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2023

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Poverty And Poverty Alleviation Policies In The North Central Zone Of Nigeria, Gloria Ese Olotu Dr Mar 2023

Poverty And Poverty Alleviation Policies In The North Central Zone Of Nigeria, Gloria Ese Olotu Dr

Bullion

The paper examined poverty situation in the north central and the poverty alleviation policies of government as they affect the people of the north central zone in particular and Nigeria generally. This study was carried out in the face of the fact that poverty has characterized the Nigerian society such that over 70% of her citizens live below poverty line predicated by hunger, unemployment, poor housing, poor health care and other deprivations in spite of numerous government policies and programs aimed at alleviating or eradicating poverty in Nigeria since independence. Data for the study were generated through both the primary …


Chronic Environmental Circadian Disruption Increases Atherosclerosis And Dyslipidemia In Female, But Not Male, Apolipoproteine-Deficient Mice, Jeffrey M. Chalfant, Deborah A. Howatt, Victoria B. Johnson, Lisa R. Tannock, Alan Daugherty, Julie S. Pendergast Mar 2023

Chronic Environmental Circadian Disruption Increases Atherosclerosis And Dyslipidemia In Female, But Not Male, Apolipoproteine-Deficient Mice, Jeffrey M. Chalfant, Deborah A. Howatt, Victoria B. Johnson, Lisa R. Tannock, Alan Daugherty, Julie S. Pendergast

Saha Cardiovascular Research Center Faculty Publications

Shift work chronically disrupts circadian rhythms and increases the risk of developing cardiovascular disease. However, the mechanisms linking shift work and cardiovascular disease are largely unknown. The goal of this study was to investigate the effects of chronically shifting the light-dark (LD) cycle, which models the disordered exposure to light that may occur during shift work, on atherosclerosis. Atherosclerosis is the progressive accumulation of lipid-filled lesions within the artery wall and is the leading cause of cardiovascular disease. We studied ApolipoproteinE-deficient (ApoE−/−) mice that are a well-established model of atherosclerosis. Male and female ApoE−/− mice were housed in control 12L:12D …


Social And Behavior Change And The Enabling Environment For Family Planning, Breakthrough Research Mar 2023

Social And Behavior Change And The Enabling Environment For Family Planning, Breakthrough Research

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.


Results Of The 2022 Immunization Status Survey Of 24-Month-Old Children In Tennessee, Tennessee. Department Of Health. Mar 2023

Results Of The 2022 Immunization Status Survey Of 24-Month-Old Children In Tennessee, Tennessee. Department Of Health.

Immunization Rates

No abstract provided.


Intensifying A Crop–Fallow System: Impacts On Soil Properties, Crop Yields, And Economics, S. J. Ruis, S. Stepanovic, Humberto Blanco-Canqui Mar 2023

Intensifying A Crop–Fallow System: Impacts On Soil Properties, Crop Yields, And Economics, S. J. Ruis, S. Stepanovic, Humberto Blanco-Canqui

Department of Agronomy and Horticulture: Faculty Publications

Intensifying crop–fallow systems could address increased weed control costs, increased land or rental costs, reduced crop diversity, and degraded soil properties in water-limited environments. One strategy to intensify such systems could be the insertion of a short-season crop during fallow. But, how this strategy affects soils, crop production, and farm economics needs further research. Thus, we studied the impacts of replacing fallow in a winter wheat (Triticum aestivum L)–corn (Zea mays L.)–fallow system with a short-season spring crop [field pea (Pisum sativum L.)] on crop yields and economics from 2015 to 2019 and 5-yr cumulative effects on …


Cftc & Sec: The Wild West Of Cryptocurrency Regulation, Taylor Anne Moffett Mar 2023

Cftc & Sec: The Wild West Of Cryptocurrency Regulation, Taylor Anne Moffett

University of Richmond Law Review

Over the past few years, a turf war has been brewing between the Commodity Futures Trading Commission (“CFTC”) and the Securities and Exchange Commission (“SEC”) over which agency should regulate cryptocurrencies. Both agencies have pursued numerous enforcement actions over the cryptocurrencies they believe to be within their jurisdiction. This turf war has many moving components, but the focus always comes back to one question: which cryptocurrencies are commodities, and which cryptocurrencies are securities? The distinction is important because the CFTC has statutory authority to regulate commodities, whereas the SEC has statutory authority to regulate securities. This Comment rejects the pursuit …


