Digital Commons Network^™

Effectiveness Of Icosapent Ethyl On First And Total Cardiovascular Events In Patients With Metabolic Syndrome, But Without Diabetes: Reduce-It Metsyn, Michael Miller, Deepak L Bhatt, Eliot A Brinton, Terry A Jacobson, Philippe Gabriel Steg, Armando Lira Pineda, Steven B Ketchum, Ralph T Doyle, Jean-Claude Tardif, Christie M Ballantyne

Faculty, Staff and Students Publications

Aims: Metabolic syndrome (MetSyn) is associated with high risk of cardiovascular (CV) events, irrespective of statin therapy. In the overall REDUCE-IT study of statin-treated patients, icosapent ethyl (IPE) reduced the risk of the primary composite endpoint (CV death, non-fatal myocardial infarction, non-fatal stroke, coronary revascularization, or unstable angina requiring hospitalization) and the key secondary composite endpoint (CV death, non-fatal myocardial infarction, or non-fatal stroke).

Methods and results: REDUCE-IT was an international, double-blind trial that randomized 8179 high CV risk statin-treated patients with controlled LDL cholesterol and elevated triglycerides, to IPE 4 g/day or placebo. The current study evaluated the pre-specified …

Exploring Food And Physical Activity Behaviours Of Adolescents After Bariatric Surgery: A Qualitative Study, Baraa Osama Alries

Theses

In recent years, both globally and in the United Arab Emirates, adolescent obesity has emerged as a severe public health concern. Bariatric surgery is a viable treatment for adolescent obesity. However, an equally important aspect is examining the lifestyle changes, specifically concerning dietary habits and physical activity after this surgical intervention. Moreover, there is limited research on the postoperative nutrition-related nutritional and physical activity behaviors of adolescents after bariatric surgery globally, regionally, and in the UAE. The main aim of this study was to explore barriers and facilitators of diet and physical activity regimens of adolescents who had undergone bariatric …

Development And Psychometric Validation Of The Pandemic-Related Traumatic Stress Scale For Children And Adults, Courtney K. Blackwell, Phillip Sherlock, Kathryn L. Jackson, Julie A. Hofheimer, David Cella, Molly A. Algermissen, Akram N. Alshawabkeh, Lyndsay A. Avalos, Tracy Bastain, Clancy Blair, Michelle Bosquet Enlow, Patricia A. Brennan, Carrie Breton, Nicole R. Bush, Aruna Chandran, Shaina Collazo, Elisabeth Conradt, Sheila E. Crowell, Sean Deoni, Amy J. Elliott, Jean A. Frazier, Jody M. Ganiban, Diane R. Gold, Julie B. Herbstman, Christine Joseph, Margaret R. Karagas, Barry Lester, Jessica A. Lasky-Su, Leslie D. Leve, Kaja Z. Lewinn, W. Alex Mason, Elisabeth C. Mcgowan, Kimberly S. Mckee, Rachel L. Miller, Jenae M. Neiderhiser, Thomas G. O’Connor, Emily Oken, T. Michael O’Shea, David Pagliaccio, Rebecca J. Schmidt, Anne Marie Singh, Joseph B. Stanford, Leonardo Trasande, Rosalind J. Wright, Cristiane S. Duarte, Amy E. Margolis

Department of Child, Youth, and Family Studies: Faculty Publications

To assess the public health impact of the COVID-19 pandemic on mental health, investigators from the National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) research program developed the Pandemic-Related Traumatic Stress Scale (PTSS). Based on the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) acute stress disorder symptom criteria, the PTSS is designed for adolescent (13–21 years) and adult self-report and caregiver-report on 3–12-year-olds. To evaluate psychometric properties, we used PTSS data collected between April 2020 and August 2021 from non-pregnant adult caregivers (n = 11,483), pregnant/postpartum individuals (n = 1,656), …

Marine Mammals Of The Emirates: Whales, Dolphins, Porpoises And Dugongs, Ada Natoli, Shamsa Al Hameli

