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Sustainability Assessment Of Photovoltaic Cells In Cross-Functional Applications, Achyuth Ravilla

Dissertations and Theses

Achieving the G7 countries' net-zero emissions target by 2050 requires integrating photovoltaic (PV) systems into diverse cross-functional applications that support sustainable energy transitions across multiple sectors. This dissertation explores the economic and environmental sustainability of three such applications: agrivoltaics, lower-dimensional materials in perovskite solar cells, and PV-electrochemical water-splitting technologies for hydrogen production. Employing life cycle assessment (LCA) and techno-economic analysis (TEA), we address the knowledge gap in comprehensive evaluations of PV-integrated solutions.

The first chapter assesses agrivoltaic systems (AVS), which combine PV systems with agriculture to mitigate land-use conflicts while enhancing food and energy production. Findings indicate that AVS designs, …

Clonal Landscape And Clinical Outcomes Of Telomere Biology Disorders: Somatic Rescue And Cancer Mutations, Fernanda Gutierrez-Rodrigues, Emma M Groarke, Natthakan Thongon, Juan Jose Rodriguez-Sevilla, Luiz Fernando B Catto, Marena R Niewisch, Ruba Shalhoub, Lisa J Mcreynolds, Diego V Clé, Bhavisha A Patel, Xiaoyang Ma, Dalton Hironaka, Flávia S Donaires, Nina Spitofsky, Barbara A Santana, Tsung-Po Lai, Lemlem Alemu, Sachiko Kajigaya, Ivana Darden, Weiyin Zhou, Paul V Browne, Subrata Paul, Justin Lack, David J Young, Courtney D Dinardo, Abraham Aviv, Feiyang Ma, Michel Michels De Oliveira, Ana Paula De Azambuja, Cynthia E Dunbar, Malgorzata Olszewska, Emmanuel Olivier, Eirini P Papapetrou, Neelam Giri, Blanche P Alter, Carmem Bonfim, Colin O Wu, Guillermo Garcia-Manero, Sharon A Savage, Neal S Young, Simona Colla, Rodrigo T Calado

Faculty, Staff and Student Publications

Telomere biology disorders (TBDs), caused by pathogenic germ line variants in telomere-related genes, present with multiorgan disease and a predisposition to cancer. Clonal hematopoiesis (CH) as a marker of cancer development and survival in TBDs is poorly understood. Here, we characterized the clonal landscape of a large cohort of 207 patients with TBD with a broad range of age and phenotype. CH occurred predominantly in symptomatic patients and in signature genes typically associated with cancers: PPM1D, POT1, TERT promoter (TERTp), U2AF1S34, and/or TP53. Chromosome 1q gain (Chr1q+) was the commonest karyotypic abnormality. Clinically, multiorgan involvement and CH in TERTp, TP53, …

Who Is Most At Risk?: Identifying The Risks For Mental Health Problems Related To Social Media, Jessica L. Hamilton, Kaylee P. Kruzan, Hannah Szlyk, Jazmin Reyes-Portillo, Candice Biernesser, Michaeline Jensen, Jamie Zelazny, Brian Primack, John Torous

Department of Psychology Faculty Scholarship and Creative Works

Although most adolescents use social media, not all experience negative effects on their mental health. Identifying which youths are most vulnerable to mental health problems related to social media remains a critical area of research to inform prevention. Currently, there is insufficient examination of the potential moderators of the relationship between social media use and mental health outcomes, limiting our understanding. Research has primarily focused on which youths are most at risk on the basis of demographic factors and preexisting mental health problems. Findings suggest that cisgender girls, youths with minoritized identities, and those from lower socioeconomic backgrounds or with …

Spectator 2024-12-05, Editors Of The Spectator

The Spectator

No abstract provided.

Amniotic Fluid-Derived Stem Cells: Potential Factories Of Natural And Mimetic Strategies For Congenital Malformations, Cristiane S R Fonteles, Julia Enterria-Rosales, Ying Lin, John W Steele, Ramiro A Villarreal-Leal, Jing Xiao, Daniel I Idowu, Beck Burgelin, Bogdan J Wlodarczyk, Richard H Finnell, Bruna Corradetti

Faculty, Staff and Students Publications

BACKGROUND: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedures. Here, we present naturally occurring exosomes (EXOs) isolated from amniotic fluid-derived MSCs (AF-MSCs) and their mimetic analogs (MIMs) as viable, reproducible, and stable alternatives. These nanovesicles present a minimally invasive therapeutic option, addressing the limitations of MSC-based treatments while retaining therapeutic efficacy.

