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Towards Generalization Of Deep Learning-Based Plant Disease Identification Under Controlled And Field Conditions, Aanis Ahmad, Aly El Gamal, Dharmendra Saraswat

Purdue University Libraries Open Access Publishing Fund

Identifying corn diseases under field conditions is crucial for implementing effective disease management systems. Deep learning (DL)-based plant disease identification using deep neural networks (DNN) has been successfully implemented in recent years. Recent work suggests DL models trained on lab-acquired image data do not generalize to similar accuracy levels for identifying diseases in the field. Additionally, most studies have not evaluated the generalizability of DL models for identifying plant diseases from various datasets and diverse imaging conditions. This study evaluates how well DL models generalize across different datasets and environmental conditions for identifying plant diseases using five datasets consisting of …

Diel Activity Patterns Of Vector Mosquito Species In The Urban Environment: Implications For Vector Control Strategies, André Barretto B. Wilke, Adequate Mhlanga, Allisandra G. Kummer, Chalmers Vasquez, Maday Moreno, William D. Petrie, Art Rodriguez, Christopher Vitek, Gabriel L. Hamer, John-Paul Mutebi, Marco Ajelli

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Mathematical models have been widely used to study the population dynamics of mosquitoes as well as to test and validate the effectiveness of arbovirus outbreak responses and mosquito control strategies. The objective of this study is to assess the diel activity of mosquitoes in Miami-Dade, Florida, and Brownsville, Texas, the most affected areas during the Zika outbreak in 2016–2017, and to evaluate the effectiveness of simulated adulticide treatments on local mosquito populations. To assess variations in the diel activity patterns, mosquitoes were collected hourly for 96 hours once a month from May through November 2019 in Miami-Dade County, Florida, and …

Montana Kaimin, January 26, 2023, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Spleen Tyrosine Kinase/Fms-Like Tyrosine Kinase-3 Inhibition In Relapsed/Refractory B-Cell Lymphoma, Including Diffuse Large B-Cell Lymphoma: Updated Data With Mivavotinib (Tak-659/Cb-659), Leo I Gordon, Reem Karmali, Jason B Kaplan, Rakesh Popat, Howard A Burris, Silvia Ferrari, Sumit Madan, Manish R Patel, Giuseppe Gritti, Dima El-Sharkawi, F Ian Chau, John Radford, Jaime Pérez De Oteyza, Pier Luigi Zinzani, Swaminathan P Iyer, William Townsend, Harry Miao, Igor Proscurshim, Shining Wang, Shilpi Katyayan, Ying Yuan, Jiaxi Zhu, Kate Stumpo, Yaping Shou, Cecilia Carpio, Francesc Bosch

Faculty, Staff and Student Publications

We report an updated analysis from a phase I study of the spleen tyrosine kinase (SYK) and FMS-like tyrosine kinase 3 inhibitor mivavotinib, presenting data for the overall cohort of lymphoma patients, and the subgroup of patients with diffuse large B-cell lymphoma (DLBCL; including an expanded cohort not included in the initial report). Patients with relapsed/refractory lymphoma for which no standard treatment was available received mivavotinib 60-120 mg once daily in 28-day cycles until disease progression/unacceptable toxicity. A total of 124 patients with lymphoma, including 89 with DLBCL, were enrolled. Overall response rates (ORR) in response-evaluable patients were 45% (43/95) …

Construction And Characterization Of Functional Ftsa Sandwich Fusions For Studies Of Ftsa Localization And Dynamics During Escherichia Coli Cell Division, Todd A Cameron, William Margolin

Faculty, Staff and Student Publications

FtsA, a homolog of actin, is essential for cell division of Escherichia coli and is widely conserved among many bacteria. FtsA helps to tether polymers of the bacterial tubulin homolog FtsZ to the cytoplasmic membrane as part of the cytokinetic Z ring. GFP fusions to FtsA have illuminated FtsA’s localization in live E. coli, but these fusions have not been fully functional and required the presence of the native FtsA. Here, we characterize “sandwich” fusions of E. coli FtsA to either mCherry or msfGFP that are functional for cell division and exhibit fluorescent rings at midcell that persist throughout …

