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Articles 331 - 360 of 38583
Full-Text Articles in Entire DC Network
Svm-Do: Identification Of Tumor-Discriminating Mrna Signatures Via Support Vectormachines Supported By Disease Ontology, Mustafa Erhan Özer, Pemra Özbek Sarica, Kazim Yalçin Arğa
Svm-Do: Identification Of Tumor-Discriminating Mrna Signatures Via Support Vectormachines Supported By Disease Ontology, Mustafa Erhan Özer, Pemra Özbek Sarica, Kazim Yalçin Arğa
Turkish Journal of Biology
Background/aim: The complicated nature of tumor formation makes it difficult to identify discriminatory genes. Recently, transcriptome-based supervised classification methods using support vector machines (SVMs) have become popular in this field. However, the inclusion of less significant variables in the construction of classification models can lead to misclassification. To improve model performance, feature selection methods such as enrichment analysis can be used to extract useful variable sets. The detection of genes that can discriminate between normal and tumor samples in the association of cancer and disease remains an area of limited information. We therefore aimed to discover novel and practical sets …
Suma: A Lightweight Machine Learning Model Powered Shared Nearest Neighbour Based Clustering Application Interface Of Scrna-Seq, Hamza Umut Karakurt, Pınar Pir
Suma: A Lightweight Machine Learning Model Powered Shared Nearest Neighbour Based Clustering Application Interface Of Scrna-Seq, Hamza Umut Karakurt, Pınar Pir
Turkish Journal of Biology
Background/aim: Single-cell transcriptomics (scRNA-Seq) explores cellular diversity at the gene expression level. Due to the inherent sparsity and noise in scRNA-Seq data and the uncertainty on the types of sequenced cells, effective clustering and cell type annotation are essential. The graph-based clustering of scRNA-Seq data is a simple yet powerful approach which presents data as a “shared nearest neighbour” graph and clusters the cells using graph clustering algorithms. These algorithms are dependent on several user-defined parameters. Here we present SUMA, a lightweight tool that uses a random forest model to predict the optimum number of neighbours to have the optimum …
Physicochemical Differences Between Camelid Single-Domain Antibodies And Mammalian Antibodies, Nazli Eda Eski̇er, Doğa Eski̇er, Esi̇n Fi̇ruzan, Si̇bel Kalyoncu
Physicochemical Differences Between Camelid Single-Domain Antibodies And Mammalian Antibodies, Nazli Eda Eski̇er, Doğa Eski̇er, Esi̇n Fi̇ruzan, Si̇bel Kalyoncu
Turkish Journal of Biology
Background/aim: In recent years, single-domain antibodies, also known as nanobodies, have emerged as an alternative to full immunoglobulin Gs (IgGs), due to their various advantages including increased solubility, faster clearance, and cheaper production. Nanobodies are generally derived from the variable domain of the camelid heavy-chain-only immunoglobulin Gs (hcIgGs). Due to the high sequence homology between variable heavy chains of camelids (VHHs) and humans (VHs), hcIgGs are ideal candidates for nanobody development. However, further examination is needed to understand the structural differences between VHs and VHHs. This analysis is essential for nanobody engineering to mitigate potential immunogenicity while preserving stability, functionality, …
How To Deliver An Effective Course: A Student's Perspective, Jaipaul Udaipaul, Lynne N. Kennette
How To Deliver An Effective Course: A Student's Perspective, Jaipaul Udaipaul, Lynne N. Kennette
Journal of Educational Research and Practice
Certain course features, such as engaging delivery, can benefit student learning. This essay presents one student’s opinion of what made for an effective introductory psychology course. The student provides his perspective on various features of the recently completed psychology course and how those elements supported his learning. The elements he identified included various ongoing knowledge checks, test reviews, tests, in-class engagement, personalized touchpoints, scaffolding, and student feedback. For each, the course instructor explains the pedagogical underpinnings of her choices. Faculty may find a student’s perspective on courses valuable as they consider their pedagogical decisions in terms of course design and …