METHODS: MIMs were generated from AF-MSCs by combining sequential filtration steps through filter membranes with different porosity and size exclusion …

3d Genome Topology Distinguishes Molecular Subgroups Of Medulloblastoma, John J Y Lee, Michael J Johnston, Hamza Farooq, Huey-Miin Chen, Subhi Talal Younes, Raul Suarez, Melissa Zwaig, Nikoleta Juretic, William A Weiss, Jiannis Ragoussis, Nada Jabado, Michael D Taylor, Marco Gallo

Faculty, Staff and Students Publications

Four main medulloblastoma (MB) molecular subtypes have been identified based on transcriptional, DNA methylation, and genetic profiles. However, it is currently not known whether 3D genome architecture differs between MB subtypes. To address this question, we performed in situ Hi-C to reconstruct the 3D genome architecture of MB subtypes. In total, we generated Hi-C and matching transcriptome data for 28 surgical specimens and Hi-C data for one patient-derived xenograft. The average resolution of the Hi-C maps was 6,833 bp. Using these data, we found that insulation scores of topologically associating domains (TADs) were effective at distinguishing MB molecular subgroups. TAD …

Exploration Of The Tunability Of Brd4 Degradation By Dcaf16 Trans-Labelling Covalent Glues, Muhammad Murtaza Hassan, Yen-Der Li, Michelle W Ma, Mingxing Teng, Woong Sub Byun, Kedar Puvar, Ryan Lumpkin, Brittany Sandoval, Justine C Rutter, Cyrus Y Jin, Michelle Y Wang, Shawn Xu, Anna M Schmoker, Hakyung Cheong, Brian J Groendyke, Jun Qi, Eric S Fischer, Benjamin L Ebert, Nathanael S Gray

Faculty, Staff and Students Publications

Chemically induced proximity modalities such as targeted protein degradation (TPD) hold promise for expanding the number of proteins that can be manipulated pharmacologically. However, current TPD strategies are often limited to proteins with preexisting ligands. Molecular glues (e.g. glutarimide ligands for CUL4CRBN), offer the potential to target undruggable proteins. Yet, their rational design is largely unattainable due to the unpredictability of the ‘gain-of-function’ nature of the glue interaction upon chemical modification of ligands. We recently reported a covalent trans-labelling glue mechanism which we named ‘Template-assisted covalent modification’, where an electrophile decorated BRD4 inhibitor was effectively delivered to …

Rna Splicing As A Biomarker And Phenotypic Driver Of Meningioma Dna-Methylation Groups, Nathan K Leclair, Abrar Choudury, William C Chen, Stephen T Magill, Kathleen Mccortney, Craig M Horbinski, Zhenhong Chen, Ezequiel Goldschmidt, Charlotte D Eaton, Ketan R Bulsara, Wenya Linda Bi, Akash J Patel, Felix Sahm, David Raleigh, Olga Anczukow

Faculty, Staff and Students Publications

BACKGROUND: Advances in our understanding of the molecular biology of meningiomas have led to significant gains in the ability to predict patient prognosis and tumor recurrence and to identify novel targets for therapeutic design. Specifically, classification of meningiomas based on DNA methylation has greatly improved our ability to risk stratify patients, however new questions have arisen in terms of the underlying impact these DNA-methylation signatures have on meningioma biology.

METHODS: This study utilizes RNA-sequencing data from 486 meningioma samples corresponding to 3 meningioma DNA-methylation groups (merlin-intact, immune-enriched, and hypermitotic), followed by in vitro experiments utilizing human meningioma cell lines.

