Digital Commons Network^™

Antimicrobial Resistance In Streptococcus Pneumoniae: A Retrospective Analysis Of Emerging Trends In The United Arab Emirates From 2010 To 2021, Abiola Senok, Jens Thomsen, Najiba M. Abdulrazzaq, The Uae Amr Surveillance Consortium, Godfred Antony Menezes, Carole Ayoub Moubareck, Dean Everett

All Works

Although pneumococcal conjugate vaccines (PCV) have been effective in reducing the burden of Streptococcus pneumoniae infections, there is a paucity of data on the relationship with antimicrobial resistance (AMR) trends in the Arabian Gulf region. This study was carried out to assess S. pneumoniae resistance trends in the United Arab Emirates (UAE) where PCV-13 vaccination was introduced in 2011. Retrospective analysis of S. pneumoniae demographic and microbiological data collected as part of the national AMR surveillance program from 2010 to 2021 was carried out. A survey of reporting sites and hand searching of annual reports of local health authorities was …

An Integrated Computational Biology Approach Defines The Crucial Role Of Trip13 In Pancreatic Cancer, Swati Dhasmana, Anupam Dhasmana, Stella Rios, Iris A. Enriquez-Perez, Sheema Khan, Farrukh Afaq, Shafiul Haque, Upender Manne, Murali M. Yallapu, Subhash C. Chauhan

School of Medicine Publications

Highlights

• Integrative computational biology techniques are holistic approaches in cancer discovery by exploring multiple levels of convolution in biological systems.

• Pancreatic cancer is expected that by 2030, it will become the 2nd leading cause of cancer related deaths in the United States alone.•

• For the first time, the role and patholgenic events of TRIP13 in PanCa have been discussed.

• This study elucidates the role of TRIP13 on molecular level, as a specific signal for early events of pancreatic cancer, enhancing patient prognosis, and boosting targeted therapies in clinical settings.

• This study has potential to enrich the existing biomarker panel for …

Interrogating Households In Anticipation Of Disasters: The Feminization Of Preparedness, Chika Watanabe, Celie Hanson

Critical Disaster Studies

It is now a maxim among scholars and policy-makers alike that disaster preparedness needs to involve community-based approaches in order to be effective. These include preparedness strategies in the household. But how do disaster preparedness policies and public discourses define “the household” in the first place? In this article, we explore how particular gendered notions of the household are reproduced in disaster preparedness policies and activities in Japan and the UK. Drawing on historical and cross-cultural analyses, we suggest that household preparedness efforts place the burden of labor on people coded as women—a phenomenon we call “the feminization of preparedness.” …

Understanding Marsh Elevation And Accretion Processes And Vulnerability To Rising Sea Levels Across Climatic And Geomorphic Gradients In California, Usa, Karen M. Thorne, Mckenna L. Bristow, Lyndsay L. Rankin, Katya E. Kovalenko, Justine A. Neville, Chase M. Freeman, Glenn R. Guntenspergen

State & Federal Reports and Publications

Tidal marshes build elevations by below- and aboveground organic and mineral soil processes. Marsh elevation and accre- tion data can be used to determine if marshes are keeping pace with sea-level rise. Using a network of 54 deep rod surface elevation tables with paired feldspar marker horizon plots, we tracked elevation and accretion trends across 16 marshes in California, USA. All sites had overall positive gains across years that included severe drought conditions and extreme rain events. Marsh elevation relative to tidal datum (z*) was the key predictor for elevation and accretion rates, with higher change rates at lower z* …

Port Hamilton Refining And Transportation Lllp V. Epa

2023 Decisions

Agency

The "Nonministerial" Exception, Athanasius G. Sirilla

Notre Dame Law Review

In 2014, Charlotte Catholic High School declined to continue Lonnie Billard’s employment as a substitute drama teacher after he publicly announced, via Facebook, that he and his same-sex partner were getting civilly married. Billard sued the school in the Western District of North Carolina for unlawful employment discrimination under Title VII of the Civil Rights Act due to his sexual orientation. The district court granted summary judgment in favor of Billard. The court first held that the high school’s actions could constitute unlawful sex discrimination in light of the Supreme Court’s ruling in Bostock v. Clayton County. The district court …

