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Charge-Voltage Curves Of Shaker Potassium Channel Are Not Hysteretic At Steady State, John Cowgill, Baron Chanda

2020-Current year OA Pubs

Charge-voltage curves of many voltage-gated ion channels exhibit hysteresis but such curves are also a direct measure of free energy of channel gating and, hence, should be path-independent. Here, we identify conditions to measure steady-state charge-voltage curves and show that these are curves are not hysteretic. Charged residues in transmembrane segments of voltage-gated ion channels (VGICs) sense and respond to changes in the electric field. The movement of these gating charges underpins voltage-dependent activation and is also a direct metric of the net free-energy of channel activation. However, for most voltage-gated ion channels, the charge-voltage (Q-V) curves appear to be …

International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis – 2023, Sarah K. Wise, Cecelia C. Damask, Lauren T. Roland, Charles Ebert, Joshua M. Levy, Sandra Lin, Amber Luong, Kenneth Rodriguez, Ahmad R. Sedaghat, Helene J. Krouse

School of Medicine Publications

Background

In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the 2018 document. Originally presented topics from 2018 have also been reviewed and updated. The executive summary highlights key evidence-based findings and recommendation from the full document.

Methods

ICAR-Allergic Rhinitis 2023 employed established evidence-based review with recommendation (EBRR) methodology to individually evaluate each topic. Stepwise iterative peer review and consensus …

Hypervirulent R20291 Clostridioides Difficile Spores Show Disinfection Resilience To Sodium Hypochlorite Despite Structural Changes, Dmitry Malyshev, Imogen Anne Jones, Matthew Mckracken, Rasmus Öberg, Glenn M. Harper, Lovleen Tina Joshi, Magnus Andersson

Peninsula Dental School

No abstract provided.

Characteristics Of The Efficiency Of Actions Of Top-Level Goalkeepers In Soccer, Andrzej Szwarc, Michał Chamera, Henryk Duda, Daniel Memmert, Lukasz Radziminski

Baltic Journal of Health and Physical Activity

The aim of this study was to present the characteristics of the actions efficiency in elite goalkeepers. 54 observations of 25 goalkeepers participating in 27 matches of the World and the European Championships and the Africa Cup of Nations and Copa America held in the years 2014–2019 were included. The study applied a method of observation. Game data were registered on a self-developed observation sheet. Goalkeepers’ activity, effectiveness, and reliability with a view to implementing the objectives of the game were analyzed in offensive and in defense. It was found that in the elite goalkeepers’ game, offensive actions constitute 62% …

Force Majeure & Covid-19: A Clause Changed?, Claudia Petcu

DePaul Business & Commercial Law Journal

No abstract provided.

Sr 22-23-31 Cc, Marshall University Faculty Senate

Recommendations

No abstract provided.

The Impact Of Covid-19 On Students' Academic Performance: The Case Of The University Of Ghana Business School, Joseph Ofori Acheampong

Political Science Student Research

The unruly consequences of the COVID-19 outbreak have hamstrung higher education institutions. This study aims to investigate the perceived impact of COVID-19 on student learning and academic performance through a qualitative approach. In-depth semi-structured interviews with 30 purposively chosen informants were used. The results indicated that 70% of students perceive a paradigm shift in their learning experience before and after COVID-19. It was discovered that their sociodemographic characteristics influenced 60% of students, and 57% were influenced by their parent's socioeconomic status, which influenced their academic achievements during the COVID-19 outbreak. The findings revealed that 63% of students had faced numerous …

Back Matter Vol.59 No.1 [3/2023], Folia Medica Indonesiana

Folia Medica Indonesiana

No abstract provided.

