Digital Commons Network^™

High Sucrose Consumption Decouples Intrinsic And Synaptic Excitability Of Agrp Neurons Without Altering Body Weight., Austin C Korgan, Klausen Oliveira-Abreu, Wei Wei, Sophie L A Martin, Zoey J D Bridges, José Henrique Leal-Cardoso, Catherine Kaczorowski, Kristen M S O'Connell

Faculty Research 2023

BACKGROUND/OBJECTIVE: As the obesity epidemic continues, the understanding of macronutrient influence on central nervous system function is critical for understanding diet-induced obesity and potential therapeutics, particularly in light of the increased sugar content in processed foods. Previous research showed mixed effects of sucrose feeding on body weight gain but has yet to reveal insight into the impact of sucrose on hypothalamic functioning. Here, we explore the impact of liquid sucrose feeding for 12 weeks on body weight, body composition, caloric intake, and hypothalamic AgRP neuronal function and synaptic plasticity.

METHODS: Patch-clamp electrophysiology of hypothalamic AgRP neurons, metabolic phenotyping and food …

Unreasonable Royalty: Realigning Economic Incentives Involving Innovation In The Age Of Patent Assertion Entities, Jordan Duenckel

The Business, Entrepreneurship & Tax Law Review

Patent litigation is a high-stakes endeavor when jury verdicts can be in the hundreds of millions or even billions. With this much at stake, the judicial system is ripe for abuse by parties that aren’t inventors or producers: nonpracticing entities. Various steps have been taken to mitigate or discourage the gaming of the system but have not been successful for various reasons. This Article proposes the novel solution of incorporating a federal damages cap into 35 U.S.C. § 284 to shift the underlying economic incentives toward innovation. After discussing some likely challenges to the proposal, this Article concludes that the …

2023-March-01-Primary Sources, University Marketing And Communication, East Tennessee State University

ETSU News

No abstract provided.

Cuyahoga County Grocery Store Assessment, 2023, Roger Sikes, B.J. Fletcher

All Maxine Goodman Levin School of Urban Affairs Publications

High profile grocery store closures in working class neighborhoods have galvanized community efforts and political will to address grocery store gaps – albeit in a reactive manner. Grocery stores are an essential part of our communities, providing access to food, medicine, jobs, household items and banking services. Their relevance merits a robust focus on policy solutions.

This Grocery Store Assessment is a collaboration among public sector entities and neighborhood leaders to better understand the grocery store landscape, learn from implementation efforts and develop proactive policy solutions. There are 223 small, mid and large-scale grocery stores and 11,000 grocery workers in …

A Case Of Acute Liver Failure Due To Artemisinin-Derived Herbal Supplements, Maria Jamil, Abdus Salam, Belinda Joseph Benher, Nour Nasiri, Ammad J. Chaudhary

Internal Medicine Articles

A 49-year-old female presented with malaise, nausea, vomiting, and discolored urine. She was found to have an acute liver failure with labs significant for aspartate aminotransferase (AST) of 2164, alanine aminotransferase (ALT) of 2425, alkaline phosphatase (ALP) of 106, total bilirubin of 3.6, and lactate dehydrogenase (LDH) of 2269. The international normalized ratio (INR) was also elevated at 1.9. All workup for acute liver failure was negative and it was found that she had started taking a new supplement called "Gut Health", which contained artemisinin, for weight loss and menopausal symptoms. After discontinuing the supplements and symptomatically treating her for …

Forage News [2023-03], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

No abstract provided.

Body Mass Index Percentiles Versus Body Composition Assessments: Challenges For Disease Risk Classifications In Children, Jody L. Clasey, Elizabeth Ann Easley, Margaret O'Bryan Murphy, Stefan G. Kiessling, Arnold Stromberg, Aric Schadler, Hong Huang, John A. Bauer

UK CARES Faculty Publications

Background: Identifying at-risk children with optimal specificity and sensitivity to allow for the appropriate intervention strategies to be implemented is crucial to improving the health and well-being of children. We determined relationships of body mass indexes for age and sex percentile (BMI%) classifications to actual body composition using validated and convenient methodologies and compared fat and non-fat mass estimates to normative cut-off reference values to determine guideline reliability. We hypothesized that we would achieve an improved ability to identify at-risk children using simple, non-invasive body composition and index measures.

