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2023

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Alpha-Cyclodextrin-Containing Beverages For Hydration Enhancement In Humans, Ethan G. Tinoco, Madelin Siedler, Christian Rodriguez, Sarah White, Gabrielle Dehaven, Alexandra Brojanac, Patrick Harty, Matthew Stratton, Jacob Green, Jake Boykin, Abegale Williams, Grant M. Tinsley, Dale Keith Feb 2023

Alpha-Cyclodextrin-Containing Beverages For Hydration Enhancement In Humans, Ethan G. Tinoco, Madelin Siedler, Christian Rodriguez, Sarah White, Gabrielle Dehaven, Alexandra Brojanac, Patrick Harty, Matthew Stratton, Jacob Green, Jake Boykin, Abegale Williams, Grant M. Tinsley, Dale Keith

International Journal of Exercise Science: Conference Proceedings

A substantial portion of the world’s population may be inadequately hydrated, and dehydration is associated with several disease states and acute impairments in exercise performance. As such, there is continued interest in novel strategies to promote adequate hydration. The carbohydrate alpha-cyclodextrin has recently been shown to enhance water uptake through human aquaporins expressed in a single-cell model and promote longevity in model multicellular organisms. However, there is no relevant human research examining the potential hydrating effects of alpha-cyclodextrin-containing beverages. PURPOSE: To determine if novel beverage formulations containing alpha-cyclodextrin improve a bioimpedance-based hydration marker in humans. METHODS: In a …


The Effects Of Acute Fasting On Anaerobic Performance In Naia Softball Players, Emily J. Sauers, Madison A. Garza, Jennifer M. Estrada Feb 2023

The Effects Of Acute Fasting On Anaerobic Performance In Naia Softball Players, Emily J. Sauers, Madison A. Garza, Jennifer M. Estrada

International Journal of Exercise Science: Conference Proceedings

Intermittent fasting has become a popular method for athletes to help manage body weight. Additionally, athletes with early morning athletic practice often omit breakfast and arrive in a fasted state. It is unclear how fasting impacts performance in softball players. PURPOSE: The purpose of this study was to evaluate anaerobic performance in NAIA Softball players following an overnight fast. METHODS: Eight NAIA female softball players participated in this randomized cross-over study. Athletes were on the active roster at Our Lady of the Lake University. Athletes were 20.7 ± 0.5 years old, 163.1 ± 2.1 cm tall, 151.5 ± 10.0 lb. …


Physiological Stress Responses To A Live-Fire Training Evolution In Career Firefighters, Drew E. Gonzalez, Sarah E. Johnson, Courtney C. Dillard, Ryan J. Sowinski, Steven E. Martin, Lisa C. Colvin, Matthew J. Mcallister Feb 2023

Physiological Stress Responses To A Live-Fire Training Evolution In Career Firefighters, Drew E. Gonzalez, Sarah E. Johnson, Courtney C. Dillard, Ryan J. Sowinski, Steven E. Martin, Lisa C. Colvin, Matthew J. Mcallister

International Journal of Exercise Science: Conference Proceedings

Firefighters have a physically demanding job that exposes them to many specific and unique stressors, which contribute to cardiovascular disease (CVD) risk (i.e., cardiovascular strain, inflammation, and oxidative stress) or even mortality. At present, the literature lacks data evaluating these physiological stress responses amongst firefighters in any realistic or simulated scenarios, such as a live-fire training evolution (LFTE). Given the elevated risk of premature mortality, there is a critical need to better understand the physiological stress responses to an LFTE. This information could aid in developing nutritional, training, and other various interventions to mitigate stress load and reduce the incidence …


Sacral Stress Fracture — Wrestling, Billal Siddiq, Nikolaos Gravvanis, Charalampos Kyratzoglou, Brett Hayes, Andreas Stamatis Feb 2023

Sacral Stress Fracture — Wrestling, Billal Siddiq, Nikolaos Gravvanis, Charalampos Kyratzoglou, Brett Hayes, Andreas Stamatis

