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2023

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Skirting The Law: Sensationalism And Spectacle Of British Murderesses From The 1830s To The 1860s, Sarah Elizabeth Offutt Jan 2023

Skirting The Law: Sensationalism And Spectacle Of British Murderesses From The 1830s To The 1860s, Sarah Elizabeth Offutt

Graduate Theses, Dissertations, and Problem Reports (ETD)

“Skirting the Law: Sensationalism and Spectacle of British Murderesses from the 1830s to the 1860s” concentrates on women who committed the crime of murder during a time where print culture rose in popularity, gendered spheres of influence dictated lives, and class consciousness governed society. Due to their rarity and uniqueness, murderesses became a fascination among the public as they defined societal expectations. While some women inspired sympathy for their plight that led to their actions, others were viewed as wicked and abominations of nature. When observing how infrequently women were convicted in comparison to men, the thesis argues that their …


Meiotic Recombination In Zea Mays And Its Contribution To Genetic Diversity, Jasmine Elizabeth Freeman Jan 2023

Meiotic Recombination In Zea Mays And Its Contribution To Genetic Diversity, Jasmine Elizabeth Freeman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Meiotic recombination plays a vital role in shaping genome evolution by introducing genetic diversity necessary for natural selection. Recombination rates exhibit extensive variation within and between species, occurring in specific regions known as hotspots and coldspots along individual chromosomes. Maize, with its well-characterized genome, provides an excellent model for studying the nonrandom pattern of meiotic recombination. While retrotransposon activity contributes to significant intergenic variation in maize inbred lines, the genic space remains conserved in terms of gene order and sequence. To investigate recombination activity in the Bz1/Sh1 region, the maize haplotypes W22 and B73, which share genetic backgrounds but differ …


An Examination Of Counselor Turnover And Its Impact On Quality Behavioral Health Services, Leslie M. Beale Jan 2023

An Examination Of Counselor Turnover And Its Impact On Quality Behavioral Health Services, Leslie M. Beale

Walden Dissertations and Doctoral Studies

Behavioral health organizations often face the challenge of high employee turnover rates, which can critically affect their ability to treat mental illnesses successfully. High counselor turnover at one such organization, BHOX, threatens the provision of timely access to quality mental care. This qualitative case study examined counselor turnover and its impact on the quality of behavioral health services. The Baldrige Excellence Framework was used to guide this descriptive case study of a nonprofit behavioral health organization on the East Coast of the United States, which serves men and women struggling with mental health disorders and substance abuse addictions. The data …


Using Extended Two-Step Floating Catchment Area To Map Children’S Level Of Access To Physical Books In West Virginia, Heather A. Maxey Jan 2023

Using Extended Two-Step Floating Catchment Area To Map Children’S Level Of Access To Physical Books In West Virginia, Heather A. Maxey

Graduate Theses, Dissertations, and Problem Reports (ETD)

The state of West Virginia lacked a comprehensive, in-depth analysis of the availability of physical books across the state. Access to reading material is vital to a child’s educational development as well as lifelong learning beyond childhood. To guide policy decisions and planning for outreach which addresses reading levels and beyond, I mapped levels of access stemming from socioeconomic barriers, spatial barriers, and an integrated index of both types of barriers. To map spatial access, I utilized a modified Extended Two-Step Floating Catchment Area model, deriving techniques from Hong et al’s 2023 article addressing access for health care in WV. …


Found And Fabricated, Molly S. Davis Jan 2023

Found And Fabricated, Molly S. Davis

Graduate Theses, Dissertations, and Problem Reports (ETD)

My MFA written thesis addresses work completed and shown in a thesis exhibition at West Virginia University as well as significant influences to my studio process. While my stated focus is sculpture, the work presented in the exhibition consisted of three sculptural pieces and two sets of prints. This thesis, along with the supporting exhibition, addresses my investigations into the physical properties and tendencies of materials and how that information can guide and inform a work of art. Physical characteristics of the materials such as color, texture, shape, and weight are emphasized and guide the creation of the works in …


Nonlinear Dynamic Analysis And Control Of Chemical Processes Using Dynamic Operability, San Quan Dinh Jan 2023

