Digital Commons Network^™

Expanding Delivery Of And Access To Evidence-Based Comprehensive Hiv/Srh Services Among Men Who Have Sex With Men (Msm) And Transgender Persons In Nigeria, Anita Fernandez, Adebola A. Adedimeji, Waimar Tun, Ann Gottert, Julie Pulerwitz

Sexual and Reproductive Health, Rights, and Choices

The goals of this project were to: i) increase comprehensive HIV service delivery among MSM, transgender women, and their sexual partners, ii) build the capacity of a local NGO to function as a one-stop-shop for HIV and STI services, and iii) build evidence around the “hub and spokes” service delivery model, how to best reach transgender populations, and to pilot an intervention intended to promote mental health and reduce intersectional, internalized stigma experienced by sexual and gender minorities (both living with HIV and at risk of HIV acquisition). The project implemented a “hub and spokes” model of service provision of …

A Systematic Review To Study The Global Patterns And Policies Of Hiv Harm Reduction Programs And Their Impact Among People Who Inject Drugs, Noura Shaltout, Rania Soliman, Lamia Refaey, Rim Ghazal, Mirna Atteya, Nahla Elmedany

Papers, Posters, and Presentations

Aim: This study aims to provide an updated estimate of HIV prevalence among people who inject drugs (PWID) globally, as well as investigate different policies and methods for applying harm reduction. This article focuses on the two major and the most frequently used harm reduction techniques, Syringe-Service Programs (SSPs) and Opioid Agonist Therapy (OAT). Methods: A comprehensive systematic review was undertaken across multiple international databases during the period of (August-December 2021). For studies conducted before 2005, we used data from a previous published systematic review. Thirty-six studies were included, including studies that had performed HIV testing and had a confirmed …

Effect Of Poor Menstrual Health On Uti Diagnosis, Michelle Muturi

Pitzer Senior Theses

Urinary Tract infections (UTIs) are microbial invasions of the urinary tract because of abnormal pathogen growth. They have short term symptoms like abdominal pain, fever and urinary frequency. Khayelitsha is a township that has a population of 2.4 million, 52% of which are women. This area is shaped by poor governance in South Africa that exacerbated medical issues due to a lack of resources. With lack of sanitary pad accessibility and knowledge of proper hygiene practices during the menstrual cycle, women are getting infected with UTIs 2-3 times a year. With an increase in antimicrobial resistance patterns, areas like Khayelistsha …

Radioactive, Internal Colonialism: The Uranium Industry’S Historic And Current Impact On The Navajo Nation, Sophie Arens

Pitzer Senior Theses

The United States withheld information pertaining to the health problems associated with nuclear power, allowing uranium to be extracted, processed, and stored in the Southwest of the United States and more specifically the Navajo Nation. With this, many Diné people who had previously worked in the mines or lived within close vicinity to facilities developed various types of illnesses. This thesis argues that the development of nuclear energy in the United States is a form of radioactive, internal colonialism and that the current waste facility located in Carlsbad, New Mexico is furthering this history into the present day. This thesis …

Health Behavior And Outlooks In An Altered Microbial Diversity: Changes In Parental Attitudes On ‘Building Immunity’ Throughout The Covid-19 Pandemic, Jennifer Vidal

Pitzer Senior Theses

The Covid-19 Pandemic in a short amount of time put into action disease control measures. Current literature has sought to address the long-term effects of sanitization efforts and social isolation on the diversity of the microbiome and the future of infectious diseases. Microbes – microorganisms such as bacteria, protozoa, algae, fungi, and viruses – inhabit the natural environment and human microbiome with our immune system, playing an essential role in immune regulation. The interplay between humans and microbes forms early immune development that has impacted parents’ attitudes toward microbes shown through their participation in Covid-19 preventative health practices. Using the …

“If It Ain’T One Thing, It’S Another”: Black Lgbtq Students And Their Experiences With School Discipline And Punishment, Quentin Jenkins

Pitzer Senior Theses

School officials have disproportionately applied disciplinary policies and exclusionary practices to Black and LGBTQ youth, causing those students to be negatively sanctioned. Characterized by instruments of surveillance, metal detectors, and the presence of law enforcement, schools in the United States have significantly exacerbated the negative experiences these children have within educational spaces. Schools foster “prison-like” environments and subject Black LGBTQ youth to hyper-surveillance, thus increasing their likelihood of coming in contact with the juvenile justice system. Grounded in BlackCrit and Quare theory, this paper analyzes how the coupled intersecting identities of Blackness and Queerness lead Black LGBTQ youth to have …