Blue Economic Potency Of Marine Invertebrates For Bio-Drug Discovery, Hassan A.H. Ibrahim, Hanan M. Abdelnaby, Samia S. Abouelkheir, Hamdy A. Abo-Taleb, Nermeen A. El Sersy
Blue Economic Potency Of Marine Invertebrates For Bio-Drug Discovery, Hassan A.H. Ibrahim, Hanan M. Abdelnaby, Samia S. Abouelkheir, Hamdy A. Abo-Taleb, Nermeen A. El Sersy
Blue Economy
In terms of focus, promising results obtained from extensive investigations showed that the biodiversity of marine invertebrates has been documented. This poses the marine ecosystem as a hopeful resource in the discovery of novel compounds, with an ideal starting point in scaffolding additional screening of marine natural products (MNPs), especially to face the rise in the burden of diseases and treatment failure. A wide range of antimicrobial, antiviral, anticancer, anti-inflammatory, antiparasitic, neuroprotective, analgesic, antimalarial and other agents of marine origin have been pursued in the control and management of diseases. In the current review, we will focus on figuring out …
Ultradeformable Nanocarriers For Efficient Transdermal Drug Delivery, Hala N. Elshagea, Rana R. Makar, Alaa H. Salama, Nermeen A. Elkasabgy, Emad B. Basalious
Ultradeformable Nanocarriers For Efficient Transdermal Drug Delivery, Hala N. Elshagea, Rana R. Makar, Alaa H. Salama, Nermeen A. Elkasabgy, Emad B. Basalious
Bulletin of Faculty of Pharmacy Cairo University
Ultradeformable nanovesicles (UDVs) have recently become one of the favorable tools used for the transdermal delivery of drugs into deep skin layers, leading to enhanced bioavailability and therapeutic effect. UDV are capable of carrying hydrophilic, lipophilic or amphiphilic drugs bypassing the skin barriers. This mini review presents examples of UDV, their advantages, different mechanisms for UDV skin penetration, and some of the recent studies that proved the liability of using such carriers for better skin penetration. The applicability of using UDV for transdermal drug delivery has expanded such that marketed drug products were recently approved and launched indicating its superiority …
Outdoor Position Recovery From Heterogeneous Telco Cellular Data, Yige Zhang, Weixiong Rao, Kun Zhang, Lei Chen
Outdoor Position Recovery From Heterogeneous Telco Cellular Data, Yige Zhang, Weixiong Rao, Kun Zhang, Lei Chen
Machine Learning Faculty Publications
Recent years have witnessed unprecedented amounts of data generated by telecommunication (Telco) cellular networks. For example, measurement records (MRs) are generated to report the connection states between mobile devices and Telco networks, e.g., received signal strength. MR data have been widely used to localize outdoor mobile devices for human mobility analysis, urban planning, and traffic forecasting. Existing works using first-order sequence models such as the Hidden Markov Model (HMM) attempt to capture spatio-temporal locality in underlying mobility patterns for lower localization errors. The HMM approaches typically assume stable mobility patterns of the underlying mobile devices. Yet real MR datasets exhibit …
Social Media Utilization Of Public Benefit Organizations During The Covid-19 Pandemic, Piotr Szamrowski, Marian Oliński
Social Media Utilization Of Public Benefit Organizations During The Covid-19 Pandemic, Piotr Szamrowski, Marian Oliński
European Management Studies
Purpose: The main purpose of the research was twofold. First, it was to assess the impact of the COVID-19 pandemic on the publishing activity of Polish public benefit organizations on Facebook. Second, to determine the impact of content published in a crisis situation on the public reaction. Design/methodology/approach: During the investigation, the financial reports of public benefit organizations were analyzed. Farther the basic parameters of the organization’s Facebook profile and the content published on Facebook were analyzed (1025 organizations were covered by the research). From the reports, financial data of organizations has been collected. Both in 2020 and in 2021, …