Nonlinear Dynamic Analysis And Control Of Chemical Processes Using Dynamic Operability, San Quan Dinh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nonlinear dynamic analysis serves an increasingly important role in process systems engineering research. Understanding the nonlinear dynamics from the mathematical model of a process helps to find the boundaries of all achievable process conditions and identify the system instabilities. The information on such boundaries is beneficial for optimizing the design and formulating a control structure. However, a systematic approach to analyzing nonlinear dynamics of chemical processes considering such boundaries in a quantifiable and adaptable way is yet to exist in the literature. The primary aim of this work is to formulate theoretical concepts for dynamic operability, as well as develop …


Influences On Perceptions Of Students With Disabilities Regarding Services And Supports Rendered At Their Collegiate Institution, Taylor Leanne Mikalik Jan 2023

Influences On Perceptions Of Students With Disabilities Regarding Services And Supports Rendered At Their Collegiate Institution, Taylor Leanne Mikalik

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the past several generations numerous policies and laws have been established that have allowed people with disabilities to further their education. Students with disabilities enter higher education with varied experiences, which allow for a wide array of perceptions of the services and supports provided on this level. The purpose of this dissertation was to study what these perceptions are and how these perceptions were formed; in hopes to encourage more students with disabilities to self-disclose and access beneficial services in the future. A semi-structured narrative interview was conducted with 8 students willing to self-disclose and who received services and …


Pedagogical Piano Works By Four Contemporary Composers: Emma Lou Diemer, Dianne Goolkasian Rahbee, Karen Tanaka And Chee-Hwa Tan, Manuel Alejandro Molina Flores Jan 2023

Pedagogical Piano Works By Four Contemporary Composers: Emma Lou Diemer, Dianne Goolkasian Rahbee, Karen Tanaka And Chee-Hwa Tan, Manuel Alejandro Molina Flores

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research document aims to help diversify the pedagogical piano repertoire by featuring four contemporary composers living in the United States: Emma Lou Diemer, Dianne Goolkasian Rahbee, Karen Tanaka, and Chee-Hwa Tan. Their commitment to the creation of pedagogical works at the elementary, intermediate, and early-advanced levels gives students the opportunity to develop their piano technique while learning beautifully crafted pieces. The present document covers the life, formal education, important influences, and the compositional style of each composer. Additionally, it includes selected pieces at the late-elementary and early-intermediate levels where a discussion about their pedagogical benefits is included. Lastly, a …


Analysis Of ‘Touch’ Dna Recovered From Metal Substrates: An Investigation Into Cfdna-Metal Interactions And The Efficacy Of Different Collection Techniques On Dna Yield, Jessica E. Thornton Jan 2023

Analysis Of ‘Touch’ Dna Recovered From Metal Substrates: An Investigation Into Cfdna-Metal Interactions And The Efficacy Of Different Collection Techniques On Dna Yield, Jessica E. Thornton

Graduate Theses, Dissertations, and Problem Reports (ETD)

While several improvements have been made in recent years to optimize the recovery of ‘touch’ DNA, relatively little research has been conducted to understand the relationship between ‘touch’ DNA and the binding affinity of that DNA to metal surfaces, specifically those with a significant copper presence. Furthermore, characterization of cell-free DNA (cfDNA) and its contribution to ‘touch’ samples and those cfDNA-metal interactions from objects commonly identified at crime scenes (cartridge casings, knives, doorknobs) have been lacking. Research has identified the tendency of copper ions to intercalate with DNA helices, resulting in sample degradation among other damaging conformational changes; however, while …


Multimodal Neuron Classification Based On Morphology And Electrophysiology, Aqib Ahmad Jan 2023

Multimodal Neuron Classification Based On Morphology And Electrophysiology, Aqib Ahmad

Graduate Theses, Dissertations, and Problem Reports (ETD)

Categorizing neurons into different types to understand neural circuits and ultimately brain function is a major challenge in neuroscience. While electrical properties are critical in defining a neuron, its morphology is equally important. Advancements in single-cell analysis methods have allowed neuroscientists to simultaneously capture multiple data modalities from a neuron. We propose a method to classify neurons using both morphological structure and electrophysiology. Current approaches are based on a limited analysis of morphological features. We propose to use a new graph neural network to learn representations that more comprehensively account for the complexity of the shape of neuronal structures. In …


"No, Not There": The Literary Precarity And Profundity Of Queer Spatiality, Samuel James Aftel Jan 2023

