Digital Commons Network^™

Revised Draft Final Quarterly Operations And Maintenance Report Butte Treatment Lagoon System – Third Quarter 2022, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Teacher Perceptions On The Sustainability Of Trauma-Informed Practices In A Delaware School, Joy Elaine Campbell

Electronic Theses and Dissertations

The purpose of this qualitative phenomenological study was to explore teacher perceptions about the sustainability of trauma-informed practices implementation in a secondary, public comprehensive school. For the purpose of this study, the researcher examined perceptions of 10 staff members who have knowledge of and experience with implanting trauma-informed practices into their school routine. The findings from this study can be used by teachers, support staff, school leaders, and district leaders to help sustain an institutional application and implementation of trauma-informed care in schools. The implication from this study suggests resources for school staff to successfully sustain trauma-informed care.

The Knowledge And Utilization Of Trauma-Informed Care By Educational And Mental Health Professionals Who Serve Children In A Texas City, Mashelle D. Ancell

Electronic Theses and Dissertations

The purpose of this qualitative descriptive study was to understand the knowledge and utilization of trauma-informed care by professionals serving children within schools, social service agencies, or child therapy in a middle-sized Texas city. Previous studies acknowledged the prevalence of trauma and the need for systemic trauma-informed care in communities. The theoretical framework used to guide this study was attachment theory due to the emphasis on securely attached relationships, which is consistent with trauma-informed care. Data collection methods included an online open-ended questionnaire and semistructured personal interviews. Data analysis was completed using reflexive thematic analysis to develop themes from participant …

Ex Post Facto Study Of The Effect Of Generational Cohort And Employment Tenure On Employee Satisfaction Of United States Federal Employees, Justin Lee Reed

Electronic Theses and Dissertations

Generational differences and the socialization process within the workplace are often seen as opposing theoretical approaches when attempting to explain or understand employee satisfaction. Generational cohort theory asserts that the perceptions and outlooks developed during an individual’s formative years are based on historical events and location, which become instrumental in how they see and interact with the world around them. Social identity theory asserts that exposure and inclusion into a group or organization creates acceptance for the individual and this assists in structuring their outlook. The purpose of this quantitative ex post facto study was to determine if and to …

Athletic Training Preceptor Readiness: From Clinician To Educator, Kaylee Jane Newman

Electronic Theses and Dissertations

This qualitative case study investigated athletic training preceptors’ perceptions of their readiness to teach, assess, and integrate graduate athletic training students into clinical practice. Athletic training education has long been primarily entry-level bachelor programs and has recently transitioned to entry-level master’s programs, with the required transition date for all programs by the fall of 2022. The study used a theoretical framework from Schoening’s nurse educator transition model to understand the factors that influence nurses, and similarly, athletic trainers, to transition from a clinician to an educator. Semistructured interviews of current athletic training preceptors were conducted via Zoom to allow deep …

Perceptions Of School Administrators On The Role Of Support Systems In Attrition Among Principals And Assistant Principals, Karina N. Gonzalez

Electronic Theses and Dissertations

School administrators hold complex, varied, and challenging roles. As literature has suggested, these campus leaders must acquire a vast amount of information and knowledge during their formative years in leadership. Yet, the majority have reported that educational preparation programs do not adequately prepare them for the realities of their roles. Without purposeful, structured guidance, school administrators are left to navigate the complexities of their roles with little support or in isolation, which leads to exhaustion, burnout, and attrition. Attrition results in instability for teachers and students and has a financial impact for school districts. The district of study has experienced …

Long Non-Coding Rna Snhg8 Drives Stress Granule Formation In Tauopathies, Reshma Bhagat, Miguel A Minaya, Arun Renganathan, Muneshwar Mehra, Jacob Marsh, Rita Martinez, Abdallah M Eteleeb, Alissa L Nana, Salvatore Spina, William W Seeley, Lea T Grinberg, Celeste M Karch