“It’S Just Hard Reaching Out”: Factors Affecting Help-Seeking Behaviors Among Independent College Students., Beth Sapiro, Svetlana Shpiegel, Silvia Ramirez Quiroz, Marissa Ventola, Oomi Helen Nwankwo, Tariro Munyereyi

Department of Social Work and Child Advocacy Faculty Scholarship and Creative Works

Independent students pursue higher education without financial, practical, and sometimes emotional support from family. For these students, asking for assistance when needed is key for college persistence. Decisions around help-seeking are shaped by multiple factors but are often portrayed as a solely individual decision. This study examined factors affecting help seeking among independent students enrolled in a four-year university. Within a process evaluation of a campus support program for independent students, we conducted in-depth, individual interviews with 23 independent students ages 18–23, as well as 5 university staff. Students described a range of psychological and relational factors influencing their willingness …

Blind Luck: A Narrative Exploration Of French Sayings And Superstitions, Isabella North

Honors Program: Senior Projects (Public)

The goal of this Honors Thesis was to explore French superstitions and idioms through a fictional story. To facilitate the inclusion of a range of sayings and superstitious beliefs, the short story “Jamais Deux Sans Trois” is a borderline paranormal piece of fiction which is meant to call into question how the reader interprets the world. The story, written in French, revolves around a pair of best friends and their experiences with a series of events which may or may not be explained through the lens of superstitions, depending on which character is asked at which point in the story. …

“Buried In The Bones”: Medical Racial Trauma And Mistrust In Black Families, Destiny Jelks

LSU Master's Theses

This exploratory study used a mixed-methods design and phenomenological approach to examine the ways in which the United States’ history of medical racism impacts Black young adults and their attitudes toward the healthcare system as well as healthcare utilization. This study examines the phenomenon through the lense of critical race theory, family systems theory, and historical trauma theory. This study also explored the concept of the intergenerational transmission of trauma focusing on medical racial trauma and medical mistrust in Black families.

Molecular And Cellular Level Characterization Of Cytoskeletal Mechanics Using A Quartz Crystal Microbalance, Emily M. Kerivan, Lyle Tobin, Mihir Basil, Dana N. Reinemann

Faculty and Student Publications

A quartz crystal microbalance (QCM) is an instrument that has the ability to measure nanogram-level changes in mass on a quartz sensor and is traditionally used to probe surface interactions and assembly kinetics of synthetic systems. The addition of dissipation monitoring (QCM-D) facilitates the study of viscoelastic systems, such as those relevant to molecular and cellular mechanics. Due to real-time recording of frequency and dissipation changes and single protein-level precision, the QCM-D is effective in interrogating the viscoelastic properties of cell surfaces and in vitro cellular components. However, few studies focus on the application of this instrument to cytoskeletal systems, …

Nutritional Knowledge And Body Mass Index Among Students At Novena University, Ogume, Nigeria, Udi Onoriode Andrew, Okoro Ogheneyebrorue Godswill, Enaowho Taniyowho Mamerhi, Douglas Boma

Folia Medica Indonesiana

Highlights: • Interviews were conducted on the correlation between nutritional knowledge and BMI among students at Novena University, Ogume, Nigeria. • Most of the students had adequate nutritional knowledge and a low obesity prevalence rate. Abstract: Body mass index (BMI), which is calculated using height and weight, is a rough indicator of body fat. This study aimed to investigate whether there is a significant correlation between nutritional knowledge and BMI among students at Novena University, Ogume, Nigeria. This study was done using a cross-sectional survey. Interviews were conducted with 50 participants from the sample, whose nutritional knowledge and weight status …

Expressions Of Β-Tryptase And Chymase In Lung Mast Cells Due To Anaphylactic Shock Through Histopathological Appearance At Different Post-Mortem Intervals, Biqisthi Ari Putra, Imam Susilo, Ahmad Yudianto

Folia Medica Indonesiana

Highlights: • The post-mortem interval is related to tryptase and chymase expressions in anaphylactic shock incidence • Forensic experts can utilize tryptase and chymase as markers of anaphylactic (non-anaphylactoid) shock that occurs in the lungs. Abstract: Anaphylactic shock is a hypersensitivity response, a commonly type I hypersensitivity involving immunoglobulin E (IgE). It is caused by an antigen-antibody reaction that occurs immediately after a sensitive antigen enters the circulation. Anaphylactic shock is a clinical manifestation of anaphylaxis that is distributive shock, characterized by hypotension due to sudden blood vessel vasodilation and accompanied by a collapse in blood circulation that can result …

