Digital Commons Network^™

An Autoethnographic Dialogue With Motherhood Literature, Maya Autret, Brad Van Eeden-Moorefield

The Qualitative Report

This autoethnography represents the first author’s journey as a mother and doctoral student researching mothers’ experiences in contending with the demands of work and family. Reading across different pockets of empirical motherhood literature (work-family conflict, contemporary motherhood, maternal gatekeeping, and intensive motherhood) I became troubled by how women’s realities were reflected. Pushing back against traditional methods that endorse separating my researcher identity from my maternal self, I draw on autoethnographic method to dialogue with this literature. This approach empowers me to speak out as a novice scholar uncomfortable with aspects of literature, while also navigating training in the use of …

Mutiny For A Bounty, Emily Strauss, Joseph A. Grundfest

Faculty Scholarship

Experience teaches that attorneys may violate duties of confidentiality and trust to pursue personal gain. Multiple insider trading, embezzlement, and fraud prosecutions prove the point. The Dodd-Frank Act of 2010 establishes a bounty regime whereby certain whistleblowers are eligible for awards of 10%–30% of Securities and Exchange Commission (“SEC”) enforcement recoveries exceeding $1 million. Since its inception, this program has paid at least 207 whistleblowers more than $1 billion. The Commission’s bounty program thus may be a meaningful inducement to breach privilege.

The SEC asserts that its whistleblower authority preempts state law and that it can accept attorney–client privileged information. …

Ai And Antitrust: "The Algorithm Made Me Do It", Robin C. Feldman, Caroline A. Yuen

Faculty Scholarship

As the dawn of artificial intelligence (“AI”) rises rapidly, competition authorities should contemplate the potential for hazy days ahead. Undoubtedly, AI’s already ubiquitous presence offers exciting possibilities, from enhancing efficiency, to leveling the playing field for non-native speakers, to enabling scientific discovery. Despite these breathtaking advancements, however, recent data from the Pew Research Center reveal that only 15% of adults surveyed were “more excited than concerned about the increasing use of AI in daily life,” with 46% expressing “an equal mix of concern and excitement.”

Policymakers also manifest concerns about AI, exemplified by the extent to which government actors are …

Selective Fast Fiber Damage After Leg Press Exercise Leading To Failure: A Pole Vaulter Case Report, Gerard Carmona, Gerard Moras, Raúl Bescós, Adrián García-Fresneda, Joan A. Cadefau

School of Health Professions

The aim of this study was to investigate, in a trained pole vaulter (PV) and in an endurance-trained physical education student (PE), the effect of a leg press exercise leading to failure (LPF) on changes in serum activity of muscle enzymes and serum concentration of fast (FM) and slow (SM) myosin isoforms, while simultaneously examining mechanical output components as indicators of performance and fatigue developed throughout exercise. A case report study design based on an observational comparison of response between two dichotomous participants, PV and PE, was used. Differences between the participants’ exercise outputs were examined by unpaired t-test or …

Drug-Resistant Epilepsy And Ketogenic Diet Therapy – A Qualitative Study Of Families’ Experiences, Jennifer H. Carroll, Tracey Parkin, J. Helen Cross, Mary Hickson, Emma Williams, Val Aldridge, Avril Collinson

School of Health Professions

Background: A diagnosis of drug-resistant epilepsy is life changing for a family. Ketogenic diet therapy (KDT) can offer hope when other treatments have failed. However, it often requires a significant change in daily routine and dietary habits. This qualitative descriptive study aimed to explore families’ experiences of epilepsy and KDT. Methods: Parents of a child aged ≤18 years with epilepsy, currently or recently treated with KDT, were recruited from the UK and internationally via UK Ketogenic Diet (KD) centres, charities, and social media. Semi-structured interviews were audio recorded, transcribed verbatim, anonymised, coded using Nvivo (V12), and inductive thematic analysis undertaken. …

Specialist Physiotherapy For Functional Motor Disorder In England And Scotland (Physio4fmd): A Pragmatic, Multicentre, Phase 3 Randomised Controlled Trial, Physio4fmd Study Group, Glenn Nielsen, Jon Stone, Teresa C. Lee, Laura H. Goldstein, Louise Marston, Rachael Maree Hunter, Alan Carson, Kate Holt, Jon Marsden, Marie Le Novere, Irwin Nazareth, Hayley Noble, Markus Reuber, Ann Marie Strudwick, Beatriz Santana Suarez, Mark J. Edwards, Emily Beaves, David Breen, Christine Burness, Simone Caddy, Hannah Callaghan, Andrew Carberry, Luke Chetham, Andrea Clyne, Susie Cobb, Jan Coebergh, Lewis Cook, Patrick Cookson

