Digital Commons Network^™

Evaluating Species-Specific Replenishment Solution Effects On Plant Growth And Root Zone Nutrients With Hydroponic Arugula (Eruca Sativa L.) And Basil (Ocimum Basilicum L.), Lauren L. Houston, Ryan W. Dickson, Matthew B. Bertucci, Trenton L. Roberts

Horticulture Faculty Publications and Presentations

Managing nutrients in recirculating solutions can be challenging in hydroponic production, and poor management practices can rapidly result in root zone nutrient imbalances in reduced yield. Using mass balance principles to formulate hydroponic replenishment solutions is a proposed strategy to reduce nutrient imbalances and the need to periodically replace the hydroponic solution. Objectives were to (1) formulate species-specific nutrient replenishment solutions for arugula (Eruca sativa L.) and basil (Ocimum basilicum L.) using mass balance principles and (2) evaluate the effects of using these replenishment solutions on plant growth and root zone nutrients over time. In the first experiment, …

Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation In Preterm Pigs, Line I Christiansen, Bo Holmqvist, Xiaoyu Pan, Kristine Holgersen, Sandy E H Lindholm, Nicole L Henriksen, Douglas G Burrin, David Ley, Thomas Thymann, Per Torp Sangild, Stanislava Pankratova

Faculty, Staff and Students Publications

Very preterm infants show low levels of insulin-like growth factor-1 (IGF-1), which is associated with postnatal growth restriction and poor neurologic outcomes. It remains unknown whether supplemental IGF-1 may stimulate neurodevelopment in preterm neonates. Using cesarean-delivered preterm pigs as a model of preterm infants, we investigated the effects of supplemental IGF-1 on motor function and on regional and cellular brain development. Pigs were treated with 2.25 mg/kg/d recombinant human IGF-1/IGF binding protein-3 complex from birth until day 5 or 9 before the collection of brain samples for quantitative immunohistochemistry (IHC), RNA sequencing, and quantitative PCR analyses. Brain protein synthesis was …

Celiac Disease Prevalence And The Characteristics Of Celiac Patients In The United Arab Emirates, Two Centers Study, Asma Hamed Alnababteh

Dissertations

Celiac Disease (CD) is a chronic autoimmune gastrointestinal disorder caused by genetic susceptibility to gluten and affects around 1% of the population worldwide. CD can occur at any age and is diagnosed by detecting specific serological biomarkers and histopathological changes in the duodenal biopsy. In the United Arab Emirates, there is a lack of studies describing CD in children or adults; this thesis aimed at researching the epidemiology of celiac disease in among the populations in the United Arab Emirates.

Two Studies were conducted to achieve the research objectives, study one was conducted in Cleveland Clinic Abu Dhabi (CCAD) and …

Maternal Vitamin B12 And D Status, Depression, And Dietary Intake And Neonatal Outcomes Following Bariatric Surgery, Amna Salem Al Mansoori

Dissertations

Bariatric surgery is a more effective approach than dieting for women with morbid obesity and can reduce comorbidities, such as hypertension and gestational diabetes, while improving fertility. Vitamins B₁₂ and D have essential roles in ensuring a healthy pregnancy and favorable neonatal outcomes. However, pregnancies following bariatric surgery may be complicated by micronutrient deficiencies, particularly of vitamins B₁₂ and D. This study aims to investigate vitamin B₁₂ and D status and neonatal outcomes in pregnant women who underwent sleeve gastrectomy or Roux-en-Y gastric bypass compared with those of women who did not. Additionally, the dietary intake and …

State: The Magazine Of Illinois State University, Spring 2023, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine

Effect Of Fishmeal Replacement With Dried Red Wigglers (Eisenia Fetida) Worm Meal On Growth And Feed Utilization, Production Efficiency, And Serum Biochemistry In Nile Tilapia (Oreochromis Niloticus) Fingerlings, Youssra M. El-Ouny, Sahya Maulu, Mohamed A.A. Zaki, Amira A. Helaly, Abdel Aziz M. Nour, Mohammed F. Elbasuini, Eman M.H. Labib, Riad H. Khalil, Ali H. Gouda, Amira A.A. Hessein, Marc Verdegem, Hala S. Khalil

