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Epigenetics And Character Virtue Development, David S. Moore

Pitzer Faculty Publications and Research

Current understandings of epigenetics offer some insights into the developmental origins of character virtues. Research on epigenetics has demonstrated that phenotypes depend on both genomic and non-genomic information for their development, and such is true for the development of character virtues as well. This conclusion offers significant support for the Developmental Systems perspective. Although researchers have not yet studied the role of molecular epigenetic factors in the development of character, the field of behavioral epigenetics has revealed how such factors contribute to psychological and other behavioral phenotypes in general. In particular, behavioral epigenetics research can highlight the plasticity of human …

Older Adult Compendium Of Physical Activities: Energy Costs Of Human Activities In Adults Aged 60 And Older, Erik A. Willis, Stephen D. Herrmann, Mary Hastert, Chelsea L. Kracht, Tiago V. Barreira, John M. Schuna Jr., Zhenghua Cai, Minghui Quan, Scott A. Conger, Wendy J. Brown, Barbara E. Ainsworth

Kinesiology Faculty Publications and Presentations

Purpose: To describe the development of a Compendium for estimating the energy costs of activities in adults ≥60 years (OA Compendium).

Methods: Physical activities (PAs) and their metabolic equivalent of task (MET) values were obtained from a systematic search of studies published in 4 sport and exercise databases (PubMed, Embase, SPORTDiscus (EBSCOhost), and Scopus) and a review of articles included in the 2011 Adult Compendium that measured PA in older adults. MET values were computed as the oxygen cost (VO₂, mL/kg/min) during PA divided by 2.7 mL/kg/min (MET₆₀₊) to account for the lower resting metabolic rate …

Dual Gallium Drug Treatment Against Carbapenem-Resistant Klebsiella Pneumoniae: Efficacy And Potential Mechanism(S) Of Action And Resistance, Zachary Scott, Seoung-Ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy

Journal Articles: Pathology and Microbiology

Klebsiella pneumoniae (KLP) is a Gram-negative pathogen that can be highly antibiotic-resistant. Our group has worked with gallium-based compounds as a means of treating bacterial infections. Here the possible mechanism is investigated for dual therapy comprised of gallium nitrate (Ga(NO₃)₃) and gallium protoporphyrin (GaPP) on KLP. It is found that in vitro the combination of Ga(NO₃)₃ and GaPP is synergistic against KLP. The in vivo efficacy is of the dual therapy is additionally tested by treating pulmonary KLP infections in mice. Much greater effectiveness are observed in bacterial clearance and survival of mice …

Tetracycline And Oxacillin Act Synergistically On Biofilms And Display Increased Efficacy In Vivo Against Staphylococcus Aureus, Amy K. Tooke, Rebecca E. Hodges, Josie F. Pyrah, Kenneth W. Bayles, Stephen A. Renshaw, Simon J. Foster

Journal Articles: Pathology and Microbiology

Oxacillin (bactericidal) and tetracycline (bacteriostatic) are clinically relevant antibiotics that are routinely prescribed to treat Staphylococcus aureus infections but not conventionally used in combination. There is an urgent need for treatment regimens that can act upon biofilms during infection, associated with chronic infections on indwelling devices, as well as acute planktonic (systemic) infection. Here we show that in an in vitro model oxacillin and tetracycline act synergistically against S. aureus UAMS-1 biofilms, reducing the concentration of both antibiotics necessary to eradicate an established biofilm. Using an in vivo zebrafish larval infection model with S. aureus NewHG, they display improved bacterial …

How Does Plasma L-Fabp Level Correlate With Cardiovascular Disease Risk In Patients With Chronic Kidney Disease, And Can It Serve As A Reliable Biomarker For Risk Stratification?”, Nehad Refat Ibrahim, Ghadir Elsawy

Journal of Medicine in Scientific Research

Chronic kidney disease (CKD) affects up to 10% of the global adult population, with cardiovascular disease (CVD) being a major concern. CKD patients face increased CVD-related morbidity and mortality. While the exact mechanisms linking CKD and CVD are complex, traditional risk factors (e.g., diabetes, hypertension) and nontraditional factors (e.g., inflammation, oxidative stress) play a role. Liver-type fatty acid-binding protein (L-FABP) is associated with lipid metabolism and kidney injury. Few studies suggest L-FABP as a potential biomarker for CVD risk in CKD patients, but further research is needed to fully understand its role. This study aims to explore the link between …

Les Écritures De Soi Entre Identité Éclatée Et Identité Réconciliée. Une Herméneutique De La Pratique Autobiographique Intellectuelle Chez Maryse Condé Et Henri Lopes, Gervais Désiré Yamb

Présence Francophone: Revue internationale de langue et de littérature

This article aims at analyzing the heuristic status of self-writing through the articulation of shattered and reconciled identity in La vie sans fards (2012) of Maryse Condé and Ma grand-mère bantoue et mes ancêtres les Gaulois (2003) by Henri Lopes. In fact, we argue that the articulation in question, here, appears as writing for oneself and for others, which is based on a hermeneutical perspective of the self and the sociality of texts proposed by Paul Ricoeur and Claude Duchet. The main objective of this investigation is to understand, in Condé and Lopes writings, the practice of intellectual autobiography as …

Biotin For Hair Loss: Teasing Out The Evidence, Allyson Yelich, Hannah Jenkins, Sara Holt, Richard Miller

West Florida Division GME Research Day 2024

No abstract provided.

