Digital Commons Network^™

Achieving Warranted Acceptance Of Biotechnologies, Emily Grayek, Baruch Fischhoff

Level 3

The U.S. has faced long-standing shortages of generic drugs, causing negative health effects and spikes in drug costs. To address these shortages, investments in critical technologies and policies to support their adoption will be needed. The success of these technologies and policies depends on public acceptance. We studied public acceptance using the mental model approach, which identifies gaps in understanding that can be addressed with communications. We began with semi-structured interviews with experts in pharmaceutical manufacturing. Based on these interviews, we developed and conducted surveys of the general public, physicians, and pharmacists. Similar strategies could be applied to improve communications …

Exploring The Role Of Knowledge In The Pharma Workplace Of The Future: An Interactive Workshop Exploring Culture, Km And Opex, Stephanie Friedrichsen, Nuala Calnan (Editor), Martin J. Lipa

Level 3

This article presents a summary of an interactive workshop facilitated by Nuala Calnan and Stephanie Friedrichsen during the conference: ‘ICH Q9(R1): The Next Frontier’ held in Technological University Dublin, Ireland, on 1 June 2023. The summary was prepared by the workshop facilitators in conjunction with Martin Lipa who was a participant at the workshop. The article is written to give a high-level overview of the discussions which took place during the workshop and is not intended to be a complete representation of all the activities, insights and findings.

Leveraging Advanced Analytics In The Pharmaceutical Industry, Patrick O'Sullivan

Level 3

This article is a transcribed and lightly edited version of Patrick O’Sullivan’s oral presentation to a seminar hosted on 1 June 2023 by the Pharmaceutical Regulatory Science Team (PRST), TU Dublin, titled ICH Q9(R1): The Next Frontier – An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient. Patrick presented an overview of how one could leverage advanced analytics in the pharmaceutical Industry.

Valerie Mulholland On Improving Rbdm Effectiveness, Valerie Mulholland

Level 3

No abstract provided.

Speaker Bios

Level 3

No abstract provided.

Ipq Bibliography Pac Km Qrm 2010 - 2023

Level 3

No abstract provided.

Learn From The Past, Covid-19 And Beyond: The Case Of Türkiye, Gül Erkol Bayram, Ali Turan Bayram, Melike Sak

Journal of Mediterranean Tourism Research

The tourism sector has a delicate balance that is affected by its era. Political, economic, sociological problems and events affect the course of tourism, and when necessary, they can stop tourism movements. Epidemics affect tourism negatively. Covid-19 has a very different feature in terms of its effects on world tourism. In this context, the study examines the effects of Covid-19 on world and Turkish tourism. Within the scope of the study, related literature was reviewed, the effects of Covid-19 on world and Turkey tourism were examined with a qualitative approach. As a result, it can be expressed that travel restrictions …

Operating Fund Budget/ Expenditure Detail Report 2023-24, Csusb Budget Office

University Budget Office records

No abstract provided.

Human Genome Analysis And Encryption: A Cloud Prototype Model Using Aws And Aes, Priyanka Kunte, Rachana Shanbhogue, Sanjana S. Nayak, Neelima Bayyapu, Manjunath K N, Neha S. Gandhi

Manipal Journal of Science and Technology

SecureDNA presents a robust solution for safeguarding genetic data in cloud storage through the implementation of AES-256-CBC encryption. This innovative system, designed with a user-friendly interface, guides users seamlessly through DNA data upload processes, ensuring confidentiality and integrity. Utilizing AWS services such as RDS, VPC, and EC2, SecureDNA establishes a secure infrastructure for data storage and user interaction. By encrypting DNA records before storage and leveraging cloud computing benefits, this system not only protects sensitive genetic information but also offers scalability and accessibility. SecureDNA stands as a pivotal advancement in ensuring the privacy and reliability of genetic data in the …

Optimizing The Design Of An Ant-Shaped Millimetre-Wave Antenna For Broadband Applications: 9 To 100 Ghz, Lanston Pramith Fernandes, Harshitha M Raj, Dr. Manish Varun Yadav, Dr Swati Varun Yadav