School of Biological and Marine Sciences

This study investigated the effect of replacing fishmeal with red wigglers (Eisenia fetida) worm meal (RWWM) in the diet of Nile tilapia (Oreochromis niloticus) fingerlings. Red wigglers worms (RWW) were culture on a vegetable by-product medium, harvested and dried to obtain red wigglers worm meal. The fish (average weight ± SE: 7.70 ± 0.06 g) were fed with seven diets (30% crude protein and 7.5% crude lipid), in which fishmeal was replaced with 0%, 5%, 10%, 15%, 20%, 25%, and 30% RWWM. The fish was reared in 1000 L fiberglass tanks in a recirculating aquaculture system and were hand-fed twice …

Refugees Living With Dementia: Assessing The Barriers To Healthcare Access In Crisis-Affected Populations In Lebanon And Switzerland, And The Role Humanitarian Actors Have On Addressing Them, Pedro Gomez

Independent Study Project (ISP) Collection

As life expectancies increase in many places around the world, the prevalence of aging populations has increased. Consequently, increased numbers of people globally, especially in developing countries, have been diagnosed with conditions associated with old age. Dementia, a group of conditions associated with impaired cognitive functions, is among these. Notwithstanding, many developing countries have done poorly with regards to diagnosing and treating dementia, with some cultures not even having a word to describe the condition. (ADI 2022). The lack of a diagnosis and knowledge about dementia for some refugee communities has led to healthcare challenges in their host countries (Corfield …

The Global Anxiety Crisis In Teenagers And A Proposed School-Based Preventative Intervention Plan Focusing On Building Resilience In Children, Lia Darling

Independent Study Project (ISP) Collection

The impacts of the COVID-19 pandemic and climate change have significantly influenced teenagers, creating a global anxiety crisis. This paper discusses why and how the pandemic and climate crisis increased anxiety in teenagers and the ways that prevent anxiety disorders like building resilience in children. While there is much literature on the negative effects on mental well-being, few propose solutions. This paper discusses the urgent need for preventative interventions to decrease the risk of developing an anxiety disorder along with proposing a framework for a school-based intervention focusing on building resilience skills in children. The paper used a mix method …

The Archetype Of The Ocean In Balinese Culture, Ava Hull

Independent Study Project (ISP) Collection

An archetype is essential for expressing an understanding of symbols and adding depth to the meaning derived from everyday life. It is a connection of source and meaning through the lens of the human experience. In the case of the ocean, people all over the world turn to the sea as a source of healing and a symbol of the murkiness of the unconscious mind. This holds true for the people of Bali as their beautiful Island is in deep connection with the force of the ocean. From the everyday contact like fishing and relaxing at the beach, to the …

The Effects Of Stigma Against Hiv And Tuberculosis On Patient Mental Health And Healthcare-Seeking Behavior In Dharamshala, Isabel Powell

Independent Study Project (ISP) Collection

HIV and tuberculosis are highly impactful diseases in India, causing severe morbidity, mortality, and suffering for millions. The stigmatization of these diseases unnecessarily exacerbates suffering for those afflicted and their families, compounding to the existing physical and emotional burden of diagnosis. Individual interviews with healthcare workers were conducted at Delek Hospital and the Tibetan Children’s Village in order to identify the existence and effects of stigma in the Tibetan refugee population in Dharamshala. Respondents reported an extremely high burden of tuberculosis in the community, complicated by the refugee status and unique infrastructural challenges of the population. The burden of HIV …

Spatial Ecology And Habitat Preference Of Yellow-Spotted Monitors (Varanus Panoptes) At Lizard Island National Park, Qld, Australia, Ryan Snyder

Independent Study Project (ISP) Collection

Lizard Island National Park is an area of strong habitat diversity, especially given its small size. There are several distinct habitats represented, including open sclerophyll woodlands, mangrove swamps, dune grasslands, foothills elevations, and of course anthropogenically modified human habitats. The object of this study was to observe the abundances and behaviors of the yellow-spotted monitor lizard (V. panoptes) in each of these habitat settings to answer the question of which habitat type is preferred amongst V. panoptes in the landscape context of Lizard Island National Park.

