Digital Commons Network^™

Career Transitioning Among Students With Visual Impairments: Educational And Public Policy Perspectives, Chiedu Eseadi, Shulamite E. Ogbuabor

Jurnal Kajian Bimbingan dan Konseling

The objective of this research is to examine the educational and public policy concerns pertaining to career transitioning among students with visual impair-ments. The authors conducted a narrative literature review. The conceptualization of policy, with a specific focus on educational and public policies, was provided. The article also discussed the roles and concerns of educational and public policies in facilitating career transitioning for these students. The study contributes to an increased understanding of the educational and policy implications of supporting students with visual impairments during career transitioning. The collaboration of career counsellors and policy actors is deemed necessary in order …

Classification Of Colon Cancer Patients Into Consensus Molecular Subtypes Using Support Vector Machines, Necla Koçhan, Baris Emre Dayanc

Turkish Journal of Biology

Background/aim: The molecular heterogeneity of colon cancer has made classification of tumors a requirement for effective treatment. One of the approaches for molecular subtyping of colon cancer patients is the Consensus Molecular Subtypes (CMS) developed by the Colorectal Cancer Subtyping Consortium (CRCSC). CMS-specific RNA-Seq dependent classification approaches are recent with relatively low sensitivity and specificity. In this study, we aimed to classify patients into CMS groups using RNA-seq profiles. Materials and methods: We first identified subtype specific and survival associated genes using Fuzzy C-Means (FCM) algorithm and log-rank test. Then we classified patients using Support Vector Machines with Backward Elimination …

Evolution Of Primate Vocal Repertoires: Vocal Systems As Embodied Capital For Mediating Within-Group Conflict, Eric Schniter, Mateo Peñaherrera-Aguirre

ESI Working Papers

Life history traits constrain investments in costly neural and somatic embodied capital, potentially shaping the evolution of primate vocal communication systems. This study integrates life history theory with the social complexity hypothesis to test a sequential pathway from longevity to social dynamics to vocal repertoire size, using updated vocal repertoire data for McComb & Semple’s (2005) set of 42 non-human primate species, alongside measures of group size and within-group conflict. We compiled data on vocal repertoire size, within-group conflict, group size, endocranial volume, and maximum longevity, analysing these via Phylogenetic Sequential Canonical Cascade Model and ancestral character reconstructions. …

Pre-Service Teachers’ Experiences With Multi-Tiered Systems Of Support: Universal Screening & Intervention Planning, Alexandra J. Taylor, Tommy Wells, Amy Lein

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Assessment plays a key role in the multi-tiered system of support (MTSS) model. Universal screening is an assessment component embedded into MTSS, specifically within the response to intervention framework. The process of administering, scoring, and analyzing data from a universal screener is an essential skill that pre-service teachers need to gain in their educator preparation programs. In this qualitative, case study approach, we examined the ways an experimental learning project in implementing universal screeners impact pre-service teachers’ beliefs and practices for Tier 1 of MTSS. The project was provided to pre-service teachers to give them familiarization with the implementation of …

Genital Tract Infections, The Vaginal Microbiome And Gestational Age At Birth Among Pregnant Women In South Africa: A Cohort Study Protocol, Ranjana M.S. Gigi, Mandisa M. Mdingi, Hyunsul Jung, Shantelle Claassen-Weitz, Lukas Bütikofer, Jeffrey D. Klausner, Christina A. Muzny, Christopher M. Taylor, Janneke H.H.M. Van De Wijgert, Remco P.H. Peters, Nicola Low

School of Medicine Faculty Publications

Introduction Preterm birth complications are the most common cause of death in children under 5 years. The presence of multiple microorganisms and genital tract inflammation could be the common mechanism driving early onset of labour. South Africa has high levels of preterm birth, genital tract infections and HIV infection among pregnant women. We plan to investigate associations between the presence of multiple lower genital tract microorganisms in pregnancy and gestational age at birth. Methods and analysis This cohort study enrols around 600 pregnant women at one public healthcare facility in East London, South Africa. Eligible women are ≥18 years and …

School Environment As Barrier To Effective Academic Performance Among Students With Physical Disabilities In Ilorin Metropolis, Florence Bosede Famolu

