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2023

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Dnp Final Report: Vascular Access In Burn Patients: An Evidence-Based Practice Project, Amanda Venable Jan 2023

Dnp Final Report: Vascular Access In Burn Patients: An Evidence-Based Practice Project, Amanda Venable

DNP Final Reports

Vascular access in burn patients is a challenging aspect of care that affects the healthcare team and patients daily. The goal in this evidence-based practice project at a southern United States burn center was to improve the quality of the vascular access process by reducing the use of Central Venous Lines (CVL) and unsuccessful venipuncture attempts. The following practice question was formed: In hospitalized burn patients (P), how does a vascular access team with ultrasound-guided peripheral IV capability (I) compared with no vascular access team and standard IV insertion (C) affect central line days (O1) or patient experience (O2) during …

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Carbon-Based Polymer Composite For Electrochemical Sensing Of Creatinine Sodium Potassium And Calcium Ions, Kanyapat Teekayupak Jan 2023

Carbon-Based Polymer Composite For Electrochemical Sensing Of Creatinine Sodium Potassium And Calcium Ions, Kanyapat Teekayupak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Electrochemical sensors have emerged as indispensable tools for various applications including environmental monitoring, food safety, and biomedical diagnostics owing to their simplicity, sensitivity, and fast response. However, traditional methods for electrode fabrication are often associated with drawbacks such as cleanroom requirements, multi-step processes involving toxic materials, high waste consumption, and high costs. To address the limitations, this dissertation evaluates the utilization of 3D printing, laser engraving, and inkjet printing technologies for the fabrication of electrochemical sensors based on carbon-based polymer composites. In the first part, a 3D-printed electrochemical sensor based on a copper oxide nanoparticle-ionic liquid/reduced graphene oxide (CuO-IL/rGO) modified …

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Green Synthesis For Silver Nanoparticle /Natural Rubber/ Nanocellulose Bio-Polymeric Composites, Puttakhun Meemai Jan 2023

Green Synthesis For Silver Nanoparticle /Natural Rubber/ Nanocellulose Bio-Polymeric Composites, Puttakhun Meemai

Chulalongkorn University Theses and Dissertations (Chula ETD)

A green synthesis method was developed to produce biobased semiconducting composites of silver nanoparticles (AgNPs), skim natural rubber (SNR), and bacteria cellulose. A solution of silver nitrate (AgNO3) ranging from 40 to 160 mM was added to skim natural rubber latex (SNRL) to facilitate the reduction of silver ions to AgNPs at temperatures between 50 and 80 °C. Subsequently, BC pellicle was immersed in the prepared AgNPs-SNRL suspension for 48 hours, followed by washing and drying. The resulting AgNPs/SNR/BC films were then analyzed for their chemical, mechanical, antibacterial, and electrical properties. The strain at break of the films was significantly …

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Bi-Directional Evolutionary Structural Optimization For 3d-Printed Prefabricated Concrete Panels, Pochara Amornsittipipat Jan 2023

Bi-Directional Evolutionary Structural Optimization For 3d-Printed Prefabricated Concrete Panels, Pochara Amornsittipipat

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis seeks to develop an optimal design methodology for 3D-printed prefabricated concrete panels. Although 3D-printed precast panels are advantageous for producing flexible forms, reducing workforce demand, and minimizing environmental impacts, the product must not be too heavy to transport and install. Therefore, the consideration of weight emphasizes the need for structural optimization. This research presents truss-like structural modeling based on the properties of 3D-printed concrete, suggests an optimal design methodology using the Bi-directional Evolutionary Structural Optimization (BESO) algorithm to achieve minimum weight, conducts parametric studies to understand the relationship between significant parameters and the optimal weight achieved, and demonstrates …

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Development Of A Computer Vision System To Monitor Container Closures And Cleanliness Of Tools Related To Volatile Substances In Construction Projects, Tun Lin Naing Jan 2023