Study transects were conducted over the course of one month measuring abundance of V. …

Impact Of Wildlife Provisioning On Species Diversity, Relative Frequency, And Richness In New South Wales, Alanah Cohen-Tigör

Independent Study Project (ISP) Collection

Wildlife provisioning and camera trapping are two recently evolving methods of conservation and wildlife management, aimed at protecting animals in the face of ever worsening climate change. Habitats are being destroyed by climate disruption, decreasing species diversity and abundance worldwide. It is imperative that methods of protecting species are developed to slow or reverse this era of extinction. By providing supplementary food and water to ecological communities, the hope is that species will have improved survivorship and reproduction, making them more resilient and resistant to population decline. Camera trapping is product of modern technology, allowing researchers to monitor species without …

What Makes A Family: How An Empowerment-Based Health Care Delivery Model Employs Family Planning To Positively Impact Families In Rural Maharashtra: A Study In Jamkhed, Ahmadneger, Sezin Sakmar

Independent Study Project (ISP) Collection

The paper examines how an empowerment-based health care delivery model employs family planning services to positively impact families in rural Maharashtra. Family planning services provide those with the ability to become pregnant the option to control their own reproductive lives, whether they choose in favor of or against having children. Contraceptive use advances people’s human rights to choose whether they want to bear children and how many children they want, and people should have the choice of their preferred contraceptive method. The paper examines this issue within the framework of the Comprehensive Rural Health Project’s Jamkhed Model. Through the Jamkhed …

Dairy & Development: An Investigation Into The Economic And Sociopolitical Dynamics Of Yak Cheesemaking In Nepal, Audrey Peiker

Independent Study Project (ISP) Collection

Cheesemaking in Nepal is full of love, passion, and creativity. What began as a Swiss development project in the 1950s has now grown into a full-fledged industry, providing jobs, creative outlets, and cultural expression for many. Nepal’s Dairy Development Corporation owns several factories throughout the country, setting the tone for the industry by establishing the standard price for milk and process for cheesemaking. From there, privately held factories innovate and compete, bringing new products to the market and increasing wages, but also struggle with consistency and reliability. Now, Nepal’s cheesemaking market is at a turning point—much of the herding population …

Tibetan Vegans In Diaspora, Ringzen Wangmo

Independent Study Project (ISP) Collection

Despite the Tsampa (Roasted Barley) eating culture and yak cheese merchandise in the market, the Tibetan culture is widely known as highly dependable on meat eating by non-Tibetans, little is known about the Tibetan Vegans officially known as karkyong. Overall vegetarianism is known and practiced in the Tibetan history throughout the centuries that’s what’s commonly known as vegan diets in modern society. But not known as Vegans in the Tibet then. This study also shed some light on Tibetan vegans in the diaspora and their journey of becoming vegan through interviews with restaurant owners, vegans, monks, nuns, and lay Tibetans …

On Site Healthcare, Amy Roden

Electronic Theses and Dissertations

A productive workforce and retention of employees is an essential part of a company’s reputation and elevation of the company to be the best to the workforce. Healthy and present employees are a key to this productive workforce. Transient workers in the pipeline construction are away from their families and loved ones and can struggle to stay healthy and find quality healthcare while working long hours multiple days a week. Employers on these job sites can help their employees by providing onsite healthcare. The research shows there is a lack of healthcare providers available, especially in more rural areas. The …

Failure Of Early Mycological Clearance In Hiv-Negative Cryptococcal Meningitis, Zhihui Su, Chongliang Luo, Kai Dai, Dasen Yuan, Bang-E Qin, Meifeng Gu, Junyu Liu, Yong Chen, Fuhua Peng, Ying Jiang

2020-Current year OA Pubs

BACKGROUND: Negative cerebrospinal fluid (CSF) cultures at 2 weeks after antifungal treatment (early mycological clearance [EMC]) should be a treatment goal of cryptococcal meningitis (CM). However, EMC in human immunodeficiency virus (HIV)-negative patients with CM is poorly understood.