"No, Not There": The Literary Precarity And Profundity Of Queer Spatiality, Samuel James Aftel

Theses and Dissertations--English

Love, broadly defined, needs space to grow. For love to materialize and sustain itself (in both literature and society), it must find hospitable geosocial, institutional, and psychic terrain. This is especially true for queer intimacies beyond heteronormative relationality, for the prospect of love’s radical––or reactionary––possibilities is contingent upon the more general sociality in which it develops. Yet love is often a worldmaking and, sometimes, historic mechanism unto itself. Love and its concomitant sexualities must therefore be understood within and without normative structures of hegemony; the workings of (neo)colonialism and capitalism––as well as patriarchy, white supremacy, and heterosexism––dictate to love, and …


Stick With Me: Essays, Clay Shields Jan 2023

Stick With Me: Essays, Clay Shields

Theses and Dissertations--English

A small-town Appalachian deviant confronts the frequent, recurrent grief of the opioid crisis and its mortal, psychological, and communal consequences. This collection endeavors to explore substance use, addiction, geopolitical exploitation of Kentucky, central Appalachia, and surrounding areas, while also celebrating the lives of individual loved ones lost to deaths by suicide, drug overdose, and alcoholism. Here, the common narrative of depravity surrounding addiction is challenged through the rendering of full characters capable of love, trust, friendship, humor, mental health management, and personal growth. Time and place factor fundamentally into the stories told here—whether based in central Kentucky or central Appalachia, …


Economic Comparison Of The Relative Costs And Efficiency Of Using Thermo Fisher Scientific Rapidhit™ Id System Versus Traditional Dna Laboratory Analysis, Paul J. Speaker Jan 2023

Economic Comparison Of The Relative Costs And Efficiency Of Using Thermo Fisher Scientific Rapidhit™ Id System Versus Traditional Dna Laboratory Analysis, Paul J. Speaker

Faculty & Staff Scholarship

With the emergence of any new technology, economic questions arise regarding the efficacy of the new technology in comparison to existing analytical techniques. While the question of ultimate interest concerns the return on investment (ROI) of the new technology, that ROI requires both an evaluation of the net benefits of the technology and an examination of the costs to implement the technology. In this report, we examine the full-loaded cost structure of traditional DNA analysis using fiscal year 2021 data from Project FORESIGHT and compare the cost per sample with the price structure of the Thermo Fischer Scientific RapidHit technology. …


Tennessee Farm Bureau News - January 2023, Tennessee Farm Bureau Federation Jan 2023

Tennessee Farm Bureau News - January 2023, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.


Concluding Remarks By Conference Co-Organizer, Richard H. Weisberg Jan 2023

Concluding Remarks By Conference Co-Organizer, Richard H. Weisberg

Articles

This Article represents the concluding remarks made by Professor Richard H. Weisberg at "Disarmed, Distracted, Disconnected & Distressed," a conference on Modern Legal Education and the Unmaking of American Lawyers, hosted by the University of Pittsburgh School of Law and the Law & Humanities Institute, April 20-April 23, 2023.


Room-Temperature Crystallography Reveals Altered Binding Of Small-Molecule Fragments To Ptp1b, Tamar Skaist Mehlman, Justin T. Biel, Syeda Maryam Azeem, Elliot R. Nelson, Sakib Hossain, Louise Dunnett, Neil G. Paterson, Alice Douangamath, Romain Talon, Danny Axford, Helen Orins, Frank Von Delft, Daniel A. Keedy Jan 2023

Room-Temperature Crystallography Reveals Altered Binding Of Small-Molecule Fragments To Ptp1b, Tamar Skaist Mehlman, Justin T. Biel, Syeda Maryam Azeem, Elliot R. Nelson, Sakib Hossain, Louise Dunnett, Neil G. Paterson, Alice Douangamath, Romain Talon, Danny Axford, Helen Orins, Frank Von Delft, Daniel A. Keedy

Advanced Science Research Center

Much of our current understanding of how small-molecule ligands interact with proteins stems from X-ray crystal structures determined at cryogenic (cryo) temperature. For proteins alone, room-temperature (RT) crystallography can reveal previously hidden, biologically relevant alternate conformations. However, less is understood about how RT crystallography may impact the conformational landscapes of protein-ligand complexes. Previously, we showed that small-molecule fragments cluster in putative allosteric sites using a cryo crystallographic screen of the therapeutic target PTP1B (Keedy et al., 2018). Here, we have performed two RT crystallographic screens of PTP1B using many of the same fragments, representing the largest RT crystallographic screens of …


