Digital Commons Network^™

Evaluating The Effects Of Modifying Mixing And Pelleting Parameters On Feed Quality, Pellet Production Rate, And Broiler Performance, Lucas E. Knarr

Graduate Theses, Dissertations, and Problem Reports (ETD)

In Chapter 2, an experiment was conducted to evaluate the effect of different mixer types (MTY) and mix times (MTI) on mix uniformity (MU). A 2 (mix time) x 3 (mixer type) factorial was utilized in this experiment to create six treatments, each mixed in three randomized complete blocks. Mix times were designated adequate or inadequate, were based on the manufacturers’ recommendation, and varied based on the mixer utilized. The mixer types utilized included a vertical mixer, horizontal mixer, and transfer mixing system. The transfer mixing system can be described as a batch-to-mix system …

Three Essays On Political Economy, Colin Michael Steitz

Graduate Theses, Dissertations, and Problem Reports (ETD)

The first chapter studies the impact of conventions and multi-day events on
hotel demand in the Indianapolis metro area. Using hand-collected data on
sporting events and conventions, we study the impact on hotel metrics: ADR,
Occupancy, Daily Rate, and Revenue. We show that traditional sporting
events generate little impact when compared to multi-day conventions. We
show that mega-events such as major championship games generate significant
increases in hotel demand. We find large and statistically significant effects for
multi-day conventions on hotel demand with very little evidence of crowding
out. A single day of a multi-day convention brings in approximately $928,000 …

Effects Of Light/Dark Cycle Shifts On Delay Discounting, Katya A. Nolder

Graduate Theses, Dissertations, and Problem Reports (ETD)

Shift-work conditions are a necessity for the constant provision of certain medical, industrial, and commercial services in modern society. Shift work is associated with the increased risk of many negative health outcomes, including type 2 diabetes, heart disease, reproductive issues, and cancer. Shift workers experience multiple levels of circadian-rhythm disruption, which may increase maladaptive decision making, and this may mediate the relation between shift work and negative health outcomes. Circadian-rhythm disruptions can be systematically investigated in the basic laboratory, and one type of procedure involves changing the light/dark cycle in the animal vivarium. The current study investigated effects of light/dark …

Fast Raising: Digital Fundraising As Interaction Rituals, Matthew P. Hartwell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Twice a year, GamesDoneQuick hosts events that showcase the Speed Running Community, a sub-set of the Video Game Community. Since its inception in 2014 through 2021 GDQ has raised $25.7 million that has been distributed to the Prevent Cancer Foundation and Médecins Sans Frontiers (Doctors without Borders). This collection of studies analyzes the Awesome Games Done Quick 2020 event utilizing the Interaction Ritual Theory framework of Randall Collins to understand how ritualistic social action of this community has been leveraged by event organizers to promote successful crowd funding efforts that benefits organizations outside of the community. Further it expands on …

Footwear Image Quality Classification: Using Subjective Assessments And Objective Image Metrics To Predict Impression Quality, En-Tni Lin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Shoeprints deposited during the commission of a crime vary in quality as a function of numerous factors, such as substrates, media, and the specific physical activities carried out by perpetrators. This variability in impression quality impacts the amount of information available from questioned crime scene impressions, and therefore an examiner's confidence in providing opinions of source attribution. In response, this research attempted to characterize footwear impression quality based on image sharpness, contrast, entropy, homogeneity, noise, quantity of information, and complexity, and to integrate these hand-engineered feature descriptions with subjective opinions of impression quality.

The methodology followed a five-pronged approach. First, …

“I’Ll Tell You No Lies”: An Exploration Of Trauma, Memory, And Violence Against Women In North Carolina Murder Ballads, Madison Ava Helman

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores trauma, memory and violence against women in Western North Carolina murder ballads “Tom Dooley,” “Poor Omie Wise,” “Poor Ellen Smith,” “The Ballad of the Lawson Family,” and “Frankie Silver.” I posit that these ballads were influenced by prescriptive societal conceptions of femininity, which in turn influenced societal ideations of violence against women. Using folklore performance theory, I analyze the text and context of these ballads and their subsequent histories, eventually arriving at a template for polyvocality that incorporates multiple ballad variants and encourages diverse performances.

