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2023

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Identifying Tethering Proteins Important For Mitochondria-Actin Interactions, Tejas Purimetla Jan 2023

Identifying Tethering Proteins Important For Mitochondria-Actin Interactions, Tejas Purimetla

Harriet L Wilkes Honors College Theses 2020 - Present

The brain consumes 20% of the total energy of the human body despite its 2% volume, and deficiencies in its energy supplies lead to brain disorders. Understanding how neurons meet their high energy demands, especially during synaptic plasticity, may help solve these challenging brain conditions. Prior research shows that mitochondria exist as stabilized compartments within dendrites, and this stabilization is accomplished via tethering to the cytoskeleton. This mitochondria–cytoskeleton tethering is likely achieved by proteins, but the specific proteins involved remain unclear. This project will determine the protein mechanisms tethering and stabilizing mitochondria in regions of high energy demand. We hypothesize …

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Effect Of Salt On The Conduction Of Electricity In Gels, Joshua Sanderson Jan 2023

Effect Of Salt On The Conduction Of Electricity In Gels, Joshua Sanderson

Harriet L Wilkes Honors College Theses 2020 - Present

While robotics have been widely incorporated into the agricultural industry, the burgeoning sector of aquaculture has only recently seen the application of these progressive technologies. One of the most important parameters to aquaculture facilities is the concentration of dissolved oxygen in the ponds as it is directly correlated to stock health. The labs of Bing Ouyang and Paul Wils at Harbor Branch Oceanographic Institute have combined the technological aspects already seen in agriculture and this essential water quality parameter to create an autonomous monitoring system captained by drones. In this thesis, I examine a method to optimize the part of …

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Reversal Of Sex And Age-Dependent Social Deficits In Dat Val559 Mice, Steven L. Shatkhin Jan 2023

Reversal Of Sex And Age-Dependent Social Deficits In Dat Val559 Mice, Steven L. Shatkhin

Harriet L Wilkes Honors College Theses 2020 - Present

Dopaminergic dysfunction has been implicated in various neuropsychiatric disorders including autism spectrum disorder (ASD). The dopamine transporter (DAT) is responsible for the reuptake of synaptic dopamine and critical dopaminergic signaling. The DAT Val550 mutation, a mutation identified in two boys with ASD, drives an aberrant dopamine efflux into the synaptic cleft and leads to alterations in dopamine homeostasis in DAT Val559 mice. Previous research found that DAT Val559 mice display unique patterns of social behavior that are dependent on sex. Here we explore the effects that sex and age have on sociability and look at the level of differential effect …

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Is Adhd Directly Related To Eventual Participation In Criminal Behavior, Tayler Vinciguerra Jan 2023

Is Adhd Directly Related To Eventual Participation In Criminal Behavior, Tayler Vinciguerra

Harriet L Wilkes Honors College Theses 2020 - Present

Attention Deficit Hyperactivity Disorder (ADHD) is among one of the most thoroughly studied disorders in psychological and neurological fields that examine psychopathology, along with being one of the most common as well. It is known to have symptomatic features that may have a relationship, in some way, to outcomes that are linked to criminal behaviors. However, due to the disorder’s various facets, comorbidities, and unique environmental interactions, this relationship between ADHD and criminality is a rather complex and psychologically difficult one to ascertain. A number of peer-reviewed studied were analyzed and integrated in this literary review in order to explore …

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Morphologies Of Active Galactic Nuclei Host Galaxies Observed In Mid-Infrared Wavelengths, Olga St-Onge Jan 2023

Morphologies Of Active Galactic Nuclei Host Galaxies Observed In Mid-Infrared Wavelengths, Olga St-Onge