Temporal Sequence And Relationships Between Sleep Disorders, Mental Disorders And Traumatic Brain Injury In Deployed Military Members, Pamela Herbig Wall

Dissertations

U.S. military members are often forward deployed to austere environments where they are exposed to environmental, mental, and physiological stressors that can negatively affect their wellbeing and readiness for service. These service members are at high risk for developing sleep disorders, mental disorders, and traumatic brain injury (TBI) that may produce functional disability and further erode mission readiness. While there is ample evidence on distinct relationships between these three clusters of disorders, relatively few studies examine all three in a military and/or veteran population. Health care providers in the United States Military need information about these complex interactions in order …

The Student Movement Volume 107 Issue 13: We've Got The Spirit: Students Celebrate Dr. Luxton, Nora Martin, Grace No, Gloria Oh, Nathaniel Reid, Solana Campbell, Skylor Stark, Andrew Francis, Christon Arthur, Abigail Kim, Rachel Ingram-Clay, Alexander Navarro, Abby Shim, Lexie Dunham, Alexander J. Hess

The Student Movement v. 107 (2022-2023)

HUMANS

Best of Bon Appetit, Nora Martin

Interview with the Dean of Lamson and Meier Halls, Interviewed by: Grace No

The Joy of Japan, Interviewed by: Gloria Oh

ARTS & ENTERTAINMENT

A Creation Adventure, Nathaniel Reid

Currently: Velma, Solana Campbell

Suite Dreams for Sweet Dreams, Skylor Stark

Where do I Find God? Part II, Anonymous

NEWS

AUSA Celebrates 100 Years of Student-Led Action, Andrew Francis

Response to "A House Divided" Story, Christon Arthur, Provost

Where's the Harm in True Crime?. Abigail Kim

IDEAS

Redefining Free Agency in Sports, Andrew Francis

Flying Cars of 2030, Rachel Ingram-Clay

The Spooky Nature of …

Midweek Memo, Georgia Southern University

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College Of Education News, Georgia Southern University

College of Education: News & Publications (2003-2023)

• Amanda Townley, Ph.D. elected president of the National Association of Biology Teachers (NABT)

A Broad Characterization Of Glycogen Storage Disease Iv Patients: A Clinical, Genetic, And Histopathological Study, Matheus Vernet Machado Bressan Wilke, Bibiana Mello De Oliveira, Rodrigo Tzovenos Starosta, Marwan Shinawi, Liang Lu, Mai He, Yamin Ma, Janis Stoll, Carolina Fischinger Moura De Souza, Ana Cecilia Menezes De Siqueira, Sandra Maria Gonçalves Vieira, Carlos Thadeu Cerski, Lilia Farret Refosco, Ida Vanessa Doederlein Schwartz

2020-Current year OA Pubs

Glycogen storage disease type IV (GSD IV) is an ultra-rare autosomal recessive disease caused by variants in the

A Data-Driven Approach To Construct A Molecular Map Of Trypanosoma Cruzi To Identify Drugs And Vaccine Targets, Swarsat Kaushik Nath, Preeti Pankajakshan, Trapti Sharma, Priya Kumari, Sweety Shinde, Nikita Garg, Kartavya Mathur, Nevidita Arambam, Divyank Harjani, Manpriya Raj, Garwit Kwatra, Sayantan Venkatesh, Alakto Choudhoury, Saima Bano, Prashansa Tayal, Mahek Sharan, Ruchika Arora, Ulrich Strych, Peter J Hotez, Maria Elena Bottazzi, Kamal Rawal

Faculty, Staff and Students Publications

Chagas disease (CD) is endemic in large parts of Central and South America, as well as in Texas and the southern regions of the United States. Successful parasites, such as the causative agent of CD, Trypanosoma cruzi have adapted to specific hosts during their phylogenesis. In this work, we have assembled an interactive network of the complex relations that occur between molecules within T. cruzi. An expert curation strategy was combined with a text-mining approach to screen 10,234 full-length research articles and over 200,000 abstracts relevant to T. cruzi. We obtained a scale-free network consisting of 1055 nodes …