Probabilistic Short Term Solar Driver Forecasting With Neural Network Ensembles, Joshua Daniell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Commonly utilized space weather indices and proxies drive predictive models for thermosphere density, directly impacting objects in low-Earth orbit (LEO) by influencing atmospheric drag forces. A set of solar proxies and indices (drivers), F_10.7, S_10.7, M_10.7, and Y_10.7, are created from a mixture of ground based radio observations and satellite instrument data. These solar drivers represent heating in various levels of the thermosphere and are used as inputs by the JB2008 empirical thermosphere density model. The United States Air Force (USAF) operational High Accuracy Satellite Drag Model (HASDM) relies on JB2008, and …

Evaluation Of Changes In Cellular Behavior Upon Exposure To Selected Analytes Used In Synthetic Applications, Olivia L. Rose

Graduate Theses, Dissertations, and Problem Reports (ETD)

Metal-organic frameworks (MOFs) are organic crystalline hybrids that have been used for a variety of applications from catalysis to gas storage and drug delivery. Studies have shown that generally, while such frameworks are more biocompatible than similar aspect ratio nanostructures, they are also more prone to transformation and disintegration due to their flexible and fragile nature as resulted from the structure assembly and implemented structure-function relationships. With extensive previous literature showing that materials with nano dimensions such as carbon nanotubes, quantum dots and other nanomaterials have unique physicochemical properties that lead to increased biosystems’ reactivity. With increasing concerns regarding adverse …

Leveraging Data Science To Promote Sustainable Resource Recovery From Organic Waste Streams In Rural Regions, Mohammed Tamim Zaki

Graduate Theses, Dissertations, and Problem Reports (ETD)

Conventional organic waste management practices such as landfilling contribute to global warming and degrade environmental and human health. Alternatively, organic waste can be treated to recover energy, nutrients, and carbon through resource recovery technologies. Data science could benefit such technologies by improving their efficiency through data-driven process modeling along with reducing environmental and economic burdens via life cycle assessment (LCA) and techno-economic analysis (TEA), respectively.

A critical review of 616 peer-reviewed articles published during 2002–2022 was conducted on the use of data science methods in resource recovery from organic waste. Although applications of machine learning (ML) methods have drastically increased …

“Ingenious Entanglements”: Sheriffs, Capitalism, And Civil Society In America, 1750-1850, Chad R. Holmes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sheriffs served as indispensable legal actors who facilitated the expansion of democracy and capitalist transformation, processes that eventually limited their ability to profit from their work and diminished their social status. This dissertation is organized around specific sheriffs and the actions they performed to illustrate how county officers influenced society beyond the execution of court orders. These men—Rhode Island’s Beriah Brown, Pennsylvania’s John Barker, and Massachusetts’s Elisha Porter, Luke Baldwin, and Charles P. Sumner—believed they understood how to balance community demands and state directives in ways that would produce personal profit and greater authority. The work of these officers and …

Effects Of Oxycodone And Methylphenidate On Self-Control With Aversive Outcomes, Jeremy Saul Langford

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the context of choice, one is said to show self-control under numerous conditions in which consideration is given to the delayed outcomes of each option. This can be difficult: both reinforcing and aversive outcomes become less effective as they are increasingly delayed. Several socially significant issues arise from a failure of delayed, aversive outcomes to impact choice, especially when immediate, reinforcing outcomes are available. Identifying the conditions under which choice is sensitive to delayed outcomes is critical to shifting choices toward alternatives in which contact with delayed, aversive outcomes is minimized. Two experiments were conducted with the aim of …

Microwave-Assisted Ammonia Synthesis Over Cs-Ru/Ceo2 Catalyst, Alazar Kesete Araia

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ammonia synthesis is one of the greatest innovations of the 20^th century with extensive applications from fertilizers to intermediates for nitrogen-containing chemicals and pharmaceuticals. Annually, more than 242 million tons of ammonia is produced globally, supporting approximately 27% of the world’s population. One of the fast-growing applications for ammonia is as H₂ energy carrier due to its high energy storage capacity, considered to be a decarbonized energy source. The low volumetric energy density and incompressibility makes Hydrogen a non-preferable energy carrier; an alternative carrier becomes a requirement. Ammonia possesses unique property as an energy-dense carrier to store and …