Manipal Journal of Science and Technology

This article introduces a miniaturized antenna for 5G-II band millimetre-wave communication. The antenna’s performance is meticulously examined through comprehensive simulations carried out using CST Microwave Studio, employing an FR-4 substrate with dimensions measuring 10 × 12 × 1.5 mm3. The proposed design exhibits exceptional qualities, featuring an impressive impedance bandwidth of 166%. The operational frequency range of this antenna extends from 9.1 to 100 GHz, featuring a central frequency of 45.45 GHz, positioning it effectively within the 5G-II Band. The antenna consistently maintains polar patterns throughout this spectrum, which guarantees dependable and efficient performance. It showcases a substantial gain of …

Sustainable Food House Area (Sfha): Analysis Of Community Knowledge And Behavior, Delvi Adri, Mimien Henie Irawati, Sueb Sueb

Jurnal Pendidikan Sains

This research aimed to assess the knowledge and behavior of the community regarding the Sustainable Reserve Food Garden (SRFG) program. The study was conducted in July 2016 in Jorong Lubuk Agam, Kenagarian Ampang Kuranji Koto Baru, Dharmasraya, West Sumatra. Utilizing a descriptive quantitative approach, data were collected using Accidental Random Sampling, involving 33 heads of families as respondents. The findings revealed that community knowledge and behavior related to the SRFG program were generally insufficient, with 44.1% and 47.27% of respondents, respectively, demonstrating a lack of understanding and practice. The study concludes that approximately one-third of the population has limited knowledge …

Maurer Environmental Law Expert Is Lead Author On Science Insights Policy Forum Article, James Owsley Boyd

Keep Up With the Latest News from the Law School (blog)

Environmental champions and conservationists will mark the 50th anniversary of the Endangered Species Act later this month. That is the law requiring federal agencies to use all methods necessary to prevent extinctions and ensure that federal actions not jeopardize the continued existence of species on the brink of disappearing from the face of the Earth.

In the leadup to the December 27th anniversary, several publications have begun examining the Act’s history and impact over five decades.

Science, the world’s third-most influential scholarly journal based on Google Scholar citations, invited experts from around the country to look ahead as well …

The Presence Of Memory Through Materiality, Spatial Configuration, And Collective As A System For Sustainable High-Rise Residence, Arnis Rochma Harani, Brigitta E. Mekarwangi, Muhamad I. Hasan

CSID Journal of Infrastructure Development

This paper aims to explore the multifaceted elements involved in the design of residential buildings, encompassing both landed and high-rise structures, with a particular focus on memory. The ever-increasing urban population density has prompted a shift towards high-rise living, leading many individuals to transition from traditional landed homes. However, in urban environments where closely-knit communities have been the norm, high-rise living is often perceived as a potential obstacle to fostering social interactions akin to those experienced in landed residential areas. This challenge presents a compelling opportunity for designers to create vertical residential spaces that maintain the vibrant communal ambiance found …

Workplace Stress Of Special School Teachers At Three Schools In Bali Province, Made Adhyatma Prawira Natha Kusuma, Agnes Ayu Biomi, Luh Putu Wulandari Artha

Preventia: The Indonesian Journal of Public Health

Workplace stress is often seen as a threat or a problem that comes from the work environment. Stress is a feeling resulting from the interaction between the individual and the work environment. Work stress can happen to anyone at any time, including special school teachers. This research aims to describe the workplace stress of special school teachers at three schools in the Bali Province. This research was conducted in October-December 2022. Researcher used quantitative research method with cross-sectional design and descriptive approach. Data collection is carried out using the Copenhagen Psychosocial Questionnaire-III and the Occupational Diagnosis Survey from the Ministry …

Pagbasa At Paglapit Ng Anak Na Si Bayani S. Abadilla Sa Daigdig Ng Kaakuhan: Si Alejandro G. Abadilla At Ang Dakilang Pagwawasak, Romeo P. PeñA