All Works

Marine mammals have always captured the imagination of the people they share their environment with, but few people know that various species populate the waters of the United Arab Emirates (UAE). The world’s second largest population of dugongs reside in the Abu Dhabi Emirate, while two species of dolphins (Indian Ocean humpback and Indo-Pacific bottlenose dolphin) and the elusive finless porpoises inhabit Abu Dhabi and Dubai waters. Facing both the Sea of Oman and the Arabian Gulf, the UAE hosts a total of 18 species of marine mammals. These include the biggest animal on Earth, the blue whale, Bryde’s, humpback …

Acute Hepatic Porphyrias: Recommendations For Diagnosis And Management With Real-World Examples, Akshata Moghe, Amy Dickey, Angelika Erwin, Rebecca K. Leaf, Alan O'Brien, John G. Quigley, Manish Thapar, Karl E. Anderson

Division of Gastroenterology and Hepatology Faculty Papers

Acute hepatic porphyria (AHP) is a group of four rare inherited diseases, each resulting from a deficiency in a distinct enzyme in the heme biosynthetic pathway. Characterized by acute neurovisceral symptoms that may mimic other medical and psychiatric conditions, lack of recognition of the disease often leads to a delay in diagnosis and initiation of effective treatment. Biochemical testing for pathway intermediates that accumulate when the disease is active forms the basis for screening and establishing a diagnosis. Subsequent genetic analysis identifies the pathogenic variant, supporting screening of family members and genetic counseling. Management of AHP involves avoidance of known …

Human Schwann Cells In Vitro I. Nerve Tissue Processing, Pre-Degeneration, Isolation, And Culturing Of Primary Cells, Gabriela I. Aparicio, Paula V. Monje

Markey Cancer Center Faculty Publications

This paper presents versatile protocols to prepare primary human Schwann cell (hSC) cultures from mature peripheral nervous system tissues, including fascicles from long spinal nerves, nerve roots, and ganglia. This protocol starts with a description of nerve tissue procurement, handling, and dissection to obtain tissue sections suitable for hSC isolation and culturing. A description follows on how to disintegrate the nerve tissue by delayed enzymatic dissociation, plate the initial cell suspensions on a two-dimensional substrate, and culture the primary hSCs. Each section contains detailed procedures, technical notes, and background information to aid investigators in understanding and managing all steps. Some …

Combatting A Crisis Of Global Food Protectionism Sparked By The War In Ukraine, Daniel C.K. Chow, Ian M. Sheldon

Vanderbilt Journal of Transnational Law

The world is currently gripped in a food crisis of historic proportions that is threatening tens of millions of people in the poorest countries of the world with famine and starvation. Sparked by the war in Ukraine, this crisis is being made worse by nations imposing export restrictions on food in a misguided attempt to curb soaring domestic food prices. Export restrictions are "beggar-thy-neighbor" policies that prevent increases in domestic food prices but at the expense of raising world prices, exacerbating the crisis. Although nations have turned to the World Trade Organization (WTO) for help in removing these export restrictions, …

A New Green Wave: Lessons From Argentina's Marea Verde For Legalizing Abortion Over Religious Opposition In The United States, Morgan Peck

Vanderbilt Journal of Transnational Law

This Note examines the role Christianity, particularly Roman Catholicism, played in influencing abortion laws in the United States and Argentina and offers a solution for new federal protections of abortion rights in the United States. Part II discusses the evolution of abortion rights in both countries, from their foundations to their recent reversals. Part III scrutinizes the ways in which religious ideology factored into the different logical frameworks utilized by the different parties involved in the fight for abortion access, the relevant tactics employed, and the subsequent outcomes. Considering the impact in Argentina of US jurisprudence regarding abortion rights, the …

Construction Of Esg Evaluation Index System Of State-Owned Listed Companies: Analysis Based On The Perspective Of Comprehensive Corporate Value, Yiping Sun

Dissertations and Theses Collection (Open Access)

