Digital Commons Network^™

Understanding The Antiproliferative Activity Of Plant Extracts, Abigail Bastian, Parker Fryer, Sadie Gilmeister, Jackson Hofland, Blake Johnson, Lauren Jurrens, Keziah Knudson, Madeline Kvatek, Erika Mckenney, Abigail Noonan, Alexa Olguin, Emily Schmidt, Martha Stein, Anneka Sterk, Sophie Swart, Jonas Tiensvold, Alaena Trevino

Celebration of Research

Many plants possess medicinal properties. Some, such as the Pacific yew, have yielded chemotherapeutic drugs (taxanes). Scientists report that other extracts such as the leaves of Calendula officinalis (marigold), Vinca rosea (periwinkle), Viscum cruciatum (mistletoe), and Rosmarinus officinalis (rosemary) have anti-tumor activity. In most cases, the chemical components responsible for antiproliferative activity have not been identified and it is unclear if any individual components are as effective in isolation as they are in the context of the whole extract. Furthermore, in most cases, there are no data indicating whether these extracts have synergistic effects or cause negative reactions when used …

Does Insulin Resistance (Ir) Have An Impact On The Reproductive And Fertility Potential In Polycystic Ovary Syndrome (Pcos) Women? : Review Article, Muhjah Falah Hassan, Mufedah Ali Jawad, Rabab Zahir Al-Yasiry

Maaen Journal for Medical Sciences

Backgrounds: Polycystic ovary syndrome is the most common endocrine and reproductive disorder in the reproductive-age women. Among the pathological changes that are responsible for the development of polycystic ovary syndrome (PCOS), hyperinsulinemia due to increased insulin resistance (IR) is common and usually associated with a higher rate of ovulatory dysfunction and sub-fertility. In addition, those women have poor quality oocytes with low fertilization capability and poor quality embryos. So, insulin has a role in the reproductive function and fertility potential of reproductive age women. Conclusion: Females with PCOS usually exhibit an extreme difficulty in achieving either a successful spontaneous or …

Empowering Community Health Workers In Guatemala, Grace Sibert

Liberty University Research Week

Undergraduate

Applied

Exploration Of Health Outcomes Among Rural And Indigenous Populations In Guatemala, David Abafi

Liberty University Research Week

Graduate

Applied

Patient And Provider Experience With Artificial Intelligence Screening Technology For Diabetic Retinopathy In A Rural Primary Care Setting, Brian M. Nolan, Emma R. Daybranch, Kerri Barton, Neil Korsen

Journal of Maine Medical Center

Introduction: The development of autonomous artificial intelligence for interpreting diabetic retinopathy (DR) images has allowed for point-of-care testing in the primary care setting. This study describes patient and provider experiences and perceptions of the artificial intelligence DR screening technology called EyeArt by EyeNuk during implementation of the tool at Western Maine Primary Care in Norway, Maine.

Methods: This non-randomized, single-center, prospective observational study surveyed 102 patients and 13 primary care providers on their experience of the new screening intervention.

Results: All surveyed providers agreed that the new screening tool would improve access and annual screening rates. Some providers also identified …

A Cascade Of Care Of Patients With Hepatitis C Infection In A Rural State, Wollelaw Agmas, Wendy Craig, Kathleen Fairfield, Brian F. King, Elizabeth Eisenhardt, Kinna Thakarar

Journal of Maine Medical Center

Introduction: The substance misuse epidemic has fueled an increase in hepatitis C virus (HCV) infections. Despite the availability of sensitive screening and curative treatment, relatively few people are aware of their diagnosis and engaged in care. In this study, we aimed to identify local gaps in HCV care and inform strategies for improvement.

