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Volume 6, Issue 1 (2023) Criminal Justice Agents And Responsibility, Colleen Berryessa, Elizabeth Griffiths, Kaitlen Hubbard, Deena A. Isom, Kateryna Kaplun, Hiuxuan Li, Siyu Liu, Esther Nir, Heather L. Scheuerman, Rachel Schumann, Sandy Xie, Carolyn Yule

International Journal on Responsibility

This special issue of the International Journal on Responsibility (IJR) advances scholarship on the various ways responsibility infuses the roles of criminal justice agents. As the inaugural issue of my tenure as Editor-in-Chief, Volume 6 deepens our understanding of responsibility in the context of the criminal justice system, thereby fulfilling IJR’s aim and scope. Specifically, the articles highlight issues of responsibility within each component of the criminal justice system: police, courts, and corrections.

Metagenomic Analysis Unveils The Microbial Landscape Of Pancreatic Tumors, Sheema Khan, Goutam Banerjee, Saini Setua, Daleniece Jones, Bhavin Chauhan, Anupam Dhasmana, Pratik Banerjee, Murali M. Yallapu, Stephen Behrman, Subhash C. Chuahan

School of Medicine Publications

The composition of resident microbes in the human body is linked to various diseases and their treatment outcomes. Although studies have identified pancreatic ductal adenocarcinoma (PDAC)-associated bacterial communities in the oral and gut samples, herein, we hypothesize that the prevalence of microbiota in pancreatic tumor tissues is different as compared with their matched adjacent, histologically normal appearing tissues, and these microbial molecular signatures can be highly useful for PDAC diagnosis/prognosis. In this study, we performed comparative profiling of bacterial populations in pancreatic tumors and their respective adjacent normal tissues using 16S rRNA-based metagenomics analysis. This study revealed a higher abundance …

Assessment Of Deficits In Specific Cognitive Domains In Older Adults Living With Hiv., Andrea Reyes-Vega, Harideep Samanapally, Rishikesh Rijal, Stephen P. Furmanek, Christopher B. Shields, Brandon C. Dennis, Smita Ghare, Shirish Barve

Faculty and Staff Scholarship

A significant proportion of people living with HIV (PLWH) have cognitive impairment. Moreover, approximately 70% of PLWH in the United States will be ≥50 years old by 2030, raising concerns of a higher incidence of dementia as they age. Accordingly, there is a clinical need to monitor their cognitive status. The aim of this study was to delineate specific cognition areas impacted in OALWH with a clinical diagnosis of neurocognitive impairment. We used a comprehensive set of tests (paper and NIH Toolbox Cognition Battery), to assess different cognitive domains in a total of 25 OALWH ≥ 50 years. 64% were …

Exploring Attitudes Toward “Sugar Relationships” Across 87 Countries: A Global Perspective On Exchanges Of Resources For Sex And Companionship, Norbert Meskó, Marta Kowal, András Láng, Ferenc Kocsor, Szabolcs A. Bandi, Adam Putz, Piotr Sorokowski, David A. Frederick, Felipe E. García, Leonardo A. Aguilar, Anna Studzinska, Chee Seng Tan, Biljana Gjoneska, Taciano L. Milfont, Bulut M Topcu, Dmitry Grigoryev, Toivo Aavik, Mahmoud Boussena, Alan D.A. Mattiassi, Reza Afhami, Rizwana Amin, Roberto Baiocco, Hamdaoui Brahim, Ali R. Can, Joao Carneiro, Hakan Çetinkaya, Dimitri Chubinidze, Eliane Deschrijver, Yahya Don, Dmitrii Dubrov, Izzet Duyar, Marija Jovic, Julia A. Kamburidis, Farah Khan, Hareesol Khun-Inkeeree, Maida Koso-Drljevic, David Lacko, Karlijn Massar, Mara Morelli, Jean C. Natividade, Ellen K. Nyhus, Ju Hee Park, Farid Pazhoohi, Ekaterine Pirtskhalava, Koen Ponnet, Pavol Prokop, Dušana Šakan, Singha Tulyakul, Austin H. Wang, Sibele D. Aquino, Derya D. Atamtürk, Nana Burduli, Antonio Chirumbolo, Seda Dural, Edgardo Etchezahar, Moharrampour N Ghahraman, Balazs Aczel, Luca Kozma, Samuel Lins, Efisio Manunta, Tiago Marot, Moises Mebarak, Kirill G. Miroshnik, Katarina Misetic, Marietta Papadatou-Pastou, Bence Bakos, Fatima Zahra Sahli, Sangeeta Singh, Çağlar Solak, Tatiana Volkodav, Anna Wlodarczyk, Grace Akello, Marios Argyrides, Ogeday Çoker, Katarzyna Galasinska, Yepes T Gómez, Aleksander Kobylarek, Miguel Landa-Blanco, Marlon Mayorga, Barış Özener, Ma Criselda T. Pacquing, Marc Eric S. Reyes, Ayşegül Şahin, William Tamayo-Agudelo, Gulmira Topanova, N/A Toplu-Demir