Harriet L Wilkes Honors College Theses 2020 - Present

Active Galactic Nuclei (AGN) are structures found in some galaxies where the central supermassive black hole accretes material from the surrounding galaxy. Galaxy mergers are the predominant theory for what triggers black hole accretion. The hypothesis tested in this study is that AGN with distorted morphologies, indicating a recent merger, would be obscured by surrounding dust. To study this, the morphologies and colors of mid-infrared (MIR) variability-selected AGN in five extragalactic fields imaged by the Hubble Space Telescope were studied. First, it was determined which galaxies were obscured by dust by examining their optical-to-MIR color indices using photometry in the …

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Two Parmotrema Lichen Species As Pollution Bioindicators In Florida, Hunter Womble Jan 2023

Two Parmotrema Lichen Species As Pollution Bioindicators In Florida, Hunter Womble

Harriet L Wilkes Honors College Theses 2020 - Present

Lichens are commonly used as bioindicators of air pollution. For my thesis, I tested the utility of two easily identified lichen species as bioindicators. Parmotrema perforatum is considered to be pollution intolerant, while Parmotrema subrigidium is considered to be somewhat pollution tolerant. I surveyed P. perforatum and P. subrigidum growing on the trunks of southern live oak trees (Quercus virginiana) at two sites on the John D. MacArthur campus of Florida Atlantic University in Jupiter, Florida that differed in exposure to road traffic. One site on the interior of campus (AOS1) was distant from any road, while the other site …

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Computer Vision: A Pair Of Fresh Eyes To Study Animal Behavior, Warren Yee Jan 2023

Computer Vision: A Pair Of Fresh Eyes To Study Animal Behavior, Warren Yee

Harriet L Wilkes Honors College Theses 2020 - Present

Computer vision has completely changed the way we study animal behavior. Over the past 15 years, researchers have developed several computer vision-based tools to automatically track an animal’s position and pose through time. This data can then be used to uncover the reasons behind the animal’s behavior. In this talk, I will compare two tracking tools, one based on contrast detection (Trilab-Tracker), and one based on machine learning (DeepLabCut), to determine which performs better on an existing set of videos of Mexican cavefish (Astyanax mexicanus) collected in Johanna Kowalko’s lab.

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The Evolutionary Basis Of Sensory-Motor Integration Through Crispr/Cas9, Samantha Zaninelli Jan 2023

The Evolutionary Basis Of Sensory-Motor Integration Through Crispr/Cas9, Samantha Zaninelli

Harriet L Wilkes Honors College Theses 2020 - Present

Startle responses are evolutionarily conserved behaviors that play key roles in the daily necessities of an animal, including foraging and predator avoidance. While the neuronal mechanisms underlying startle responses are well understood, less is known about the evolutionary mechanisms that modify this behavior. This study places a focus on uncovering the evolutionary and genetic basis of sensory-motor integration through the analysis of startle response behavior. We address this question using the emerging evolutionary model, Astyanax mexicanus, which consists of 2 different populations: a river-dwelling surface fish and a cave-dwelling fish. These populations drastically evolved differential traits due to their environment. …

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Coastal Absences In Andean Archaeology And The Construction Of A Highland-Centric Indigeneity, Ben Crawford Jan 2023

Coastal Absences In Andean Archaeology And The Construction Of A Highland-Centric Indigeneity, Ben Crawford

Harriet L Wilkes Honors College Theses 2020 - Present

As a tangible linkage to the past, archaeological material culture plays a vital role in constructing contemporary identities. In Ecuador, archaeology focused on the state societies of the Andean highlands has long informed a hill-centric national narrative about the indigenous past, leaving coastal peoples on the margins. Conversely, more recent efforts at investigating overlooked coastal sites have paralleled the process of coastal communities publically reclaiming their indigenous status. This thesis investigates the historical trends in the field of Andean archaeology which have contributed to a popular conception of highland indigeneity in Ecuador that excludes coastal peoples. However, coastal peoples’ recent …

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Exploring Fractals: The Madelbrot Set, Sarah Diehl Jan 2023

Exploring Fractals: The Madelbrot Set, Sarah Diehl

Harriet L Wilkes Honors College Theses 2020 - Present

A fractal is a shape that is self-similar through infinitely many iterations. There are many instances of self-similarity in nature, but fractals can be computer-generated and even modeled after nature. One of the most notable examples of a computergenerated fractal is the Mandelbrot set, which is defined as the set of those z for which the orbit of fc(z) = z2 + c is bounded. This set is an instance of how a simple iteration can be extremely intricate.

