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2024

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Bacillus Thuringiensis Cry14a Family Proteins As Novel Anthelmintics Against Gastrointestinal Nematode Parasites, Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R. Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A. Darfour, Elizabeth Kass, Katherine H. Petersson, Martin Krarup Nielsen, Heiko Liesegang, Gary R. Ostroff, Raffi V. Aroian Oct 2024

Bacillus Thuringiensis Cry14a Family Proteins As Novel Anthelmintics Against Gastrointestinal Nematode Parasites, Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R. Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A. Darfour, Elizabeth Kass, Katherine H. Petersson, Martin Krarup Nielsen, Heiko Liesegang, Gary R. Ostroff, Raffi V. Aroian

Veterinary Science Faculty Publications

Bacillus thuringiensis crystal (Cry) proteins have been expressed in commercial transgenic crops for nearly 30 years, providing safe and effective control of insect pests and significantly reducing the application of hazardous chemical pesticides. B. thuringiensis crystal proteins have also been shown to target parasitic nematodes, including plant parasitic nematodes. Recently, transgenic soybean crops expressing Cry14Ab have been shown to provide control against the soybean cyst nematode Heterodera glycines, marking the first time a crystal protein is being commercialized in transgenic crops for control of a nematode pest. However, apart from H. glycines and the free-living nematode, Caenorhabditis elegans, the breadth …


Arthropod Arbiters: Natural Enemy Communities Mediate The Effects Of Landscape And Local-Scale Complexity On Lygus-Induced Crop Loss In Organic Strawberries, Adrian Lu, David J. Gonthier, Amber Sciligo, Karina Garcia, Taiki Chiba, Gila Juárez, Claire Kremen Oct 2024

Arthropod Arbiters: Natural Enemy Communities Mediate The Effects Of Landscape And Local-Scale Complexity On Lygus-Induced Crop Loss In Organic Strawberries, Adrian Lu, David J. Gonthier, Amber Sciligo, Karina Garcia, Taiki Chiba, Gila Juárez, Claire Kremen

Entomology Faculty Publications

Sustainable pest management requires growers and regional land managers to consider the relationships among pest management practices, pest and natural enemy communities, crop loss, and multi-scalar habitat complexity. However, the causal links among these variables, in particular potential interactions between landscape and local-scale habitat complexity, remain underexplored. In the context of organically managed strawberry crops in California’s Central Coast, we tested the independent effects of landscape and local habitat complexity gradients on arthropod communities and crop loss using a piecewise structural equation model (PSEM). We found that landscape-scale woody habitat proportion indirectly decreased crop loss through its positive effect on …


Saraqib Thobe Identification In The May Weber Ethnographic Collection, Gretchen Rojewski Oct 2024

Saraqib Thobe Identification In The May Weber Ethnographic Collection, Gretchen Rojewski

Department of Anthropology

The artistic tradition of embroidery in communities across the Arabian Peninsula has long served as a means of expressing local identity, values, and craftsmanship through the decoration of garments. Distinctive patterns, stylistic choices, and color palettes allow for the regional identification of embroidered clothing. This research examines a Syrian thobe housed in the May Weber Ethnographic Collection at Loyola University Chicago, using physical analysis and comparative study to identify its origins. By analyzing the garment’s embroidery patterns, construction techniques, and aesthetic details, this study not only determines the likely regional provenance of the thobe but also explores the broader cultural …


Triumphant Philanthropists: Inventing An American Tradition In Milwaukee, Wisconsin, And The Nation, 1844-1930, Margaret Nettesheim-Hoffmann Oct 2024

Triumphant Philanthropists: Inventing An American Tradition In Milwaukee, Wisconsin, And The Nation, 1844-1930, Margaret Nettesheim-Hoffmann

Dissertations (1934 -)

This dissertation explores the development of American philanthropic foundations and the invention of philanthropic traditions, forms, and conventions in the United States during the Gilded Age and Progressive Era. The rapid accumulation of wealth during the late nineteenth and early twentieth centuries posed a series of complex economic, social, and political tensions for the nation following the end of the Civil War, and the invention of the philanthropic foundation by leading businessmen sought to solve those tensions through the planned and systemized redistribution of wealth. This exploration of philanthropy’s history suggests that American capitalists invented a “new” philanthropic tradition in …


La Salud Es Importante: Libro De Actividades (16-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler Oct 2024

La Salud Es Importante: Libro De Actividades (16-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler

Spanish

Health Matters! is a Spanish-language health literacy resource designed for pediatric patients and their families. Written at an approximately 6th-grade reading level, it supports patient education through engaging coloring and activity pages.