School of Psychology

The current study investigates attitudes toward one form of sex for resources: the so-called sugar relationships, which often involve exchanges of resources for sex and/or companionship. The present study examined associations among attitudes toward sugar relationships and relevant variables (e.g., sex, sociosexuality, gender inequality, parasitic exposure) in 69,924 participants across 87 countries. Two self-report measures of Acceptance of Sugar Relationships (ASR) developed for younger companion providers (ASR-YWMS) and older resource providers (ASR-OMWS) were translated into 37 languages. We tested cross-sex and cross-linguistic construct equivalence, cross-cultural invariance in sex differences, and the importance of the hypothetical predictors of ASR. Both measures …

Simvastatin In Critically Ill Patients With Covid-19, Thomas E Hills, Elizabeth Lorenzi, Lindsay R Berry, Murali Shyamsundar, Farah Al-Beidh, Djillali Annane, Yaseen Arabi, Diptesh Aryal, Carly Au, Abigail Beane, Zahra Bhimani, Marc Bonten, Charlotte A Bradbury, Frank M Brunkhorst, Aidan Burrell, Meredith Buxton, Carolyn S Calfee, Maurizio Cecconi, Allen C Cheng, Matthew E Cove, Michelle A Detry, Lise J Estcourt, Mark Fitzgerald, Ewan C Goligher, Herman Goossens, Cameron Green, Rashan Haniffa, David A Harrison, Madiha Hashmi, Alisa M Higgins, Christopher Horvat, David T Huang, Nao Ichihara, Deva Jayakumar, Peter S Kruger, François Lamontagne, Lamprini Lampro, Patrick R Lawler, John C Marshall, Alexina J Mason, Anna Mcglothlin, Shay Mcguinness, Zoe K Mcquilten, Bryan J Mcverry, Paul R Mouncey, Srinivas Murthy, Matthew D Neal, Alistair D Nichol, Cecilia M O'Kane, Rachael L Parke, Jane C Parker, Ebenezer Rabindrarajan, Luis F Reyes, Kathryn M Rowan, Hiroki Saito, Marlene Santos, Christina T Saunders, Christopher W Seymour, Manu Shankar-Hari, Pratik Sinha, B Taylor Thompson, Alexis F Turgeon, Anne M Turner, Frank Van De Veerdonk, Sebastian Weis, Ian S Young, Ryan Zarychanski, Roger J Lewis, Colin J Mcarthur, Derek C Angus, Scott M Berry, Lennie P G Derde, Steve A Webb, Anthony C Gordon, Daniel F Mcauley

Faculty, Staff and Student Publications

BACKGROUND: The efficacy of simvastatin in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear.

METHODS: In an ongoing international, multifactorial, adaptive platform, randomized, controlled trial, we evaluated simvastatin (80 mg daily) as compared with no statin (control) in critically ill patients with Covid-19 who were not receiving statins at baseline. The primary outcome was respiratory and cardiovascular organ support-free days, assessed on an ordinal scale combining in-hospital death (assigned a value of -1) and days free of organ support through day 21 in survivors; the analyis used a Bayesian hierarchical ordinal model. The adaptive design included prespecified statistical …

Distinct Gene Expression Signatures Comparing Latent Tuberculosis Infection With Different Routes Of Bacillus Calmette-Guérin Vaccination, Richard F Silver, Mei Xia, Chad E Storer, Jessica R Jarvela, Michelle C Moyer, Azra Blazevic, David A Stoeckel, Erin K Rakey, Jan M Tennant, Johannes B Goll, Richard D Head, Daniel F Hoft