METHODS: We conducted a retrospective review of medical records and 1-year follow-up of 141 HIV-negative patients with CM with an initial positive CSF culture for

RESULTS: Of 141 patients, 28 (19.9%) had EMC failure. The 1-year mortality rate was 5.7% (8/141). Multivariate analysis showed that non-amphotericin B (AmB)-based regimens, baseline log

CONCLUSIONS: EMC failure in HIV-negative CM is attributed to non-AmB-based therapy …

Pharmacokinetics Of Single Feeding Of Cannabidiol In Cattle: A Pilot Study, Haley Cornette

Honors College Theses

Cannabidiol (CBD) is a substance that has been used in complementary medicine for many years. However, modern medicine has little knowledge of how this substance is utilized and metabolized in ruminant animals. Regulations on quality assurance and use in animals are lacking, and CBD supplementation in livestock is not approved. If CBD supplements can be shown to be safe and effective, detection in the animal will be important for determining regulation of use. A withdrawal period can then be established to allow time for deterioration of product to safe levels before livestock products enter human markets. This study sought to …

Optimized Acute Treatment Of Migraine Is Associated With Greater Productivity In People With Migraine: Results From The Chronic Migraine Epidemiology And Outcomes (Cameo) Study., Dawn C Buse, Stephanie J. Nahas, Walter Buzz F Stewart, Cynthia E Armand, Michael L Reed, Kristina M Fanning, Aubrey Manack Adams, Richard B Lipton

Department of Neurology Faculty Papers

OBJECTIVE: This study aimed to ascertain whether level of optimization of acute treatment of migraine is related to work productivity across the spectrum of migraine.

METHODS: Data were from the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study, an internet-based longitudinal survey. Respondents with migraine who reported full-time employment and use of ≥1 acute prescription medication for migraine were included. We determined relationships among lost productive time (LPT; measured with the Migraine Disability Assessment Scale), acute treatment optimization (Migraine Treatment Optimization Questionnaire- ), and monthly headache days (MHDs).

RESULTS: There was a direct relationship between LPT and MHD category. Greater acute …

Rocscholar Annual Report 2022, Lisa M. Buda

Rochester Regional Health authored publications and proceedings

RocScholar is the institutional repository (IR) for Rochester Regional Health (RRH) and is managed by the Libraries at RRH. It provides storage and access for RRH’s research and scholarly activity. This report highlights the repository’s second year of implementation.

Fit24, A Digital Health Intervention To Reduce Type 2 Diabetes Risk Among Hispanic Youth: Protocol For A Feasibility Pilot Study, Erica G Soltero, Callie Lopez, Salma M Musaad, Teresia M O'Connor, Debbe Thompson

Faculty, Staff and Students Publications

BACKGROUND: Poor physical activity (PA) and sleep behaviors in Hispanic adolescents contributes to increased risk for type 2 diabetes. Commonly owned digital devices and services like smartphones and text-messaging are highly used among adolescents and are promising intervention tools for reaching this age group. Personal activity trackers assess activity and sleep, making them ideal tools for addressing these behaviors. We propose to examine the feasibility of a 12-week intervention that uses theoretically grounded text messages and a Fitbit device to improve PA and sleep among Hispanic adolescents with obesity, as compared to a wait-list control group with a Fitbit device …

Quantifying The Number Of Us Men With Erectile Dysfunction Who Are Potential Candidates For Penile Prosthesis Implantation, Sirikan Rojanasarot, Abimbola O Williams, Natalie Edwards, Mohit Khera

Faculty, Staff and Students Publications

INTRODUCTION: Penile prosthesis implantation (PPI) is a treatment option recommended in clinical guidelines for erectile dysfunction (ED). However, a limited number of urologists perform PPI procedures in the United States.

AIM: To quantify the number of insured men with ED in the United States and project the number of potential candidates for PPI in 2022.