RESULTS: …

Integrating Drug Target Information In Deep Learning Models To Predict The Risk Of Adverse Events In Patients With Comorbid Post-Traumatic Stress Disorder And Alcohol Use Disorder, Oshin Miranda, Xiguang Qi, M Daniel Brannock, Ryan Whitworth, Thomas R Kosten, Neal David Ryan, Gretchen L Haas, Levent Kirisci, Lirong Wang

Faculty, Staff and Students Publications

Background/Objectives: Comorbid post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) patients are at a significantly higher risk of adverse outcomes, including opioid use disorder, depression, suicidal behaviors, and death, yet limited treatment options exist for this population. This study aimed to build on previous research by incorporating drug target information into a novel deep learning model, T-DeepBiomarker, to predict adverse outcomes and identify potential therapeutic medications.

Methods: We utilized electronic medical record (EMR) data from the University of Pittsburgh Medical Center (UPMC), analyzing 5565 PTSD + AUD patients. T-DeepBiomarker was developed by integrating multimodal data, including lab results, drug …

25 Not Out: A Tale Of Two Cities, Vijayendra Pratap Singh Mr., Abhisar Vidyarthi Mr.

National Law School Business Law Review

The enactment of the principal arbitration legislation in India, the Arbitration & Conciliation Act, 1996, notably coincided with the enactment of the United Kingdom’s Arbitration Act, 1996. While both turned 25 years old in 2021, the two jurisdictions have seen distinct paths in the development and evolution of their respective arbitration landscapes. London, traditionally, has always been a significant seat of arbitration for parties around the world due to its consistent pro-arbitration outlook. India, on the other hand, had a questionable decade following the enactment of the Indian Arbitration Act, but is now gradually moving towards establishing itself as a …

Mutation Of The Trademark Doctrine: Analysing Actionable Use To Reconcile Brand Identities With Constitutional Safeguards, M.P. Ram Mohan Mr., Aditya Gupta Mr.

National Law School Business Law Review

With continuous and consistent use, trademarks can come to signify opulence, luxury, and dependability; and become cultural icons. The modern trademark doctrine must accommodate these realities of the marketplace while, at the same time, accommodating the flourishing exchange of expressive uses through unauthorised use of trademarks. This push-and-pull has resulted in the complete obliteration of what were already obscure boundaries between the expressive and marketing spheres of trademark law. The present study examines the normative foundations of the modern trademark doctrine, drawing from American, English, and European trademark jurisprudence. These foundations are then extrapolated to Indian trademark law to create …

Bounded By Place: Rural Students, College Knowledge, Educational Motivation, And College Going, Sarah Rutt Williams, Frimpomaa Ampaw, Skylar R. Duke, Anne M. Hornak

Mid-Western Educational Researcher

Rural students face inequitable access to educational opportunities when compared to their suburban and urban counterparts (Koricich et al., 2018; Ovink et al., 2018), and their postsecondary experiences and outcomes remain understudied. Research on the role of college knowledge in the persistence of this educational inequity is particularly scarce. Using a non-experimental survey design, the present study seeks to understand the effect of rural students’ college knowledge on their postsecondary intentions. We use surveys completed by rural high school seniors and logistic regression to analyze the relationship between students’ college knowledge, their motivation, and their postsecondary plans. Our findings show …

A Comparative Study Of Yoga And Stoicism For Achieving Mental Well-Being, Dr. R K Roshni Raj Lakshmi, Mr. Puyam Robinchandra Singh

Journal of Applied Yoga Studies

Background: The ideal way of life is a question perused upon by many thinkers. Western philosophy as well as Indian philosophy has dwelled on this. A common thread can be seen running through philosophical schools of stoicism and yoga. Evidence can be seen in both schools of philosophy to prove this similarity. The concepts of stoicism like the dual powers leading to creation, concept of eudemonia, restraint of sense organs and control of desire find their equivalent concepts in yoga texts. It can be thus, concluded that stoicism can be seen intertwined in yoga philosophy.

Aim of the philosophical study: …

Introduction To Geomorphology By Frank Ahnert., Caroline Davis

The Geographical Bulletin

This English translation of Ahnert's Einfuhrung in die Geomorph%gie is not the standard descriptive catalog of geomorphic form and landscapes. It provides an introductory textbook which is strongly grounded in systems theory and process-oriented geomorphology. This text provides more than a short general reference to theory. The theoretical foundations of geomorphology are clearly presented and accessible at the introductory level. To have process response models emphasized in an introductory text is unusual and refreshing. In addition, the theoretical themes are linked throughout the text to processes and descriptions.

