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Articles 10981 - 10990 of 10990
Full-Text Articles in Entire DC Network
Recommendations From Diabetes Uk's 2022 Diabetes And Physical Activity Workshop, Anna Morris, Chris Bright, Matthew Cocks, Neil Gibson, Louise Goff, Colin Greaves, Simon Griffin, Ben Jane, Florence Kinnafick, Paul Robb, Michelle Roberts, David Salman, John Saxton, Adrian Taylor, Daniel West, Thomas Yates, Rob C. Andrews, Jason M.R. Gill
Recommendations From Diabetes Uk's 2022 Diabetes And Physical Activity Workshop, Anna Morris, Chris Bright, Matthew Cocks, Neil Gibson, Louise Goff, Colin Greaves, Simon Griffin, Ben Jane, Florence Kinnafick, Paul Robb, Michelle Roberts, David Salman, John Saxton, Adrian Taylor, Daniel West, Thomas Yates, Rob C. Andrews, Jason M.R. Gill
Peninsula Medical School
Abstract Aims To describe the process and outputs of a workshop convened to identify key priorities for future research in the area of diabetes and physical activity and provide recommendations to researchers and research funders on how best to address them. Methods A 1‐day research workshop was conducted, bringing together researchers, people living with diabetes, healthcare professionals, and members of staff from Diabetes UK to identify and prioritise recommendations for future research into physical activity and diabetes. Results Workshop attendees prioritised four key themes for further research: (i) better understanding of the physiology of exercise in all groups of people: …
Survey Of Parents Of Children With Intellectual Disabilities And/Or Autism Who Experience Chronic Constipation, James Rooney, Rebecca Hodge, Jade Smith, Kelly Vanstone, Richard Laugharne, Rohit Shankar
Survey Of Parents Of Children With Intellectual Disabilities And/Or Autism Who Experience Chronic Constipation, James Rooney, Rebecca Hodge, Jade Smith, Kelly Vanstone, Richard Laugharne, Rohit Shankar
Peninsula Medical School
Background: Constipation is common in children with intellectual disabilities and/or autism, but poorly researched. This study looks to understand parental knowledge, attitudes and management practices towards constipation in children with intellectual disabilities and/or autism. Methods: A cross-sectional online survey developed with patient facing organisations was circulated to parents of children with intellectual disabilities and/or autism using an exponential and non-discriminatory snowballing method for recruitment. A smaller sample were purposively sampled for their in-depth experiences. Results: Of 68 responses, people were open to discussing constipation and knowledgeable about risk factors. In the qualitative interviews, of 15 parents, they wanted to be …
Abnormal Thalamic Functional Connectivity Correlates With Cardiorespiratory Fitness And Physical Activity In Progressive Multiple Sclerosis, Francesco Romanò, Robert W. Motl, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolò Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Maria A. Rocca, Massimo Filippi
Abnormal Thalamic Functional Connectivity Correlates With Cardiorespiratory Fitness And Physical Activity In Progressive Multiple Sclerosis, Francesco Romanò, Robert W. Motl, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolò Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Maria A. Rocca, Massimo Filippi
School of Health Professions
BackgroundAltered thalamic volumes and resting state (RS) functional connectivity (FC) might be associated with physical activity (PA) and cardiorespiratory fitness (CRF) in people with progressive multiple sclerosis (PMS).ObjectivesTo assess thalamic structural and functional alterations and investigate their correlations with PA/CRF levels in people with PMS.MethodsSeven-day accelerometry and cardiopulmonary exercise testing were used to assess PA/CRF levels in 91 persons with PMS. They underwent 3.0 T structural and RS fMRI acquisition with 37 age/sex-matched healthy controls (HC). Between-group comparisons of MRI measures and their correlations with PA/CRF variables were assessed.ResultsPMS people had lower volumes compared to HC (all p < 0.001). At corrected threshold, PMS showed decreased intra- and inter-thalamic RS FC, and increased RS FC between the thalamus and the hippocampus, bilaterally. At uncorrected threshold, decreased thalamic RS FC with caudate nucleus, cerebellum and anterior cingulate cortex (ACC), as well as increased thalamic RS FC with occipital regions, were also detected. Lower CRF, measured as peak oxygen consumption (VO2peak), correlated with lower white matter volume (r = 0.31, p = 0.03). Moreover, lower levels of light PA correlated with increased thalamic RS FC with the right hippocampus (r = − 0.3, p = 0.05).DiscussionPeople with PMS showed widespread brain atrophy, as well as pronounced intra-thalamic and thalamo-hippocampal RS FC abnormalities. White matter atrophy correlated with CRF, while increased thalamo-hippocampal RS FC was associated to worse PA levels. Thalamic RS FC might be used to monitor physical impairment and efficacy of rehabilitative and disease-modifying treatments in future studies.
