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Articles 811 - 840 of 29225
Full-Text Articles in Entire DC Network
Interrogation Of The Molecular Mechanisms That Finetune Fcεri Signaling And Mast Cell Outcomes, Derek A. Rinaldi
Interrogation Of The Molecular Mechanisms That Finetune Fcεri Signaling And Mast Cell Outcomes, Derek A. Rinaldi
Biomedical Sciences ETDs
FcεRI is the ITAM receptor primarily responsible for the allergic response and immune hypersensitivity diseases such as asthma. Regulation of the strength of both FcεRI signaling, and the resulting outcomes, is accomplished via a complex array of molecular mechanisms whose interactions remain unclear. Here, I explored how the biophysical properties of antigens, crosstalk between FcεRI and integrin signaling and Arf6-mediated control of trafficking and exocytosis tune mast cell outcomes. I first found significant differences in FcεRI aggregation, phosphorylation and granule secretion after crosslinking with the multivalent antigen DNP-BSA or the small, trivalent antigen DF3. I also revealed a bi-directional, Syk-mediated …
The 2005 Bosnian Law On Defense; A Policy Change Case Study, Gregory D. Vuksich
The 2005 Bosnian Law On Defense; A Policy Change Case Study, Gregory D. Vuksich
Political Science ETDs
The Dayton Peace Accord (DPA) in 1995 ended the civil war in Bosnia and Hercegovina and established a constitution for the newly institutionalizing state. It permitted the three ethnicities – Bosniaks, Croats and Serbs – to retain their wartime armed forces in place under ethnic command, a prerogative the Serbs guarded strenuously. International organizations, however, sought a single, multiethnic military institution for the whole of the country. In 2005, however, the Serbs reversed their opposition and agreed to the international organization preference. This study explores why Bosnia’s Serbian community reversed its earlier and acceded to the creation of a single …
Hsc Connects Newsletter - December 15, 2023, Unm Hsc Communications
Hsc Connects Newsletter - December 15, 2023, Unm Hsc Communications
HSC Connects Newsletters
Weekly newsletter of the UNM Health Sciences Center.
Aleukemic Chronic Myeloid Leukemia Without Neutrophilia And Thrombocytosis: A Report From The Bcr::Abl1 Pathology Group, Daniel Rivera, Wei Cui, Juehua Gao, Deniz Peker, Qian-Yun Zhang, Rajan Dewar, Lianqun Qiu, Sergej Konoplev, Zhihong Hu, Koji Sasaki, Aileen Y. Hu, Shuyu E, Meng Liu, Hong Fang, Wei Wang, Guilin Tang, Jane F Apperley, Andreas Hochhaus, Jorge E. Cortes, Joseph D. Khoury, L Jeffrey Medeiros, Elias Jabbour, Shimin Hu
Aleukemic Chronic Myeloid Leukemia Without Neutrophilia And Thrombocytosis: A Report From The Bcr::Abl1 Pathology Group, Daniel Rivera, Wei Cui, Juehua Gao, Deniz Peker, Qian-Yun Zhang, Rajan Dewar, Lianqun Qiu, Sergej Konoplev, Zhihong Hu, Koji Sasaki, Aileen Y. Hu, Shuyu E, Meng Liu, Hong Fang, Wei Wang, Guilin Tang, Jane F Apperley, Andreas Hochhaus, Jorge E. Cortes, Joseph D. Khoury, L Jeffrey Medeiros, Elias Jabbour, Shimin Hu
Pathology Research and Scholarship
Chronic myeloid leukemia (CML) is characterized by leukocytosis with left-shifted neutrophilia, basophilia, eosinophilia, and variable thrombocytosis. However, extremely rare cases of patients with CML without significant leukocytosis and thrombocytosis (aleukemic phase [ALP] CML, or CML-ALP) have been reported. Due to its rarity and limited awareness, there remains a significant knowledge gap concerning the pathologic diagnosis, disease progression, and optimal patient management and outcomes. In this multi-institutional study, we investigated 31 patients with CML-ALP. Over half (54.8%) of patients had a history of or concurrent hematopoietic or nonhematopoietic malignancies. At time of diagnosis of CML-ALP, approximately 26.7% of patients exhibited neutrophilia, …
