Digital Commons Network^™

Targeted Study Of The Effect Of Yeast Strain On Volatile Compounds Produced In Sorghum Beer, Drew Budner, Joseph Carr, Brett Serafini, Samantha Tucker, Elisabeth Dieckman-Meyer, Lindsey Bell, Katherine A. Thompson-Witrick

Chemistry

An increase in the consumer demand and the availability of gluten-free products has led to several brewers investigating brewing with grains other than barley. The primary grain of choice has been sorghum. These new gluten-free beers have a unique flavor and aroma, which previous research has shown is the result of differences in concentration for key chemical compounds, including ethyl butyrate, butyl acetate, isoamyl acetate, ethyl caproate, hexyl acetate, 1-octanol, nonanal, ethyl octanoate, and ethyl decanoate. This study focused looked at the influence different strains of yeast had on the concentration of these key compounds. Beer was brewed using either …

Oceanic Breakthroughs: Marine-Derived Innovations In Vaccination, Therapy, And Immune Health, Chiara Gamberi, Chad L. Leverette, Alexis C. Davis, Moayad Ismail, Ilaria Piccialli, Nicola Borbone, Giorgia Oliviero, Caterina Vicidomini, Rosanna Palumbo, Giovanni N. Roviello

Biology

The vast, untapped potential of the world’s oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as Nannochloropsis spp. and Dunaliella salina are emerging as resources for recombinant vaccine development with specific and heterologous genetic tools used to boost production of functional recombinant antigens in Dunaliella salina and Nannochloropsis spp. to induce immunoprotection. In humans, several antigens produced in microalgae have shown potential in combating diseases caused by the human papillomavirus, human immunodeficiency virus, hepatitis B virus, influenza virus, Zika virus, Zaire Ebola virus, Plasmodium falciparum, and Staphylococcus aureus. For animals, microalgae-derived vaccine prototypes have been developed …

Exploring The Structure Of Space Science Research In Mexico Using Science Mapping Tool: Citespace., Ibis Anette Moreno-Lozano, Humberto Carrillo-Calvet, Jose Luis Jiménez-Andrade, Ricardo Arencibia-Jorge

UTA Libraries Staff Publications - Archive

This paper presents an analysis of the knowledge structure of the Mexican scientific community in the field of Space Science in Web of Science, between 2000 and 2019. CiteSpace software helped to identify the influential papers in the domain. The findings of this study shed light on the historical development of Space Science in Mexico and highlight the country's scientific performance with the worldwide trend. Moreover, the study emphasized the importance of bibliometrics in understanding the scientific undercurrents of a discipline. By analyzing co-citation networks, the study identified prominent clusters and research fronts in the field, providing valuable insights into …

Summary Of The Second Symposium: Japan's Response To The War, Shigeyuki Mori

New England Journal of Public Policy

Summary of the Second Symposium: Japan's Response to the War. Volume 36, Issue 2 of the New England Journal of Public Policy.

A Comparative Study Of Weavings Of Two Disparate Cultures: Finding The Similarities In Handcrafts, Monica Lowe

Theses

This thesis is a study of the similarities between the traditional weavings of two indigenous cultures who appear to be culturally unrelated, the West African Ewe and the Peruvian Quechua located in the Cusco Province. Its purview includes the purpose it serves, who does the craft, and meanings woven into the textiles. The focus of this thesis is based on a theory that across human cultures, iconographies and archetypes are demonstratively the same, with similar collective, unconscious meanings. The overall theory is that handcrafts are an important consideration when demonstrating a reflection of human cultural similarities in beliefs, community, and …

Digital Creative Portfolios As New Spaces For Professional Interaction, Verónica Meléndez Valoria

Artículos científicos

Since the advent of digital platforms that allowed creatives to publicly showcase their portfolios, some of these platforms have evolved beyond their original models. They have transitioned from mere exhibitions to more commercialized and interactive spaces. In these environments, any creative individual can not only display their work but also promote their brand and establish diverse connections, much like any other social network. The article aims to identify key elements and causes of this transformation. Additionally, it seeks to explain the position these platforms hold in relation to other domains. Lastly, it intends to extract implications and unresolved questions for …