School of Health Professions

Background: Functional motor disorder—the motor variant of functional neurological disorder—is a disabling condition that is commonly associated with poor health outcomes. Pathophysiological models have inspired new treatment approaches such as specialist physiotherapy, although evidence from large randomised controlled trials is absent. We aimed to assess the clinical effectiveness of a specialist physiotherapy intervention for functional motor disorder compared with treatment as usual. Methods: In this pragmatic, multicentre, phase 3 randomised controlled trial at 11 hospitals in England and Scotland, adults with a clinically definite diagnosis of functional motor disorder, diagnosed by a neurologist, were included. Participants were randomly assigned (1:1, …

Multi-Ancestry Genome-Wide Association Meta-Analysis Of Parkinson’S Disease, Jonggeol Jeffrey Kim, Dan Vitale, Diego Véliz Otani, Michelle Mulan Lian, Karl Heilbron, Stella Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Katarzyna Bryc, Emily Bullis, Paul Cannon, Daniella Coker, Gabriel Cuellar Partida, Devika Dhamija, Sayantan Das, Sarah L. Elson, Nicholas Eriksson, Teresa Filshtein, Alison Fitch, Kipper Fletez-Brant, Pierre Fontanillas, Will Freyman, Julie M. Granka, Alejandro Hernandez, Barry Hicks, David A. Hinds, Ethan M. Jewett, Yunxuan Jiang

Peninsula Medical School

Although over 90 independent risk variants have been identified for Parkinson’s disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson’s disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African ancestry. In a meta-analysis, we identified 78 independent genome-wide significant loci, including 12 potentially novel loci (MTF2, PIK3CA, ADD1, SYBU, IRS2, USP8, PIGL, FASN, MYLK2, USP25, EP300 and PPP6R2) and fine-mapped 6 putative causal variants at 6 known PD loci. By combining our …

Insights From Early Career Researcher Representatives At The Sustainability Research & Innovation Congress 2022 Asia Spotlight Event, Cho Kwong Charlie Lam

School of Geography, Earth and Environmental Sciences

The Sustainability Research & Innovation Congress 2022 Asia Spotlight Event (SRI-ASE 2022) was held virtually from June 21-24, 2022 and co-organized by Future Earth Global Secretariat Hubs in Asia based in Japan, Taipei, China, and South Asia, during the main sessions of the SRI 2022. SRI-ASE 2022 included over 70 speakers and more than 300 participants from within and outside the Asia region. The aim of the event was to provide space to reflect on inspiring research and discussions related to the themes: New Horizons, Different Ways of Knowing, Nexus Issues, and Cross-cutting Science and Innovation in Asia. This report …

Contrasting Species-Specific Stress Response To Environmental Ph Determines The Fate Of Coccolithophores In Future Oceans, Nishant Chauhan, Craig J. Dedman, Chloë Baldreki, Adam A. Dowle, Tony R. Larson, Rosalind E.M. Rickaby

School of Geography, Earth and Environmental Sciences

Molecular mechanisms driving species-specific environmental sensitivity in coccolithophores are unclear but crucial in understanding species selection and adaptation to environmental change. This study examined proteomic and physiological changes in three species under varying pH conditions. We showed that changing pH drives intracellular oxidative stress and changes membrane potential. Upregulation in antioxidant, DNA repair and cell cycle-related protein-groups indicated oxidative damage across high (pH 8.8) and low pH (pH 7.6) compared to control pH (pH 8.2), and correlated with reduced growth rates. Upregulation of mitochondrial proteins suggested higher metabolite demand for restoring cellular homeostasis under pH-induced stress. Photosynthetic rates generally correlated …

Drone Imagery And Deep Learning For Mapping The Density Of Wild Pacific Oysters To Manage Their Expansion Into Protected Areas, Aser Mata, David Moffat, Sílvia Almeida, Marko Radeta, William Jay, Nigel Mortimer, Katie Awty-Carroll, Oliver Thomas, Vanda Brotas, Steve Groom

School of Geography, Earth and Environmental Sciences

The recent expansion of wild Pacific oysters already had negative repercussions on sites in Europe and has raised further concerns over their potential harmful impact on the balance of biomes within protected areas. Monitoring their colonisation, especially at early stages, has become an urgent ecological issue. Current efforts to monitor wild Pacific oysters rely on “walk-over” surveys that are highly laborious and often limited to specific areas of easy access. Remotely Piloted Aircraft Systems (RPAS), commonly known as drones, can provide an effective tool for surveying complex terrains and detect Pacific oysters. This study provides a novel workflow for automated …

Empirically Assessing Medical Device Innovation, George Horvath

Faculty Scholarship

No abstract provided.

Dance Of The Biologics, Robin Feldman, Gideon Schor

Faculty Scholarship

From COVID-19 vaccines to cancer treatments, biologic medicines are gaining importance in the U.S. health care system. Their high price tags, however, make these medications difficult for many Americans to afford. The Biosimilars Act, enacted in 2010, aimed to reduce costs and increase access to biologic medications by encouraging follow-on competition. The legislative effort followed in the footsteps of its predecessor, the Hatch-Waxman Act of 1984.