2020-Current year OA Pubs

Tuberculosis remains an international health threat partly because of limited protection from pulmonary tuberculosis provided by standard intradermal vaccination with Bacillus of Calmette and Guérin (BCG); this may reflect the inability of intradermal vaccination to optimally induce pulmonary immunity. In contrast, respiratory Mycobacterium tuberculosis infection usually results in the immune-mediated bacillary containment of latent tuberculosis infection (LTBI). Here we present RNA-Seq-based assessments of systemic and pulmonary immune cells from LTBI participants and recipients of intradermal and oral BCG. LTBI individuals uniquely display ongoing immune activation and robust CD4 T cell recall responses in blood and lung. Intradermal BCG is associated …

Mapping Media And Information Literacy Skills During And After Covid-19, With Special Reference To Online Education, And Commerce And Trade, Omwoyo Bosire Onyancha

Journal of Media Literacy Education

This paper examines literature from the COVID-19 period (2020-2022) to outline prevalent themes and essential competencies in the post-COVID era. Employing informetrics within a quantitative research approach, the study scrutinizes Scopus database data using COVID-19, e-learning, e-commerce, and media and information literacy terms. Results reveal a surge in scholarly focus on e-commerce, online learning, e-health, and ICTs, including social media. Identified were 355 media and information literacy terms, with digital, information, health, and media literacy at the forefront. Moreover, 244 corresponding competencies and skills were noted. The study emphasizes the necessity for comprehensive media and information literacy programs, diverse competencies, …

Discerning The Roles Of Novel Glycosyltransferases In The Pathogenic Yeast Cryptococcus Neoformans, Liza Loza

Arts & Sciences Graduate Student Theses and Dissertations

Cryptococcus neoformans (Cn) is an opportunistic fungal pathogen responsible for over 112,000 deaths each year. This yeast is ubiquitous in the environment, where it is particularly associated with soil, trees, and bird excreta. When a susceptible host inhales infectious particles, Cn can proliferate in the lungs before disseminating to the brain to cause an often-fatal meningoencephalitis. Cryptococcosis primarily afflicts those living with uncontrolled HIV/AIDS, accounting for ~15% of AIDS-related mortality. The antifungals available to treat this devastating disease are few in number, toxic to patients, and largely inaccessible in resource-limited settings. The major virulence factor of Cn is its complex …

Nanoparticles Used In Treatment And Diagnosis Of Leishmaniasis In Iraq: A Review, Harith S. Al-Warid, Layla M. Hasan

Al-Esraa University College Journal for Medical Sciences

The aim of this paper is to identify Nano-particles that have been used in diagnosis and treatment of leishmaniasis in Iraq. All experiments conducted in this field were based on the following nanoparticles: gold nanoparticles, silver nanoparticles, zinc nanoparticles, and sodium chloride nanoparticles. Most of these experiments were reviewed in terms of differences in the concentrations of nanoparticles and the method that was used in the experiments whether it was in vivo or in vitro. These particles used in most experiments succeeded in inhibiting the growth of Leishmania parasites.

Pseudomonas Aeruginosa Epidemiology And Antibiotic Resistance: A Five Years Retrospective Study In Iraq., Huda Ghassan Hameed

Al-Esraa University College Journal for Medical Sciences

One of the leading causes of diseases and deaths across the world are bacterial infections, and the situation is only going to grow worse as antibiotic resistance spreads. Antimicrobial resistance must be closely monitored so as to control the spread of multi-antibiotic-resistant microorganisms. As a result, the goal for the study was to estimate the prevalence of Pseudomonas aeruginosa infection on top of that to look into the antibacterial pattern over the last five years. This retrospective investigation was carried out in various hospitals in Iraq like Central Children's Teaching Hospital for Children, Al Kindi Teaching Hospital, Al-Numan Hospital, Yarmouk …

Evaluation Of A Targeted Covid-19 Community Outreach Intervention: Case Report For Precision Public Health, Isela De La Cerda, Cici X Bauer, Kehe Zhang, Miryoung Lee, Michelle Jones, Arturo Rodriguez, Joseph B Mccormick, Susan P Fisher-Hoch

Faculty, Staff and Student Publications

BACKGROUND: Cameron County, a low-income south Texas-Mexico border county marked by severe health disparities, was consistently among the top counties with the highest COVID-19 mortality in Texas at the onset of the pandemic. The disparity in COVID-19 burden within Texas counties revealed the need for effective interventions to address the specific needs of local health departments and their communities. Publicly available COVID-19 surveillance data were not sufficiently timely or granular to deliver such targeted interventions. An agency-academic collaboration in Cameron used novel geographic information science methods to produce granular COVID-19 surveillance data. These data were used to strategically target an …