This booklet version includes a smaller selection of materials from the larger Health Matters! book. Developed for use in both hospital settings and the broader community, the resource promotes learning through interactive, age-appropriate activities.

This printable PDF version contains the complete collection of activities and comprises 16 pages. The resource was commissioned by Children's Health and prepared by Your Very Favorite.


Synthesis, Spectroscopic, And Characterization Of Novel Nano Sized Mannich Base Complexes With Pt (Iv) And Au (Iii) Ions And Assessing Their Antioxidants Activity, Alya'a J. Ahmed, Mahasin F. Alias Oct 2024

Synthesis, Spectroscopic, And Characterization Of Novel Nano Sized Mannich Base Complexes With Pt (Iv) And Au (Iii) Ions And Assessing Their Antioxidants Activity, Alya'a J. Ahmed, Mahasin F. Alias

Baghdad Science Journal

This study focuses on the synthesis of nano pt(IV) and Au(III) Mannich base complexes derived from ciprofloxacin by the ultrasonic sonication method. The size and morphology of nanocomplex were measured by transmission electron microscopy (TEM), atomic force microscopy (AFM), energy dispersive X-ray (EDX), scanning electron microscopy (SEM), x-ray differentiation (XRD) and Fourier transform infrared spectroscopy (FTIR). Newly synthesized ligand and their metal complexes were tested for their ability to scavenge free radicals at concentrations between 6.25 and 100 µg/ml using their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH). It has been demonstrated that all compounds enhance antioxidant activity in …


Simultaneous Determination Of Lead And Cadmium In Environmental Samples Using Zinc-Diethyldithiocarbamates, Bashar Qasim Oct 2024

Simultaneous Determination Of Lead And Cadmium In Environmental Samples Using Zinc-Diethyldithiocarbamates, Bashar Qasim

Baghdad Science Journal

Toxic metals have a serious impact on the ecological environment. The determination of these metal concentrations provides more information about their toxicity. In this study, a simple, rapid and selective spectrophotometric method with solid phase extraction method has been described for the simultaneous determination of lead (Pb) and cadmium (Cd) in environmental samples using a freshly precipitated zinc-diethyldithiocarbamate (Zn-(DDTC)2) as a reagent. The pre-concentration of Pb and Cd contents was performed according to solid phase extraction process. The determination of Pb+2 and Cd+2 based on the replacement of Zn+2 from the freshly precipitated Zn-(DDTC)2 by Pb+2 and Cd+2 in aqueous …


A Non-Formal Environmental Education Curriculum Using Raptor Ambassadors To Foster Meaningful Relationships Between Diverse Learners Of All Ages And The More-Than-Human World, Danial Davis Oct 2024

A Non-Formal Environmental Education Curriculum Using Raptor Ambassadors To Foster Meaningful Relationships Between Diverse Learners Of All Ages And The More-Than-Human World, Danial Davis

School of Education and Leadership Student Capstone Projects

This capstone project aimed to create an all ages non-formal environmental education curriculum that intentionally fostered connections between Black and Indigenous People of Color (BIPOC) and environmental education and between students of all cultures and the more-than-human world. Research suggested that BIPOC were underrepresented in environmental education programs because many programs were grounded in cultural narratives that overlooked BIPOC perspectives and epistemologies, an injustice known as “ontological distance.” The author’s experience as an educator at The Raptor Center suggested that ambassador raptors such as red-tailed hawks offered highly-engaging subjects for non-formal environmental education activities, particularly for lessons attempting new or …