Physics Ii, Kalani Hettiarachchilage
Physics Ii, Kalani Hettiarachchilage
Open Educational Resources
Physics II, class code PHY 156 at College of Staten Island is the second part of two two-semester algebra-based introductory physics courses. This course overlaps of the following topics laws of electricity, magnetism, optics, and modern physics. The important laws of physics in these areas and problem-solving are emphasized. Problem solving is an integral part of the course, all contents are designed to think critically, analytically, and logically. Conceptual understanding is reinforced using interactive computer-based techniques, demonstrations, problem-solving strategies, and laboratory experiences. In this document, all the class materials including lectures, worksheets, homework, group work assignments, quizzes, and conceptual Slido …
The Deconfinement Phase Transition In $Sp(2n)$ Gauge Theories And The Density Of States Method, David Mason, Biagio Lucini, Maurizio Piai, Enrico Rinaldi, Davide Vadacchino
The Deconfinement Phase Transition In $Sp(2n)$ Gauge Theories And The Density Of States Method, David Mason, Biagio Lucini, Maurizio Piai, Enrico Rinaldi, Davide Vadacchino
School of Engineering, Computing and Mathematics
First-order phase transitions in the early universe might produce a detectable background ofgravitational waves. As these phase transitions can be generated by new physics, it is importantto quantify these effects. Many pure Yang-Mills gauge theories are known to undergo first-orderdeconfinement phase transitions, with properties that can be studied with lattice simulations.Despite the recent surge of interest in ����(2��) gauge theories as a candidate for models of physicsbeyond the standard model, studies of these theories at finite temperature are still very limited. Inthis contribution we will present preliminary results of an ongoing numerical investigation of thethermodynamic properties of the deconfinement phase …
Lattice Studies Of Sp(2n) Gauge Theories Using Grid, Niccolo Forzano, Ed Bennett, Peter Boyle, Jong-Wan Lee, Julian Lenz, Biagio Lucini, Alessandro Lupo, Maurizio Piai, Davide Vadacchino, Luigi Del Debbio, Deog Ki Hong, C.-J David Lin
Lattice Studies Of Sp(2n) Gauge Theories Using Grid, Niccolo Forzano, Ed Bennett, Peter Boyle, Jong-Wan Lee, Julian Lenz, Biagio Lucini, Alessandro Lupo, Maurizio Piai, Davide Vadacchino, Luigi Del Debbio, Deog Ki Hong, C.-J David Lin
School of Engineering, Computing and Mathematics
No abstract provided.
Writing Centers & The Dark Warehouse University: Generative Ai, Three Human Advantages, Joe Essid
Writing Centers & The Dark Warehouse University: Generative Ai, Three Human Advantages, Joe Essid
Interdisciplinary Journal of Leadership Studies
Institutions are scrambling, at an unaccustomed pace, to adapt to generative artificial intelligence. While justified concerns focus on plagiarism, the nature of student learning, and changes to assignments, recent scholarship has largely ignored the potential for faculty and staff unemployment that may accompany acceptance and deployment of the new technology. As we ponder seismic changes in higher education, one voice should join, indeed lead, campus discussions. Writing center professionals have proven adept at weathering technological changes, budget cuts, administrative big ideas, and professional marginalization for more than half a century. Early on, centers were sometimes dismissed as mere “fix-it shops” …
Structural Basis For Dna Proofreading, Gina Buchel, Ashok Nayak, Karl Herbine, Azadeh Sarfallah, Viktoriia Sokolova, Angelica Zamudio-Ochoa, Dmitry Temiakov
Structural Basis For Dna Proofreading, Gina Buchel, Ashok Nayak, Karl Herbine, Azadeh Sarfallah, Viktoriia Sokolova, Angelica Zamudio-Ochoa, Dmitry Temiakov
Department of Biochemistry and Molecular Biology Faculty Papers
