Digital Commons Network^™

Exploring Rosella (Hibiscus Sabdariffa L.) Calyx Extracts As Natural Dye And Antioxidants In Lip Cream Product: Formulation And Evaluation, Donna Maretta Ariestanti, Abdul Mun'im, Joshita Djajadisastra, Riska Amalia Putri Hutami, Redhalfi Fadhila, Richard Johari James

Pharmaceutical Sciences and Research

Rosella, also known as Hibiscus sabdariffa L., is a plant that contains anthocyanin compounds in its calyx, which are known for their antioxidant properties. These compounds give the plant a captivating red color and can be used as natural dyes. This study aimed to exploit anthocyanins in rosella calyx as natural dyes and antioxidants in lip cream product. The formulations employed extracts from rosella calyx, a viscous extract from maceration in 96% ethanol (F1) and a commercially available powdered rosella extract (F2). Evaluation on the formulations demonstrated that both F1 and F2 effectively maintained the color integrity of the lip …

Subchronic Toxicity Study Of Sterculia Rubiginosa Zoll. Ex Miq. Leaves Extract, Rini Prastiwi, Ester Hidayati, Riska Anggraini, Cut Mauliza, Ita Anggraini, Ema Dewanti

Pharmaceutical Sciences and Research

Ki hampelas (Sterculia rubiginosa Zoll. Ex Miq.) is traditionally used as an antiasthma. It also reported has antioxidant and nephroprotective activity. This study was conducted to evaluate the subchronic toxicity of the leaf extract of ki hampelas. The extract was orally administered to male and female Sprague-Dawley rats at doses of 50, 200, and 400 mg/kg bodyweight (BW) per day for 28 days. The rats were divided into four groups, consist of consist of normal group (Na CMC 0.5%), dose 1 (50 mg/kg BW), dose 2 (200 mg/kg BW), and dose 3 (400 mg/ kg BW) of extract. The …

Antioxidant Activities Of Roja Herbal Tea: Combination Of Rosella Flower (Hibiscus Sabdariffa L.) And Ginger Rhizome (Zingiber Officinale Rosc.), Wahyu Widowati, Teresa Liliana Wargasetia, Teddy Marcus Zakaria, Michael Sebastian Gunadi, Nathanael Halim, Sherly Santiadi, Hanna Sari Widya Kusuma, Nida Firyal Fauziyah

Pharmaceutical Sciences and Research

Herbal teas and plant-based medicines have been widely used worldwide for their therapeutic and healing qualities. Rosella (Hibiscus sabdariffa L.) has various benefits in preventing digestive problems, liver disease, fever, and others. Ginger (Zingiber officinale Rosc.) or known as jahe in Indonesia is believed to benefit numerous clinical conditions linked to oxidative stress, including pancreatitis, hypertension, diabetic kidney disease, Alzheimer’s disease, and tumor development. They have been utilized in traditional medical practice to treat conditions such as fever, nausea, and headaches. In this study, we aimed to determine the antioxidant activities of rosella flower tea, ginger tea, and …

Study Of Anti-Hyperuricemia, Anti-Inflammatory, And Anti-Nociceptive Effects Of Hylocereus Undatus Stem Bark Extract In Animal Models, Tri Wahyuni, Sartika Harka Putri, Anton Bahtiar

Pharmaceutical Sciences and Research

Dragon fruit, known as Hylocereus undantus (HU), has traditionally been utilized in Banyuwangi, East Java, Indonesia, for addressing gout and rheumatism. Despite its empirical use, there is a lack of reported pharmacological research on this plant. This study aimed to explore the properties of HU extract in treating hyperuricemia, inflammation, and pain. Adenine-potassium oxonate-induced mice were employed to evaluate anti-hyperuricemia activity, measuring uric acid, blood urea nitrogen (BUN), and creatinine serum levels. Carrageenan-induced paw edema in rats was used to assess anti-inflammatory activity, while acetic acid-induced abdominal writhing and hot plate tests were conducted to investigate anti-nociceptive effects. The results …

Perlindungan Hukum Irregular Migrant Workers Indonesia Dalam Prespektif Hak Asasi Manusia, Hana Nur Efsari

