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2024

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Retirement And Life Satisfaction Among Middle-Aged And Older Adults: A Piecewise Growth Mixture Analysis, Jonathan L. Chia, Andree Hartanto, William Tov Aug 2024

Retirement And Life Satisfaction Among Middle-Aged And Older Adults: A Piecewise Growth Mixture Analysis, Jonathan L. Chia, Andree Hartanto, William Tov

Research Collection School of Social Sciences

Retirement represents a significant life transition typically occurring in later adulthood, often accompanied by substantial lifestyle changes. Several theoretical frameworks suggest that these changes present both opportunities and challenges for well-being, and the extent to which individuals experience positive versus negative well-being outcomes may be influenced by various factors. To study such heterogeneity in retirement experiences, researchers have embraced person-centered methodologies. Yet, some previous studies have not robustly delineated retirement- from age-related changes in well-being, accounted for statistical uncertainties, or examined these diverse experiences outside of a Western context. These limitations preclude conclusions about the diverse experience of retirement. Using …


The Impact Of Sense Of Loneliness On Geriatric Depression: The Mediating Role Of Sense Of Mattering And Psychological Adjustment Download Pdf, Haya K. Aman Ms. Aug 2024

The Impact Of Sense Of Loneliness On Geriatric Depression: The Mediating Role Of Sense Of Mattering And Psychological Adjustment Download Pdf, Haya K. Aman Ms.

psychology

Background

Depression is a highly prevalent mental disorder in older adults, and among its highest risk factors is loneliness. Although this relationship is commonly evident, the mechanisms underlying it, such as sense of mattering and psychological adjustment, lack exploration. The current research aims to examine the relationship between loneliness and geriatric depression and explore the mediating roles of sense of mattering and psychological adjustment.

Methods

A sample of 200 older adults (63.5% females; mean age = 75.6; SD = 8.806) were recruited from 24 geriatric homes in Cairo, Egypt. Participants responded to the Arabic versions of the Mini-Mental State Examination …


Political Constructions Of People Who Use Drugs In The Philippines: A Qualitative Content Analysis, Gideon Lasco Aug 2024

Political Constructions Of People Who Use Drugs In The Philippines: A Qualitative Content Analysis, Gideon Lasco

Development Studies Faculty Publications

Background

This paper examines the political constructions of people who use drugs in the Philippines throughout the presidency of Rodrigo Duterte (2016–2022), during which the government engaged in a ‘war on drugs’ and promoted a punitive drug regime.

Methods

Building on and drawing inspiration from the global drug policy scholarship that has looked at the ways in which drugs are framed and problematised in various domains, this study used qualitative content analysis to review 96 documents from national government agencies - including strategic action plans, directives, memorandums, guidelines, annual reports, and legislative measures.

Results

Foremost, the study finds that various …


The Role Of Cognitive Dysfunction In Late-Life Depression, Matthew Schurr Aug 2024

The Role Of Cognitive Dysfunction In Late-Life Depression, Matthew Schurr

UNLV Theses, Dissertations, Professional Papers, and Capstones

Depression is one of the most common psychiatric concerns in older adults. Because of the intersection of biological, emotional, social, and cognitive factors that are at play in depression, symptoms are often heterogeneous in presence and severity. In combination with the expected changes in cognitive abilities as one ages, late-life depression can be additive to these changes. The higher risks of neurodegenerative processes and vascular events in later life can cause, magnify, or accelerate cognitive decline. As such, individuals with late-life depression often present with a complex array of problems that can impact cognition and functioning, and thus complicate the …


A Comparison Of Training Approaches On Skill Acquisition Among Direct Care Staff At An Adult Day Program, Sandra Wagner Aug 2024

A Comparison Of Training Approaches On Skill Acquisition Among Direct Care Staff At An Adult Day Program, Sandra Wagner

Dissertations

Adults with intellectual and developmental disabilities (IDD) are often dependent on direct care staff to engage in daily activities, such as personal care, eating, and engaging in leisure activities. One way direct care staff can support adults with IDD to become more independent is by using prompting strategies. Often times, however, direct care staff have not been trained on how to use prompts to encourage independence. Current studies have demonstrated success in teaching direct care staff prompting strategies in personal care tasks (e.g., Engelman et al., 2002; Parsons et al., 1993) through behavioral skills training. Although the trainings produced an …


University Of Central Florida Undergraduate Catalog, 2024 - 2025, University Of Central Florida Aug 2024

University Of Central Florida Undergraduate Catalog, 2024 - 2025, University Of Central Florida

UCF Catalogs

No abstract provided.