Taxonomía De Animación Funcional En Diseño De Interfaces: Validación En El Ámbito Educativo, Raquel Ávila Muñoz, Jorge Clemente Mediavilla, María José Pérez-Luque

Artículos científicos

En este artículo se presentan los resultados de la etapa final del proceso de validación de la taxonomía de animación funcional (TAF). Esta clasificación recoge las funciones que puede ejercer la animación, como componente del diseño visual de una interfaz, para mejorar la usabilidad y lograr una experiencia de usuario óptima. Esta taxonomía se ha desarrollado con el objeto de proporcionar una herramienta que ayude a evitar los usos de la animación potencialmente negativos sobre los que alertan los expertos en usabilidad. Tras una primera fase de validación, llevada a cabo entre expertos, en esta segunda fase se analiza la …

News From Uab Libraries, 11 2024, Uab Libraries

UAB Libraries News

No abstract provided.

Seasonal Variation In Atp-Induced Retinal Damage In The Cone-Dominant 13-Lined Ground Squirrel, Owen R. Bowie, Hannahm Follett, Ching Tzu Yu, Chloe Guillaume, Phyllis M. Summerfelt, Nicole Manfredonia, Jenna Grieshop, Dana K. Merriman, Sergey Tarima, Joseph Carroll

Biostatistics Faculty Publications

Purpose: To examine whether time of year (relative to hibernation emergence) influences the retinal degenerative effects of intravitreal injection of adenosine triphosphate (ATP) in the 13-lined ground squirrel (13-LGS). Methods: Eighteen (9 male, 9 female) 13-LGS in three experimental cohorts (early season, mid-season, late season) (n = 6 each) underwent baseline imaging using scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT). Animals then received a 10-μL intravitreal injection of 0.723 M ATP, followed by OCT and SLO imaging at 3, 10, and 21 days. Adaptive optics SLO (AOSLO) was performed in animals without retinal damage after the 21-day follow-up. …

A Method For Teaching Biostatisticians To Write And Critique Specific Aims, Jesse D. Troy, Gregory P. Samsa, Megan L. Neely, Steven C. Grambow, Sarah Peskoe, Emily Slade, Gina Maria Pomann

Biostatistics Faculty Publications

This article describes the design of a single instructional module on writing and critiquing the Specific Aims (SA) section of a grant proposal for a biomedical research study. It begins by discussing the goals and learning objectives for the module. Then, it discusses the typical structure of a SA section to orient readers to the core content. This method is rooted in using an established framework for scientific writing, which is presented in brief, along with examples of how it applies to writing the SA section. Then, the structure of the instructional module is described, including the exercises for participants. …

Reimagining Learning: Overcoming Barriers To Effective Edtech Tools Adoption In K-12 Schools, Nunzia Del Vento

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Teaching in K-12 education faces significant challenges in effectively integrating Educational Technology (EdTech) tools into classrooms. Despite the transformative potential of EdTech for enhancing student engagement, personalizing instruction, and developing critical skills, educators encounter barriers such as inadequate training, overwhelming choice, and uncertainty about tool effectiveness. This study investigated the criteria used by K-12 teachers in selecting EdTech tools, the support and training they receive, and their perceptions of tool effectiveness. Employing a mixed-methods approach combining quantitative surveys and qualitative responses, data was gathered from educators in Florida, highlighting their diverse roles, preferences, and challenges in adopting EdTech tools. Findings …

Geosciences Affiliated Publications: Snapshot Of The Research Publications 2018-2023, Danna Jaimes-Fajardo, Jeremy J. Smith, Lutishoor Salisbury

University Libraries Faculty Publications and Presentations

This report provides a snapshot of the research publications for authors affiliated with the Geosciences department at the University of Arkansas, Fayetteville, for the period 2018-2023. It includes publications by material type; co-author characteristics; ranking of journals according to journal citation reports.