Jackfish (Caranx Lugubris) Neurocranium, Lauren Groves, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from 9 cm total length (TL) Jackfish, Caranx lugubris, collected from Ideal Market on September 18th, by Lauren Groves

Regulation Of Regeneration In Arabidopsis Thaliana, Md Khairul Islam, Sai Teja Mummadi, Sanzhen Liu, Hairong Wei

Michigan Tech Publications

We employed several algorithms with high efficacy to analyze the public transcriptomic data, aiming to identify key transcription factors (TFs) that regulate regeneration in Arabidopsis thaliana. Initially, we utilized CollaborativeNet, also known as TF-Cluster, to construct a collaborative network of all TFs, which was subsequently decomposed into many subnetworks using the Triple-Link and Compound Spring Embedder (CoSE) algorithms. Functional analysis of these subnetworks led to the identification of nine subnetworks closely associated with regeneration. We further applied principal component analysis and gene ontology (GO) enrichment analysis to reduce the subnetworks from nine to three, namely subnetworks 1, 12, and 17. …

Brha, Kevin Rafferty, Briana K. Zaffiro, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Skull from Broad-winged Hawk (Buteo platypterus).

2023-11-22 To Pay Or Not To Pay: Seattle Public Transit, Bridget Lawrence

The Spectator Online

No abstract provided.

N6-Methyladenosine-Mediated Overexpression Of Long Noncoding Rna Adamts9-As2 Triggers Neuroblastoma Differentiation Via Regulating Lin28b/Let-7/Mycn Signaling, Yun Liu, Jun Zhang, Fang Cao, Xiaobao Dong, Jie Li, Yanna Cao, Zhanglin Li, Yan Guo, Jie Yan, Yuanyuan Liu, Qiang Zhao

Faculty, Staff and Student Publications

Neuroblastomas have shed light on the differentiation disorder that is associated with spontaneous regression or differentiation in the same tumor at the same time. Long noncoding RNAs (lncRNAs) actively participate in a broad spectrum of biological processes. However, the detailed molecular mechanisms underlying lncRNA regulation of differentiation in neuroblastomas remain largely unknown. Here, we sequenced clinical samples of ganglioneuroma, ganglioneuroblastoma, and neuroblastoma. We compared transcription profiles of neuroblastoma cells, ganglion cells, and intermediate state cells; verified the profiles in a retinoic acid-induced cell differentiation model and clinical samples; and screened out the lncRNA ADAMTS9 antisense RNA 2 (ADAMTS9-AS2), which contributed …

The Impact Of Environmental Factors And Management On The Fitness Of Carlina Acaulis Subsp. Caulescens (Lam.) Schübl. Et G. Martens In Mountain Mesic Meadows, Daniel Pruchniewicz, Ȃngela Lomba, Ludwik Żołnierz, Agnieszka Dradrach, João Pradinho Honrado

Turkish Journal of Botany

The stemless carline thistle (Carlina acaulis subsp. caulescens) is a plant species commonly found at lower altitudes in the Central European mountains. Although it is still relatively frequent in the area, there has been a decrease in its numbers in the last decades. This research aims to determine the impact of the management of mountain mesic meadows and habitat factors on the morphometric variability of C. acaulis and species composition patterns of accompanying vegetation. The study was carried out in the central part of the Sudetes Mountains (SW Poland) on a network of 42 plots randomly established within mesic grasslands. …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Ethnobotany Of Medicinal Plants Used In Dermatology In Türkiye: A Review, Serpi̇l Demi̇rci̇ Kayiran, Meryem Parlak, Di̇dem Yilmaz Oral

Turkish Journal of Botany

Medicinal plants are increasingly used to treat skin diseases and as cosmetics. Türkiye has a rich diversity of medicinal flora, and patients have a choice of ethnomedicines to manage various dermatology problems. This comprehensive review aims to summarize the primary information available on the dermatological properties of medicinal plants in Türkiye and provide a baseline for the detection of new plant species having efficacy against skin conditions. In this review, clinical and experimental data were researched using relevant search terms in scientific literature databases like PubMed, Web of Science, Google Scholar, ScienceDirect, Scopus, EBSCO, ProQuest, Cochrane Library, and HighWire Press. …