Cognitive Rehabilitation And Aerobic Exercise For Cognitive Impairment In People With Progressive Multiple Sclerosis (Cogex): A Randomised, Blinded, Sham-Controlled Trial, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Alex Pietrusz, Andrea Tacchino, A Smith, Anne Sophie Michelsen, Ashlie Kristin, Blake Bichler, Brendon Truax, Carmen Vizzino, Catherine Danielle Jones, Catherine Holme, C Smith, Charly Keytsman, Chiara Pollio, Chris Cole, Claudia Niccolai, Claudio Cordani, Eleonora Colombo, Elisa Pelosin, Ellen Vanzeir, Fedrica Vannetti, Filippo Gerli, Francesco Maranta, Gianna Riccitelli, Guido Pasquini, Holly Wilkinson, Irene Mosca, James Braisher, Jessica Baird, Jessica Podda, Jimmy Morecraft, Joke Lenaerts, Juliana Puopolo, K Algie, L Kenton, L Toll, Lt Madsen, L Knevels, L Lee, L Pedullà, M Cellerino, James Braisher, M-Lk Jørgensen, M Pardini, M Sibilia, M Nabarro, Md Diedmann, M Dibenedetto, M Curran, M Koch, M D'Hooge, N Moore, Nd Weerdt, P Preziosa, P Pajak, P Silic, Rb Walters, R Finegan, R Veldkamp, R Hernandez, R Donnee, S Casagrande, S Lancia, Sd Bella, S Vandecasteele, V Vandael
Cognitive Rehabilitation And Aerobic Exercise For Cognitive Impairment In People With Progressive Multiple Sclerosis (Cogex): A Randomised, Blinded, Sham-Controlled Trial, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Alex Pietrusz, Andrea Tacchino, A Smith, Anne Sophie Michelsen, Ashlie Kristin, Blake Bichler, Brendon Truax, Carmen Vizzino, Catherine Danielle Jones, Catherine Holme, C Smith, Charly Keytsman, Chiara Pollio, Chris Cole, Claudia Niccolai, Claudio Cordani, Eleonora Colombo, Elisa Pelosin, Ellen Vanzeir, Fedrica Vannetti, Filippo Gerli, Francesco Maranta, Gianna Riccitelli, Guido Pasquini, Holly Wilkinson, Irene Mosca, James Braisher, Jessica Baird, Jessica Podda, Jimmy Morecraft, Joke Lenaerts, Juliana Puopolo, K Algie, L Kenton, L Toll, Lt Madsen, L Knevels, L Lee, L Pedullà, M Cellerino, James Braisher, M-Lk Jørgensen, M Pardini, M Sibilia, M Nabarro, Md Diedmann, M Dibenedetto, M Curran, M Koch, M D'Hooge, N Moore, Nd Weerdt, P Preziosa, P Pajak, P Silic, Rb Walters, R Finegan, R Veldkamp, R Hernandez, R Donnee, S Casagrande, S Lancia, Sd Bella, S Vandecasteele, V Vandael
School of Health Professions
Background Cognitive dysfunction in people with relapsing-remitting multiple sclerosis can improve with cognitive rehabilitation or exercise. Similar effects have not been clearly shown in people with progressive multiple sclerosis. We aimed to investigate the individual and synergistic effects of cognitive rehabilitation and exercise in patients with progressive multiple sclerosis. Methods CogEx was a randomised, sham-controlled trial completed in 11 hospital clinics, universities, and rehabilitation centres in Belgium, Canada, Denmark, Italy, UK, and USA. Patients with progressive multiple sclerosis were eligible for inclusion if they were aged 25–65 years and had an Expanded Disability Status Scale (EDSS) score of less than …
Differential Response And The Reduction Of Child Maltreatment And Foster Care Services Utilization In The U.S. From 2004 To 2017, Michelle Johnson-Motoyama, Donna K. Ginther, Rebecca Phillips, Oliver W.J. Beer, Lisa Merkel-Holguin, John Fluke
Differential Response And The Reduction Of Child Maltreatment And Foster Care Services Utilization In The U.S. From 2004 To 2017, Michelle Johnson-Motoyama, Donna K. Ginther, Rebecca Phillips, Oliver W.J. Beer, Lisa Merkel-Holguin, John Fluke
School of Health Professions
By 2014, the majority of U.S. states had implemented differential response (DR), a system policy that seeks to serve families of low-to moderate-risk for child maltreatment through family engagement, diversion from formal child protective services investigations, and service provision. However, the effects of DR programs on child welfare dynamics have yet to be evaluated nationally using causal methods. Using a quasi-experimental study design with data drawn from the National Child Abuse and Neglect Data System from 2004 to 2017, we found states with DR programs had approximately 19% fewer substantiated reports, 25% fewer children substantiated for neglect, and a 17% …
A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson
A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson
School of Nursing and Midwifery
No abstract provided.
