Digital Commons Network^™

Impact Of Irrigation Water Technification On Seven Directories Of The San Juan-Patoa River Using Plithogenic N-Superhypergraphs Based On Environmental Indicators In The Canton Of Pujilí, 2021, Yenson Vinicio Mogro Cepeda, Marco Antonio Riofrío Guevara, Emerson Javier Jácome Mogro, Rachele Piovanelli Tizano

Neutrosophic Sets and Systems

The study analyzed interactions among economic, environmental, and sociocultural factors in agricul-tural irrigation systems to evaluate and promote integral sustainability, using the application of plitho-genic n-SuperHyperGraphs. Significant interactions between vertex attributes were identified during the study's development. Results highlighted that optimizing economic profitability, implementing ecologi-cal pest management, and fostering social cohesion are essential for improving system sustainability. It is concluded that an interdisciplinary approach is critical for achieving comprehensive agricultural sus-tainability, proposing an evaluative model adaptable to local settings to strengthen sector resilience. Ad-ditionally, the application of plithogenic n-SuperHyperGraphs provides a useful tool across various study areas for management and …

Tree Tobacco Extract (Nicotiana Glauca) As A Plithogenic Bioinsecticide Alternative For Controlling Fruit Fly (Drosophila Immigrans) Using N-Superhypergraphs, Emerson Jácome Mogro, Jaime Rojas Molina, Gustavo José Sandoval Cañas, Pablo Herrera Soria

Neutrosophic Sets and Systems

Concern regarding the negative effects of synthetic pesticides has driven the development of bioinsecti-cides as sustainable alternatives. Consequently, Nicotiana glauca has gained prominence for its insecti-cidal properties due to phytochemical compounds effective against pests such as Drosophila immigrans. This study, therefore, evaluated the efficacy of Nicotiana glauca extract as a bioinsecticide by optimizing extraction parameters and analyzing its insecticidal action under laboratory conditions across eight combined treatments. For this purpose, multiple experimental combinations were analyzed through Plithogenic n-SuperHyperGraphs, allowing a multidimensional evaluation of the attributes and proper-ties of each treatment. Results indicated that treatment with 96% ethanol, 48 hours of …

Mixed Graph In Fuzzy, Neutrosophic, And Plithogenic Graphs, Takaaki Fujita, Florentin Smarandache

Neutrosophic Sets and Systems

Graph theory examines networks consisting of nodes (vertices) and the connections (edges) between them. Mixed graphs, which combine both undirected and directed edges, provide a versatile framework for representing relationships with symmetric and asymmetric connections across various systems. In this work, we introduce and analyze the concept of mixed graphs within the contexts of Fuzzy Graphs, Neutrosophic Graphs, and Turiyam Neutrosophic Graphs. By exploring their properties, interrelations, and potential applications, we aim to advance theunderstanding of uncertain graphs.

Fetal Sex Effects On Maternal Health Can Now Be Tested Via Randomization: A First-In-Class Illustration In Cows On Glucoregulatory Outcomes, Aridany Suarez-Trujillo, Colby J Vorland, Griffin T Nicholls, Daniella E Chusyd, Chelsie Parker, Lilian Golzarri-Arroyo, Sophia Swann, Bethany J Funnell, Kara R Stewart, David B Allison

Children’s Nutrition Research Center Staff Publications

Background: The maternal-offspring relationship, such as whether fetal sex influences maternal health, is essential to explore to advance prenatal and maternal health. While associations exist between fetal sex and maternal health outcomes, it is unclear whether these reflect a causal relationship.

Objective: To demonstrate that fetal sex can be randomly assigned to test the causal effect of fetal sex on maternal outcomes.

Methods: Holstein dairy cows were stratified and randomized using sealed opaque envelopes to be artificially inseminated with either X- or Y-sorted bull semen until 40 cows became pregnant. Monthly body weight measurements were recorded, and an intravenous glucose …

Hi3d: Pursuing High-Resolution Image-To-3d Generation With Video Diffusion Models, Haibo Yang, Yang Chen, Yingwei Pan, Ting Yao, Zhineng Chen, Chong-Wah Ngo, Tao Mei

Research Collection School Of Computing and Information Systems

Despite having tremendous progress in image-to-3D generation, existing methods still struggle to produce multi-view consistent images with high-resolution textures in detail, especially in the paradigm of 2D diffusion that lacks 3D awareness. In this work, we present High-resolution Image-to-3D model (Hi3D), a new video diffusion based paradigm that redefines a single image to multi-view images as 3D-aware sequential image generation (i.e., orbital video generation). This methodology delves into the underlying temporal consistency knowledge in video diffusion model that generalizes well to geometry consistency across multiple views in 3D generation. Technically, Hi3D first empowers the pre-trained video diffusion model with 3D-aware …