“A Plague Broke Out Among Them”: Reflections On The Bible And The Pandemic, Joel Kaminsky Jan 2023

“A Plague Broke Out Among Them”: Reflections On The Bible And The Pandemic, Joel Kaminsky

Religion: Faculty Publications

This essay seeks to utilize ideas and texts found in the Hebrew Bible in order to historically contextualize the COVID-19 pandemic and to illuminate various existential, religious, political, and ethical issues raised by the current pandemic and our responses to it.


2023 Conference Schedule, Georgia Southern University Jan 2023

2023 Conference Schedule, Georgia Southern University

SoTL Commons Conference

Virtual Schedule Link: https://sotlcommons2023.sched.com/


Editorial: Perspectives On Ptsd And Its Treatment, Jacklynn M. Fitzgerald, Ashley A. Huggins Jan 2023

Editorial: Perspectives On Ptsd And Its Treatment, Jacklynn M. Fitzgerald, Ashley A. Huggins

Psychology Faculty Research and Publications

No abstract provided.


Editorial: Insights In Neurocognitive Aging And Behavior: 2021, Kristy A. Nielson, Ian M. Mcdonough, Anja Soldan Jan 2023

Editorial: Insights In Neurocognitive Aging And Behavior: 2021, Kristy A. Nielson, Ian M. Mcdonough, Anja Soldan

Psychology Faculty Research and Publications

In recent years, exceptional scientific achievements have led to major advancements in the fast-growing field of neurocognitive aging and behavior. In this inaugural collection, Insights in Neurocognitive Aging and Behavior: 2021, we sought to highlight the latest advancements and challenges for the current state of knowledge and future directions in aging neuroscience in the neurocognitive arena. Here we outline the contributions and implications for future research of the 15 papers in this topic collection across four important research areas: (1) novel approaches to identifying and tracking brain aging and impending cognitive decline; (2) neurocognitive markers of risks for Alzheimer’s disease …


Large-Scale Network Connectivity And Cognitive Function Changes After Exercise Training In Older Adults With Intact Cognition And Mild Cognitive Impairment, Junyeon Won, Kristy A. Nielson, J. Carson Smith Jan 2023

Large-Scale Network Connectivity And Cognitive Function Changes After Exercise Training In Older Adults With Intact Cognition And Mild Cognitive Impairment, Junyeon Won, Kristy A. Nielson, J. Carson Smith

Psychology Faculty Research and Publications

Background:

Despite growing evidence regarding the association between exercise training (ET) and functional brain network connectivity, little is known about the effects of ET on large-scale within- and between-network functional connectivity (FC) of core brain networks.

Objective:

We investigated the effects of ET on within- and between-network functional connectivity of the default mode network (DMN), frontoparietal network (FPN), and salience network (SAL) in older adults with intact cognition (CN) and older adults diagnosed with mild cognitive impairment (MCI). The association between ET-induced changes in FC and cognitive performance was examined.

Methods:

33 older adults (78.0±7.0 years; 16 MCI and 17 …


High Impact Practices: Faculty Perceptions And Barriers To Implementation, Virginia (Ginger) B. Wickline, Rami Haddad, Padmini Shankar, Karelle Aiken Jan 2023

High Impact Practices: Faculty Perceptions And Barriers To Implementation, Virginia (Ginger) B. Wickline, Rami Haddad, Padmini Shankar, Karelle Aiken

SoTL Commons Conference

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Editorial: Microglia In Neuroinflammation, Pinar Ayata, Ido Amit, Carla M. Cuda Jan 2023

Editorial: Microglia In Neuroinflammation, Pinar Ayata, Ido Amit, Carla M. Cuda

Advanced Science Research Center

Microglia are a resident innate immune cell population of the central nervous system (CNS) derived from yolk sac erythro-myeloid progenitors that migrate to the developing brain prior to the formation of the blood-brain barrier. This critical cell population has gained considerable traction in the literature as it is considered a protective barrier from CNS damage and, yet, can also serve as a primary mediator of neuroinflammation. Under normal physiological conditions, microglia perform homeostatic functions, such as parenchymal surveillance, neurotrophic support, pathogen or debris removal, and maintenance of synaptic homeostasis and neuronal plasticity.


