Digital Commons Network^™

Cut Flower Markets And Marketing In The Intermountain West, Makylie Langford, Kynda R. Curtis, Melanie Stock

All Current Publications

This fact sheet discusses different markets for cut flowers in the Intermountain West, including wholesale and direct-to-consumer markets. Farmers markets, community-supported agriculture and subscription services, u-pick operations, farm venues, and online options are explored, as well as using social media to advertise and build clientele.

Timigp: An R Package To Depict The Tumor Microenvironment From Bulk Transcriptomics, Chenyang Li, Jianjun Zhang, Chao Cheng

Faculty, Staff and Students Publications

Exploring the clinical relevance of diverse immune cell types within the tumor microenvironment is pivotal for unraveling cancer intricacies and developing treatments. Here, we present a protocol for using tumor immune microenvironment illustration based on gene pairs, an R package to deduce cell-cell interactions, unveiling the association between immune cell relative abundance and patient prognoses from bulk gene expression and survival data. We describe steps for harnessing cell-type markers derived from single-cell RNA sequencing data to map the tumor immune microenvironment across a spectrum of cancer types. For complete details on the use and execution of this protocol, please refer …

Dermal Suture Height Differential: The Secret To Simplifying And Optimizing Wound Edge Eversion, Charles Dunn, Cyndi Yag-Howard, Rajiv Nathoo, Alexander Dane, Adam Leavitt, Adam Sutton, Ashley Wysong

GME Publications

No abstract provided.

T1 And Flair Signal Intensities Are Related To Tau Pathology In Dominantly Inherited Alzheimer Disease, Farzaneh Rahmani, Matthew R Brier, Brian A Gordon, Nicole Mckay, Shaney Flores, Sarah Keefe, Russ Hornbeck, Beau Ances, Nelly Joseph-Mathurin, Chengjie Xiong, Guoqiao Wang, Cyrus A Raji, Jorge J Libre-Guerra, Richard J Perrin, Eric Mcdade, Alisha Daniels, Celeste Karch, John C Morris, Randall J Bateman, Tammie L S Benzinger, Et Al.

2020-Current year OA Pubs

Carriers of mutations responsible for dominantly inherited Alzheimer disease provide a unique opportunity to study potential imaging biomarkers. Biomarkers based on routinely acquired clinical MR images, could supplement the extant invasive or logistically challenging) biomarker studies. We used 1104 longitudinal MR, 324 amyloid beta, and 87 tau positron emission tomography imaging sessions from 525 participants enrolled in the Dominantly Inherited Alzheimer Network Observational Study to extract novel imaging metrics representing the mean (μ) and standard deviation (σ) of standardized image intensities of T1-weighted and Fluid attenuated inversion recovery (FLAIR) MR scans. There was an exponential decrease in FLAIR-μ in mutation …

Combining The Tyrosine Kinase Inhibitor Cabozantinib And The Mtorc1/2 Inhibitor Sapanisertib Blocks Erk Pathway Activity And Suppresses Tumor Growth In Renal Cell Carcinoma, Yige Wu, Siqi Chen, Xiaolu Yang, Kazuhito Sato, Preet Lal, Andrew T Shinkle, Michael C Wendl, Tina M Primeau, Yanyan Zhao, Alanna Gould, Hua Sun, Jacqueline L Mudd, Jeremy Hoog, R Jay Mashl, Matthew A Wyczalkowski, Chia-Kuei Mo, Ruiyang Liu, John M Herndon, Sherri R Davies, Di Liu, Xi Ding, Ramaswamy Govindan, Shunqiang Li, James Hsieh, Ryan C Fields, Kian-Huat Lim, Cynthia X Ma, Li Ding, Feng Chen, Et Al.