Development Of A Computer Vision System To Monitor Container Closures And Cleanliness Of Tools Related To Volatile Substances In Construction Projects, Tun Lin Naing

Chulalongkorn University Theses and Dissertations (Chula ETD)

Construction chemicals have gained an essential role across various aspects of the construction process in modern construction. While construction chemicals provide advantages to construction activities, if there are no control measures, they can transform into hazardous substances that pose occupational health risks and environmental impacts, which can also affect a company's ESG performance. Therefore, it is important to implement prevention and control measures for chemical materials during their utilization on construction sites to prevent the transformation of construction chemicals into hazardous substances. Currently, traditional methods of checking chemical containers and tools on construction sites are time-consuming, prone to errors, and …

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Deep Reinforcement Learning For Electricity Energy Trading On Non-Sharing Information Scenario, Nat Uthayansuthi Jan 2023

Deep Reinforcement Learning For Electricity Energy Trading On Non-Sharing Information Scenario, Nat Uthayansuthi

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this research, we explore an optimized model for peer-to-peer (P2P) energy trading within microgrids that addresses the gap in previous research, which often assumed mandatory sharing of private information among prosumers. Our model-based multi-agent deep reinforcement learning framework includes several key components: an LSTM for the policy model, ; the Temporal Fusion Transformer (TFT) for predicting 24h-ahead net load consumption, adept at handling multivariate time series data; the inclusion of the Global Horizontal Index (GHI) to account for solar irradiance to the model; and a clustering technique to segment the dataset of 300 households from the Ausgrid dataset in …

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Development Of Technetium-99m Labeled Psma For Spect Prostate Cancer Imaging, Kalapaphuk Tachatumvitoon Jan 2023

Development Of Technetium-99m Labeled Psma For Spect Prostate Cancer Imaging, Kalapaphuk Tachatumvitoon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Technetium-99m (Tc-99m) is the most employed radionuclide in nuclear imaging diagnosis because of its ideal physiochemical properties and ready availability. It particularly suitable for Single Photon Emission Computed Tomography (SPECT), leading to cost-effective compared to other radionuclides. This study consists of two aims to expand the utilization of Tc-99m radiopharmaceutical for prostate cancer which is one of the highest incidence rates and mortality cancer among men. Currently, Tc-99m radiopharmaceutical for SPECT diagnosis is not clinically available for prostate cancer. Firstly, the new formulation for Tc-99m complexation with PSMA-617, a current ligand for radionuclide therapy of prostate cancer with lutetium-177 (Lu-177), …

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Comparative Assessment Of Environmental And Post- Occupancy Evaluation Of Green Buildings Vs Conventional Buildings, Wint Thiri Marn Jan 2023

Comparative Assessment Of Environmental And Post- Occupancy Evaluation Of Green Buildings Vs Conventional Buildings, Wint Thiri Marn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Due to increasing office space demand and rising rental rates, stakeholders seek cost-effective alternatives that align with sustainability goals. Therefore, green building offers an extensive solution particularly in growing office building rental rates and the need for cost-effective options that are consistent with environmentally conscious goals. Using the IPCC standard, the study assessed emissions across Scope 1 (refrigerant fugitive emissions) and Scope 1 emission from (Wastewater treatment system), Scope 2 (energy consumption emissions), and Scope 3 (emissions from water consumption, and waste generation). Scope 1 emissions are found to vary due to the usage of water-based fire-retardant systems, but they …

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Sustainable Toughening Of Polylactic Acid With Ultra-Fine Fully Vulcanized Powdered Natural Rubber, Reza Gholami Jan 2023

Sustainable Toughening Of Polylactic Acid With Ultra-Fine Fully Vulcanized Powdered Natural Rubber, Reza Gholami