The Role Of The Novel Diguanylate Cyclase Pg_0686 In Oxidative Stress Resistance In Porphyromonas Gingivalis W83, Alexia Danielle Ximinies Mar 2023

The Role Of The Novel Diguanylate Cyclase Pg_0686 In Oxidative Stress Resistance In Porphyromonas Gingivalis W83, Alexia Danielle Ximinies

Loma Linda University Electronic Theses, Dissertations & Projects

The survival/ adaptation of Porphyromonas gingivalis to the inflammatory environment of the periodontal pocket requires an ability to overcome oxidative stress. Several functional classes of genes, depending on the severity and duration of the exposure, were induced in P. gingivalis under H2O2-induced oxidative stress, including the PG0686 gene which was upregulated ca. 10-fold. In addition, its upregulation was also observed in the presence of oxygen and nitric oxide. This study is aimed to further characterize the function of this gene in response to H2O2. PG_0686, annotated as a hypothetical protein of unknown function, is a 60 kDa protein with a …


Aged 539 Graduate Internship Report - Pacheco High School, Spencer C. Bronken Mar 2023

Aged 539 Graduate Internship Report - Pacheco High School, Spencer C. Bronken

Agricultural Education: Graduate Internship Reports

This internship and project report includes validation documents required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The supporting material includes information to receive state and local funding, outline the goals and objectives of the program, along with an overview of Pacheco High School, the agriculture program, and the community.


Covid-19 In Bangladesh: A Systematic Review Of The Literature From March 2020 To March 2021, Md. Shahin Parvez, Md. Al-Mamun, Md. Anisur Rahaman, Sheuli Akter, Kaniz Fatema, Halimatus Sadia, Anika Intesar Mar 2023

Covid-19 In Bangladesh: A Systematic Review Of The Literature From March 2020 To March 2021, Md. Shahin Parvez, Md. Al-Mamun, Md. Anisur Rahaman, Sheuli Akter, Kaniz Fatema, Halimatus Sadia, Anika Intesar

Journal of Global Business Insights

COVID-19 has undoubtedly absorbed the global public's angst. It has quickly disturbed global life and will have long-term and short-term consequences on several sectors. This comprehensive review study's goal is to discover what research has been done in a year since the beginning of coronavirus in Bangladesh. Consequently, the current study examined the pervasiveness and affiliation of social and economic issues, health and psychological issues and individual perceptions, key challenges, strategies and policy systems, public health, online education, agriculture and food security, criminal activities related to outbreaks, Rohingya refugee issues, and the quality of domestic violence behaviors. The review used …


A Genealogy Of Open, Betsy Yoon Mar 2023

A Genealogy Of Open, Betsy Yoon

Publications and Research

The term open has become a familiar part of library and education practice and discourse, with open source software being a common referent. However, the conditions surrounding the emergence of the open source movement are not well understood within librarianship. After identifying capitalism and neoliberalism as structures that shape library and open practice, this article contextualizes the term open by delineating the discursive struggle within the free software movement that led to the emergence of the open source movement. An understanding of the genealogy of open can lend clarity to many of the contradictions that have been grappled with in …


Evaluating The Relationship Between Circadian Rhythms And Sleep, Metabolic And Cardiovascular Disorders: Current Clinical Evidence In Human Studies, Maria Mentzelou, Sousana K. Papadopoulou, Dimitrios Papandreou, Maria Spanoudaki, Antonios Dakanalis, Georgios K. Vasios, Gavriela Voulgaridou, Eleni Pavlidou, Maria Mantzorou, Constantinos Giaginis Mar 2023

Evaluating The Relationship Between Circadian Rhythms And Sleep, Metabolic And Cardiovascular Disorders: Current Clinical Evidence In Human Studies, Maria Mentzelou, Sousana K. Papadopoulou, Dimitrios Papandreou, Maria Spanoudaki, Antonios Dakanalis, Georgios K. Vasios, Gavriela Voulgaridou, Eleni Pavlidou, Maria Mantzorou, Constantinos Giaginis

All Works

Circadian rhythms are generated by the circadian clock, a self-sustained internal timing system that exhibits 24-h rhythms in the body. Many metabolic, cellular, behavioral and physiological processes are regulated by the circadian clock in coordination with environmental cues. The present study is a comprehensive review of the currently existing evidence concerning the relationship between circadian rhythms and sleep, metabolic, and cardiovascular disorders. We thoroughly searched the online databases PubMed, Scopus, and Web of Science to find the existing clinical studies from the last twenty-three years (2000–2023). Circadian misalignment was found to be associated with an increase in the risk of …