A Comprehensive Ethnobotanical Survey Of Medicinal Plants For 80 Villages In Trabzon (Türkiye), Sila Ozlem Sener, Kami̇l Çoşkunçelebi̇, Sali̇h Terzi̇oğlu, Aleyna Nalçaoğlu, Tuğçe Peli̇n Gençkaya, Ufuk Özgen, Merve Yüzbaşioğlu Baran

Turkish Journal of Botany

The current study targeted to perform qualitative and quantitative analysis of medicinal plant taxa used in folk medicine in Trabzon. Due to its historical significance, diversity of plant species, and hosting a wide range of cultures, the Turkish city of Trabzon has significant ethnobotanical potential. Ethnobotanical data including family name, scientific name, local name, used parts, therapeutic uses, preparation methods, administration routes, and cited locations were gathered by face-to-face interviews with 645 participants mostly over 50 years old. The quantitative analyses were executed by the determination of frequency values of citation (FC), use value (UV), fidelity level (FL), and informant …

Biochar Influences On Phytochemical Composition And Expression Genes Of Curly Kale At Different Treatment Times, Joyce Dedei Anteh, Esraa Almugrabi, Antonina Mostyakova, Olga Timofeeva

Turkish Journal of Botany

his study examined the effect of biochar application to the soil at different times on the phytochemical composition (phenolic compounds, carotenoids, vitamin C, sugars, proteins, MDA, and antioxidant activity) and expression of HCT, F3’H and CHS genes (which are involved in the accumulation of phenolic compounds) in cabbage kale (Brassica oleracea L. var. acephala). Biochar was prepared from chicken manure, using the method of rapid pyrolysis at a temperature of 400 °C. The retention time at the maximum temperature was 4 h, and the heating rate was 10 °C min–1. The biochar fertilizer was applied to 5–7 day-old kale seedlings …

A New Species Of Parasola Section Conopileae (Psathyrellaceae) From Pakistan, Zaman Khan, Muhammad Awais Arshad, Abdul Rehman Niazi, Abdul Nasir Khalid

Turkish Journal of Botany

The genus Parasola is sparsely documented in Pakistan with almost all of its reports from lowlands or northern areas of the country. In this study, we describe a new species, Parasola cinnamomescens, from the Thal Desert, a subtropical region located in Punjab Province, Pakistan. Evidence from morphology and DNA sequence data encompassing the internal transcribed spacer (ITS1-5.8S-ITS2 = ITS) and D1/D2 domain of the large subunit of nuclear ribosomal DNA (28S) reveals that this species is divergent from all previously known species and confirms its placement in Parasola sect. Conopileae. It is recognized by convex to hemispherical or broadly conical …

Influence Of Rootstock Age And Gibberellin On The Survival Rate Of Clove (Syzygium Aromaticum L. Merr. & Perr.) Grafting, Ireng Darwati, Rudi Suryadi, Nurliani Bermawie, Octivia Trisilawati, Devi Rusmin, Sri Wahyuni, Siswanto Siswanto, R Vitri Garvita

Turkish Journal of Botany

Clove (Syzygium aromaticum) is a cross-pollinated crop with significant genetic variation in planting materials derived from seeds. Vegetative propagation through grafting is a valuable strategy to achieve genetically identical characteristics in progeny. This study investigates the influence of rootstock age and hormone (gibberellin) treatments on the grafting union and survival rate of top clove grafting under greenhouse conditions. The experiments followed a randomized block design with three replications, each containing 10 samples, and involving two factors: rootstock age (4, 6, and 8 weeks old) and gibberellin (GA3 ) concentrations (0 and 1 mg L–1). The variables observed include success percentage, …

Pollen Morphology Of Scabiosa L. And Lomelosia Raf. (Caprifoliaceae) Taxa In Türkiye, Ahmet Aksoy, Bayram Atasagun