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study investigated the sustainable toughening of polylactic acid (PLA) by incorporating ultra-fine fully vulcanized powdered natural rubber graft-copolymerized with poly-styrene-co-acrylonitrile (UFPNR-SAN). We investigated the effect of the styrene-to-acrylonitrile ratio (ST:AN) used during the grafting process on the final UFPNR-SAN compatibility with PLA. The ST:AN ratio was systematically varied during the grafting reaction to prepare UFPNR-SAN with a range of different surface energies. The ST:AN ratio of 4:1 resulted in higher compatibility of UFPNR-SAN with the PLA matrix among other ratios. This could be explained by the desirable interfacial interactions and better dispersion shown by the contact angle measurements and …

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Real-Time Polyp Analysis On Endoscopic Images Using Deep Learning Approach: Detection, Characterization And Size Estimation, Phanukorn Sunthornwetchapong Jan 2023

Real-Time Polyp Analysis On Endoscopic Images Using Deep Learning Approach: Detection, Characterization And Size Estimation, Phanukorn Sunthornwetchapong

Chulalongkorn University Theses and Dissertations (Chula ETD)

As medical devices advance, doctors adopt endoscopes to perform endoscopes for gastrointestinal disease screenings. For colonoscopy, skills such as polyp detection, polyp characterisation, and polyp size estimation needed to be practised while screening patients. This work aims to develop a deep learning model for performing polyp detection, characterisation, and size estimation to assist fellow doctors in these tasks. To maximise usability in assisting fellow doctors, the model must be able to perform in a real-time fashion. The work utilises existing object detection models for performing size estimation tasks. With the problems of data imbalances, we use depth information but without …

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Shape Memory Polymer Based On Copolybenzoxazines: Effects Of Chain Length Of Aliphatic Monoamines On Shape Memory Performance, Attachai Sriwattana Jan 2023

Shape Memory Polymer Based On Copolybenzoxazines: Effects Of Chain Length Of Aliphatic Monoamines On Shape Memory Performance, Attachai Sriwattana

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research was successful in completely synthesizing benzoxazine copolymers for shape memory polymers (SMPs) by mixing bisphenol A-aniline (BA-a) and bisphenol A-aliphatic monoamines of various chain lengths (BA-aMAs). Our studies have shown that shorter chain lengths will provide higher crosslinking densities, which play an important role in promoting the stiffness of the polymer, resulting in a higher shape-fixity ratio (Rf). While longer chains result in a lower crosslinking density and a larger free volume, thus promoting a higher shape-recovery ratio (Rr), Therefore, selecting the appropriate aliphatic monoamine chain length is crucial. From the study of this work, it was found …

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Effects Of A Therapeutic Lifestyle Modification Intervention On Cardio-Metabolic Health, Sexual Functioning, And Health-Related Quality Of Life In Perimenopausal Chinese Women: A Randomized Controlled Trial, Yuru Wang Jan 2023

Effects Of A Therapeutic Lifestyle Modification Intervention On Cardio-Metabolic Health, Sexual Functioning, And Health-Related Quality Of Life In Perimenopausal Chinese Women: A Randomized Controlled Trial, Yuru Wang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: Our study aimed to explore the effects of a therapeutic lifestyle modification (TLM) intervention on cardiometabolic health, sexual functioning, and health-related quality of life in perimenopausal Chinese women. Methods: This was a 12-week, two-parallel arm, randomized controlled trial conducted in the First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming City, China. Ninety-four eligible perimenopausal women aged between 40 and 55 years were randomly assigned to either a TLM intervention or usual care at a 1:1 ratio. Menopause-specific quality of life (MENQOL), female sexual function index (FSFI), pelvic floor muscle strength (PFMS), and composite cardiometabolic biomarkers were evaluated …

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Comparison Of The Effects Of Dynamic Seat Cushion At Low Back And Buttocks On The Number Of Postural Shifts And Body Perceived Discomfort In Office Workers, Narumon Roynarin Jan 2023

Comparison Of The Effects Of Dynamic Seat Cushion At Low Back And Buttocks On The Number Of Postural Shifts And Body Perceived Discomfort In Office Workers, Narumon Roynarin