Methods: Cross-sectional study of a volunteer convenience sample of 1,064 (537 …

Making Morbidity Multiple: History, Legacies, And Possibilities For Global Health, Justin Dixon, Emily Mendenhall, Edna Bosire, Felix Limbani, Rashida A. Ferrand, Clare I R. Chandler

Brain and Mind Institute

Multimorbidity has been framed as a pressing global health challenge that exposes the limits of systems organised around single diseases. This article seeks to expand and strengthen current thinking around multimorbidity by analysing its construction within the field of global health. We suggest that the significance of multimorbidity lies not only in challenging divisions between disease categories but also in what it reveals about the culture and history of transnational biomedicine. Drawing on social research from sub-Saharan Africa to ground our arguments, we begin by describing the historical processes through which morbidity was made divisible in biomedicine and how the …

Labor Market Regulation And Worker Power, Hiba Hafiz, Ioana Marinescu

University of Chicago Law Review

Due to a lack of competition among employers in the labor market, employers have monopsony power, or power to pay workers less than what the workers contribute to the employers’ bottom line. “Worker power” is workers’ ability to obtain higher wages and better working conditions. While the antitrust agencies have just begun developing policy and enforcement strategies to regulate employer monopsony, broader government policies that impact market forces, the formation of labor market institutions, and workers’ voices and exit options also play a defining role in shaping worker power relative to employers. For example, in addition to antitrust enforcement, worker …

Medical Device-Related Pressure Injury (Mdrpi) Prevention In The Intensive Care Unit (Icu): An Evidence Based Practice Quality Improvement Project, Sana Shah

DNP Projects

Introduction: All intensive care unit (ICU) patients utilize various medical devices for care and treatment, placing them at high-risk for medical device-related pressure injuries (MDRPIs), which can lead to life-threatening infections, wounds/scars, and consumption of additional time and products to rectify these issues. Lack of appropriate decompression measures and improper bedside handoff report was recognized in the ICU at a hospital in Connecticut (CT).

Method: A literature search using CINAHL, MEDLINE, and the Cochrane Database of Systematic Reviews was conducted, restricting the search to the period between 2018-2022. The keywords searched were: “pressure injuries,” “adult patients,” “intensive care …

Dredged Sediments Contain Potentially Beneficial Microorganisms For Agriculture And Little Harmful Cyanobacteria, Megan A. Rúa, Ashley N. Julian, Louise Stevenson

Biological Sciences Faculty Publications

Abstract Introduction Soils worldwide are degrading, raising concerns about our ability to feed the growing global population. Soil amendments that can alleviate degradation are gaining attention. The application of sediments dredged from waterways to agricultural fields has increasing promise as a means for improving degraded soils. However, herbaceous plant species may have difficulty establishing on dredged material because of low nutrient availability, inhibitory levels of toxins, unsuitable moisture conditions and lack of microorganisms capable of ameliorating these characteristics. To counteract these issues, we sought to understand if the use of a cover crop would increase the abundance, diversity and function …

Associations Between Preweaning Calf Feeding Behaviors With Age At First Calving And Lactational Performance Using An Automatic Calf Feeder, Turner H. Swartz, Christina Petersson-Wolfe

Dairy Science and Food Science Faculty Publications: 2022 to Present

The objective of this retrospective observational study was to determine whether preweaning calf behaviors and milk replacer (MR) intake from an automatic calf feeder were associated with age at first calving and first-lactation performance. Calves were housed in groups with access to an automatic calf feeder for 7 wk with a maximum milk allowance of 1,800 g/d of MR (12 L/d). Outcomes of interest included age at first calving (n = 137), first-lactation mature-equivalent 305-d (ME305) milk yield (n = 132), and first-lactation ME305 energy-corrected milk (ECM) yield (n = 132). Linear models included the fixed effects of the daily …

Utilisation Des Approches De Segmentation Du Public Pour Renseigner Les Programmes Intégrés De Planification Familiale Et De Santé Maternelle Au Niger, Breakthrough Research

Sexual and Reproductive Health, Rights, and Choices

Comprendre les déterminants comportementaux spécifiques et les obstacles à la recherche de services de santé reproductive et maternelle est essentiel dans l’élaboration des programmes de changement social et comportemental (CSC) pouvant mieux répondre aux besoins de la communauté. Les interventions CSC efficaces peuvent intégrer la segmentation du public, la pratique consistant à diviser un public en sous[1]groupes basés sur des facteurs démographiques, psychographiques et/ou comportementaux pour développer des approches CSC sur mesure qui sont les plus susceptibles de trouver écho parmi chaque sous-groupe du public. Ce dossier présente les résultats de l’étude des profils du public pour les femmes en …

Spectrum, Volume 50, Issue 5, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: A Slice of Politics with Senator Blumenthal -- MSU the Target of Another Mass Shooting in 2023 -- Car Break-Ins Affecting SHU Students -- Opportunities with iHub -- An Internship that Gives Back to the Community -- Student Nurses Helping Make a Change -- Men’s Volleyball Makes Statement NEC Win

