dysfunctional mitochondria are often an indicator of underlying irregularities in energy metabolism and metabolic inflexibility. Therefore, this study examined the mitochondrial function and metabolic flexibility in the skeletal muscles of prenatal LP-programmed adult male rats. Pregnant Wistar rats were randomly allotted …


Legacy Effects Of Plant Community Structure Are Manifested In Microbial Biofilm Development With Consequences For Ecosystem Co Emissions, Kevin H. Wyatt, Jillian Cieslik, Catherine M. Dieleman, Evan Kane, Allison R. Rober, Barrett Sullivan, Merritt R. Turetsky Nov 2024

Legacy Effects Of Plant Community Structure Are Manifested In Microbial Biofilm Development With Consequences For Ecosystem Co Emissions, Kevin H. Wyatt, Jillian Cieslik, Catherine M. Dieleman, Evan Kane, Allison R. Rober, Barrett Sullivan, Merritt R. Turetsky

Michigan Tech Publications

To better understand linkages between hydrology and ecosystem carbon flux in northern aquatic ecosystems, we evaluated the relationship between plant communities, biofilm development, and carbon dioxide (CO) exchange following long-term changes in hydrology in an Alaskan fen. We quantified seasonal variation in biofilm composition and CO exchange in response to lowered and raised water table position (relative to a control) during years with varying levels of background dissolved organic carbon (DOC). We then used nutrient-diffusing substrates (NDS) to evaluate cause-effect relationships between changes in plant subsidies (i.e., leachates) and biofilm composition among water table treatments. We found that background DOC …


De-Identification Is Not Enough: A Comparison Between De-Identified And Synthetic Clinical Notes, Atiquer Rahman Sarkar, Yao-Shun Chuang, Noman Mohammed, Xiaoqian Jiang Nov 2024

De-Identification Is Not Enough: A Comparison Between De-Identified And Synthetic Clinical Notes, Atiquer Rahman Sarkar, Yao-Shun Chuang, Noman Mohammed, Xiaoqian Jiang

Faculty, Staff and Student Publications

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data generative models and the breakthroughs in large generative language models raise the question of whether synthetically generated clinical notes could be a viable alternative to real notes for research purposes. In this work, we demonstrated that (i) de-identification of real clinical notes does not protect records against a membership inference attack, (ii) proposed a novel approach to generate synthetic clinical notes using the current state-of-the-art large language models, (iii) evaluated …


“It’S Not Because They’Re Gypsy”: Practitioners Perspectives Of Gypsies, Travellers And Crime And Justice, Raegan Booth, Kirsty Koral, Kitty Lymperopoulou Nov 2024

“It’S Not Because They’Re Gypsy”: Practitioners Perspectives Of Gypsies, Travellers And Crime And Justice, Raegan Booth, Kirsty Koral, Kitty Lymperopoulou

School of Law, Humanities and Social Sciences

In dominant public, political and media narratives of Gypsy and Traveller communities, they have often been associated with criminality, deviance, violence, idleness and reluctance to assimilate into settled society. A discourse of othering predicated on negative stereotypes further affect their marginalisation and social exclusion. This empirical article critically examines reflections on, and responses to, these dominant narratives among practitioners who have engaged with Gypsy and Travellers operationally and strategically, in relation to crime and criminal justice. We find evidence of compliance with dominant narratives which include perceptions that deny and minimise experiences of victimisation and racism, while also suggesting a …


Heart Failure Beyond The Diagnosis: A Narrative Review Of Patients' Perspectives On Daily Life And Challenges, Michelle Shigi Yang, Mohamed Bilal Abdallah, Zubair Bashir, Wissam Khalife Nov 2024

Heart Failure Beyond The Diagnosis: A Narrative Review Of Patients' Perspectives On Daily Life And Challenges, Michelle Shigi Yang, Mohamed Bilal Abdallah, Zubair Bashir, Wissam Khalife

Faculty, Staff and Student Publications

Heart failure (HF) is a complex syndrome that significantly affects patients' physical, psychological, and socioeconomic well-being. Despite advances in guideline-directed medical therapy (GDMT), such as ACE inhibitors, beta-blockers, and SGLT2 inhibitors, HF continues to have a high global burden, with over 64 million affected worldwide and a five-year mortality rate of 50%. HF disrupts various life aspects, especially for younger patients (aged 35-55), who often face career interruptions due to severe symptoms like fatigue and frequent hospitalizations. These patients may struggle to maintain employment, resulting in financial instability compounded by high healthcare costs. Moreover, reduced exercise capacity and sexual dysfunction …


Improved Health At The United States-Mexican Border: A Case Study, Janet B. Snyder Nov 2024

Improved Health At The United States-Mexican Border: A Case Study, Janet B. Snyder

The Geographical Bulletin

Improved Health at the United States-Mexican Border: A Case Study


Alone With Wolves: Gudrun Pflueger Believes That A Buried Instinct To Handle Predators Saved Her In A Wilderness Meadow, Christine Woodside Nov 2024

Alone With Wolves: Gudrun Pflueger Believes That A Buried Instinct To Handle Predators Saved Her In A Wilderness Meadow, Christine Woodside

Appalachia

No abstract provided.