Jurnal Kajian Bimbingan dan Konseling

Insufficient infrastructural facilities make it difficult for a large number of students with visual and mobility impairment to walk around the campus and attend lectures. Also, fewer than ideal library facilities decrease the amount of study resources that are available to these students. This study investigated the school environment as barrier to effective academic performance among students with physical disabilities in the Ilorin metropolis, Kwara State. The descriptive survey of a correlational type was implemented using purposive sampling for this study. A purposive sampling technique was used to select 98 students in the Ilorin metropolis with physical disabilities, and the …

Measuring The Difficulties Of Early Adulthood: The Development Of The Quarter Life Crisis Scale, Muslim Afandi, Nail Hidaya Afandi, Syed Agung Afandi, Rizki Erdayani

Jurnal Kajian Bimbingan dan Konseling

This study was conducted to develop a quarter-life crisis scale that can be used to measure the quarter-life crisis of early adulthood in Indonesia. Although it has begun to become a concern for researchers in Indonesia, the development of the quarter-life crisis scale has never been created. Some researchers have adapted the constructs developed by foreign researchers, which are not necessarily suitable for applicated in Indonesia. The development of this scale goes through 5 stages: conceptualization of the test; test construction; test trial; item analysis; and test revision. The test trial was filled by 181 early adults in Indonesia from …

Information Behavior And Hiv/Aids/Sti Awareness Among Bangladeshi Female Sex Workers: Do Informational Programs Help?, Nafiz Z. Shuva, Radia Taisir, Parvez Sazzad Mallick

Publications and Research

Using de Certeau's concepts of “tactics” and “strategies,” this study explores the everyday information seeking behavior of female sex workers (FSWs) in Bangladesh. This study also examined the effectiveness of informational programs on HIV/AIDS and STI in empowering FSWs to negotiate condom use during sex. A mixed method research design was employed in this study, which included face-to-face surveys with 116 female sex workers (FSWs) and four focus group discussions (FGDs) with 23 street based FSWs. The study finds that Bangladeshi female sex workers use “tactics” in meeting their information needs. They reported rarely using formal information sources such as …

Svm-Do: Identification Of Tumor-Discriminating Mrna Signatures Via Support Vectormachines Supported By Disease Ontology, Mustafa Erhan Özer, Pemra Özbek Sarica, Kazim Yalçin Arğa

Turkish Journal of Biology

Background/aim: The complicated nature of tumor formation makes it difficult to identify discriminatory genes. Recently, transcriptome-based supervised classification methods using support vector machines (SVMs) have become popular in this field. However, the inclusion of less significant variables in the construction of classification models can lead to misclassification. To improve model performance, feature selection methods such as enrichment analysis can be used to extract useful variable sets. The detection of genes that can discriminate between normal and tumor samples in the association of cancer and disease remains an area of limited information. We therefore aimed to discover novel and practical sets …

Compcorona: A Web Application For Comparative Transcriptome Analyses Ofcoronaviruses Reveals Sars-Cov-2-Specific Host Response, Rana Sali̇hoğlu, Fati̇h Saraçoğlu, Mustafa Si̇bai̇, Tali̇p Zengi̇n, Başak Abak Masud, Onur Karasoy, Tuğba Önal Süzek

Turkish Journal of Biology

Background/aim: Understanding the mechanism of host transcriptomic response to infection by the SARS-CoV-2 virus is crucial, especially for patients suffering from long-term effects of COVID-19, such as long COVID or pericarditis inflammation, potentially linked to side effects of the SARS-CoV-2 spike proteins. We conducted comprehensive transcriptome and enrichment analyses on lung and peripheral blood mononuclear cells (PBMCs) infected with SARS-CoV-2, as well as on SARS-CoV and MERS-CoV, to uncover shared pathways and elucidate their common disease progression and viral replication mechanisms. Materials and methods: We developed CompCorona, the first interactive online tool for visualizing gene response variance among the family …

Stemnesscore: An R Package To Estimate The Stemness Of Glioma Cancer Cells At Single-Cell Resolution, Necla Koçhan, Yavuz Oktay, Gökhan Karakülah

Turkish Journal of Biology

Background/aim: Glioblastoma is the most heterogeneous and the most difficult-to-treat type of brain tumor and one of the deadliest among all cancers. The high plasticity of glioma cancer stem cells and the resistance they develop against multiple modalities of therapy, along with their high heterogeneity, are the main challenges faced during treatment of glioblastoma. Therefore, a better understanding of the stemness characteristics of glioblastoma cells is needed. With the development of various single-cell technologies and increasing applications of machine learning, indices based on transcriptomic and/or epigenomic data have been developed to quantitatively measure cellular states and stemness. In this study, …