A Single C-Terminal Residue Controls Sars-Cov-2 Spike Trafficking And Incorporation Into Vlps, Debajit Dey, Enya Qing, Yanan He, Yihong Chen, Benjamin Jennings, Whitaker Cohn, Suruchi Singh, Lokesh Gakhar, Nicholas J Schnicker, Brian G Pierce, Julian P Whitelegge, Balraj Doray, John Orban, Tom Gallagher, S Saif Hasan
A Single C-Terminal Residue Controls Sars-Cov-2 Spike Trafficking And Incorporation Into Vlps, Debajit Dey, Enya Qing, Yanan He, Yihong Chen, Benjamin Jennings, Whitaker Cohn, Suruchi Singh, Lokesh Gakhar, Nicholas J Schnicker, Brian G Pierce, Julian P Whitelegge, Balraj Doray, John Orban, Tom Gallagher, S Saif Hasan
2020-Current year OA Pubs
The spike (S) protein of SARS-CoV-2 is delivered to the virion assembly site in the ER-Golgi Intermediate Compartment (ERGIC) from both the ER and cis-Golgi in infected cells. However, the relevance and modulatory mechanism of this bidirectional trafficking are unclear. Here, using structure-function analyses, we show that S incorporation into virus-like particles (VLP) and VLP fusogenicity are determined by coatomer-dependent S delivery from the cis-Golgi and restricted by S-coatomer dissociation. Although S mimicry of the host coatomer-binding dibasic motif ensures retrograde trafficking to the ERGIC, avoidance of the host-like C-terminal acidic residue is critical for S-coatomer dissociation and therefore incorporation …
Engaging With ‘Less Affluent’ Communities For Food System Transformation: A Community Food Researcher Model (Foodsequal Project), C. Pettinger, L. Hunt, H. Gardiner, P. Garg, L. Howard, C. Wagstaff
Engaging With ‘Less Affluent’ Communities For Food System Transformation: A Community Food Researcher Model (Foodsequal Project), C. Pettinger, L. Hunt, H. Gardiner, P. Garg, L. Howard, C. Wagstaff
School of Health Professions
The UK food system is distorted by inequalities in access, failing the people most in need, yet it should provide access to safe, nutritious affordable food for all citizens. Dietary patterns are associated with sociodemographic characteristics, with high levels of diet-related disease mortality attributed to poor dietary habits. Disadvantaged UK communities face urgent public health challenges, yet area often treated as powerless recipients of dietary and health initiatives. The need for food system transformation has been illustrated within recent UK government policy drivers and research funding. The Food Systems Equality project1 is a research consortium that aims to ‘co-produce healthy …
Leaf Thermal Regulation Strategies Of Canopy Species Across Four Vegetation Types Along A Temperature And Precipitation Gradient, Yingying Zhou, Nawatbhrist Kitudom, Sophie Fauset, Martijn Slot, Zexin Fan, Jianping Wang, Weiwei Liu, Hua Lin
Leaf Thermal Regulation Strategies Of Canopy Species Across Four Vegetation Types Along A Temperature And Precipitation Gradient, Yingying Zhou, Nawatbhrist Kitudom, Sophie Fauset, Martijn Slot, Zexin Fan, Jianping Wang, Weiwei Liu, Hua Lin
School of Geography, Earth and Environmental Sciences
The ecophysiological processes of leaves are more related to leaf temperature (Tl) than air temperature (Ta). Transpiration and leaf physical traits enable plants to maintain Tl within a thermal range. However, it is challenging to quantitatively study leaf thermal regulation strategies, due to the complex interaction between thermal effects of transpiration and leaf physical traits. We utilized a 3-T method that compares Tl, Ta, and Tn (the temperature of non-transpiring leaves) investigate thermal regulation strategies of dominant canopy species in four vegetation types, including a savanna woodland, a tropical rain forest, a subtropical evergreen broad-leaved forest, and a temperate mixed …
An Overview Of The Cut Flower Industry, Makaylie Langford, Kynda R. Curtis, Melanie Stock
An Overview Of The Cut Flower Industry, Makaylie Langford, Kynda R. Curtis, Melanie Stock
All Current Publications
This fact sheet provides an overview of the cut flower industry. It provides information about traditional and specialty cut flowers, comparing flowers sourced locally in Utah and internationally.
