Digital Commons Network^™

Volume 18, Issue 1

Medical Muse

No abstract provided.

2015 Great Day Program, State University Of New York At Geneseo

GREAT Day Programs

SUNY Geneseo’s Ninth Annual GREAT Day.

2020 Great Day Program, State University Of New York At Geneseo

GREAT Day Programs

SUNY Geneseo’s Fourteenth Annual GREAT Day.

2021 Great Day Program, State University Of New York At Geneseo

GREAT Day Programs

SUNY Geneseo’s Fifteenth Annual GREAT Day.

Impacts Of Pre-Existing Medical Conditions On Willingness To Pay For Fortified Rice In India, Adithya Sekhar Gummadi

Student Theses and Dissertations

The use of food fortification to combat nutrient deficiencies has garnered popularity as it has proven to be a cost-effective strategy to combat and prevent many diseases and illnesses associated with nutrient deficiencies. This research aimed to examine the willingness to pay (WTP) of Indian consumers for fortified food products predicated on the addition of the nutrients Iron, Zinc, Folic Acid, Vitamin A, and Vitamin B. Additionally, the impact of pre-existing medical conditions on overall willingness to pay is evaluated. This study finds that Indian consumers are willing to pay more for fortified products. A pre-existing medical condition's impact was …

Measuring Deliberate Reflection In Residents: Validation And Psychometric Properties Of A Measurement Tool, Richard H. Blum, Christine L. Mai, John D. Mitchell, Daniel Saddawi-Konefka, Jeffrey B. Cooper, George Shorten, Audrey Dunngalvin

Anesthesiology Articles

PURPOSE: Reflective capacity is "the ability to understand critical analysis of knowledge and experience to achieve deeper meaning." In medicine, there is little provision for post-graduate medical education to teach deliberate reflection. The feasibility, scoring characteristics, reliability, validation, and adaptability of a modified previously validated instrument was examined for its usefulness assessing reflective capacity in residents as a step toward developing interventions for improvement.

METHODS: Third-year residents and fellows from four anesthesia training programs were administered a slightly modified version of the Reflection Evaluation for Learners' Enhanced Competencies Tool (REFLECT) in a prospective, observational study at the end of the …

Targeting Breast Cancer: The Familiar, The Emerging, And The Uncharted Territories, Hamidreza Montazeri Aliabadi, Arthur Manda, Riya Sidgal, Co Chung

Pharmacy Faculty Articles and Research

Breast cancer became the most diagnosed cancer in the world in 2020. Chemotherapy is still the leading clinical strategy in breast cancer treatment, followed by hormone therapy (mostly used in hormone receptor-positive types). However, with our ever-expanding knowledge of signaling pathways in cancer biology, new molecular targets are identified for potential novel molecularly targeted drugs in breast cancer treatment. While this has resulted in the approval of a few molecularly targeted drugs by the FDA (including drugs targeting immune checkpoints), a wide array of signaling pathways seem to be still underexplored. Also, while combinatorial treatments have become common practice in …

This Case Is Out Of Hand: A Non-Infectious Mimic Of Surgical Site Infection Following Routine Surgery, Keaton Reed, Shalmali Mirajkar, Alex Lesiak, Sarah L. Lonowski, Angela L. Hewlett

Posters and Presentations: College of Medicine Students

Background: Pyoderma gangrenosum is a reactive, non-infectious neutrophilic dermatosis that classically presents as a rapidly progressive, erythematous, ulcerative lesion of the skin and soft tissue, sometimes accompanied by necrosis and purulence. It has been reported following routine surgery, and the shared features with skin and soft tissue infection can lead to treatment with antibiotics and further surgical interventions before diagnosis. Case: A 49-year-old woman presented 6 days after a bilateral carpal tunnel release with 3 days of increased pain, erythema, and swelling of the left surgical site with redness tracking up the arm. Empiric antibiotics were started for presumed surgical …

Cytokine Data For Cytokine Profile Assessment From Peruvian Pinniped (Arctocephalus Australis And Otaria Byronia) Plasma, Mykenzee Munaco, Milton Levin, Michael Adkesson, Susana Cárdenas-Alayzad, Dimitrios G. Giarikos, Amy C. Hirons