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: During preseason, a 35-year-old wrestler complained of pain in his lower back concurrently with a tingling sensation in the left thigh and buttocks. PHYSICAL EXAM: The wrestler was examined by a physical therapist (PT) and, while discussing prior medical history, the athlete mentioned a previous diagnosis of a mild herniated disk (Grade 1). Upon clinical examination, the athlete demonstrated a full range of motion with some discomfort in passive hip extension. The PT suggested rest and rehabilitation through electrical stimulation, alongside the strengthening of the lumbar spine and hip abductor muscles. Ten days later, the athlete …


Sublingual Caffeine Supplementation And Its Effects On Physical Performance Measures In Highly Fit United States Military Personnel, Reggie B. O'Hara Feb 2023

Sublingual Caffeine Supplementation And Its Effects On Physical Performance Measures In Highly Fit United States Military Personnel, Reggie B. O'Hara

International Journal of Exercise Science: Conference Proceedings

Caffeine is a commonly used countermeasure to combat sleep deprivation and alleviate physiological and psychological performance degradations in highly trained military personnel operating in extreme environments for extending periods. Although the mechanisms of action of caffeine are well described in the literature, the ergogenic effects of caffeine are variable based on the individual’s nutritional status, sensitivity to caffeine, genetics, dose, timing, and overall physical condition. PURPOSE: To explore the effects of moderate doses of sublingual caffeine on physical performance measures and perceptions of fatigue in highly fit U.S. military personnel. METHODS: A convenience sample of eleven highly trained, …


Recent Developments In Methods To Characterise The Chemical And Biological Parameters Of Grass Silage, R. S. Park, R. E. Agnew, M. G. Porter Feb 2023

Recent Developments In Methods To Characterise The Chemical And Biological Parameters Of Grass Silage, R. S. Park, R. E. Agnew, M. G. Porter

IGC Proceedings (1977-2023)

Key points

  1. Chemical analysis of forages is expensive, time consuming, environmentally unfriendly and relates poorly to the feed value for production purposes.
  2. In vivo characterisation of animal feed is not a feasible option in terms of cost and analysis time.
  3. NIRS is a rapid, non destructive, environmentally friendly, multi-analytical technique which can estimate the nutritive value of the feed.
  4. NIRS predictive equations developed on a master instrument can be transferred to local and international sites.
  5. Future assessment of forages necessitates rapid, stable, instrumentation for ‘in field’ studies.


The Effect Of Chop Length And Additive On Silage Intake And Milk Production In Cows, V. Toivonen, T. Heikkilä Feb 2023

The Effect Of Chop Length And Additive On Silage Intake And Milk Production In Cows, V. Toivonen, T. Heikkilä

IGC Proceedings (1977-2023)

Effects of reduced silage chop length on silage intake and milk production by dairy cows have been variable. Chopping of grass at harvest generally improves silage fermentation quality and consequently intake. The objective of this study was to assess the effect of chopping flail harvested silage ensiled with acid or biological additive prior to feeding on intake, milk yield and milk composition in dairy cows.


Effect Of Additives At Harvest On The Digestibility In Lambs Of Whole Crop Barley Or Wheat Silage, S. Muhonen, I. Olsson, P. Lingvall Feb 2023

Effect Of Additives At Harvest On The Digestibility In Lambs Of Whole Crop Barley Or Wheat Silage, S. Muhonen, I. Olsson, P. Lingvall

IGC Proceedings (1977-2023)

There are very few published articles about how silage additives affect digestibility of whole crop silage. In this experiment, male lambs were given whole crop barley or wheat silage harvested at dough stage with a number of different acid-based and bacterial additives.


Use Of Silage Additives In Ensiling Of Whole-Crop Barley And Wheat - A Comparison Of Round Big Bales And Precision Chopped Silages, M. Knický, P. Lingvall Feb 2023

Use Of Silage Additives In Ensiling Of Whole-Crop Barley And Wheat - A Comparison Of Round Big Bales And Precision Chopped Silages, M. Knický, P. Lingvall

IGC Proceedings (1977-2023)

An increasing use of whole-crop cereals, as supplementary feed, has increased interest in development of efficient ways of preserving these forages to achieve a high hygienic quality. It is known that ensiling of whole-cereals often results in silages with high concentrations of butyric acid (Weissbach & Haacker, 1988). Furthermore, problems with poor aerobic stability still persist despite the use of lactic acid bacteria (Filya et al., 2000). Therefore, the objective of this study was to examine the effect of different types of additive mixtures on the fermentation process and aerobic stability of precision chopped and baled silages.


