Digital Commons Network^™

Heterotypic Interaction Of Α-Synuclein And Tdp-43 In Neurodegenerative Diseases, Shailendra Dhakal

Dissertations

Amyloid aggregates of specific proteins form important pathological hallmarks in many neurodegenerative diseases, defining neuronal degeneration and disease onset. Recently, increasing numbers of patients show co-morbidities and exhibit clinical and pathological overlaps between multiple neurodegenerative diseases including α-synucleinopathies and TDP-43 proteinopathies. These overlaps are often accompanied by co-localization of α-synuclein (αS) and TDP-43 enhancing the possibility of direct interactions to generate heterotypic amyloids with distinct cellular consequences. To understand this, we investigate the interaction of α-synuclein (αS) and prion-like domain of TDP-43 (TDP-43 PrLD) in both homogenous and inhomogeneous phases. Firstly, we show that monomeric TDP-43 PrLD and αS interact …

Teachers' And Administrators' Opinions Of Lgbtq Students And Inclusive Education, Katie Vining

Dissertations

The goal of this study was to explore opinions of teachers and administrators in the South, when dealing with inclusive education within their school. Additionally, the goal was to examine the reported effect of teachers and administrators’ opinions of providing LGBTQ students with inclusive education on the school climate and risk factors of students. The study explored what practices and strategies have been implemented to provide an inclusive education for LGBTQ students.

The results of this study confirmed that bullying of LGBTQ students exists in schools in Alabama, Louisiana, and Mississippi, and a lack of specific policy to address the …

Reiterating Visibility: Canadian Librarians’ Experiences Of Racial Microaggressions Via Findings From A Minority Librarians Network Redux Survey, Yanli Li, Maha Kumaran, Allan Cho, Valentina Ly, Suzanne Fernando, Michael David Miller

Library Publications

Based on the data from the Visible Minority Librarians of Canada 2021 Redux Survey, this study examines experiences of racial microaggressions among visible minority librarians in Canada. This research fills the gap in the library and information science (LIS) literature regarding racial microaggressions in librarianship in the Canadian context. Of the 148 respondents, 69% (n=102) experienced at least one stated racial microaggression. The result of a Kruskal-Wallis H test revealed a significant association between years of experience as a librarian and a librarian’s overall experiences with microaggressions. A post hoc test based on Bonferroni correction was run, which indicated that …

Sodium-Glucose Cotransporter 2 Inhibitor (Sglt2-I) In The Prevention Of Diabetic Kidney Disease Progression, And Its Role As An Antihypertensive Agent In The African American Population, Aran Michael G. Manalang, Justin Gambini

Doctor of Medical Science (DMSc)

Introduction:

Needs Assessment:

Originally used as antidiabetic medications, later clinical trial data showed beneficial effects in reducing the onset and progression of renal complications in people with and without diabetes. 13 Randomized clinical trials and ‘real world’ observational studies involving mostly type 2 diabetes patients showed that SGLT2-i can slow the decline in glomerular filtration rate (GFR), and reduce the onset of microalbuminuria and slow or even reverse the progression of proteinuria.13 Additionally, with diabetes being one of the many chronic conditions still primarily managed by primary care providers (PCP), it falls upon these professionals to have the knowledge and …

Curriculum Subcommittee Minutes December 7, 2023, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews:
• College of Agriculture and Applied Sciences
• Caine College of the Arts
• Jon M. Huntsman School of Business
• Emma Eccles Jones College of Education and Human Services
• College of Engineering
• College of Humanities and Social Sciences
• S.J. & Jessie E. Quinney College of Natural Resources
• College of Science
• College of Veterinary Medicine
• Other Business
• Adjourn: 3:02 pm

Intelpvt And Opt-Stvit: Advances In Vision Transformers For Object Detection, Classification And Video Recognition, Divya Nimma

Dissertations

Since the advent of Transformers, followed by Vision Transformers (ViTs), great success has been achieved by researchers in the field of computer vision and object detection. The difficult mechanism of splitting images into fixed patches posed a serious challenge in this arena and resulted in the loss of useful information at the time of object detection and classification. We propose an innovative Intelligent-based patching mechanism to overcome the challenges and integrate it seamlessly into the conventional Patch-based ViT framework. The proposed method enables the utilization of patches with flexible sizes to capture and retain essential semantic content from input images, …