“It Helped Us More Than I Could Have Imagined”: How The 2021 Expanded Child Tax Credit Supported Families Raising Children With Disabilities, Laura Brugger, Stephen Roll, Leah Hamilton, Allyson Baughman, Meg Comeau, Candace Jarzombeck, Caroline Parker Mar 2023

“It Helped Us More Than I Could Have Imagined”: How The 2021 Expanded Child Tax Credit Supported Families Raising Children With Disabilities, Laura Brugger, Stephen Roll, Leah Hamilton, Allyson Baughman, Meg Comeau, Candace Jarzombeck, Caroline Parker

Social Policy Institute Research

The 2021 expanded Child Tax Credit (CTC) provided temporary enhancements to the existing CTC for the tax years 2021 and 2022. Under the expanded credit, families with children under the age of 18 were eligible to receive a credit of up to $3,000 per child ($3,600 for children under the age of 6). In addition, half the credit was paid out on a monthly basis rather than as a one-time payment at tax time. This provision was designed to provide more immediate financial support to families with children during the COVID-19 pandemic. However, it also supported families who were at …


Changement Social Et Comportemental Et Environnement Favorable À La Planification Familiale, Breakthrough Research Mar 2023

Changement Social Et Comportemental Et Environnement Favorable À La Planification Familiale, Breakthrough Research

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.


Digital Asset Regulation: Peering Into The Past, Peering Into The Future, Kevin Werbach Mar 2023

Digital Asset Regulation: Peering Into The Past, Peering Into The Future, Kevin Werbach

William & Mary Law Review

Blockchain is often compared to the internet as a disruptive technology that will realign economic structures across the world. This analogy extends to law and regulation. Similar to internet-based services, digital assets raise a host of challenges for policymakers. They also pose general questions regarding the desirability and practicality of regulating decentralized systems. Such debates play out against a backdrop of concerns that regulatory action will chill innovation or push market activity to more tolerant jurisdictions. The story of internet policy in the late 1990s and early 2000s therefore provides important lessons for policymakers today when confronting digital assets. Two …


Fables Of Scarcity In Ip, Zahr K. Said Mar 2023

Fables Of Scarcity In Ip, Zahr K. Said

Articles

In this chapter, I use methods drawn from literary analysis to bear on artificial scarcity and explore how literary and legal storytelling engages in scarcity mongering. I find three particular narrative strategies calculated to compel a conclusion in favor of propertization: the spectacle of need, the diversionary tactic, and the rallying cry. First, I unpack the spectacle of need and its diversionary aspects through several literary accounts of scarcity and starvation. I juxtapose Franz Kafka's “A Hunger Artist,” a story explicitly centered on a wasting body, with J.M. Coetzee's The Life and Times of Michael K. Second, to explore how …


Egr1 Drives Cell Proliferation By Directly Stimulating Tfeb Transcription In Response To Starvation, Marcella Cesana, Gennaro Tufano, Francesco Panariello, Nicolina Zampelli, Susanna Ambrosio, Rossella De Cegli, Margherita Mutarelli, Lorenzo Vaccaro, Micheal J Ziller, Davide Cacchiarelli, Diego L Medina, Andrea Ballabio Mar 2023

Egr1 Drives Cell Proliferation By Directly Stimulating Tfeb Transcription In Response To Starvation, Marcella Cesana, Gennaro Tufano, Francesco Panariello, Nicolina Zampelli, Susanna Ambrosio, Rossella De Cegli, Margherita Mutarelli, Lorenzo Vaccaro, Micheal J Ziller, Davide Cacchiarelli, Diego L Medina, Andrea Ballabio

Duncan NRI Faculty and Staff Publications

The stress-responsive transcription factor EB (TFEB) is a master controller of lysosomal biogenesis and autophagy and plays a major role in several cancer-associated diseases. TFEB is regulated at the posttranslational level by the nutrient-sensitive kinase complex mTORC1. However, little is known about the regulation of TFEB transcription. Here, through integrative genomic approaches, we identify the immediate-early gene EGR1 as a positive transcriptional regulator of TFEB expression in human cells and demonstrate that, in the absence of EGR1, TFEB-mediated transcriptional response to starvation is impaired. Remarkably, both genetic and pharmacological inhibition of EGR1, using the MEK1/2 inhibitor Trametinib, significantly reduced the …