SECLER Data

Large colonies of two vulnerable, sympatric pinniped species, Peruvian fur seals (Arctocephalus australis Peruvian subpopulation; PFS) and South American sea lions (Otaria byronia; SASL), reside and reproduce in Punta San Juan, Peru (PSJ) where they are exposed to stressors such as contaminants and El Niño Southern Oscillation (ENSO) events. The use of cytokines as immune biomarkers can be indicative of an animal’s health and function by allowing for the assessment of an individual's cytokine balance as type I helper T cells (Th1) or type II helper T cells (Th2) dominant. Utilizing archived pinniped plasma samples from 2009-2019 …

Sustainable Development For Mobile Health Apps Using The Human-Centered Design Process, Qingfan An, Marjorie M Kelley, Audra Hanners, Po-Yin Yen

2020-Current year OA Pubs

Well-documented scientific evidence indicates that mobile health (mHealth) apps can improve the quality of life, relieve symptoms, and restore health for patients. In addition to improving patients' health outcomes, mHealth apps reduce health care use and the cost burdens associated with disease management. Currently, patients and health care providers have a wide variety of choices among commercially available mHealth apps. However, due to the high resource costs and low user adoption of mHealth apps, the cost-benefit relationship remains controversial. When compared to traditional expert-driven approaches, applying human-centered design (HCD) may result in more useable, acceptable, and effective mHealth apps. In …

Antibiotic Resistance Mediated By Escherichia Coli In Kuwait Marine Environment As Revealed Through Genomic Analysis, Ha Al-Sarawi, Nazima Habibi, Saif Uddin, Awadhesh N. Jha, Ma Al-Sarawi, Brett P. Lyons

School of Biological and Marine Sciences

Antibiotic-resistance gene elements (ARGEs) such as antibiotic-resistance genes (ARGs), integrons, and plasmids are key to the spread of antimicrobial resistance (AMR) in marine environments. Kuwait’s marine area is vulnerable to sewage contaminants introduced by numerous storm outlets and indiscriminate waste disposal near recreational beaches. Therefore, it has become a significant public health issue and warrants immediate investigation. Coliforms, especially Gram-negative Escherichia coli, have been regarded as significant indicators of recent fecal pollution and carriers of ARGEs. In this study, we applied a genome-based approach to identify ARGs’ prevalence in E. coli isolated from mollusks and coastal water samples collected in …

Rapid Direct Detection Of Sars-Cov-2 Aerosols In Exhaled Breath At The Point Of Care, Dishit P Ghumra, Nishit Shetty, Kevin R Mcbrearty, Joseph V Puthussery, Benjamin J Sumlin, Woodrow D Gardiner, Brookelyn M Doherty, Jordan P Magrecki, Jane A O'Halloran, Rachel M Presti, Traci L Bricker, Adrianus C M Boon, Carla M Yuede, John R Cirrito, Rajan K Chakrabarty, Et Al.

2020-Current year OA Pubs

Airborne transmission via virus-laden aerosols is a dominant route for the transmission of respiratory diseases, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Direct, non-invasive screening of respiratory virus aerosols in patients has been a long-standing technical challenge. Here, we introduce a point-of-care testing platform that directly detects SARS-CoV-2 aerosols in as little as two exhaled breaths of patients and provides results in under 60 s. It integrates a hand-held breath aerosol collector and a llama-derived, SARS-CoV-2 spike-protein specific nanobody bound to an ultrasensitive micro-immunoelectrode biosensor, which detects the oxidation of tyrosine amino acids present in SARS-CoV-2 viral particles. Laboratory …

Sero-Epidemiology Of Rotavirus Gastroenteritis In Children In Ilorin, Kwara State, Omosigho Omoruyi Pius, Izevbuwa Osazee Ekundayo, Saheed Ibrahim Damilare

Journal of Bioresource Management

Rotavirus is responsible for the most severe dehydrating diarrhea among young children due to gastroenteritis. In this study, we aimed to ascertain the occurrence of childhood gastroenteritis caused by Rotavirus among infants and young children who are younger than 5 years of age in Ilorin, Kwara State and determined the risk factors posing the challenges to be susceptible to diarrhea associated with rotavirus in Ilorin, Kwara State. Diarrhea stool samples were collected from children who passed watery stools, who met predetermined inclusion criteria and who presented at the study hospitals Viz: General Hospital and Specialist Hospital Alagbado and Children Specialist …

