Digital Commons Network^™

The Gastrointestinal-Brain-Microbiota Axis: A Promising Therapeutic Target For Ischemic Stroke, Yan-Hao Wei, Ren-Tang Bi, Yan-Mei Qiu, Chun-Lin Zhang, Jian-Zhuang Li, Ya-Nan Li, Bo Hu

Faculty, Staff and Student Publications

Ischemic stroke is a highly complex systemic disease characterized by intricate interactions between the brain and gastrointestinal tract. While our current understanding of these interactions primarily stems from experimental models, their relevance to human stroke outcomes is of considerable interest. After stroke, bidirectional communication between the brain and gastrointestinal tract initiates changes in the gastrointestinal microenvironment. These changes involve the activation of gastrointestinal immunity, disruption of the gastrointestinal barrier, and alterations in gastrointestinal microbiota. Importantly, experimental evidence suggests that these alterations facilitate the migration of gastrointestinal immune cells and cytokines across the damaged blood-brain barrier, ultimately infiltrating the ischemic brain. …

Coronary Heart Disease And Ischemic Stroke Polygenic Risk Scores And Atherosclerotic Cardiovascular Disease In A Diverse, Population-Based Cohort Study, Allison Bebo, Jamie A Jarmul, Mark J Pletcher, Natalie R Hasbani, David Couper, Vijay Nambi, Christie M Ballantyne, Myriam Fornage, Alanna C Morrison, Christy L Avery, Paul S De Vries

Faculty, Staff and Student Publications

The predictive ability of coronary heart disease (CHD) and ischemic stroke (IS) polygenic risk scores (PRS) have been evaluated individually, but whether they predict the combined outcome of atherosclerotic cardiovascular disease (ASCVD) remains insufficiently researched. It is also unclear whether associations of the CHD and IS PRS with ASCVD are independent of subclinical atherosclerosis measures. 7,286 White and 2,016 Black participants from the population-based Atherosclerosis Risk in Communities study who were free of cardiovascular disease and type 2 diabetes at baseline were included. We computed previously validated CHD and IS PRS consisting of 1,745,179 and 3,225,583 genetic variants, respectively. Cox …

Addressing Training Gaps: A Competency-Based, Telehealth Training Initiative For Community Health Workers, Laura Porterfield, Victoria Warren, Vanessa Schick, Shannon Gulliot-Wright, Jeff R Temple, Elizabeth M Vaughan

Faculty, Staff and Student Publications

BACKGROUND: To overcome vast variations in Community Health Worker (CHW) training, investigators for the CHW Core Consensus Project (CCCP) derived three types of CHW (Category 1, 2, 3) and established competencies for each category. However, studies are needed that implement these competencies in real-world settings.

OBJECTIVE: Using the six competency domains of the CCCP as a theoretical backbone, we developed and evaluated a training for

METHODS: We developed five telehealth-based, bilingual (Spanish/English) training sessions and implemented them among

RESULTS: All (18/18) CHWs achieved at least 70% on the posttest (mean: 93.7%; range 73.3-100%). Training attendance was 98.9%. Using a six-point …

Csq Portland/Seattle Contributors Index

INDEX of Portland/Seattle Contributors

No abstract provided.

Human Rights, Human Duties: Making A Rights-Based Case For Community-Based Restorative Justice,, Aparna Polavarapu

Scholarly Works

Restorative justice is often framed as an alternative to the criminal legal system, and thus justifications of restorative justice tend to be rooted in the language of the criminal system. However, this approach limits our way of thinking about the practice of restorative justice, especially non-state, community-based practices. This Article argues for an independent, rights-based justification to support these community-based practices. By offering an in-depth analysis originating from a rights-based perspective, this Article engages with two underdeveloped areas of scholarly literature and suggests a new way of thinking about the day-to-day practice of restorative justice through a human rights lens. …

Cyclic Di Amp Level In Various Mutants And Clinical Isolates Of Streptococcus Pyogenes, Tasmim Hossain

All-Inclusive List of Electronic Theses and Dissertations

Streptococcus pyogenes is a Gram-positive aerotolerant bacterium that is an extracellular, non-motile, non-sporulating pathogen. They are clinically important in humans not only because of their pathogenicity but their remarkable ability to adapt to harsh conditions. Viability and virulence of S. pyogenes are reported to be associated with cyclic-di-adenosine monophosphate (c-di-AMP). Proper biosynthesis of this second messenger is essential to maintain ionic balance, homeostasis and cell envelope integrity as it has been reported to be associated with the expression of the virulence factors SpeB which the pathogens use to fight the host immune system leading to infection development. c-di-AMP helps S. …