Surgical Site Infection Caused By Non-Hemolytic Staphylococcus Aureus Following A Total Knee Arthroplasty At A Class C Hospital In Indonesia, Satiyo, Elsye Maria Rosa

Folia Medica Indonesiana

Highlights: • A patient with grade IV osteoarthritis underwent an arthroplasty and developed a surgical site infection caused by Staphylococcus aureus. • The treatment for the surgical site infection included antibiotic medications and revision surgery for the previous total knee arthroplasty. Abstract: This article presents a case report of a knee arthroplasty surgical site infection caused by non-hemolytic Staphylococcus aureus. A 56-year-old woman came to the Orthopedic Outpatient Clinic, with the chief complaint of pain in the left knee for the last three years. After being diagnosed with grade IV osteoarthritis, the patient underwent a total knee arthroplasty. The patient …

Front Matter Vol.59 No.1 [3/2023], Folia Medica Indonesiana

Folia Medica Indonesiana

No abstract provided.

The Social Environment Alters Neural Responses To A Lipopolysaccharide Challenge, Patricia C. Lopes, Josh J. Faber-Hammond, Chandler Siemonsma, Sachin Patel, Suzy C.P. Renn

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Sick animals display drastic changes in their behavioral patterns, including decreased activity, decreased food and water intake, and decreased interest in social interactions. These behaviors, collectively called “sickness behaviors”, can be socially modulated. For example, when provided with mating opportunities, males of several species show reduced sickness behaviors. While the behavior is known to change, how the social environment affects neural molecular responses to sickness is not known. Here, we used a species, the zebra finch, Taeniopygia guttata, where males have been shown to decrease sickness behaviors when presented with novel females. Using this paradigm, we obtained samples from …

Response Of Dissolved Organic Carbon Dynamics To Salinity In A Constructed Fen Peatland In The Athabasca Oil Sands Region, Emily Prystupa, Scott J. Davidson, Jonathan Price, Maria Strack

School of Geography, Earth and Environmental Sciences

In northern Alberta, oil sands mining disturbs the boreal landscape, and reclamation to an ‘equivalent land capability’ is required. Industry is testing peatland construction as part of landscape reclamation. To determine if constructed peatlands can be self-sustaining, an understanding of the cycling of solutes in pore water and their interactions with dissolved organic carbon (DOC) is needed since DOC can represent an important carbon loss from peatlands. DOC is of interest due to its biotic origin and use by the microbial community and impact on carbon budgets. Additionally, salinity as a control on DOC quantity and quality may be important …

Session Iiib Psychology/Sociology Presentation 4 - College Involvement On Campus And Its Relationship To Undergraduate Gpa, Marissa Dimatteo

Life of the Scholar Multidisciplinary Conference

Student involvement on campus is important for promoting academic success. Involvement on campus builds confidence, exposes students to possibilities, and leads to positive attitudes towards learning. Extracurricular activities such as academic clubs, varsity sports, intramural sports, and research are activities that could help students be more involved and increase the satisfaction of their college experience. The purpose of this research was to determine if students with high involvement on campus were correlated with a high GPA.

Session Ii: Faculty Showcase Presentation 3 - Beware Of Bogus Barcodes, Dr. David Campbell

Life of the Scholar Multidisciplinary Conference

Certain DNA sequences are promoted as a barcode for easily identifying organisms. But actual biology is messier than that. I discuss some problems with this approach, as well as potential, reflecting issues encountered in my research.

Session Ic: Natural Sciences Presentation 2 - Isolation Of Citral From Lemongrass: Steam Distillation, Spectroscopy, And Gc-Ms Analysis, Nicole L. Riha

Life of the Scholar Multidisciplinary Conference

For my summer scholars project, I worked to isolate citral oil from fresh lemongrass, which has a high citral content in its oil. Extraction was done by performing a steam distillation. Oil was then analyzed with various forms of spectroscopy to confirm the presence of citral. This experiment expanded on a previous study. According to research, citral has anti-microbial, anti-fungal, anti-inflammatory, and anti-cancer properties.