In this paper, I explore the applicability of environmental, social, and governance (ESG) evaluation systems to Chinese state-owned enterprises (SOEs). I assess these ESG evaluation systems in terms of the overall value of Chinese SOEs and point out that these enterprises do not have their own evaluation system. Establishing an ESG system for Chinese SOEs can encourage them to disclose quantifiable indicators, thus objectively demonstrating their comprehensive ESG performance and helping to enhance their overall value. I examine the current ESG evaluation systems in detail and find that there are many problems in applying the main international evaluation systems to …

“It Takes A Village!”: Social Capital Building In A Remote Hawai‘I Community, Manca Sustarsic, Sothy Eng, Nancy Ooki, Heather Greenwood

Journal of Youth Development

In this cross-sectional study, we investigated the multi-level educational intervention among youth in a low-income, remote community in Hawai‘i, United States. The program aided with middle schoolers’ transition into adulthood through youth-adult partnerships, teen mentoring, and community sustainability. Drawing upon social capital framework, we explored participants’ experiences and how the intervention promoted positive developmental outcomes among the youth. We recruited youth from a rural Title I Middle School in Hawai‘i. Nine youth (n_boys=6, n_girls=3; M_age=13; 44.9% Native Hawaiian or Other Pacific Islander, 44.4% Black or African American, 33.3% White, 22.2. % Asian; participants …

State-Of-The-Art Document On Optimal Contemporary Management Of Cardiomyopathies, Petar M Seferović, Marija Polovina, Giuseppe Rosano, Biykem Bozkurt, Marco Metra, Stephane Heymans, Wilfried Mullens, Johann Bauersachs, Karen Sliwa, Rudolf A De Boer, Dimitrios Farmakis, Thomas Thum, Iacopo Olivotto, Claudio Rapezzi, Aleš Linhart, Domenico Corrado, Carsten Tschöpe, Ivan Milinković, Antoni Bayes Genis, Gerasimos Filippatos, Andre Keren, Milika Ašanin, Gordana Krljanac, Ružica Maksimović, Hadi Skouri, Tuvia Ben Gal, Brenda Moura, Maurizio Volterrani, Magdy Abdelhamid, Yuri Lopatin, Ovidiu Chioncel, Andrew J S Coats

Faculty, Staff and Students Publications

Cardiomyopathies represent significant contributors to cardiovascular morbidity and mortality. Over the past decades, a progress has occurred in characterization of the genetic background and major pathophysiological mechanisms, which has been incorporated into a more nuanced diagnostic approach and risk stratification. Furthermore, medications targeting core disease processes and/or their downstream adverse effects have been introduced for several cardiomyopathies. Combined with standard care and prevention of sudden cardiac death, these novel and emerging targeted therapies offer a possibility of improving the outcomes in several cardiomyopathies. Therefore, the aim of this document is to summarize practical approaches to the treatment of cardiomyopathies, which …

Nurses' Experiences And Perspectives Of The Telehealth Working Environment And Educational Needs, Stacee M. Lerret, Susan A. Nuccio, Alyssa Compton, Maria Keegan, Kathryn Rapala

College of Nursing Faculty Research and Publications

Background:

The continuing evolution of health care and the nursing profession includes the exponential growth of telehealth platforms. The goal of this study was to describe nurses' experiences with and perspectives on their practice with and future need for telehealth.

Method:

A cross-sectional descriptive mixed methods study was conducted with nursing graduates from a single university. Completed survey questions focused on demographics, current work status, plans for employment participation, and telehealth experience. Descriptive analysis was conducted with statistical software, with directed content analysis for narrative responses.

Results:

A total of 305 of 5,080 participants completed the survey (6% response rate). …

Untargeted Metabolomic Analysis Investigating Links Between Unprocessed Red Meat Intake And Markers Of Inflammation, Alexis C Wood, Goncalo Graca, Meghana Gadgil, Mackenzie K Senn, Matthew A Allison, Ioanna Tzoulaki, Philip Greenland, Timothy Ebbels, Paul Elliott, Mark O Goodarzi, Russell Tracy, Jerome I Rotter, David Herrington

Faculty, Staff and Students Publications

BACKGROUND: Whether red meat consumption is associated with higher inflammation or confounded by increased adiposity remains unclear. Plasma metabolites capture the effects of diet after food is processed, digested, and absorbed, and correlate with markers of inflammation, so they can help clarify diet-health relationships.