Cue Reactivity In Non-Smoking Electronic Cigarette Users, Ashley E. Douglas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Electronic cigarettes (ECIGs) are among the most popular nicotine products in the United States, particularly among youth and young adults. Many individuals who use ECIGs report an interest in quitting or unsuccessful quit attempts. In addition to nicotine dependence, one factor that may contribute to continued ECIG use is an individual’s response to ECIG-related environmental stimuli, or cues. Existing research demonstrates that exposure to ECIG cues increases craving for ECIGs among cigarette smokers, including those without previous ECIG experience. The purpose of this study was to examine effects of ECIG cue exposure in experienced ECIG users with minimal smoking history, …

Right Treatment Wrong Time: Immunotherapy Administration Post-Radiotherapy Decreases Tumor Burden In A Preclinical Model Of Brain Metastasis, Kathryn Elizabeth Blethen

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation (a) provided an in-depth literature review of methods to modulate the blood-brain and blood-tumor barriers to increase drug delivery and efficacy in brain metastases, (b) evaluated the effects of whole-brain radiation therapy on the blood-brain barrier in immunocompetent and immunocompromised mouse models and proposed a mechanism by which the immune response to radiation disrupts the blood-brain barrier, and (c) developed a syngeneic lung cancer brain metastasis model to determine the impact of coordinated immunotherapy administration with radiotherapy. The blood-brain barrier is an impediment to drug delivery to the brain. The inherent leakiness of the blood-tumor barrier does not …

Glial Cell-Specific Contribution Of Pkr-Like Er Kinase (Perk) In Neuroinflammation And Behavior, Anirudhya Lahiri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neurological disorders such as multiple sclerosis (MS) are a major public health concern in the US, with no available therapeutic cure. Chronic neuroinflammation and aberrant proteostasis in the central nervous system (CNS) are the major hallmarks of neurological diseases. Endoplasmic Reticulum (ER) is a major cellular organelle involved in protein synthesis, folding and maturation of various secretory and transmembrane proteins. Pathophysiological stressors such as trauma and infection result in misfolded protein accumulation in the endoplasmic reticulum (ER) lumen, which results in ER stress. To regain proteostasis (protein homeostasis), cells activate the unfolded protein response (UPR). UPR is an evolutionarily conserved …

Evaluate A Mixer Of Hydrogen Peroxide And Peroxyacetic Acid To Mitigate Microbial Cross-Contamination Of Salmonella Typhimurium And The Surrogate Enterococcus Faecium During Triple-Washing Of Butternut Squash, Jesica M. Temple

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Recent foodborne illness outbreaks have been linked to fresh fruits and vegetables. For public safety, awareness of the risks of contamination from foodborne pathogens that can occur during post-harvest farming practices is essential to prevent foodborne outbreaks. Controlling the spread of foodborne pathogens on produce requires proper washing procedures, antimicrobials and doses. Given the speed and diversity of the produce being distributed, local incidents may become international emergencies. Methods: Studies were included if they assessed the efficacy of antimicrobials and various washing procedures and had to conclude the mitigation of cross-contamination of foodborne pathogens on produce grown in the …

Role Of Ca2+ In Healthy And Pathologic Cardiac Function: From Normal Excitation–Contraction Coupling To Mutations That Cause Inherited Arrhythmia, Joshua A Keefe, Oliver M Moore, Kevin S Ho, Xander H T Wehrens

Faculty, Staff and Students Publications

Calcium (Ca2+) ions are a key second messenger involved in the rhythmic excitation and contraction of cardiomyocytes throughout the heart. Proper function of Ca2+-handling proteins is required for healthy cardiac function, whereas disruption in any of these can cause cardiac arrhythmias. This comprehensive review provides a broad overview of the roles of Ca2+-handling proteins and their regulators in healthy cardiac function and the mechanisms by which mutations in these proteins contribute to inherited arrhythmias. Major Ca2+ channels and Ca2+-sensitive regulatory proteins involved in cardiac excitation–contraction coupling are discussed, with special emphasis on the function of the RyR2 macromolecular complex. Inherited …

Perception Of Bias In Chatgpt: Analysis Of Social Media Data, Abdullah Wahbeh, Mohammad Al-Ramahi, Omar F. El-Gayar, Tareq Nasralah, Ahmed Elnoshokaty

Research & Publications

In this study, we aim to analyze the public perception of Twitter users with respect to the use of ChatGPT and the potential bias in its responses. Sentiment and emotion analysis were also analyzed. Analysis of 5,962 English tweets showed that Twitter users expressed concerns regarding six predominant types of biases, namely: political, ideological, data and algorithmic, gender, racial, cultural, and confirmation biases. Sentiment analysis showed that most of the users reflected a neutral sentiment, followed by negative and positive sentiment. Emotion analysis mainly reflected anger, disgust, and sadness with respect to bias concerns with ChatGPT use.