Methods: In this retrospective study, we assessed adult patients seen at a tertiary care center from 2015 to 2019 and who were eligible for HCV screening based on recommendations from the Centers for Disease Control and Prevention. Inclusion criteria were birth from 1945 to 1965, long-term dialysis …

The Sound Of The Civil War: Examining The Intersection Between Music And Emotion In America, 1861-1865, Christina Cannon

Campus Research Month

The topics of the history of music and the history of music intersect in the Civil War in fascinating ways. Both religious music and “secular” music were seen to have great power over their listeners, potentially with the power to alter the directions of lives or their salvation status. Music was used both as a mode of rebellion against the antagonizing army and ideal and a rebellion against unnecessarily violent acts. Each side used it against the other, but a select few also used it against the war itself. Soldiers marched to music, set camp to music, and fought to …

Traditional Cattle Feeding Stuffs: Fatty Acid Profile, A. M. Peres, L. Dias, J. Sá Morais, F. Sousa, J. M. Pires

IGC Proceedings (1977-2023)

Dietary polyunsaturated fatty acids (PUFA) are perceived to be healthier than saturated fatty acids. Therefore, in order to be able to manipulate the fatty acid profile of meat and/or milk, to respond to the consumer demands, knowledge of the fatty acid profile of feeding stuffs for cattle is of major importance (LeDoux et al., 2002; Petit, 2002). In this work a preliminary study was made of the fatty acid profile of the cow's diet in a traditional farm production system.

Finishing Effect On Fatty Acid Profile Of Intramuscular Fat In Extensively Reared Steers, N. Aldai, B. E. Murray, A. I. Nájera, K. Osoro

IGC Proceedings (1977-2023)

Both the amount and the composition of fat depots in beef may be influenced by several factors i.e. feeding system. Related to this factor, extensively reared cattle may produce beef with a more desirable fatty acid (FA) composition in terms of beneficial effect on human health, especially in relation to the content of n-3 type FAs. However, concentrate finishing improves some carcass traits and meat quality. In this sense, the objective of this work was to study the effect of concentrate finishing on intramuscular (IM) FA profile of Longissimus thoracis (LT) muscle in pasture fed steers.

Effect Of Perennial Ryegrass Cultivars On The Fatty Acid Composition In Milk Of Stall-Fed Cows, Anjo Elgersma, H. J. Smit, G. Ellen, S. Tamminga

IGC Proceedings (1977-2023)

Herbage provides bulk feed for ruminants and plant lipids, especially C18:3, are a major source of benefical fatty acids (FA) in milk. There are very few direct comparisons allowing a precise evaluation of the effects of the basal forage diet on milk FA composition. Grass quality differences can affect rumen metabolism and there could be opportunities to change the composition of ruminant products through choice of grass cultivar. To test this hypothesis, six cultivars were fed to dairy cows in a stall-feeding trial with fresh grass to evaluate the effect of grass cultivar on rumen VFA and milk FA composition …

Antioxidative Activities Of Alfalfa And Timothy Varieties, J. K. Lee, H. S. Park, J. G. Kim, B. H. Paek, J. H. Fike

IGC Proceedings (1977-2023)

The term "functional foods" is often used as a generic description for the beneficial effects of ingested foods that go beyond their traditional nutritive value (Bauman et al., 2001). Milk and dairy products are important dietary sources of nutrients, providing energy, high quality protein, and a variety of vitamins and minerals. Recent research has focused on altering the fat and protein content of milk and other dairy products in order to improve their nutrient content to more aptly reflect current dietary recommendations and trends. As a result, additional focus is being given to designing foods that have beneficial effects …

Forage Yield And Nutritive Value Of 30 Cultivars Of Maize For Silage In The Highland Valleys Of Central Mexico, G. Tovar, J. L. Arellano, M. E. Sosa, C. Sánchez, H. P. Pérez, E. Vera, U. M. Vera, J. I. Vázquez

IGC Proceedings (1977-2023)

In Mexico, the selection of maize cultivars for forage has mainly been based on dry matter (DM) yields, not considering nutritional quality as an important evaluation parameter. The objective of this study was to assess forage yield and nutritive value of Highland and Subtropical maize cultivars for silage in the Highland Valleys of Central México.

April 2023 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.

Mitigation Of Heat Stress In Striped Catfish (Pangasianodon Hypophthalmus) By Dietary Allicin: Exploring The Growth Performance, Stress Biomarkers, Antioxidative, And Immune Responses, Mohamed A. Mahmoud, Manal S. Kassab, Amr I. Zaineldin, Asem A. Amer

Faculty Journal Articles

No abstract provided.