Research Gaps And Priorities For Quantitative Microbial Risk Assessment (Qmra), Kerry A. Hamilton, Joanna Ciol Harrison, Jade Mitchell, Mark Weir, Marc Verhougstraete, Charles N. Haas, A. Pouyan Nejadhashemi, Julie Libarkin, Tiong Gim Aw, Kyle Bibby, Aaron Bivins, Joe Brown, Kara Dean, Gwyneth Dunbar, Joseph N.S. Eisenberg, Monica Emelko, Daniel Gerrity, Patrick L. Gurian, Emma Hartnett, Michael Jahne, Rachael M. Jones, Timothy R. Julian, Hongwan Li, Yanbin Li, Jacqueline Mac Donald Gibson, Gertjan Medema, J. Scott Meschke, Alexis Mraz, Heather Murphy, David Oryang, Emmanuel De Graft Johnson Owusu-Ansah, Emily Pasek, Abani K. Pradhan

Faculty Publications

The coronavirus disease 2019 pandemic highlighted the need for more rapid and routine application of modeling approaches such as quantitative microbial risk assessment (QMRA) for protecting public health. QMRA is a transdisciplinary science dedicated to understanding, predicting, and mitigating infectious disease risks. To better equip QMRA researchers to inform policy and public health management, an Advances in Research for QMRA workshop was held to synthesize a path forward for QMRA research. We summarize insights from 41 QMRA researchers and experts to clarify the role of QMRA in risk analysis by (1) identifying key research needs, (2) highlighting emerging applications of …

Bard Observer, Vol. 23, No. 5 (November 2024), Bard College

Bard Observer, 2020 - 2029

No abstract provided.

Pigs And The City, Sayd Randle

Asian Management Insights

Urban greening requires a re-look at sharing space with animals and nature.

1. There are several challenges when balancing urban development with ecological sustainability, as seen in Singapore’s struggles with human-wildlife interactions like wild boars entering populated areas.

2. Opinions on managing wildlife diverge between calls for stricter population control and concerns over habitat loss. This shows the need for balanced approaches that cater to both humans and ecology alike.

3. Cities like Houston, Barcelona, and Hong Kong offer different models for human-wildlife management, showing that local contexts shape approaches to achieving peaceful coexistence with urban wildlife.

Donald Griffin, Sentience, And Animal Research Ethics, John Gluck

Animal Sentience

Recollection of early encounters with Donald Griffin’s pioneering work on animal awareness, provoking intense, often hostile academic responses, later forgotten.

Attention Deficit Hyperactivity Disorder, Cannabis Use, And The Endocannabinoid System: A Scoping Review, Jennie Ryan, Mitchell Fruchtman, Andrea Sparr-Jaswa, Amy Knehans, Brooke Worster

Department of Medicine Faculty Papers

There is emerging evidence that the endocannabinoid system (ECS) plays a significant role in the pathophysiology of many psychiatric disorders, including attention deficit hyperactivity disorder (ADHD). Increasing evidence suggests that a number of neurobiological correlates between endogenous cannabinoid function and cognitive dysfunction are seen in ADHD, making the ECS a possible target for therapeutic interventions. Cannabis use and cannabis use disorder are more prevalent in individuals with ADHD, compared to the general population, and there is growing popular perception that cannabis is therapeutic for ADHD. However, the relationship between cannabis use and ADHD symptomology is poorly understood. Further understanding of …

Community Perspectives Of Heat And Weather Warnings For Pregnant And Postpartum Women In Kilifi, Kenya, Adelaide Lusambili, Veronique Filippi, Britt Nakstad, Julian Natukunda, Cathryn Birch, John Marsham, Nathalie Roos, Peter Khaemba, Sari Kovats

Institute for Human Development, East Africa

Background: Extreme weather is a recognised risk factor for stillbirth and preterm birth, disrupts women’s access to healthcare during pregnancy and childbirth, and negatively affects the care of newborns. Reliable and accessible heat and weather warning systems are key in alerting individuals to undertake protective measures. There is a notable gap in understanding how women and caregivers in rural East Africa perceive and utilize weather information. We investigated community members’ heat and weather warning information-seeking behaviour, identified available sources, assessed their reliability and utility, and examined their influence on behaviour.