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study compared the number of postural shifts and body perceived discomfort while leaning and sitting on air-filled seat cushion for 1-hour in healthy office workers. Sixty office workers typed a standard text at a computer workstation for an hour in three sitting conditions: leaning on a seat cushion placing behind the low back, sitting on a seat cushion placing under the buttocks, and sitting without a seat cushion (a control condition). The number of postural shifts, average pressure (AP), peak pressure (PP), and frequency of sitting posture were collected using a seat pressure mat device. Body perceived discomfort at …

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Blended Program And Its Impact On Knowledge, Attitude And Help-Seeking Intention Of Conflict-Related Sexual Violence Among Internally Displaced People In Northern Myanmar Camps: A Quasi-Experimental Study, Chit Pyae Pyae Han Jan 2023

Blended Program And Its Impact On Knowledge, Attitude And Help-Seeking Intention Of Conflict-Related Sexual Violence Among Internally Displaced People In Northern Myanmar Camps: A Quasi-Experimental Study, Chit Pyae Pyae Han

Chulalongkorn University Theses and Dissertations (Chula ETD)

Introduction As a result of several military coups and internal armed conflicts, Myanmar has the longest history of civilian wars in the world. Human rights violations, gender-based violence, and sexual violence have become more widespread as a result of extensive conflicts and humanitarian crises. The United Nations is concerned about the detrimental consequences of sexual violence in military situations. A community-based program designed to prevent sexual violence is crucial in mitigating risk factors and enhancing protective factors Methods The two-group quasi-experimental study evaluated the impact of a community-based program to prevent sexual violence and examined the experiences of survivors among …

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Effects Of A Game On A Smartphone (“Pilotgold”)To Prevent Non-Specific Neck Pain Among Office Workers:A 6-Month Cluster-Randomised Controlled Trial, Natchanon Intipanya Jan 2023

Effects Of A Game On A Smartphone (“Pilotgold”)To Prevent Non-Specific Neck Pain Among Office Workers:A 6-Month Cluster-Randomised Controlled Trial, Natchanon Intipanya

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: To evaluate the effects of a smartphone game for active neck movement exercise on perceived neck discomfort, new onset neck pain, and active cervical range of motion (ROM) among high-risk office workers. Methods: A 6-month prospective cluster-randomized controlled trial was conducted involving 100 healthy but high-risk office workers from nine organizations. They were randomly assigned at the cluster level into either the intervention group (n = 50), who received a smartphone game to play twice a day on workdays for 6 months, or the control group (n = 50), who received a placebo seat pad to use while sitting. …

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Role Of Grb2 Intracellular Localization In Progesterone Receptor Positive Breast Cancer, Nattamolphan Wittayavimol Jan 2023

Role Of Grb2 Intracellular Localization In Progesterone Receptor Positive Breast Cancer, Nattamolphan Wittayavimol

Chulalongkorn University Theses and Dissertations (Chula ETD)

Progesterone receptor (PR) extranuclear signaling mediates mainly through PR polyproline domain (PPD) interaction with SH3 domain of cytoplasmic signaling molecules. PR-PPD interfered with Grb2-SOS binding through SH3 interaction resulting in decreased cell proliferation and correlates with a good prognosis in PR positive breast cancer. Grb2 is a key adaptor molecule and expressed in both nucleus and cytoplasm. We hypothesized that change in Grb2 localization alters PR transcription resulting in better clinical outcomes in PR positive breast cancer. BT-474 breast cancer cells expressing inducible Grb2-SV402x (nuclear Grb2, nuGrb2) or Grb2-MYR (membrane Grb2, memGrb2) were constructed. MemGrb2-BT-474 showed higher levels of PR …

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Knowledge, Attitude And Practice Of Human Papilloma Virus Vaccination Among Reproductive Age Women In Mandalay City, Myanmar: A Cross-Sectional Study, Kyi Thu Jan 2023

Knowledge, Attitude And Practice Of Human Papilloma Virus Vaccination Among Reproductive Age Women In Mandalay City, Myanmar: A Cross-Sectional Study, Kyi Thu