Learning In A Virtual Environment To Improve Type 2 Diabetes Outcomes: Randomized Controlled Trial, Constance M Johnson, Gail D'Eramo Melkus, Louise Reagan, Wei Pan, Sathya Amarasekara, Katherine Pereira, Nancy Hassell, Sarah Nowlin, Allison Vorderstrasse

Faculty, Staff and Student Publications

Background: Given the importance of self-management in type 2 diabetes mellitus (T2DM), a major aspect of health is providing diabetes self-management education and support. Known barriers include access, availability, and the lack of follow through on referral to education programs. Virtual education and support have increased in use over the last few years.

Objective: The purpose of the Diabetes Learning in a Virtual Environment (LIVE) study was to compare the effects of the LIVE intervention (educational 3D world) to a diabetes self-management education and support control website on diet and physical activity behaviors and behavioral and metabolic outcomes in adults …

Responses To Many Anti-Aging Interventions Are Sexually Dimorphic., Andrzej Bartke, Erin Hascup, Kevin Hascup

Articles

There is increasing appreciation that sex differences are not limited to reproductive organs or traits related to reproduction and that sex is an important biological variable in most characteristics of a living organism. The biological process of aging and aging-related traits are no exception and exhibit numerous, often major, sex differences. This article explores one aspect of these differences, namely sex differences in the responses to anti-aging interventions. Aging can be slowed down and/or postponed by a variety of environmental ("lifestyle"), genetic or pharmacological interventions. Although many, particularly older studies utilized only one sex of experimental animals, there is considerable …

Responses To Many Anti-Aging Interventions Are Sexually Dimorphic., Andrzej Bartke, Erin Hascup, Kevin Hascup

Articles

There is increasing appreciation that sex differences are not limited to reproductive organs or traits related to reproduction and that sex is an important biological variable in most characteristics of a living organism. The biological process of aging and aging-related traits are no exception and exhibit numerous, often major, sex differences. This article explores one aspect of these differences, namely sex differences in the responses to anti-aging interventions. Aging can be slowed down and/or postponed by a variety of environmental ("lifestyle"), genetic or pharmacological interventions. Although many, particularly older studies utilized only one sex of experimental animals, there is considerable …

A Primer For The Student Joining The General Thoracic Surgery Service Tomorrow: Primer 2 Of 7., Colin C. Yost, Rohun Bhagat, David Blitzer, Clauden Louis, Jason Han, Fatima G Wilder, Robert A Meguid

Student Papers, Posters & Projects

This medical student primer discusses general thoracic surgery, which involves treating pathologies involving all structures in the thorax except the heart, thoracic aorta, great vessels, and spine.

Sustainable Diets: Improving Planetary And Population Health (Evidence Summary For Policymakers), C Pettinger

School of Health Professions

No abstract provided.

Interactions Between Metabolism And Growth Can Determine The Co-Existence Of Staphylococcus Aureus And Pseudomonas Aeruginosa, Camryn Pajon, Marla C. Fortoul, Gabriela Diaz-Tang, Estefania Marin Meneses, Ariane R. Kalifa, Elinor Sevy, Taniya Mariah, Brandon Toscan, Maili Marcelin, Daniella M. Hernandez, Melissa M. Marzouk, Allison J. Lopatkin, Omar T. Eldakar, Robert Smith

Biology Faculty Articles

Most bacteria exist and interact within polymicrobial communities. These interactions produce unique compounds, increase virulence and augment antibiotic resistance. One community associated with negative healthcare outcomes consists of Pseudomonas aeruginosa and Staphylococcus aureus. When co-cultured, virulence factors secreted by P. aeruginosa reduce metabolism and growth in S. aureus. When grown in vitro, this allows P. aeruginosa to drive S. aureus toward extinction. However, when found in vivo, both species can co-exist. Previous work has noted that this may be due to altered gene expression or mutations. However, little is known about how the growth environment could influence the …

Examining Youth Bicycle Programming Through The Empowerment- Based Youth Development Model, Thomas Clanton, Charles Chancellor, Harrison Pinckney, Venera Balidemaj