DNA polymerase (DNAP) can correct errors in DNA during replication by proofreading, a process critical for cell viability. However, the mechanism by which an erroneously incorporated base translocates from the polymerase to the exonuclease site and the corrected DNA terminus returns has remained elusive. Here, we present an ensemble of nine high-resolution structures representing human mitochondrial DNA polymerase Gamma, Polγ, captured during consecutive proofreading steps. The structures reveal key events, including mismatched base recognition, its dissociation from the polymerase site, forward translocation of DNAP, alterations in DNA trajectory, repositioning and refolding of elements for primer separation, DNAP backtracking, and displacement …
A Critical Computing Curriculum Design Case: Exploring Tribal Sovereignty For Middle School Students, Kristin A. Searle, Aubrey Rogowski, Colby Tofel-Grehl, Mengying Jiang
A Critical Computing Curriculum Design Case: Exploring Tribal Sovereignty For Middle School Students, Kristin A. Searle, Aubrey Rogowski, Colby Tofel-Grehl, Mengying Jiang
Journal of Computer Science Integration
We report on our efforts to design an integrated computing curriculum for middle school students in Montana that is in line with the Kapor Center’s focus on culturally sustaining-revitalizing pedagogies. Montana provides a unique context for doing this work because a state constitutional mandate requires all K-12 students to learn about tribal histories and cultures through Indian Education For All (IEFA). IEFA centers around seven essential understandings about Indigenous peoples in Montana that are integrated across content areas. In addition, implementation of Montana’s CS standards began in the 2021–2022 school year. In the curricular design, we sought to bring together …
Review On Therapeutic Potential Of Phytochemicals From Medicinal Plants, Iqra Afzal, Ume Habiba, Humaira Yasmeen
Review On Therapeutic Potential Of Phytochemicals From Medicinal Plants, Iqra Afzal, Ume Habiba, Humaira Yasmeen
Journal of Bioresource Management
Nature has provided plants with a vast range of phytochemicals. These phytochemicals are enriched with different pharmacological activities. These pharmacological activities have a potential to be wisely used for therapeutic purpose. It can be utilized in so many ways for the expansion of therapeutic strategies. With the advancement in the field of medicine and due to increasing side effects of synthetic medicines there emerges a need to discover novel therapeutic remedies. Medicinal plants serve as the best source for the manufacture of new remedies for many diseases. Medicinal plants bear a potential towards treating incurable chronic diseases. The aim of …
Chimera Baryon Spectrum In The Sp(4) Completion Of Composite Higgs Models, Ho Hsiao, Ed Bennett, Deog Ki Hong, Jong-Wan Lee, C.-J. David Lin, Biagio Lucini, Maurizio Piai, Davide Vadacchino
Chimera Baryon Spectrum In The Sp(4) Completion Of Composite Higgs Models, Ho Hsiao, Ed Bennett, Deog Ki Hong, Jong-Wan Lee, C.-J. David Lin, Biagio Lucini, Maurizio Piai, Davide Vadacchino
School of Engineering, Computing and Mathematics
In strongly coupled gauge theories that serve as completions of composite Higgs models, thefermionic bound states formed by fermions (hyperquarks) transforming in different representations, called chimera baryons, could serve as top partners, by embedding of the Standard Modelappropriately. We report our results on the spectrum of chimera baryons in the �� ��(4) gauge theorywith hyperquarks transforming in fundamental and two-index antisymmetric representations. Forthis study, we adopt the quenched approximation. We investigate the mass hierarchy between thelightest chimera baryons with different quantum numbers, as a function of the lattice parameters.Inspired by baryon chiral effective field theory, and the Akaike Information Criterion, …
Single-Pulse Electrical Stimulation Artifact Removal Using The Novel Matching Pursuit-Based Artifact Reconstruction And Removal Method (Mparrm), Tao Xie, Thomas J Foutz, Markus Adamek, James R Swift, Cory S Inman, Joseph R Manns, Eric C Leuthardt, Jon T Willie, Peter Brunner
Single-Pulse Electrical Stimulation Artifact Removal Using The Novel Matching Pursuit-Based Artifact Reconstruction And Removal Method (Mparrm), Tao Xie, Thomas J Foutz, Markus Adamek, James R Swift, Cory S Inman, Joseph R Manns, Eric C Leuthardt, Jon T Willie, Peter Brunner
2020-Current year OA Pubs
No abstract provided.