Temporal Dynamics Of Genetically Heterogeneous Extended-Spectrum Cephalosporin-Resistant Escherichia Coli Bloodstream Infections, William C Shropshire, Benjamin Strope, Selvalakshmi Selvaraj Anand, Jordan Bremer, Patrick Mcdaneld, Micah M Bhatti, Anthony R Flores, Awdhesh Kalia, Samuel A Shelburne

Faculty, Staff and Student Publications

Extended-spectrum cephalosporin-resistant Escherichia coli (ESC-R-Ec) is an urgent public health threat with sequence type clonal complex 131 (STc131), phylogroup B2 strains being particularly concerning as the dominant cause of ESC-R-Ec infections. To address the paucity of recent ESC-R-Ec molecular epidemiology data in the United States, we used whole-genome sequencing (WGS) to fully characterize a large cohort of invasive ESC-R-Ec at a tertiary care cancer center in Houston, Texas, collected from 2016 to 2020. During the study time frame, there were 1,154 index E. coli bloodstream infections (BSIs) of which 389 (33.7%) were ESC-R-Ec. …

Teachers’ Experiences With Providing Multi-Tiered Student Support For Students With Borderline Intellectual Functioning: A Qualitative Case Study, Teresa Davis Kelso

Doctoral Dissertations and Projects

The purpose of this qualitative case study is to understand the obstacles that rural public school teachers encounter while delivering Multi-Tiered Student Support interventions for students with borderline intellectual functioning. The central question guiding this study was: What are the experiences of rural South Carolina public school teachers tasked with providing Tier III interventions for students with borderline intellectual functioning? The theory guiding this study was Bandera’s self-efficacy theory in that teachers are more effective when they are confident in their ability to use appropriate strategies and materials. The setting for the qualitative study was in a small rural district …

Rebuilding The Secondary School Choral Program After The Covid-19 Pandemic: Tools For Teachers And Administrators And Implications For Future Disruptions To Education, Brandon Allan Stroup

Doctoral Dissertations and Projects

Due to the COVID-19 pandemic, many secondary choral music programs suffered in terms of student involvement, performances, the ability to rehearse, and the overall impact on students’ social and emotional health. Choral music educators have been tasked with implementing strategies to rebuild their programs as schools resumed in-person learning. Utilizing explanatory sequential mixed methods, this study considered surveys of choral music educators and disaggregated student perception data, analyzing the specific needs of students, as well as utilized research surrounding the influence of the COVID-19 pandemic on the social and emotional health of students. Guided by student perception surveys, this mixed …

Improving The Biblical And Spiritual Skills And Knowledge Of Christian Mental Health Counselors At Grace House Counseling Center In Fleming Island, Fl, Larry M. Nichols

Doctoral Dissertations and Projects

Christian licensed mental health counseling at Grace House Counseling Center is a multi-faceted spiritual undertaking that is largely in the purview of lay persons who often work and minister to Christians and non-Christians who live and work in a pluralistic environment. Grace House’s mental health counselors are formally trained through their master’s degree program to provide mental health care, not spiritual or soul care, to clients. While some Grace House counselors have some spiritual training, either from an undergraduate Bible college or through years of self-study, most do not have formal training that links Scripture and spiritual disciplines to various …

Covid-19’S Impact On Dry Bulk Shipping Market : Time Series Analysis Method, Qin Liang

World Maritime University Dissertations

No abstract provided.

Elementary Science Teachers Perceived Self-Efficacy: A Correlational Study Between Teachers With Content And Non-Content Major Degrees In New Jersey, Tiffany R. Baskerville

Doctoral Dissertations and Projects

This predictive, correlational study examines the relationship between undergraduate degree type, methods courses taken in undergraduate school, and the number of years teaching the same grade level and elementary science teachers’ perceived self-efficacy. In this non-experimental study, participants submitted their online responses to the 25-item survey, Science Teaching Efficacy Belief Instrument (STEBI-A), and their demographic information via Google Forms. The researcher used multiple regression to analyze participants’ anonymous responses. In using a multiple linear regression analysis, the researcher examined the results of the STEBI-A to determine how accurately an elementary science teachers’ perceived self-efficacy is predicted by the predictor variable …