Prevalence Of Iron Deficiency In Patients With Inherited Bleeding Disorders, Thomas Cochran, Brian Lee, Shannon Carpenter Mar 2023

Prevalence Of Iron Deficiency In Patients With Inherited Bleeding Disorders, Thomas Cochran, Brian Lee, Shannon Carpenter

Posters

Background: Synthesis of hemoglobin is one of several important roles iron plays in the human body. Approximately 50% of all anemia cases may be caused by iron deficiency which is frequently caused by chronic blood loss. Patients with bleeding disorders have greater propensity for blood loss and therefore may have a higher prevalence of iron deficiency when compared to the general population. However, few studies have assessed the prevalence of iron deficiency in children with inherited bleeding disorders. Objectives: This study aims to identify the prevalence of iron deficiency in children with an inherited bleeding disorder. Methods: A retrospective analysis …


Utilizing The Rpe‑Clamp Model To Examine Interactions Among Factors Associated With Perceived Fatigability And Performance Fatigability In Women And Men, Robert W. Smith, Terry J. Housh, Jocelyn E. Arnett, John Paul V. Anders, Tyler J. Neltner, Dolores G. Ortega, Richard J. Schmidt, Glen O. Johnson Mar 2023

Utilizing The Rpe‑Clamp Model To Examine Interactions Among Factors Associated With Perceived Fatigability And Performance Fatigability In Women And Men, Robert W. Smith, Terry J. Housh, Jocelyn E. Arnett, John Paul V. Anders, Tyler J. Neltner, Dolores G. Ortega, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Purpose The purpose of the present study was to examine the interactions between perceived fatigability and performance fatigability in women and men by utilizing the RPE-Clamp model to assess the fatigue-induced effects of a sustained, isometric forearm flexion task anchored to RPE = 8 on time to task failure (TTF), torque, and neuromuscular responses.

Methods Twenty adults (10 men and 10 women) performed two, 3 s forearm flexion maximal voluntary isometric contractions (MVICs) followed by a sustained, isometric forearm flexion task anchored to RPE = 8 using the OMNI-RES (0–10) scale at an elbow joint angle of 100°. Electromyographic amplitude …


Exploring Diversity And Depth Of Knowledge, Metacognition, And Individual Ambidexterity, Deddi Tedjakumara Mar 2023

Exploring Diversity And Depth Of Knowledge, Metacognition, And Individual Ambidexterity, Deddi Tedjakumara

Dissertations and Theses Collection (Open Access)

Recent data show that the average lifespan of a company listed in the Standard and Poor's 500 (S&P 500) Index has declined from 32 years in 1965 to 21 years in 2020 (Clark, 2021), and it is estimated that 75% of the companies listed in the S&P 500 today will disappear from the list by 2027 (Hillenbrand, 2019). Organizational theory holds that for a company to be sustainable, it must strike a balance between exploring new possibilities and exploiting old certainties (March, 1991). The ability to manage the tension between exploration and exploitation is important at both organizational and individual …


Detection Of Microbial Growth In Aseptic Food Products Using Non-Invasive Tunable Diode Laser Absorption Spectroscopy (Tdlas), Peter Myintzaw, Nicholas Brian Johnson, Máire Begley, Michael J. Callanan Mar 2023

Detection Of Microbial Growth In Aseptic Food Products Using Non-Invasive Tunable Diode Laser Absorption Spectroscopy (Tdlas), Peter Myintzaw, Nicholas Brian Johnson, Máire Begley, Michael J. Callanan

Department of Biological Sciences Publications

The sensitivity and reliability of Tunable Diode Laser Absorption Spectroscopy (TDLAS) for monitoring the growth of microorganisms in real food matrices was explored. The rapid and non-destructive TDLAS equipment uses laser light to monitor carbon dioxide changes due to microbial growth in the container head space which has the additional advantage of detecting contamination in products and packaging where visual inspection is not possible. TDLAS growth detection of Bacillus fengqiuensis, Candida albicans, Lactococcus lactis, Microbacterium luteolum, Paenibacillus chitinolyticus and Staphylococcus pasteuri was studied in various Ready To Feed (RTF) infant formula products. Detection of growth was correlated with cell numbers …