Automation And Optimization Of Industrial Scale Essential Oil Extraction From Citrus Peel Using A Neutrosophic Control System Model, Manuel Michael Beraún-Espíritu, Ketty Marilú Moscoso-Paucarchuco, Luis Enrique Espinoza-Quispe, Fabricio Miguel Moreno-Menéndez, Jesús César Sandoval-Trigos, Edson Hilmer Julca-Marcelo, Bheny Janett Tuya-Cerna, Edgar Gutiérrez-Gómez
Automation And Optimization Of Industrial Scale Essential Oil Extraction From Citrus Peel Using A Neutrosophic Control System Model, Manuel Michael Beraún-Espíritu, Ketty Marilú Moscoso-Paucarchuco, Luis Enrique Espinoza-Quispe, Fabricio Miguel Moreno-Menéndez, Jesús César Sandoval-Trigos, Edson Hilmer Julca-Marcelo, Bheny Janett Tuya-Cerna, Edgar Gutiérrez-Gómez
Neutrosophic Sets and Systems
No abstract provided.
A Hybrid Of Aras And Neutrosophic 2-Tuple Linguistic Model To Evaluate Gender Equitable Policies From The Perspective Of Latin American Professor’S, Katia Ninozca Flores-Ledesma, María Eugenia Navas Rios, Carlos Oswaldo Venturo Orbegoso, Myriam Griselda Lora Loza, Claudia Milena Gómez-Zuluaga, Mónica Elisa Meneses-La Riva, Ana María Vallina-Hernández, Willian Sebastián Flores-Sotelo
A Hybrid Of Aras And Neutrosophic 2-Tuple Linguistic Model To Evaluate Gender Equitable Policies From The Perspective Of Latin American Professor’S, Katia Ninozca Flores-Ledesma, María Eugenia Navas Rios, Carlos Oswaldo Venturo Orbegoso, Myriam Griselda Lora Loza, Claudia Milena Gómez-Zuluaga, Mónica Elisa Meneses-La Riva, Ana María Vallina-Hernández, Willian Sebastián Flores-Sotelo
Neutrosophic Sets and Systems
No abstract provided.
A Comparative Study Based On Neutrosophic Numbers And The Indeterminate Vikor Method For The Selection Of Three Types Of Vertical Axis Wind Turbines Adapted To The Conditions Of Peru, David Elvis Condezo Hurtado, Becquer Frauberth Camayo-Lapa, José Eduardo Galarza-Linares, Brecio Daniel Lazo-Baltazar, Armando Felipe Calcina Sotelo, Adrián Becquer Camayo-Vivas, Bartolomé Sáenz Loayza, Miguel Ángel Quispe Solano
A Comparative Study Based On Neutrosophic Numbers And The Indeterminate Vikor Method For The Selection Of Three Types Of Vertical Axis Wind Turbines Adapted To The Conditions Of Peru, David Elvis Condezo Hurtado, Becquer Frauberth Camayo-Lapa, José Eduardo Galarza-Linares, Brecio Daniel Lazo-Baltazar, Armando Felipe Calcina Sotelo, Adrián Becquer Camayo-Vivas, Bartolomé Sáenz Loayza, Miguel Ángel Quispe Solano
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Assessment Of Corporate Responsibility In Ecuador's Environmental Context, Carlos Gilberto Rosero Martínez, Ingrid Joselyne Díaz Basurto, Francisco Alejo Guanoluisa Almache, Jean Pierre Ramos Carpio
Neutrosophic Assessment Of Corporate Responsibility In Ecuador's Environmental Context, Carlos Gilberto Rosero Martínez, Ingrid Joselyne Díaz Basurto, Francisco Alejo Guanoluisa Almache, Jean Pierre Ramos Carpio
Neutrosophic Sets and Systems
No abstract provided.
Plithogenic Iadov Model To Study University Teaching Practices In The Complexity Of The Educational Process Of Comprehensive Training By Competencies, Pedro Barrientos Gutiérrez, Katia Ninozca Flores-Ledesma, Santos Lucio Guanilo Gómez, Jorge Luis López Bulnes, Jorge Leonardo Jave Nakayo, Carlos Francisco Cabrera Carranza, Abrahan Cesar Neri Ayala
Plithogenic Iadov Model To Study University Teaching Practices In The Complexity Of The Educational Process Of Comprehensive Training By Competencies, Pedro Barrientos Gutiérrez, Katia Ninozca Flores-Ledesma, Santos Lucio Guanilo Gómez, Jorge Luis López Bulnes, Jorge Leonardo Jave Nakayo, Carlos Francisco Cabrera Carranza, Abrahan Cesar Neri Ayala
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Methods In Corporate Social Responsibility, Gustavo Adolfo Alvarez Gómez, Corona Gómez Armijos, Ariel Romero Fernández, Karina Pérez Teruel
Neutrosophic Methods In Corporate Social Responsibility, Gustavo Adolfo Alvarez Gómez, Corona Gómez Armijos, Ariel Romero Fernández, Karina Pérez Teruel
Neutrosophic Sets and Systems
No abstract provided.