2020-Current year OA Pubs

UNLABELLED: Current treatment approaches for renal cell carcinoma (RCC) face challenges in achieving durable tumor responses due to tumor heterogeneity and drug resistance. Combination therapies that leverage tumor molecular profiles could offer an avenue for enhancing treatment efficacy and addressing the limitations of current therapies. To identify effective strategies for treating RCC, we selected ten drugs guided by tumor biology to test in six RCC patient-derived xenograft (PDX) models. The multitargeted tyrosine kinase inhibitor (TKI) cabozantinib and mTORC1/2 inhibitor sapanisertib emerged as the most effective drugs, particularly when combined. The combination demonstrated favorable tolerability and inhibited tumor growth or induced …

Host-Microbiome Interactions In Distinct Subsets Of Preterm Labor And Birth, Jose Galaz, Roberto Romero, Jonathan M Greenberg, Kevin R Theis, Marcia Arenas-Hernandez, Yi Xu, Marcelo Farias-Jofre, Derek Miller, Tomi Kanninen, Valeria Garcia-Flores, Nardhy Gomez-Lopez

2020-Current year OA Pubs

Preterm birth, the leading cause of perinatal morbidity, often follows premature labor, a syndrome whose prevention remains a challenge. To better understand the relationship between premature labor and host-microbiome interactions, we conducted a mechanistic investigation using three preterm birth models. We report that intra-amniotic delivery of LPS triggers inflammatory responses in the amniotic cavity and cervico-vaginal microenvironment, causing vaginal microbiome changes and signs of active labor. Intra-amniotic IL-1α delivery causes a moderate inflammatory response in the amniotic cavity but increasing inflammation in the cervico-vaginal space, leading to vaginal microbiome disruption and signs of active labor. Conversely, progesterone action blockade by …

Screening For Uterine Fibroids In Black Women, Winnie N. Kagendo

Doctor of Nursing Practice (DNP) Projects

Background: Uterine fibroids are benign growths in the uterine muscle that affect around 70% of women. Black women have a higher risk, with three times the likelihood of developing fibroids compared to other races.

Problem: The issue of uterine fibroids continues to be poorly addressed in healthcare settings. Black women continue to be particularly adversely impacted by this problem. There is a lack of better screening methods, leading to late detection and limited treatment options for those hoping to maintain fertility.

Methods: A quality improvement project was implemented at a primary care clinic in Loma Linda, California, using the Uterine …

Enhancing Mental Health Assessments For Hysterectomy Patients: Implementing A Depression Screening Tool For Healthcare Clinicians, Dede Mihedji

Doctor of Nursing Practice (DNP) Projects

Background: Hysterectomies are prevalent in the United States ranging from

5.1 to 5.8 per 1000 women (Harnod et al., 2018). A standardized screening tool for assessing preoperative depression could mitigate the worsening of postoperative depressive symptoms in patients scheduled for a hysterectomy. Local Problem: Currently, there is no standard practice for preoperative depression screening in hysterectomy patients. Studies have identified that a hysterectomy may increase the risk of cardiovascular events, menopause, depression, and other outcomes (Madueke-Laveaux et al., 2022). Methods: To address the gap, clinicians attended a fifteen-minute Zoom course on the Patient Health Questionnaire 9 (PHQ-9) and its …

Whitworth College, Brookhaven, Mississippi

Pine Belt Region

This postcard features a color image of the famous entry gate of Whitworth Female College at corner of W. Cherokee Street and Jackson Street, near where Mary Jane Lampson Auditorium would be built in 1912. A gated, white arch with "Whitworth College" lettered on it, stands in front of a long white walkway. A large building is a the ended of the walkway. Trees line the road to the left of the arch. Whitworth Female College was a Methodist women’s college in Brookhaven, Mississippi, founded in 1858 by Milton Whitworth. It operated until 1938 when it was merged with Millsaps …

West Pine Street, Hattiesburg, Mississippi

Pine Belt Region

This postcard features a color illustration of West Pine Street in Hattiesburg, Mississippi. The street is split by a grassy median. A large white house is seen on the right and what appears to be a church is on the left. Trees and sidewalks line both sides of the street. Ring shaped clouds are in the sky. The title of the card is printed along the bottom left edge of the card.