The Well-Being Of A University: The Relationship Between Gratitude And Organizational Commitment On Faculty Members' Intention To Stay, Brenda Merkel, Kristi Bockorny, Amber Henderson, Aaron Scholl

Research & Publications

Retaining good employees can be difficult , and no organization is immune. This study investigated the relationship between gratitude and organizational commitment to determine if they can predict the intention to stay among university faculty. Specifically, this study analyzed gratitude, a construct that has not been researched much in the workplace. There was a significant relationship between gratitude on organizational commitment. Gratitude and organizational commitment were important predictors of intention to stay. Gratitude was supported as a moderator between organizational commitment and intention to stay. Organizations should incorporate posititve reinforcements to express gratitude to increase organizational commitment and intent to …

The Magnetic Pull Of American Discovery: Second Thoughts About American Exceptionalism?, Richard L. Marcus

Faculty Scholarship

No abstract provided.

Patent Term Extensions And The Last Man Standing, Robin Feldman

Faculty Scholarship

In 1984, with the passing of the Hatch-Waxman Act, Congress orchestrated a compromise that permanently changed how drug markets operate. This piece of legislation created an expedited pathway for generics to enter the market, and, in exchange, brand drugs could extend their patents to account for time lost during their market approval process. Although this well-configured trade was supposed to help generics enter the scene quicker, the current drug market landscape makes one question whether this legislation has succeeded in its aims. The following study explores the lifecycle of top-selling brand drugs in comparison to the vision put forth by …

Leading With The Trailing Edge: Facilitating Patient Choice For Insulin Products, Robin Feldman

Faculty Scholarship

Insulin prices have risen sharply, despite a century since its introduction. Against this backdrop, companies have discontinued dozens of insulin prod- ucts. Discontinuation could relate to safety or effectiveness, or to the over- whelming benefits of newer products. On the other hand, discontinuation could suggest strategic behavior hampering competition and supporting prices. To test these theories, this project examined every insulin discontin- uation, analyzing the role discontinuations play in insulin affordability. No evidence emerged of any discontinuation for safety or effectiveness. Rather, dozens of viable products were removed from the market, followed by more expensive versions, often with little or …

Restorative Justice Diversion As A Structural Health Intervention In The Criminal Legal System The Criminal Legal System, Thalia Gonzalez

Faculty Scholarship

A new discourse at the intersection of criminal justice and public health is bringing to light how exposure to the ordinariness of racism in the criminal legal system—whether in policing practices or carceral settings—leads to extraordinary outcomes in health. Drawing on empirical evidence of the deleterious health effects of system involvement coupled with new threats posed by COVID-19, advocates and academics have increasingly called for race-conscious public health-driven reforms to carcerality in the United States. Recognizing the significance of health to carceral reform, the initiation of a health justice grounded lexicon in criminal justice has opened the doorway to new …

Data Integration With Diverse Data: Aerospace Industry Insights From A Systematic Literature Review, Cherie Noteboom, Olga Perera

Research & Publications

Data Integration (DI) is a technical framework that facilitates the integration of different data sources into a unified system. Often, organizational data is spread across various files, databases, and personal computers, resulting in data silos and difficulties in accessing vital organizational knowledge. The solution rests in the development of Information Systems capable of handling diverse data from multiple heterogeneous sources. This study presents a systematic literature review on data integration approaches, specifically focusing on the aerospace industry. We conducted a literature search on IEEE Xplore database with keywords ‘data integration aerospace’ for articles published between January 2000 and December 2022 …

How Salinity Influences Soil Organisms: Earthworms, Archaea, Bacteria And Fungi, Cecelia Bartley Castleberry

Soil Science

Soil salinity is a naturally-occurring issue in the Great Plains. Current standards for saline soil designation are based on plant tolerance levels. This thesis expands salinity knowledge into salinity responses of other soil organisms. I used laboratory mesocosms to examine survival and fecundity or cocoon production of earthworms in the Apporectodea complex to increasing levels of salinity, with or without supplemental organic matter (OM). I then used a split-bin design to examine earthworm choice between combinations of saline and non-saline soils, with and without supplemental OM. I found that earthworms avoided saline soils, but survival and production was steady across …