Turkish Journal of Botany

Pollen morphology of 34 taxa belonging to genera Scabiosa and Lomelosia were investigated using a light microscope (LM) and scanning electron microscopy (SEM). Pollen grains of Scabiosa and Lomelosia taxa are tricolpate and triporate, respectively. Pollen shapes vary from oblate to prolate. The exine surface ornamentation can be divided into five types, namely echinate, echinatemicroechinate, echinate-gemmate, echinate-microechinate/gemmate and microechinate-gemmate. Pollen grain sizes were classified as very large in three species of Lomelosia and large in the rest. Statistical analyses revealed some quantitative morphological features, such as equatorial axes, L (polar view amb), and t (apocolpium) as the primary characters for …

Northern Red Snapper (Lutjanus Campechnus) Neurocranium, Ajani K. Saldana, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from 7.5 cm total length (TL) 37 cm Lutjanus campechanus (Northern Red Snapper), collected from Mango Tree Supermarket in September 2023 by Ajani Saldana

Blsk 3d Scan, Kevin Rafferty, Briana K. Zaffiro, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Skull from Black Skimmer (Rhnchops niger)

Genome-Wide Identification Of Qtls Associated With Iron Deficiency Tolerance In Soybean Reveals Gata12 As The Integrator Of Iron Signaling In Roots, Amir Maqbool, Ahmet Şahi̇n, Allah Bakhsh, Emre Aksoy

Turkish Journal of Botany

Iron (Fe) is an essential micronutrient required for plant growth and development. However, its deficiency causes substantial yield losses, particularly in alkaline soils. Soybean (Glycine max) serves as an ideal model to study Fe deficiency chlorosis (IDC) due to its inefficient Fe uptake from the soil. Although the quantitative trait loci (QTL) associated with IDC tolerance were determined in soybean, the specific genes within these QTL regions remain unidentified. In this study, it was aimed to identify and analyze the expression levels of genes present in IDC-responsive soybean QTL under Fe deficiency. Through this investigation, 6593 genes were identified within …

Tidal Bed Stress Asymmetry And Sediment Transport In Estuaries, Austin Scott Hudson

Dissertations and Theses

Rivers and estuaries provide numerous ecological, economic, and cultural resources. The value of these resources is greatly influenced by sediment transport processes, which can be affected by human activities and climate variability. A key driver of sediment transport in tidal rivers and estuaries is tidal asymmetry of velocity and bed stress, which can manifest from both non-linear tidal interactions and linear interactions among astronomical tidal constituents.

In this study, an analytical framework is developed to examine and describe the dynamics of bed stress asymmetry in semidiurnal, diurnal, and mixed-tide estuaries (Chapter 1). While tidal velocity asymmetry has been previously analyzed, …

Beta-Carbonic Anhydrase Gene Expression Levels Change Depending On The Drought Severity In Both The Leaves And Roots Of Arabidopsis Thaliana, Sertan Çevi̇k, Oğuzhan Kurt, Ayşi̇n Güzel Değer, Ferit Kocaçinar, Rıza Bi̇nzet

Turkish Journal of Botany

In this study, it was aimed to determine the relationship between β carbonic anhydrase (βCA) gene expression levels and drought stress severity. For this purpose, the expression levels of six βCA genes in the roots and leaves of Arabidopsis thaliana were investigated under mild, moderate, and severe drought conditions. In addition, changes in the biomass, leaf water content, photosynthetic efficiency, CA enzyme activity, free proline content, and lipid peroxidation were also determined. The results showed that all of the β CA gene expression levels and CA enzyme activity increased in the leaf under mild drought conditions; however, the expression levels …

Engineering Virtuous Health Habits Using Emotion And Neurocognition: Flexibility For Lifestyle Optimization And Weight Management (Even Flow), Patrick J. Smith, Heather E. Whitson, Rhonda M. Merwin, C. Virginia O'Hayer, Timothy J. Strauman

Department of Psychiatry and Human Behavior Faculty Papers

Interventions to preserve functional independence in older adults are critically needed to optimize 'successful aging' among the large and increasing population of older adults in the United States. For most aging adults, the management of chronic diseases is the most common and impactful risk factor for loss of functional independence. Chronic disease management inherently involves the learning and adaptation of new behaviors, such as adopting or modifying physical activity habits and managing weight. Despite the importance of chronic disease management in older adults, vanishingly few individuals optimally manage their health behavior in the service of chronic disease stabilization to preserve …