OBJECTIVE: To identify whether any metabolites associated with red meat intake are also associated with inflammation.

METHODS: A cross-sectional analysis of observational data from older adults (52.84% women, mean age 63 ± 0.3 y) participating in the Multi-Ethnic Study of Atherosclerosis (MESA). Dietary intake was assessed by food-frequency questionnaire, alongside C-reactive protein (CRP), interleukin-2, interleukin-6, fibrinogen, …

Site-Specific Pathophysiology In A Neonatal Mouse Model Of Gastroparesis, Price T Edwards, Krishnakant G Soni, Margaret E Conner, Stephanie W Fowler, Jaime P P Foong, Rhian Stavely, Lily S Cheng, Geoffrey A Preidis

Faculty, Staff and Students Publications

BACKGROUND: Early-life events impact maturation of the gut microbiome, enteric nervous system, and gastrointestinal motility. We examined three regions of gastric tissue to determine how maternal separation and gut microbes influence the structure and motor function of specific regions of the neonatal mouse stomach.

METHODS: Germ-free and conventionally housed C57BL/6J mouse pups underwent timed maternal separation (TmSep) or nursed uninterrupted (controls) until 14 days of life. We assessed gastric emptying by quantifying the progression of gavaged fluorescein isothiocyanate (FITC)-dextran. With isolated rings of forestomach, corpus, and antrum, we measured tone and contractility by force transduction, gastric wall thickness by light …

Breastfeeding And Risk Of Childhood Brain Tumors: A Report From The Childhood Cancer And Leukemia International Consortium, Jeremy M Schraw, Eleni Th Petridou, Audrey Bonaventure, John D Dockerty, Maria Karalexi, Evangelia Ntzani, Claire Infante-Rivard, Jacqueline Clavel, Paige M Bracci, Roberta Mckean-Cowdin, Eve Roman, Eleanor Kane, Friederike Erdmann, Joachim Schüz, Beth A Mueller, Michael E Scheurer

Faculty, Staff and Students Publications

Purpose: Studies report mixed findings regarding the association of breastfeeding with childhood brain tumors (CBT), the leading causes of cancer-related mortality in young people. Our objective was to determine whether breastfeeding is associated with CBT incidence.

Methods: We pooled data on N = 2610 cases with CBT (including 697 cases with astrocytoma, 447 cases with medulloblastoma/primitive neuroectodermal tumor [PNET], 167 cases with ependymoma) and N = 8128 age- and sex-matched controls in the Childhood Cancer and Leukemia International Consortium. We computed unconditional logistic regression models to estimate the odds ratio (OR) and 95% confidence interval (CI) of CBT, astrocytoma, medulloblastoma/PNET, …

The Health Effects Of Climate Change: Experiences Of Young People In Bangladesh, Guatemala, And Nigeria, Population Council, Women Deliver

Adolescents and Young People

Climate change is affecting the health and well-being of adolescents and young people (AYP) worldwide. This happens through direct exposure pathways but mainly indirectly, by influencing economic and food insecurity, access to health services, and harmful gender norms and social inequalities. According to a recent meta-analysis of 130 studies, climate change disproportionately harms the health of women and girls, especially younger generations. There are intergenerational inequities in exposure to climate extremes. A child born in 2020 will face an up to sevenfold increase in extreme climate events compared to one born in 1960. These events will have cascading harms and …

Corrigendum To 'Pressure-Mediated Reflection Spectroscopy Criterion Validity As A Biomarker Of Fruit And Vegetable Intake: A 2-Site Cross-Sectional Study Of 4 Racial Or Ethnic Groups' [J Nutr 2022;152:107-116], Stephanie B Jilcott Pitts, Nancy E Moran, Qiang Wu, Lisa Harnack, Neal E Craft, Neil Hanchard, Ronny Bell, Stacey G Moe, Nevin Johnson, Justice Obasohan, Pamela L Carr-Manthe, Melissa N Laska