2020-Current year OA Pubs

Tauopathies are a heterogenous group of neurodegenerative disorders characterized by tau aggregation in the brain. In a subset of tauopathies, rare mutations in the MAPT gene, which encodes the tau protein, are sufficient to cause disease; however, the events downstream of MAPT mutations are poorly understood. Here, we investigate the role of long non-coding RNAs (lncRNAs), transcripts >200 nucleotides with low/no coding potential that regulate transcription and translation, and their role in tauopathy. Using stem cell derived neurons from patients carrying a MAPT p.P301L, IVS10 + 16, or p.R406W mutation and CRISPR-corrected isogenic controls, we identified transcriptomic changes that occur …

Pigo-Cdg: A Case Study With A New Genotype, Expansion Of The Phenotype, Literature Review, And Nosological Considerations, Rodrigo Tzovenos Starosta, Nino Kerashvili, Cassandra Pruitt, Matthew J. Schultz, Suzanne W Boyer, Eva Morava, Maria Laura Duque Lasio, Dorothy K Grange

2020-Current year OA Pubs

The phosphatidylinositol glycan anchor biosynthesis class O protein (PIGO) enzyme is an important step in the biosynthesis of glycosylphosphatidylinositol (GPI), which is essential for the membrane anchoring of several proteins. Bi-allelic pathogenic variants in

An Educational Program To Improve African American Women’S Knowledge And Self Efficiency In Seeking Treatment For Endometrial Cancer, Lauren Elise Rosenthall

Electronic Theses and Dissertations

In the United States, there is a significant difference in the survival rate for endometrial cancer for African American women when compared to women of other ethnic groups, specifically White women. There is supporting evidence that supports that morbidity and mortality rates for endometrial cancer increase if diagnosed in later stages. There are many contributing factors to a patient receiving an early diagnosis of a disease. One of the key determinants to early diagnosis of endometrial cancer is understanding risk factors, and what symptoms require further evaluation. An educational program was developed to identify knowledge deficits in the African American …

Prospection Of Peptide Inhibitors Of Thrombin From Diverse Origins Using A Machine Learning Pipeline, Nivedha Balakrishnan, Rahul Katkar, Peter V. Pham, Taylor Downey, Prarthna Kashyap, David C. Anastasiu, Anand K. Ramasubramanian

Faculty Research, Scholarly, and Creative Activity

Thrombin is a key enzyme involved in the development and progression of many cardiovascular diseases. Direct thrombin inhibitors (DTIs), with their minimum off-target effects and immediacy of action, have greatly improved the treatment of these diseases. However, the risk of bleeding, pharmacokinetic issues, and thrombotic complications remain major concerns. In an effort to increase the effectiveness of the DTI discovery pipeline, we developed a two-stage machine learning pipeline to identify and rank peptide sequences based on their effective thrombin inhibitory potential. The positive dataset for our model consisted of thrombin inhibitor peptides and their binding affinities (KI) curated from published …

Exploring College Experiences Of Muslim Students At Four-Year Institutions In Colorado: A Narrative Inquiry, Kamal Gamada Ararso

Electronic Theses and Dissertations

In the last two decades, Colorado's number of Muslim Americans (citizens and permanent residents) has substantially increased (Bowen, 2009a; Bowen, 2009b; Mohamed, 2021; Roberts, 2022). This increase is reflected in the growing number of Islamic community centers, emerging Islamic schools, mosques, grocery stores, Muslim cuisines, and the diversity of students in the post-secondary education system (Roberts, 2022). Although centralized data about Muslim college students are hard to find, their presence within the higher education system is well-known. Still, in Colorado, Muslims' religious, racial, cultural, and gendered experiences within the higher education system remained unexplored in the research. Therefore, this exploratory …

Moderate-To-Vigorous Intensity Cycling Exercise Immediately After Visual Learning Enhances Delayed Recognition Memory Performance, Andrew C. Venezia, Lauren R. Weiss, Kristy A. Nielson, J. Carson Smith