Development And Piloting Of A Novel Evaluation Tool For Childhood Obesity Prevention Programs, Heather Norman-Burgdolf, Anne R. Lindsay, Kelly Webber, Julie C. Parker, Ingrid K. Richards Adams, Rafida Idris, Laura Hubbs-Tait, Karen Chapman-Novakofski Mar 2023

Development And Piloting Of A Novel Evaluation Tool For Childhood Obesity Prevention Programs, Heather Norman-Burgdolf, Anne R. Lindsay, Kelly Webber, Julie C. Parker, Ingrid K. Richards Adams, Rafida Idris, Laura Hubbs-Tait, Karen Chapman-Novakofski

Journal of Human Sciences and Extension

Childhood obesity remains chronic and high in the U.S., driven by factors including poor dietary habits and lack of physical activity. Interventions that address multiple causal factors may be the most appropriate strategy to address rising childhood obesity rates. The Cooperative Extension Service offers programs across the country to address causal factors of childhood obesity, but few coordinated or concerted efforts have been made to determine overlap, reduce duplication, or identify best practices in programming. To fill this gap, the National Institute of Food and Agriculture Multistate Project W3005 Extension Workgroup sought to develop a novel tool to compare programs …


Implementing Inquiry Based Learning In Life Science Curriculum In Agricultural Education, Siera Meyer, Chance Kanode, Bryan Reiling, Nathan W. Conner, Christopher T. Stripling, Laura Young, Mathew Kreifels, Mark Balschweid Mar 2023

Implementing Inquiry Based Learning In Life Science Curriculum In Agricultural Education, Siera Meyer, Chance Kanode, Bryan Reiling, Nathan W. Conner, Christopher T. Stripling, Laura Young, Mathew Kreifels, Mark Balschweid

Journal of Human Sciences and Extension

As Agricultural Education shifts to a more science-based curriculum to help fulfill shortcomings of the current United States science test scores, teachers implementing Inquiry-Based Learning (IBL) is becoming more important. For Agriculture Educators to do this, training is necessary for both new and experienced educators. This study was conducted to gauge teacher attitudes toward and ability to integrate IBL in the classroom to meet these goals. Teacher knowledge was also assessed in four life science categories. Study results indicate that teachers have positive attitudes toward learning about IBL and implementing the model in the classrooms. Teachers also gained more content …


Aquaculture Extension Capacity In The Usda North-Central Region: Results From A Survey, J. Stuart Carlton, Amy M. Shambach, Kwamena Quagrainie Mar 2023

Aquaculture Extension Capacity In The Usda North-Central Region: Results From A Survey, J. Stuart Carlton, Amy M. Shambach, Kwamena Quagrainie

Journal of Human Sciences and Extension

We surveyed Agriculture and Natural Resources Extension staff across the USDA North-Central Region about aquaculture programming. Overall, 47%, 35%, and 15% of respondents indicated that stakeholders had contacted them about aquaponics, finfish aquaculture, and shrimp aquaculture, respectively. Approximately 8% of respondents indicated that they offered aquaculture or aquaponics programming; 45% and 55% indicated that they did not offer aquaculture and aquaponics programming, respectively, but were interested in offering it. These results indicate that there is interest in increasing Extension capacity in fish farming either by hiring new staff or through train-the-trainer models.


Validation Of The Entrainment Signal Regularity Index And Associations With Children’S Changes In Bmi, Jennette P Moreno, Kevin M Hannay, Amy R Goetz, Olivia Walch, Philip Cheng Mar 2023

Validation Of The Entrainment Signal Regularity Index And Associations With Children’S Changes In Bmi, Jennette P Moreno, Kevin M Hannay, Amy R Goetz, Olivia Walch, Philip Cheng

Children’s Nutrition Research Center Staff Publications

Objective: This study examined the validity of a novel metric of circadian health, the Entrainment Signal Regularity Index (ESRI), and its relationship to changes in BMI during the school year and summer.

Methods: In a longitudinal observational data set, this study examined the relationship between ESRI score and children's (n = 119, 5- to 8-year-olds) sleep and physical activity levels during the school year and summer, differences in ESRI score during the school year and summer, and the association of ESRI score during the school year and summer with changes in BMI across those time periods.