Public Health Instructors' Attitudes Regarding Online Instructional Course Design: A Collective Case Study, Meaghan A. Gargin

Doctoral Dissertations and Projects

The purpose of this collective case study was to describe instructors’ attitudes regarding Keller’s personalized system of instruction (PSI) for a sample of online master’s-level public health instructors at an institution of higher education. The central research question was how do public health instructors describe their attitudes regarding personalized system of instruction and online graduate education? The institution selected for this investigation was “University A.” The theory guiding this study was Keller’s personalized system of instruction (PSI), as it features five elements for student-centered course design in higher education learning. The elements include: (a) self-pacing, (b) unit mastery, (c) lectures …

The Experiences Of Tier 3 Early Reading Intervention Providers Three Years After A School Closure: A Phenomenological Study, Sue Ellen Nilena Washington

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the lived experiences of Tier 3 early reading intervention providers at the Urban Independent School District in Texas three years after a school closure. The central research question was, what are the lived experiences of Tier 3 early reading intervention providers in the Urban Independent School district three years after a school closure? Sub-questions explored early reading intervention providers’ beliefs, attitudes, mental states, and actions three years after a school closure. This study was guided by two central theories: the Vygotskian sociocultural theory of human learning and Bandura’s self-efficacy theory. …

English As A Second Language Teachers' Lived Experience Of Transitioning From Remote Learning To The Traditional Classroom Setting: A Phenomenological Study, Shawn Glen Eldot

Doctoral Dissertations and Projects

The purpose of this phenomenological study is to describe the experiences of ESL teachers who transitioned from remote learning back to the traditional classroom setting post-Covid at community colleges in upstate New York. The theory that will be guiding and directing this study will be the constructivist theory. The focus will be on understanding how English as a second language teachers adapt from the distance learning setting implemented during the COVID-19 pandemic back to the brick-and-mortar classroom. In addition, the study will attempt to understand how the behavior of ESL teachers is reflected in the changing teaching environment. The constructivist …

(2021) Addressing Climate Trauma Among Adolescents: Process-Oriented Group Therapy As A Way Forward, Mya Sherman, John A. Dewell

Louisiana Journal of Counseling

Climate change and climate trauma are producing chronic anxiety, grief, despair, and depression, particularly among adolescents and children. Unfortunately, a sincere discussion of both the mental health implications of climate change and conceptualizations of working through climate trauma has been absent from the counseling literature. We address this gap by examining the impact of climate change on mental health, how individuals cope with climate trauma, and the strong potential of process-oriented group therapy to facilitate healing. Finally, we propose a group therapy model to address climate trauma with adolescents.

(2021) Entire Issue, Kellie Camelford, Erin Dugan, Krystal Vaughn

Louisiana Journal of Counseling

No abstract provided.

Cns Tuberculoma In An Immunocompetent Patient: A Case Report Of Multi-Drug Hypersensitivity To Ripe Therapy, Benjamin Huber, Seema Joshi

Infectious Diseases Articles

BACKGROUND: Tuberculosis (TB) is the second leading cause of death due to an infectious disease worldwide (World Health Organization, 2022 [1]). The first line treatment of TB involves the concurrent use of four drugs: rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE). Given the rising threat of multidrug resistant TB, it is crucial to understand how TB can be treated when first line treatment is not an option.

CASE PRESENTATION: We report a rare case of multi-drug hypersensitivity to RIPE therapy in an immunocompetent patient with an unusual presentation of CNS tuberculoma. The patient presented to an outside hospital four months prior …

About Premedical Programs At Ud, Udayton

Pre-Health Resource Center Campus Communications

No abstract provided.

Prevalence And Trends Of Advanced Hiv Disease Among Antiretroviral Therapy-Naïve And Antiretroviral Therapy-Experienced Patients In South Africa Between 2010-2021: A Systematic Review And Meta-Analysis, Marcel K Kitenge, Geoffrey Fatti, Ingrid Eshun-Wilson, Omololu Aluko, Peter Nyasulu

2020-Current year OA Pubs

BACKGROUND: Despite the significant progress made in South Africa in getting millions of individuals living with HIV into care, many patients still present or re-enter care with Advanced HIV Disease (AHD). We aimed to estimate the prevalence of AHD among ART-naive and ART-experienced patients in South Africa using studies published between January 2010 and May 2022.