Don’T Just Say “I Don’T Know”! Self-Aligning Large Language Models For Responding To Unknown Questions With Explanations, Yang Deng, Yong Zhao, Moxin Li, See-Kiong Ng, Tat-Seng Chua

Research Collection School Of Computing and Information Systems

Despite the remarkable abilities of Large Language Models (LLMs) to answer questions, they often display a considerable level of overconfidence even when the question does not have a definitive answer. To avoid providing hallucinated answers to these unknown questions, existing studies typically investigate approaches to refusing to answer these questions. In this work, we propose a novel and scalable self-alignment method to utilize the LLM itself to enhance its response-ability to different types of unknown questions, being capable of not only refusing to answer but also providing explanation to the unanswerability of unknown questions. Specifically, the Self-Align method first employ …

November 2024 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Toe Pad Morphology And Adhesion In The Miniaturized Gecko, Chatogekko Amazonicus (Gekkota: Sphaerodactylidae), Aaron H. Griffing, Juan D. Daza, Stuart V. Nielsen, Fernanda P. Werneck, Patrik F. Viana, Tony Gamble

Biological Sciences Faculty Research and Publications

Chatogekko amazonicus is a miniaturized gecko from northern South America and is among the smallest of toe pad bearing lizards. The toe pads of C. amazonicus are miniscule, between 18% and 27% of the plantar surface area. We aimed to investigate the relationship between adhesive toe pad morphology, body size, and adhesive capabilities. Using scanning electron microscopy, we determine that the adhesive pads of C. amazonicus exhibit branched setae similar to those of other geckos, but that are generally much smaller. When compared with other gecko taxa, we show that C. amazonicus setae occupy a similar range of seta length: …

Effect Of Virtual Reality Technology On Computer Science/Engineering Based Laboratories Education – A Case Study, Mariam A. Al Nuaimi

Theses

Virtual reality (VR) is becoming increasingly popular and essential in education as institutions strive to incorporate technology in education. In Engineering and Computer Science, students face difficulties in comprehending many abstract complex concepts that are typically studied in Labs. This situation worsens with hardware failure and the lack of pedagogical tools. The main goal of this paper is to investigate the impact of VR environments on learning advanced and complex STEM concepts. We also explore the impact of different human-computer interaction (HCI) techniques including gamification on the learning experience of STEM students. To measure such impact, we developed a VR …

Kinetics, Thermodynamics, And Biological Characterizations Of Hydrolysates Enzymatically Produced From Proteins Extracted From Microalgae, Hebah Al-Amodi

Theses

This thesis aims to explore the use of Zeolitic Imidazolate Framework-L (ZIF-L) as a support for immobilizing alcalase and its potency in producing protein hydrolysates. ZIF-L was synthesized at room temperature using an aqueous solution, and alcalase was immobilized through adsorption batch experiment. The successful immobilization of alcalase on ZIF-L was confirmed through Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The maximum adsorption capacity of alcalase on ZIF-L was determined to be 672.1 ± 5.5 mg g^-1 at 40°C using an initial protein concentration of 5 mg mL-1. Adsorption equilibrium data …

Fall 2024, Georgia Library Quarterly

Georgia Library Quarterly

No abstract provided.

Threshold Changes In Winter Temperature And Precipitation Drive Threshold Responses Across Nine Global Climate Zones And Associated Biomes, Alexandra R. Contosta, Kyle A. Arndt, Helen M. Baulch, Nora J. Casson, Adrian Harpold, Toni Lyn Morelli, Alexej P.K. Sirén

Faculty Publications

Globally, winter temperatures are rising, and snowpack is shrinking or disappearing entirely. Despite previous research and published literature reviews, it remains unknown whether biomes across the globe will cross important thresholds in winter temperature and precipitation that will lead to significant ecological changes. Here, we combine the widely used Köppen–Geiger climate classification system with worst-case-scenario projected changes in global monthly temperature and precipitation to illustrate how multiple climatic zones across Earth may experience shifting winter conditions by the end of this century. We then examine how these shifts may affect ecosystems within corresponding biomes. Our analysis demonstrates potential widespread losses …

Medieval Hypebeast: The Conspicuous Consumption Of Joan I Of Aragon, Jonathan Seyfried