The Potential For Development Of Clinically Relevant Microbial Resistance To Rifaximin-Α: A Narrative Review, Herbert L Dupont

Faculty, Staff and Student Publications

Rifaximin-α is a gut-targeted antibiotic indicated for numerous gastrointestinal and liver diseases. Its multifaceted mechanism of action goes beyond direct antimicrobial effects, including alterations in bacterial virulence, cytoprotective effects on host epithelial cells, improvement of impaired intestinal permeability, and reduction of proinflammatory cytokine expression via activation of the pregnane X receptor. Rifaximin-α is virtually non-absorbed, with low systemic drug levels contributing to its excellent safety profile. While there are high concentrations of drug in the colon, low water solubility leads to low colonic drug bioavailability, protecting the gut microbiome. Rifaximin-α appears to be more active in the bile-rich small bowel. …

Research On Geographical Landscape Design Of Ecological Civilization Construction In China, Wenzhong Zhang, Jianhui Yu

Bulletin of Chinese Academy of Sciences (Chinese Version)

As the fundamental goal of ecological civilization construction in the new era of China, the building of a Beautiful China is an important measure to promote the study of Chinese man-land relationships to a higher level and a new stage of development. This study takes the construction of ecological civilization of Beautiful China as the orientation, and carries on the frame design to the geographical landscape. The geographical landscape takes the elements of geoscience as the research object and makes a series of reasonable outlook about man-land system according to the interaction mechanism of human-land relationship and the influence of …

The Federal Government Must Revise Public Housing Policies To Protect Vulnerable Populations From Evictions, Caroline Grabowski

Population Health Research Brief Series

Over 100,000 Americans are now dying from drug overdoses annually, signifying that the goal of the 1986 Anti-Drug Abuse Act (ADAA) to end illicit drug use has not been achieved. What’s more, numerous statutes within the ADAA have created or worsened housing instability among people who use drugs and their families. This is because the ADAA allows public housing officials to use their own discretion when determining evictions and lease refusals and has disproportionately harmed individuals in public housing who did not participate in the drug-related activities that led to their eviction. This brief describes how the ADAA negatively affects …

Strategy To Increase Anti-Viral, Anti-Microbial, And Anti-Fungal Defense, Hana Totary-Jain

USF Patents

Disclosed herein are compositions and methods for inducing, promoting, or enhancing an immune response in a subject. For example, the disclosed compositions and methods can be used prophylactically to prevent viral/microbial infections or therapeutically to treat acute infections. In some embodiments, the disclosed method involves administering to the subject a composition comprising in vitro transcribed (IVT) RNA comprising short interspersed nuclear elements (SINEs), such as Alu repeats. In some embodiments, the disclosed compositions and methods can be used to induce, promote, or enhance any immune response in a subject, including an anti-viral, anti-microbial, anti-fungal, or anti-parasite response. In some embodiments, …

Traffic Congestion Analysis Using Sir Epidemic Model, Zani Anjani Rafsanjani, Ratna Herdiana, R Heru Tjahjana, Yogi Ahmad Erlangga

All Works

In this work, we propose a mathematical model to represent traffic congestion in the street under some consideration. A congestion problem in a city highway becomes a critical issue since congestion at one point affected congestion propagation on the other points. We focus on the propagation of traffic propagation by adopting the concept of disease spread using the SIR model. We consider that the disease in traffic problems is congestion. Meanwhile, vehicles that enter the highway are susceptible to congestion. In contrast, vehicles free from traffic jams represent individuals free from disease. The SIR model can explain the spread of …

The Lived Experiences Of The Newly Graduated Generation "Z": Registered Nurse Entering The Intensive Care Unit, Matthew Robert Loveitt

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to illuminate, understand, and describe the meaning of the lived experiences of Gen Z new graduate registered nurses (NGRNs) transitioning directly into the ICU in their first position as registered nurses. Duchscher’s stages of transitional theory and the Strauss-Howe generational theory provided this study’s theoretical framework, focusing on the Gen Z NGRN transition into practice. This study answered the following central research question: What is the lived experience of Gen Z NGRNs transitioning into the ICU work environment employed in their first position as registered nurses? Data were collected for this study …

Interlaboratory Comparison Of Pseudomonas Aeruginosa Phage Susceptibility Testing, Krupa Parmar, Lauren Komarow, Damon W Ellison, Andrey A Filippov, Mikeljon P Nikolich, Joseph R Fackler, Martin Lee, Anjna Nair, Priyesh Agrawal, Pranita D Tamma, Maria Souli, Scott R Evans, Kerryl E Greenwood-Quaintance, Scott A Cunningham, Robin Patel, Antibacterial Resistance Leadership Group