The Policy Environment Of Self-Care: A Case Study Of The Philippines, Leonardo Jaminola Iii, Jana Marie Negre, Veincent Christian F. Pepito, Arianna Maever Loreche, Manuel M. Dayrit

Ateneo School of Medicine and Public Health Publications

Self-care is the ability and empowerment of individuals to maintain health through informed health-care decisions, with or without the support of a health provider. High-income countries have made advances to their conceptualization, research and institutionalization of self-care, given its reported benefits to patients, the health system and economy. A similar undertaking in low- and middle-income countries (LMICs) with already fragile health systems is warranted as highlighted by the coronavirus disease 2019 pandemic. Our article therefore aimed to describe and analyse the policy environment of self-care using the Philippines as a case study, which may have relevance to other similar countries …

Reproducibility And Determinants Of The Metabolic Responses During A Mixed-Meal Tolerance Test, Emma J. Stinson, Paolo Piaggi, Cassie M. Mitchell, Leanne M. Redman, Jonathan Krakoff

Clinical Research Faculty Publications

Objective: The aim of this study was to assess the reproducibility and physiological determinants of mixed-meal tolerance tests (MMTTs) on glucose and insulin responses. Methods: While inpatients on a weight-maintaining diet, 894 individuals (574 with normal and 267 with impaired glucose regulation and 53 with type 2 diabetes [T2D]) underwent 9-hour MMTTs (breakfast and lunch; 30% weight-maintaining diet each; 40% carbohydrate, 40% fat, and 20% protein). Total/incremental areas under the curve (AUC/iAUC) were calculated from MMTT plasma glucose/insulin concentrations. Acute insulin response (AIR) was quantified by intravenous glucose tolerance test and insulin action (M) via hyperinsulinemic-euglycemic clamp. A subset had …

Slo Coffee Co., Catherine Yoshida

Graphic Communication

SLO Coffee Co. is a fictional coffee brand based out of San Luis Obispo, California. Specifically, I focus on the creation of a comprehensive, intentional brand that includes a logo, the designs of three coffee bags, and an Instagram page, all of which are emphasized by grounding a brand through beautiful and deliberate graphics. SLO Coffee Co. branding targets a younger demographic and residents of San Luis Obispo. This is achieved through the implementation of brighter colors, fun and playful typefaces, and graphics that communicate the essence of San Luis Obispo and beloved local spots.

A local coffee brand based …

Muhlenberg Magic, Lehigh Valley Health Network

LVHN documents

No abstract provided.

Recent Advances And Challenges In Implementing Ipm Programmes In The Entomological Context Of Indian Agriculture, Ruchika Geedi, Gadi V.P. Reddy

Faculty Publications

Integrated pest management (IPM) programmes are based on using multiple methods to maintain nuisance insects below tolerant levels in crop fields. Recent advances in IPM in developed countries have incorporated biological pesticides, microbial products, semiochemicals, and beneficial insects, but few of such programmes have been successfully implemented in developing countries, such as India. Semiochemicals play critical roles as signals in various interspecific and intraspecific interactions between insects and plants, and among interacting insects, plants, and microbes. In India IPM programmes have included mechanical, chemical, cultural, and biological management strategies. However, among these methods, biological management has its own limitations. Indian …

Effects Of Other People's Facial Emotional Expression On Consumers’ Perceptions Of Chocolate Chip Cookies Containing Cricket Protein, Yupeng Gao, Pitchayapat Chonpracha, Bin Li, Witoon Prinyawiwatkul

Faculty Publications

Abstract: Edible insects are recognized as a potential alternative and sustainable source of high-quality protein for the human diet. Entomophagy is highly related to negative emotions that may cause reluctance to adopt insects as food in Western countries. During human interaction, a person's facial emotional expression (FEE) may influence other people's emotional responses. A person's emotional state may affect his/her food preference and food choice. Understanding how other people's FEE would affect consumers’ emotional profiles, liking, and subsequent willingness to try (WTT) and purchase intent (PI) toward insect-containing food products may help increase the acceptance of entomophagy. This study identified …

Physical Activity And Weight Loss In A Pragmatic Weight Loss Trial, Peter T. Katzmarzyk, Emily F. Mire, Corby K. Martin, Robert L. Newton, John W. Apolzan, Kara D. Denstel, William D. Johnson, Phillip Brantley, Ronald Horswell, Benjamin F. Springgate, Terry C. Davis, Connie L. Arnold, Eboni Price-Haywood, Carl J. Lavie, Vivian A. Fonseca, Tina K. Thethi, Jonathan Gugel, Kathleen B. Kennedy, Daniel F. Sarpong