Journal of Youth Development

This study evaluates Momentum Bicycle Clubs (MBC) through the empowerment-based positive youth development framework (EMPYD). Data were collected through eight cross-sectional focus groups of MBC youth participants (ages 10-17). Sessions included three topics: the MBC program, the mentors, and the bicycle, all of which elucidated elements of an EMPYD program for analysis. The data were analyzed utilizing an interpretative phenomenological approach. The results of the focus groups revealed how MBC empowers its youth participants. MBC displayed characteristics of the EMPYD model by providing youth with opportunities to develop mastery and moral identity in addition to the 5Cs of positive youth …

Neoadjuvant Pembrolizumab In Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors, Kaysia Ludford, Won Jin Ho, Jane V Thomas, Kanwal P S Raghav, Mariela Blum Murphy, Nicole D Fleming, Michael S Lee, Brandon G Smaglo, Y Nancy You, Matthew M Tillman, Carlos Kamiya-Matsuoka, Selvi Thirumurthi, Craig Messick, Benny Johnson, Eduardo Vilar, Arvind Dasari, Sarah Shin, Alexei Hernandez, Xuan Yuan, Hongqui Yang, Wai Chin Foo, Wei Qiao, Dipen Maru, Scott Kopetz, Michael J Overman

Faculty, Staff and Student Publications

PURPOSE: Pembrolizumab significantly improves clinical outcomes in advanced/metastatic microsatellite instability high (MSI-H)/deficient mismatch repair (dMMR) solid tumors but is not well studied in the neoadjuvant space.

METHODS: This is a phase II open-label, single-center trial of localized unresectable or high-risk resectable MSI-H/dMMR tumors. Treatment is pembrolizumab 200 mg once every 3 weeks for 6 months followed by surgical resection with an option to continue therapy for 1 year followed by observation. To continue on study, patients are required to have radiographic or clinical benefit. The coprimary end points are safety and pathologic complete response. Key secondary end points are response …

Machine Learning-Based Routine Laboratory Tests Predict One-Year Cognitive And Functional Decline In A Population Aged 75+ Years, Karina Braga Gomes, Ramon Gonçalves Pereira, Alexandre Alberto Braga, Henrique Cerqueira Guimarães, Elisa De Paula França Resende, Antônio Lúcio Teixeira, Maira Tonidandel Barbosa, Wagner Meira Junior, Maria Das Graças Carvalho, Paulo Caramelli

Faculty, Staff and Student Publications

BACKGROUND: Cognitive and functional decline are common problems in older adults, especially in those 75+ years old. Currently, there is no specific plasma biomarker able to predict this decline in healthy old-age people. Machine learning (ML) is a subarea of artificial intelligence (AI), which can be used to predict outcomes Aim: This study aimed to evaluate routine laboratory variables able to predict cognitive and functional impairment, using ML algorithms, in a cohort aged 75+ years, in a one-year follow-up study.

METHOD: One hundred and thirty-two older adults aged 75+ years were selected through a community-health public program or from long-term-care …

Implementation Of Seasonal Diets Through Seasonal Diet Surveys In Sloth Bears (Melursus Ursinus): A Case Study At Idaho Falls Zoo, Noah Clever

Undergraduate Honors Thesis Projects

Wild sloth bears (Melursus ursinus) display seasonal diet preferences for insects and fruit during the dry and monsoon season respectively. To potentially utilize as a method for reducing abnormal behaviors and improving animal welfare, the purpose of the study is to survey zoos with captive sloth bears and determine if zoo-housed individuals display seasonal diet preferences. From May 18th, 2022 to March 2nd, 2023 data was collected on Priya, a sloth bear from Idaho Falls Zoo, and her preference for fruit and insects. Temperature, season, fruit choice based on sugar levels, and insect choice based on texture of …

Web-Based Cognitive Behavioral Intervention For Older Adult With Arthritis Fatigue; A Feasibility And Acceptability Study, Jeungok Choi, Miaomiao Shen, Rae Walker

Sigma Foundation for Nursing Research Grant Reports

The purpose of this project is to develop a web-based cognitive behavioral intervention (Web-CBI) and to test feasibility and acceptability of Web-CBI for older adults with arthritis fatigue.