Psychology Faculty Research and Publications

A single bout of acute aerobic exercise has been shown to improve long-term memory, though it is unclear if exercise before learning or after learning is optimal for memory enhancement. Although some research has demonstrated that exercise before learning is ideal, investigations have consistently shown that acute arousal post-learning is a powerful memory enhancer. Therefore, the purpose of this investigation was to compare the effects of self-perceived hard cycling before or after learning on recognition memory for emotional and neutral images, and examine the relationship between central noradrenergic activity and memory performance. Seventy-two males and females (18–35 years of age) …

Coordinated Regulation Of Myonuclear Dna Methylation, Mrna, And Mirna Levels Associates With The Metabolic Response To Rapid Synergist Ablation-Induced Skeletal Muscle Hypertrophy In Female Mice, Ahmed Ismaeel, Nicholas T. Thomas, Mariah Mccashland, Sebastian Edman, Johanna T. Lanner, Vandré C. Figueiredo, Christopher S. Fry, John J. Mccarthy, Yuan Wen, Kevin A. Murach, Ferdinand Von Walden

Health, Human Performance and Recreation Faculty Publications and Presentations

The central dogma of molecular biology dictates the general flow of molecular information from DNA that leads to a functional cellular outcome. In skeletal muscle fibers, the extent to which global myonuclear transcriptional alterations, accounting for epigenetic and post-transcriptional influences, contribute to an adaptive stress response is not clearly defined. In this investigation, we leveraged an integrated analysis of the myonucleus-specific DNA methylome and transcriptome, as well as myonuclear small RNA profiling to molecularly define the early phase of skeletal muscle fiber hypertrophy. The analysis of myonucleus-specific mature microRNA and other small RNA species provides new directions for exploring muscle …

Effect Of 24-H Blood Pressure Dysregulations And Reduced Ocular Perfusion Pressure In Open-Angle Glaucoma Progression, Jesus D. Melgarejo, Jan V. Eijgen, Dongmei Wei, Gladys E. Maestre, Lama A. Al-Aswad, Chia-Te Liao, Luis J. Mena, Thomas Vanassche, Stefan Janssens, Peter Verhamme

School of Medicine Publications

Background:

Low ocular perfusion pressure (OPP), which depends on the mean arterial pressure (MAP) and intraocular pressure (IOP), is associated with glaucoma. We studied 24-h MAP dysregulations and OPP in relation to the progression of glaucoma damage.

Methods:

We retrospectively analyzed 155 normal-tension glaucoma (NTG) and 110 primary open-angle glaucoma (POAG) patients aged 18 years old followed at the University Hospital Leuven with repeated visual field tests (n = 7000 measures, including both eyes) who underwent 24-h ambulatory blood pressure monitoring. Twenty-four-hour MAP dysregulations were variability independent of the mean (VIM), and the five lowest dips in MAP readings …

Subungual Squamous Cell Carcinoma Leading To Arm Amputation, Ovidiu V. Fabian, Emilia Maria Pătruţ, Mădălina Șteţca, Radu Mircea Galasiu, Vlad Zolog, Adriana Zolog, Iacob Domşa, Ioan Șimon, Anca Mihailov, Olga Hilda Orăşan, Flaviu Mureşan

Journal of Mind and Medical Sciences

Although rare, subungual carcinoma is the most common malignant nail tumor. The symptomatology is not characteristic, being very similar to that of other nail and periungual diseases. For this reason, early diagnosis is usually established by performing a biopsy. With appropriate treatment, subungual carcinoma usually has a favorable prognosis. Metastatic cases are rarely encountered, but they usually have a poor therapeutic result. This article presents the case of a patient with subungual carcinoma (diagnosed by histopathological exam), initially treated by amputation of the distal and middle phalanges of the fourth finger. Two years after the operation, a recurrence in the …