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Delineating The Intracellular And Extracellular Role Of Matrix Metalloproteinase 14 In Primary And Metastatic Pancreatic Cancers Bxpc-3 And Hpaf-Ii, Nihasika Gopi Jan 2023

Delineating The Intracellular And Extracellular Role Of Matrix Metalloproteinase 14 In Primary And Metastatic Pancreatic Cancers Bxpc-3 And Hpaf-Ii, Nihasika Gopi

Harriet L Wilkes Honors College Theses 2020 - Present

Using flow cytometry and two forms of hypoxic induction, chemical (CoCl2) and gaseous (Tri-gas chamber), this study highlighted the advantages of quantitative analyses of MMP-14 expression (intracellularly/extracellularly) for one primary (BxPC-3) and one metastatic (HPAF-II) pancreatic cancer line. No significant changes in MMP-14 expression were observed for pancreatic cancer lines using CoCl2. Increased expression levels of MMP-14 were observed using tri-gas incubation maintaining oxygen levels at 2% intracellularly for HPAF-II, but not BxPC-3. A combination of 2D/3D cell culturing techniques were also used to examine changes in cellular behavior/morphology after hypoxic exposure and a 24-hour reoxygenation cycle. BxPC-3 cells showed …

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Investigation Of Environmental And Genetic Factors On Circadian Rhythm And Longevity, Mia Lin Amato Jan 2023

Investigation Of Environmental And Genetic Factors On Circadian Rhythm And Longevity, Mia Lin Amato

Harriet L Wilkes Honors College Theses 2020 - Present

Studies of longevity and behavior have been facilitated by the genetically tractable model, Drosophila melanogaster (D. melanogaster). Disrupted circadian rhythms can be detrimental to health and lifespan by dysregulating the biological rhythms that guide behaviors such as sleeping and feeding. These stressors are associated with an increased risk for cancer and neurodegenerative diseases. Understanding how circadian biology is regulated by aging may inform novel interventions for age-related diseases. In this two-part study, we first characterize the lifespan of D. melanogaster under an extended light/dark cycle to determine whether dysregulated circadian rhythms affect longevity. The second study analyzes the effect of …

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The Reevaluation Of Punishment, Jonathan Alexander Barroso Jan 2023

The Reevaluation Of Punishment, Jonathan Alexander Barroso

Harriet L Wilkes Honors College Theses 2020 - Present

Kaplow and Shavell, two scholars of law and economics, defend the utilitarian approach to punishment. They try to find the most efficient way to deter crime using a mathematical formula. According to their efficiency formula, the ideal sanction is the expected utility of the crime divided by the probability of conviction. This calculation could be effective in deterring crime, but it often leads to disproportionate punishments. I argue that a retributivist approach is a better option for a society as it uses proportional punishment with an underlying principle of punishing for justice. Even in the United States, cruel and unusual …

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A Floral Survey Of The Abacoa Gopher Tortoise Preserve, Malaika Bates Jan 2023

A Floral Survey Of The Abacoa Gopher Tortoise Preserve, Malaika Bates

Harriet L Wilkes Honors College Theses 2020 - Present

The Abacoa Gopher Tortoise Preserve is a 60-ha section of the Abacoa Greenway (designated RangeⅠ) consisting of scrubby pine flatwood habitat. For this thesis, I used the iNaturalist app as a tool to identify and create a comprehensive list of all plant species in Range Ⅰ. I organized this information by IUCN conservation status to distinguish between invasive, native, and endemic species. I compare this list to similar floral surveys done in this preserve to obtain a view of how the composition of the preserve is changing over time. I used the initial conservation targets for the Abacoa Greenway to …