A Neutrosophic Servqual Model Approach To Study The Quality Of Teaching Support Services At A Technological Institute In Ecuador, Víctor Gustavo Gómez Rodríguez, Abel Stalin Flores Laaz, Noemí Barbara Delgado Álvarez, Alejandro Reigosa Lara, Manuel Roberto Tolozano Benites
A Neutrosophic Servqual Model Approach To Study The Quality Of Teaching Support Services At A Technological Institute In Ecuador, Víctor Gustavo Gómez Rodríguez, Abel Stalin Flores Laaz, Noemí Barbara Delgado Álvarez, Alejandro Reigosa Lara, Manuel Roberto Tolozano Benites
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Perspectives In Healthcare Decision-Making: Navigating Complexity With Ethics, Information, And Collaboration, Alex Gabriel Lara Jacome, Elizabeth Mayorga Aldaz, Miguel Ramos Argilagos, Darvin Manuel Ramírez Guerra
Neutrosophic Perspectives In Healthcare Decision-Making: Navigating Complexity With Ethics, Information, And Collaboration, Alex Gabriel Lara Jacome, Elizabeth Mayorga Aldaz, Miguel Ramos Argilagos, Darvin Manuel Ramírez Guerra
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Interpretation Of Legal Texts And Contracts, Mario Ramiro Aguilar Martínez, Nivela Ortega Emver, Rosa Evelyn Chuga Quemac, Nemis García Arias
Neutrosophic Interpretation Of Legal Texts And Contracts, Mario Ramiro Aguilar Martínez, Nivela Ortega Emver, Rosa Evelyn Chuga Quemac, Nemis García Arias
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Marketing Strategy And Consumer Behavior, Jimena Montes De Oca Sánchez, Myriam Paulina Barreno Sánchez, Miriam Janeth Pantoja Burbano, Osmanys Pérez Peña
Neutrosophic Marketing Strategy And Consumer Behavior, Jimena Montes De Oca Sánchez, Myriam Paulina Barreno Sánchez, Miriam Janeth Pantoja Burbano, Osmanys Pérez Peña
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Analysis Of Group Dynamics And Teamwork, Jeannette Amparito Urrutia Guevara, Edmundo Enrique Pino Andrade, Ned Vito Quevedo Arnaiz, Dante Manuel Macazana Fernández
Neutrosophic Analysis Of Group Dynamics And Teamwork, Jeannette Amparito Urrutia Guevara, Edmundo Enrique Pino Andrade, Ned Vito Quevedo Arnaiz, Dante Manuel Macazana Fernández
Neutrosophic Sets and Systems
No abstract provided.
Neutrosophic Evaluation Of Csr Practices In Ecuadorian Companies: Balancing Sustainability, Ethics, And Impact, Gustavo Alvarez Gómez, Corona Gómez Armijos, Jimena Montes De Oca Sánchez, Dennys Raúl Dupotey Hernández
Neutrosophic Evaluation Of Csr Practices In Ecuadorian Companies: Balancing Sustainability, Ethics, And Impact, Gustavo Alvarez Gómez, Corona Gómez Armijos, Jimena Montes De Oca Sánchez, Dennys Raúl Dupotey Hernández
Neutrosophic Sets and Systems
No abstract provided.
Evaluation Of The Quality Of Care In Nursing Homes, Mónica Bustos Villarreal, Nairovys Gómez Martínez, Roberto Enrique Alvarado Chacón
Evaluation Of The Quality Of Care In Nursing Homes, Mónica Bustos Villarreal, Nairovys Gómez Martínez, Roberto Enrique Alvarado Chacón
Neutrosophic Sets and Systems
No abstract provided.