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cervical cancer is the fourth most common type of cancer among women all over the world. HPV infection, the most sexually transmitted viral infection, is responsible for about 95% of cases of cervical cancer. The study aims to investigate the association between socio-demographic characteristics, knowledge level, and attitude level toward the practice of HPV vaccination among reproductive age women in Mandalay City, Myanmar. The cross-sectional study was conducted in May 2024 among reproductive age women in Mandalay City in Myanmar. The study used an online, standard questionnaire. Descriptive statistics, simple logistic regression, and multiple logistics regression models were used for …

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Perception Of Academic Stress And Family Relationship On Mental Well-Being Among Pharmacy Students At Chulalongkorn University In Thailand: A Cross-Sectional Survey Study, Chompunoot Prasongpol Jan 2023

Perception Of Academic Stress And Family Relationship On Mental Well-Being Among Pharmacy Students At Chulalongkorn University In Thailand: A Cross-Sectional Survey Study, Chompunoot Prasongpol

Chulalongkorn University Theses and Dissertations (Chula ETD)

University students' mental health and well-being have gained more global attention due to their increasing influence on health and societal issues. The cross-sectional study, conducted in May 2024 among undergraduate Chulalongkorn University pharmacy students in Thailand, aims to investigate the proportion of mental well-being levels and determine the relationship between general characteristics, perceptions of academic stress, and family relationships toward mental well-being levels among pharmacy students at Chulalongkorn University. The study used an online, self-administered questionnaire. Descriptive statistics, simple logistic regression, and multiple logistic regression models were employed for data analysis. Out of 289 pharmacy students, 199 were predominantly female …

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Knowledge Attitude And Practice Of Who Mental Health Guidelines For Non-Specialist Primary Healthcare Providers In Wuhua District, Kunming, People's Republic Of China: A Cross-Sectional Study, Liesha Luohe Jan 2023

Knowledge Attitude And Practice Of Who Mental Health Guidelines For Non-Specialist Primary Healthcare Providers In Wuhua District, Kunming, People's Republic Of China: A Cross-Sectional Study, Liesha Luohe

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: The 'Healthy China 2030' policy emphasizes the importance of mental healthcare at the primary healthcare level. Globally, primary healthcare(PHC) service delivery is considered the most effective approach for managing mental health (MH) disorders. The WHO’s mental health gap intervention guide version 2 (mhGAP-IG.v2), is a decision support tool for non-specialists for the assessment, management, and follow-up of mental, neurological, and substance use disorders. However, no studies have assessed primary healthcare providers’ (HCPs) knowledge, attitudes, and practices on MH services in the western part of China. Objectives: To determine the PHC providers’ characteristics and MH service provision level in Wuhua …

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Ultrasound-Assisted Extraction Of Cannabis Sativa And Biological Activities Assessments For Dermatological Application, Pannita Kongtananeti Jan 2023

Ultrasound-Assisted Extraction Of Cannabis Sativa And Biological Activities Assessments For Dermatological Application, Pannita Kongtananeti

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cannabis sativa L. is a medicinal plant that has long been used in Thai traditional medicine and is still widely used today, with many uses in pharmaceuticals, including the treatment of skin infections. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type constituents, especially detla-9-tetrahydrocannabinol (THC), cannabidiol (CBD), and terpenes. However, fewer studies of cannabis have been reported regarding its anti-aging potential by investigating tyrosinase inhibition activity. In this study, ultrasound-assisted extraction (UAE) of 5 different parts of Cannabis sativa L., the determination of bioactive compounds using GC–MS/MS and the assessment of their biological properties related to …

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Associated Factors With Suicide Mortality In Thailand:A Mediating Roles Of Urban And Rural Areas, Kajohnsak Tangkwampien Jan 2023

Associated Factors With Suicide Mortality In Thailand:A Mediating Roles Of Urban And Rural Areas, Kajohnsak Tangkwampien