Covering The Care: Most Prevalent Health Conditions And Their Associated Costs Among Nh’S Insured Population – Behavioral Health And Cardiovascular Disease Top The List, Bethany Swanson, Erica Plante, Deborah Fournier Aug 2024

Covering The Care: Most Prevalent Health Conditions And Their Associated Costs Among Nh’S Insured Population – Behavioral Health And Cardiovascular Disease Top The List, Bethany Swanson, Erica Plante, Deborah Fournier

Faculty Publications

This data brief presents an analysis of available claims data from New Hampshire’s commercial, Medicaid, and Medicare insured populations. Specifically, the study identifies the top ten most prevalent health conditions, the cost of treatment for those conditions, and the overall medical cost for those with one of the identified conditions. The analysis is based on the most recent calendar year of available claims data (January – December 2022).


Acute Effects Of Multi-Joint Eccentric Exercise On Lower Extremity Muscle Activation Measured During Land And Water Walking, Brayden Worley Aug 2024

Acute Effects Of Multi-Joint Eccentric Exercise On Lower Extremity Muscle Activation Measured During Land And Water Walking, Brayden Worley

All Graduate Reports and Creative Projects, Fall 2023 to Present

Although prior literature has established the preliminary clinical benefits of aquatic exercise across various clinical populations, there is a need to explore the potential for including aquatic-based movement as a key component of a multi-modal approach toward improving mobility and reducing fall risk. Eccentric exercise may complement aquatic exercise given that movements performed in water immersion tend to be low impact. Eccentric exercise may also improve the passive stiffness of lower extremity extensors, which gives an additional rationale for the potential of eccentric exercise to reduce fall risk when combined with aquatic exercise. There may also be an acute response …


Exploring Telehealth Utilization Through Data Analytics, Statistical Analyses, And Machine Learning Techniques, Aysenur Betul Cengil Aug 2024

Exploring Telehealth Utilization Through Data Analytics, Statistical Analyses, And Machine Learning Techniques, Aysenur Betul Cengil

Graduate Theses and Dissertations

This dissertation investigates the utilization of telehealth services, initially focusing on the Arkansas healthcare system and then extending the analysis nationwide. It aims to understand the factors influencing telehealth adoption and its impact on healthcare delivery. After examining telehealth utilization in Arkansas from 2018 to 2022, the research utilizes a comprehensive dataset from Epic Cosmos, which includes a wide range of patient and visit data from multiple healthcare facilities across the United States from 2018 to 2023. This timeframe allows for a detailed analysis of telehealth trends before, during, and after the COVID-19 pandemic. In Chapter 2, we analyze key …


Assessing Sarcopenia In Advanced-Stage Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Case Series, Christelle Schofield, Dennis R. Taaffe, Robert U. Newton, Daniel A. Galvão, Paul A. Cohen, Jin Soo Kim, Tarek Meniawy, Carolyn Peddle-Mcintyre Aug 2024

Assessing Sarcopenia In Advanced-Stage Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Case Series, Christelle Schofield, Dennis R. Taaffe, Robert U. Newton, Daniel A. Galvão, Paul A. Cohen, Jin Soo Kim, Tarek Meniawy, Carolyn Peddle-Mcintyre