Information Needs, Sources And Information Seeking Behaviour Of Poultry Farmers In Namakkal: A Survey, Pushpam P, Pushpam P

Library Philosophy and Practice (e-journal)

Agriculture has always been the backbone of the Indian economy, and the poultry industry is an essential part of it. In recent years, poultry farming has seen significant growth, particularly in the Namakkal district of Tamil Nadu. The purpose of this study is an investigation of information needs, information sources and information-seeking behaviour of Information (ISB) in Namakkal District. This study aims to explore the information needs, sources, and information-seeking behaviour of poultry farmers in the Namakkal district. The study will examine the types of information that farmers need, the sources they use to obtain this information, and their preferred …

Industrialization Of Tall Wheatgrass For Construction Of “Coastal Grass Belt”, Hongwei Li, Qi Zheng, Jianlin Wang, Hongyong Sun, Kexin Zhang, Hongman Fang, Xuerong Xing, Weicai Yang, Xiaofeng Cao, Xiaojing Liu, Haichun Jing, Kang Chong, Zhensheng Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

Tall wheatgrass (Elytrigia elongata) is a perennial cool-season bunchgrass with high productivity and tolerance to salt and alkali, waterlogging, and drought. Since first introduced into China in 1950s, tall wheatgrass has long been used as a wild parent for distant hybridization with wheat (Triticum aestivum). During 1980s─1990s, a few tall wheatgrass varieties were introduced to China as forage grass, nonetheless, currently they are still not widely cultivated and no variety was certificated. In 2020, Zhensheng Li put forward a proposal to construct “Coastal Grass Belt” on saline and alkaline soils in the Circum-Bohai sea region, which provides an opportunity for …

Mixed Depression In The Post-Covid-19 Syndrome: Correlation Between Excitatory Symptoms In Depression And Physical Burden After Covid-19, Alessio Simonetti, Evelina Bernardi, Stella Margoni, Antonello Catinari, Antonio Restaino, Valentina Ieritano, Marta Palazzetti, Federico Mastrantonio, Delfina Janiri, Matteo Tosato, Francesco Landi, Gabriele Sani

Faculty, Staff and Students Publications

The relationship between depression and post-COVID-19 disease syndrome (post-COVID-19 syndrome) is established. Nevertheless, few studies have investigated the association between post-COVID-19 syndrome and mixed depression, i.e., a specific sub-form of depression characterized by high level of excitatory symptoms. Aims of the present study are: (a) to compare the post-COVID-19 syndrome's burden in depressed and non-depressed patients, and (b) to investigate the correlation between post-COVID-19 syndrome's burden and the severity of mixed depression. One thousand and forty six (n = 1460) subjects with post-COVID-19 syndrome were assessed. Subjects were divided into those with (DEP) or without (CONT) depression. Sociodemographically, post-COVID-19 syndrome's …

Hybrids Between Meadow And Smooth Bromegrass: A New Forage Crop For Canada, B. E. Coulman, Y. S. N. Ferdinandez

IGC Proceedings (1977-2023)

Smooth bromegrass (Bromus inermis Leyss.) has been an important hay grass in the agricultural regions of western Canada for approximately 50 years. Meadow bromegrass (B. riparius Rehm.) has become the most important pasture species in this region over the last 15 years. It is possible to produce hybrids between these species, which could lead to the development of a type of bromegrass which would be useful for both hay and pasture purposes.

The Seasonal Nutritional Value Of Kikuyu Oversown With Ryegrass And Clover, Robin Meeske, Philip R. Botha, Hennie A. Snyman

IGC Proceedings (1977-2023)

To overcome the seasonality and relatively low forage quality of kikuyu (Pennisetum clandestinum), annual ryegrass (Lolium multiflorum spp.), perennial white (Trifolium repens) and red clover (Trifolium pratense) can be incorporated into an existing kikuyu stand to improve pasture quality and spring production. The aim of this study was to determine the quality of kikuyu (K), kikuyu oversown with annual ryegrass (KR), kikuyu oversown with a mixture of perennial ryegrass (Lolium perenne) and perennial white and red clover (KRC) and kikuyu oversown with a mixture of white and red clover (KC), in …