Supplementing Glycine And N-Acetylcysteine (Glynac) In Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, And Aging Hallmarks: A Randomized Clinical Trial, Premranjan Kumar, Chun Liu, James Suliburk, Jean W Hsu, Raja Muthupillai, Farook Jahoor, Charles G Minard, George E Taffet, Rajagopal V Sekhar

Faculty, Staff and Students Publications

BACKGROUND: Elevated oxidative stress (OxS), mitochondrial dysfunction, and hallmarks of aging are identified as key contributors to aging, but improving/reversing these defects in older adults (OA) is challenging. In prior studies, we identified that deficiency of the intracellular antioxidant glutathione (GSH) could play a role and reported that supplementing GlyNAC (combination of glycine and N-acetylcysteine [NAC]) in aged mice improved GSH deficiency, OxS, mitochondrial fatty-acid oxidation (MFO), and insulin resistance (IR). To test whether GlyNAC supplementation in OA could improve GSH deficiency, OxS, mitochondrial dysfunction, IR, physical function, and aging hallmarks, we conducted a placebo-controlled randomized clinical trial.

METHODS: Twenty-four …

A Statistical Analysis Of The Change In Age Distribution Of Spawning Hatchery Salmon, Rachel Macaulay, Emily Barrett, Grace Penunuri, Eli E. Goldwyn

Spora: A Journal of Biomathematics

Declines in salmon sizes have been reported primarily as a result of younger maturation rates. This change in age distribution poses serious threats to salmon-dependent peoples and ecological systems. We perform a statistical analysis to examine the change in age structure of spawning Alaskan chum salmon Oncorhynchus keta and Chinook salmon O. tshawytscha using 30 years of hatchery data. To highlight the impacts of this change, we investigate the average number of fry/smolt that each age of spawning chum/Chinook salmon produce. Our findings demonstrate an increase in younger hatchery salmon populations returning to spawn, and fewer amounts of fry produced …

We Are ... Marshall, January 25, 2023, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

A Happy Lie, Nina Collin

Between the Species

I recently went to a zoo. Wild animals living in confinement with one single purpose: to entertain. When contemplating the concept of a zoo it will become surreal, I promise.

The Current - Volume 33 Issue 4, Nova Southeastern University

Student Newspapers

No abstract provided.

Identity And Community In Digital Culture, Jeffrey H. Mahan

Consensus

No abstract provided.

Gender Identities Outside Of The Binary Existed In Ancient Rome, Samuel Cash

Research on Capitol Hill

Transgender individuals are erased from the historical narrative due to little definitive evidence of their existence in language, literature, or the archaeological record. Items like clothing, textiles, and wigs, which distinguished them from cisgender people, are largely lost to time. However, one way that we can view gender nonconformity is through art. This presentation analyzes the use of androgyny and gender non-conformity in Greco-Roman marble statues, focusing on Apollo. Although he is biologically male, Apollo is known for being effeminate and gender non-conforming. His physical appearance contributes to his feminine attributes, including his androgynous body structure, hairstyle, and clothing. This …

Developing Cancer Treatments With A One-Two Punch Of A Metal And Carbon Monoxide, Joel Ashton

Research on Capitol Hill

Carbon monoxide (CO) has unique therapeutic properties including anti-cancer effects. Flavonols such as 3-hydroxyflavone can release CO upon exposure to visible light. Gallium(III) also has anti-cancer properties and can replace Fe(III) in biological processes. This research was focused on synthesizing a family of complexes with gallium(III) bound to 3-hydroxyflavone and similar ligands which can hopefully combine the anti-cancer properties of both gallium and CO. These complexes follow a simple synthesis and the flavonols are easily modified to optimize their properties. Several of these complexes have been made with varying degrees of solubility. Each of these complexes have been confirmed to …