Comparative Analysis Of Ui Construction And Performance In Android And Flutter Frameworks, Zou Donglan, Mohamad Yusof Darus, Maslina Abdul Aziz, Suzana Zambri Oct 2024

Comparative Analysis Of Ui Construction And Performance In Android And Flutter Frameworks, Zou Donglan, Mohamad Yusof Darus, Maslina Abdul Aziz, Suzana Zambri

Malaysian Journal of Computing (MJoC)

This article examines the process of building user interfaces (UI) using two leading mobile application development tools: Android and Flutter. By developing common login interfaces, the UI construction between these platforms was compared and contrasted. The study highlights key differences in UI elements, design paradigms, and performance metrics, offering a comprehensive analysis. A detailed experimental plan to assess and compare UI development in Flutter and Android was designed, followed by performance evaluations based on metrics such as application size, runtime speed, and memory usage. The findings aim to help beginners quickly grasp and master these tools. Furthermore, the implications for …


Aging In Maynard: A Community Needs Assessment, Caitlin E. Coyle, Mary Krebs Oct 2024

Aging In Maynard: A Community Needs Assessment, Caitlin E. Coyle, Mary Krebs

Center for Social and Demographic Research on Aging Publications

This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA), within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Town of Maynard. The report supports the Council on Aging’s objective to identify and serve the needs of residents age 50 and older. The contents of this report are meant to inform the Town of Maynard, the Maynard Council on Aging (COA), the Senior Center, and organizations that work with and on behalf of older residents of Maynard for the purposes of COA mission fulfillment alongside planning and coordination of …


The Operation Of The Holy Spirit In Pastoral Counseling And Chaplaincy, Elizabeth Canfield Oct 2024

The Operation Of The Holy Spirit In Pastoral Counseling And Chaplaincy, Elizabeth Canfield

Doctor of Ministry (DMin)

The operation of the Holy Spirit in pastoral counseling and chaplaincy is a topic that is difficult to quantify. How and where the Holy Spirit moves is often a mystery. This dissertation seeks to understand the movement of the Holy Spirit in pastoral counseling and chaplaincy in the form of a theological and literature review looking into the history of soul care/pastoral counseling and the development of chaplaincy. It also looks at who the Holy Spirit is, how the Spirit operates, and develops a theology of the Holy Spirit within pastoral counseling and chaplaincy with a focus on spiritual gifts. …


Study Of Vegetated Islands Along The Middle Rio Grande Using Openet Satellite Toolbox, Athena Victoria Sophia Shapiro Esq. Oct 2024

Study Of Vegetated Islands Along The Middle Rio Grande Using Openet Satellite Toolbox, Athena Victoria Sophia Shapiro Esq.

Water Resources Professional Project Reports

Sustainable water management is a challenging issue facing most of the western United States. This study analyzed evapotranspiration predictions at 14 sites along the Middle Rio Grande, changes have occurred over time as these vegetated sand bar islands have developed. Additionally, this study examines the methods of predictions and analysis of evapotranspiration or ET rates along the river using OpenET. An added area of research is the understanding of the presence of vegetation on the sandbar islands. This was analyzed using satellite imaging data from OpenET, which was used to see how changes in vegetation density change ET values seen …


Drinking Water And Wastewater In Socioeconomically Disadvantaged Communities In New Mexico: The Utilization Of Geographic Information Systems To Identify Communities Most In Need Of Technical Assistance, Alejandra Gaytan Tellez Oct 2024

Drinking Water And Wastewater In Socioeconomically Disadvantaged Communities In New Mexico: The Utilization Of Geographic Information Systems To Identify Communities Most In Need Of Technical Assistance, Alejandra Gaytan Tellez

Water Resources Professional Project Reports

The goal of this study is to identify the most burdened New Mexico community water systems (CWSs) and publicly owned treatment works (POTWs) with National Pollutant Discharge Elimination System (NPDES) permits to be able to provide them with technical assistance to address their issues, such as health-based and monitoring and reporting violations. Additionally, technical assistance can help them access federal or state funding to improve the infrastructure within their systems. The study evaluated multiple factors to determine the systems with the highest level of burden and reported the results as value numbers. The CWSs were evaluated on 10 factors that …


Shocking Sentences, John B. Meixner Jr. Oct 2024

Shocking Sentences, John B. Meixner Jr.