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Suicide is a global public health problem that affects individuals, families, and communities. The World Health Organization (WHO) estimates that more than 700,000 people die by suicide worldwide each year. Despite the significance of this issue, important factors like rural and urban settings, which have different definitions in each country and result in specific contextual effects on suicide, are overlooked. Objectives: To understand the role of living in urban and rural as mediator on the associated factors (socio-demographic factors, mental and physical problems, effect from COVID-19, economic factors, relationship problems, history of self-harm, and warning signs, method of suicide) …

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Association Between Greenness And Environmental Parameters Exposure And Depression Among Residents In Bangkok, Thailand: An Ecological Longitudinal Study, Wilaipak Nilsalai Jan 2023

Association Between Greenness And Environmental Parameters Exposure And Depression Among Residents In Bangkok, Thailand: An Ecological Longitudinal Study, Wilaipak Nilsalai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Depression and mental health issues are on the rise, and it is hypothesized that environmental factors may play a role in the development of these diseases. Greenness is one of the potential factors, and this study aims to investigate the relationship between living in greener areas and depression incidence in Bangkok. This is an ecological longitudinal study using secondary data documented between 2018 and 2020, utilizing data on depression (ICD-10 F32, F33), environmental parameters (PM2.5 (µg/m3), temperature (ºC), relative humidity (RH; %), and demographic variables (population density, number of communities, number of hospitals, number of healthcare centers, and divorce rate) …

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Effectiveness Of Facebook Breastfeeding Support Group On Exclusive Breastfeeding Among Myanmar Migrant Mothers In Samut Sakhon Province, Thailand: A Randomized Controlled Trial, Zayar Lynn Jan 2023

Effectiveness Of Facebook Breastfeeding Support Group On Exclusive Breastfeeding Among Myanmar Migrant Mothers In Samut Sakhon Province, Thailand: A Randomized Controlled Trial, Zayar Lynn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Given the widespread popularity of mobile health technology nowadays, conducting health education and behaviour change intervention through Facebook groups is a simple and efficient way to promote exclusive breastfeeding. However, limited studies have been investigating its effectiveness. This study aimed to assess the effectiveness of Facebook Breastfeeding Support Group on exclusive breastfeeding among Myanmar migrant mothers in Samut Sakhon Province, Thailand. A 2-arm, parallel-group, randomized controlled trial was conducted with 198 pregnant mothers between 28th and 34th weeks of gestation at the Antenatal Care clinic of Samut Sakhon Hospital. The intervention group (n=99) received breastfeeding related information and experience sharing …

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Application Of Machine Learning In Assessing Spatial Distribution Patterns Of Soil Microplastics: A Case Study Of The Bang Pakong Watershed, Thailand, Ugochukwu Ihezukwu Jan 2023

Application Of Machine Learning In Assessing Spatial Distribution Patterns Of Soil Microplastics: A Case Study Of The Bang Pakong Watershed, Thailand, Ugochukwu Ihezukwu

Chulalongkorn University Theses and Dissertations (Chula ETD)

Microplastics (MPs) are persistent environmental pollutants introduced through various factors. Understanding the spatial distribution characteristics of MPs is crucial for developing effective mitigation strategies. However, the relationship between MPs and their covariables remains largely unexplored. In this study, we investigated the abundance of MPs in 40 soil samples from different land-use types in the Bang Pakong Watershed and assessed the applicability of machine learning models for predicting the spatial distribution patterns of soil MPs. The samples were divided into three categories: 1.2 µm-500 µm, 500 µm-1 mm, and 1-2 mm. They were analyzed using ZnCl2 density separation, H2O2 digestion process, …

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Electrophysiological Characteristics Of A Novel Scn5a Mutation (I239v Or M1487k) In The Cardiac Voltage-Gated Sodium Channel, Vichaya Auvichayapat Jan 2023