Malay Journal

Sa pag-aaral na ito, tututukan ang naging pagbasa at paglapit ni Bayani S. Abadilla sa kaniyang amang si Alejandro G. Abadilla o AGA na tinaguriang rebeldeng manunulat sa kasaysayang pampanitikan ng Pilipinas at itinuturing na “Ama ng Modernong Panulaang Tagalog” sa ating bansa. Gamit ang akda ni B. Abadilla na may pamagat na “Ang Artista sa Dinamismo ng Sikohistorya” na nailathala noong 2003, naglalayon ang pag-aaral na ito na muling usisain ang ako at ang daigdig sa tulang “Ako ang Daigdig” ni AGA at muling sipatin ang kaakuhan ng rebeldeng makata na minsan nang pinagdudahan ng marami dahil tila mapang-angkin …

High-Risk Individuals And Naloxone Use: Implications For Thn Programs In Rural Appalachian Communities, Victor Garcia, Lisa Mccann, Erick Lauber, Christian Vaccaro, Melissa Swauger, Alex Daniel Heckert

Journal of Appalachian Health

Introduction: Take-home naloxone (THN) is being made available across rural Appalachia to curb opioid overdose fatalities. Despite this initiative, some opioid users do not possess naloxone, and if they do, do not administer it to others.

Purpose: Research findings on risk factors that contribute to opioid overdose are presented. These factors, identified in a sample of 16 overdose cases, are (1) early onset age of opioid use; (2) progressive opioid use; (3) a transition from pain medication to heroin and fentanyl; (4) fears of being arrested at a naloxone intervention if first responders are contacted, and (5) limited knowledge of …

Fighting Against Copyright Infringement On Social Networks In Vietnam - From The Perspective Of Responsibilities Of Internet Service Providers, Phan Khoi Nguyen

Indonesia Law Review

The law on intellectual property in general and copyright, in particular, is a subject of increasing interest in today's society, particularly in the information and internet explosion era. To prevent infringement and effectively protect copyright in the online environment, Vietnam's copyright law contains numerous provisions, including regulations pertaining to service provider responsibilities. This article examines the international and domestic legal bases for the liability of social network service providers (a type of internet-based intermediary service) in the fight against harmful copyright violations by the users of the service. Thus, the authors will identify several deficiencies in the existing Vietnamese copyright …

Narrating The Act Of Truth In The Jataka And Avadana Reliefs At Candi Borobudur, So Tju Shinta Lee

Paradigma: Jurnal Kajian Budaya

This paper analyzes the Act of Truth in nine Jataka and Avadana stories depicted in Candi Borobudur, Central Java, aiming to identify its key factors and purpose in the allegories. Through content analysis and comparative analysis, the study finds that merit, right speech, and intention are the primary contributing factors to the Act of Truth. A beneficial Act of Truth involves taking a firm stance on truth, driven by compassion to benefit others and attain one’s highest potential. The findings suggest that the acts in these stories form a part of the bodhisattva’s path to achieving perfect awakening. This study …

Educating Good Moral Values Through Video Game: Harvest Moon Back To Nature Perspectives, Fikry Prastya Syahputra, Mahmud Arief Albar

Paradigma: Jurnal Kajian Budaya

Globalization makes cultural absorption faster, but this also has a negative effect if the culture exposed is unsuitable. This will also affect the morale of a generation. One media that can spread culture and moral values is video games. For example, in a role-playing game genre which makes the players act like it is their real life, they can grasp many valuable experiences. Therefore, this study aims to identify the moral values in a video game called Harvest Moon: Back to Nature. Harvest Moon: Back to Nature or HM BTN is a role-playing game in which the player acts as …

Generation Z’S Perception Of Javanese Oral Tradition Of Myth And Taboo Ora Ilok In Javanese Society, Tira Nur Fitria