Clinical Research Faculty Publications

The purpose of this study was to determine the association between changes in physical activity and changes in body weight in a cluster-randomized weight loss trial conducted in an underserved population in Louisiana. This study reports analyses conducted in the intervention group only, which was a 24-month multi-component weight loss program delivered by health coaches embedded in primary care clinics. Physical activity was assessed at baseline and at 6, 12, and 24 months of follow-up and changes in body weight were expressed as percent weight change from baseline. Among the sample of 402 patients, percent changes in body weight (mean …

Electronic Cigarette Nicotine Flux, Nicotine Yield, And Particulate Matter Emissions: Impact Of Device And Liquid Heterogeneity, Eric K. Soule, Shannon Mayne, William Snipes, Elizabeth K. Do, Travis Theall, Christoph Höchsmann, Soha Talih, Corby K. Martin, Thomas Eissenberg, Bernard F. Fuemmeler

Clinical Research Faculty Publications

Introduction: Electronic cigarettes (ECIGs) heat a nicotine-containing liquid to produce an inhalable aerosol. ECIG power (wattage) and liquid nicotine concentration are two factors that predict nicotine emission rate ("flux"). These factors can vary greatly across devices and users. Aims and Methods: The purpose of this study was to examine ECIG device and liquid heterogeneity in "real world"settings and the association with predicted nicotine flux, nicotine yield, and total particulate matter (TPM) emissions. Past 30-day ECIG users (n = 84; mean age = 23.8 years [SD = 9.6]) reported device and liquid characteristics. Device power was measured via multimeter, device display …

Bioelectrical Impedance Phase Angle Is Associated With Physical Performance Before But Not After Simulated Multi-Stressor Military Operations, Alyssa N. Varanoske, Melissa N. Harris, Callie Hebert, Neil M. Johannsen, Steven B. Heymsfield, Frank L. Greenway, Arny A. Ferrando, Jennifer C. Rood, Stefan M. Pasiakos

Clinical Research Faculty Publications

Physical performance decrements observed during multi-stressor military operations may be attributed, in part, to cellular membrane dysfunction, which is quantifiable using phase angle (PhA) derived from bioelectrical impedance analysis (BIA). Positive relationships between PhA and performance have been previously reported in cross-sectional studies and following longitudinal exercise training programs, but whether changes in PhA are indicative of acute decrements in performance during military operations is unknown. Data from the Optimizing Performance for Soldiers II study, a clinical trial examining the effects of exogenous testosterone administration on body composition and performance during military stress, was used to evaluate changes in PhA …

Sibling Resemblance In Physical Activity Levels: The Peruvian Sibling Study On Growth And Health, Carla Santos, José Maia, Sara Pereira, Olga Vasconcelos, Rui Garganta, J. Timothy Lightfoot, Go Tani, Donald Hedeker, Peter T. Katzmarzyk, Alcibíades Bustamante

Population and Public Health Science Faculty Publications

Physical activity is associated with a host of positive health outcomes and is shaped by both genetic and environmental factors. We aim to: (1) estimate sibling resemblance in two physical activity phenotypes [total number of steps∙day⁻¹ and minutes for moderate steps per day (min∙day⁻¹)]; and (2) investigate the joint associations of individual characteristics and shared natural environment with intra-pair sibling similarities in each phenotype. We sampled 247 biological siblings from 110 nuclear families, aged 6–17 years, from three Peruvian regions. Physical activity was measured using pedometers and body mass index was calculated. In general, non-significant variations in …

Exercise Modifies Hypothalamic Connectivity And Brain Functional Networks In Women After Bariatric Surgery: A Randomized Clinical Trial, Carlos A.A. Merege-Filho, Saulo S. Gil, John P. Kirwan, Igor H. Murai, Wagner S. Dantas, Mariana P. Nucci, Bruno Pastorello, Alisson Padilha De Lima, Paulo R. Bazán, Rosa M.R. Pereira, Ana L. De Sá-Pinto, Fernanda R. Lima, Sonia M.D. Brucki, Roberto De Cleva, Marco A. Santo, Claudia Da Costa Leite, Maria Concepción García Otaduy, Hamilton Roschel, Bruno Gualano