Electrophysiological Characteristics Of A Novel Scn5a Mutation (I239v Or M1487k) In The Cardiac Voltage-Gated Sodium Channel, Vichaya Auvichayapat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cardiac voltage-gated sodium channels (NaV1.5) are essential to generate sodium current (INa) and regulate cardiac electrical conduction. Mutations in NaV1.5 can lead to cardiac disorders such as Brugada syndrome and Long QT Syndrome type 3 (LQTS3), potentially resulting in sudden cardiac death. Mutations p.I239V and p.M1487K have been identified in LQTS3 patients. The p.I239V mutation was found in a patient with mild symptoms and in family members who experienced sudden cardiac death, while the p.M1487K mutation is associated with more severe symptoms. This study aims to investigate the impact of these mutations on INa from NaV1.5 activities, which could cause …

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Superconductivity In 2d Janus Monolayers And Bilayers, M Munib Ul Hassan Noor Ul Taqi Jan 2023

Superconductivity In 2d Janus Monolayers And Bilayers, M Munib Ul Hassan Noor Ul Taqi

Chulalongkorn University Theses and Dissertations (Chula ETD)

Janus transition metal dichalcogenides (J-TMDCs) is a new class of materials which shares the same honey-comb structure as graphene and conventional transition metal dichalcogenides (TMDCs) in monolayer. They have versatile physical and chemical properties which mainly feature out from their broken out of plane symmetry. This asymmetry results in an intrinsic electric field orthogonal to their plan. The presence of an intrinsic electric field gives rise to many novel properties like the Rashba effect, increased charge carrier concentration, Schottky barrier, excitons, and superconductivity. Also, they exist in multiple structural phases like, 2H, 1T, 1T' with the electrical properties shifting from …

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การพัฒนาตัวชี้วัดเพื่อประเมินคุณภาพพื้นที่สีเขียวในประเทศไทย, ธนโชค วานิชผดุงธรรม Jan 2023

การพัฒนาตัวชี้วัดเพื่อประเมินคุณภาพพื้นที่สีเขียวในประเทศไทย, ธนโชค วานิชผดุงธรรม

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษาในครั้งนี้มีวัตถุประสงค์เพื่อพัฒนาตัวชี้วัดสำหรับประเมินคุณภาพพื้นที่สีเขียวและทดสอบประสิทธิภาพการใช้งาน การศึกษาทำโดย 1) กำหนดวัตถุประสงค์การใช้งานตัวชี้วัดและผู้ที่มีส่วนเกี่ยวข้อง, 2) รวบรวมตัวชี้วัดที่เกี่ยวข้อง, 3) วิเคราะห์และเลือกตัวชี้วัดที่เหมาะสม, 4) จัดทำเป็นแบบประเมิน และ 5) ทดสอบกับพื้นที่สีเขียวตัวอย่างจำนวน 15 แห่ง ได้แก่ ป่าธรรมชาติ/ป่าชุมชน 3 แห่ง สวนสาธารณะ 4 แห่ง พื้นที่ส่วนบุคคล 5 แห่ง และหลังคาเขียว 3 แห่ง ผลการศึกษาได้ตัวชี้วัดคุณภาพพื้นที่สีเขียวแบ่งเป็น 4 ด้าน ได้แก่ สภาพแวดล้อม ความหลากหลายทางชีวภาพ บริการของระบบนิเวศ และการจัดการในพื้นที่ รวม 124 ตัวชี้วัด 370 คะแนน ผลการใช้ตัวชี้วัดพบว่าคะแนนคุณภาพพื้นที่สีเขียวอยู่ในช่วงระหว่าง 296-152 คะแนน ซึ่งเป็นผลจากวัตถุประสงค์การใช้งานและลักษณะพื้นที่ที่มีความหลากหลาย คะแนนแต่ละด้านของพื้นที่สีเขียวแต่ละประเภทส่วนใหญ่มีความสัมพันธ์กับลักษณะพื้นที่ การดูแลและการใช้งานของมนุษย์ ในส่วนของการใช้งานพบว่าผู้ใช้งานมีความพึงพอใจแบบประเมินที่สร้างขึ้นโดยภาพรวมในระดับปานกลางถึงดี (3.73 ± 1.08 คะแนน) โดยเป็นผลจากการออกแบบการประเมินในรูปแบบรวดเร็ว มีการอำนวยความสะดวกในการบันทึกข้อมูลในโปรแกรม Microsoft Excel ใช้เวลาและกำลังคนในการประเมินต่ำ แต่แบบประเมินยังต้องพัฒนาคำอธิบายรายละเอียดและขั้นตอนใช้งานรวมถึงเกณฑ์การให้คะแนนเพิ่มเติม นอกจากนี้ ควรเพิ่มจำนวนพื้นที่สีเขียวที่ประเมินให้มากขึ้นเพื่อทดสอบและปรับปรุงประสิทธิภาพตัวชี้วัด ตลอดจนส่งเสริมให้ผู้มีส่วนเกี่ยวข้องกลุ่มต่าง ๆ นำไปใช้ประโยชน์เพื่อพัฒนาคุณภาพพื้นที่สีเขียวของประเทศต่อไป