Settings: Our research was conducted in rural Kilifi County in …

Dementia Risk Reduction In The African Context: Multi-National Implementation Of Multimodal Strategies To Promote Healthy Brain Aging In Africa (The Africa-Fingers Project), Chinedu Momoh, Rachel Maina, Lukoye Atwoli, Karen Blackmon, Edna Bosire, Gloria Chemutai, Linda Khakali, Sylvia Mbugua, Zul Merali, Olivera Nesic Taylor,, Anthony Ngugi, Cyprian Mostert, Eunice Muthoni, Roselyter Riang’A, Mansoor Saleh, Shahin Sayed, Jasmit Shah

Brain and Mind Institute

Dementia prevention in Africa is critically underexplored, despite the continent's high prevalence of modifiable risk factors. With a predominantly young and middle-aged population, Africa presents a prime opportunity to implement evidence-based strategies that could significantly reduce future dementia cases and mitigate its economic impact. The multinational Africa-FINGERS program offers an innovative solution, pioneering culturally sensitive, multidomain interventions tailored to the unique challenges of the region. Leveraging insights from landmark global studies such as Worldwide-FINGERS and Alzheimer's Disease Neuroimaging Initiative, the program employs a multideterminant precision prevention framework, grounded in community based systems dynamics. Africa-FINGERS further integrates cutting-edge state-of-the-art multimodal biomarker …

Law Library Blog (November 2024): Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.

Anti-Egfr Aptamer Exhibits Direct Anti-Cancer Effects In Nsclc Cells Harboring Egfr L858r Mutations, Brian J. Thomas, Sania Z. Awan, Trupti Joshi, Mark A. Daniels, David Porciani, Donald H. Burke

Biomedical Sciences

Non-small cell lung cancer (NSCLC) adenocarcinoma (LUAD) is a leading cause of death worldwide. Activating mutations in the tyrosine kinase domain of the oncogene epidermal growth factor receptor (EGFR) are responsible for ~10–50% of all LUAD cases. Although tyrosine kinase inhibitors (TKIs) have been effective in prolonging patient survival and quality of life, acquired resistance and disease progression are inevitable, presenting a clear unmet need for alternative or adjuvant therapeutics. Here we show that an anti-EGFR aptamer (EGFRapt) decreases viability and tumor growth of LUAD cell lines harboring the L858R ± T790M mutation in EGFR. Additionally, we elucidate …

Small And Long Non-Coding Rna Analysis For Humantrophoblast-Derived Extracellular Vesicles And Their Effect On The Transcriptome Profile Of Human Neural Progenitor Cells, Jessica A. Kinkade, Pallav Singh, Mohit Verma, Teka Khan, Toshihoko Ezashi, Nathan J. Bivens, R. Michael Roberts, Trupti Joshi, Cheryl S. Rosenfeld

Biomedical Sciences

In mice, the fetal brain is dependent upon the placenta for factors that guide its early development. This linkage between the two organs has given rise to the term, the placenta–brain axis. A similar interrelationship between the two organs may exist in humans. We hypothesize that extracellular vesicles (EVs) released from placental trophoblast (TB) cells transport small RNA and other informational biomolecules from the placenta to the brain where their contents have pleiotropic effects. Here, EVs were isolated from the medium in which human trophoblasts (TBs) had been differentiated in vitro from induced pluripotent stem cells (iPSC) and from cultured …

Sela News

The Southeastern Librarian

No abstract provided.