Understanding The Lived Experiences Of Ethnic-Racial Minority Former Foster Youth Who Identify As Queer, Cristian A. Lemus
Understanding The Lived Experiences Of Ethnic-Racial Minority Former Foster Youth Who Identify As Queer, Cristian A. Lemus
Doctoral Dissertations
This qualitative study used Interpretative Phenomenological Analysis to explore the lived experiences and meaning making of former foster youth of color who identify as both ethnic-racial minorities and as either gender or sexual minorities. A total of three participants took part in this study. All participants identified as a former foster youth with at least one foster care placement in the United States, as an ethnic-racial minority, and as a gender or sexual minority. In the lived experiences of the participants three themes, and several subthemes, emerged: identity, cultural prejudice, and power dynamics. The findings supported the hypothesis former foster …
Experiences Of Black American Millennials: A Qualitative Study Of Internalized And Externalized Coping In The Face Of Racial Trauma, Natalia Angelique Giles
Experiences Of Black American Millennials: A Qualitative Study Of Internalized And Externalized Coping In The Face Of Racial Trauma, Natalia Angelique Giles
Doctoral Dissertations
The experiences Black Americans have faced when standing against racial trauma have impacted the Black community for generations. Though previous generations faced overt styles of racism throughout the eras of slavery and Jim Crow, the invalidation and discrimination have remained consistent within the experiences of the Black American millennial (BAM) generation. Current experiences BAMs face are a combination of both overt and covert styles of racism, which increase mental exhaustion, reduce motivation, and leave the individual psychologically defenseless. The purpose of this qualitative study was to examine the experiences of BAMs in the face of racial trauma. This qualitative research …
Validity And Reliability Of The Persian Version Of The Suboptimal Health Status Questionnaire Among University Staff In Iran, Erfan Ayubi, Salman Khazaei, Shiva Borzouei, Ali R. Soltanian, Samereh Ghelichkhani, Fatemeh Karbin, Yuxiang Yan, Manshu Song, Cuihong Tian, Wei Zhang, Jing Sun, Wei Wang
Validity And Reliability Of The Persian Version Of The Suboptimal Health Status Questionnaire Among University Staff In Iran, Erfan Ayubi, Salman Khazaei, Shiva Borzouei, Ali R. Soltanian, Samereh Ghelichkhani, Fatemeh Karbin, Yuxiang Yan, Manshu Song, Cuihong Tian, Wei Zhang, Jing Sun, Wei Wang
Research outputs 2022 to 2026
Background: Suboptimal Health Status Questionnaire-25 (SHSQ-25) is an established tool for measuring a precision health state between health and illness. The present study aims to assess the validity and reliability of a Persian version of SHSQ-25 (P-SHSQ-25) in a university staff Iranian population. Methods: A sample of 316 academic and supporting staff (163 males, age range from 23 to 64 years old) from Hamadan University of Medical Sciences, Hamadan, Iran was recruited in this population-based cross-sectional study with a questionnaire validation from Apri1 to October 2022. Forward-backward translation method was performed for the SHSQ-25 translation from English to Persian. Internal …
Bear Creek Sanctuary: An Urban Grassland, Soheil Zendeh
Bear Creek Sanctuary: An Urban Grassland, Soheil Zendeh
Bird Observer
No abstract provided.
Gleanings: Don’T Say It’S “Just A Rump”, David M. Larson
Gleanings: Don’T Say It’S “Just A Rump”, David M. Larson
Bird Observer
No abstract provided.
