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2024

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Centering Climate Science In Learning, Déana Scipio, Priya Pugh, Kali Natarajan, Deb L. Morrison, Bethany Kogut, Karli Honebein, Michelle Grove, Jen Eklund Jan 2024

Centering Climate Science In Learning, Déana Scipio, Priya Pugh, Kali Natarajan, Deb L. Morrison, Bethany Kogut, Karli Honebein, Michelle Grove, Jen Eklund

Climate, Water, and the Environment Research

The Washington State ClimeTime Network has been designed to build capacity for climate science learning, as well as broader NGSS implementation. As a network, we acknowledge the diversity of scientific histories and practices and continue to explore these variations to deepen our teaching and learning of climate science. This paper provides visions of what we mean by climate science centered learning, principles for fostering climate science learning, and guidance for capacity-building to achieve systemic implementation of climate science learning.


Heritage Values And Community Perception : A Look Into The Historic Ruins Of Dinajpur Rajbari, Murchana Madhury, Labanya Sarker Jan 2024

Heritage Values And Community Perception : A Look Into The Historic Ruins Of Dinajpur Rajbari, Murchana Madhury, Labanya Sarker

NAKHARA (Journal of Environmental Design and Planning)

The establishment of the value and effective protection of historical ruins comprises a subject of rising interest, as evidenced by an increasing amount of research involving several disciplines. In Bangladesh, debates on the relevance of such abandoned, degraded, deformed, or empty structures—unlike other intact monuments in heritage studies—rarely take into account the attitude of the locals towards these ruins. Analyzing the case of Dinajpur Rajbari, Bangladesh, the paper intends to explore the value ascribed to historic ruins by the surrounding community. The study uses a case study approach built on Mason’s value typology, which has widely contributed to the identification …


Lithium And Water: Hydrosocial Impacts Across The Life Cycle Of Energy Storage, James J.A. Blair, Noel Vineyard, Dustin Mulvaney, Alida Cantor, Ali Sharbat, Kate Berry, Elizabeth Bartholomew, Ariana Firebaugh Ornelas Jan 2024

Lithium And Water: Hydrosocial Impacts Across The Life Cycle Of Energy Storage, James J.A. Blair, Noel Vineyard, Dustin Mulvaney, Alida Cantor, Ali Sharbat, Kate Berry, Elizabeth Bartholomew, Ariana Firebaugh Ornelas

Faculty Research, Scholarly, and Creative Activity

As a key ingredient of batteries for electric vehicles (EVs), lithium plays a significant role in climate change mitigation, but lithium has considerable impacts on water and society across its life cycle. Upstream extraction methods—including open-pit mining, brine evaporation, and novel direct lithium extraction (DLE)—and downstream processes present different impacts on both the quantity and quality of water resources, leading to water depletion and contamination. Regarding upstream extraction, it is critical for a comprehensive assessment of lithium's life cycle to include cumulative impacts related not only to freshwater, but also mineralized or saline groundwater, also known as brine. Legal frameworks …


Opening The Black Box: Carbon-Footprint Calculators, Meat Consumption, And The “Wicked Problem” Of Metric Governance, E. Melanie Dupuis, Dustin Mulvaney Jan 2024

Opening The Black Box: Carbon-Footprint Calculators, Meat Consumption, And The “Wicked Problem” Of Metric Governance, E. Melanie Dupuis, Dustin Mulvaney

Faculty Research, Scholarly, and Creative Activity

Carbon-footprint calculators are widely used as communication and education tools, designed to make people aware of the ways their personal actions contribute to greenhouse-gas emissions. However, they have come under criticism for emphasizing individual behavior versus structural change. We extend this critique to argue that carbon-footprint calculators are a form of “metric governance” that not only disciplines users but also constrains their abilities to engage with the complexities of climate change and social action. We focus on a particularly wicked problem of carbon-metric governance: livestock greenhouse-gas emissions. We show that carbon-footprint calculators black box and fix the complex politics and …


Effect Of Fermentation, Malting And Ultrasonication On Sorghum, Mopane Worm And Moringa Oleifera: Improvement In Their Nutritional, Techno-Functional And Health Promoting Properties, Mpho Sebabiki Maleke, Oluwafemi Ayodeji Adebo, Jonathan Wilkin, Moira Ledbetter, Xi Feng, John Gieng, Tumisi Beiri Jeremiah Molelekoa Jan 2024