Faculty, Staff and Student Publications

Standardized approaches to phage susceptibility testing (PST) are essential to inform selection of phages for study in patients with bacterial infections. There is no reference standard for assessing bacterial susceptibility to phage. We compared agreement between PST performed at three centers: two centers using a liquid assay standardized between the sites with the third, a plaque assay. Four Pseudomonas aeruginosa phages: PaWRA01ø11 (EPa11), PaWRA01ø39 (EPa39), PaWRA02ø83 (EPa83), PaWRA02ø87 (EPa87), and a cocktail of all four phages were tested against 145 P. aeruginosa isolates. Comparisons were made within measurements at the two sites performing the liquid assay and between these …

The Impact Of The Covid-19 Pandemic For High School Counselors: A Phenomenological Investigation, Melissa Ann Jensen

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to discover the comprehensive effect that the COVID-19 pandemic had and may still be having on high school counselors in the Houston metropolitan area. Maslow’s Hierarchy of Needs theory guides this study as it notes an individual’s ability to advance toward self-actualization in one’s personal and professional life. The COVID-19 pandemic altered one’s ability to accomplish those steps. Interviews with high school counselors assisted in gathering personal experiences as to how much the COVID-19 pandemic impacted their ability to become their best selves, both personally and professionally. Two focus groups were conducted to …

The Necessity Of Spiritual Preparation In Short-Term Missions As It Correlates To Ministry Effectiveness, Brent Edward Allen

Doctoral Dissertations and Projects

There is a lack of resources available providing spiritual preparation training specifically for teams preparing for a STM with M4 Institute. The purpose of this action research project is two-fold. First, to develop a spiritual preparation resource for STM work in the Western Highlands of Guatemala. Second, to determine if providing spiritual preparation training for a team preparing for said STM work will improve the ministry effectiveness of the trip. An eight-week, five-phase intervention guide was created to implement with the focus group. This consisted of two in-person, on-site team trainings, three pre-trip Zoom team meetings, mid-trip communications with participants …

A Quantitative Study On The Impact Of Covid-19 On Drug Treatment Courts, Derek J. Kingsbury

Doctoral Dissertations and Projects

The purpose of this research study was to investigate how the COVID-19 pandemic impacted drug treatment courts (DTCs) in Pennsylvania. DTCs were created as an alternative to the traditional court system by allowing those convicted of a drug offense to receive treatment. Just as these DTCs were dealing with the opioid crisis, a new obstacle occurred in the form of the COVID-19 pandemic, forcing DTCs to adapt to the quickly evolving and changing mandates and policies implemented by the federal and local governments. The impact of the COVID-19 pandemic on these essential DTCs was examined using a therapeutic jurisprudence perspective. …

A Phenomenological Study In Understanding African American Spiritual Leaders And The Black Church On Elder Abuse, Cassandra R. Downey

Doctoral Dissertations and Projects

This qualitative study described how the Black Church and African American Spiritual Leaders in Milwaukee, Wisconsin, understood the issue of elder abuse and the Black Church's role in navigating education and resources to those who are victims or at risk. African-American Spiritual Leaders' role and leadership are integral in combating elder abuse among their older members of the church and society. African Americans have always placed a significant portion of their support in the church and frequently turn to them before considering other options. Acknowledging the church's and spiritual leaders' involvement in comprehending the awareness of elder maltreatment is essential …

Rotavirus-Mediated Dgat1 Degradation: A Pathophysiological Mechanism Of Viral-Induced Malabsorptive Diarrhea, Zheng Liu, Hunter Smith, Jeanette M Criglar, Antonio J Valentin, Umesh Karandikar, Xi-Lei Zeng, Mary K Estes, Sue E Crawford

Faculty, Staff and Students Publications

Gastroenteritis is among the leading causes of mortality globally in infants and young children, with rotavirus (RV) causing ~258 million episodes of diarrhea and ~128,000 deaths annually in infants and children. RV-induced mechanisms that result in diarrhea are not completely understood, but malabsorption is a contributing factor. RV alters cellular lipid metabolism by inducing lipid droplet (LD) formation as a platform for replication factories named viroplasms. A link between LD formation and gastroenteritis has not been identified. We found that diacylglycerol O-acyltransferase 1 (DGAT1), the terminal step in triacylglycerol synthesis required for LD biogenesis, is degraded in RV-infected cells by …