Research outputs 2022 to 2026

Objectives: In ovarian and other cancers, low muscle mass and density are associated with poorer clinical outcomes. However, screening for cancer-related sarcopenia (typically defined as low muscle mass) is not routinely conducted. The European Working Group on Sarcopenia in Older People (EWGSOP) recommends an algorithm for sarcopenia screening and diagnosis in clinical settings, with sarcopenia based on muscle strength and mass, and severity on physical performance. We explored the application of the EWGSOP2 algorithm to assess sarcopenia in six ovarian cancer patients receiving neoadjuvant chemotherapy. Methods: We assessed sarcopenia risk with the SARC-F screening questionnaire (at risk ≥4 points), muscle …


Apolipoprotein Ε4 Is Associated With Increased Risk Of Fall- And Fracture-Related Hospitalization: The Perth Longitudinal Study Of Ageing Women, Jedd Pratt, Jack Dalla Via, Craig Sale, Abadi K. Gebre, Blossom C.M. Stephan, Simon Laws, Kun Zhu, Wai H. Lim, Richard L. Prince, Joshua R. Lewis, Marc Sim Aug 2024

Apolipoprotein Ε4 Is Associated With Increased Risk Of Fall- And Fracture-Related Hospitalization: The Perth Longitudinal Study Of Ageing Women, Jedd Pratt, Jack Dalla Via, Craig Sale, Abadi K. Gebre, Blossom C.M. Stephan, Simon Laws, Kun Zhu, Wai H. Lim, Richard L. Prince, Joshua R. Lewis, Marc Sim

Research outputs 2022 to 2026

Apolipoprotein ε4 (APOE ε4) may be a genetic risk factor for reduced bone mineral density (BMD) and muscle function, which could have implications for fall and fracture risk. We examined the association between APOE ε4 status and long-term fall- and fracture-related hospitalization risk in older women. A total of 1 276 community-dwelling women from the Perth Longitudinal Study of Aging Women (mean age ± SD = 75.2 ± 2.7 years) were included. At baseline, women underwent APOE genotyping and detailed phenotyping for covariates including prevalent falls and fractures, as well as health and lifestyle factors. The association between APOE ε4 …


Neurocognitive Functioning In Adults With Trichotillomania: Predictors Of Treatment Response And Symptom Severity In A Randomized Control Trial, Kathryn E. Barber, Douglas W. Woods, Thilo Deckersbach, Christopher C. Bauer, Scott N. Compton, Michael P. Twohig, Emily J. Ricketts, Jordan Robinson, Stephen M. Saunders, Martin E. Franklin Aug 2024

Neurocognitive Functioning In Adults With Trichotillomania: Predictors Of Treatment Response And Symptom Severity In A Randomized Control Trial, Kathryn E. Barber, Douglas W. Woods, Thilo Deckersbach, Christopher C. Bauer, Scott N. Compton, Michael P. Twohig, Emily J. Ricketts, Jordan Robinson, Stephen M. Saunders, Martin E. Franklin

Psychology Faculty Research and Publications

Trichotillomania (TTM) is associated with impairments in response inhibition and cognitive flexibility, but it is unclear how such impairments relate to treatment outcome. The present study examined pre-treatment response inhibition and cognitive flexibility as predictors of treatment outcome, change in these domains from pre-to post-treatment, and associations with TTM severity. Participants were drawn from a randomized controlled trial comparing acceptance-enhanced behavior therapy (AEBT) to psychoeducation and supportive therapy (PST) for TTM. Adults completed assessments at pre-treatment (n = 88) and following 12 weeks of treatment (n = 68). Response inhibition and cognitive flexibility were assessed using the Stop …


Comorbid Dementia And Cancer Therapy Decision-Making: A Scoping Review, Sean N. Halpin, Gabriel Alain, Aaron Seaman, Erin E. Stevens, Hui Zhao, Mackenzie E. Fowler, Qiuyang Zhang, Tamara Cadet, Minzhi Ye, Jessica L. Krok-Schoen Aug 2024

Comorbid Dementia And Cancer Therapy Decision-Making: A Scoping Review, Sean N. Halpin, Gabriel Alain, Aaron Seaman, Erin E. Stevens, Hui Zhao, Mackenzie E. Fowler, Qiuyang Zhang, Tamara Cadet, Minzhi Ye, Jessica L. Krok-Schoen