Results: The ESRI score …


In Utero Exposure To Antiemetic And Risk Of Adult-Onset Colorectal Cancer, Caitlin C Murphy, Piera M Cirillo, Nickilou Y Krigbaum, Amit G Singal, Barbara A Cohn Mar 2023

In Utero Exposure To Antiemetic And Risk Of Adult-Onset Colorectal Cancer, Caitlin C Murphy, Piera M Cirillo, Nickilou Y Krigbaum, Amit G Singal, Barbara A Cohn

Faculty, Staff and Student Publications

BACKGROUND: Incidence rates of colorectal cancer (CRC) are increasing among adults born in and after the 1960s, implicating pregnancy-related exposures introduced at that time as risk factors. Dicyclomine, an antispasmodic used to treat irritable bowel syndrome, was initially included in Bendectin (comprising doxylamine, pyridoxine, and dicyclomine), an antiemetic prescribed during pregnancy in the 1960s.

METHODS: We estimated the association between in utero exposure to Bendectin and risk of CRC in offspring of the Child Health and Development Studies, a multigenerational cohort that enrolled pregnant women in Oakland, CA, between 1959 and 1966 (n = 14 507 mothers and 18 751 …


Delphi Initiative For Early-Onset Colorectal Cancer (Direct) International Management Guidelines, Giulia Martina Cavestro, Alessandro Mannucci, Francesc Balaguer, Heather Hampel, Sonia S Kupfer, Alessandro Repici, Andrea Sartore-Bianchi, Toni T Seppälä, Vincenzo Valentini, Clement Richard Boland, Randall E Brand, Tineke E Buffart, Carol A Burke, Riccardo Caccialanza, Renato Cannizzaro, Stefano Cascinu, Andrea Cercek, Emma J Crosbie, Silvio Danese, Evelien Dekker, Maria Daca-Alvarez, Francesco Deni, Mev Dominguez-Valentin, Cathy Eng, Ajay Goel, Josè G Guillem, Britt B S L Houwen, Charles Kahi, Matthew F Kalady, Fay Kastrinos, Florian Kühn, Luigi Laghi, Andrew Latchford, David Liska, Patrick Lynch, Alberto Malesci, Gianluca Mauri, Elisa Meldolesi, Pål Møller, Kevin J Monahan, Gabriela Möslein, Caitlin C Murphy, Karlijn Nass, Kimmie Ng, Cristina Oliani, Enrico Papaleo, Swati G Patel, Marta Puzzono, Andrea Remo, Luigi Ricciardiello, Carla Ida Ripamonti, Salvatore Siena, Satish K Singh, Zsofia K Stadler, Peter P Stanich, Sapna Syngal, Stefano Turi, Emanuele Damiano Urso, Laura Valle, Valeria Stella Vanni, Eduardo Vilar, Marco Vitellaro, Yi-Qian Nancy You, Matthew B Yurgelun, Raffaella Alessia Zuppardo, Elena M Stoffel, Associazione Italiana Familiarità Ereditarietà Tumori, Collaborative Group Of The Americas On Inherited Gastrointestinal Cancer, European Hereditary Tumour Group, And The International Society For Gastrointestinal Hereditary Tumours Mar 2023

Delphi Initiative For Early-Onset Colorectal Cancer (Direct) International Management Guidelines, Giulia Martina Cavestro, Alessandro Mannucci, Francesc Balaguer, Heather Hampel, Sonia S Kupfer, Alessandro Repici, Andrea Sartore-Bianchi, Toni T Seppälä, Vincenzo Valentini, Clement Richard Boland, Randall E Brand, Tineke E Buffart, Carol A Burke, Riccardo Caccialanza, Renato Cannizzaro, Stefano Cascinu, Andrea Cercek, Emma J Crosbie, Silvio Danese, Evelien Dekker, Maria Daca-Alvarez, Francesco Deni, Mev Dominguez-Valentin, Cathy Eng, Ajay Goel, Josè G Guillem, Britt B S L Houwen, Charles Kahi, Matthew F Kalady, Fay Kastrinos, Florian Kühn, Luigi Laghi, Andrew Latchford, David Liska, Patrick Lynch, Alberto Malesci, Gianluca Mauri, Elisa Meldolesi, Pål Møller, Kevin J Monahan, Gabriela Möslein, Caitlin C Murphy, Karlijn Nass, Kimmie Ng, Cristina Oliani, Enrico Papaleo, Swati G Patel, Marta Puzzono, Andrea Remo, Luigi Ricciardiello, Carla Ida Ripamonti, Salvatore Siena, Satish K Singh, Zsofia K Stadler, Peter P Stanich, Sapna Syngal, Stefano Turi, Emanuele Damiano Urso, Laura Valle, Valeria Stella Vanni, Eduardo Vilar, Marco Vitellaro, Yi-Qian Nancy You, Matthew B Yurgelun, Raffaella Alessia Zuppardo, Elena M Stoffel, Associazione Italiana Familiarità Ereditarietà Tumori, Collaborative Group Of The Americas On Inherited Gastrointestinal Cancer, European Hereditary Tumour Group, And The International Society For Gastrointestinal Hereditary Tumours