METHODS: An Excel-based disease impact model was constructed using a top-down estimation approach. The starting US male population consisted of adult men from 2022 US Census data after exclusion of age-specific mortality rates from the National Vital Statistics Reports. Men with health insurance were included …

Pilot Clinical Trial Of Macimorelin To Assess Safety And Efficacy In Patients With Cancer Cachexia, Megan Herodes, Lindsey J Anderson, Samuel Shober, Ellen A Schur, Solomon A Graf, Nicola Ammer, Ramiro Salas, Marco Marcelli, Jose M Garcia

Faculty, Staff and Students Publications

BACKGROUND: Cancer cachexia is associated with reduced body weight, appetite and quality of life (QOL) with no approved treatments. Growth hormone secretagogues like macimorelin have potential to mitigate these effects.

METHODS: This pilot study assessed the safety and efficacy of macimorelin for 1 week. Efficacy was defined a priori as 1-week change in body weight (≥0.8 kg), plasma insulin-like growth factor (IGF)-1 (≥50 ng/mL) or QOL (≥15%). Secondary outcomes included food intake, appetite, functional performance, energy expenditure and safety laboratory parameters. Patients with cancer cachexia were randomized to 0.5 or 1.0 mg/kg macimorelin or placebo; outcomes were assessed non-parametrically.

RESULTS: …

Social Disadvantage During Pregnancy: Effects On Gestational Age And Birthweight, Joan L Luby, Sarah K England, Deanna M Barch, Barbara B Warner, Cynthia Rogers, Christopher D Smyser, Regina Triplett, Jyoti Arora, Tara A Smyser, George M Slavich, Peinan Zhao, Molly Stout, Erik Herzog, J Philip Miller

2020-Current year OA Pubs

OBJECTIVE: Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide.

STUDY DESIGN: Measures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight.

RESULTS: Among 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 …

Natural History Of Tango2 Deficiency Disorder: Baseline Assessment Of 73 Patients, Christina Y Miyake, Erica J Lay, Claudia Soler-Alfonso, Kevin E Glinton, Kimberly M Houck, Mustafa Tosur, Nancy E Moran, Sara B Stephens, Fernando Scaglia, Taylor S Howard, Jeffrey J Kim, Tam Dam Pham, Santiago O Valdes, Na Li, Chaya N Murali, Lilei Zhang, Maina Kava, Deane Yim, Cheyenne Beach, Gregory Webster, Leonardo Liberman, Christopher M Janson, Prince J Kannankeril, Samantha Baxter, Moriel Singer-Berk, Jordan Wood, Samuel J Mackenzie, Michael Sacher, Lina Ghaloul-Gonzalez, Claudia Pedroza, Shaine A Morris, Saad A Ehsan, Mahshid S Azamian, Seema R Lalani

Faculty, Staff and Students Publications

PURPOSE: TANGO2 deficiency disorder (TDD), an autosomal recessive disease first reported in 2016, is characterized by neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, and life-threatening metabolic and cardiac crises. The purpose of this study was to define the natural history of TDD.

METHODS: Data were collected from an ongoing natural history study of patients with TDD enrolled between February 2019 and May 2022. Data were obtained through phone or video based parent interviews and medical record review.

RESULTS: Data were collected from 73 patients (59% male) from 57 unrelated families living in 16 different countries. The median age of participants at …

Prevalence, Hematological Parameters, And Coagulation Profiles: Cardiovascular Diseases Statistics In The Asir Region, Saudi Arabia, Kholoud N. Almetairi, Sultan Z. Alasmari, Mohammed H. Makkawi, Ahmad A. Shaikh

Saudi Medical Journal

Objectives: To determine the prevalence of cardiovascular disease (CVD) types in the Asir region of Saudi Arabia and the importance of hematological testing for CVD patients in the context of disease management. Methods: This retrospective study comprised 416 CVD patients, and samples were divided based the type of CVD. The Mann Whitney U test was used to compare patients’ hematological markers and coagulation profiles to those of healthy controls. Results: The rate of ischemic heart disease (IHD) was 80.7% that of other CVDs, and the rate of ST-elevation myocardial infarction (STEMI) was 37.3% the rate of CVD. Significant differences were …