School of Social Work Faculty Publications

Comorbid dementia complicates cancer therapy decision-making in older adults. We aimed to synthesize the recent literature (< 5 >years) on the challenges associated with cancer therapy decision-making among older people living with dementia (PLWD) and their caregivers. Of the 20,763 references, 8767 had their title and abstract screened, and eight met the inclusion criteria. Six studies were qualitative, one study employed mixed methods, and one study was quasi-experimental. Most studies were conducted in the UK (89%) and reported homogeneity in race and geography. Breast (56%) and prostate (45%) were the most frequent reported cancers. Five studies (56%) reported multiple types of …


Promoting Cultural Humility, Belonging, And Inclusion To Improve Well-Being Among Direct Care Staff In Oregon Assisted Living, Residential Care, And Memory Care Communities, 2024, Jacklyn Kohon, Dani Himes, Laura Rodriguez, Sarah Dys, Paula Carder, Diana Jacoby, Madeline Fox Aug 2024

Promoting Cultural Humility, Belonging, And Inclusion To Improve Well-Being Among Direct Care Staff In Oregon Assisted Living, Residential Care, And Memory Care Communities, 2024, Jacklyn Kohon, Dani Himes, Laura Rodriguez, Sarah Dys, Paula Carder, Diana Jacoby, Madeline Fox

Institute on Aging Publications

The voices and experiences of those working and living in assisted living, residential care, and memory care (AL/RC) settings in Oregon are highlighted in this study to understand cultural humility, belonging, inclusion, and intersectional experiences related to sustaining the workforce and promoting quality care. This qualitative study collected data through individual and focus group interviews with a total of 68 people, including 25 direct care staff, voice memos or interviews with 9 former direct care staff, interviews with 9 administrators, interviews with 7 management representatives (owner/operators, human resources specialists, directors of operations, among other titles), and interviews with 18 current …


Climate And Extreme Weather Event Impacts On Administrators, Direct Care Staff, And Residents In Oregon Assisted Living, Residential Care, And Memory Care Communities, 2024, Dani Himes, Jacklyn Kohon, Madeline Fox, Laura Rodriguez, Sarah Dys, Diana Jacoby, Paula Carder Aug 2024

Climate And Extreme Weather Event Impacts On Administrators, Direct Care Staff, And Residents In Oregon Assisted Living, Residential Care, And Memory Care Communities, 2024, Dani Himes, Jacklyn Kohon, Madeline Fox, Laura Rodriguez, Sarah Dys, Diana Jacoby, Paula Carder

Institute on Aging Publications

This brief report on AL/RC staff and resident experiences with climate events highlights the voices of AL/RC direct care staff, former direct care staff, residents, administrators, and management representatives to promote well-being in these care settings. This study can inform Oregon’s efforts to support long-term care workforce readiness for future climate emergencies and inform future quantitative data collection on AL/RC and other long-term care workers, including those employed in home health agencies, nursing facilities, and adult foster homes.


A Protocol For The Inclusion Of Minoritized Persons In Alzheimer Disease Research From The Adni3 Diversity Taskforce, Ozioma C Okonkwo, Beau M Ances, Et Al. Aug 2024

A Protocol For The Inclusion Of Minoritized Persons In Alzheimer Disease Research From The Adni3 Diversity Taskforce, Ozioma C Okonkwo, Beau M Ances, Et Al.

2020-Current year OA Pubs

IMPORTANCE: Black or African American (hereinafter, Black) and Hispanic or Latino/a/x (hereinafter, Latinx) adults are disproportionally affected by Alzheimer disease, but most research studies do not enroll adequate numbers of both of these populations. The Alzheimer's Disease Neuroimaging Initiative-3 (ADNI3) launched a diversity taskforce to pilot a multipronged effort to increase the study inclusion of Black and Latinx older adults.