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Examining Potential Modifiers Of Human Skin And Plasma Carotenoid Responses In A Randomized Trial Of A Carotenoid-Containing Juice Intervention, Stephanie B Jilcott Pitts, Qiang Wu, Nancy E Moran, Melissa N Laska, Lisa Harnack

Children’s Nutrition Research Center Staff Publications

Background: Skin carotenoid measurements are emerging as a valid and reliable indicator of fruit and vegetable intake and carotenoid intake. However, little is known about the extent to which skin carotenoid responsivity to dietary changes differs based on demographic and physiologic characteristics.

Objectives: This study examined potential effect modifiers of skin carotenoid and plasma carotenoid responses to a carotenoid-rich juice intervention.

Methods: We leveraged data from 2 arms of a 3-site randomized controlled trial of a carotenoid-containing juice intervention (moderate dose = 6 ounces juice, 4 mg total carotenoids/d, high dose = 12 ounces juice, 8 mg total carotenoids/d) (n …

N Y State Dent J November 2023

The New York State Dental Journal

In the November 2023 issue, the reader will find the following feature articles:

• Verruciform Xanthoma
• Use of a 3D Intraoral Scanner for Prosthetic Rehabilitation of Cocaine-Induced Oronasal Fistula
• Adenoid Ameloblastoma with Dentinoid

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Towards Llm-Based Fact Verification On News Claims With A Hierarchical Step-By-Step Prompting Method, Xuan Zhang, Wei Gao

Research Collection School Of Computing and Information Systems

While large pre-trained language models (LLMs) have shown their impressive capabilities in various NLP tasks, they are still underexplored in the misinformation domain. In this paper, we examine LLMs with in-context learning (ICL) for news claim verification, and find that only with 4-shot demonstration examples, the performance of several prompting methods can be comparable with previous supervised models. To further boost performance, we introduce a Hierarchical Step-by-Step (HiSS) prompting method which directs LLMs to separate a claim into several subclaims and then verify each of them via multiple questionsanswering steps progressively. Experiment results on two public misinformation datasets show that …

The Association Between Attachment Styles And Binge Eating Behaviours: Examination Of The Mediational Role Of Emotional Dysregulation In The Arab Region, Diala Kassab

Theses

Many factors are said to affect binge eating behaviours, one of these factors is the individual’s attachment style. Attachment styles is the early relationship that shape a child's ideas and expectations about themselves and the availability of other people. This can be mediated by the ability to effectively respond and manage emotional experiences. This thesis aimed to examine the role of emotional dysregulation on attachments styles and binge eating behaviours in the Arab region.
/="/">A sample of 326 Arab university students, predominantly Emirati and Lebanese, were recruited using convenience sampling and snowball sampling technique. Participants were asked to complete …

The Relationship Between Startups’ Early Adoption Of Digital Platforms And Startups’ Pre-Money Valuation, Bader Hassan Faqeeh

Dissertations

The objective of this study was to explore whether there was a significant positive relationship between startups’ early adoption of the digital platforms, namely, 1) mobile application, 2) a premium domain name website, and 3) the existence of active startup social media accounts, and startups’ pre-money valuation. To achieve this objective, this research used a relatively novel method in entrepreneurial research to collect data, whereby LinkedIn’s Sales Navigator was used along with an automation tool in order to send hundreds of automated connection and message requests to investors on LinkedIn who were sent a copy of the survey questions along …

Innovative Approaches To Poultry Processing Wastewater Treatment: The Stainless Steel Ultrafiltration Membrane As A Viable Option, Saubana Olorunrola Dada, Chidambaram Thamariselvan, Mahmood Jebur, Sumith Ranil Wickramasinghe