Suma: A Lightweight Machine Learning Model Powered Shared Nearest Neighbour Based Clustering Application Interface Of Scrna-Seq, Hamza Umut Karakurt, Pınar Pir

Turkish Journal of Biology

Background/aim: Single-cell transcriptomics (scRNA-Seq) explores cellular diversity at the gene expression level. Due to the inherent sparsity and noise in scRNA-Seq data and the uncertainty on the types of sequenced cells, effective clustering and cell type annotation are essential. The graph-based clustering of scRNA-Seq data is a simple yet powerful approach which presents data as a “shared nearest neighbour” graph and clusters the cells using graph clustering algorithms. These algorithms are dependent on several user-defined parameters. Here we present SUMA, a lightweight tool that uses a random forest model to predict the optimum number of neighbours to have the optimum …

Physicochemical Differences Between Camelid Single-Domain Antibodies And Mammalian Antibodies, Nazli Eda Eski̇er, Doğa Eski̇er, Esi̇n Fi̇ruzan, Si̇bel Kalyoncu

Turkish Journal of Biology

Background/aim: In recent years, single-domain antibodies, also known as nanobodies, have emerged as an alternative to full immunoglobulin Gs (IgGs), due to their various advantages including increased solubility, faster clearance, and cheaper production. Nanobodies are generally derived from the variable domain of the camelid heavy-chain-only immunoglobulin Gs (hcIgGs). Due to the high sequence homology between variable heavy chains of camelids (VHHs) and humans (VHs), hcIgGs are ideal candidates for nanobody development. However, further examination is needed to understand the structural differences between VHs and VHHs. This analysis is essential for nanobody engineering to mitigate potential immunogenicity while preserving stability, functionality, …

Shan Song Xiao / 山松晓, 熙福 著, Jane Li

Zea E-Books Collection

故事梗概 这本书描写一百年来一家三代女儿的家族故事，从外祖母，母亲，再到女儿，她们生活在有重叠的生活里，又各自有着不同时代不同主旋律的生活轨迹。光阴荏苒，人生匆匆，回首过往，记录生活。 书中的人物以真实人物为原型，作者将真实名字略去，并在故事情节上加以了丰富和构想。 作者：熙福

ShanSongXiao 'Morning Pine on the Mountain' -- Summary of the story: This book describes the family story of three generations of daughters in a family over the past 100 years. From grandmother, mother, to daughter, they live in overlapping lives, and each has a life trajectory with different themes in different times. Time flies, life is in a hurry, look back on the past and record life. The characters in the book are based on real people. The author has omitted their real names and enriched and imagined the storyline. Author: Xi Fu

部分读后感： 你的小说语言淳朴，接地气。我非常喜欢你的小说，看过后有很多感想。一代一代的 女性不容易，我们赶上了好时代，要争取自己的权力！~ …

Ai-Enabled Assessment Of Roadway Integrity: Forecasting Bitumen Deformation And Road Stability Throughout The Lifecycle Under Traffic Impact, Sabahudin Vrtagic, Milan Dordevic, Fatih Dogan, Muhammed Codur, Mario Hoxha, Edis Softic

Materials Science and Engineering Faculty Research & Creative Works

Asphalt-paved Road junctions frequently encounter deformation and degradation challenges due to heavy vehicular traffic and varying climatic conditions, such as temperature fluctuations and precipitation. This study employs a multifaceted approach, incorporating a Multilayer Perceptron (MLP) model, ancillary machine learning techniques, and optimization methodologies, to address these challenges effectively. The primary objectives are the prediction and analysis of pavement deformation, the optimization of maintenance strategies, and the evaluation of road effectiveness. Our findings underscore the substantial contribution of heavy vehicles to road erosion and the profound impact of vehicular retention and braking at intersections. A Multilayer Perceptron (MLP) model is utilized …

Amondys 45 (Casimersen), A Novel Antisense Phosphorodiamidate Morpholino Oligomer: Clinical Considerations For Treatment In Duchenne Muscular Dystrophy, Megan E. Vasterling, Rebecca J. Maitski, Brice A. Davis, Julie E. Barnes, Rucha A. Kelkar, Rachel J. Klapper, Hirni Patel, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye, Giustino Varrassi

School of Medicine Faculty Publications

AMONDYS 45 (casimersen) is an antisense oligonucleotide therapy used to treat Duchenne muscular dystrophy (DMD), a rare genetic disorder characterized by a mutation in the DMD gene. Symptoms include progressive muscle weakness, respiratory and cardiac complications, and premature death. Casimersen targets a specific mutation in the DMD gene that results in the absence of dystrophin protein, a key structural component of muscle fibers. While there is currently no cure for DMD, exon-skipping therapy works by restoring the reading frame of the mutated gene, allowing the production of a partially functional dystrophin protein. Clinical trials of casimersen have shown promising results …

Matter Of Promenade Nelson Apts., Llc V. New York State Div. Of Hous. & Community Renewal

All Decisions

No abstract provided.