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‘They’Re Just Kids: The Case Against Adult Sentencing For Juvenile Offenders’, Renise Bleck Jan 2023

‘They’Re Just Kids: The Case Against Adult Sentencing For Juvenile Offenders’, Renise Bleck

Harriet L Wilkes Honors College Theses 2020 - Present

Nathaniel Brazill, when 13, fatally shot one of his schoolteachers. Brazill was tried as an adult and sentenced to 28 years in prison without the possibility of parole. Such harsh sentences for such young offenders seem drastic and unfair, therefore I argue that the juvenile justice system should take not a punitive but a rehabilitative approach to minors. I first discuss different theories of why society punishes and whether they apply to the way juveniles are punished today. Drawing on research in psychology, I detail key cognitive differences between minors and adults to argue that juveniles have no place in …

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Portrayals Of Autism Spectrum Disorder In Contemporary Fiction, Lara Boerth-Dryden Jan 2023

Portrayals Of Autism Spectrum Disorder In Contemporary Fiction, Lara Boerth-Dryden

Harriet L Wilkes Honors College Theses 2020 - Present

Literature is an integral medium through which individuals use language to create a shared experience with an audience. Writing as an act is an intimate expression of identity. So, what does it mean that there are some voices who are not equally represented and heard in literature? There is an interesting juxtaposition between literature and disabilities. Certain people with disabilities such as Autism Spectrum Disorder (ASD) struggle at communication, articulation, and interpretation. This paper seeks to analyze representations and portrayals of individuals with ASD in fiction, and compare differences in these representations based on whether the author has an ASD …

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Guilty But Insane?: The Case Of John Hinckley, Shanece Coppin Jan 2023

Guilty But Insane?: The Case Of John Hinckley, Shanece Coppin

Harriet L Wilkes Honors College Theses 2020 - Present

On March 30th, 1981, John Hinckley tried to assassinate President Ronald Reagan using a .22 caliber revolver. As a result, he wounded Reagan, Secret Service Agent Tim McCarthy, police officer Thomas Delahanty, and White House Press Secretary James Brady (who was left permanently disabled and died in 2014 from his gunshot injuries). Hinckley did so to grab the attention of Jodie Foster from the film Taxi Driver. Hinckley was found not guilty by reason of insanity and placed into psychiatric care. I argue that Hinkley should be found guilty but insane under the retributive theory of punishment. After discussing Hinckley’s …

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A New Labor Movement: What Motivates Workers To Unionize And What Stands In Their Way?, Dawid Digangi Jan 2023

A New Labor Movement: What Motivates Workers To Unionize And What Stands In Their Way?, Dawid Digangi

Harriet L Wilkes Honors College Theses 2020 - Present

Prior to the COVID-19 pandemic, union rates in the United States were at their lowest since the 1980s. The recent success of unionization efforts at companies such as Amazon and Starbucks raise questions about what makes unionization successful and which factors explain the current resurgence in labor organizing. This thesis explores theories about what drives workers to unionize, including feelings of dissatisfaction and estrangement (Marx), the gap between an employee's expectations and achievements (Wheeler), community and social movement solidarity, legal frameworks, and other factors. I conclude that the communication between workers and the resources of the movement are directly proportional …

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Floral Survey And Species Checklist Of Frenchman’S Forest, Jessica Elkins Jan 2023

Floral Survey And Species Checklist Of Frenchman’S Forest, Jessica Elkins

Harriet L Wilkes Honors College Theses 2020 - Present

Frenchman’s Forest Natural Area in Palm Beach Gardens, Florida, is a 172-acre (70-hectare) preserve that includes diverse ecosystems, including scrub flatwoods, pine flatwoods, wet flatwoods, and swamp. Earlier floral inventories of this site listed 477 plant species. For my thesis, I surveyed plants in Frenchman’s Forest and compiled a list of plant species documented in Frenchman’s Forest in 2022-2023 based on photographs posted to the iNaturalist website. I found that most of the plant species I documented, a total of 179 plant species, include 37 native and eight non-native species not previously listed. These eight non-native species are described further …