Cellular Resistance Mechanisms In Cancer And The New Approaches To Overcome Resistance Mechanisms Chemotherapy, Ali A. Rabaan

Saudi Medical Journal

Despite major advancements in cancer healing approaches over the last few decades, chemotherapy remains the most popular malignancy treatment. Chemotherapeutic drugs are classified into many kinds based on their mechanism of action. Multidrug resistance (MDR) is responsible for approximately 90% of fatalities in malignancy cases treated with standard chemotherapeutics or innovative targeted medicines. Many innovative prospective anti-cancer medicines displayed high anti-cancer efficacy in a single application. However, combining them with other medications improves cancer treatment efficacy. This supports the belief that a combination of drugs is significantly more effective than a single medicine. Due to the intricacy of MDR processes …

Vitamin D Status Among Residents Of Molidawa Daur Autonomous Banner, Inner Mongolia, North China, Jingwen Hu, Yunmei Liang, Guiping Wen, Dezhong Chen, Yuanjing Liu, Hongmei Zhang, Xiaosong Qin

Saudi Medical Journal

Objectives: To retrospectively analyze the vitamin D (VD) status of residents in northeastern Inner Mongolia and its relationship with the average monthly sunshine hours. Methods: Serum 25-hydroxyvitamin D[s-25(OH)D] samples from 4982 outpatients (2092 males) in Moli Dawa Daur Autonomous Banner People’s Hospital, Hulunbuir, China from July 2018 to January 2022 were included in this study. Results: The overall median s-25(OH)D was 53.3 nmol/L, VD deficiency (<30 nmol/L), deficiency (30-50 nmol/L), sufficient (>50-250 nmol/L) and excess (>250 nmol/L) were 16% (796/4982), 30% (1495/4982), 53.4% (2658/4982) and 0.7% (33/4982). There were statistically significant differences in median s-25(OH)D by month, age-groups and gender ( p <0.001). Low VD status (LVDS, including VD deficiency and insufficiency) in females was 54.6% and males was 33.9%, and the LVDS composition differed significantly by age-group and month ( p <0.05). The changing trend of the median s-25(OH)D level was similar to the monthly average sunshine hours, with a slight lag. Conclusion: Nearly half of residents live in LVDS. LVDS is affected by month, gender, and age.

The Global Health Architecture: Governance And International Institutions To Advance Population Health Worldwide, Lawrence O. Gostin, Eric A. Friedman, Alexandra Finch

Georgetown Law Faculty Publications and Other Works

Policy Points Global health institutions and instruments should be reformed to fully incorporate the principles of good health governance: the right to health, equity, inclusive participation, transparency, accountability, and global solidarity. New legal instruments, like International Health Regulations amendments and the pandemic treaty, should be grounded in these principles of sound governance. Equity should be embedded into the prevention of, preparedness for, response to, and recovery from catastrophic health threats, within and across nations and sectors. This includes the extant model of charitable contributions for access to medical resources giving way to a new model that empowers low- and middle-income …

Corticosteroids Increase The Risk Of Invasive Fungal Infections More Than Tumor Necrosis Factor-Alpha Inhibitors In Patients With Inflammatory Bowel Disease, Martin H Gregory, Andrej Spec, Dustin Stwalley, Anas Gremida, Carlos Mejia-Chew, Katelin B Nickel, Matthew A Ciorba, Richard P Rood, Margaret A Olsen, Parakkal Deepak

2020-Current year OA Pubs

BACKGROUND: Invasive fungal infections are a devastating complication of inflammatory bowel disease (IBD) treatment. We aimed to determine the incidence of fungal infections in IBD patients and examine the risk with tumor necrosis factor-alpha inhibitors (anti-TNF) compared with corticosteroids.

METHODS: In a retrospective cohort study using the IBM MarketScan Commercial Database we identified US patients with IBD and at least 6 months enrollment from 2006 to 2018. The primary outcome was a composite of invasive fungal infections, identified by ICD-9/10-CM codes plus antifungal treatment. Tuberculosis (TB) infections were a secondary outcome, with infections presented as cases/100 000 person-years (PY). A …