Jurnal Hukum & Pembangunan

The increase in migrant workers is also accompanied by an increase in various violations of the human rights of migrant workers. Problems of human rights violations are becoming more serious for Irregular Migrant Workers, hence the need for appropriate measures to ensure the protection of their human rights. As an international entity, states are burdened with full rights and responsibilities in protecting, upholding and fulfilling the human rights of precarious migrant workers. Although in Law no. 18 of 2017 concerning the Protection of Migrant Workers does not accommodate non-permanent migrant workers, but they are still individuals whose rights are protected …

Status Hukum Crew Interactive Mobile Companion (Cimon) Sebagai Kecerdasan Buatan Dalam Misi Luar Angkasa Di International Space Station (Iss) Berdasarkan Hukum Ruang Angkasa, Mochamad Rizcky Patria Putra, Irawati Handayani

Jurnal Hukum & Pembangunan

Humans require assistance to support the tasks assigned to them to achieve the predetermined success in a space mission. Consequently, humans have developed artificial intelligence technology. One of the AI technologies utilized is the Crew Interactive Mobile Companion (CIMON), which results from collaboration between several space agencies and organizations, both government and private. Based on space law regulations, CIMON AI raises questions as it serves two main functions in space law: as an astronaut with a legal personality and as an object launched into space. This study aims to examine the legal status of CIMON AI in space law and …

Hak Warga Masyarakat Terhadap Kebijakan Pemutusan Akses Penyelenggara Sistem Elektronik Lingkup Privat Yang Tidak Terdaftar, Rinalvin Achmad Wiryawan

Jurnal Hukum & Pembangunan

The policy of terminating access to Private Scope Electronic System Providers (Private Scope PSE), to several internet platforms including: Paypal, Yahoo, Epic Games, Steam, Dota, Counter Strike, Xandr.com, and Origin, which occurred on July 30, 2022. The termination of Private Scope PSE Access is due to the unregistered Private Scope PSE, whose provisions are regulated in the Permenkominfo PSE Private Scope. The policy of terminating access to the Private Scope PSE by the government is detrimental to citizens as users of the Private Scope PSE platform services whose access is terminated by the Government. Citizens have the right to communicate …

Putusan Pengadilan Mengenai Biaya Ganti Rugi Lingkungan: Aplikasinya Dalam Pemulihan Lingkungan, Rizqya Nafila Putri, Dadang Epi Sukarsa, Imamulhadi Imamulhadi

Jurnal Hukum & Pembangunan

Abstract

Indonesia through Law Number 32 of 2009 concerning Environmental Protection and Management regulates the government has the right to file claims for compensation and certain actions. Minister of the Environment Regulation Number 7 of 2014 concerning Compensation for Environmental Pollution and/or Damage, as a derivative regulation, regulates that environmental compensation costs that have been paid are entered into the Treasury Fund as Non-Tax State Revenue (PNBP). This research identifies the mechanism for using environmental compensation costs, the implementation of court decisions containing environmental compensation before Supreme Court Regulation Number 1 of 2023 concerning Guidelines for Adjudicating Environmental Cases, and …

The Impact Of Isil And Covid-19 On The Financial Performance Of Banks Listed On The Iraq Stock Exchange: A Comparative Study, Farqad Faisal Jadaan Sallal

Muthanna Journal of Administrative and Economics Sciences

This study aims to demonstrate the impact of the ISIL crisis and the COVID-19 pandemic crisis on the financial performance of banks listed on the Iraq Stock Exchange by comparing the profitability ratios of the banks in the research sample. In order to achieve this aim, a sample of 10 banks listed on the Iraq Stock Exchange was selected for the period 2011-2021. Using annual financial reports for the periods before and after the emergence of ISIS. Before and after the emergence of the COVID-19 pandemic, the profitability ratios were extracted (represented by return on assets, equity, and deposits). The …

Current Practice In The First Aid Management Of Epistaxis By Nursing Staff Working At The Emergency Departments Of Baghdad Hospitals, Baseem Natheer Abdulhadi

Muthanna Medical Journal

In otolaryngology, epistaxis—nosebleeds—are prevalent and severe. It is estimated that 10% to 60% of people will have at least one serious episode in their lives. This research will question people on how they stop nosebleeds and compare their replies to the medically recommended practice. This cross-sectional study assessed 105 paramedics in Baghdad's Emergency Wards, focusing on their demographics, education, and experience in managing epistaxis (nosebleeds). Key evaluation areas included the patient's position, pressure application on the nose, duration and method of pressure, use of nasal packs, ice application, and decision-making about when to call specialists. Their skills were scored on …