Trichoderma Indica: A New Species In The Longibrachiatum Clade From Western Ghats, India, Ajay Lagashetti, Sanjay Singh, Paras Nath Singh

Turkish Journal of Botany

Trichoderma is a hyperdiverse genus that comprises species showing a wide range of applications. In this study, we have found an isolate of the genus Trichoderma from a soil sample collected from Vetal Hill, Pune, Maharashtra State, India. The isolate was found to be morphologically distinct compared to other isolates of the Longibrachiatum clade showing longer phialides and shorter conidia. Moreover, a phylogenetic analysis based on combined sequence data of the second-largest nuclear RNA polymerase subunit (rpb2), and the translation elongation factor 1-α (tef1-α) confirmed the uniqueness of the present isolate, showing an independent branch supported by strong bootstrap values …

Glial Cell Adhesion Molecule (Glialcam) Determines Proliferative Versus Invasive Cell States In Glioblastoma, Arpan De, John M Lattier, John E Morales, Jack R Kelly, Xiaofeng Zheng, Zhihua Chen, Sumod Sebastian, Zahra Nassiri Toosi, Jason T Huse, Frederick F Lang, Joseph H Mccarty

Faculty, Staff and Student Publications

The malignant brain cancer glioblastoma (GBM) contains groups of highly invasive cells that drive tumor progression as well as recurrence after surgery and chemotherapy. The molecular mechanisms that enable these GBM cells to exit the primary mass and disperse throughout the brain remain largely unknown. Here we report using human tumor specimens and primary spheroids from male and female patients that glial cell adhesion molecule (GlialCAM), which has normal roles in brain astrocytes and is mutated in the developmental brain disorder megalencephalic leukoencephalopathy with subcortical cysts (MLC), is differentially expressed in subpopulations of GBM cells. High levels of GlialCAM promote …

Prospective Relationship Between Co-Rumination And Depressive Symptoms In Early Adolescence: Brooding Rumination As A Mechanism, Katherine S. Benjamin

Clinical Psychology Dissertations

Adolescence is a developmental period during which there is a significant increase in depressive symptoms. Both interpersonal and intrapersonal emotion regulation strategies, including co-rumination and rumination, contribute to the development of depressive symptoms. However, there has been relatively little research investigating the connections between co-rumination and rumination and their associations with depression. Theories of depression, such as interpersonal theories and Response Styles Theory suggest that both relational processes and the ways in which an individual responds internally may promote and maintain depressive symptoms. The current study examined whether brooding rumination serves as the mechanism explaining the relationship between co-rumination and …

The Implications Of Ferroptosis In Antibiotic Resistance, Marysol Hohl

Senior Honors Theses

Bacterial infections in the United States are becoming increasingly resistant to existing antibiotic treatments. Due to projected increases in resistance and the recent decrease in novel antibacterials, experts have determined that the United States is in the “post-antibiotic era.” The scientific community has failed to resolve resistance despite the continual discovery of new antibiotic compounds. In the past decade, a novel form of cell death called ferroptosis has been implicated in antibiotic treatment by employing the use of nanotechnology. This literature review will describe the problem of bacterial resistance and demonstrate how current research is pioneering a new age of …

Dopamine, Norepinephrine And Serotonin Participate Differently In Methylphenidate Action In Concomitant Behavioral And Ventral Tegmental Area, Locus Coeruleus And Dorsal Raphe Neuronal Study In Young Rats, Cruz Reyes-Vasquez, Zachary Jones, Bin Tang, Nachum Dafny

Faculty, Staff and Student Publications

Methylphenidate (MPD), known as Ritalin, is a psychostimulant used to treat children, adults, and the elderly. MPD exerts its effects through increasing concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT) in the synaptic cleft. Concomitant behavioral and neuronal recording from the ventral tegmental area (VTA), locus coeruleus (LC), and from the dorsal raphe (DR) nucleus, which are the sources of DA, NE, and 5-HT to the mesocorticolimbic circuit, were investigated following acute and repetitive (chronic) saline, 0.6, 2.5, or 10.0 mg/kg MPD. Animals received daily saline or MPD administration on experimental days 1 to 6 (ED1–6), followed by a …