My Backyard Garden, Hezekiah Smithstein

Pitzer Senior Theses

This thesis follows my attempts to create a new relationship with the land outside my house, through transforming my weed-choked backyard into a native plant garden. Through styles of memoir, essay, and literary journalism, I examine what it means to take care of the outdoor home, as a human family part of an urban ecosystem. This project explores ideas surrounding people and plants, the effects on a space of actions and interactions both past and present, and brings into conversation different ideas and philosophies from homeowner to ecologist, city park to indigenous author, that shape the way we think and …

An Analysis On How Housing Status Influences The Gut-Brain-Axis For Populations In And Around The Skid Row Area Of Los Angeles, California, Mauricio Guzman

Pitzer Senior Theses

Over recent years, the “microbiota-gut-brain axis” (MGBA) has garnered significant attention in the scientific community. Specifically, perturbations of the MGBA via stress and dietary intake have been linked to a wide-range of diseases including gastrointestinal diseases, metabolic diseases, mood disorders, and cognitive diseases. However, most studies have been solely conducted on mice models and have yet to consider the more complex, intricate systems that impact the human body. In addition, researchers have yet to consider the populations who may be most susceptible to chronic stress and negative dietary outcomes. Drawing from the fields of medical sociology, non-invasive human biology, and …

Development Of A Leadership Mindset Scale, Nathan M. Kangas, V. Krishna Kumar, Betsy J. Moore, Christopher A. Flickinger, Jennifer L. Barnett

Psychology Student Work

The purpose of the study was to construct a Leadership Mindset Scale (LMS) and to assess its reliability and construct validity. Participants were 100 employees in a variety of leadership and non-leadership positions at various organizations in three states. An item and factor analysis on the 13 LMS items led to a scale with 11 items (Cronbach α = .80). A Principal Axis Factor analysis with Promax rotation suggested three factors: Leadership Mindset Teachability (LMS-T), a belief in leadership teachability; Leadership Mindset Improvability (LMS-I), a belief in leadership improvability over time; and Leadership Mindset Predictability (LMS-P), a belief that leadership …

Silica Particles Convert Thiol-Containing Molecules To Disulfides, Yangjie Li, Kurt W. Kolasinski, Richard N. Zare

Chemistry Faculty Publications

Synthetic amorphous silica is a common food additive and a popular cosmetic ingredient. Mesoporous silica particles are also widely studied for their potential use in drug delivery and imaging applications because of their unique properties, such as tunable pore sizes, large surfaces areas, and assumed biocompatibility. Such a nanomaterial, when consisting of pure silicon dioxide, is generally considered to be chemically inert, but in this study, we showed that oxidation yields for different compounds were facilitated by simply incubating aqueous solutions with pure silica particles. Three thiol-containing molecules, L-cysteine, glutathione, and D-penicillamine, were studied separately, and it was found that …

Homopurine Guanine-Rich Sequences In Complex With N-Methyl Mesoporphyrin Ix Form Parallel G-Quadruplex Dimers And Display A Unique Symmetry Tetrad, Ming Ye, Erin V. Chen, Shawn H. Pfeil, Kailey N. Martin, Tamanaa Atrafi, Sara Yun, Zahara Martinez, Liliya A. Yatsunyk

Physics & Engineering Faculty Publications

DNA can fold into G-quadruplexes (GQs), non-canonical secondary structures formed by pi-pi stacking of G-tet-rads. GQs are important in many biological processes, which makes them promising therapeutic targets. We identified a 42-nucleotide long, purine-only G-rich sequence from human genome, which contains eight G- stretches connected by A and AAAA loops. We divided this sequence into five unique segments, four guanine stretches each, named GA1-5. In order to investigate the role of adenines in GQ structure formation, we per-formed biophysical and X-ray crystallographic studies of GA1-5 and their complexes with a highly selective GQ ligand, N-methyl mesoporphyrin IX (NMM). Our data …

Observing The Relationship Between Physical Activity, Overall Health, Anxiety, And Sleep, Brianna Chicas