Evaluating Placement Experiences Of Mental Health Nursing Students Following The Implementation Of A Collaborative Learning In Practice (Clip) Model, Kerry Siau

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Exploring And Developing Critical Care Nurses’ Understanding Of ‘Big Data’ And Identifying Research Opportunities, Anisa M. Mursal

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Evaluating The Impact Of Physical Group Activities On Anxiety And Depression Across Psychiatric Inpatient Settings, Zeynep Demirtas

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Identifying The Need, Metrics, And Themes For Future Development Of A Fluid Balance Assessment Tool In End Stage Kidney Disease (Eskd): A Dietitian’S Perspective, Susan Laycock

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Exploring Staff Attitudes To Urinary Catheter Care: An Evidence Informed Change Project, Rashima Hamdan

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

The Nexus Between Teaching And Research: Exploring The Synergies That Drive Innovation, Joseph Ching Velasco

Asia-Pacific Social Science Review

No abstract provided.

A Conceptual Framework For Understanding Lake Governance: Lake’S People, Development, Conservation, And Government, Bing Baltazar C. Brillo

Asia-Pacific Social Science Review

Governance’s concept is well-established, multifarious, and too considerable in meanings, indicators, and frameworks, making it distinct to different people and unappealing to apply in lakes. Under this, governance ought to be reductionist-parsimony to be manageable and straightforward in refocusing the primary reference—lake governance. Lake governance’s concept is rarely utilized in scholarly literature nor acknowledged in the lake’s discourse. To ameliorate, the article intends to be a discourse—elucidate, understand, and contribute to lake governance’s analytical framework, respectively, the constituent’s interrelationship among the lake’s people, development, conservation, and the government, its most influential compartment. With this, lake governance asserts (a) development and …

Infrastructure Development For The Digital Silk Road (Dsr) And Its Implications For China Under The Belt And Road Initiative, Fakhar Hussain, Ali Imran, Zakar Hussain, Muhammad Ikramullah Khan

Asia-Pacific Social Science Review

No abstract provided.

Mapping The Contemporary Writer: A Survey Of Critical Works On Tash Aw’S Novels, Yuanyu Shi, Qiuchen Xu

Asia-Pacific Social Science Review

No abstract provided.

Model Discovery Learning Untuk Meningkatkan Critical Thinking Dan Literasi Membaca Dalam Pembelajaran Bahasa Indonesia Siswa Sekolah Dasar, Imroatul Mufidah, Suyono Suyono, Ratna Ekawati

Journal of Innovation and Teacher Professionalism

Tujuan dari penelitian ini adalah meningkatkan critical thinking melalui model discovery learning dan kemampuan literasi membaca melalui model discovery learning. Penelitian ini menggunakan pendekatan kualitatif, sedangkan jenis metodenya adalah Classroom Action Research (CAR). Penelitian dilakukan dalam dua siklus, masing-masing siklus terdiri empat tahapan yaitu perencanaan (Planning), tindakan (Action), pengamatan (Observation), dan refleksi (Reflection). Pengumpulan data menggunakan observasi dan tes. Adapun teknik analisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa pada siklus I hasil tes kemampuan berpikir kritis siswa dengan rerata 78,10 di siklus II meningkat menjadi 84,82 persen dengan katageri 100 persen siswa dinyatakan …

Peran Kepemimpinan Kepala Sekolah Dalam Upaya Meningkatkan Disiplin Kerja Guru Di Sekolah Dasar, Sofiatul Azkiyah, Berliana Henu Cahyani, Yuyun Yulia

Journal of Innovation and Teacher Professionalism

Penelitian ini bertujuan untuk mengetahui peranan, faktor penghambat dan pendukung serta solusi peran kepemimpinan kepala sekolah dalam upaya meningkatkan disiplin kerja guru di SD Negeri Kalbir. Jenis penelitian menggunakan kualitatif dengan bentuk deskriptif. Pengumpulan data dengan observasi, wawancara, dan dokumentasi. Subyek penelitian adalah kepala sekolah, guru kelas. Hasil penelitian menunjukkan: 1) Kepala sekolah menjalankan perannya sebagai pendidik dengan memberikan keteladanan dan meningkatkan profesionalisme guru; sebagai manajer yang merencanakan segala sesuatu yang berkaitan dengan sekolah; 2) Faktor penghambat; status sebagian guru masih honorer dan sarana prasarana yang belum lengkap, faktor pendukung adalah kepribadian guru yang baik; dan 3) Solusinya adalah dengan …