Implications With Identifying Gifted Black Students: A Study Of Implicit Bias, Christen H. Diehl

All-Inclusive List of Electronic Theses and Dissertations

The purpose of this quantitative study was to examine if implicit bias among Indiana educators might affect the identification of gifted Black students for programming. Educators, within school districts with high minority populations, were asked to provide a demographic survey and then take the Implicit Association Test (IAT). Survey data were then collected to determine if potential demographic information like gender, race, the possession of a high ability license, years of experience, highest collegiate degree, or their professional role had a statistical significance when compared to their IAT score. Using t-tests and one-way ANOVAs, demographic data were able to be …

Exploring The Benefits Of Library Consortium: The Information Resource Sharing., Muhammad Bala Kasim, Fati Abba, Hajara Jibril, Yahaya Abdullahi Isah, Aliyu Muhammad Babadoko

Library Philosophy and Practice (e-journal)

This paper examines the cardinal benefits of library consortium which is the resource sharing. Resource sharing aims at maximizing collection and services of libraries and information centres at minimum cost. Various sources of information (primary and secondary literature) were perused to view the essentiality of resource sharing in carrying out effective and efficient library and information services to users. The paper also highlighted the requirements needed for successful resource sharing practices among libraries. The significance/benefits of resource sharing as it relates to economic, developmental, academic/research as well as social life of librarians and library personnel were clearly stated. An ideal …

Protocol Of Detection Of West Nile Virus In Clinical Samples, Hephzibah Nwanosike, Freedom M Green, Kristy O Murray, Jill E Weatherhead, Shannon E Ronca

Faculty, Staff and Students Publications

West Nile virus (WNV) is one of the leading causes of arboviral encephalitis in the United States but is often underdiagnosed. Despite the wide breadth of WNV-induced clinical disease syndromes, many of the symptoms associated with WNV are nonspecific at the time of presentation; thus, choosing the right diagnostic tool is essential to not only understand the true burden of disease but also provide pathogen-directed interventions for WNV-infected patients. In this chapter, we briefly discuss the three most common types of diagnostic methods for WNV in human clinical samples: nucleic acid detection, enzyme-linked immunoassay (ELISA), and plaque reduction neutralization test …

Safety Procedures To Work With West Nile Virus In Biosafety Level 3 Facilities, Freedom M Green, Shannon E Ronca

Faculty, Staff and Students Publications

West Nile virus (WNV) can cause severe and sometimes fatal disease, but we do not have treatments or therapeutics to manage these outcomes. Since its introduction to the USA in 1999, WNV has been handled in a biosafety level 3 laboratory to decrease risk to researchers, requiring strict safety protocols and important considerations with planning experiments. Recent changes in US guidelines suggest that WNV can be handled at a lower biosafety level due to its endemicity in the USA and generally minor symptoms, but some research still requires the use of the agent at biosafety level 3. This chapter will …

Aesthetic Choices: Defining The Range Of Aesthetic Views In Interactive Digital Media Including Games And 3d Virtual Environments (3d Ves), Hira Maqbool

Theses: Doctorates and Masters

Defining aesthetic choices for interactive digital media such as games is a challenging task. Objective and subjective factors such as colour, symmetry, order and complexity, and statistical features among others play an important role for defining the aesthetic properties of interactive digital artifacts. Computational approaches developed in this regard also consider objective factors such as statistical image features for the assessment of aesthetic qualities. However, aesthetics for interactive digital media, such as games, requires more nuanced consideration than simple objective and subjective factors, for choosing a range of aesthetic features.

From the study it was found that the there is …

Plant-Herbivore Interactions In A Changing Climate And Implications For Seagrass Resilience, Caitlyn M. O'Dea

Theses: Doctorates and Masters

Climate change is affecting herbivore distributions and abundance, resulting in intensified grazing pressure on foundation species such as seagrasses. This, coupled with other, rapid changes in estuarine ecosystems, may threaten the resilience of seagrass. While the overall resilience of seagrasses is generally well-studied, the timeframes of recovery have received comparatively little attention, particularly in temperate estuaries. This study investigated the recovery time of two colonising seagrasses (Halophila ovalis and Ruppia megacarpa) following various intensities of simulated grazing in two southwestern Australian estuaries. Simulated grazing treatments (25%, 50%, 75%, and 100% removal from 1 m2 plots) were applied in field experiments …