Embedding Health And Wellbeing Opportunities For People Experiencing Homelessness In A Wider Support System, M. Paisi, L. Withers, J. Erwin, J. Horrell, R. Witton, J. Shawe, R. Byng
Embedding Health And Wellbeing Opportunities For People Experiencing Homelessness In A Wider Support System, M. Paisi, L. Withers, J. Erwin, J. Horrell, R. Witton, J. Shawe, R. Byng
School of Nursing and Midwifery
IntroductionHomelessness impacts negatively on health, wellbeing and life expectancy. People experiencing homelessness are likely to suffer physical and mental health problems, be heavy users of emergency services, and die 30 years earlier than the general population.1–3 Their severe and multiple disadvantages raise personal and institutional barriers to using health, social and housing services.4In late 2021, a grass-roots initiative in Plymouth began offering a Saturday morning drop-in service for rough sleepers and those in emergency accommodation. The service responded to the bleakness, loneliness and lack of support imposed by Monday-Friday service patterns. This effort was strengthened in February 2022 by a …
Student-Led Health Promotion Toolkit: A Practice Development Project, R Reynolds, S Neill
Student-Led Health Promotion Toolkit: A Practice Development Project, R Reynolds, S Neill
School of Nursing and Midwifery
Student nurses are uniquely placed to contribute to health promotion during their undergraduate programmes. The aim of this practice development project was to co-develop a toolkit to facilitate student nurse led health promotion practice. The project used an emancipatory methodology to explore health promotion practice opportunities for one university cohort of student nurses in partnership with the local practice area. A person-centred framework was used to engage with students and nurses to benchmark current student practice, scope for student-led activity and develop a shared vision for the toolkit resources. The student questionnaire revealed greater confidence in health promotion knowledge than …
End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers
End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers
School of Nursing and Midwifery
This study aims to describe end-of-life (EOL) care in older patients with cancer and investigate the association between geriatric assessment (GA) results and specialized palliative care (SPC) use. Older patients with a new cancer diagnosis (2009–2015) originally included in a previous multicentric study were selected if they died before the end of follow-up (2019). At the time of cancer diagnosis, patients underwent geriatric screening with Geriatric 8 (G8) followed by GA in case of a G8 score ≤14/17. These data were linked to the cancer registry and healthcare reimbursement data for follow-up. EOL care was assessed in the last three …
Major Biochemical Constituents Of Withania Somnifera (Ashwagandha) Extract: A Review Of Chemical Analysis, Ekram Hany Mohamed, Mahmoud Tareq Abdelwahed,, Maha A. Hegazy
Major Biochemical Constituents Of Withania Somnifera (Ashwagandha) Extract: A Review Of Chemical Analysis, Ekram Hany Mohamed, Mahmoud Tareq Abdelwahed,, Maha A. Hegazy
Pharmacy
Ashwagandha (Withania somnifera) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antioxidant, adaptogen, memory enhancer, and possess an effect on neurodegenerative diseases. Additionally, it was revealed that the plant exerts antibacterial, antiviral, antitumor, aphrodisiac, and cardiovascular protection activities. Due to the biological and nutritional importance of nutraceuticals, particularly ashwagandha, and as part of the ongoing research of the natural products and its bioactive phytochemicals, this review aims …