Paradigma: Jurnal Kajian Budaya

The various myth and taboos of ora ilok are familiar among several Javanese groups. The objective of this research is to understand generation Z’s perception of the Javanese myth and taboo ora ilok in Javanese society. This research employs the descriptive qualitative method, involving 76 respondents from various regions of Java such as Central Java, East Java, West Java, and the Special Region of Yogyakarta. The respondents were born between 1996 and 2005. Results show that the majority of respondents do not believe in the ora ilok myths. However, there is a different opinion from Generation Z. Some consider myths …

How Covid-19 Affects Libraries In Mongolia, Tseren Ganbaatar Dr., Associate Professor, Narantuya Otgondoo, Zolboo Mashbat

Paradigma: Jurnal Kajian Budaya

Globally, the COVID-19 pandemic has significantly impacted all spheres of the education industry, including libraries. The absence of emergency plans for unforeseen situations like COVID-19 disrupted regular operation and demanded the adoption of new operational protocols. The objectives of this paper are to examine the impact of COVID-19 on library operations, to identify the challenges encountered in libraries, to examine the changes in users’ service preference, and to reflect on the best practice for library operations in the future. To achieve these research objectives, both qualitative and quantitative research methods were employed. Surveys and interviews were conducted to understand changes …

Social-Emotional Learning: Preschool Teachers’ Perspectives From Urban And Rural Contexts, Seema Lasi, Khushal Khan, Noreen Afzal

Human Development Programme

Social-emotional learning (SEL) is an integral part of holistic child development. The early years of life are the best window of opportunity when children acquire self-regulation which stays with them throughout their lives. A qualitative exploratory design with focus group discussions (FGDs) was used for preschool teachers’ perspectives on SEL from urban and rural areas of Pakistan. Five (5) FGDs were organized, each with 8 to 10 teachers. Insights were highlighted by teachers from urban and rural contexts. Urban schoolteachers demonstrated a better understanding of SEL as compared to rural schoolteachers. The main themes identified during the analysis were teachers' …

Analyzing A Smartphone Battle Using Bass Competition Model, Maila Hallare, Alireza Hosseinkhan, Hasala Senpathy K. Gallolu Kankanamalage

CODEE Journal

Many examples of 2x2 nonlinear systems in a first-course in ODE or a mathematical modeling class come from physics or biology. We present an example that comes from the business or management sciences, namely, the Bass diffusion model. We believe that students will appreciate this model because it does not require a lot of background material and it is used to analyze sales data and serve as a guide in pricing decisions for a single product. In this project, we create a 2x2 ODE system that is inspired by the Bass diffusion model; we call the resulting system the Bass …

Beta Cell Primary Cilia Mediate Somatostatin Responsiveness Via Sstr3, Samantha E Adamson, Zipeng A Li, Jing W Hughes

2020-Current year OA Pubs

Somatostatin is a paracrine modulator of insulin secretion and beta cell function with pleotropic effects on glucose homeostasis. The mechanism of somatostatin-mediated communication between delta and beta cells is not well-understood, which we address in this study via the ciliary somatostatin receptor 3 (SSTR3). Primary cilia are membrane organelles that act as signaling hubs in islets by virtue of their subcellular location and enrichment in signaling proteins such as G-protein coupled receptors (GPCRs). We show that SSTR3, a ciliary GPCR, mediates somatostatin suppression of insulin secretion in mouse islets. Quantitative analysis of calcium flux using a mouse model of genetically …

Is A Ban On Non-Competes Supported By Empirical Evidence?, Sarah Oh Lam, Thomas Lenard, Scott Wallsten

Fordham Journal of Corporate & Financial Law

The U.S. Federal Trade Commission (FTC) has proposed a rule to declare virtually all non-compete agreements unfair methods of competition under Section 5 of the FTC Act and therefore, illegal. However, the empirical literature on non-compete agreements cited by the FTC in its Notice for Proposed Rulemaking (“NPRM”) shows mixed results on earnings, job creation, firm formation, entrepreneurship, training, investment, and firm value. Evidence in other current studies also does not support an economy-wide ban. The FTC concludes that the proposed rule would yield net benefits even though by its own admission it lacks the information necessary to conduct a …

Outsourcing Voting To Ai: Can Chatgpt Advise Index Funds On Proxy Voting Decisions?, Chen Wang