Effect Of Fermentation, Malting And Ultrasonication On Sorghum, Mopane Worm And Moringa Oleifera: Improvement In Their Nutritional, Techno-Functional And Health Promoting Properties, Mpho Sebabiki Maleke, Oluwafemi Ayodeji Adebo, Jonathan Wilkin, Moira Ledbetter, Xi Feng, John Gieng, Tumisi Beiri Jeremiah Molelekoa

Faculty Research, Scholarly, and Creative Activity

Background: Food processing offers various benefits that contribute to food nutrition, food security and convenience. This study investigated the effect of three different processes (fermentation, malting and ultrasonication) on the nutritional, techno-functional and health-promoting properties of sorghum, mopane worm and Moringa oleifera. Methods: The fermented and malted flours were prepared at 35°C for 48 h, and for ultrasonication, samples were subjected to 10 min at 4°C with amplitudes of 40–70 Hz. The biochemical, nutritional quality and techno-functional properties of the obtained flours were analysed using standard procedures. Results: Fermentation resulted in significantly lower pH and higher titratable acidity in sorghum …


Just Look At The Map: Bounding Environmental Review Of Housing Development In California, Eric Biber, Christopher S. Elmendorf, Nicholas Marantz, Moira O’Neill Jan 2024

Just Look At The Map: Bounding Environmental Review Of Housing Development In California, Eric Biber, Christopher S. Elmendorf, Nicholas Marantz, Moira O’Neill

Faculty Scholarship

California faces a dire housing crisis. California’s land-use regulatory system remains a key driver of this crisis. State law grants local governments broad power to craft their own regulations on how to review and approve housing development. Though state law may limit a locality’s ability to outright deny some types of housing development, local governments can and do use creative ways to stall approvals or functionally deny housing by making it infeasible to develop. One such strategy is to demand more intensive environmental review of new housing projects under the California Environmental Quality Act (CEQA) than what state law requires. …


Atmospheric Deposition Of Microplastics In Shiraz, Iran, Sajjad Abbasi, Farnaz Ahmadi, Nafiseh Khodabakhshloo, Haniye Pourmahmood, Atefeh Esfandiari, Zeinab Mokhtarzadeh, Shaqayeq Rahnama, Reza Dehbandi, Arya Vazirzadeh, Andrew Turner Jan 2024

Atmospheric Deposition Of Microplastics In Shiraz, Iran, Sajjad Abbasi, Farnaz Ahmadi, Nafiseh Khodabakhshloo, Haniye Pourmahmood, Atefeh Esfandiari, Zeinab Mokhtarzadeh, Shaqayeq Rahnama, Reza Dehbandi, Arya Vazirzadeh, Andrew Turner

School of Geography, Earth and Environmental Sciences

The atmosphere plays a critical role in the regional and global transportation and redistribution of microplastics (MPs). However, the significance of rainfall and its means of scavenging MPs are not well understood. In this study, MP deposition was determined during successive dry and rainy events over eight consecutive days in the Shiraz region of Iran. Flux magnitudes and temporal distributions at six sites within and outside the city (including a remote, non-urbanised location) were similar and revealed a progressive increase in MP abundance and deposition during dry periods (up to about 50 MP m−2 h−1) and subsequent relatively rapid wet …


Insights From Early Career Researcher Representatives At The Sustainability Research & Innovation Congress 2022 Asia Spotlight Event, Cho Kwong Charlie Lam Jan 2024

Insights From Early Career Researcher Representatives At The Sustainability Research & Innovation Congress 2022 Asia Spotlight Event, Cho Kwong Charlie Lam

School of Geography, Earth and Environmental Sciences

The Sustainability Research & Innovation Congress 2022 Asia Spotlight Event (SRI-ASE 2022) was held virtually from June 21-24, 2022 and co-organized by Future Earth Global Secretariat Hubs in Asia based in Japan, Taipei, China, and South Asia, during the main sessions of the SRI 2022. SRI-ASE 2022 included over 70 speakers and more than 300 participants from within and outside the Asia region. The aim of the event was to provide space to reflect on inspiring research and discussions related to the themes: New Horizons, Different Ways of Knowing, Nexus Issues, and Cross-cutting Science and Innovation in Asia. This report …