The Concept And Role Of Meaningful Work In The Context Of Pakistan – An Exploratory Study Of Junior Doctors, Abid Hussain

Theses: Doctorates and Masters

Over the past decade, the concept of meaningful work has gained increased attention from human resource management, organisational science, and management scholars. This can be largely attributed to the growing global concern for the wellbeing and meaningful engagement of individuals in the workforce, especially since the COVID-19 pandemic. The literature on meaningful work reveals that there are multiple perspectives and theoretical approaches to the conceptualisation of meaningful work which can be found primarily within Western societies and Western scholarship and are often based on Western worldviews. Most of the quantitative and qualitative empirical studies adopt a reductionist approach and tend …

Carbon Geosequestration And Enhanced Oil Recovery In Geological Formations: Multi-Scale Analysis, Auby Baban

Theses: Doctorates and Masters

Carbon geosequestration (CGS) has been recognized as a strategic solution to prevent/counter the catastrophic consequences of climate change. However, despite recent cutting-edge technical research, predicting quantitative CO2 trapping in geological formations via capillary trapping is currently scarce. Moreover, several aspects of multiphase flow characteristics of CO2/brine/rock systems, that greatly impact carbon capture and containment security, require further investigations. Furthermore, combining carbon geosequestration with Enhanced Oil Recovery (EOR) is an efficient and economically attractive technology to reduce global warming caused by emissions of anthropologic CO2 from the combustion of fossil fuels, whereby it offsets some of the costs of CO2 extraction. …

Food Standards Agency, London (2023) Estimating Financial Cost To Individuals With A Food Hypersensitivity Project Report., Ciara Walsh

Research Outputs: 2025-Present

The Food Standards Agency (FSA) is a non-ministerial government department within the United Kingdom responsible for protecting public health and protecting consumer interests in relation to food in England, Wales, and Northern Ireland. Food Hypersensitivities (FHS) is a key priority within the FSA as it is an important food-related health issue with a severe and enduring impact for people living with it. FHS includes individuals living with a food allergy, coeliac disease and food intolerance.It is the responsibility of the FSA to seek ways to understand and reduce avoidable deaths, the negative impact of FHS on both consumers and businesses, …

Adolescent Overweight And Obesity In Ireland—Trends And Sociodemographic Associations Between 1990 And 2020, Aoibhín Moore Heslin, Aisling O'Donnell, Laura Kehoe, Janette Walton, Albert Flynn, John Kearney, Breige Mcnulty

Articles

Background: Overweight and obesity in adolescence is a growing issue and can have a range of both short- and long-term consequences on health.

Objectives: To analyse trends in adolescent weight status in Ireland across a 30-year period and to examine the influence of sociodemographic factors on overweight/obesity in Irish adolescents over time.

Methods: Body composition and body mass index weight status of Irish adolescents were compared using data from three nationally representative, cross-sectional Irish national food consumption surveys from 1990, 2006 and 2020. Adjusted analysis of associations between socio-demographic factors with the risk of adolescent overweight/obesity at each time point …

Synthesis, Characterisation, And Solution Behaviour Of Ag(I) Bis(Phenanthroline‑Oxazine) Complexes And The Evaluation Of Their Biological Activity Against The Pathogenic Yeast Candida Albicans, Clara Evans, Muhib Ahmed, Malachy Mccann, Kevin Kavanagh, Michael Devereux, Denise Rooney Denise Rooney, Frances Heaney

Articles

Three Ag(I) bis(phenanthroline-oxazine) complexes with varying lipophilicity were synthesised and characterised. The solution stoichiometry of 1:2 Ag(I):ligand was determined for each complex by the continuous variation Job's plot method using NMR spectroscopy. NMR studies were also carried out to investigate the fluxional behaviour of the Ag(I) complexes in solution. The biological activity of the silver(I) complexes and the corresponding ligands towards a clinical strain of Candida albicans MEN was studied using broth microdilution assays. Testing showed the choice of media and the duration of incubation were key determinants of the inhibitory behaviour towards Candida albicans, however, the difference between freshly …

A Qualitative Analysis Of Women's Postnatal Experiences Of Breastfeeding Supports During The Perinatal Period In Ireland, Niamh Lawlor, Lucia Prihodova, Deborah Byrne, Megan Etherton, Felicienne Rahill, Catie Wilson, Elizabeth J. O'Sullivan