Multi-Year Analysis Of Groundwater Temperature Fluctuations In A Shallow Aquifer Sysytem Influenced By A Tile-Drain, Jack Thomas Wassik

Theses and Dissertations

Groundwater temperature plays a significant role in regulating geochemical, biological and physical processes with the subsurface with wide ranging environmental and societal impacts. Air temperature, weather conditions and lithology exhibit control on magnitude and timing of thermal responses that ultimately control groundwater temperature. Historical groundwater, tile water, stream and air temperature data from the T3 site were analyzed, including groundwater temperature data from multiple depths was analyzed. Additionally, statistical analyses between the temperature datasets were performed in order to interpret potential relationships. Air temperature was found to be the primary control of groundwater temperatures, though its affect being muted as …

Espacios E Imaginario En El Sueño De Mariana (2008) De Jorge Galán, Emilie Boyer

Alambique. Revista académica de ciencia ficción y fantasía / Jornal acadêmico de ficção científica e fantasía

En este artículo, se propone un estudio de la novela de ciencia ficción El sueño de Mariana (2008) de Jorge Galán a partir de los conceptos de “espacio” e “imaginario”. Demostramos, cómo, a través de un mundo donde los sueños posthumanistas se hicieron realidad, el imaginario, sinónimo de libertad, es el pretexto de opresión y marginalización de una parte de la población. Es entonces reemplazado por el desvanecimiento supuesto de los límites de la realidad a través de un uso engañoso de la imagen, como reproducción traidora de una realidad más auténtica. Gracias a una compleja representación del sueño, de …

The Future In Fragments: Three Critical Dystopian Works By Fernando Contreras Castro, Matthew Richey

Alambique. Revista académica de ciencia ficción y fantasía / Jornal acadêmico de ficção científica e fantasía

In the prologue to the 2014 edition of Cantos de las Guerras Preventivas, Costa Rican author Fernando Contreras Castro states that the novel, originally published in 2006, originated as a response to the ambiguously-defined military campaigns that dominated the global geopolitical landscape during the first decade of the 21st century. Contreras Castro further explains that the novel is an attempt at imagining near-future worlds from a distinctly Latin American perspective, while avoiding the currents of cyberpunk and paranoid fiction that dominated late 20th century science fiction writing in the United States. The novel also marks a significant departure from …

Insentient “Cognition”?, Stevan Harnad

Animal Sentience

A sentient state is a state that it feels like something to be in. Cows have them, cars don’t. Cognitive capacities are a subset of behavioral capacities. Not all behavioral capacities are cognitive (but the distinction is fuzzy). Might the difference have something to do with whether the behaver is sentient?

Do Ceo Gratification Preferences Influence Accounting Choices Near Retirement?, Nicholas Wilson

College of Business: Dissertations, Theses, and Student Research

CEOs near retirement are less motivated to act in shareholders' best interests than those planning to remain indefinitely; this is the horizon problem. Financial reporting that personifies the horizon problem includes an abrupt reduction in discretionary spending and an increase in current accounting earnings; this abrupt change in reporting is potentially detrimental to long-term gains. Gratification preference, defined by observable tendencies, is a personal characteristic reflecting one's prior life experiences and environments. This study offers an archival measure of these gratification preferences and examines whether these preferences mitigate or exacerbate the CEO horizon problem. The results suggest that discretionary accounting …

Child Weight Status: The Role Of Feeding Styles And Highly Motivated Eating In Children, Maria A Papaioannou, Thomas G Power, Teresia M O'Connor, Jennifer O Fisher, Nilda E Micheli, Sheryl O Hughes

Children’s Nutrition Research Center Staff Publications

Although parental feeding plays an important role in child eating and weight status, high food motivation among children may also be a factor shaping how feeding impacts child weight. This study explored whether individual differences in preschool children’s food motivation interacted with mothers’ feeding styles in predicting subsequent child weight status. Participants included 129 Hispanic Head Start mother/child dyads. Data were collected at ages 4–5 years (Time 1) and 7–9 (Time 3). Staff measured heights/weights and observed children in an eating in the absence of hunger task. Mothers reported on feeding styles/practices and children’s eating behaviors. A principal components analysis …