2024 Report To The Governor And Legislature On Utah's Land Water & Air, Janet Quinney Lawson Institute For Land, Water & Air Jan 2024

2024 Report To The Governor And Legislature On Utah's Land Water & Air, Janet Quinney Lawson Institute For Land, Water & Air

Reports

This report serves as a 2024 snapshot of key issues and concerns with Utah’s shared resources. It highlights a collection of data that is available to provide context to these issues and identifies areas where more study is needed. Addressing these challenges will enable Utah policymakers to make informed decisions for the future. Under the authorship of 52 researchers and with the support of 47 advisory board members, this report includes 6 chapters (Land, Water, Air, Forests and Rangelands, Bear Lake, and Metrics) that address the focus areas of the report.


Fostering Entry Level Practitioner Knowledge, Confidence, And Competence In Trauma-Informed Care Application, Mollie Keyser, Mary A. Barnes Jan 2024

Fostering Entry Level Practitioner Knowledge, Confidence, And Competence In Trauma-Informed Care Application, Mollie Keyser, Mary A. Barnes

Journal of Occupational Therapy Education

Trauma is pervasive worldwide and is associated with poor health outcomes if left unaddressed, however, a gap in practice continues to exist in the implementation of trauma-informed care (TIC). Occupational therapy practitioners will encounter individuals, communities, and populations influenced by trauma, which warrants the need for TIC to improve overall service delivery across the lifespan. However, TIC is currently not systematically integrated into any Accreditation Council for Occupational Therapy Education (ACOTE) occupational therapy educational standards. The purpose of this study was to design, implement, and evaluate a TIC application-based workshop for a sample of entry-level occupational therapy doctorate (OTD) students. …


23 Extinct Redwork Quilt Project: Repairing Relationships With Our More-Than-Human Kin, Stitch By Stich, Heather Kerley Jan 2024

23 Extinct Redwork Quilt Project: Repairing Relationships With Our More-Than-Human Kin, Stitch By Stich, Heather Kerley

Textile Society of America: Symposium Proceedings

In 2021, the United States Fish and Wildlife Service proposed 23 species for delisting from the Endangered Species Act due to extinction. I would like to present my redwork quilt, Mourning Lost Kin (23 Extinct), which honors each of these species. I plan to share my process from researching and sketching each species to the embroidering of each block and the over-all construction of the quilt. But most importantly, I would love to share the stories of these species, the layers of meaning in this quilt, and the many questions it raised for me over the course of two years. …


Three Essays On The Economics Of Sustainable Consumer Choices, Muhammad Jawad Khan Jan 2024

Three Essays On The Economics Of Sustainable Consumer Choices, Muhammad Jawad Khan

Doctoral Dissertations

This dissertation examines consumer preferences and willingness to pay (WTP) within key sustainability contexts, focusing on the remediation of forever chemicals (PFAS) in municipal water systems, forest diversification for climate-resilient maple syrup production, and reduced ecological footprints in farming. The first chapter highlights factors influencing public support for a municipal water filtration system. A contingent valuation survey was conducted in September 2021 among the New England households to estimate their WTP for PFAS filtration in municipal drinking water systems. Health factors are primary: those concerned about water quality show a higher WTP. Income, water expenditures, and filtration status at home …


Applying The Disaster Risk Assessment Framework To Sargassum Inundation In Barbados, A. Karima Degia, Micaela Small, Hazel A. Oxenford Jan 2024

Applying The Disaster Risk Assessment Framework To Sargassum Inundation In Barbados, A. Karima Degia, Micaela Small, Hazel A. Oxenford

Gulf and Caribbean Research

Episodic influxes of pelagic Sargassum into the Caribbean result in inundation of coastlines with significant negative impacts to the environment, society, and economy. The spatial complexities of this issue demand a strategy that combines spatial planning with an analytical framework that can systematically unpack the underlying factors to inform effective management. We test the application of the United Nations Disaster Risk Reduction (UNDRR) conceptual framework for disaster risk assessment to Sargassum inundation, with a focus on the hazard and exposure components of risk, using Barbados, a Caribbean Small Island Developing State (SIDS), as a case study. We first consider in …


Process Simulation For Converting Co2 Emissions From The Cementindustry To Dimethyl Ether, Nour Abou Seada, Dina Aboelela Jan 2024