Medical School Watercooler Newsletter - February 17, 2023, Lindsey Lyle Feb 2023

Medical School Watercooler Newsletter - February 17, 2023, Lindsey Lyle

Watercooler Newsletter

This is the February 17, 2023 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

  • Inabnet to present Fazier / Leigh Memorial Lectures
  • Faculty development to focus on conflict resolution
  • Teaching kitchen provides hands-on culinary medicine experience for medical students
  • Menger invited to present at international symposium
  • Pierce presents talk on HPV, cervical cancer
  • Solidarity Bingo winners announced for solidarity week
  • Save the date: USA Neuroscience Symposium
  • Distinguished Scientists seminar set for Feb. 16
  • USA researchers uncover novel mechanism that supports survival of pancreatic cancel cells


Bill Everard: The 8 Year Undergrad And Ads In Student Media, University Libraries Feb 2023

Bill Everard: The 8 Year Undergrad And Ads In Student Media, University Libraries

East Campus Oral Histories

WMU Alum Bill Everard meets with Cassie Kotrch virtually over Zoom to discuss his 8 years as an undergrad at WMU and the memories and stories he has as a student in ROTC, College of Business, and Communications as well as working at Western Herald and WIDR selling ads.


The Bison, February 17, 2023 Feb 2023

The Bison, February 17, 2023

The Bison Newspapers

No abstract provided.


February 17, 2023 Ereporter, University Of Alabama At Birmingham Feb 2023

February 17, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Price Analysis Of Aquafeed Containing Microalgae (Dunaliella Salina (Dunal) Teodoresco 1905 Meal For Color Enhancement In Shrimp, Wa Iba, Sumarno, Ruslaini, Agus Kurnia, Irdam Riani Feb 2023

Price Analysis Of Aquafeed Containing Microalgae (Dunaliella Salina (Dunal) Teodoresco 1905 Meal For Color Enhancement In Shrimp, Wa Iba, Sumarno, Ruslaini, Agus Kurnia, Irdam Riani

Fisheries, Animal and Veterinary Sciences Faculty Publications

The price of aqua feed containing Dunaliella salina meal was calculated. Also, the formulated feed’s protein, lipid, and total carotenoid content were examined. The price of shrimp feed containing D. salina meal was higher than commercial feed with better protein and carotenoid content in the feed. This indicated that the inclusion of microalgae meal may increase coloration and growth in shrimp. We recommend using these formulated fish in shrimp aquaculture with necessary investment in microalgae meal and aqua feed production.


Transcriptome, Proteome, And Protein Synthesis Within The Intracellular Cytomatrix, Tattym E Shaiken, Sandra L Grimm, Mohamad Siam, Amanda Williams, Abdol-Hossein Rezaeian, Daniel Kraushaar, Emily Ricco, Matthew J Robertson, Cristian Coarfa, Antrix Jain, Anna Malovannaya, Fabio Stossi, Antone R Opekun, Alyssa P Price, Julien Dubrulle Feb 2023

Transcriptome, Proteome, And Protein Synthesis Within The Intracellular Cytomatrix, Tattym E Shaiken, Sandra L Grimm, Mohamad Siam, Amanda Williams, Abdol-Hossein Rezaeian, Daniel Kraushaar, Emily Ricco, Matthew J Robertson, Cristian Coarfa, Antrix Jain, Anna Malovannaya, Fabio Stossi, Antone R Opekun, Alyssa P Price, Julien Dubrulle