Versican Provides The Provisional Matrix For Uterine Spiral Artery Dilation And Fetal Growth, Yusuke Sagae, Akihito Horie, Akihiro Yanai, Tsutomu Ohara, Baku Nakakita, Yoshimi Kitawaki, Asuka Okunomiya, Hirohiko Tani, Ken Yamaguchi, Junzo Hamanishi, John P Lydon, Takiko Daikoku, Hideto Watanabe, Masaki Mandai

Faculty, Staff and Students Publications

The extracellular matrix (ECM) in the endometrium plays a crucial role in mammalian pregnancy. We have shown that versican secreted from the endometrial epithelium promotes embryo implantation. Versican is a proteoglycan, a major player in the provisional matrix, and versikine, its N-terminal fragment cleaved by ADAMTS proteinases, serves as a bioactive molecule. Here, since versican expression in the placenta was dynamically altered in humans and mice, we investigated the role of versican in pregnancy using uterine-specific Vcan deletion mice (uKO mice) and ADAMTS-resistant versican expressing mice (V1R mice). uKO mice exhibited insufficient spiral artery dilation, followed by fetal growth restriction …

Concurrent Idh1 And Idh2 Mutations In Glioblastoma: A Case Report, Ali S Haider, Chibawanye I Ene, Paolo Palmisciano, Maryam Haider, Ganesh Rao, Leomar Y Ballester, Gregory N Fuller

Faculty, Staff and Students Publications

Isocitrate dehydrogenase (IDH) mutations are cornerstone diagnostic features in glioma classification. IDH mutations are typically characterized by mutually exclusive amino acid substitutions in the genes encoding for the IDH1 and the IDH2 enzyme isoforms. We report our institutional case of a diffuse astrocytoma with progression to secondary glioblastoma and concurrent IDH1/IDH2 mutations. A 49-year-old male underwent a subtotal resection of a lobular lesion within the right insula in 2013, revealing a WHO grade 3 anaplastic oligoastrocytoma, IDH1 mutated, 1p19q intact. Symptomatic tumor progression was suspected in 2018, leading to a surgical tumor biopsy that demonstrated WHO grade 4 IDH1 and …

Understanding Visitor Recreation Experiences On Montana's Public Lands, Kara Grau, Megan Schultz, Glenna Brown, Melissa Weddell

Institute for Tourism and Recreation Research Publications

The grandeur of Montana’s public lands attracts visitors from all over the world who want to experience the beautiful parks, wilderness, wildlife, and waters. Montana is ranked 10th in the nation in federal land ownership, with about 30% or 27 million acres, followed by state agencies that manage a little over 5 million acres. Moreover, Montana is the gateway to the iconic Glacier and Yellowstone National Parks.

Nursing Students' And Recent Graduates' Observations Of Fatphobia In The Clinical Setting, Myah Kerbyson

Honors Theses and Capstones

Objectives: To investigate the incidence of fatphobic behaviors among the healthcare team and how nursing students’ and recent graduates’ observations of fatphobic behaviors impact the provision of affirming care.

Background: Weight stigma among healthcare providers can lead to fatphobia (e.g., hurtful or stigmatizing language, dismissal of symptoms). These experiences can negatively impact patients’ health and experiences with healthcare, leading some patients to avoid or delay seeking healthcare services. Fatphobia can also cause increased stress levels among patients, which places them at a higher risk of several diseases. The short-term and long-term effects of fatphobia lead overall worse health outcomes.

Methods: …

Environmental Evaluation Of The Alternative Housing Environments Of Slums, Aya Abd El-Maksoud Maan, Alaa Mohamed Shams, Mohanad Ali Fouda

Mansoura Engineering Journal

The government has built many similar units all over Egypt, especially Cairo, without considering the differences between residents, studying the areas from which they came, or preparing the neighborhoods they moved to, and they did not follow Vision 2030, which stipulates achieving sustainability in modern urban societies. The research aims to prepare alternative housing areas to be environmentally sustainable and to provide guiding principles for the design of alternative residential neighborhoods. The researcher used the applied approach to the Asmarat neighborhood as one of the built-up neighborhoods to solve the problem of slums in Cairo and was evaluated by the …