Process Simulation For Converting Co2 Emissions From The Cementindustry To Dimethyl Ether, Nour Abou Seada, Dina Aboelela

Biochemical Engineering

Climate change is the leading severe problem in the twenty-first century, which is associated with greenhouse gas emissions,carbon dioxide that is the foremost cause of global warming and super greenhouse effect. In this concern, to avoid hazardousproblems, the steady stream of CO2 effluents existing in the atmosphere must be transformed to beneficial products for beingused as an abundant chemical feedstock. Implementing a new green strategy, which is known for the catalytic hydrogenationof CO2 into alternative fuels and valuable chemicals, will be a long-lasting solution to alleviate CO2 emissions. In this paper,a process simulation showing the synthesis of dimethyl ether (DME) …


Ficus Diversity And Structure Along The Ulot River Riparian Zones In Samar Island Natural Park, Maria Celeste N. Banaticla-Hilario, Anne Frances V. Buhay, Lailani A. Masungsong, Diana Shane A. Balindo, Edelyn O. Echapare, Noba F. Hilvano, Inocencio E. Buot Jr. Jan 2024

Ficus Diversity And Structure Along The Ulot River Riparian Zones In Samar Island Natural Park, Maria Celeste N. Banaticla-Hilario, Anne Frances V. Buhay, Lailani A. Masungsong, Diana Shane A. Balindo, Edelyn O. Echapare, Noba F. Hilvano, Inocencio E. Buot Jr.

Journal Article

Ficus species are keystone components of riparian ecosystems in Southeast Asia. Hence, studying their abundance and diversity in riparian areas can provide insights on the health and functions of the ecosystem. In this study, the diversity of Ficus along the riparian zone of Ulot River in Samar Island Natural Park (SINP) was evaluated by sampling across the upstream, midstream and downstream sections and using diversity indices and descriptive statistics to analyze the data. The Ulot riparian zone supports a phylogenetically diverse Ficus flora composed of 13 species representing five of the six subgenera. Three endemic species were observed namely, Ficus …


Eps 202-452: Society Techn & Environmnt, Bonchonsky Michael Jan 2024

Eps 202-452: Society Techn & Environmnt, Bonchonsky Michael

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.


Assessing The Opportunities And Risks Of Extraction In The Lithium Triangle, Jennifer Cuahutencos Jan 2024

Assessing The Opportunities And Risks Of Extraction In The Lithium Triangle, Jennifer Cuahutencos

CMC Senior Theses

Climate change mitigation efforts have grown in recent years, giving rise to energy transition technologies, including electric vehicles and grid storage, which rely heavily on lithium. The resulting acceleration of lithium demand poses an opportunity for Argentina, Bolivia, and Chile – collectively referred to as the Lithium Triangle, where more than half of the world’s lithium resources are found – to produce lithium as a way of generating revenue that can be redistributed to increase social well-being. Despite the enticing opportunity, lithium extraction has several socioecological and economic risks that may make lithium extraction a futile endeavor. This thesis aims …


Revolutionizing Lithium Extraction: Analysis Of Factors Affecting Commercialization Timelines With Insights From The Shale Gas Boom, Bilge Tayyar Jan 2024

Revolutionizing Lithium Extraction: Analysis Of Factors Affecting Commercialization Timelines With Insights From The Shale Gas Boom, Bilge Tayyar

CMC Senior Theses

This study draws parallels between Direct Lithium Extraction (DLE) and hydraulic fracturing to highlight the transformative potential of DLE technology in the lithium industry. The comparative analysis supports the hypothesis that DLE might expedite commercialization timelines, similar to the effect hydraulic fracturing has had on traditional shale gas extraction. The study includes a regression analysis to determine the factors affecting the commercialization of conventional lithium brine extraction methods, thereby better understanding the potential changes DLE will create. The regression model, based on data from 11 projects, examines the impact of variables such as temperature range, tax rates, royalty rates, regulatory …


Is Green The New Gold? Esg’S Influence On The Financial Performance Of The Energy And Mining Industries, Alexa De Vegvar Jan 2024

Is Green The New Gold? Esg’S Influence On The Financial Performance Of The Energy And Mining Industries, Alexa De Vegvar