METHODS: We searched for relevant data on PubMed, CINAHL, Scopus and other sources, with a geographical filters limited to South Africa, up to May 31, 2022. Two reviewers conducted all screening, eligibility assessment, data extraction, and critical appraisal. We synthesized the data using the …

International Epidemiology Of Carbapenemase-Producing Escherichia Coli, Angelique E Boutzoukas, Lauren Komarow, Liang Chen, Blake Hanson, Souha S Kanj, Zhengyin Liu, Soraya Salcedo Mendoza, Karen Ordoñez, Minggui Wang, David L Paterson, Scott Evans, Lizhao Ge, Abhigya Giri, Carol Hill, Keri Baum, Robert A Bonomo, Barry Kreiswirth, Robin Patel, Cesar A Arias, Henry F Chambers, Vance G Fowler, David Van Duin

Faculty, Staff and Student Publications

BACKGROUND: Carbapenemase-producing (CP) Escherichia coli (CP-Ec) are a global public health threat. We aimed to describe the clinical and molecular epidemiology and outcomes of patients from several countries with CP-Ec isolates obtained from a prospective cohort.

METHODS: Patients with CP-Ec were enrolled from 26 hospitals in 6 countries. Clinical data were collected, and isolates underwent whole-genome sequencing. Clinical and molecular features and outcomes associated with isolates with or without metallo-β-lactamases (MBLs) were compared. The primary outcome was desirability of outcome ranking (DOOR) at 30 days after the index culture.

RESULTS: Of the 114 CP-Ec isolates in Consortium on resistance against …

Metapopulation Dynamics Of Sars-Cov-2 Transmission In A Small-Scale Amazonian Society, Thomas Kraft, Edmond Seabright, Sarah Alami, Samuel M. Jenness, Paul L. Hooper, Bret Beheim, Helen Davis, Daniel K. Cummings, Daniel Eid Rodriguez, Maguin Gutierrez Cayuba, Emily J. Miner, Xavier De Lamballerie, Lucia Inchauste, Stéphane Priet, Benjamin Trumble, Jonathan Stieglitz, Hillard Kaplan, Michael Gurven

ESI Publications

The severity of infectious disease outbreaks is governed by patterns of human contact, which vary by geography, social organization, mobility, access to technology and healthcare, economic development, and culture. Whereas globalized societies and urban centers exhibit characteristics that can heighten vulnerability to pandemics, small-scale subsistence societies occupying remote, rural areas may be buffered. Accordingly, voluntary collective isolation has been proposed as one strategy to mitigate the impacts of COVID-19 and other pandemics on small-scale Indigenous populations with minimal access to healthcare infrastructure. To assess the vulnerability of such populations and the viability of interventions such as voluntary collective isolation, we …

Exploration Of A Potential Desirability Of Outcome Ranking Endpoint For Complicated Intra-Abdominal Infections Using 9 Registrational Trials For Antibacterial Drugs, Tori Kinamon, Ramya Gopinath, Ursula Waack, Mark Needles, Daniel Rubin, Deborah Collyar, Sarah B Doernberg, Scott Evans, Toshimitsu Hamasaki, Thomas L Holland, Jessica Howard-Anderson, Henry Chambers, Vance G Fowler, Sumati Nambiar, Peter Kim, Helen W Boucher

Faculty, Staff and Student Publications

BACKGROUND: Desirability of outcome ranking (DOOR) is a novel approach to clinical trial design that incorporates safety and efficacy assessments into an ordinal ranking system to evaluate overall outcomes of clinical trial participants. Here, we derived and applied a disease-specific DOOR endpoint to registrational trials for complicated intra-abdominal infection (cIAI).

METHODS: Initially, we applied an a priori DOOR prototype to electronic patient-level data from 9 phase 3 noninferiority trials for cIAI submitted to the US Food and Drug Administration between 2005 and 2019. We derived a cIAI-specific DOOR endpoint based on clinically meaningful events that trial participants experienced. Next, we …