Quidditas

Limited releases, celebrity culture, and insane profit margins: these features define the hypebeast phenomenon of the early twenty-first century. The rise and fall of this cycle of conspicuous consumption bears remarkable resemblance to the craze for French culture in the Crown of Aragon in the late fourteenth century. King Joan I, starting from the time of his youth as the Duke of Girona, funded several projects to import French culture. In 1380, Joan married Violante de Bar, niece of the French King Charles V and the Duc de Berry. Once Joan and Violante ascended to the throne, they co-created a …

An Update On Novel Taxa And Revised Taxonomic Status Of Bacteria Isolated From Aquatic Host Species Described In 2022–2023, Claire R. Burbick, Sara D. Lawhon, Brittany Bukouras, Giovanna Lazzerini, Erik Munson

Clinical Lab Sciences Faculty Research and Publications

The description of new taxa and nomenclature updates to currently known taxa from aquatic animal species continues. After a review of the literature from 2022 and 2023, multiple lists of bacteria, including members of Phylum Planctomycetota, were compiled. As with the previous review, most bacteria are oxidase-positive Gram-negative bacilli with familiar families including new taxa in Aeromonadaceae, Flavobacteriaceae, and Vibrionaceae. A number of Gram-positive bacilli are described including new taxa in the Nocardioides, Paenibacillus, and Streptomyces genera. Two anaerobic species are listed, and one new member of Family Planctomycetaceae is noted. Revised taxa are …

Alfred Russel Wallace Notes 32. Wallace On The Tigers Of Singapore, Charles H. Smith

Faculty/Staff Personal Papers

Historian John van Wyhe has written a good deal on Alfred Russel Wallace’s travels in the Malay Archipelago in the 1850s and 1860s, in so doing coming to a number of generally derogative surmises on Wallace’s thoughts and collecting efforts that disagree with the conclusions made by other scholars. In this work one example of such treatment is given, concerning Wallace’s estimation of the number of persons in Singapore attacked by tigers over the middle years of that century.

Loss Of Sc5d Results In Micrognathia Due To A Failure In Osteoblast Differentiation, Chihiro Iwaya, Akiko Suzuki, Junichi Iwata

Faculty, Staff and Student Publications

INTRODUCTION: Mutations in genes related to cholesterol metabolism, or maternal diet and health status, affect craniofacial bone formation. However, the precise role of intracellular cholesterol metabolism in craniofacial bone development remains unclear.

OBJECTIVE: The aim of this study is to determine how cholesterol metabolism aberrations affect craniofacial bone development.

METHODS: Mice with a deficiency in Sc5d, which encodes an enzyme involved in cholesterol synthesis, were analyzed with histology, micro computed tomography (microCT), and cellular and molecular biological methods.

RESULTS: Sc5d null mice exhibited mandible hypoplasia resulting from defects in osteoblast differentiation. The activation of the hedgehog and WNT/β-catenin signaling pathways, …

Verifying Models Of The Underwater Soundscape From Wind And Ships With Benchmark Scenariosa), S Bruce Martin, Martin Siderius, Michael A. Ainslie, Michele B. Halvorsen, Leila Hatch, Mark K. Prior, Daniel Brooker, James Caplinger, Christine Erbe, John Gebbie, Multiple Additional Authors

Electrical and Computer Engineering Faculty Publications and Presentations

Models of the underwater acoustic soundscape are important for evaluating the effects of human generated sounds on marine life. The performance of models can be validated against measurements or verified against each other for consistency. A verification workshop was held to compare models that predict the soundscape from wind and vessels and estimate detection ranges for a submerged target. Eight modeling groups participated in the workshop which predicted sound levels with observation windows of 1 min and 1 km2. Substantial differences were found in how modelers computed the propagation losses for decidecade bands and estimated the source level of wind. …

Inspire : Vol 7 Issue 11, Department Of Medicine

INSPIRE – Department of Medicine Archives

• Message from the Chair
• Medicine at National and International Forums
• Lancet Global Health Commission
• 17th IMEC Neuroendocrine conference
• National BAT Team Workshop on Hyper-Acute Stroke Response
• Navigating the PCO Hormonal Maze
• PCW33 Engage and Inspire | A Master Class in Multimedia Learning
• Healthcare Education | Clinical Simulation
• Featured Fellow: Namra Aziz
• What Academics Are Reading?
• Upcoming Events

Leviathan, Or The Provenance, Construction, And Power Of A Language Ecclesiastical And Invasive, Luna Tobar, Special Collections, Fleet Library

11th Baker & Whitehill Student Artists' Book Contest 2025

Entry for the 11th Baker & Whitehill Student Artists' Book Contest. Opening reception and award ceremony Wednesday, February 19, 2025 at 6:30pm, Fleet Library, Main Reading Room. Juror: Roger S. Williams.