Chemical Engineering Faculty Publications and Presentations

In pursuit of sustainability, we explored replacing conventional dissolved air floatation (DAF) in poultry processing wastewater (PPW) treatment with a precisely tuned 0.02 µm stainless-steel ultrafiltration (SSUF) membrane. SSUF is a robust, homogenously porous membrane with strong chemical resistance, ease of cleaning, and exceptional resistance to organic fouling. Unlike polymeric membranes, it can be regenerated multiple times, making it a cost-effective choice due to its compatibility with harsh chemical cleaning. The PPW used for the study was untreated wastewater from all processing units and post-initial screening. Our study revealed the SSUF membrane’s exceptional efficiency at eliminating contaminants. It achieved an …

Behavioral Science Interventions Could Increase Snap Comprehension And Awareness Among Military Families, Colleen Heflin, Hannah Patnaik, Leonard M. Lopoo, Siobhan O'Keefe

Center for Policy Research

Food insecurity is more common among military families than the general population, and the transition from active service to civilian life is a time of heightened risk. The Supplemental Nutritional Assistance Program (SNAP) is designed to support food security among low-income families. Many eligible military and veteran families do not enroll in SNAP due to a lack of information, stigma, and administrative barriers. This brief highlights findings from a survey experiment conducted in 2022 and 2023 to assess how small changes to SNAP informational flyers, such as simplifying information provided about SNAP, highlighting that other veterans use SNAP, and emphasizing …

Genome-Wide Interaction Analysis Of Folate For Colorectal Cancer Risk, Emmanouil Bouras, Andre E Kim, Yi Lin, John Morrison, Mengmeng Du, Demetrius Albanes, Elizabeth L Barry, James W Baurley, Sonja I Berndt, Stephanie A Bien, Timothy D Bishop, Hermann Brenner, Arif Budiarto, Andrea Burnett-Hartman, Peter T Campbell, Robert Carreras-Torres, Graham Casey, Tjeng Wawan Cenggoro, Andrew T Chan, Jenny Chang-Claude, David V Conti, Michelle Cotterchio, Matthew Devall, Virginia Diez-Obrero, Niki Dimou, David A Drew, Jane C Figueiredo, Graham G Giles, Stephen B Gruber, Marc J Gunter, Tabitha A Harrison, Akihisa Hidaka, Michael Hoffmeister, Jeroen R Huyghe, Amit D Joshi, Eric S Kawaguchi, Temitope O Keku, Anshul Kundaje, Loic Le Marchand, Juan Pablo Lewinger, Li Li, Brigid M Lynch, Bharuno Mahesworo, Satu Männistö, Victor Moreno, Neil Murphy, Polly A Newcomb, Mireia Obón-Santacana, Jennifer Ose, Julie R Palmer, Nikos Papadimitriou, Bens Pardamean, Andrew J Pellatt, Anita R Peoples, Elizabeth A Platz, John D Potter, Lihong Qi, Conghui Qu, Gad Rennert, Edward Ruiz-Narvaez, Lori C Sakoda, Stephanie L Schmit, Anna Shcherbina, Mariana C Stern, Yu-Ru Su, Catherine M Tangen, Duncan C Thomas, Yu Tian, Caroline Y Um, Franzel Jb Van Duijnhoven, Bethany Van Guelpen, Kala Visvanathan, Jun Wang, Emily White, Alicja Wolk, Michael O Woods, Cornelia M Ulrich, Li Hsu, W James Gauderman, Ulrike Peters, Konstantinos K Tsilidis

Faculty, Staff and Student Publications

Background: Epidemiological and experimental evidence suggests that higher folate intake is associated with decreased colorectal cancer (CRC) risk; however, the mechanisms underlying this relationship are not fully understood. Genetic variation that may have a direct or indirect impact on folate metabolism can provide insights into folate's role in CRC.

Objectives: Our aim was to perform a genome-wide interaction analysis to identify genetic variants that may modify the association of folate on CRC risk.