2-Methyl-2-Butanol (2m2b) Ingestion Related Toxicity, Elizabeth Diaz, Darshan B. Bhatty, Ngoc Vu, Sathish Karmegam

North Texas GME Research Forum 2024

2-methyl-2-butanol known as Tert-amyl alcohol (TAA) was previously used in the past for its hypnotic, anticonvulsant, and sedative properties.1 Both ethanol and 2M2B stimulate GABA-A receptors causing similar CNS effects.1 Animal studies have shown that toxicity is greater than 2-pentanol, 3-methyl-1-butanol, and ethanol1. 2M2B is replacing ethanol due to its low cost per dose, high potency, and does not produce a hangover as it is not metabolized to aldehydes.1 This case report describes the clinical course of a patient after intoxication with 2M2B and bringing awareness as it is difficult to confirm diagnosis since there are no specific clinical features …

Multidisciplinary Simulation-Based Trauma Education For General Surgery Interns, Jennifer Austin, April Miller, Jeremiah Avarana, Alicia Lay

North Texas GME Research Forum 2024

Introduction: According to the American Society of Gastroenterology Endoscopy (ASGE), choledocholithiasis is defined as the presence of gallstones in biliary tree. Choledocholithiasis is concomitantly present in approximately 1 to 10 percent of patients with cholelithiasis. Choledocholithiasis can be described as small <15 >mm, large >15 mm, and difficult due to anatomic location, impaction, or unusual hardness/ shape. Choledocholithiasis is managed endoscopically with large balloon papillary dilation, cholangioscopy-guided intraductal laser and electrohydraulic lithotripsy (EHL), and escalation to laparoscopic common bile duct exploration, if endoscopic procedures fail. Thus far, there are sparse studies that show the requirement of choledochotomy in large and …

Donut Hole Summer 2024, Medicare Donations & Design Committee

Donut Hole Newsletter

No abstract provided.

Risk Avoidance During Dispersal: Temporal And Behavioral Shifts In Selection By Non-Resident Eastern Wolves, C. A. Thompson, J. F. Benson, B. R. Patterson

School of Natural Resources: Faculty Publications

No abstract provided.

Parnassus 2024: Thresholds

Parnassus

No abstract provided.

2024 Annual Report, Tennessee. Division Of Forestry And Tennessee. Department Of Agriculture

Forestry Annual Reports

This annual report presents an overview of Tennessee Forestry Commission programs and management.

Town Of Merrimack, 1746, New Hampshire 2023 Annual Report., Merrimack Town Representatives

Merrimack, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

The Impact Of Sublethal Injuries On Mountain Lion Predation And Spatial Ecology, J. F. Benson

School of Natural Resources: Faculty Publications

No abstract provided.

Snapshot Usa 2021: A Third Coordinated National Camera Trap Survey Of The United States, J. F. Benson Et Al.

School of Natural Resources: Faculty Publications

No abstract provided.

Humans Drive Spatial Variation In Mortality Risk For A Threatened Wolf Population In A Canis Hybrid Zone, J. F. Benson, P. J. Mahoney, T. J. Wheeldon, C. A. Thompson, M. E. Ward, A. D. Mclaren, G. E. Desy, J. M. Fryxell, B. R. Patterson

School of Natural Resources: Faculty Publications

No abstract provided.

Annual Report Of The Wally Cordes Teaching And Faculty Support Center For The Year Ended…2024, University Of Arkansas, Fayetteville. Wally Cordes Teaching And Faculty Support Center

Wally Cordes Teaching and Faculty Support Center Annual Report

No abstract provided.

Small Airway-On-A-Chip Enables Analysis Of Human Lung Inflammation And Drug Responses In Vitro, Christina A. Fernandez

VCU's Medical Journal Club: The Work of Future Health Professionals

This presentation focuses on the development of the Small Airway-on-a-Chip, a microfluidic device meant to serve as a more accurate, human-relevant research model for lung inflammation-focused pharmaceutical testing, as described in Small Airway-on-a-Chip Enables Analysis of Human Lung Inflammation and Drug Responses in Vitro by Benam et al. Currently, there is no way to study organ-level complexities of human lung inflammation outside of the clinical setting. However, the human lung Small Airway-on-a-Chip demonstrated the ability to reconstitute a functional unit of the lung as well as model asthma, lung inflammation, and Chronic Obstructive Pulmonary Disease (COPD), suggesting that the device …

History Newsletter 2023-24, Department Of History

Department of History Archives

No abstract provided.