Faculty, Staff and Students Publications

Despite the knowledge that protein translation and various metabolic reactions that create and sustain cellular life occur in the cytoplasm, the structural organization within the cytoplasm remains unclear. Recent models indicate that cytoplasm contains viscous fluid and elastic solid phases. We separated these viscous fluid and solid elastic compartments, which we call the cytosol and cytomatrix, respectively. The distinctive composition of the cytomatrix included structural proteins, ribosomes, and metabolome enzymes. High-throughput analysis revealed unique biosynthetic pathways within the cytomatrix. Enrichment of biosynthetic pathways in the cytomatrix indicated the presence of immobilized biocatalysis. Enzymatic immobilization and segregation can surmount spatial impediments, …


An Innovative Approach To Improve Oil Production And Quality Of Mustard (Brassica Juncea L.) With Multi-Nutrient-Rich Polyhalite, Biswajit Pramanick, B.S. Mahapatra, Debarati Datta, Prithwiraj Dey, S.P. Singh, Ajay Kumar, Bappa Paramanik, Neeraj Awasthi Feb 2023

An Innovative Approach To Improve Oil Production And Quality Of Mustard (Brassica Juncea L.) With Multi-Nutrient-Rich Polyhalite, Biswajit Pramanick, B.S. Mahapatra, Debarati Datta, Prithwiraj Dey, S.P. Singh, Ajay Kumar, Bappa Paramanik, Neeraj Awasthi

Department of Agronomy and Horticulture: Faculty Publications

Polyhalite popularly known as POLY4 is a multi-nutrient fertiliser containing K, S, Mg, Ca, and micronutrients. POLY4 has a low carbon footprint, is certified for organic agriculture, and has the potential to improve crop productivity and quality attributes Indian mustard which often faces challenges due to imbalanced nutrition supplied in the current fertilisation schedule. The hypothesis of the study was that the multi-nutrient fartiliser POLY4 can ensure balanced nutrition for Indian mustard. Considering this, a field experiment was conducted during the winter seasons of 2017–18 and 2018–19 to evaluate the effect of POLY4 on Indian mustard (Brassica juncea L.) …


Tracking The Evolution Of Esophageal Squamous Cell Carcinoma Under Dynamic Immune Selection By Multi-Omics Sequencing, Sijia Cui, Nicholas Mcgranahan, Jing Gao, Peng Chen, Wei Jiang, Lingrong Yang, Li Ma, Junfang Liao, Tian Xie, Congying Xie, Tariq Enver, Shixiu Wu Feb 2023

Tracking The Evolution Of Esophageal Squamous Cell Carcinoma Under Dynamic Immune Selection By Multi-Omics Sequencing, Sijia Cui, Nicholas Mcgranahan, Jing Gao, Peng Chen, Wei Jiang, Lingrong Yang, Li Ma, Junfang Liao, Tian Xie, Congying Xie, Tariq Enver, Shixiu Wu

Children’s Nutrition Research Center Staff Publications

Intratumoral heterogeneity (ITH) has been linked to decreased efficacy of clinical treatments. However, although genomic ITH has been characterized in genetic, transcriptomic and epigenetic alterations are hallmarks of esophageal squamous cell carcinoma (ESCC), the extent to which these are heterogeneous in ESCC has not been explored in a unified framework. Further, the extent to which tumor-infiltrated T lymphocytes are directed against cancer cells, but how the immune infiltration acts as a selective force to shape the clonal evolution of ESCC is unclear. In this study, we perform multi-omic sequencing on 186 samples from 36 primary ESCC patients. Through multi-omics analyses, …


Alternative Polyadenylation Alters Protein Dosage By Switching Between Intronic And 3’Utr Sites, Nicola De Prisco, Caitlin Ford, Nathan D Elrod, Winston Lee, Lauren C Tang, Kai-Lieh Huang, Ai Lin, Ping Ji, Venkata S Jonnakuti, Lia Boyle, Maximilian Cabaj, Salvatore Botta, Katrin Õunap, Karit Reinson, Monica H Wojcik, Jill A Rosenfeld, Weimin Bi, Kristian Tveten, Trine Prescott, Thorsten Gerstner, Audrey Schroeder, Chin-To Fong, Jaya K George-Abraham, Catherine A Buchanan, Andrea Hanson-Khan, Jonathan A Bernstein, Aikaterini A Nella, Wendy K Chung, Vicky Brandt, Marko Jovanovic, Kimara L Targoff, Hari Krishna Yalamanchili, Eric J Wagner, Vincenzo A Gennarino Feb 2023