Honors Undergraduate Theses

College students' mental health has been researched for some time. In particular, the correlation between physical activity and mental health symptoms has been researched. The study examines the relationship between physical activity and anxiety, sleep, and overall health. College undergraduate students at the University of Central Florida took an online survey that measured all of these variables. A Pearson's correlation coefficient was used to assess correlations. Positive correlations were found between anxiety and sleep, anxiety and social desirability, sleep and social desirability, and strength training and vigorous physical activity. Negative correlations were found between overall health and physical activity, overall …

Horizontal Foot Speed During Submaximal And Maximal Running, Kenneth P. Clark, Laurence J. Ryan, Christopher R. Meng, David J. Stearne

Kinesiology Faculty Publications

Horizontal foot speed is fundamental for running synchronization and stability, and may also be important for sprinting performance. In this investigation, we quantified the following during steady-speed running: (a) peak forward foot speed during the swing phase, (b) backward foot speed at touchdown, and (c) ground speed difference (GSD), i.e., the difference between forward running speed and backward foot speed at touchdown. We hypothesized that forward and backward foot speed would be significantly and positively correlated with top speed, and that GSD would be significantly and negatively correlated with top speed. Participants (20 male, 20 female) completed 40-m submaximal and …

Male Pornography Viewers' Perceptions Of Asian Women, Caitlyn M. Koerner

Honors Undergraduate Theses

Objectification and sexual aggression are common themes in pornography. However, there are only a handful of quantitative studies that examine the role of race in pornography that included Asian women, a population that has been fetishized extensively and historically portrayed as hypersexual in mainstream media. There were also no studies on the self-reported attitudes of viewers around this topic. 96 male university students took a survey measuring the frequency and perception of their pornography use, their acceptance of sexual aggression myths, their objectification of Asian women, and their propensity to agree with microaggressions about Asian women. Results indicated that while …

The Effects Of Kangaroo Care On The Stress Levels Of Parents In The Nicu, Niyati Sishodia

Honors Undergraduate Theses

Background: Parents of NICU patients have high stress levels compared to other populations, which negatively impact their mental health. The kangaroo care (KC) method has been used for its numerous benefits for infants, but not as widely studied for its impacts on parental stress. The purpose of this integrative literature review is to examine and synthesize the existing evidence regarding kangaroo care and its impact on the stress levels of NICU parents.

Methods: A literature search was conducted utilizing CINAHL Plus with Full Text, MEDLINE, and APA PsychInfo databases to identify relevant articles. Articles were included if they were published …

Acute Myocardial Infarction Among People Living With Hiv: Comparing Immunological And Virological Control By Hispanic Ethnicity Of The All Of Us Research Program Participants, Eugenio Reina

Honors Undergraduate Theses

In the United States, individuals of Hispanic ethnicity receive disproportionately lower-quality healthcare. These healthcare disparities exacerbate unequal access to quality healthcare services, including disparities in cardiovascular disease (CVD) and human immunodeficiency virus (HIV) care. Research on the role of ethnicity on the CVD outcomes of people living with HIV (PLWH) has been limited. We hypothesize that immunological (CD4+ cell count) and virological (HIV viral load) control may play a role in the development of acute myocardial infarction (AMI) among PLWH, and that Hispanic ethnicity may worsen these outcomes.

To verify our hypotheses, we conducted a retrospective cross-sectional study to investigate …

Social Determinants Of Chronic Kidney Disease In The Black American Community: A Systematic Review, Addea Coleman

Honors Undergraduate Theses

This systematic review aims to examine the relationship between the social determinants of health that significantly impact the prevalence and progression of chronic kidney disease (CKD) amongst Black Americans. The Black American population has the highest prevalence of CKD in the United States, while concurrently possessing prominent genetic risk factors for this chronic disease. The social determinants: healthcare quality and access (extended to account for health behaviors), social and community context, and economic stability were specifically assessed in this review. Key terms were utilized to search electronic databases PubMed and Web of Science, which yielded 470 unduplicated articles. Twenty-nine articles …

Reconstructing Oral Health In Pre-Hispanic Peru: Antemortem Tooth Loss And Caries As Possible Evidence Of Dental Care In Túcume, Peru, Amy Rodriguez