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Inhibition Of Chondrocyte Apoptosis Via Fas/Fasl System In Knee Osteoarthritis Patients, Ousakorn Kamenkit Jan 2023

Inhibition Of Chondrocyte Apoptosis Via Fas/Fasl System In Knee Osteoarthritis Patients, Ousakorn Kamenkit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Osteoarthritis (OA) is a degenerative rheumatic disease characterized by articular cartilage degeneration. This articular cartilage degradation is positively correlated with chondrocyte apoptosis. The Fas/Fas ligand (FasL) system is part of the extrinsic apoptosis pathway that regulates cell death through the binding of Fas on target cells to FasL on effector cells. Although Fas+ chondrocytes have been identified and the Fas/FasL system has been implicated in this apoptotic process, the apoptosis through chondrocyte-to-FasL+ cell interaction remains unclear. Therefore, this study aims to investigate Fas/FasL-mediated chondrocyte apoptosis focusing on cell-to-cell interactions. In our study, we conducted ex vivo experiments using flow cytometry …

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Value-Added Natural Fiber As A Biocompatible Substrate For Chemical Sensor Applications, Wisarttra Phamonpon Jan 2023

Value-Added Natural Fiber As A Biocompatible Substrate For Chemical Sensor Applications, Wisarttra Phamonpon

Chulalongkorn University Theses and Dissertations (Chula ETD)

This dissertation focuses on the improvement and value added of natural fiber extracted from the UHT milk carton waste, and raw silk cocoon to fabricate the biocompatible substrate for chemical sensors, principally in colorimetric and electrochemical sensors, which is allocated in 3 main parts. Initially, the background studying of the surface modification and the function of natural fiber based chemical sensor for food quality control and clinical diagnosis will be explained in a review article. Subsequently, the development of recycled cellulose from UHT milk carton waste as a novel substrate of dual lactate sensor for milk spoilage indication will be …

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National Survey Of Human Epigenetic Study In Healthy Aged Population In Four Different Regions Of Thailand, Siwaporn Nilyai Jan 2023

National Survey Of Human Epigenetic Study In Healthy Aged Population In Four Different Regions Of Thailand, Siwaporn Nilyai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Healthy ageing has become a goal to help older people maintain good-quality longevity. Researchers have found that epigenetic, environmental, and behavioural lifestyle factors influence the variation of lifespan and healthspan. This study aims to evaluate the age-associated epigenetic biomarkers among older people living in four major regions of Thailand, along with their association with lifestyle and sociodemographic characteristics. 214 participants passed the criteria and enrolled from the southern, northeastern, central, and northern areas of Thailand. Sociodemographic characteristics were recorded through interviews, and blood samples were collected to evaluate blood chemistry and epigenetic markers. SIRT1 and HMGB1 proteins in plasma were …

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