OBJECTIVE: To describe and evaluate the culturally informed and community-engaged inclusion efforts to increase the screening and enrollment of Black and Latinx older adults in ADNI3.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used baseline data from a longitudinal, multisite, …


Associations Of Mid-To-Late-Life Inflammation With Late-Life Mobility And The Influences Of Chronic Comorbidities, Race, And Social Determinants Of Health: The Atherosclerosis Risk In Communities Study, Kirby G Parker, B Gwen Windham, Chad Blackshear, Keenan A Walker, Sara B Parker, Ron C Hoogeveen, Christie M Ballantyne, Anna Kucharska-Newton, Priya Palta, Elizabeth Selvin, Maria Vassilaki, Thomas H Mosley, Michael E Griswold Aug 2024

Associations Of Mid-To-Late-Life Inflammation With Late-Life Mobility And The Influences Of Chronic Comorbidities, Race, And Social Determinants Of Health: The Atherosclerosis Risk In Communities Study, Kirby G Parker, B Gwen Windham, Chad Blackshear, Keenan A Walker, Sara B Parker, Ron C Hoogeveen, Christie M Ballantyne, Anna Kucharska-Newton, Priya Palta, Elizabeth Selvin, Maria Vassilaki, Thomas H Mosley, Michael E Griswold

Faculty, Staff and Students Publications

Background: Relationships of midlife inflammation with late-life mobility and influences of chronic health conditions, race, and social determinants of health (SDoH) on these relationships are poorly understood.

Methods: Among 4758 community-dwelling participants (41% men, 20% Black), high-sensitivity C-reactive protein (hsCRP) was measured over 20+ years: in midlife at study visit 2 (V2: 1990-1992, 47-68 years); at V4 (1996-1998, 53-74 years); and with concurrent late-life 4-m gait speed at V5 (2011-2013, 67-88 years, mean 75 years). SDoH measures included race, the national-rank area deprivation index, education, and income. We examined associations of late-life gait speed with midlife hsCRP (V2 continuous and …


Age-Related Dysregulation Of The Retinal Transcriptome In African Turquoise Killifish, Steven Bergmans, Nicole C L Noel, Luca Masin, Ellen G Harding, Aleksandra M Krzywańska, Julie D De Schutter, Rajagopal Ayana, Chi-Kuo Hu, Lut Arckens, Philip A Ruzycki, Ryan B Macdonald, Brian S Clark, Lieve Moons Aug 2024

Age-Related Dysregulation Of The Retinal Transcriptome In African Turquoise Killifish, Steven Bergmans, Nicole C L Noel, Luca Masin, Ellen G Harding, Aleksandra M Krzywańska, Julie D De Schutter, Rajagopal Ayana, Chi-Kuo Hu, Lut Arckens, Philip A Ruzycki, Ryan B Macdonald, Brian S Clark, Lieve Moons

2020-Current year OA Pubs

Age-related vision loss caused by retinal neurodegenerative pathologies is becoming more prevalent in our ageing society. To understand the physiological and molecular impact of ageing on retinal homeostasis, we used the short-lived African turquoise killifish, a model known to naturally develop central nervous system (CNS) ageing hallmarks and vision loss. Bulk and single-cell RNA-sequencing (scRNAseq) of three age groups (6-, 12-, and 18-week-old) identified transcriptional ageing fingerprints in the killifish retina, unveiling pathways also identified in the aged brain, including oxidative stress, gliosis, and inflammageing. These findings were comparable to observations in the ageing mouse retina. Additionally, transcriptional changes in …


“It Was Difficult To Understand The System”: Developing A Coordinator Role To Support International Nursing Students- A Qualitative Study Aug 2024

“It Was Difficult To Understand The System”: Developing A Coordinator Role To Support International Nursing Students- A Qualitative Study

Journal of Comparative & International Higher Education

No abstract provided.