Articles

Ireland has among the lowest rates of breastfeeding worldwide. Despite policies to support breastfeeding, breastfeeding initiation and exclusivity remain low in Ireland. Greater knowledge about support received in the maternity unit may—in part—shed light on why this is so. Our aim was to analyse women's experiences of the breastfeeding supports available in the early postnatal period in Ireland. We conducted an analysis of an open-ended question on a cross-sectional survey about breastfeeding support conducted in the Republic of Ireland in 2022. Participants were asked to provide comments about the breastfeeding support they received in the maternity unit or during your …

Systematic Review Of Necrophilia Aetiology Focusing On The Link Between Childhood Sexual Abuse And Necrophiliac Behaviours, Sophie Foxcroft

Theses : Honours

Sexual attraction to corpses is a disturbing concept to those who do not achieve sexual gratification from the stimuli. Due to this reason, as well as ethical concerns with relations and methods of obtaining, there has been little to no research on correlations between behaviours and psychological concepts. This is especially evident since the 1980s after the bulk of the literature on necrophilia was published. This systematic review looked at the existing literature on necrophilia and, in addition to reviewing the aetiology, aimed to identify cases that included individuals' upbringings and childhoods. Out of all existing literature, only 11 sources …

Development Of Holographic Recording Material For Fabrication Of Solar Concentrators For Micro Satellites, Brian Rogers

Doctoral

Holographic solar concentration has been a topic of increasing interest over recent years because of the lightweight and physically compact nature of holograms, which gives them an advantage over other, conventional concentration methods. As holographic recording materials develop further, their characteristics prove to meet the demands required of them to make more effective holographic solar concentrators. The development of photovoltaics in tandem with holographic materials has led to a host of solar concentrating device designs that take advantage of the unique properties of diffractive optics. Compared to refractive optics, holographic devices are more lightweight and compact. This makes holographic devices …

Structured Dialogue State Management For Task-Oriented Dialogue Systems, Anh Duong Trinh

Doctoral

Human-machine conversational agents have developed at a rapid pace in recent years, bolstered through the application of advanced technologies such as deep learning. Today, dialogue systems are useful in assisting users in various activities, especially task-oriented dialogue systems in specific dialogue domains. However, they continue to be limited in many ways. Arguably the biggest challenge lies in the complexity of natural language and interpersonal communication, and the lack of human context and knowledge available to these systems. This leads to the question of whether dialogue systems, and in particular task-oriented dialogue systems, can be enhanced to leverage various language properties. …

Towards The Development Of A Balanced Legislative Framework For Consumer Data Protection In Electronic Commerce: The Case Of The Sultanate Of Oman, Talib Al Kharusi

Doctoral

This research aims to investigate whether the law as it currently stands in Oman provides adequate legal protection for personal data, to determine the current obstacles facing the electronic commerce sector, and to identify ways of overcoming such challenges. The empirical focus of this study will be electronic commerce transactions between companies and consumers. In this regard, the research will explore the perceptions of the main stakeholders towards privacy regulation and what implications these have for the growth of electronic commerce in Oman. The privacy that this research aims to explore is a complex issue since it concerns human feelings …

Corrigendum: Human Mental Workload: A Survey And A Novel Inclusive Definition, Luca Longo, Christopher D. Wickens, Gabriella Hancock, P. A. Hancock

Articles

In the published article, the name of Gabriella Hancock was incorrectly written as “Gabriela M. Hancock.” The correct name is “Gabriella Hancock.” In the published article, there was also an error in the author list as published. Gabriella Hancock was listed as the last author, but should have been listed as third author. P. A. Hancock was listed as third author but should be listed as the last author. The corrected author list appears below. Luca Longo1, Christopher D.Wickens, Gabriella Hancock and P. A. Hancock. The authors apologize for this error and state that this does not change the scientific …

Do Games Reduce Math Anxiety? A Meta-Analysis, Pierpaolo Dondio, Viacheslav Filonenko, Mariana Rocha

Articles

In this paper, we meta-analyse the empirical evidence about the effectiveness of game-based interventions to reduce students' level of math anxiety. After performing a search for randomised controlled studies relevant to game-based intervention for math anxiety, 16 experimental studies with a total of 686 participants described in 11 peer-review articles met the selection criteria.A random-effects meta-analysis indicated a small and non-significant reduction of math anxiety (mean effect size ES=-0.32, CI=[-0.64,0.01]). The results were moderated by several factors: non-digital games were more effective, while digital games had a negligible mean effect size of $ES=-0.13$, $CI=[-0.33,0.08]$. The effect size was moderated also …