CMC Senior Theses

The demand for Environment, Social, and Governance (ESG) reporting has increased in recent years. As the concern for climate change has moved to the forefront of the investment process, companies have needed to prioritize ESG in their operations. Previous literature addresses how ESG has benefited companies’ financial performance and increased shareholder value. The pandemic has proven to have positively impacted ESG reporting as social priorities shifted. However, studies have also shown that ESG reporting is too ambiguous to concretely display any relationship with financial performance. This thesis will analyze the impact of ESG and environmental data reporting on the Return …


Determinants And Effects Of Offset Usage Within The California Cap-And-Trade System – A Firm-Level Analysis, Adarsh Srinivasan Jan 2024

Determinants And Effects Of Offset Usage Within The California Cap-And-Trade System – A Firm-Level Analysis, Adarsh Srinivasan

CMC Senior Theses

This thesis examines the determinants of the usage of carbon offsets within the California cap-and-trade program for greenhouse gas emissions. It also investigates the relationship between a firm’s investment in offsets and its financials for publicly traded companies. Entity-level data from 2013 to 2020 was used, which was sourced from the California Air Resources Board. Multiple regression analysis was used to investigate factors that correlated with offset usage and whether offset usage correlated with EBITDA. Dummy variables indicating geographic location and economic sector of each entity were used as controls. The analysis found that total covered emissions and privately owned …


The Korean Hanok As A Model For Sustainable Architecture In South Korea, Jordan Oh Jan 2024

The Korean Hanok As A Model For Sustainable Architecture In South Korea, Jordan Oh

CMC Senior Theses

This thesis analyzes the traditional Korean hanok within the Western framework for sustainability across environmental, social, and economic dimensions. It then cross-references the findings of this analysis with existing theory on the cultural role of architecture to elucidate how the traditional Korean hanok can serve as a model for sustainable architecture in South Korea. Through a comprehensive analysis this thesis highlights the importance of architectural vernacular to define a sustainable building, and critiques contemporary Western ideas of sustainable architecture. Furthermore, this thesis synthesizes two current approaches to sustainable development in South Korea, the u-eco-city and the Green Standard for Energy …


Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 25 2024, Several Authors Jan 2024

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 25 2024, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Letter From The Faculty Editor, Beth Kegley Jan 2024

Letter From The Faculty Editor, Beth Kegley

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Featured Faculty Mentor/Student Team, Austin Jones, Ashley Dowling, Baylie Day Jan 2024

Featured Faculty Mentor/Student Team, Austin Jones, Ashley Dowling, Baylie Day

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Evaluating Efficiency And Accuracy Of Three Texture Analysis Methods For Blackberry Fruit, Rhys M. Brock, Carmen Johns, Katelyn Lust-Moore, Margaret Worthington Jan 2024

Evaluating Efficiency And Accuracy Of Three Texture Analysis Methods For Blackberry Fruit, Rhys M. Brock, Carmen Johns, Katelyn Lust-Moore, Margaret Worthington

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

A major objective of the University of Arkansas System Division of Agriculture (UADA) Fruit Breeding program is to improve the texture of blackberry (Rubus subgenus Rubus Watson). Blackberry varieties with improved fruit firmness transport and store well and may maintain superior quality under challenging postharvest conditions than softer varieties. Increased firmness may also make cultivars less susceptible to red drupelet reversion (RDR), a postharvest disorder of blackberries in which fully black drupelets revert to red after harvest. This research project aims to assess the efficiency and accuracy of three methods applied in evaluating blackberry firmness. The study compares instrumental analysis …


Understanding The Impact Of Food Insecurity Among First-Generation College Students On The University Of Arkansas Campus, Madison Price, Jennie S. Popp Ph.D., Nathan Paul Kemper, Louise Michelle Hancox Jan 2024

Understanding The Impact Of Food Insecurity Among First-Generation College Students On The University Of Arkansas Campus, Madison Price, Jennie S. Popp Ph.D., Nathan Paul Kemper, Louise Michelle Hancox

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The purpose of this study was to: 1) better understand food insecurity among first-generation college students and how it might differ from that of other college students, and 2) gather opinions from students that may serve as solutions to alleviate food insecurity. This study was conducted with a mixed-methods survey that included both open-ended and closed-ended questions. This survey had 670 responses. Nearly 10% of respondents stated that they were experiencing food insecurity. Almost 18% stated they were first-generation college students. A greater percentage of African American (P = 0.0022) and Hispanic Latino (P < 0.0001) students were first-generation compared to all other students, while a lower percentage (P < 0.0001) of Caucasian students were first-generation compared to other students. The results suggested that first-generation students were more likely to experience nine food insecurity impacts than non first-generation students. Further, both first-generation and non first-generation students indicated low levels of knowledge and/or use of existing resources on the University of Arkansas campus that can help address food insecurity needs. Finally, both first-generation and non first-generation respondents overwhelmingly favored food insecurity solutions centered around expanding access to campus food programs through lower costs and increased awareness of existing campus resources via improved advertising.