As Punishment For Arrests: Involuntary Servitude Under The Housekeeping Exception To The Thirteenth Amendment, Elissa Bowling

Minnesota Law Review Vols. 106:2 onward (2021-present)

The Thirteenth Amendment reads: “Neither slavery nor involuntary servitude, except as a punishment for crime whereof the party shall have been duly convicted, shall exist within the United States, or any place subject to their jurisdiction.” Yet, in contemporary American jails and prisons, pretrial detainees have been forced to perform work for these carceral facilities despite not being convicted of a crime. When tasked with assessing the constitutionality of such pre-conviction labor policies, courts employed a narrow reading of the Thirteenth Amendment and ruled that jails and prisons can compel pretrial detainees to perform maintenance and operational tasks under the …

Chronologically Inappropriate Morphogenesis (Chinmo) Is Required For Maintenance Of Larval Stages Of Fall Armyworm, Xien Chen, Jinmo Koo, Surjeet Kumar Arya, Subba R. Palli

Entomology Faculty Publications

Broad complex (Br-C) and eip93F (E93) transcription factors promote insect metamorphosis from larva to pupa and from pupa to adult, respectively. Recently, chronologically inappropriate morphogenesis (Chinmo) has been proposed as a larval specifier in Drosophila melanogaster. However, whether Chinmo is required for larval maintenance in lepidopteran insects, the underlying mechanisms involved in maintaining the larval stage, and its interactions with the JH signaling pathway are not well understood. Here, we used a binary transgenic CRISPR/Cas9 system to knockout Chinmo and Kr-h1 (primary response gene in the JH signaling pathway) in the fall armyworm (FAW). Kr-h1 knockout induced premature metamorphosis only …

The History Of St. Michael’S Seminary In The Diocese Of Pittsburgh, John C. Bates Esq.

Gathered Fragments

No abstract provided.

Spreading Hope On Tiktok, Lake Union Conference Of Seventh-Day Adventists

Lake Union Herald

No abstract provided.

Recurrent Endothelin-1 Mediated Vascular Insult Leads To Cognitive Impairment Protected By Trophic Factor Pleiotrophin, Mayank Pushpam, Ankita Talukdar, Shobha Anilkumar, Shashank Kumar Maurya

Open Access archive

Vascular dementia (VaD) is a complex neurodegenerative condition, with cerebral small vessel dysfunctions as the central role in its pathogenesis. Given the lack of suitable animal models to study the disease pathogenesis, we developed a mouse model to closely emulate the clinical scenarios of recurrent transient ischemic attacks (TIAs) leading to VaD using vasoconstricting peptide Endothelin-1(ET-1). We observed that administration of ET-1 led to blood-brain barrier (BBB) disruption and detrimental changes in its components, such as endothelial cells and pericytes, along with neuronal loss and synaptic dysfunction, resulting in irreversible memory loss. Further, in our pursuit of understanding potential interventions, …

Bacterial Lipopolysaccharide Model Of Neuroinflammation-Associated Neurodegeneration In Wistar Rats: A Comparison Between Different Durations Of Lipopolysaccharide Induction, Vandana Blossom, Sheetal Dinkar Ullal, Rajalakshmi Rai, Shrijeet Chakraborthi

Open Access archive

Background and Aim: Bacterial lipopolysaccharide (LPS)-induced neuroinflammation can be the most dependable animal model for studying neurodegeneration mechanisms driven by systemic inflammation-induced neuroinflammation. Hence, this study aimed to standardize the LPS model of neuroinflammation by comparing the effect of relatively low-dose LPS administered for different durations on the induction of neurodegeneration in Wistar rats. Materials and Methods: Six groups of six adult Wistar rats per group were used in the study. Group 1 was the control group, and the other five were administered single weekly dose of LPS (170 µg/kg) for increasing durations, ranging from 4 weeks to 8 weeks. …

A Novel Statistical Approach To Obtain The Best Visibility Slice In Mri Sequence Of Brain Tumors, Hassan Al-Yassin, Mohammed A. Fadhel, Omran Al-Shamma

Baghdad Science Journal

Early diagnosis of brain tumor enhances the possibility of patients being cured. With the progress of the use of artificial intelligence in the medical field, the detection of brain tumors has become one of the researchers’ interests. Obtaining which slice in the MRI sequence gives the best visibility of the tumor is still a challenge. This paper introduced a novel statistical approach to extracting the tumor from the patient's MRI scan (sequence). Initially, the probability mass function (PMF) was computed for each image in the sequence. Then, the Kullback-Leibler divergence technique was applied to determine the tumor image(s) that diverged …