Bahan Ajar Berbasis Kearifan Lokal Nelayan Di Nusantara Untuk Meningkatkan Minat Belajar Siswa Sekolah Dasar, Dini Rosyada Mahmud

Journal of Innovation and Teacher Professionalism

Bahan ajar bagian penting untuk menunjang proses pembelajaran. Indonesia mempunyai kearifan lokal yang beragam contohnya tradisi kehidupan nelayan, namun keterbatasan materi dalam buku peserta didik membutuhkan pengembangan bahan ajar berbasis kearifan lokal. Metode pengem­bangan menggunakan model ADDIE (Analysis-Design-Development-Implement-Evaluate). Teknik pengumpulan data menggunakan observasi, wawancara, dokumentasi, validasi ahli media, dan angket peserta didik. Teknik analisis data menggunakan kualitatif dari hasil pengamatan observasi, wawancara guru dan peserta didik, saran dan masukan dari dosen ahli bahan ajar. Sedangkan data kuantitatif berupa angka dari pengisian angket. Hasil validasi ahli media bahan ajar diperoleh 92,5 persen dengan kriteria sangat layak digunakan dan validasi ahli materi …

Lkpd Elektronik Berbasis Hots Untuk Siswa Kelas Iii Dengan Tema Praja Muda Karana Subtema Aku Suka Berpetualang Pada Pembelajaran 2 Di Sekolah Dasar, Mutik Selviana, Ladamay Iskandar, Yuniasih Nury

Journal of Innovation and Teacher Professionalism

Tujuan dari penelitian ini adalah mendeskripsikan kelayakan, kepraktis­an dan kemenarikan dan kefektivan bahan ajar LKPD Elektronik. Metode penelitian yang digunakan peneliti yaitu penelitian pengembangan dengan penggunaan model 4D dengan 4 tahapan yaitu: tahap pendefenisisan (Define), tahap perancangan (Design), tahap pengembangan (Development), tahap penyebaran (Dis­seminate). Namun peneliti hanya menggunakan 4D sampai dengan tahap pengembangan. Subjek uji coba adalah 10 siswa kelas III SDN Bandungrejosari 01 Kota Malang. Instrument yang digunakan dalam penelitian ini yaitu angket dan dokumentasi. Angket terdiri dari ahli materi, ahli media, ahli bahasa, praktisi (guru) dan angket respon siswa. Teknik analisis data menggunakan deskriptif kuan­titatif dan kualitatif. Hasil …

Meningkatkan Hasil Belajar Melalui Model Pembelajaran Problem Based Learning Pada Muatan Ipa Perkembangbiakan Tumbuhan Pada Siswa Kelas Vi, Indah Sukowati

Journal of Innovation and Teacher Professionalism

Penelitian ini bertujuan mendeskripsikan peningkatan hasil belajar siswa dengan model pembel­ajaran Problem Based Learning (PBL) pelajaran IPA. Penelitian Tindakan Kelas (PTK) yang dilaksa­nakan adalah dua siklus, setiap siklus terdiri empat tahap yaitu perencanaan, pelaksanaan, observasi dan refleksi. Subyek penelitian siswa kelas VI A SDN Lowokwaru 3 berjumlah 28 siswa Indikator keberhasilan peningkatan hasil belajar siswa pada penelitian dilihat dari siswa tuntas KKM dengan nilai 75. Hasil penelitian menunjukkan terdapat peningkatan hasil belajar siswa ditunjukkan dari data tes yaitu nilai rata-rata siswa pada prasiklus sebesar 63,75, meningkat pada siklus I menjadi 80,30, dan pada siklus II nilai rata-rata siswa meningkat menjadi …

The Increasing Role Of Technology In Teaching And Learning Activities In Higher Education, Gary J. Burkholder, Erwin Krauskopf

Higher Learning Research Communications

We are pleased to publish the second regular issue (Volume 13, Issue 2) of Higher Learning Research Communications (HLRC) for 2023. If there is a common theme that emerged from the COVID-19 pandemic, it is the increased role that technology did and will continue to play in teaching and learning activities in tertiary education. The range of articles reflects the interest in digital teaching and learning and includes the use of scaffolded simulations, the influence of immersive virtual reality in the classroom, and gamification. In addition, guidelines around instant messaging are proposed that should continue the conversation around the ethical …