The Lead, January 2023, Lindenwood University Jan 2023

The Lead, January 2023, Lindenwood University

The Lead

The Lead is an electronic newsletter produced by the Lindenwood College of Education & Human Services.


Issue Of Data Imbalance On Low Birthweight Baby Outcomes Prediction And Associated Risk Factors Identification: Establishment Of Benchmarking Key Machine Learning Models With Data Rebalancing Strategies, Yang Ren, Dezhi Wu, Yan Tong, Ana Lopez-De Fede Jan 2023

Issue Of Data Imbalance On Low Birthweight Baby Outcomes Prediction And Associated Risk Factors Identification: Establishment Of Benchmarking Key Machine Learning Models With Data Rebalancing Strategies, Yang Ren, Dezhi Wu, Yan Tong, Ana Lopez-De Fede

Publications

Background: Low birthweight (LBW) is a leading cause of neonatal mortality in the United States and a major causative factor of adverse health effects in newborns. Identifying high-risk patients early in prenatal care is crucial to preventing adverse outcomes. Previous studies have proposed various machine learning (ML) models for LBW prediction task, but they were limited by small and imbalanced data sets. Some authors attempted to address this through different data rebalancing methods. However, most of their reported performances did not reflect the models’ actual performance in real-life scenarios. To date, few studies have successfully benchmarked the performance of ML …


Association Of Hospital Incentive Care Management Partnerships For Uninsured Patients With Emergency Department Utilization, Sarah Gareau, Ana Lopez-De Fede, Zhimin Chen, Nathaniel Bell Jan 2023

Association Of Hospital Incentive Care Management Partnerships For Uninsured Patients With Emergency Department Utilization, Sarah Gareau, Ana Lopez-De Fede, Zhimin Chen, Nathaniel Bell

Publications

IMPORTANCE The South Carolina (SC) Healthy Outcomes Plan (HOP) program aimed to expand access to health care to individuals without insurance; it remains unknown whether there is an association between the SC HOP program and emergency department (ED) use among patients with high health care costs and needs. OBJECTIVES To determine whether participation in the SC HOP was associated with reduced ED utilization among uninsured participants. DESIGN, SETTING, AND PARTICIPANTS This retrospective cohort study included 11 684 HOP participants (ages 18-64 years) with at least 18 months of continuous enrollment. Generalized estimating equations and segmented regression of interrupted time-series analyses …


Qualitative Analysis Of Anti-Abortion Discourse Used In Arguments For A 6-Week Abortion Ban In South Carolina, Victoria C. Lambert, Emily E. Hackworth, Deborah Lynn Billings Phd Jan 2023

Qualitative Analysis Of Anti-Abortion Discourse Used In Arguments For A 6-Week Abortion Ban In South Carolina, Victoria C. Lambert, Emily E. Hackworth, Deborah Lynn Billings Phd

Publications

Background: On June 24, 2022, The U.S. Supreme Court overturned Roe v. Wade, leaving abortion legislation entirely up to states. However, anti-abortion activists and legislators have organized for decades to prevent abortion access through restrictive state-level legislation. In 2019, South Carolina legislators proposed a bill criminalizing abortion after 6 weeks gestation, before most people know they are pregnant. The current study examines the anti-abortion rhetoric used in legislative hearings for this extreme abortion restriction in South Carolina. By examining the arguments used by anti-abortion proponents, we aim to expose their misalignment with public opinion on abortion and demonstrate that their …


Front Pages Jan 2023

Front Pages

Oklahoma Law Review

No abstract provided.


Necessary Necessity: Courts’ Historical Assessment Of The Condition Precedent For Martial Law, Eric Merriam Jan 2023

Necessary Necessity: Courts’ Historical Assessment Of The Condition Precedent For Martial Law, Eric Merriam

Oklahoma Law Review

No abstract provided.


The Server Test Quandary And Embedding Permission Culture, Michael P. Goodyear Jan 2023

The Server Test Quandary And Embedding Permission Culture, Michael P. Goodyear

Oklahoma Law Review

No abstract provided.