A Randomized Controlled Trial Of Tickoff® (Metarhizium Anisopliae Icipe 7) For Control Of Tick Infestations And Transmission Of Tick-Borne Infections In Extensively Grazed Zebu Cattle In Coastal Kenya, Joseph Wang Ang’A Oundo, Shewit Kalayou, Gerrit Gort, Gebbiena M. Bron, Constantianus J.M. Koenraadt, Quirine Ten Bosch, Daniel Masiga

All Peer-Reviewed Publications

The entomopathogenic fungus Metarhizium anisopliae isolate ICIPE 7 is being developed as an eco-friendly alternative to chemical acaricides in managing natural tick infestation on livestock. Its impact on tick infestation and tick-borne infections in cattle under natural conditions are yet unclear. We conducted a randomized controlled field trial to assess the safety and effects of Tickoff® (a formulation of M. anisopliae isolate ICIPE 7) and the chemical acaricide Triatix® on tick infestation and incidence of Anaplasma marginale and Theileria parva in extensively grazed zebu cattle in coastal Kenya. A total of 217 eligible herds comprising 1459 intent-to-treat zebu cattle were …

Examination Of The Effects Of Various Pharmacotherapies For Diabetes On Nicotine Intake And Pain Sensitivity, Sebastian Ortegon

Open Access Theses & Dissertations

Tobacco use and diabetes are major public health concerns. Prior work has suggested that persons with diabetes may exhibit greater susceptibility to nicotine dependence, and treatments for nicotine cessation are less effective. From existing literature, it is also unclear if neuropathic pain contributes to nicotine use in persons with diabetes. To address these issues, this Masterâ??s thesis first assessed the efficacy of diabetes pharmacotherapies on nicotine intake, food consumption, and water intake in rodent models of insulin resistance (Aim 1). Subsequent studies assessed the impact of analgesic medications on nicotine intake and neuropathic pain in rodent models that produce neuropathic …

Deciphering Rodent Behavior: Unraveling Complex Decision-Making Through High-Throughput Data Analysis In Behavioral Neuroscience, Atanu Giri

Open Access Theses & Dissertations

Understanding the effects of substance use on decision-making is critical for both clinical andtranslational research. In this thesis, I present two complementary studies that explore decision- making behavior in rodents with a focus on alcohol consumption and novel experimental frame- works. The first study examines the impact of acute alcohol consumption on decision-making in a behavioral approach-avoidance task. Rats were presented with a concurrent choice of consuming alcohol and sucrose mixtures across four distinct concentrations, allowing for the analysis of ap- proach or avoidance behavior. Sex-dependent differences emerged, with male rats demonstrating a significantly higher tendency to approach higher alcohol …

Enterococcus Faecium: Evolution, Adaptation, Pathogenesis And Emerging Therapeutics, Yahan Wei, Dennise Palacios Araya, Kelli L. Palmer

School of Podiatric Medicine Publications

The opportunistic pathogen Enterococcus faecium colonizes humans and a wide range of animals, endures numerous stresses, resists antibiotic treatment and stubbornly persists in clinical environments. The widespread application of antibiotics in hospitals and agriculture has contributed to the emergence of vancomycin-resistant E. faecium, which causes many hospital-acquired infections. In this Review, we explore recent discoveries about the evolutionary history, the environmental adaptation and the colonization and dissemination mechanisms of E. faecium and vancomycin-resistant E. faecium. These studies provide critical insights necessary for developing novel preventive and therapeutic approaches against vancomycin-resistant E. faecium and also reveal the intricate interrelationships …

Comparison The Impact Of Co2 And Uvb On Moringa Peregrina And Moringa Oleifera Growth Under Open Top Chamber, Omar Mohammed Alshehhi

Theses

Climate change has had a tremendous impact on ecosystems, with an apparent connection between farming methods and environmental change. Climate change has a substantial effect on both abiotic and biotic factors that affect crop plants. The increasing number of abiotic stressors has highlighted the impact of global warming on plant productivity. This study compared and evaluated the abiotic stress resistance of two Moringa species (Moringa oleifera and Moringa peregrina) to UV radiation, increased CO₂ levels, and their combined effects. The evaluation mainly focused on key morphological features, including plant height (cm) and fresh and dry weights, to assess …

Myths, Stereotypes, And The Problem Of Probative Value: Revisiting The Admissibility Of Criminal Record Evidence, Michelle Biddulph

UBC Law Review

No abstract provided.