Clinically Adjudicated Reference Standards For Evaluation Of Infectious Diseases Diagnostics, Robin Patel, Ephraim L Tsalik, Scott Evans, Vance G Fowler, Sarah B Doernberg, Antibacterial Resistance Leadership Group

Faculty, Staff and Student Publications

Lack of a gold standard can present a challenge for evaluation of diagnostic test accuracy of some infectious diseases tests, particularly when the test's accuracy potentially exceeds that of its predecessors. This approach may measure agreement with an imperfect reference, rather than correctness, because the right answer is unknown. Solutions consist of multitest comparators, including those that involve a test under evaluation if multiple new tests are being evaluated together, using latent class modeling, and clinically adjudicated reference standards. Clinically adjudicated reference standards may be considered as comparator methods when no predefined test or composite of tests is sufficiently accurate; …

Child Weight Status: The Role Of Feeding Styles And Highly Motivated Eating In Children, Maria A Papaioannou, Thomas G Power, Teresia M O'Connor, Jennifer O Fisher, Nilda E Micheli, Sheryl O Hughes

Faculty, Staff and Students Publications

Although parental feeding plays an important role in child eating and weight status, high food motivation among children may also be a factor shaping how feeding impacts child weight. This study explored whether individual differences in preschool children’s food motivation interacted with mothers’ feeding styles in predicting subsequent child weight status. Participants included 129 Hispanic Head Start mother/child dyads. Data were collected at ages 4–5 years (Time 1) and 7–9 (Time 3). Staff measured heights/weights and observed children in an eating in the absence of hunger task. Mothers reported on feeding styles/practices and children’s eating behaviors. A principal components analysis …

The Ipdgc/Gp2 Hackathon - An Open Science Event For Training In Data Science, Genomics, And Collaboration Using Parkinson's Disease Data, Hampton L Leonard, Ruqaya Murtadha, Alejandro Martinez-Carrasco, Alina Jama, Amica Corda Müller-Nedebock, Ana-Luisa Gil-Martinez, Anastasia Illarionova, Anni Moore, Bernabe I Bustos, Bharati Jadhav, Brook Huxford, Catherine Storm, Clodagh Towns, Dan Vitale, Devina Chetty, Eric Yu, Francis P Grenn, Gabriela Salazar, Geoffrey Rateau, Hirotaka Iwaki, Inas Elsayed, Isabelle Francesca Foote, Zuné Jansen Van Rensburg, Jonggeol Jeff Kim, Jie Yuan, Julie Lake, Kajsa Brolin, Konstantin Senkevich, Lesley Wu, Manuela M X Tan, María Teresa Periñán, Mary B Makarious, Michael Ta, Nikita Simone Pillay, Oswaldo Lorenzo Betancor, Paula R Reyes-Pérez, Pilar Alvarez Jerez, Prabhjyot Saini, Rami Al-Ouran, Ramiya Sivakumar, Raquel Real, Regina H Reynolds, Ruifneg Hu, Shameemah Abrahams, Shilpa C Rao, Tarek Antar, Thiago Peixoto Leal, Vassilena Iankova, William J Scotton, Yeajin Song, Andrew Singleton, Mike A Nalls, Sumit Dey, Sara Bandres-Ciga, Cornelis Blauwendraat, Alastair J Noyce, The International Parkinson Disease Genomics Consortium (Ipdgc) And The Global Parkinson’S Genetics Program (Gp2)

Faculty, Staff and Students Publications

Open science and collaboration are necessary to facilitate the advancement of Parkinson's disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to generate resources and creative solutions to problems. These events can be used as training and networking opportunities, thus we coordinated a virtual 3-day hackathon event, during which 49 early-career scientists from 12 countries built tools and pipelines with a focus on PD. Resources were created with the goal of helping scientists accelerate their own research by having access to the necessary code and tools. Each team was allocated one of …