Grievability And The Contingency Of Life Value In Twenty-First-Century Science Fiction, Emily A. Reiff Jul 2024

Grievability And The Contingency Of Life Value In Twenty-First-Century Science Fiction, Emily A. Reiff

English Language and Literature ETDs

Using Judith Butler’s framework of grievability, this dissertation explores twenty-first-century science fiction by British, Irish, and Caribbean authors whose novels grapple with legacies of colonialism and imperialism that relied on dehumanization and subjugation. Beginning with Sarah Maria Griffin’s Spare and Found Parts (2016), chapter one explores neocolonial rationales—purportedly based on health—which recreate colonial divisions of class and labor and enforce systems of diminishing grievability in a post-apocalyptic Irish context. Chapter two contends that Kazuo Ishiguro’s Klara and the Sun (2021) illustrates the danger inherent to value systems that center “normative” embodiment in worlds that reconfigure hypercapacitated human beings as the …


Caring, 1994 Summer, Advocate Health - Midwest Jul 2024

Caring, 1994 Summer, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue highlights several of the medical center's programs, including its Babycheck program, the Warren Barr Pavilion's adult day services, the antenatal resource center, Hispanocare, and Healthcare for the Homeless.


Caring, 1999 Winter, Advocate Health - Midwest Jul 2024

Caring, 1999 Winter, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue has feature stories on HIV/AIDS inpatient care, advanced practice nursing, and an intergenerational program of middle school students and elderly residents at the Warren Barr Pavilion.


Caring, 1987 Winter, Advocate Health - Midwest Jul 2024

Caring, 1987 Winter, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This is the first issue of "Caring" in its revised format. This issue has feature stories on the Ruth M. Seay Center for Women and Infants - a new state-of-the-art obstetrics unit, the emergency department's level 1 trauma center, and the White Crane Senior Health Center.

This is the first issue the library has in the new format. The last issue the library has in the previous version of this publication can be seen here: Caring, 1980 V4 N3, Fall/Winter


Frailty Explains Variation In Emergency Department Use For Older Veterans During The Covid-19 Pandemic, Justine Seidenfeld, Karen M. Stechuchak, Valerie A. Smith, Catherine Stanwyck, Chelsea Perfect, Courtney Van Houtven, Susan Nicole Hastings Jul 2024

Frailty Explains Variation In Emergency Department Use For Older Veterans During The Covid-19 Pandemic, Justine Seidenfeld, Karen M. Stechuchak, Valerie A. Smith, Catherine Stanwyck, Chelsea Perfect, Courtney Van Houtven, Susan Nicole Hastings

Journal of Geriatric Emergency Medicine

Background: Older adults were critically vulnerable to disruptions in health care during the COVID-19 pandemic, but it is not known if changes in ED utilization varied based on patient characteristics. Using a cohort of older Veterans, we examined changes in ED visit rates based on four characteristics of interest: age, race, area deprivation index, and frailty

Methods: Participants were aged ≥65, with ≥2 visits in primary or geriatric clinics between 02/02/2018-05/07/2019. An adjusted negative binomial regression model was constructed for each characteristic. We report mean counts of all ED visits by quarter for subgroups separately, and report rate …


Impacts Of Social Media Use On The Wellbeing Of Older Adults : Evidence From China During The Covid-19 Pandemic, Xuying Dong Jul 2024

Impacts Of Social Media Use On The Wellbeing Of Older Adults : Evidence From China During The Covid-19 Pandemic, Xuying Dong

Lingnan Theses (Doctoral degree)

Given the trend of increasing use of information and communication technologies among Chinese elder population, more attention should be drawn on the relationship between social media use and wellbeing of older adults. This research explores the social media use situation among older adults in mainland China as well as its influences on their wellbeing, and employs a mixed approach including quantitative questionnaire distributed via WeChat social media platform and qualitative interview among Chinese older adults who are over 60 years of age in Jingzhou, Hubei Province. Generally speaking, social media use can improve the wellbeing of Chinese older adults, more …


Aging As Online Faculty: Attitudes Toward Work And Retirement, Lee Stadtlander, Amy Sickel Jul 2024

Aging As Online Faculty: Attitudes Toward Work And Retirement, Lee Stadtlander, Amy Sickel