2023 Fall Engr333 Section B Final Report, Ally Gauss, Stuart Johnston, Zachary Rozendal, Nora Terbeek, Samantha Bush, Daniel Cordeiro, David Harris, Nathan Zylstra, Mikayla Bindon, David Schmurr, Zachary Swart, Micah Vandeburg, David Conhoff, Mitchell Cook, Yonggi Kim, Mark Schultz

ENGR 333

Calvin University is currently committed to being carbon neutral by 2057. However, by 2057 the earth will see irreversible damage due to global warming. Because of the constant rise in global carbon emissions, President Boer tasked the students of ENGR-333 to find an earlier date for Calvin to become carbon neutral. Carbon net neutrality involves eliminating the emissions associated with heating and electricity. To have the most immediate impact, it was desired to reduce the most carbon as fast as was cost effective. Starting immediately, Calvin would start buying carbon free electricity from Consumer’s Energy, continuing until 2040 when Consumer’s …

Patrick Lavecchia V. Christian Fleming

2023 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. Clifton Shields

2023 Decisions

USDC for the Middle District of Pennsylvania

Florence Kocher V. Secretary Us Dept Of Veterans Affairs

2023 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. Michael Goldner

2023 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. Joseph Vezo

2023 Decisions

USDC for the Middle District of Pennsylvania

Joy Beatty V. Commissioner Social Security

2023 Decisions

USDC for the Western District of Pennsylvania

Javier Artache V. Superintendent Forest Sci

2023 Decisions

USDC for the Eastern District of Pennsylvania

Surgical Fire Prevention And Management: An Objective Structured Clinical Examination For Nurse Anesthesia, Tate Fazio, Kaleb Killens

Doctoral Projects

Sentinel events in health care are rare events, often corresponding with permanent injury or death. Fires in the operating room (OR) are one type of sentinel event. Although rare due to possible life-threatening injuries to patients and staff, appropriate surgical fire education is critical in nurse anesthesia education, as anesthesia providers play a significant role in surgical fires (Wunder et al., 2020). The development of simulation exercises has the potential for students to experience and become competent in managing high-acuity, low-frequency events, such as surgical fires (Wunder et al., 2020). The Nurse Anesthesia Program (NAP) at The University of Southern …

Defendant St. Isidore Of Seville Catholic Virtual School's Reply Brief In Support Of Motion To Dismiss, Michael H. Mcginley, Steven A. Engel, M. Scott Proctor, John A. Meiser, Michael R. Perri, Socorro Adams Dooley

Court Briefs

No. CV-2023-1857
OKPLAC, Inc. v. Statewide Virtual Charter School Board

From the Introduction

Plaintiffs' opposition to the motions to dismiss distills their challenge to the State's approval of St. Isidore of Seville Catholic Virtual School ("St. Isidore") to its essence: Plaintiffs believe that the State of Oklahoma may never allow a religious organization to operate a charter school because (they contend) any faith-based school would violate the Charter Schools Act and the Oklahoma Constitution. They purport to raise other, purely technical errors in the Board's decision to partner with St. Isidore; they baselessly speculate about ways in which they predict …

Spective, Andrew C. Smith

Game Design

Video Game, Andrew Smith, Puzzle Action game. Made for Fall 2023 Game Prototype class. In this game, the player must rotate the camera in order to obtain a new perspective and gain more visual information about the layout of the stage in order to avoid enemies, collect objects, and navigate and platform properly, in order to reach the end.

Exploring Perinatal Mental Health: Navigating Challenges And Support For Women Of Color, Chloey R. Pestorious

Counselor Education Capstones

This Capstone Project focuses on peripartum depression, particularly its implications for women of color during the perinatal period, which includes pregnancy, childbirth, and the postpartum period. Peripartum depression is a mental health condition that effects women, their families, and society as a whole (World Health Organization, 2008). The literature review takes a comprehensive approach, starting with an exploration of peripartum depression, including its prevalence, manifestations, and associated risk factors. Notably, women of color face a higher prevalence of peripartum depression, with disparities arising from multifaceted factors, including racial and ethnic healthcare disparities, socioeconomic challenges, and cultural nuances (Kozhimannil et al., …