Overview Of Urinary Tract Infection Caused By Bacteria, Ahmed Talib Abdulkarem, Shaimaa M.S. Zainulabdeen, Saif Mazeel Abed

Muthanna Medical Journal

Urinary tract infections [UTIs], a significant public health concern, can be brought on by a wide variety of bacteria, including Escherichia coli, Proteus mirabilis, Enterococcus faecalis, Klebsiella pneumoniae, and Staphylococcus saprophyticus. The high recurrence rates and evolving antibiotic resistance of uropathogens constitute a serious threat to the financial burden of these disorders. Pathogens in urine can be detected using a variety of diagnostic approaches, which are broadly divided into laboratory-based and point-of-care [POC] detection methods. Many research institutions and companies working in this subject have strived to establish a rapid and accurate pathogen identification because traditional approaches may be time-consuming. …

Perceptions Regarding Drinking Water Quality And Its Effects On Human And Animal Health Among Plain-Sect Community Members, Anil Kumar Chaudhary, Parmveer Singh, Sharmistha Basak

Journal of Amish and Plain Anabaptist Studies

The quality of drinking water can affect human and animal health, and plain-sect populations may be more susceptible than other rural populations due to their use of traditional farm management practices and their reliance on well water. Therefore, an interdisciplinary team conducted a pilot study to understand the status of existing drinking water quality, community perceptions regarding causes of water deterioration, its associated effect on human and animal health, and solutions to address such challenges. The study included water testing and a focus group discussion with plain-sect community members. The findings revealed that participants perceived the drinking water quality as …

The Potential Of Stem Cell Therapy In Multiple Sclerosis Treatment: A Review, Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 people. Symptoms of Multiple Sclerosis include sensory loss, fatigue, cognitive dysfunction, spasticity, depression, optic neuritis, gait ataxia, diplopia, and loss of bladder control. Currently, there is no standardised treatment or cure for Multiple Sclerosis with many strategies focusing on symptoms. Stem cells have emerged as promising approaches for Multiple Sclerosis therapeutics. Clinical trials primarily focus on mesenchymal stem cell-based therapies for Multiple Sclerosis. Furthermore, …

Melittin: A Natural Component Of Honeybee Venom As A Potential Anti-Cancer Therapy, Niamh Donnellan, Anne M. Friel

SURE Journal: Science Undergraduate Research Experience Journal

Cancer is a major cause of death worldwide and while chemotherapy is the main approach there are many negative associations in current treatment procedures. These include lack of selectivity, side effects and drug resistance. The hallmarks of cancer are a fundamental concept which aids the development of new means to treat human cancers through the understanding of the acquisition of these hallmarks from cells.

Melittin is a major peptide component of bee venom which has shown to be efficacious as an anticancer agent in preclinical and animal models. Melittin has many biological functions including pore formation in the phospholipid bilayer …

2023 In Review: Points Of Pride, Reporter Staff

Browse All News

No abstract provided.

Denied, Disrespected, Doubted, And Discarded: Women's Criminal Convictions And Experiences Of Discrimination, Brian Wyant, Holly Harner, Brian Lockwood

Midwest Social Sciences Journal

This study surveyed over 400 incarcerated women in a medium-maximum security prison in the United States to assess their experiences of discrimination due to their criminal conviction. Over 60% of the participants indicated they had been discriminated against due to their felon status. Binary logistic models revealed that discrimination based on prison status can occur both inside and outside of prison but varies by race and length of stay. Similarly, qualitative results showed that during and after their incarceration, these women reported being denied jobs, disrespected and viewed as incapable of changing. Some women even anticipated they would experience discrimination …

Treatment Response Of Gingival Squamous-Cell Carcinoma To Palliative Intent Immunotherapy, Natalia Trehan, Angelina Debbas, Mykaihla Sternick, Jennifer Johnson, James Gates

Department of Medical Oncology Faculty Papers

The use of PD-1 immune checkpoint inhibitor medications has become a common practice in the treatment of recurrent and metastatic head and neck squamous-cell carcinomas. Success in this setting has led to the investigation of their efficacy in locally advanced cases as a part of first-line therapy. In this report, we detail the treatment response to palliative intent immunotherapy of three geriatric patients with mandibular gingival squamous-cell carcinoma who decided against surgical intervention. Patient #1 was treated with pembrolizumab, a PD-1 inhibitor, and displayed complete clinical and radiologic response of the gingival mass after three months of treatment, which is …