Stream Restoration Effectiveness In Mullins Creek In Fayetteville, Arkansas, Amadeo Scott, Shannon Speir Jan 2024

Stream Restoration Effectiveness In Mullins Creek In Fayetteville, Arkansas, Amadeo Scott, Shannon Speir

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Lotic waterways are vital for habitat, food, water, and flood protection, but urbanization poses a major threat to their integrity. Runoff from urban surfaces leads to pollution, flashiness, loss of biodiversity, and other symptoms, also known as Urban Stream Syndrome (USS). Streams can be restored in order to combat USS, but most restorations are not monitored, so their long-term effectiveness is unknown. This study quantitatively evaluated a decade-old stream restoration in Fayetteville, Arkansas, to assess its effectiveness in combating USS and achieving set restoration goals, and to gain insights for future restoration projects. Restoration goals included decreasing erosion and sedimentation, …


A Rare Leadership Journey: Exploring Perspectives Of Women In Construction, Taylor M. Krueger Jan 2024

A Rare Leadership Journey: Exploring Perspectives Of Women In Construction, Taylor M. Krueger

Doctor of Business Administration (DBA)

This qualitative study examined the lived experiences of female leaders in the U.S. construction industry. A narrative method and methodology was used incorporating Mezirow’s (1978) transformative learning, Super’s (1957) career development, and Cooperrider et al. 's (2008) appreciative inquiry theories. The primary research question: How do women currently leading at their respective construction firms make meaning of their leadership development experiences? Eight interpretations emerged. First, leadership development experiences occur in non-formal settings, since childhood, and rarely follow a linear path. Second, company culture or the perspective and bias of upper management strongly dictate the opportunities and occurrences of female employment, …


Climate Risk, Insurance Retreat, And State Response, Mark P. Nevitt, Michael Pappas Jan 2024

Climate Risk, Insurance Retreat, And State Response, Mark P. Nevitt, Michael Pappas

Faculty Articles

Climate change is fundamentally destabilizing the private insurance industry, with many high-profile insurance companies exiting states in the face of catastrophic, climate-­induced risk. This rapid "insurance retreat" represents a major market signal in response to climate-exacerbated risks. Private businesses are making actuarial decisions, assessing that some locations are just too vulnerable to insure. At the same time, this insurance retreat also poses a policy challenge for states as they react to the mounting insurance gaps left by exiting private insurers.

This Article analyzes insurance retreat, its attendant policy challenges, and the lessons that can be drawn from state responses. It …


Identification Of Constrained Sequence Elements Across 239 Primate Genomes, Lukas F K Kuderna, Jacob C Ulirsch, Sabrina Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J Cox, Hong Gao, Arvind Kumar, Francois Aguet, Matthew J Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Ioannis Karakikes, Kevin C Wang, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad-Toh, Jeffrey Rogers, Tomas Marques Bonet, Kyle Kai-How Farh Jan 2024

Identification Of Constrained Sequence Elements Across 239 Primate Genomes, Lukas F K Kuderna, Jacob C Ulirsch, Sabrina Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J Cox, Hong Gao, Arvind Kumar, Francois Aguet, Matthew J Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Ioannis Karakikes, Kevin C Wang, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad-Toh, Jeffrey Rogers, Tomas Marques Bonet, Kyle Kai-How Farh

Faculty, Staff and Students Publications

Noncoding DNA is central to our understanding of human gene regulation and complex diseases1,2, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome3–9. Identifying the genomic elements that have become constrained specifically in primates has been hampered by the faster evolution of noncoding DNA compared to protein-coding DNA10, the relatively short timescales separating primate species11, and the previously limited availability of whole-genome sequences12. Here we construct a whole-genome alignment of 239 species, representing nearly half of …