Fordham Journal of Corporate & Financial Law

Released in November 2022, Chat Generative Pre-training Transformer (“ChatGPT”), has risen rapidly to prominence, and its versatile capabilities have already been shown in a variety of fields. Due to ChatGPT’s advanced features, such as extensive pre-training on diverse data, strong generalization ability, fine-tuning capabilities, and improved reasoning, the use of AI in the legal industry could experience a significant transformation. Since small passive funds with low-cost business models generally lack the financial resources to make informed proxy voting decisions that align with their shareholders’ interests, this Article considers the use of ChatGPT to assist small investment funds, particularly small passive …

Indigenous Engagement With The Alexander Archipelago Wolf: Cultural Context And Traditional Ecological Knowledge, Stephen J. Langdon, Jeffrey J. Brooks, Tim Ackerman, Devlin Shaag̱ Anderstrom, Eldon C. Atkinson, Michael Gitwaayne Douville, Thomas Allen George, Stanley Yeilwú Hotch, Michael Kauish Jackson, Nathan Jackson, Richard Jackson, Scott Gus’Tú Jackson, John Kéet Katzeek, Thomas Mills, Judith Dax̱Ootsú Ramso, Jon Rowan, Tony Sanderson, Chuck Smythe, Sidney C. Edenshaw

Faculty, Staff, and Students

The U.S. Fish and Wildlife Service in Alaska conducted a Species Status Assessment in response to a petition to list the Alexander Archipelago wolf under the Endangered Species Act. This federal undertaking could not be adequately prepared without including the voices of the Indigenous People who have a deep connection with the subspecies. The Indigenous knowledge presented in this report is the cultural and intellectual property of those who have shared it. The purpose of the report is to communicate the knowledge shared with us to the U.S. Fish and Wildlife Service to help inform the Species Status Assessment and …

Spatial Analysis Of The Distribution Of Covid-19 Vulnerable Groups To Covid-19 Cases In Brebes Regency, Fatimatuzzahro Fatimatuzzahro, Rara Warih Gayatri

Preventia: The Indonesian Journal of Public Health

The number of COVID-19 cases in Brebes Regency within a year is still quite high. The elderly, Hypertension and Diabetes Mellitus are the most important COVID-19 vulnerable groups and have the highest risk of death. The purpose of this study is to determine the distribution of COVID-19 vulnerable groups and their spatial relationship to COVID-19 cases in Brebes Regency. This study used a correlation or ecology study design. The data used is secondary data obtained from the Brebes Regency Health Office, namely the number of COVID-19 cases, the number of elderly, people with hypertension and diabetes mellitus in 2021. The …

Relative Comparison Of Modern Computing To Computer Technology Of Ages, Iwasan D. Kejawa Dr., Hailly Rubio Ms.

School of Computing: Faculty Publications

Abstract

Abstract

Are there differences and similarities between the computer technology of today and yesterdays. Research had shown that there had been tremendous improvements from the computers of ages (traditional Computers) as we enter the 21st century. Both the physicality and the functionalities of computers have changed but some remain the same. The memory capacity and functions have changed, but all are still based on the old concepts of yesteryears.

Systematic Review Of The Relationship Between Hygiene Practice And The Incidence Of Ascaris Lumbricoides Infection In Southeast Asian Children, Anastasia Rouli Alodia, Ririn Arminsih Wulandari

Preventia: The Indonesian Journal of Public Health

Soil-Transmitted Helminth (STH) infection is one of the Neglected Tropical Diseases (NTDs) that affects around 1.5 billion people worldwide, including regions like Southeast Asia. The most common species infecting humans is Ascaris lumbricoides. Preschool-age and school-age children are particularly vulnerable to STH infection due to their living environments in areas where STH is prevalent. Infection of STH, especially Ascaris lumbricoides, can hinder physical and cognitive development and, in severe cases, cause obstruction of the small intestine. Various factors, such as hygiene practices, can influence the transmission of Ascaris lumbricoides infection in children. This study aims to explore the association between …