Intraparty Conflict And The Separation Of Powers, Gregory A. Elinson

College of Law Faculty Publications

Intent on reconciling constitutional theory to political reality, public law scholars have in recent decades dismissed as naïve both the logic of the Constitution’s design set forth in The Federalist and the Framers’ dismal view of political parties. They argue that contrary to the Madisonian vision competition between our two national political parties undergirds the horizontal and vertical separation of powers. But, in calling attention to the fights that take place between political parties, they underestimate the constitutional significance of the conflicts that persist within them. Reconsidering the law and theory of the separation of powers with attention to intraparty …

Wildfire And Asylum: A Terrapsychological Approach To Backyard Pilgrimage, Jacob Kaminker

International Journal of Transpersonal Studies

This paper offers a conceptual framework and embodied practice of finding ones’ psychological roots through mythological re-emplacement. The author utilizes the lenses of depth psychology, terrapsychology, ritual and pilgrimage. The method also focuses on experiences of awe in nature as a catalyst for transpersonal experience. This deeply personal account offers a model for the reader’s own symbolic engagement with the physical, natural and historically rich world around them.

The Bible In Its Context : How To Improve Your Study Of The Scriptures, Craig Keener

Academic Books

No abstract provided.

Toolkit To Address Free-Ranging Domestic Cats On Agency Lands Managed For Native Wildlife And Ecosystem Health, Sara H. Schweitzer, Colin M. Gillin

Human–Wildlife Interactions Monographs

Native flora and fauna of North America face numerous threats, and impacts from invasive species are some of the most challenging. Free-ranging domestic cats (Felis catus) are extremely harmful to wildlife and the environment. The Association of Fish and Wildlife Agencies (AFWA) developed a toolkit to provide guidance to fish and wildlife agencies as they address free-ranging domestic cats on agency lands managed for native wildlife and ecosystem health. Topics in this document include wildlife conservation, infectious diseases, legal issues, education and outreach, human dimensions, partnerships, management strategies, and model regulatory and legal language. This toolkit is not …

Implementation Of The Stop The Bleed Program At A Local Park District, Emily J. Minerva

Doctor of Nursing Practice Scholarly Projects

Background: Fifty percent of people who suffer from an acute bleeding event die before arriving to the hospital due to lack of receiving care in a timely manner.

Local Problem: Increased emergency response times could prove fatal to someone experiencing a large bleed, highlighting the need for increased emergency preparedness in the community.

Methodology: This implementation pilot project utilized quantitative tools (pre- and post-multiple-choice test and Likert scales) and a qualitative narrative approach (inductive content analysis).

Interventions: A certified Stop the Bleed instructor provided Stop the Bleed education with an animated presentation, hands-on skills training session, and a …

The Town Of Wentworth, New Hampshire Annual Report 2023., Wentworth Town Representatives

Wentworth, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Individual Variation In Undergraduate Student Metacognitive Monitoring And Error Detection During Biology Model Evaluation, J. T. Dauer

School of Natural Resources: Faculty Publications

No abstract provided.

The Choroid Plexus Links Innate Immunity To Dysregulation Of Csf Homeostasis In Diverse Forms Of Hydrocephalus, Emre Kiziltug

Yale Medicine Thesis Digital Library

The choroid plexus (ChP) secretes a half-liter/day of cerebrospinal fluid (CSF) and is the blood-CSF barrier with critical immune functions. Hydrocephalus, commonly caused by infection or hemorrhage, lacks non-surgical treatments due to obscure pathobiology. We hypothesize that in acquired hydrocephalus, the dual ChP functions of CSF secretion and blood-CSF barrier maintenance become pathologically entangled in a maladaptive disease state. To test this hypothesis, we created novel rat models of post-infectious (PIH) and posthemorrhagic hydrocephalus (PHH) and conducted a multi-omics investigation of these animals to dissect the cellular, molecular, and physiological pathology underlying PIH and PHH . Our systems approach combined …

Biodigestor Functionality And Commercialization Of Organic Fertilizer For Smallholder And Productive Farms In Kenya, Jessica Garofalo, Mia Ingram

Miller Center Fellowship

Agriculture has a long history in Kenya with roots of both sustenance farming and commercial farming. Agriculture used to make up over two fifths of their GDP and while that number has shrunk, it still makes up around one fifth of the economy making it an important part of the job market. Subsistence farming is still a prevalent way of life in Kenya, especially in more rural areas. As a whole, the Kenyan agricultural industry employs and nourishes a large portion of the nation’s population and yet, in light of climate change, more and more farmers have become reliant on …

Capstone Project, Megan Gaeth

Regis University Student Publications (comprehensive collection)

Human-wildlife conflict is increasing globally as landscapes become more urban, reducing and fragmenting habitat for wildlife and bringing them closer to people. In the Western United States, elk and human populations are both growing, leading to increased rates of human-elk conflict. This study took place in Evergreen, CO, where Dedisse Park experiences high levels of human activity and elk presence. We aimed to determine where conflict is most prevalent and to determine which environmental and behavioral factors contribute to human-elk conflict. We found that conflict occurs primarily along the north side of the lake and that people and elk are …