Grizzly Fear: There Is A Difference Between Ignorance And Wary Respect For A Creature Of Several Reputations, Jeff Fair Nov 2024

Grizzly Fear: There Is A Difference Between Ignorance And Wary Respect For A Creature Of Several Reputations, Jeff Fair

Appalachia

No abstract provided.


Appalachia Winter/Spring 2009: Complete Issue Nov 2024

Appalachia Winter/Spring 2009: Complete Issue

Appalachia

Winter/Spring 2009 - Volume LX, Number 1 - issue #227. What are we afraid of? Facing up to grizzlies, ghosts, wolves, crevasses—and ourselves.


Return To The Mountain Ridge Of Our Lives: Eight Years After Her Husband Died On Mount Lafayette, A Writer Returns To A Place That Was Like An Extension Of Her Backyard, Laura Waterman Nov 2024

Return To The Mountain Ridge Of Our Lives: Eight Years After Her Husband Died On Mount Lafayette, A Writer Returns To A Place That Was Like An Extension Of Her Backyard, Laura Waterman

Appalachia

No abstract provided.


The White Mountains, By Train: Lower Speeds, Longer Vacations, Andrew Riely Nov 2024

The White Mountains, By Train: Lower Speeds, Longer Vacations, Andrew Riely

Appalachia

No abstract provided.


Appalachia Summer/Fall 2009: Complete Issue Nov 2024

Appalachia Summer/Fall 2009: Complete Issue

Appalachia

Summer/Fall 2009 - Volume LX, Number 2 - issue #228. Our carbon footprint: Old and new pathways to the mountains.


Recognition Or Refusal? Marginalized Identity Development In Passing And The Color Purple, Lee M. Kassay Nov 2024

Recognition Or Refusal? Marginalized Identity Development In Passing And The Color Purple, Lee M. Kassay

Theses & Honors Papers

The novels Passing by Nella Larsen and The Color Purple by Alice Walker both involve identity development in their black queer female protagonists, but previous scholarship has rarely discussed the works in tandem. Thus, I merge the discussion around these two works by analyzing them through the concept of G.W.F. Hegel's master-slave dialectic. Assessing how both protagonists participate in their relationships with their female love interests versus their male husbands shows the importance of mutual recognition in the development of identity.


Soil Biogeography And Community Assembly In Polar Regions, Jesse Jorna Nov 2024

Soil Biogeography And Community Assembly In Polar Regions, Jesse Jorna

Theses and Dissertations

The polar regions provide community ecologists with natural microcosms, that include reduced species diversity, steep environmental gradients and limited human perturbance. Soil biodiversity in the polar regions is poorly understood, and the driving forces behind community compositions can range in scale from glacial forces 20,000 years ago to the impact of a researcher's footstep. Here, we present the results of an investigation of the driving factors behind biodiversity in Arctic and Antarctic soils, with specific attention to the role of community assembly processes. We suggest a framework for investigating the effects of inter-bacterial community processes like facilitation and argue for …


Strprofiler: Efficient Comparisons Of Short Tandem Repeat Profiles For Biomedical Model Authentication., Jared M Andrews, Michael W Lloyd, Steven Neuhauser, Margaret Bundy, Emily L Jocoy, Susan Airhart, Carol J Bult, Yvonne A Evrard, Jeffrey Chuang, Suzanne Baker Nov 2024

Strprofiler: Efficient Comparisons Of Short Tandem Repeat Profiles For Biomedical Model Authentication., Jared M Andrews, Michael W Lloyd, Steven Neuhauser, Margaret Bundy, Emily L Jocoy, Susan Airhart, Carol J Bult, Yvonne A Evrard, Jeffrey Chuang, Suzanne Baker

Faculty Research 2024

SUMMARY: Short tandem repeat (STR) profiling is commonly performed for authentication of biomedical models of human origin, yet no tools exist to easily compare sets of STR profiles to each other or an existing database in a high-throughput manner. Here, we present STRprofiler, a Python package, command line tool, and Shiny application providing methods for STR profile comparison and cross-contamination detection. STRprofiler can be run with custom databases or used to query against the Cellosaurus cell line database.

AVAILABILITY AND IMPLEMENTATION: STRprofiler is freely available as a Python package with a rich CLI from PyPI https://pypi.org/project/strprofiler/ with source code available …