Scholarly Works

Harsh recidivist sentencing penalties, like three-strikes laws, have been criticized heavily among both academics and practitioners on a number of different grounds. Most arguments focus on how sentences arising from these penalties are disproportionate—that there is no sensible relationship between the wrong committed and the sentence imposed. Those critiques are valid, but there’s another important problem with recidivist sentencing penalties that has been overlooked: they lead to sentences that are totally unexpected—indeed, shocking—to the defendants who face them. Many recidivist sentencing penalties cause large leaps in sentencing exposure that amount to exponential growth when compared with a defendant’s prior sentences. …


Fall 2024, John M. Pfau Library Oct 2024

Fall 2024, John M. Pfau Library

Peacock – John M. Pfau Library Newsletter

In this issue:

  • Rising Above the Flood: The Library Commons p.1-2
  • The Fantasy and Science Fiction Book Cafe Saga p. 6
  • Great Horned Owls and the Pfau Library p. 8 - 9


Feral Camel, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Feral Camel, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

No abstract provided.


Feral Donkey, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Feral Donkey, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

Donkeys (Equus asinus) were first imported in substantial numbers to Australia in 1866 by Sir Thomas Elder. They were used as pack and draught animals in outlying areas of Western Australia (WA) until the 1930s. They were eventually replaced by the motor vehicle, and unwanted donkeys were released to the wild, where they became feral. The first record of feral donkeys is from the Kimberley in the early 1930s, but it is possible they became feral much earlier.


Blackbird, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Blackbird, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

The introduced common blackbird (Turdus merula) is a pest in eastern Australia. It damages commercial fruit crops and may compete with native birds. The species is prohibited in Western Australia and individuals found here are destroyed.

The Western Australian Organism List (WAOL) contains information on the area(s) in which this pest is declared and the control and keeping categories to which it has been assigned in Western Australia (WA). For more information, see our website at dpird.wa.gov.au.


Feral Goat, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Feral Goat, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

The goat (Capra hircus) was one of the first animals to be domesticated, 8 to 10 thousand years ago. Archaeological work indicates the earliest attempts at domestication were in dry hills surrounding the Mediterranean basin. The ability of goats to utilise the coarse browse of mountainous areas made them suitable for domestication, in preference to sheep. With large-scale domestication of goats throughout the world, goats escaped and established feral goat herds on most continents. Overgrazing by goats has caused severe environmental damage, worldwide.

Goats arrived in Australia with the first fleet. They were introduced to many areas by early settlers …


Rabbit Control: 1080 Versus Pindone, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Rabbit Control: 1080 Versus Pindone, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

There are two toxins available for controlling pest rabbits in Western Australia: 1080 and pindone. This factsheet provides a brief summary of the main characteristics of both vertebrate pesticides. 1080 is generally the preferred toxin for rabbit control in Western Australia (WA).

Any attempt to reduce the impact of rabbits on the productivity of any agricultural enterprise (for example, pasture, crops, tree farms, horticulture) should be undertaken as part of a pest management plan.

This strategy should be proactive rather than reactive to a problem. It should also include a long term strategy for dealing with potential rabbit damage, including …


On The Line And Online: Higher Non-Response To Web-Based Surveys Over-Represents Avid Recreational Fishers Compared With Telephone Surveys, Karina L. Ryan, Steve Taylor, Jeremy M. Lyle, Kate Stark, Sean R. Tracey Oct 2024

On The Line And Online: Higher Non-Response To Web-Based Surveys Over-Represents Avid Recreational Fishers Compared With Telephone Surveys, Karina L. Ryan, Steve Taylor, Jeremy M. Lyle, Kate Stark, Sean R. Tracey