Bird Sightings: January/February 2015, Seth Kellogg, Marjorie W. Rines, Robert H. Stymeist
Bird Sightings: January/February 2015, Seth Kellogg, Marjorie W. Rines, Robert H. Stymeist
Bird Observer
No abstract provided.
Birding Orleans County In The Northeast Kingdom Of Vermont, Bob Stymeist, Martha Steele
Birding Orleans County In The Northeast Kingdom Of Vermont, Bob Stymeist, Martha Steele
Bird Observer
No abstract provided.
Fourth Report Of The Maine Bird Records Committee, Trevor B. Persons, Louis R. Bevier, William J. Sheehan, Peter D. Vickery, Christopher A. Bartlett
Fourth Report Of The Maine Bird Records Committee, Trevor B. Persons, Louis R. Bevier, William J. Sheehan, Peter D. Vickery, Christopher A. Bartlett
Bird Observer
No abstract provided.
About The Cover: White-Eyed Vireo, William E. Davis Jr.
About The Cover: White-Eyed Vireo, William E. Davis Jr.
Bird Observer
No abstract provided.
About The Cover: Lark Sparrow, William E. Davis Jr.
About The Cover: Lark Sparrow, William E. Davis Jr.
Bird Observer
No abstract provided.
A Natural And Political History Of Belle Isle Marsh, Barbara Bishop, Soheil Zendeh
A Natural And Political History Of Belle Isle Marsh, Barbara Bishop, Soheil Zendeh
Bird Observer
No abstract provided.
Ernst Mayr: Building On Charles Darwin’S Legacy In The Twentieth Century, William E. Davis Jr.
Ernst Mayr: Building On Charles Darwin’S Legacy In The Twentieth Century, William E. Davis Jr.
Bird Observer
No abstract provided.
About The Cover: Hudsonian Godwit, William E. Davis Jr.
About The Cover: Hudsonian Godwit, William E. Davis Jr.
Bird Observer
No abstract provided.
Alfred Otto Gross, Bowdoin Academic And Renowned Field Ornithologist, William E. Davis Jr.
Alfred Otto Gross, Bowdoin Academic And Renowned Field Ornithologist, William E. Davis Jr.
Bird Observer
No abstract provided.
The Brookline Bird Club: 1913–1945, John Nelson
Glover Morrill Allen: Accomplished Scientist, Teacher, And Fine Human Being, William E. Davis Jr.
Glover Morrill Allen: Accomplished Scientist, Teacher, And Fine Human Being, William E. Davis Jr.
Bird Observer
No abstract provided.
Bird Sightings: November/December 2010, Seth Kellogg, Marjorie W. Rines, Robert H. Stymeist
Bird Sightings: November/December 2010, Seth Kellogg, Marjorie W. Rines, Robert H. Stymeist
Bird Observer
No abstract provided.
Birding The Lakeville Ponds Of Plymouth County, Massachusetts, Jim Sweeney
Birding The Lakeville Ponds Of Plymouth County, Massachusetts, Jim Sweeney
Bird Observer
No abstract provided.
Geezer Birding, John Nelson
First Report Of The Rhode Island Avian Records Committee, Shaibal S. Mitra, Doug Wilson, Robert Emerson, Rachel Farrell, Richard Ferren, Christopher Raithel, Scott Tsagarakis
First Report Of The Rhode Island Avian Records Committee, Shaibal S. Mitra, Doug Wilson, Robert Emerson, Rachel Farrell, Richard Ferren, Christopher Raithel, Scott Tsagarakis
Bird Observer
No abstract provided.
About The Cover: Barn Swallow, William E. Davis Jr.
About The Cover: Barn Swallow, William E. Davis Jr.
Bird Observer
No abstract provided.
Fourteenth Report Of The Massachusetts Avian Records Committee, Marshall J. Iliff, Matthew P. Garvey
Fourteenth Report Of The Massachusetts Avian Records Committee, Marshall J. Iliff, Matthew P. Garvey
Bird Observer
No abstract provided.