A Geography Of Ohio By Leonard Peacefull, Thomas A. Rumney

The Geographical Bulletin

Leonard Peacefull's new volume on the geography of Ohio arrives on the scene during a period of renewed and ex - panded interest in regional geography at all scales. What follows here is an ac - counting ofthis new and useful text on an important state of the United States. After a brief introduction, a team of au - thors cover in sixteen chapters the fun - damental components, patterns, and pro - cesses of Ohio's geographic character. The first four discuss the environments and mineral resources of Ohio (Peacefull, Schmiolin, Nash and Gerber, and Peacefull, respectively). Noting that Ohio's …

The Context Of Mahan's 'Debatable Zone', William D. Walters, Jr.

The Geographical Bulletin

At the turn of the 19th century American naval historian Alfred Thayer Mahan (1840- 1914) developed a concept which he called the "Debatable Zone". This was a wide arc stretching from Turkey to China which Mahan argued was the key to future world development. Mahan's Debatable Zone has become the best known American contribution to early geopolitical thinking, and is often seen as one of the roots of Mackinder's heartland theory. However, Mahan's ideas can be better understood in the context of popular writing on Asia at the time. Although he had the ear of key American political figures, they …

Timss 2023 Australia: Highlights On Australian Student Performance, Nicole Wernert, Marina Schmid, Sima Rodrigues

TIMSS 2023

Australia participated in the eighth cycle of the Trends in International Mathematics and Science Study (TIMSS). TIMSS is an international sample study that assesses the mathematics and science achievement of Year 4 and Year 8 students every 4 years. Australia has participated in all cycles of TIMSS since it commenced in 1995 and over this 28-year period has collected rich data about trends in mathematics and science achievement. TIMSS 2023 expanded its scope to assess environmental knowledge and attitudes. This new component provides valuable insights into students’ understanding of environmental issues, including climate change, biodiversity, and conservation. This Highlights report …

Timss 2023 Australia. Volume 1: Student Performance, Nicole Wernert, Marina Schmid, Sima Rodrigues

TIMSS 2023

The Trends in International Mathematics and Science Study (TIMSS) is an international comparative study of student achievement directed by the International Association for the Evaluation of Educational Achievement (IEA). TIMSS was first conducted in 1995 and the 2023 assessment formed the eighth cycle, providing 28 years of trends in mathematics and science achievement at Year 4 and Year 8. In Australia, TIMSS is managed by the Australian Council for Educational Research (ACER) and is jointly funded by the Australian Government and the state and territory governments. TIMSS is a key part of Australia’s National Assessment Program. The goal of TIMSS …

Cascon 2024, College Of Arts And Sciences

SHU Faculty Publications

No abstract provided.

Minutes 12-4-2024 | Institutional Effectiveness, Writing Across The Curriculum Subcommittee, Katelyn Walker

Institutional Effectiveness Committee Minutes

No abstract provided.

Shame, Loneliness, Regret: Analyzing Theeffectiveness Of Anti-Alcohol Marketing Campaigns On Consumers, Zakary Bradbury

Honors Projects in Marketing

The alcohol market has been growing exponentially worldwide over the past decade with no trends of stopping in the near future. With this growth comes an increase in marketing efforts from both pro-alcohol companies and anti-alcohol agencies. While pro-alcohol companies have not had any trouble regarding marketing, anti-alcohol agencies have lagged behind in terms of social and digital marketing efforts. The goal of this research was to uncover how various anti-alcohol stimuli affect consumer attitudes and beliefs. To conduct research, we ran a Qualtrics survey consisting of 279 college students. The results showed that 1) when participants viewed an anti-alcohol …

Constitutional Absolutism? Feudal Kingship In Late Restoration Royalism, 1679-1688, Jacob Rundle

Honors Program Theses and Projects

No abstract provided.

December 4, 2024 (Vol. 109, No. 14), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.