Fisheries Research Articles

Recreational fishing surveys have an important role in providing data to inform fisheries management. The selection of a contact method is an important and often challenging consideration that influences the potential for non-sampling errors that can result in unrepresentative data and biased estimates. Telephones are used for many off-site recreational fishing surveys, but widespread use of digital technology suggests that online surveys could be a viable alternative. We compared phone surveys with alternative online surveys using probability sampling from a licence database. Response rates were lower for online surveys (13%–26%) than phone surveys (97%–98%). The proportion of respondents who reported …


Three-Horned Bedstraw, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Three-Horned Bedstraw, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

Three-horned bedstraw (Galium tricornutum), otherwise known as bedstraw, rough bedstraw, rough fruit corn bedstraw, and corn cleavers, is an annual weed that poses a significant threat to Western Australia’s grains industry. It is a declared pest in Western Australia (WA). A weedy member of the Rubiaceae (madder family), it is closely related to cleavers (Galium aparine)

Bedstraw is a high priority eradication target for Western Australia.


Red Fox, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Red Fox, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

This factsheet provides information on the red fox in Western Australia (WA).

The red fox (Vulpes vulpes) is a native of the northern hemisphere where it occurs throughout most of Europe, Asia, North America, and the northern coast of Africa. The red fox was first introduced to Australia (Victoria) from Britain as early as 1845 for hunting with foxhounds. Having become successfully established in Victoria by about 1870, it colonised most of mainland Australia over the next 70 years. Foxes are not found in the most northern regions of Australia, including northwest Kimberley.

In WA, the fox is a declared …


Rabbit Control: Fumigation, Department Of Primary Industries And Regional Development, Western Australia Oct 2024

Rabbit Control: Fumigation, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity factsheets

Fumigation for rabbit control involves the introduction of poisonous gas into a warren. It is one of the best control methods to use where low numbers of rabbits live in a few widely scattered warrens. The threat to non-target animals is minimal. This factsheet should be read in conjunction with registered product labels and directions for use. Check the Department of Health, Western Australia website (health.wa.gov.au) for public health requirements for the use of phosphine fumigation.

Fumigation may be used in areas where access is limited, such as fence lines, around trees, and on riverbanks, but it may be difficult …


Performance Evaluation Of Ai-Based Healthcare Systems In The United Arab Emirates: A Comparative Analysis Of Diagnostic Accuracy And Predictive Capability Using Spss, Hamad Ismail Oct 2024

Performance Evaluation Of Ai-Based Healthcare Systems In The United Arab Emirates: A Comparative Analysis Of Diagnostic Accuracy And Predictive Capability Using Spss, Hamad Ismail

Theses

This research investigates the opinions and experiences of United Arab Emirates (UAE) healthcare personnel on artificial intelligence (AI)-based technology. Successful application and integration depend on a knowledge of the viewpoints of people at the front-line of patient care as artificial intelligence technology progressively enter healthcare contexts. Combining advanced statistical analysis with quantitative questionnaires using a mixed-methods approach, the study presents a whole picture of artificial intelligence opinions across several healthcare environments and UAE geographical areas. The study revealed a topography of opinions on artificial intelligence in the healthcare sector that is complicated. Though views varied widely based on their employment, …


A Rule Without A Reason: Determining The Capacity For Negligence Of A Person With Mental Illness, Alex Geisinger, David Dematteo, Kellie Wiltsie, Chelsea Jackson Oct 2024

A Rule Without A Reason: Determining The Capacity For Negligence Of A Person With Mental Illness, Alex Geisinger, David Dematteo, Kellie Wiltsie, Chelsea Jackson

William & Mary Law Review

Since the pandemic, the impacts of structural bias on racial minorities and other groups have become an even more compelling concern for legal commentators. One group that has received some attention in the effort to confront bias is the mentally ill. This attention has coincided with a rise in the willingness of individuals to talk about, and destigmatize, mental health issues in society. Yet, despite these efforts, along with a long and well-established body of scholarship that criticizes its treatment of mental illness, the civil law—particularly the law of tort—continues its entrenched refusal to consider mental illness when determining the …


Mixed Ligand Complex: Synthesis, Characterization, And Investigation Of Biomedical Activity, Elaf A. Mousa, Basim I. Al-Abdaly Oct 2024