Steven Voneida V. John Johnson

2023 Decisions

USDC for the Middle District of Pennsylvania

Giovanni Lepore V. Selectquote Insurance Services Inc

2023 Decisions

USDC for the District of New Jersey

2023 Fall Engr333 Section A Final Report, Owen Kalsbeek, Panashe Makuvaro, Luke Penning, Caleb Gaffner, David Visser, Jared Skaggs, Stephen Langerak, Kyle Borror, Caleb Clark, Michael Lanning, Brayden Raches, Sam Mennega, Seth Devries, Kyle Vandusen, Hayden White

ENGR 333

On 6 December 2017, then-president Michael Le Roy signed the President’s Climate Commitment, which committed Calvin University to carbon neutrality by 2057. Within a global scope, humanity has already emitted approximately 83% of its carbon allowance before causing global warming of 1.5°C. The Paris Climate Accords stated this temperature increase as the point at which humanity’s damage to the planet becomes irreversible. Given this, the year 2057 seemed like a dangerously late date for Calvin to achieve carbon neutrality. These concerns led President Boer to task the students of Engineering 333 with the following question: what earlier year should Calvin …

Educational Policies Committee Minutes December 7, 2023, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports:
• Curriculum Subcommittee
• Academic Standards Subcommittee
• General Education Subcommittee
• Other Business
• Adjourn: 4:00 pm

An Analysis Of The Effects Of Visual Art And Gender On Secondary Students’ Achievement In Geometry, Johnny Gary Iii

Dissertations

Students’ understanding of geometry can be hampered in part because of their inability to visualize, describe, draw, and recognize images and shapes. What if art and making could support students’ mathematics learning and interest and help them over the geometry hurdle? This work investigated visual-arts integrated geometry lessons to explore its impact on high school students’ understanding and attitudes. This study used a quasi-experimental mixed methods design, with a pre- and post- survey and interview data collected from geometry students at Mississippi high school. The control group was taught the same geometry content using a traditional curriculum, and the treatment …

Lack Of Quality Media Representation For Transgender Women, Seth Ririe

FHSS Mentored Research Conference

“Transgender” is a term used to describe people whose gender identity is incongruent with their sex assigned at birth. This brief discusses transgender women (that is, transgender people whose gender identity is female) and their experiences with popular narrative media representation. Transgender women are improperly or under-represented due to a lack of transgender media creators, the American public opinion of transgender women, and audience fragmentation, which keeps media featuring transgender women away from wider audiences. As a result of the lack of quality media representation for transgender women, stereotypes surrounding transgender women become more prevalent and transgender women may experience …

The Bison, December 7, 2023

The Bison Newspapers

No abstract provided.

Student Chamber Ensembles Recital, Arkansas State University Department Of Music

Performance Programs

No abstract provided.

Cobalt Chromium In Biomedical Applications And The Development Of A Pspp Map, Nouralhouda Jamal

BCoE Publications

During the world wars, Cobalt-Chromium (Co-Cr) alloys gained prominence for their use in aircraft engine components, where they exhibited high temperature strength and durability. They are used in a wide range of industries due to their unique set of qualities, particularly strength, corrosion resistance, and biocompatibility. They have emerged as versatile materials with a broad spectrum of applications, from aerospace and automotive components to biomedical implants.

This paper presents a thorough analysis of its composition, processing techniques, microstructure, mechanical properties, and performance characteristics. The primary goal of this project is to develop a PSPP (Process, structure, properties, and performance) map …

The Role Of Linguistics In Education, Laiba Zia

Publications and Research

This research aims to uncover the critical nuances that shape global learning experiences by delving into multifaceted dynamics of linguistics in education. This investigation includes the analysis of language barriers, preservation efforts, policy challenges and organizational obstacles, illuminating the complex relationship between language and education. A fundamental question guiding this inquiry is how linguistics fundamentally shapes educational landscapes, focusing on understanding the diverse ways language impacts different aspects of education. Using a thorough approach with articles, surveys, and case studies, this research gathers insights from different sources. It delves into the perspectives of final-year medical students, recognizes the role of …

December 7, 2023, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Kenyon Collegian - December 7, 2023

The Kenyon Collegian

No abstract provided.