Wood, Robert Chapman, San Jose State University

Emeritus and Retired Faculty Biographies

Harvard Business School, Post-Doctoral Research Fellow, 2000-2001

Boston University, School of Management, DBA 2000

Williams College, BA 1971

Police Officer Perceptions Of Mental Wellbeing Needs: A Multi-Methods Study, Suzanne Hakeos

MUSC Theses and Dissertations

Police officers are exposed to repeated traumatic exposures (e.g., deaths, abuse, threats to personal and community member safety) and organizational stressors (e.g., poor leadership and support, low job control) throughout their careers. These job-related exposures and stressors have been shown to increase the officers’ risk for developing physical (e.g., cardiovascular disease, sleep deprivation) and mental health issues (e.g., depression, anxiety, hypervigilance, post-traumatic stress disorder, hopelessness, substance abuse, self-isolation, suicidal ideations). Outside of their work environment and duties, factors and stressors related to the officer (e.g., beliefs, values, coping strategies, personality, life experiences), interpersonal relationship dynamics (e.g., work-family demands, conflict, support), …

A Frame, A Jar, And A Mural: An Exploratory Crafts-Based Arts Curriculum Infused With Making, Community, And Place, Laura Ann Rowley

Theses and Dissertations

Situated within the current landscape of loneliness and isolation facing today's youth, this research describes a place-based and crafts-based arts curriculum for elementary students in the Salt Lake area. It uses curriculum as an investigative tool to explore the relationships between crafts, place, making, community and belonging. The curriculum itself incorporates place-based activities including hikes, urban walks, and plein air making while looking at the lives and works of local Salt Lake maker-artists Pilar Pobil, Jann Haworth, and Ben Behunin. It also delves into a wide array of craft arts and making including: decorative frame painting, embroidery, quilting, pottery, rubbings, …

Propagation Modeling Of Terahertz Reflections And Reflector Design For Mimo Channel, Thanh Ngoc Dan Le

Dissertations and Theses

Wireless communication has transformed connectivity, enabling seamless access across devices without physical constraints. Terahertz (THz) frequencies, ranging from 100 GHz to 10 THz, promise high-bandwidth channels crucial for applications like IoT and virtual reality. However, deploying THz communication faces challenges due to significant propagation limitations such as high attenuation and environmental absorption. The motivation behind this research is to develop a comprehensive understanding of THz propagation dynamics and utilize reflective surfaces to create multipath environments for an improvement in the capacity performance of MIMO channels.

This research investigates the potential of Multi-Input Multi-Output (MIMO) channels at THz frequencies to overcome …

Recontextualized Knowledge: Available Designs Of The Long-Form Youtube Video Essay, Michelle Lynn Arendt

Dissertations and Theses

Recontextualization - the intricate process of transferring meaning material from one social semiotic context to another - is the primary avenue through which science and social science are communicated to general audiences. The prevailing popularity of social media platforms such as YouTube has encouraged a digital turn in recontextualization research and practice, with considerable emphasis given to navigating web 2.0's unique participation structure. However, compared to professional organizations, which contribute the largest amount of recontextualized scientific or social scientific content to social media platforms, independent user-generated creators consistently produce more successful content. Of interest to this project is the YouTube …

Applying Positive Unlabeled Learning Techniques And Using The Kullback-Leibler Divergence To Improve Geothermal Surveying Assessments, Martín Thomas Rodriguez

Dissertations and Theses

As we face the current climate crisis, the discovery of geothermal energy resources has the potential to greatly reduce our dependence on fossil fuels worldwide. However, the development of any new energy infrastructure is expensive and depends on the willingness of energy agencies and developers to make initial investments based on calculated risk measures. One such measure, called geothermal favorability, is the likelihood that a site has conditions favorable for geothermal systems containing recoverable energy potential. Its prediction from existing geophysical datasets proves to be a nontrivial task. The prediction of geothermal favorability can be framed as a binary classification …

The Routledge International Handbook Of Engineering Ethics Education, Shannon Chance, Tom Børsen, Diana Adela Martin, Roland Tormey, Thomas Taro Lennerfors, Gunter Bombaerts

Research Outputs: 2025-Present

Responding to the need for a timely and authoritative volume dedicated to this burgeoning and expansive area of research, this handbook will provide readers with a map of themes, topics, and arguments in the field of engineering ethics education (EEE). Featuring critical discussion, research collaboration, and a team of international contributors of globally recognized standing, this volume comprises six key sections which elaborate on the foundations of EEE, teaching methods, accreditation and assessment, and interdisciplinary contributions. Over 100 researchers of EEE from around the globe consider the field from the perspectives of teaching, research, philosophy, and administration. The chapters cover …