Is Feeding Algae To Lab- Grown Chicken The Future Of Agriculture?, Elise Barton, Melanie Mills, Britton Porter, Elizabeth Walker

Research on Capitol Hill

The goal of this ongoing research is to develop a more cost-effective process for culturing cells to produce synthetic or lab grown meat. Cellular agriculture is an emerging technology with potential to have a smaller energy footprint and decrease in land used for livestock compared to traditional meat production. Cellular agriculture will allow Utah to experience continued population growth without hampering the meat production of the state. However, currently the cost of producing synthetic meat is a constraint for expanding production and availability. This project is focused on testing various combinations of hydrolysates to determine a cost-effective alternative to current …

Behavioral Strategies Of Social Relationship Formation And Competition Among Adolescent And Adult Male Chimpanzees At Kanyawara, Kibale National Park, Uganda, Drew K. Enigk

Anthropology ETDs

Adolescence is a unique life stage in which individuals are reproductively mature but have not yet attained their full adult body size. In chimpanzees, which live in multimale-multifemale groups, this age period presents a challenge for males. Namely, adolescent males lack the physical strength to compete effectively with adult males for mating opportunities. In the following chapters, we seek to answer whether adolescent male chimpanzees exhibit behavior typical of highly competitive adults but with less success, or whether they pursue alternative behavioral tactics to largely avoid competition until they are fully grown. We utilize both long-term data spanning over two …

January 25, 2023 (Vol. 107, No. 17), Daily Eastern News

Daily Eastern News: 2022-2023

No abstract provided.

Development Of Potent Nanosized Carbonic Anhydrase Inhibitor For Targeted Therapy Of Hypoxic Solid Tumors, Ekram Hany Mohamed, Wagdy M. Eldehna,, Mahmoud A. El Hassab, Nahla A. Abdelshafi,

Pharmacy

Overexpression of two carbonic anhydrase (CA) isoforms, CA IX and XII, in several hypoxic solid tumors provides an extracellular hypoxic microenvironment, interferes with extra- and intracellular pH regulation, thus favoring hypoxic tumor cell survival, proliferation and metastasis. In the current study, a selective inhibitor for human CA isoforms IX and XII (isatin-bearing sulfonamide, WEG-104), was incorporated into nanosized spherical niosomes at high encapsulation efficiency to allow for an enhanced and sustained antitumor activity. In vivo, administration of WEG-104 that is either free (10 mg/kg) or loaded into niosomes (5 mg/kg) into a mice model of Ehrlich ascites solid tumor resulted …

Polyethyleneimine Shell Nucleic Acid Nanostructures From Gold Nanoparticle Template For Chemotherapeutic Drug Delivery, Brendan Guy Rucci

Theses and Dissertations

The next generation of anticancer agents will emerge from rationally designed nanostructured materials. This work involved the synthesis and characterization of novel hollow DNA-conjugated gold nanoparticles (DNA-AuNPs) for controlled drug delivery. Polyethyleneimine (PEI) was bound to citrate-capped AuNPs, forming polymer-shell nanoparticles. Dissolution of the gold core via iodine formed hollow core polymeric nanoparticles (HCPPs) and a high density of DNA (85 molecules/particle) containing daunorubicin was conjugated. Particles were spherical with an average diameter of 105.7±17.3 nm and zeta potential of 20.4±3.54 mV. We hypothesize the DNA backbone electrostatically condensed to the primary amines on the surface of the particle toroidally, …

Contesting Narratives: Sibling Relations As Political Allegory In Lā Tukhbir Al-Ḥiṣān, Noha Hanafy

English Language and Literature

This article explores sibling relations in Mamdūḥ ‘Azzām’s (1950- ) Lā tukhbir al-ḥiṣān (2019, Don’t Tell the Horse). Using Mikhail Bakhtin’s (1895-1975) theories on the dialogic nature of the novel and the polyphony of voices existing in a single text, the article charts the characters’ movement in and out of the different storylines in ‘Azzām’s novel, and the way in which this informs the dynamic of the family story. Lending itself to multiple perspectives, ‘Azzām’s novel foregrounds the siblings’ voices over a singular authorial voice, highlighting not only their relationships in the novel, but also the way they offer …