Deron Brunson Appellant V. Anthony B. Anderson Appellee : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

This appeal taken from a final Judgment and Order in the Third Judicial District Court, Salt Lake County, State of Utah, from the Honorable James Gardner.

Anthony B. Anderson, Appellee, pro se

Deron Brunson, Appellant, pro se

Analysis Of Potentially Inappropriate Prescriptions (Pip) Based On Stopp/Start Criteria In Geriatric Patients With Cardiovascular Disorders At Hasan Sadikin Hospital, Bandung, West Java, Indonesia, Fathurrahmi Fathurrahmi, Gofarana Wilar, Jutti Levita, Rina Winarni

Pharmacology and Clinical Pharmacy Research

The geriatric population in Indonesia is increasing rapidly every year. The large number of drugs consumed by geriatric patients results in potentially inappropriate prescriptions (PIP) in the form of mis-prescribing drugs (potentially inappropriate medicines or PIM) and under-prescribing drugs (potentially prescription omission or PPO). In Indonesia, especially in Bandung, there is limited research on PIP in geriatric patients with cardiovascular disorders (CVDs). This study aims to identify PIP and factors that influence PIM and PPO based on STOPP/START criteria and the relationship between the incidence of PIM and kidney function in geriatric inpatients with CVDs at Hasan Sadikin Hospital, Bandung, …

License Revoked For Fatal Injury, Ross Sandler

Other Publications

No abstract provided.

Deep Change Theory: Implications For Educational Development Leaders, Caitlin Martin, Elizabeth Wardle

Publications

While chapters 1 and 2 explore the promise of theoretical frameworks for making conceptual change that leads to innovative action around teaching and learning in higher education, they also point out the challenges to this kind of work as teams of faculty strive to lead change in their programs and departments after completing the program. To summarize our claims thus far: one of the goals for the HCWE Faculty Writing Fellows Program is to empower faculty who participate to return to their departments to make programmatic changes—changes they identify as central to their work and values and program culture. The …

Front Matter, Naya Sucha-Xaya

Journal of Letters

No abstract provided.

Analogy, Concept And Cognition, Kanit (Mitinunwong) Sirichan

Journal of Letters

This research paper aims to study analogy as a type of comparative thinking and to investigate whether it is justified to claim that an analogical thought has cognitive content. Two theories in cognitive science claim that an analogy has cognitive content. The first one is called the weak view of analogy in cognition; this is expressed in, for example, the works of Gust et al. (2008), Lakoff & Johnson (1980), Hesse (1966), and Black (1955). The second one is called the strong view of analogy in cognition, seen, for example, in the works of Hofstadter (2001, 2006) and Hofstadter and …

Infernal Symbioses: Reading Dante’S Inferno In The Chthulucene, Rawitawan Sophonpanich

Journal of Letters

This article explores the possibility of foregrounding Dante’s Inferno from the epic La Divina Commedia in this day and age of environmental crises. This catastrophic state has androgenic origins and has been labeled by climate scientists as the “Anthropocene” – a new geological era marked by the ways in which humanity has irrevocably altered the earth system. Nevertheless, Donna Haraway has voiced her opposition against this classification, postulating that it contains too much nihilistic and pessimistic connotations that function to discourage humans from doing the work necessary to alleviate the crises. Haraway therefore proposes “Chthulucene” to denote the temporally and …

Comparative Conceptual Metaphors In Thai Politics: A Case Study Before The Elections In 2001, 2007, And 2023, Theewara Saengin

Journal of Letters

The changes in Thailand’s electoral system over a period of more than 20 years have influenced the use of language that reflects the perspectives of people in Thai society. This article aims to (1) study Thai political metaphors before the 2023 elections in political analysis articles in the ThaiRath online newspaper between October 1 and December 31, 2022, and (2) compare Thai political metaphors before the 2023 elections with those in 2001 and 2007 using a conceptual metaphor framework for comparing one thing to another through a process of mapping meaning from a source domain to a target domain, as …