Faculty, Staff and Student Publications

BACKGROUND & AIMS: Patients with early-onset colorectal cancer (eoCRC) are managed according to guidelines that are not age-specific. A multidisciplinary international group (DIRECt), composed of 69 experts, was convened to develop the first evidence-based consensus recommendations for eoCRC.

METHODS: After reviewing the published literature, a Delphi methodology was used to draft and respond to clinically relevant questions. Each statement underwent 3 rounds of voting and reached a consensus level of agreement of ≥80%.

RESULTS: The DIRECt group produced 31 statements in 7 areas of interest: diagnosis, risk factors, genetics, pathology-oncology, endoscopy, therapy, and supportive care. There was strong consensus that …


Metabolomic Markers Of Ultra-Processed Food And Incident Ckd, Donghan Su, Jingsha Chen, Shutong Du, Hyunju Kim, Bing Yu, Kari E Wong, Eric Boerwinkle, Casey M Rebholz Mar 2023

Metabolomic Markers Of Ultra-Processed Food And Incident Ckd, Donghan Su, Jingsha Chen, Shutong Du, Hyunju Kim, Bing Yu, Kari E Wong, Eric Boerwinkle, Casey M Rebholz

Faculty, Staff and Student Publications

BACKGROUND: High ultra-processed food consumption is associated with higher risk of CKD. However, there is no biomarker for ultra-processed food, and the mechanism through which ultra-processed food is associated with CKD is not clear. Metabolomics can provide objective biomarkers of ultra-processed food and provide important insights into the mechanisms by which ultra-processed food is associated with risk of incident CKD. Our objective was to identify serum metabolites associated with ultra-processed food consumption and investigate whether ultra-processed food-associated metabolites are prospectively associated with incident CKD.

METHODS: We used data from 3751 Black and White men and women (aged 45-64 years) in …


Prevalence, Genetic Characterization, And Antibiogram Of Salmonella Enterica Recovered From Buffalo Meat, Takwa Fathy, Amira Zakaria, Samir Abd-Elghany, Khalid Sallam Mar 2023

Prevalence, Genetic Characterization, And Antibiogram Of Salmonella Enterica Recovered From Buffalo Meat, Takwa Fathy, Amira Zakaria, Samir Abd-Elghany, Khalid Sallam

Mansoura Veterinary Medical Journal

Objective: This study aimed to determine the prevalence, virulence-associated genes and antimicrobial resistance of Salmonella species recovered from buffalo meat at Mansoura city in Egypt. Salmonella virulence genes were detected using polymerase chain reaction targeting invA, stn, and hilA genes.Design: Observational study.Samples: 120 samples.Procedures: A total of 120 buffalo meat samples were bacteriologically analyzed to isolate and characterize the Salmonella spp. and its virulence genes, in addition to their antimicrobial resistance.Results: Thirty (25%) out of 120-samples from buffalo meat were positive Salmonella spp. Out of the 191 phenotypically identified Salmonella isolates, only 58 strains were molecularly confirmed as Salmonella spp. …


Improving Interventions On Cardiovascular Disease And Diet: A Policy Incentive Analysis, Sandra Hurst Mar 2023

Improving Interventions On Cardiovascular Disease And Diet: A Policy Incentive Analysis, Sandra Hurst

Dissertations

Introduction: Various cardiovascular diseases (CVD) can be catastrophic and can lead to irreversible outcomes. There are limited, improved regulations on awareness of primordial and primary preventions that may decrease CVD progression and mortality. Before policies and recommendations can be set, policymakers should understand CVD and the importance of maintaining a healthy diet to decrease the risk of CVDs and improve patient adherence. Therefore, this project aims to analyze federal healthy food incentive policies to promote healthy diet behaviors that reduce CVD risk.

Method: The method used was existing data for a comparative policy analysis that included a policy proposal process: …


Innovations In Implant Therapy, Catherine Monchik, Isis Marsh Mar 2023

Innovations In Implant Therapy, Catherine Monchik, Isis Marsh

Publications and Research

No abstract provided.