Mrs. R. B. Campbell Residence, Columbia, Mississippi

Pine Belt Region

This postcard features a sepia toned image of a white, clapboard house with a long front porch, and two dormers on the hip style roof. A chicken wire fence is in front of the house and a chicken can be seen to the left in the yard of the house. A utility pole is directly in front of the house at the sidewalk and trees are seen on the sides, back, and front of the house. "Mrs. R. B. Campbell, [box number] Columbia, Miss." is written on the back of the card.

Mcleod Furniture Co., Laurel, Mississippi

Pine Belt Region

This postcard features the McLeod Furniture Company in Laurel, Mississippi, a long building with a wall of windows. A pile of wood is in the foreground and railroad tracks run in front of the building and a train car is sitting at the far end. A water tower is seen in the distance. The title of the card is printed in the upper right of the card.

Pontiac Eastern Corp. Oil Refinery, Purvis, Mississippi

Pine Belt Region

This postcard features a color image of the machinery among trees at the Pontiac Eastern Corp. Oil Refinery in Purvis, Mississippi.

Masonic Temple, Hattiesburg, Mississippi

Pine Belt Region

This postcard features a color illustration of the Masonic Temple in Hattiesburg, Mississippi, a two story colonial style building with two story pillar columns flanking the entrance, an arched, stained glass window above the front entrance, and hedges surrounding the exterior. "Masonic Temple" is lettered between the gabled roof and the trim of the above the second story. A large tree is on the left corner of the yard and cars are parked at the sidewalk to the left. The title of the card is printed along the bottom edge of the image.

Main Street, Mount Olive, Mississippi

Pine Belt Region

This postcard features a black and white image of the buildings on Min Street in Mount Olive, Mississippi. The corner building on the left has a sign for Calhoun Drug Co. at the roofline. Utility poles line the street on either side. The title of the card is printed beneath the bottom edge of the image.

Logging Scene Near Laurel, Mississippi

Pine Belt Region

This postcard features a black and white image of a wagon of logs hitched to a heard of oxen with trees and utility poles behind them. A man is seen at the head of the oxen.

Lamar County Courthouse, Purvis, Mississippi

Pine Belt Region

This postcard features a black and white image o the Lamar County Courthouse in Purvis, Mississippi, a two story building with a two pillar columns at the entrance and white trim. Unreadable signs are on the lawn in front and a mid-twentieth century car is parked at the sidewalk. The identity and location of the image is written in pen on the back of the card.

Inez Hotel, Brookhaven, Mississippi

Pine Belt Region

This postcard features a color image of the Inez Hotel in Brookhaven, Mississippi, a long, three story building with a second story balcony and arched windows. A tree is on the left end in front of the hotel. The title of the card is printed in red along the bottom left of the card and the publisher is printed in the lower right edge of the card.

Inez Hotel, Brookhaven, Mississippi

Pine Belt Region

This postcard features a black and white image of the Inez Hotel in Brookhaven, Mississippi, a long, three story building with a second story balcony and arched windows. A tree is on the left end in front of the hotel. The title of the card is printed in red along the bottom left of the card and the publisher is printed in the lower right edge of the card.

The Hotel Hattiesburg, Hattiesburg, Mississippi

Pine Belt Region

This postcard features a black and white image of a corner street view of the Hotel Hattiesburg in Hattiesburg, Mississippi, a five story brick hotel building with white moldings. The hotel is divided into to tall sections separated by a two story ornate main entrance. The title of the card is printed along the upper right edge of the card. An inscription is written in the white edge on the right of the card and on the left half on the back of the card. [see transcription field] The back of the card is addressed to Lula K. Wright in …