Alternative Polyadenylation Alters Protein Dosage By Switching Between Intronic And 3’Utr Sites, Nicola De Prisco, Caitlin Ford, Nathan D Elrod, Winston Lee, Lauren C Tang, Kai-Lieh Huang, Ai Lin, Ping Ji, Venkata S Jonnakuti, Lia Boyle, Maximilian Cabaj, Salvatore Botta, Katrin Õunap, Karit Reinson, Monica H Wojcik, Jill A Rosenfeld, Weimin Bi, Kristian Tveten, Trine Prescott, Thorsten Gerstner, Audrey Schroeder, Chin-To Fong, Jaya K George-Abraham, Catherine A Buchanan, Andrea Hanson-Khan, Jonathan A Bernstein, Aikaterini A Nella, Wendy K Chung, Vicky Brandt, Marko Jovanovic, Kimara L Targoff, Hari Krishna Yalamanchili, Eric J Wagner, Vincenzo A Gennarino

Faculty, Staff and Students Publications

Alternative polyadenylation (APA) creates distinct transcripts from the same gene by cleaving the pre-mRNA at poly(A) sites that can lie within the 3' untranslated region (3'UTR), introns, or exons. Most studies focus on APA within the 3'UTR; however, here, we show that CPSF6 insufficiency alters protein levels and causes a developmental syndrome by deregulating APA throughout the transcript. In neonatal humans and zebrafish larvae, CPSF6 insufficiency shifts poly(A) site usage between the 3'UTR and internal sites in a pathway-specific manner. Genes associated with neuronal function undergo mostly intronic APA, reducing their expression, while genes associated with heart and skeletal function …


The Effects Of Carbohydrate Intake On Body Composition And Muscular Strength In Trained Men Undergoing A Progressive Resistance Training, Alex Silva Ribeiro, Kamila Quintilhano, Witalo Kassiano, João Pedro Nunes, Ademar Avelar, Michele C. Trindade, Andreo Aguiar, Brad Schoenfeld, Edilson Serpeloni Cyrino Feb 2023

The Effects Of Carbohydrate Intake On Body Composition And Muscular Strength In Trained Men Undergoing A Progressive Resistance Training, Alex Silva Ribeiro, Kamila Quintilhano, Witalo Kassiano, João Pedro Nunes, Ademar Avelar, Michele C. Trindade, Andreo Aguiar, Brad Schoenfeld, Edilson Serpeloni Cyrino

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 267-280, 2023. This study's purpose was to compare the effects of different carbohydrate (CHO) intakes on body composition and muscular strength following eight weeks of resistance training (RT) in pre-conditioned men. In addition, we explored the individual responses to different CHO intakes. Twenty-nine young men volunteered to participate in this study. The participants were divided into two groups according to their relative CHO intake: lower (L-CHO; n = 14) and higher (H-CHO; n = 15). Participants performed a RT program four days a week for eight weeks. The lean soft tissue (LST) and fat …


Astaxanthin Reduces Heart Rate And Carbohydrate Oxidation Rates During Exercise In Overweight Individuals, Alissa Wika, Kyle W. Reason, Matt Green, Lauren Killen, Matthew J. Mcallister, Hunter Waldman Feb 2023

Astaxanthin Reduces Heart Rate And Carbohydrate Oxidation Rates During Exercise In Overweight Individuals, Alissa Wika, Kyle W. Reason, Matt Green, Lauren Killen, Matthew J. Mcallister, Hunter Waldman

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 252-266, 2023. Astaxanthin (AX) is an antioxidant which may spare endogenous carbohydrates and improve fat oxidation rates, thus improving metabolic flexibility. To date, no studies have attempted to examine the impact of AX in an overweight cohort, whom often suffer from metabolic inflexibility. Nineteen subjects (mean ± SD: age: 27.5 ± 6.3 years; height: 169.7 ± 9.0 cm; body mass: 96.4 ± 17.9 kg; BF%: 37.9 ± 7.0%; BMI: 33.4 ± 5.6 kg/m2; VO2peak: 25.9 ± 6.7 ml·kg−1·min−1) were recruited and supplemented with either 12 mg …