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A Survey Of Florida Bat Species Feeding At Highway Rest Areas, Ariel Fernandez Jan 2023

A Survey Of Florida Bat Species Feeding At Highway Rest Areas, Ariel Fernandez

Harriet L Wilkes Honors College Theses 2020 - Present

Florida is home to 13 species of bats, all of which are insectivorous. As humans immigrated into areas that were previously natural, bats have had to adjust their habits to live alongside us. Bats in Florida are commonly seen foraging for insects attracted to artificial lights. For my thesis, I set up ultrasonic recording equipment at highway rest areas under large streetlights in Martin and Palm Beach County to see how frequently different bat species visited each area. I identified a total of 1598 calls, including 159 calls of rare or endangered species. I found most frequently recorded species at …

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Design For Resilience And Wildfire Recovery, Kyla Danforth, Karina Rodgers, John Sandlin, Ayonitoluwa Oyenuga, Vidal Gonzales, Tina Ruiz, Helen Ganahl, Erin Callahan, Michaele Pride, Catherine Harris Jan 2023

Design For Resilience And Wildfire Recovery, Kyla Danforth, Karina Rodgers, John Sandlin, Ayonitoluwa Oyenuga, Vidal Gonzales, Tina Ruiz, Helen Ganahl, Erin Callahan, Michaele Pride, Catherine Harris

Design and Planning Assistance Center - Projects

This report reveals critical strategies for recovery and resiliency after the 2022 Hermit’s Peak / Calf Canyon Fire in Mora and San Miguel counties. The plan presents background information on population demographics, natural systems, fire management practices, and human history. It assesses the causes and impacts of the fire and associated flooding. In response, the authors offer recommendations to support housing, historic preservation, economic recovery, watershed health, infrastructure, and food systems that are more resilient and accessible.

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University Of New Mexico Health Sciences Center Discovery Research Annual Report 2023, Michael Haederle, Claire Hannon, Elizabeth Dwyer Sandlin, Nicole San Roman, Chris Ramirez, Brianna Wilson, Jett Loe, Sara Mota, Sarah Head Jan 2023

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2023, Michael Haederle, Claire Hannon, Elizabeth Dwyer Sandlin, Nicole San Roman, Chris Ramirez, Brianna Wilson, Jett Loe, Sara Mota, Sarah Head

Research Annual Reports

Research annual report from the University of New Mexico Health Sciences Center.

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Hslic Annual Report Fy2022-23, University Of New Mexico Health Sciences Library And Informatics Center Jan 2023

Hslic Annual Report Fy2022-23, University Of New Mexico Health Sciences Library And Informatics Center

HSLIC Annual Reports

No abstract provided.

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Harnessing Axonal Transport To Map Reward Circuitry: Differing Brain-Wide Projections From Medial Prefrontal Cortical Domains, Elaine L. Bearer, Christopher S. Medina, Taylor W. Uselman, Russell E. Jacobs Jan 2023

Harnessing Axonal Transport To Map Reward Circuitry: Differing Brain-Wide Projections From Medial Prefrontal Cortical Domains, Elaine L. Bearer, Christopher S. Medina, Taylor W. Uselman, Russell E. Jacobs

Pathology Research and Scholarship

Neurons project long axons that contact other distant neurons. Neurons in the medial prefrontal cortex project into the limbic system to regulate responses to reward or threat. Diminished neural activity in prefrontal cortex is associated with loss of executive function leading to drug use, yet the specific circuitry that mediate these effects is unknown. Different regions within the medial prefrontal cortex may project to differing limbic system nuclei. Here, we exploited the cell biology of intracellular membrane trafficking, fast axonal transport, to map projections from two adjacent medial prefrontal cortical regions. We used Mn(II), a calcium analog, to trace medial …