Giant Renal Cell Carcinoma In A Patient With Ipsilateral Lower Limb Hypertrophic Lichen Planus; Case Report And Literature Review, Silvia Popescu, Dumitru Peța, Zoltan Janos Kövér, Dumitru Toma, Ioan-Teodor Cristea, Mihaela Anca Popescu, Oana-Denisa Bălălău, Romina-Marina Sima, Gabriel-Petre Gorecki, Călin Giurcăneanu

Journal of Mind and Medical Sciences

Renal cell carcinoma is the most common type of primary urogenital cancer, usually resistant to radiotherapy and chemotherapy. Hypertrophic lichen planus is an inflammatory dermatosis characterized by the presence of papulosquamous and intensely pruritic lesions. The association of these two conditions is unusual, being reported in the specialized literature only in a few rare cases with the onset of lichenoid lesions after patients have undergone various forms of treatment. The case of a 62-year-old male patient who was admitted for severe abdominal pain due to a giant renal tumor associated with a hypertrophic plaque located on the anterior part of …

Prevalence Of Comorbidities And Survival Analysis Of Covid-19 Patients – An Observational Study From A Tertiary Healthcare Center In North West Romania, Mihaela Simona Popoviciu, Lorena Paduraru, Roxana Adriana Stoica, Anca Pantea Stoian, Claudiu Teodorescu, Simona Cavalu

Journal of Mind and Medical Sciences

Objectives. The experience accumulated in the last two years shows that the prevention of COVID-19 in people with comorbidities (protective measures, vaccination, etc.) still remains a public health priority. In this context, the aim of our study was to perform a retrospective, observational study in order to assess the time-to-death and risk factors of mortality among COVID-19 patients. Materials and Methods. The study was conducted on 177 patients admitted to Oradea Emergency County Hospital, Bihor, Romania, between October and December 2021. Inclusion criteria were patients over 18 years positive for COVID-19 in upper respiratory tract samples using real-time PCR test. …

Revascularization Impact: Quality Of Life Enhancement In Chronic Limb-Threatening Ischemia, Cristian Traian Paius, Vlad Denis Constantin, Alexandru Carap, Andrei Tarus, Grigore Tinica

Journal of Mind and Medical Sciences

Introduction. Globally, over 230 million people have peripheral artery disease, often undiagnosed, leading to chronic limb-threatening ischemia. Revascularization is vital for preventing amputation and improving quality of life. While specific questionnaires for severe ischemia are lacking, the SF-36 questionnaire is widely used to assess quality of life, with variations like SF-12 and SF-8 for larger cohorts. Objectives. Our aim was to assess how different lower limb revascularization methods affect the postoperative quality of life in patients with chronic limb-threatening ischemia. Methods. This study was conducted at the St. Pantelimon Emergency Hospital of Bucharest, Romania. It included 166 adult patients with …

Follow-Up Care After Metabolic Surgery – A Prospective Study In The North-Eastern Region Of Romania, Sorina Boariu, Ana Maria Scutariu, Adrian Cureniuc, Anamaria Meuca, Roxana Adriana Stoica, Anca Mihaela Pantea Stoian, Delia Reurean Pintilei

Journal of Mind and Medical Sciences

Background. Anti-obesity therapeutic strategies are continuously evolving. Bariatric procedures or metabolic surgery are among the most effective and long-lasting therapies for obesity and its complications. Our objective was to investigate the clinical and biological evolution after metabolic surgery in a group of patients from North-Eastern Romania and to evaluate a nutritional intervention plan for this population. Materials and Methods. Our clinic surveyed 50 patients who received nutritional counselling before and after bariatric surgery. The patient's weight loss, metabolic markers, and lifestyle changes from January to December 2021 were recorded. SPSS Statistics v.18 was used for statistical analyses. Results and Discussions. …

The Role Of Inflammation In Age-Related Macular Degeneration, Diana Florina Tricorache, Ana Maria Dascalu, Crenguta Serboiu, Anca Bobirca, Dragos Cretoiu, Dan Bratu, Corneliu Tudor, Laura Carina Tribus