Journal of Educational Research and Practice

Aging, an often-neglected aspect of diversity in universities, is an important issue, as the rate of people working who are 75 and older is growing faster than the rate for any other age group. The present sequential explanatory mixed-method study explored 129 older online faculty’s attitudes and opinions on work and retirement in an online survey and in 13 faculty interviews. Data were examined cross-sectionally to assess differences by decade: 50s, 60s, and 70s and above. The results indicated that while older faculty were collecting some form of retirement payment, money was not a primary motivator for working. These individuals …


Factors Related To Physical Activity Of Patients With Permanent Cardiac Pacemaker, Priyaporn Phruksahiran, Noraluk Ua-Kit Jul 2024

Factors Related To Physical Activity Of Patients With Permanent Cardiac Pacemaker, Priyaporn Phruksahiran, Noraluk Ua-Kit

Chulalongkorn Medical Journal

Background: Over 1.3 million patients worldwide have permanent cardiac pacemakers (PPM). Patients with PPM, in the first to third months after implantation, still report problems with physical activity (PA), such as limitations in their lives, jobs, and exercise, inability to perform activities as before, and decreased PA.

Objectives: This study aimed to investigate the PA of patients with PPM and identify factors (age, perceived self-efficacy, perceived benefits, perceived barriers, social support, and health literacy) related to the PA of patients with PPM.

Methods: This descriptive-correlational study included 110 male and female patients with PPM from three tertiary hospitals in …


Monoclonal Antibodies For The Treatment Of Prodromal Alzheimer’S Disease, Katrina Grunst Jul 2024

Monoclonal Antibodies For The Treatment Of Prodromal Alzheimer’S Disease, Katrina Grunst

Summer Interdisciplinary Research Symposium

Objective: Alzheimer’s disease presents a significant public health problem, characterized by a progressive loss of cognitive functioning ability, ultimately leading to severe dementia and loss of basic motor functions. With these patients accounting for a large percentage of hospital stays and healthcare expenditures, the urgency to address this disease is evident, particularly considering the projected growth of the aging population. This paper aims to explore new drug treatments that may alter the underlying process of Alzheimer’s disease and potentially prevent cognitive decline in future generations. Methods: Through a comprehensive review of studies examining monoclonal antibody drugs including aducanumab, lecanemab, and …


Perceptions Of Graduate Nurse Practitioner Faculty On The Use Of Simulation In Lieu Of Traditional Clinical Hours, Virginia Strong Jul 2024

Perceptions Of Graduate Nurse Practitioner Faculty On The Use Of Simulation In Lieu Of Traditional Clinical Hours, Virginia Strong

Dissertations

Simulation in undergraduate nursing curriculum has been identified as an effective and safe substitution for the traditional clinical experience; however, graduate nurse education programs could not substitute clinical hours with simulation-based education. These clinical hours required NP students to provide direct face-to-face patient care. Simulation had wide variability in the number of hours utilized within each specialty. NONPF discussed the use of simulation, as it pertains to the curriculum of the NP student on more than one occasion and concluded its impact on NP education was a potential alternative to traditional clinical experiences. Studies indicated that graduate nursing students enjoy …


Comments Re: Draft Nih Intramural Research Program Policy: Promoting Equity Through Access Planning, Fred Ledley M.D., Edward Zhou Pharmd., Paula Chaves Da Silva Ph.D. Jul 2024

Comments Re: Draft Nih Intramural Research Program Policy: Promoting Equity Through Access Planning, Fred Ledley M.D., Edward Zhou Pharmd., Paula Chaves Da Silva Ph.D.

CISI Publication

We commend the NIH initiative to require that licensees of technologies that enable discovery or development of FDA-approved products arising from the NIH intramural program to include an Access Plan to promote “product affordability, availability, acceptability, and sustainability” and recognition that such protections are essential to ensuring a “return on taxpayers' investment in biomedical research.” Recognizing the complexity of anticipating appropriate terms for products that are in pre-clinical or early clinical development at the time of licensing, we also support the proposal that the Access Plan be submitted in late-stage clinical development, though we argue that …