Effects Of Varying Dietary Ratios Of Lucerne To Maize Silage On Production And Microbial Protein Synthesis In Lactating Dairy Cows, G. A. Broderick, A. F. Brito Feb 2023

Effects Of Varying Dietary Ratios Of Lucerne To Maize Silage On Production And Microbial Protein Synthesis In Lactating Dairy Cows, G. A. Broderick, A. F. Brito

IGC Proceedings (1977-2023)

Lucerne silage (LS) is high in total CP and rumen degraded protein (RDP) but low in fermentable energy, while maize silage (MS) is a good source of fermentable energy but low in RDP. Thus, these silages are complementary and feeding them at optimum ratio should increase nutrient efficiency in lactating cows. Dhiman & Satter (1997) observed greater milk yield when the dietary forage was 2/3 LS and 1/3 MS. The objective of this experiment was to optimise the dietary LS:MS ratio for production, microbial protein and N utilisation.


Effect Of Stage Of Maturity On The Nutrient Content Of Alfalfa, Y. Tyrolova, A. Vyborna Feb 2023

Effect Of Stage Of Maturity On The Nutrient Content Of Alfalfa, Y. Tyrolova, A. Vyborna

IGC Proceedings (1977-2023)

Alfalfa (Medicago sativa), one of the major agricultural crops in the Czech Republic, is grown on 15.8% of the arable land. Alfalfa silage forms a substantial part of diets for farm animals. It is very important to choose a suitable term of harvesting for ensilage from the view of optimal nutrient content. The stage of maturity at cutting has large effects on each component, except crude protein (Yu et al., 2004). Alfalfa can be difficult to ensile due to a high buffering capacity and a low WSC content.


Assessing The Impacts Of Global Warming On Mangrove Plants Growth In Malaysia, Baseem Tamimi, Wan Juliana Wan Ahmad, Mohd Nizam Mohd Said, Che Radziah Che Mohd Zain Feb 2023

Assessing The Impacts Of Global Warming On Mangrove Plants Growth In Malaysia, Baseem Tamimi, Wan Juliana Wan Ahmad, Mohd Nizam Mohd Said, Che Radziah Che Mohd Zain

Al-Bahir

Climate change issues have sparked intense debate around the world in recent years. Malaysia faces critical issues with global warming, which has changed the local climate, threatening critical ecosystems, including mangrove forests, and creating challenges in their habitat. This study was conducted to investigate the morphological and physiological attributes of the mangrove Rhizophora apiculata in response to air temperature for the selection of tree species that can adapt to climate change. The seedlings were grown in controlled growth chambers with temperatures, of 21,28, and 38°C, under elevated CO2 at 650 ppm for three months. The plants were watered with three …


Issue 412: February 16-March 2, 2023, The Local Voice Feb 2023

Issue 412: February 16-March 2, 2023, The Local Voice

The Local Voice

No abstract provided.


The Minutes Of The Marshall University Staff Council Meeting, February 2023, Marshall University Staff Council Feb 2023

The Minutes Of The Marshall University Staff Council Meeting, February 2023, Marshall University Staff Council

Staff Council Minutes

No abstract provided.


Journal Of Dairy Science® 2022 Editorial Report, Paul J. Kononoff Feb 2023

Journal Of Dairy Science® 2022 Editorial Report, Paul J. Kononoff

Department of Animal Science: Faculty Publications

In 2022, the 105th volume of the Journal of Dairy Science was published. As we review the journal’s last year, it may be useful to reflect on the purpose of scientific publishing. This can be simply stated as the dissemination of results that extends knowledge to open the door for new concepts or advances in the field (Chan, 2018). Similar to other journals, in addition to original research articles, Journal of Dairy Science also publishes invited reviews and other paper types to pursue this purpose. The journal also has other valuable roles. For example, scientific journals actively support authors in …


February 16, 2023, Caa Feb 2023

February 16, 2023, Caa

Minutes

No abstract provided.


Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman Feb 2023

Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman

Publications and Research

Background: Turkish immigrants form the largest ethnic minority group in the

Netherlands and show a higher prevalence of (i) cardiovascular disease (CVD),

(ii) cigarette smoking, and (iii) type 2 diabetes (T2D) as compared to the native

Dutch. This study examines the association of CVD risk factors: serum cotinine, as

an indicator of cigarette smoke, and lipid-related indices among first-generation

(foreign-born) Turkish immigrants with T2D living in deprived neighbourhoods in the

Netherlands.

Methods: A total of 110 participants, physician-diagnosed with T2D, aged 30 years

and older, were recruited by convenience sampling from the Schilderswijk

neighbourhood of The Hague in a clinic-based …


Factors Associated With Response To Growth Hormone In Pediatric Growth Disorders: Results Of A 5-Year Registry Analysis, Judith L. Ross, Moshe Fridman, Nicky Kelepouris, Kristine Murray, Nils Krone, Michel Polak, Tilman R Rohrer, Alberto Pietropoli, Neil Lawrence, Philippe Backeljauw Feb 2023

Factors Associated With Response To Growth Hormone In Pediatric Growth Disorders: Results Of A 5-Year Registry Analysis, Judith L. Ross, Moshe Fridman, Nicky Kelepouris, Kristine Murray, Nils Krone, Michel Polak, Tilman R Rohrer, Alberto Pietropoli, Neil Lawrence, Philippe Backeljauw

Department of Pediatrics Faculty Papers

Context: Growth hormone (GH) therapy can increase linear growth in patients with growth hormone deficiency (GHD), Turner syndrome (TS), Noonan syndrome (NS), and Prader-Willi syndrome (PWS), although outcomes vary by disease state.

Objective: To assess growth and identify factors associated with growth response with long-term GH therapy.

Methods: Data from pediatric patients with GHD, TS, NS, and PWS obtained at GH treatment initiation (baseline) and annually for 5 years in the ANSWER Program and NordiNet® IOS were analyzed retrospectively. Height standard deviation score (HSDS) was assessed over time, and multivariate analyses determined variables with significant positive effects on growth outcomes …


Quitting Smoking After A Cancer Diagnosis Is Associated With High-Risk Neutrophil-To-Lymphocyte Ratio Among Tobacco Use-Related Cancer Survivors, You Lu, Katherine Kwong, James Wells, Andrea Edwards, Zhong Chen, Tung-Sung Tseng, Kun Zhang Feb 2023

Quitting Smoking After A Cancer Diagnosis Is Associated With High-Risk Neutrophil-To-Lymphocyte Ratio Among Tobacco Use-Related Cancer Survivors, You Lu, Katherine Kwong, James Wells, Andrea Edwards, Zhong Chen, Tung-Sung Tseng, Kun Zhang

School of Public Health Faculty Publications

Quitting smoking could potentially minimize the risk of a high neutrophil-to-lymphocyte ratio (NLR) among tobacco use-related (TUR) cancer survivors. A total of 1263 TUR cancer survivors aged 20 to 85 years old were investigated using data from the National Health and Nutritional Examination Survey 1999-2018. The primary outcome was the NLR, which was defined as having two levels: high-risk (≥ 3) and low-risk (< 3). The association between smoking cessation time and a high-risk NLR level was analyzed using weighted logistic regression models. Overall, the current smoking rate of TUR cancer survivors was found to be 21.7%. Older age (75 years above), gender and respiratory-related cancers are covariables associated with high risk of NLR levels for individual who identified as Non-Hispanic White (NHW). Non-Hispanic Black (NHB) (n = 27) who quit smoking after a cancer diagnosis were associated with the highest risk of a high NLR (OR 4.83, 95% CI 1.40-16.61, p = 0.01) compared to NHB nonsmokers (n = 139). These findings suggest that the risk of a high NLR level is strongly associated with the time of smoking cessation in NHB TUR cancer survivors. As a result, NHB TUR cancer survivors should quit smoking as soon as possible because the benefits of quitting smoking were observed over the 5 year period following smoking cessation.