An Integrated Model For Information Adoption&Trust In Mobile Social Commerce, Fulya Acikgoz, Abdelsalam Busalim, James Gaskin, Shahla Asadi

Articles

ABSTRACT Despite the growing importance of mobile social commerce (ms-commerce), little research has been conducted on the effects of informational and social factors on users’ post-adoption behavior. We, therefore, build on the understanding of mobile social commerce in the UK market and how it affects users’ post-adoption behaviors. Our theoretical model leverages the information adoption model, social support theory, and social influence theory. Data was gathered from 377 ms-commerce users from the UK and analyzed via Partial Least Squares (PLS-SEM). The research findings show that both informational and social factors have a positive impact on information adoption in ms-commerce apps. …

A Multi–Objective Gaining–Sharing Knowledge-Based Optimization Algorithm For Solving Engineering Problems, Nour Elhouda Chalabi, Abdelouahab Attia, Khalid Abdulaziz Alnowibet, Hossam Zawbaa, Hatem Masri, Ali Wagdy Mohamed

Articles

Metaheuristics in recent years has proven its effectiveness; however, robust algorithms that can solve real-world problems are always needed. In this paper, we suggest the first extended version of the recently introduced gaining–sharing knowledge optimization (GSK) algorithm, named multiobjective gaining–sharing knowledge optimization (MOGSK), to deal with multiobjective optimization problems (MOPs). MOGSK employs an external archive population to store the nondominated solutions generated thus far, with the aim of guiding the solutions during the exploration process. Furthermore, fast nondominated sorting with crowding distance was incorporated to sustain the diversity of the solutions and ensure the convergence towards the Pareto optimal set, …

Survey Data On Dysfunctional Attitudes, Personality Traits, And Agreement With Persuasive Techniques, Annye Braca, Pierpaolo Dondio

Articles

Persuasion techniques play a vital role in human commu- nication, influencing various aspects of our lives. With the increasing prevalence of digital platforms, these techniques have permeated online spaces such as websites, mobile apps, games, and social media. This article presents a dataset col- lected via a survey, designed to gather information about in- dividuals’ demographics, personality traits, dysfunctional at- titudes, and their responses to statements embedded with persuasion techniques. Core messages promoting paid news subscriptions, blood donations, and exercise serve as the fo- cus, while definitions and examples of persuasive techniques are provided. By analyzing this comprehensive dataset, re- …

Cognitive Engagement In Learning And Its Relationship To Cognitive Test Anxiety In Online Learning Courses During Coronavirus Pandemic Among University Students, Nafez Bukaiei

Journal of Educational and Psychological Studies

Abstract: The study aimed to reveal the relationship between cognitive engagement in learning and cognitive test anxiety in online learning courses among students of Faculty of Educational Sciences and Arts / UNRWA in Jordan. It also aimed to identify the level of cognitive engagement in learning and the level of cognitive test anxiety based on the variables of gender, faculty, and school year level. To achieve the study objectives, the researcher used two scales, the first measure was cognitive engagement in learning and the second measure was cognitive test anxiety. The study sample consisted of (n=262) male and female students. …

Problematizing Progress: Building A Postcapitalist Present, Cole G. Shepard

Cal Poly Humboldt theses and projects

In the past three decades, the term post-capitalism has found its way into several disciplines ranging from economics to feminist studies. Over these years, its use and definition have made a noticeable shift, from a focus on grassroots resistance meant to carve out noncapitalist spaces within a capitalist system to a focus on utilizing modern technology like automation and universal basic income to demand more freedom for the working class. This project traces the academic discourses of postcapitalism in the United States today. I analyze who is using the term and how to understand postcapitalism’s place in a larger movement/series …

Teaching Dystopia In Dystopian Realities: Trauma-Informed Pedagogy And The Dystopian Novel After Covid-19, Emily Rose Lavrador

Cal Poly Humboldt theses and projects

This project advocates for a trauma-informed approach when teaching dystopian literature, particularly those with plague or pandemic plots. To have a truly student-centered approach in the classroom, trauma-informed pedagogy is necessary for students not only to learn comfortably, but to actively be creative or retain information.

Dystopian literature is assigned and consumed at pervasive rates; this popularity calls for additional attention to its teaching. The survey data presented in this project shows that 68 of 100 students had been assigned one or more dystopian texts through school years 2020 onwards, and 72 additionally were seeking out the dystopian genre on …