Methods: We applied traditional case-control logistic regression, joint 3-degree of freedom, and a 2-step weighted hypothesis approach to test the interactions of common variants (allele frequency >1%) …

Burden Of Respiratory Failure In Pediatric Patients: Analysis Of A Prospective Multicenter Cohort In Bogotá, Colombia, Laura Hernández-Corredor, Rocio Plazas-Pachón, Fernanda Argote-Bolaños, Pedro Barrera-Lopez, Melisa Naranjo Vanegas, Sergio Moreno-Lopez, Paola Rueda-Guevara, Juan G Piñeros, Olga Lucía Baquero Castañeda, Carolina Bonilla, Luz M Mejía, María L Mesa, Sonia Restrepo-Gualteros, Andrea Ramírez Varela

Faculty, Staff and Student Publications

BACKGROUND AND AIMS: The approach to the burden of disease is a demographic, economic, and a health problem, which requires the design and application of specific measures of cost of the disease, such as disability-adjusted life years (DALYs), to establish better public health policies in the pediatric population. The aim of this study is to approach the burden of disease in children with acute respiratory failure (ARF) through the calculation of DALYs.

METHODS: This study was conducted in the framework of a prospective, multicenter cohort in Bogotá, Colombia. Inclusion criteria were all pediatric patients admitted to the emergency department, hospitalization, …

November 2023, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Eat Right, Every Bite

An Apple a Day …

Staff and faculty MASSAGES

Five Tips for Exercising Safely in Cold Weather

Community Water Fluoridation In Focus: A Comprehensive Look At Fluoridation Levels Across America, Man Hung, Amir Mohajeri, Jody Chiang, Jungweon Park, Beatrice Bautista, Chase Hardy, Martin S. Lipsky

Institute on Aging Publications

Objective: This study reports on the number and percentage of community water systems (CWSs) meeting fluoride concentration standards set by the U.S. Department of Health and Human Services (DHHS). The study also explored changes in the population exposed to optimally fluoridated water in these systems between 2006 and 2020. Methods: This study analyzed U.S. Centers for Disease Control and Prevention data from 2006 to 2020, tabulating state-specific CWS fluoridation rates, ranking them, and calculating the percent change. Results: In 2020, 72.7% of the US population received CWS water, with 62.9% of those individuals served by a CWS system meeting DHHS …

The Alternative Livestock Revolution: Prospects For Consumer Acceptance Of Plant-Based And Cultured Meat In South Africa, Chiedza Tsvakirai, Lawton Nalley, Shelby Rider, Ellen Van Loo, Makgopa Tshehla

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Although South Africa accounts for half of the alternative meat market for the African continent, there remains a lack of information about consumer demand for plant-based and lab-cultured meat and its market potential domestically. This study reports the results of a nationwide survey of 649 South African consumers who completed a choice experiment in which they selected among conventional beef and three alternative burger patties at varying prices. Results indicate that holding prices constant and conditional on choosing a food product, 21% of the market share was estimated for plant-based meat alternatives and 38% for lab-cultured meat.

Blood-Based Migration Signature Biomarker Panel Discriminates Early Stage New Onset Diabetes Related Pancreatic Ductal Adenocarcinoma From Type 2 Diabetes, Seetharaman Balasenthil, Suyu Liu, Jianliang Dai, William R Bamlet, Gloria Petersen, Suresh T Chari, Anirban Maitra, Nanyue Chen, Subrata Sen, Ann Mcneill Killary

Faculty, Staff and Student Publications

Background and aims: While type 2 diabetes is a well-known risk factor for pancreatic ductal adenocarcinoma (PDAC), PDAC-induced new-onset diabetes (PDAC-NOD) is a manifestation of underlying PDAC. In this study, we sought to identify potential blood-based biomarkers for distinguishing PDAC-NOD from type 2 diabetes (T2DM) without PDAC.

Materials and methods: By ELISA analysis, a migration signature biomarker panel comprising tissue factor pathway inhibitor (TFPI), tenascin C (TNC-FNIII-C) and CA 19-9 was analyzed in plasma samples from 50 PDAC-NOD and 50 T2DM controls.

Results: Both TFPI (area under the curve (AUC) 0.71) and TNC-FNIII-C (AUC 0.69) outperformed CA 19-9 (AUC 0.60) …