Although the Hatch-Waxman system succeeded in creating a landscape of more affordable and widely used generic drugs, the Biosimilars Act has failed to live up to its promise. Biologic drugs in the United States …

Ai & Antitrust: The Algorithm Made Me Do It, Robin Feldman, Caroline Yuen

Faculty Scholarship

As the dawn of artificial intelligence (“AI”) rises rapidly, competition authorities should contemplate the potential for hazy days ahead. Undoubtedly, AI’s already ubiquitous presence offers exciting possibilities, from enhancing efficiency, to leveling the playing field for non-native speakers,to enabling scientific discovery.Despite these breathtaking advancements, however, recent data from the Pew Research Center reveal that only 15% of adults surveyed were “more excited than concerned about the increasing use of AI in daily life,” with 46% expressing “an equal mix of concern and excitement.”

Policymakers also manifest concerns about AI, exemplified by the extent to which government actors are racing to …

Hierarchies Of Discrimination In Baby Making? A Response To Professor Carroll, Radhika Rao

Faculty Scholarship

No abstract provided.

Toward A Taxonomy Of Freedom Of Movement Claims: Identifying Rights-Based Pathways For Today’S Refugees Beyond The 1951 Refugee Convention, Moria Paz

Faculty Scholarship

This Article discusses the current migratory crisis as one instance of a conceptual mismatch in human rights between formal law and the tools that courts and other quasi-judicial bodies actually utilize in adjudication. While the doctrine centers around individual right-holders, enforcement bodies provide a remedy only when there is a state duty-holder. Human rights scholarship regarding refugees focuses on the right to freedom of movement. However, this right frequently offers little benefit to these individuals adrift at sea or wandering in the desert.

An alternative framing might ultimately be more effective before human rights courts and other quasi-judicial bodies. This …

Effect Of Alkaline Water In Controlling Oral Ph, Duc M. Nguyen

Dental Hygiene ETDs

This study was motivated by the widespread prevalence of dental caries, acknowledged as a global concern and often deemed a pandemic, coupled with the realization of limitations in existing caries prevention methods. The surge in the popularity of alkaline water for daily use, recognized for its health benefits, prompted an exploration of its potential role in averting dental caries. The central hypothesis, focusing on the remineralization benefits of alkaline water as a preventive method for dental caries, formed the basis of investigation. Structured with two phases and five steps, the study aimed to evaluate the impact of alkaline water on …

Cheating And The Effect Of Promises In Indian And German Children, Patricia Kanngiesser, Jahnavi Sunderarajan, Jan K. Woike

School of Psychology

Cheating is harmful to others and society at large. Promises have been shown to increase honesty in children, but their effectiveness has not been compared between different cultural contexts. In a study (2019) with 7- to 12-year-olds (N = 406, 48% female, middle-class), voluntary promises reduced cheating in Indian, but not in German children. Children in both contexts cheated, but cheating rates were lower in Germany than in India. In both contexts, cheating decreased with age in the (no-promise) control condition and was unaffected by age in the promise condition. These findings suggest that there may exist a threshold beyond …

The Importance Of Acoustic Output Measurement And Monitoring For The Replicability Of Transcranial Ultrasonic Stimulation Studies, Miriam C. Klein-Flügge, Elsa F. Fouragnan, Eleanor Martin

School of Psychology

No abstract provided.

Reward Count(S): Negative Recency In Probabilistic Experience-Based Learning, Andy Wills, René Schlegelmilch, Bettina Von Helversen

School of Psychology

Learning how to make decisions from experience is often studied using probabilistic outcome prediction or choice tasks, asin conditioning, reward learning, or risky gambles (e.g., response A provides reward in 75% of the cases, response B in25% over repeated trials with feedback). One debated phenomenon in such tasks is that of negative recency, describingthat learners expect the rare event after observing a streak ofcommon events (e.g., Gamblers fallacy). Here, we show thatthis behavior, despite instructing participants to use a visualstimulus, also occurs in probabilistic single-cue conditioningtraining, where participants predicted whether digging at a specific location on a plane (visual cue) …

Psychosocial Factors Associated With Physical Activity In People With Dementia: A Pilot Cross-Sectional Study, Nicolas Farina, Uzma Niazi, Riona Mc Ardle, Johanna Eronen, Ruth Lowry, Sube Banerjee

Peninsula Medical School

Objectives: To understand how psychosocial factors associated with physical activity differ based on disease severity in people with dementia, and how these factors are associated with physical activity participation. Methods: Eighty-seven people with dementia, alongside their family carer were asked to complete a series of questions related to physical activity participation, including barriers, motivators, and facilitators. Regression models were developed to understand how psychosocial factors were associated with physical activity participation in the cohort. Results: In the final models, only the absence of intrapersonal barriers was associated with overall physical activity and regular moderate-to-vigorous physical activity. Feelings of relatedness were …

Support Vector Regression To Predict Power Consumption, Alireza Ghasempour

Electrical & Computer Engineering Technical Reports

No abstract provided.