T. M. Scanlon On Normativity: A Methodological Exploration, Piyarudee Chaiyaporn

Journal of Letters

This article argues that T. M. Scanlon’s account of normativity, grounded in the concepts of reasons and reason relations, is strongly justified as it attains substantive coherence through the method of reflective equilibrium. The argument focuses on three strategies employed by Scanlon in his critical analysis of Joseph Raz’s and Jonathan Dancy’s alternative accounts of normativity, namely, (1) characterization, (2) the pursuit of narrow reflective equilibrium (N-RE), and (3) the pursuit of wide reflective equilibrium (W-RE). In addition to the robustness provided by substantive coherence, which safeguards his account against Justin Clarke-Doane’s objection regarding reliability, Scanlon is also able to …

Psychological Well-Being Of Pre-Service Training Teachers, Indriyana Rachmawati, Aprilia Tina Lidyasari

Jurnal Kajian Bimbingan dan Konseling

The recent statistic suggests the average psychological well-being of Indonesian citizens, including the pre-service training teacher, represents their capacity to overcome future challenges. Excellent psychological well-being is crucial for pre-service training teachers, especially for providing a comfortable learning situation for students and engaging in effective communication with students. This study investigates the psychological well-being of pre-service training teachers. Thus, this study adopted survey techniques with descriptive data analysis. The data were collected from 44 teachers selected by purposive sampling. The criteria for selecting research participants were currently taking pre-service teacher education, elementary school teachers, and willingness to participate in this …

Education And Work Future Expectation Scale Adaptation For Indonesian University Students, Ike Dwiastuti, Wiwin Hendriani, Fitri Andriani

Jurnal Kajian Bimbingan dan Konseling

The students' optimism about their future careers and education impacts their educational success. The Future Expectation Scale of Adolescents (FESA) can measure future expectations of education and student career. This study aims to adapt the scale of the FESA work and education domain to the Indonesian language and culture. The adaptation in this study follows the six-stage category of the International Commission Test. Development of adaptation items using a forward-backward translation design involving six experts. The comparability of language and content validity assessments involved nine experts. Pilot study for item evaluation involving 15 students from the target population. The quantitative …

Patient-Reported Sexual Function, Bladder Function And Quality Of Life For Patients With Low Rectal Cancers With Or Without A Permanent Ostomy, Michael K Rooney, Melisa Pasli, George J Chang, Prajnan Das, Eugene J Koay, Albert C Koong, Ethan B Ludmir, Bruce D Minsky, Sonal S Noticewala, Oliver Peacock, Grace L Smith, Emma B Holliday

Faculty, Staff and Student Publications

BACKGROUND: Despite the increasing utilization of sphincter and/or organ-preservation treatment strategies, many patients with low-lying rectal cancers require abdominoperineal resection (APR), leading to permanent ostomy. Here, we aimed to characterize overall, sexual-, and bladder-related patient-reported quality of life (QOL) for individuals with low rectal cancers. We additionally aimed to explore potential differences in patient-reported outcomes between patients with and without a permanent ostomy.

METHODS: We distributed a comprehensive survey consisting of various patient-reported outcome measures, including the FACT-G7 survey, ICIQ MLUTS/FLUTS, IIEF-5/FSFI, and a specific questionnaire for ostomy patients. Descriptive statistics and univariate comparisons were used to compared demographics, treatments, …

Social Determinants Of Health And Disparities In Hypertension And Cardiovascular Diseases, Abhishek Chaturvedi, Anqi Zhu, Naga Vaishnav Gadela, Dorairaj Prabhakaran, Tazeen Jafar

Department of Medicine

High blood pressure causes over 10 million preventable deaths annually globally. Populations in low- and middle-income countries suffer the most, experiencing increased uncontrolled blood pressure and cardiovascular disease (CVD) deaths. Despite improvements in high-income countries, disparities persist, notably in the United States, where Black individuals face up to 4× higher CVD mortality than White individuals. Social determinants of health encompass complex, multidimensional factors linked to an individual's birthplace, upbringing, activities, residence, workplaces, socioeconomic and environmental structures, and significantly affect health outcomes, including hypertension and CVD. This review explored how social determinants of health drive disparities in hypertension and related CVD …