Honors Undergraduate Theses

Evidence of dental manipulation dates back several centuries and is identifiable through modification of human skeletal remains and the remnants of ancient tools. The act of caring for dental patients, on the other hand, is much more abstract and not as explicitly documented throughout history. Through the analysis of skeletal dentition of individuals from Pre-Hispanic Peru, this research aims to understand possible early forms of dental care practices. Specifically, by calculating the frequency of common dental pathology, I evaluated the possible presence of dental care in Túcume, Peru, during the Late Intermediate Period (1000 to 1500 AD) and what this …

The Impact Of Telemedicine On Patient-Provider Communication At A University Student Health Center, Venkata Naga Sreelalitapriya Duvuuri

Honors Undergraduate Theses

Effective patient-provider communication (PPC) involves conveying sufficient information to a patient such that the treatment is agreed upon and implemented accurately. Furthermore, a patient must feel adequately involved in the treatment process. With the advent of the COVID-19 pandemic, many clinical visits were shifted online. Although telemedicine was successful in meeting pandemic-specific goals, such as lowering personal contact, it changes the communicative context. Both patients and providers get less input from body language (nonverbal communication) and rely more on verbal communication. Furthermore, the number of telemedicine visits conducted remains elevated over pre-pandemic levels. Much of what is known about effective …

Role Of Endoplasmic Reticulum Stress Response In Parainfluenza Virus Acute To Persistent Infections, Lauren L. Abbitt

Honors Undergraduate Theses

Persistent viral infections are a major health concern, with persistently infected (PI) cells being a source of continued shedding of virus and generation of viral mutants. Here, we hypothesized that cells persistently infected with the enveloped virus parainfluenza virus 5 (PIV5) would show altered expression of endoplasmic reticulum (ER) stress proteins and increased resistance to death caused by drug-induced ER stress. To test this, lysates of mock-infected, PIV5 acute-infected, and PIV5 PI human lung A549 cells were collected and levels of ER stress proteins were compared. Western blotting revealed that immunoglobulin heavy chain binding protein (BiP/GRP78) was present in higher …

Using Wastewater-Based Epidemiology To Study Chlamydia Occurrence On A College Campus, Jessie E. Chin Quee

Honors Undergraduate Theses

Chlamydia is a sexually transmitted disease caused by Chlamydia trachomatis, commonly affecting sexually active college-aged adults. Presently, opportunistic testing, self-testing, and information campaigns are methods to screen vulnerable populations and raise awareness about chlamydia. Chlamydia remains underdiagnosed and undertested due to a lack of participation by individuals who may have been exposed to it. Wastewater-based epidemiology is a rising biomonitoring tool that detects the presence of disease- and drug-specific biomarkers in a community's wastewater. In this study, wastewater-based epidemiology was used to detect the presence of C. trachomatis on the University of Central Florida campus. Wastewater samples were collected …

Trends In Antibiotic Susceptibility Of Staphylococcus Aureus Isolates In A Pediatric Hospital: An Analysis Of The Impact Of The Sars-Cov-2 Pandemic, Juan Miguel S. Gonzalez Rivero

Honors Undergraduate Theses

Infections caused by the organism Staphylococcus aureus are one of the most common causes for community-associated and healthcare-acquired infections (HAI). Isolates of this bacterium found within the healthcare setting often demonstrate a higher prevalence of antibiotic resistance making these infections difficult to treat. Historically, considerable focus has been placed on methicillin-resistant S. aureus (MRSA), which are strains resistant to β-lactam antibiotics like penicillin, oxacillin and cephalosporins; however, methicillin-sensitive (MSSA) strains may also possess resistance to several first-line antibiotics. Resistance to antibiotics can be acquired through horizontal gene transfer (HGT) by means of mobile genetic elements or by random DNA mutations …

Beauty In Sorority Life: An Anthropological Analysis Of Beauty Ideals And Body Modification, Delaney C. Mclinden

Honors Undergraduate Theses

Sororities are social organizations on college campuses categorized by selective membership and exclusive social events for active members. This research focuses on how sorority members' ideas about beauty relate to their appearance management behaviors in order to gauge how sorority culture contributes to their understanding of physical beauty. Ethnographic

data collection took place at a university in the southeastern United States. I conducted 17 semi- structured interviews with members of different sororities and participant observation at sorority

recruitment events. There's a common thread that connects every interview: beauty and appearance carry importance. Sorority culture encourages women to put "effort" into …

Testicular Cancer And Firefighters: An Umbrella Review, Andre Naguib Guirguis

Honors Undergraduate Theses

Purpose: The relationship between testicular cancer and working as a firefighter has been a relatively brushed off scope of concentration until recent years and recent developments in hopes of presenting new protocols and better guidelines to screen for testicular cancer in this occupation. The purpose of this study was to perform a scoping review to present the current data concerning testicular cancer and its association to the occupation of firefighters.