Division of Basic Science Faculty Publications

Background: Obesity is a disease that may involve disrupted connectivity of brain networks. Bariatric surgery is an effective treatment for obesity, and the positive effects on obesity-related conditions may be enhanced by exercise. Herein, we aimed to investigate the possible synergistic effects of Roux-en-Y Gastric Bypass (RYGB) and exercise training on brain functional networks. Methods: Thirty women eligible for bariatric surgery were randomly assigned to a Roux-en-Y gastric bypass (RYGB: n = 15, age = 41.0 ± 7.3 years) or RYGB plus Exercise Training (RYGB + ET: n = 15, age = 41.9 ± 7.2 years). Clinical, laboratory, and brain …

Factors Influencing Consumers’ Willingness-To-Try Seafood Byproducts, Silvia Murillo, Ryan Ardoin, Witoon Prinyawiwatkul

Faculty Publications

With increasing global demand for seafood, seafood byproducts (SB) utilization can contribute to a more sustainable food supply chain through waste-to-value food product development. However, consumer perceptions of SB (e.g., fish skin and bones) are underexplored. Therefore, this study aims to evaluate some factors influencing consumers’ willingness-to-try seafood byproducts. An online survey was conducted in the USA regarding intervention of SB informational cues with N = 904 adult seafood consumers internationally. The proportion of consumers willing to try SB increased significantly (McNemar’s test, α = 0.05) from 47% to 68% after SB safety and health claims had been presented in …

Associations Between Moderate To Vigorous Physical Activity, Sedentary Behavior, And Depressive Symptomatology In Adolescents: A Prospective Observational Cohort Study, Chelsea L. Kracht, Sai S. Pochana, Amanda E. Staiano

Population and Public Health Science Faculty Publications

Background: More moderate to vigorous physical activity (MVPA) and less time in sedentary behavior (SB) may protect against poor mental health in adolescence. Depressive symptomatology may also influence adolescents’ own MVPA and SB. The aim of this study was to examine the bidirectional relationship between adolescent MVPA, SB, and depressive symptomatology using a longitudinal approach. Methods: Adolescents (10–16 y) were recruited for a prospective observational cohort. Depressive symptomatology was measured using the Short Mood and Feelings Questionnaire. Accelerometry was used to measure MVPA and SB. Adolescents were classified by meeting the MVPA guideline (≥60 min/d) and quartiles of SB time, …

Unhealthy Herds And The Predator–Spreader: Understanding When Predation Increases Disease Incidence And Prevalence, Robert L. Richards, Bret D. Elderd, Meghan A. Duffy

Faculty Publications

Disease ecologists now recognize the limitation behind examining host–parasite interactions in isolation: community members—especially predators—dramatically affect host–parasite dynamics. Although the initial paradigm was that predation should reduce disease in prey populations (“healthy herds hypothesis”), researchers have realized that predators sometimes increase disease in their prey. These “predator–spreaders” are now recognized as critical to disease dynamics, but empirical research on the topic remains fragmented. In a narrow sense, a “predator–spreader” would be defined as a predator that mechanically spreads parasites via feeding. However, predators affect their prey and, subsequently, disease transmission in many other ways such as altering prey population structure, …

Using A Mobile Food Pantry To Address The Food Insecurity Needs Of College Students, Madison Lapke, Barbara Stoecker, M. Craig Edwards, Janice Hermann

Journal of Human Sciences and Extension

Food insecurity is a prevalent issue throughout the United States, the state of Oklahoma, and on Oklahoma State University’s (OSU) Stillwater campus. Research has shown that college and university students tend to be more food insecure than national population averages and Stillwater’s food insecurity rates have been even higher. Mobile food pantries (MFP) generally have been effective in addressing food insecurity, but few studies have investigated their use to alleviate food insecurity among college students. Our Daily Bread Food and Resource Center (ODB) in Stillwater implemented an MFP on OSU’s campus. The present study surveyed students who utilized the MFP …

Factors Associated With Fathers’ Attendance In A Latino Family Obesity Prevention Program, Sayaka Nagao-Sato, Silvia Alvarez De Davila, Aysegul Baltaci, Roxana Linares, Alejandro Omar Peralta Reyes, Youjie Zhang, Ghaffar Hurtado Choque, Marla Reicks

Journal of Human Sciences and Extension

Community-based programs may contribute to Latino pediatric obesity prevention; however, attendance remains low. This study aimed to identify factors associated with Latino father/male caregiver attendance in family-based adolescent obesity prevention programs conducted as part of a randomized controlled trial. The study used cross-sectional data from 137 fathers in the program, involving eight weekly sessions to improve their children’s energy balance-related behaviors. Evaluation data were collected at baseline and post-intervention. Fathers in a waitlisted control group attended sessions after post-intervention data collection. Attendance patterns were identified using cluster analysis: consistently high attendance (50% of fathers), declining attendance (19%), and non-attendance (31%) …