Front Street, Waynesboro, Mississippi

Pine Belt Region

This postcard features a black and white image of Front Street in Waynesboro, Mississippi, with views of the commercial buildings, trees, and utility poles. The tile of the card is printed in red along the upper edge of the image. The back of the card is addressed to Mrs. A. L. Wilkins in Silver Springs, Maryland the card was not mailed. An inscription is written in blue ink on the left half of the card. [see transcription field]

First National Bank Building, Lumberton, Mississippi

Pine Belt Region

This postcard features a black and white image of the First National Bank Building in Lumberton, Mississippi, a two story brick building with arched molding detail above some of the windows and dental molding along the top of the second story. Liverpool, London, and Globe Insurance Co. is written on the side. In the right corner is the local drug store, with a dog in the doorway, and a Coca-Cola ad in the window. Ca. 1905 Utility poles are on the corner in front and back. The title of the card is printed along the bottom edge of the card.

Front Street, Waynesboro, Mississippi

Pine Belt Region

This postcard features a black and white image of Front Street in Waynesboro, Mississippi, with views of the commercial buildings and utility poles as well as a gazebo. The image is in the upper left corner of the card and the title of the card is printed beneath the bottom edge of the image.

First Baptist Church, Purvis, Mississippi

Pine Belt Region

This postcard features a color photograph of the First Baptist Church in Purvis, Mississippi, a one story, red brick building with four pillar columns across the front porch entrance and a bell tower with a steeple on top. The windows on the side of the church are arched. Trees are to the side and behind the church and a small sign for the church is to the right at the sidewalk. The name and location of the church are printed in the upper left corner on the back of the card.

First Baptist Church, Brookhaven, Mississippi

Pine Belt Region

This postcard features the First Baptist Church in Brookhaven, Mississippi, a three story, red brick, building with two, two story pillar columns on either side of the entrance. Stained glass windows are on the top two floors and a three domes are on the roof. Trees are on the side and front of the church. The title of the card is printed along the upper right edge of the image.

Corner Oak And Magnolia Streets, Laurel, Mississippi

Pine Belt Region

This postcard features a color image of the building on the corner of Oak Street and Magnolia Street. The building has a cupola on the corner and yellow "Laurel Light and Railway Company" street cars are parked in front. A man in a dark suit and bowler hat is standing in the street near the lead street car.

Sanford A. French Family, Hattiesburg, Mississippi

Pine Belt Region

This postcard features a black and white portrait of the S. A. French Family in Hattiesburg, Mississippi Ca. 1908. Sanford A. French (Sept. 3, 1845-April 18, 1917), a Virginian-born engineer and grocer is pictured with his Kentucky-born wife Harriette “Hattie” E. Hickman French (Oct. 16, 1863-March 9, 1932). Their daughter, Gay is pictured behind Harriette and the two women at the back are unidentified. All the women are wearing white dresses and French is wearing a bowler hat with a suit and bowtie. The group is standing in front of a porch with flowers and plants in front of them. …

Baseball Park, Hattiesburg, Mississippi

Pine Belt Region

This postcard features a color illustration of a crowd gathered in the Hattiesburg, Mississippi baseball park watching a baseball game. Houses are seen beyond the baseball field. The title of the card is printed in the upper left of the image.

Commercial Avenue Looking East, Laurel, Mississippi

Pine Belt Region

This postcard features a color illustration of Commercial Avenue looking east in Laurel, Mississippi. Buildings of various sizes and styles on either side of the street along with horse drawn wagons. The title of the card is printed in red in the upper edge of the image.

Two Men With Four Fish On A Pole

Pine Belt Region

This black and white photograph features two men standing in front of a hedge with a long pole braced on their shoulders with four fish hanging from the pole. The man on the right is wearing a newsboy cap and dark overalls over a dark shirt and is holding one hand up and pointing toward the sky. The man on the left is wearing a fedora, a white stripped shirt and dark trousers with dark suspenders. A large tree is to the left behind the hedge. The donor indicated that the series of fish/fishing photographs were taken in Hattiesburg and …