Journal of Mind and Medical Sciences

Age-related macular degeneration (AMD) is a complex, chronic, and progressive disease which affects the macular area, being one of the leading causes of irreversible vision loss worldwide. Specific alterations of retinal structure occur at the macular level, which regarding its severity can range from the presence of drusen to the development of geographic atrophy or choroidal neovascularization. AMD has long been considered a degenerative disease, but new studies highlight the role of inflammation present both in the atrophic form and in the exudative form. The present review is based on comprehensive research on PubMed and Web of Science databases, and …

Sentinel Node Biopsy For Personalized Breast Cancer Management; Advances And Controversies, Rahim Al Moushaly, Daniel Ion, Octavian Andronic, Bogdan Socea, Alexandru Cosmin Palcau, Dan Nicolae Paduraru

Journal of Mind and Medical Sciences

Sentinel lymph node biopsy (SLNB) has become the gold standard for axillary lymph node staging, providing valuable prognostic information while minimizing complications compared to axillary lymph node dissection. However, there are ongoing debates and controversies surrounding SLNB in specific cases. Studies have explored the use of SLNB in neoadjuvant chemotherapy, emphasizing the need for customized therapy decisions. Factors such as age, tumor characteristics, and treatment response influence the selection of SLNB or axillary lymph node dissection. Additionally, the presence of extranodal extension, micrometastases, and isolated tumor cells has been evaluated to determine the need for lymphadenectomy. The importance of accurate …

Diabetes Mellitus: Interdisciplinary Medical, Surgical And Psychological Therapeutic Approach, Bogdan Socea, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Cristian Balalau, Tiberiu Ștefăniță Tenea-Cojan, Doina Andrada Mihai, Ioana Paunica

Journal of Mind and Medical Sciences

Diabetes mellitus is a complex and widespread metabolic disease, having extremely complex implications (biological, psychological, social) for patients. Understanding the pathophysiology of diabetes (majorly influenced by various factors such as genetic predisposition, age, lifestyle choices, etc.) is essential for the prevention of this condition and the establishment of effective treatment strategies. The latest and relevant literature data related to the epidemiology, pathophysiology, and treatment of diabetes are presented, after an exhaustive review of the articles published on this topic and indexed in the WOS, PubMed, Scopus and Google Scholar databases. Preventing or delaying the onset of diabetes can be achieved …

From Covid-19 To Long Covid; The Forms Of The Neurological Manifestations, Sana Ahuja, Sufian Zaheer

Journal of Mind and Medical Sciences

Ever since the SARS-CoV-2 infection was declared a global pandemic in 2020, numerous multisystemic manifestations have been discovered. The COVID-19 is known to cause a wide spectrum of neurological symptoms like fatigue, headache, brain fog, stroke, smell and taste disorders, encephalopathy and neurodegenerative disorders. The neurological manifestations are more prevalent in the post-COVID syndrome or long COVID. The National Institute for Health and Care Excellence and WHO defined Ongoing Symptomatic COVID as 4-12 weeks post infection and post COVID-19 syndrome as persistence of symptoms beyond 12 weeks. So far there are limited data available regarding the pathophysiology of neurological symptoms …

Gastric Cancer; Actualities And Perspectives Of Early Diagnosis And Targeted Therapy, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Anca Dumitriu, Stana Paunica, Cristian Balalau, Stefăniță Tenea Cojan, Dragos Epistatu, Vlad Denis Constantin

Journal of Mind and Medical Sciences

Gastric cancer is an extremely aggressive form of malignancy that, if left untreated, is life-threatening. Improved survival rates depend on early detection of the disease, as well as on the combination of different forms of treatment (surgery, chemotherapy, radiotherapy, immunotherapy, etc.). Screening methods have brought real benefit in early detection of malignancies, but many cases are still diagnosed at advanced stages. The current study is a review related to actualities and perspectives of early diagnosis and targeted therapy of gastric cancer. After an extensive review of the literature, epidemiological, diagnostic and treatment data are presented. The open surgical approach is …