Confronting Modern Disaster? British Columbia’S New Emergency And Disaster Management Act, Jocelyn Stacey

UBC Law Review

No abstract provided.

Boosting Acetylcholine Signaling By Cannabidiol In A Murine Model Of Alzheimer's Disease, Hesam Khodadadi, Évila Lopes Salles, Sahar Emami Naeini, Bidhan Bhandari, Hannah M Rogers, Jules Gouron, William Meeks, Alvin V Terry, Anilkumar Pillai, Jack C Yu, John C Morgan, Kumar Vaibhav, David C Hess, Krishnan M Dhandapani, Lei P Wang, Babak Baban

Faculty, Staff and Student Publications

Alzheimer's disease (AD) is a challenging medical issue that requires efficacious treatment options to improve long-term quality of life. Cannabidiol (CBD) is a cannabis-derived phytocannabinoid with potential health benefits, including reports from our laboratory and others showing a therapeutic role in the pre-clinical treatment of AD; however, the mechanisms whereby CBD affects AD progression remain undefined. Innate lymphoid cells (ILCs) are recently discovered immune cells that initiate and orchestrate inflammatory responses. ILC2, a sub-class of ILCs, is proposed to have a role in cognitive function via unknown mechanisms. In this present study, we explored whether CBD ameliorates AD symptoms via …

Role Of The Crosstalk B:Neoplastic T Follicular Helper Cells In The Pathobiology Of Nodal T Follicular Helper Cell Lymphomas, Tania P Sainz, Vishal Sahu, Javier A Gomez, Nicholas J Dcunha, Akshay V Basi, Claudia Kettlun, Iman Sarami, Jared K Burks, Deepa Sampath, Francisco Vega

Faculty, Staff and Student Publications

Angioimmunoblastic T-cell lymphoma (AITL), the most common form of peripheral T-cell lymphoma, originates from follicular helper T (Tfh) cells and is notably resistant to current treatments. The disease progression and maintenance, at least in early stages, are driven by a complex interplay between neoplastic Tfh and clusters of B-cells within the tumor microenvironment, mirroring the functional crosstalk observed inside germinal centers. This interaction is further complicated by recurrent mutations, such as TET2 and DNMT3A, which are present in both Tfh cells and B-cells. These findings suggest that the symbiotic relationship between these 2 cell types could represent a therapeutic vulnerability. …

Genome-Wide Study Of Gene-By-Sex Interactions Identifies Risks For Cleft Palate, Kelsey Robinson, Randy Parrish, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, Carmen J Buxó, Lord J J Gowans, Jacqueline T Hecht, Lina Moreno Uribe, Jeffrey C Murray, Gary M Shaw, Seth M Weinberg, Harrison Brand, Mary L Marazita, David J Cutler, Michael P Epstein, Jingjing Yang, Elizabeth J Leslie

Faculty, Staff and Student Publications

Structural birth defects affect 3–4% of all live births and, depending on the type, tend to manifest in a sex-biased manner. Orofacial clefts (OFCs) are the most common craniofacial structural birth defects and are often divided into cleft lip with or without cleft palate (CL/P) and cleft palate only (CP). Previous studies have found sex-specific risks for CL/P, but these risks have yet to be evaluated in CP. CL/P is more common in males and CP is more frequently observed in females, so we hypothesized there would also be sex-specific differences for CP. Using a trio-based cohort, we performed sex-stratified …

Allosteric Competition And Inhibition In Ampa Receptors, W Dylan Hale, Alejandra Montaño Romero, Cuauhtemoc U Gonzalez, Vasanthi Jayaraman, Albert Y Lau, Richard L Huganir, Edward C Twomey

Faculty, Staff and Student Publications

Excitatory neurotransmission is principally mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-subtype ionotropic glutamate receptors (AMPARs). Negative allosteric modulators are therapeutic candidates that inhibit AMPAR activation and can compete with positive modulators to control AMPAR function through unresolved mechanisms. Here we show that allosteric inhibition pushes AMPARs into a distinct state that prevents both activation and positive allosteric modulation. We used cryo-electron microscopy to capture AMPARs bound to glutamate, while a negative allosteric modulator, GYKI-52466, and positive allosteric modulator, cyclothiazide, compete for control of the AMPARs. GYKI-52466 binds in the ion channel collar and inhibits AMPARs by decoupling the ligand-binding domains from the …