Methods: PubMed as a data base was used and articles concerning firefighters and testicular cancer were found and screened for eligibility with respect to the kind of study and the …

The Significance Of Art Education: Creating A Digital Classroom Advocating Art Education, Keri K. O'Connell

Honors Undergraduate Theses

Art programs have always been essential to education; they have provided students with a safe place to express themselves and make risk-free choices. However, due to budget cuts to the public school systems, art education is in jeopardy. The impact of the budget cuts on art education is widespread and has reduced student access to the arts and lowered the quality of the art education programs within our public school system. Schools can only provide students with the necessary resources, such as art supplies, technology, and professional development for art educators, with adequate funding. When schools are not receiving adequate …

Granular Jamming: Stiffness Vs Pressure And Organ Palpation Devices, Christopher H. Quach

Honors Undergraduate Theses

The intent of this thesis it to find a correlation between the stiffness of granular jammed particles and the pressure of the vacuum initiating the jamming force. Currently, granular jamming is being used to create palpation simulators for physicians to practice feeling the variety of stiffnesses of organs when healthy or ill. Because granular jamming allows for variable stiffness of any shape, it is an apt phenomenon to simulate the change of rigidity organs like the liver undergoes when diseased. For physicians to correctly identify how stiff the organ must be when using these palpation simulators, there needs to be …

Measuring Brain Activity Using Fnirs During Discomfort Mitigation With Vr Meditation, Jordan Sammarco

Honors Undergraduate Theses

Pain perception can be drastically affected by external factors in the surrounding environment. Previous studies relying on subjective ratings of pain have shown that guided meditations supplemented by virtual reality (VR) can reduce the perception of pain more successfully than the audio alone. The research question for this study was: How does the efficacy of meditation as a means of pain mitigation differ with and without the application of VR? To answer this question, we used fNIRS to visualize changes in the dorsolateral prefrontal cortex (DLPFC), which has been shown to play a role in the larger pain matrix in …

How Mental Health Impacts The Relationship Between Aesthetics, Perceived Usefulness, And The Intention To Follow Self-Help Social Media Accounts, Quang Hong Phuoc Thai

Honors Undergraduate Theses

Mental health self-help accounts on social media often provide tips and strategies for individuals struggling with mental health difficulties to improve mental health outcomes. As mental health poses a public health concern that causes economic and physical problems worldwide, this self-help approach offers a potential solution to help millions of people at risk. In accordance with Technology Acceptance Models, how useful an individual finds a social media account should predict their intent to follow such accounts. Additionally, since social media accounts are highly visual content-driven, aesthetics may be a significant driver of intent to follow social media accounts. The present …

Silver Doped Nanoceria (Agcnp) Integrated Silk Scaffold For Chronic Wound Healing, Architha K. Venkatesan

Honors Undergraduate Theses

Chronic wound healing can be seriously impeded by the formation of biofilms, infections, peri-wound edema, hematoma, osteomyelitis, and the formation of reactive oxidative species (ROS). We hypothesize that a scaffold created from Silver-Doped Nanoceria (AgCNP) embedding silk can be beneficial to aid the wound healing process, inhibit inflammation and prevent microorganisms from forming a biofilm over the wound. Current wound healing methods such as intradermal injections are not advantageous to use since they can cause unwanted responses elsewhere in the body other than the wound site. Silk, however, has a positive impact on the wound healing effect and can be …

Perceptions Of Music Performance Anxiety Throughout The Covid-19 Pandemic And Their Predictors, Caroline E. Villacis

Honors Undergraduate Theses

Performance anxiety affects individuals across many fields, from sports to medicine to music. Research in the area of Music Performance Anxiety (MPA) has been of particular importance to instrumental and vocal soloists and ensemble members for several decades. Throughout the COVID-19 pandemic, many musicians have been required to change the format and location of their performances. These adjustments, as well as musicians' existing unique characteristics and life experiences, may have impacted their experience of MPA. The purpose of this study was to examine the impact of the COVID-19 pandemic and other factors on MPA. Participants (N = 251) were …