Librarian' Understanding, Perception, And Attitudes Regarding Cloud Computing In Academic Libraries Punjab, Pakistan: A Survey, Shahid Mehmood, Prof.Dr.Rais Ahmed Samdani, Muhammad Wahid

Library Philosophy and Practice (e-journal)

People who used the University of Sargodha library were asked what they thought about Cloud Computing for the study. The goal of this study was to find out more about how people feel about cloud computing in general and how well they understand it. There were both descriptive and quantitative methods used in the study. Over sixty-nine people were asked to take part in the study, and 65 were randomly picked from the census. The study used SPSS version 21 to turn table data with numbers into percentages and rates. Most people know what Cloud Computing is and how it …

Utilization Of Media Resources For Instructions Among Library Educators In Adult Learning Centers In Awka South Lga, Eliezer Chukwuyere Agim, Solomon Irieguna, Cyprainmary Chukwudebelu Chivuzo

Library Philosophy and Practice (e-journal)

The study was designed to ascertain the utilization of media resources for instructions among library educators in adult learning centers in Awka South LGA. A descriptive survey research design was used for the study. The sample population comprised of 14 adult educators selected randomly from adult learning center in Awka South LGA using the purposive sampling technique. A structured questionnaire on a four (4) – point Likert scale was used for collection of data. The instrument was subjected to face validation and pilot test using Cronbach Alpha which gave a reliability coefficient value of 0.96. Data collected from the study …

Mir-142: A Master Regulator In Hematological Malignancies And Therapeutic Opportunities, Wilson Huang, Doru Paul, George A Calin, Recep Bayraktar

Faculty, Staff and Student Publications

MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently associated with the onset and progression of human cancers. miR-142, an ultra-conserved miRNA with both active -3p and -5p mature strands and wide-ranging physiological targets, has been the subject of countless studies over the years. Due to its preferential expression in hematopoietic cells, miR-142 has been found to be associated with numerous types of lymphomas and leukemias. This review elucidates the multifaceted role of miR-142 in human physiology, its influence on hematopoiesis and hematopoietic cells, and its intriguing involvement in exosome-mediated miR-142 transport. Moreover, we offer a comprehensive …

A Real-World Study Of Pneumonitis In Non-Small Cell Lung Cancer Patients Receiving Durvalumab Following Concurrent Chemoradiation, Neha Akkad, Theodore S. Thomas, Suhong Luo, Eric Knoche, Kristen M. Sanfilippo, Jesse W. Keller

2020-Current year OA Pubs

BACKGROUND: Locally advanced non-small cell lung cancer (LA-NSCLC) treated with the programmed death-ligand 1 inhibitor durvalumab has been associated with significant rates of pneumonitis, which has led to higher rates of discontinuation of therapy in real-world populations. Thus far there has been no consensus in the literature on the impact of pneumonitis on survival.

METHODS: This is a retrospective cohort study of veterans receiving durvalumab between 12/5/2017 and 4/15/2020. Participants were identified using VINCI data services. Patients were followed through 9/14/2021. Development of clinical pneumonitis was assessed through review of documentation and graded using CTCAE 4.0 criteria. Univariate logistic regression …

Inhaled Medications For Chronic Obstructive Pulmonary Disease Predict Surgical Complications And Survival In Stage I Non-Small Cell Lung Cancer, Steven Tohmasi, Daniel B. Eaton, Brendan T Heiden, Nikki E. Rossetti, Valerio Rasi, Su-Hsin Chang, Yan Yan, Deepika Gopukumar, Mayank R. Patel, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri, Martin W. Schoen

2020-Current year OA Pubs

BACKGROUND: Lung function is routinely assessed prior to surgical resection for non-small cell lung cancer (NSCLC). Further assessment of chronic obstructive pulmonary disease (COPD) using inhaled COPD medications to determine disease severity, a readily available metric of disease burden, may predict postoperative outcomes and overall survival (OS) in lung cancer patients undergoing surgery.

METHODS: We retrospectively evaluated clinical stage I NSCLC patients receiving surgical treatment within the Veterans Health Administration from 2006-2016 to determine the relationship between number and type of inhaled COPD medications (short- and long-acting beta2-agonists, muscarinic antagonists, or corticosteroids prescribed within 1 year before surgery) and postoperative …