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Implementing Smart Factory: A Fuzzy-Set Analysis To Uncover Successful Paths, Hyunmi Jang, Mohamed Yacine Haddoud, Saeyeon Roh, Adah Kole Emmanuel Onjewu, Taeeun Choi Jan 2023

Implementing Smart Factory: A Fuzzy-Set Analysis To Uncover Successful Paths, Hyunmi Jang, Mohamed Yacine Haddoud, Saeyeon Roh, Adah Kole Emmanuel Onjewu, Taeeun Choi

Plymouth Business School

Despite the pervasiveness of the Fourth Industrial Revolution, few studies have examined the adoption of smart factories. Scholars have long examined firms' willingness to adopt smart factories. Thus, this study heeds this call by investigating the factors driving the adoption of smart factories. It employs a fuzzy-set configuration approach to capture the complex interactions underlying these drivers in the context of South Korean marine equipment firms. Based on data from a sample of 180 respondents, the findings revealed four complex paths with factors including government support, the entrepreneurial spirit of top management, efficiency expectation, and financial preparedness shaping the high …

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An Overview Of Plithogenic Set And Symbolic Plithogenic Algebraic Structures, Florentin Smarandache Jan 2023

An Overview Of Plithogenic Set And Symbolic Plithogenic Algebraic Structures, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This paper is devoted to Plithogeny, Plithogenic Set, and its extensions. These concepts are branches of uncertainty and indeterminacy instruments of practical and theoretical interest. Starting with some examples, we proceed towards general structures. Then we present definitions and applications of the principal concepts derived from plithogeny, and relate them to complex problems.

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New Types Of Soft Sets: Hypersoft Set, Indetermsoft Set, Indetermhypersoft Set, And Treesoft Set, Florentin Smarandache Jan 2023

New Types Of Soft Sets: Hypersoft Set, Indetermsoft Set, Indetermhypersoft Set, And Treesoft Set, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This is a review paper, where we recall the definitions together with practical applications of the Soft Set and its extensions to HyperSoft Set, IndetermSoft Set, IndetermHyperSoft Set, and TreeSoft Set.

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Nidus Idearum. Scilogs, Xii: Seed & Heed, Florentin Smarandache Jan 2023

Nidus Idearum. Scilogs, Xii: Seed & Heed, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this twelfth book of scilogs – called seed & heed –, one may find topics on Neutrosophy, Superluminal Physics, Mathematics, Information Fusion, Philosophy, or Sociology – email messages to research colleagues, or replies, notes, comments, remarks about authors, articles, or books, spontaneous ideas, and so on.

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Nidus Idearum. Scilogs, Xi: In-Turns And Out-Turns, Florentin Smarandache Jan 2023

Nidus Idearum. Scilogs, Xi: In-Turns And Out-Turns, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this eleventh book of scilogs – called in-turns and out-turns –, one may find new and old questions and solutions, referring mostly to topics on Neutrosophy, but also Multispace, with miscellaneous addition of topics on Physics, Mathematics, or Sociology – email messages to research colleagues, or replies, notes about authors, articles, or books, spontaneous ideas, and so on.

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Towards Soliton Computer Based On Solitary Wavesolution Of Maxwell-Dirac Equation / A Plausible Alternative To Manakov System, Victor Christianto, Florentin Smarandache Jan 2023

Towards Soliton Computer Based On Solitary Wavesolution Of Maxwell-Dirac Equation / A Plausible Alternative To Manakov System, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In recent years, there are a number of proposals to consider collision-based soliton computer based on certain chemical reactions, namely Belousov-Zhabotinsky reaction, which leads to soliton solutions of coupled Nonlinear Schroedinger equations. They arecalled Manakov System. But it seems to us that such a soliton computer model can also be based on solitary wave solution of Maxwell-Dirac equation, which reduces to Choquard equation. And soliton solution of Choquard equation has been investigated by many researchers, therefore it seems more profound from physics perspective. However, we consider both schemes of soliton computer are equally possible. More researches areneeded to verify our …

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