Barrett's Esophagus As A Premalignant Condition; Medical And Surgical Therapeutic Management, Vlad Denis Constantin, Adrian Silaghi, Laura Florentina Rebegea, Stana Paunica, Anca Silvia Dumitriu, Doina Andrada Mihai, Ioana Paunica, Dragos Epistatu

Journal of Mind and Medical Sciences

Barrett's esophagus (BE) represents a special clinical entity, which may have reduced symptoms, but an increased potential for malignant degeneration. The factors that lead to the appearance of Barrett's esophagus are multiple, the most important being gastro-esophageal reflux, as well as smoking and obesity. BE occurs as a result of damage of the esophageal mucosa, caused by acid/basic gastroesophageal reflux and resulting in the transformation of the epithelium from squamous to intestinal type. The diagnosis of BE is primarily based on endoscopic examination. This method has not only a diagnostic role, but also a therapeutic one through the minimally invasive …

Addressing Racism In Medicine With Community-Based Doula Services For Black Mothers, A Narrative Review Of The Literature And Historical Perspective, Brianna Roberts Canales, Emily Sloane

Marshall Journal of Medicine

No abstract provided.

It’S All About Fishing: Robert Ellis Jenkins (1940-2023) And His Life Among Freshwater Fishes Of Virginia And The Redhorse Suckers, Eric J. Hilton

Southeastern Fishes Council Proceedings

Robert (Bob) Ellis Jenkins passed away in Salem, Virginia, on Wednesday, July 12, 2023. Bob was born February 9, 1940 in Brooklyn, New York. As a child, Bob took an early interest in natural history, and was a particularly avid fisherman. He attended Roanoke College (Salem, VA) as an undergraduate and entered into a Masters degree program at Virginia Tech (Blacksburg, VA), only to leave before finishing for a position at the NOAA Systematics Lab based at the Smithsonian Institution’s National Museum of Natural History. He eventually became faculty at his alma mater, Roanoke College, where he would spend virtually …

Synaptic Proteins Involved In Reward-Based Plasticity, Cameron Martinez, Christian Wesselborg, Hey-Kyoung Lee Ph.D

Trick to the Treat of Internships and Research

My research focused on synaptic proteins involved in reward-based plasticity. More specifically, my aim sought to expand brain tissue in order to resolve the problem of distinguishing between synapses. This process involved using different biological assays.

Clear Vision Center Of South Florida Biol 4990 - Independent Study In Biology, Bita Sabripour

Trick to the Treat of Internships and Research

During my internship at Clear Vision Center of South Florida, I had the opportunity to shadow and work alongside Dr. Bita Sabripour to examine and provide eye care services to patients. I learned various clinical practices including taking patients' history, working the front desk, taking inventory, placing orders, selling frames, assisting patients, and keeping the office running. In addition, I ran the clinic's social media platforms and was in charge of communication with various manufacturers and sales representatives. I also volunteered with the associated nonprofit organization, See Your Future, which provides free eye care and services to the underprivileged and …

Dietary Interventions During Chemotherapy Treatment: A Systematic Review Of Feasibility, Safety, And Efficacy, Shalet James, Alexie Oppermann, Amber S. Kleckner

Trick to the Treat of Internships and Research

Chemotherapy is a mainstay for cancer treatment. However, chemotherapy is associated with side effects that can significantly limit a person's physical and cognitive functioning, both reducing quality of life and leading to dose reductions of life-saving treatment. Dietary interventions may help manage and reduce the side effects of chemotherapy through biological and psychological mechanisms. While there is preliminary evidence supporting the importance of nutrition in cancer care, current guidelines are vague except for minimum calorie and protein intake to prevent malnutrition. The aim of this systematic review is to evaluate the feasibility, safety, and efficacy of dietary interventions on health …