Mixed Ligand Complex: Synthesis, Characterization, And Investigation Of Biomedical Activity, Elaf A. Mousa, Basim I. Al-Abdaly

Baghdad Science Journal

A new complex, CuCl2.2H2O (M), was synthesized to react with melatonin (L1) and one of the amino acids (L-cysteine, L2) in a mole ratio of (1:1:1) (M: L1:L2) to produce the metal complex. The synthesized complex was then characterized using spectral techniques including infrared (FT-IR), thermal analysis (TG), flame atomic absorption (AAS), micro elemental analysis (CHNS), melting point (m.p.) measurement, and determination of chloride. Octahedral geometry was proposed for the complex. The copper complex was paramagnetic and non-electrolyte. The synthesized complex was evaluated as an antibacterial and antifungal agent against Escherchia coli (G-) and Staphylococcus aureus (G+). fungus Candida. The …


Distinct Landscape And Clinical Implications Of Therapy-Related Clonal Hematopoiesis, Koichi Takahashi, Daisuke Nakada, Margaret Goodell Oct 2024

Distinct Landscape And Clinical Implications Of Therapy-Related Clonal Hematopoiesis, Koichi Takahashi, Daisuke Nakada, Margaret Goodell

Faculty, Staff and Student Publications

Therapy-related clonal hematopoiesis (t-CH) is defined as clonal hematopoiesis detected in individuals previously treated with chemotherapy and/or radiation therapy. With the increased use of genetic analysis in oncological care, the detection of t-CH among cancer patients is becoming increasingly common. t-CH arises through the selective bottleneck imposed by chemotherapies and potentially through direct mutagenesis from chemotherapies, resulting in a distinct mutational landscape enriched with mutations in DNA damage-response pathway genes such as TP53, PPM1D, and CHEK2. Emerging evidence sheds light on the mechanisms of t-CH development and potential strategies to mitigate its emergence. Due to its unique characteristics that predominantly …


Does Glial Lipid Dysregulation Alter Sleep In Alzheimer’S And Parkinson’S Disease?, Lindsey D Goodman, Matthew J Moulton, Guang Lin, Hugo J Bellen Oct 2024

Does Glial Lipid Dysregulation Alter Sleep In Alzheimer’S And Parkinson’S Disease?, Lindsey D Goodman, Matthew J Moulton, Guang Lin, Hugo J Bellen

Duncan NRI Faculty and Staff Publications

In this opinion article, we discuss potential connections between sleep disturbances observed in Alzheimer's disease (AD) and Parkinson's disease (PD) and the dysregulation of lipids in the brain. Research using Drosophila has highlighted the role of glial-mediated lipid metabolism in sleep and diurnal rhythms. Relevant to AD, the formation of lipid droplets in glia, which occurs in response to elevated neuronal reactive oxygen species (ROS), is required for sleep. In disease models, this process is disrupted, arguing a connection to sleep dysregulation. Relevant to PD, the degradation of neuronally synthesized glucosylceramides by glia requires glucocerebrosidase (GBA, a PD-associated risk factor) …


Acute Changes In Liver Function Tests During Initiation Of Ketogenic Diet, Akshat Katyayan, Anuranjita Nayak, Gloria Diaz-Medina, Maureen Handoko, James John Riviello Oct 2024

Acute Changes In Liver Function Tests During Initiation Of Ketogenic Diet, Akshat Katyayan, Anuranjita Nayak, Gloria Diaz-Medina, Maureen Handoko, James John Riviello

Faculty, Staff and Students Publications

BACKGROUND: Ketogenic diet is an effective therapy for patients with medically refractory epilepsy. It is generally well tolerated, with the most common side effects being gastrointestinal. Hepatic toxicity has been described as an uncommon side effect of ketogenic diet, usually with long-term use. However, there are limited data to implicate ketogenic diet in acute liver toxicity.

METHODS AND RESULTS: We analyzed all patients who underwent elective inpatient ketogenic diet initiation at our institution from June 2019 to June 2022. Of the 25 patients reviewed, we found 6 patients who showed acute, asymptomatic changes in liver function tests during initiation, in …