Efficacy Of Kairomone Lures To Attract Parasitoids Of Halyomorpha Halys, Kate V Richardson, Diane G Alston, Lori R Spears

Faculty, Staff and Student Publications

In its native range, Halyomorpha halys (Stål) is suppressed by parasitoids in the genus Trissolcus (Hymenoptera: Scelionidae). Trissolcus native to Utah have demonstrated low parasitism of H. halys, while adventive Trissolcus japonicus (Ashmead) have shown parasitism of up to 20%. Custom rubber septa lures containing stink bug kairomones, n-tridecane (attractant), and (E)-2-decenal (repellent), at 100%, 90%, and 80% levels of attractant (10 mg load rate), were placed adjacent to sentinel H. halys egg masses in northern Utah field trials. Egg masses were evaluated for the presence and intensity (proportion of parasitized eggs) of parasitism. Parasitism by T. japonicus and …

Law Over Legalism: International Court Legitimacy In Lautsi V. Italy, Sebastián Guidi

Duke Journal of Comparative & International Law

2009 brought an existential crisis to the European Court of Human Rights (ECtHR). In November, it unanimously ordered Italy to remove crucifixes from public schools. Backlash was unprecedented. The government promptly announced it would not comply. Politicians and social actors all across the political spectrum harshly criticized the decision and bashed the Court. Ten European countries joined Italy in referring the case to the Grand Chamber of the Court, which reversed the decision in 2011. The storm abated. Lautsi v. Italy likely received the most public attention of any ECtHR judgment. Much of the Court’s subsequent case-law was decided with …

In-Vial Detection Of Protein Denaturation Using Intrinsic Fluorescence Anisotropy, Krishnakumar Chullipalliyalil, Khaled Elkassas, Michael Mcauliffe, Sonja Vucen, Abina Crean

Cappa Publications

The conventional quality control techniques for identifying the denaturation of biopharmaceuticals includes sodium dodecyl sulfate-polyacrylamide gel electrophoresis for identifying fragmentation, ion exchange chromatography and isoelectric focusing for identifying deamidation, reverse-phase high-performance liquid chromatography (HPLC) for identifying oxidation, and size-exclusion HPLC for identifying aggregation. These stability assessments require essential processes that are destructive to the product tested. All these techniques are lab based and require sample removal from a sealed storage vial, which can breach the sterility. In this work, we investigate the heat- and surfactant-induced denaturation of an in-vial-stored model protein, bovine serum albumin (BSA), by analyzing its intrinsic fluorescence …

White Christian Nationalism Enters The Political Mainstream: Implications For The Roberts Court And Religious Freedom, Stephen M. Feldman

Seton Hall Law Review

No abstract provided.

Beyond The Usual Suspects: Emerging Uropathogens In The Microbiome Age, Robert B. Moreland, Brian I. Choi, Wilson Geaman, Caroline Gonzalez, Baylie R. Hochstedler-Kramer, Jerrin John, Jacob Kaindl, Nikita Kesav, Jyoti Lamichhane, Luke Lucio, Malika Saxena, Aditi Sharma, Lana Tinawi, Michael E. Vanek, Catherine Putonti, Linda Brubaker, Alan J. Wolfe

Biology: Faculty Publications and Other Works

The advent of sensitive enhanced culture (metaculturomic) and culture-independent DNA-based (metagenomic) methods has revealed a rich collection of microbial species that inhabit the human urinary tract. Known as the urinary microbiome, this community of microbes consists of hundreds of distinct species that range across the entire phylogenetic spectrum. This new knowledge clashes with standard clinical microbiology laboratory methods, established more than 60 years ago, that focus attention on a relatively small subset of universally acknowledged uropathogens. Increasing reports support the hypothesis that this focus is too narrow. Single uropathogen reports are common in women with recurrent urinary tract infection (UTI), …