Digital Commons Network^™

Risk Burden Of Heat-Related Morbidity Due To Urban Heat Island Effect In Tamalanrea District, Makassar, Angelia Khairunnisa, Ihsan Ihsan, Marly Patandianan

Media Kesehatan Masyarakat Indonesia

One of the problems in the urban environment is the rise in land surface temperature and heat buildup (Urban Heat Island) around built-up areas. People living in UHI areas will experience an increased risk of health burdens. Therefore, early identification for disaster mitigation is needed to achieve a sustainable city. This study aims to provide an overview of the risk of the spread of heat-related diseases based on the relative risk value in Tamalanrea District. This study considers the relationship between Land Surface Temperature (LST) values in 2019, 2020, and 2021 with the incidence of heat-related diseases obtained from the …

Investigating Power In Golding's 'Lord Of The Flies': A Stylistic Consideration, Salam Abbas Mahmood, Zamaan Tawfeeq Abdul-Hassan

Uruk Journal of Human Sciences

"Lord of the files" is considered one of the famous fictions that treated the topics of psychology, power, and social relations. The current study, by adopting an aspect of Halliday's "Systemic Functional Linguistics" theory, investigates the ideological conception of different groups in relation to the notions of power, powerlessness, and fear. This is done by showing how power is represented in what each group feels and thinks towards the other. The analysis contributes to the character’s full understanding. The study also includes an analysis procedure namely the verb process elements of analysis, which the characters simplify about strength (power) and …

Mir-142: A Master Regulator In Hematological Malignancies And Therapeutic Opportunities, Wilson Huang, Doru Paul, George A Calin, Recep Bayraktar

Faculty, Staff and Student Publications

MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently associated with the onset and progression of human cancers. miR-142, an ultra-conserved miRNA with both active -3p and -5p mature strands and wide-ranging physiological targets, has been the subject of countless studies over the years. Due to its preferential expression in hematopoietic cells, miR-142 has been found to be associated with numerous types of lymphomas and leukemias. This review elucidates the multifaceted role of miR-142 in human physiology, its influence on hematopoiesis and hematopoietic cells, and its intriguing involvement in exosome-mediated miR-142 transport. Moreover, we offer a comprehensive …

The Development And Validation Of Novel Imaging Biomarkers For Uterine Contraction, Cervix And Placenta In Pregnancy, Wenjie Wu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Annually, nearly half a million neonates in the United States and 15 million globally are born preterm, defined as prior to 37 completed weeks of gestation. These births present elevated risks of neonatal mortality and long-term neurological deficits. The predominant obstetric precursors of preterm birth (PTB) include spontaneous preterm labor (45%), medically-indicated deliveries (30%), and preterm premature rupture of membranes (PPROM, 25%). Each precursor is associated with distinct physiological or structural alterations such as uterine contractions, placental dysfunction, or cervical insufficiency. Current methodologies for monitoring uterine contractions, such as intrauterine pressure catheters and electrohysterography, possess limitations in spatial resolution, coverage, …

A Patterned Human Primitive Heart Organoid Model Generated By Pluripotent Stem Cell Self-Organization, Brett Volmert, Chao Zhou, Et Al.

2020-Current year OA Pubs

Pluripotent stem cell-derived organoids can recapitulate significant features of organ development in vitro. We hypothesized that creating human heart organoids by mimicking aspects of in utero gestation (e.g., addition of metabolic and hormonal factors) would lead to higher physiological and anatomical relevance. We find that heart organoids produced using this self-organization-driven developmental induction strategy are remarkably similar transcriptionally and morphologically to age-matched human embryonic hearts. We also show that they recapitulate several aspects of cardiac development, including large atrial and ventricular chambers, proepicardial organ formation, and retinoic acid-mediated anterior-posterior patterning, mimicking the developmental processes found in the post-heart tube stage …

Twitch Chat Advertising: How Live Chat Valence Affects Consumer Advertising Perceptions, Austin W. Camper

Theses and Dissertations

The streaming platform Twitch.tv, is a popular video streaming website where users can watch, communicate, and chat with streamers and other viewers live. Twitch and other live streaming websites typically offer viewers a chat window where the viewer can chat (in real-time) with the streamer and other viewers who are currently watching the stream. Research in live streaming platforms like Twitch and the effects of their various features are novel. The purpose of this study is to analyze how the sentiment of a live chat (positive or negative) and the stated or not stated disclosure of an advertisement posted in …

Summit Report: The Future And Ethics Of Uncrewed And Autonomous Warfare, Arman Mahmoudian

GNSI Summit Reports

On September 27-28, 2023, the Global and National Security Institute (GNSI) held the 8th Great Power Competition Conference titled “The Future and Ethics of Uncrewed and Autonomous Warfare” at the University of South Florida’s Tampa campus. As a featured event of the 2nd GNSI Tampa Summit, the conference included three major panels: “Foreign Defense Partnership in a Global Competitive Market,” “Ethical Use of Uncrewed Warfare,” and “Future of Uncrewed Systems: The Benefits and Dangers of Advancing Technology.” These panels brought together experts to discuss the evolving role of uncrewed and autonomous systems in warfare, their ethical implications, and the impact …

Benefits Of Sharing Neurophysiology Data From The Brain Initiative Research Opportunities In Humans Consortium, Vasiliki Rahimzadeh, Kathryn Maxson Jones, Mary A Majumder, Michael J Kahana, Ueli Rutishauser, Ziv M Williams, Sydney S Cash, Angelique C Paulk, Jie Zheng, Michael S Beauchamp, Jennifer L Collinger, Nader Pouratian, Amy L Mcguire, Sameer A Sheth

Center for Medical Ethics and Health Policy Staff Publications

Sharing human brain data can yield scientific benefits, but because of various disincentives, only a fraction of these data is currently shared. We profile three successful data-sharing experiences from the NIH BRAIN Initiative Research Opportunities in Humans (ROH) Consortium and demonstrate benefits to data producers and to users.

Strategies Managers Use To Motivate Millennials, Talena Lynn Edwards

Walden Dissertations and Doctoral Studies

No abstract provided.

The Echo: December 4, 2023, Taylor University

2023-2024 (Volume 111)

No abstract provided.

Chapman Early Music Ensemble, Chapman Early Music Ensemble

Printed Performance Programs (PDF Format)

No abstract provided.

Perturbation Based Decomposition For Motor Unit Number Estimation, Anna T. Pham

Master's Theses

Motor unit number estimation (MUNE) is of clinical significance because information associated with motor unit populations and the loss of motor units over time are crucial to the diagnosis and monitoring of neuromuscular disorders. The responses of individual motor units can be extracted through incremental stimulation of a muscle group of interest and further analyzed through various methods to compute the MUNE. In this work, the utility of the perturbation-based decomposition by Szlavik will be investigated for this application and compared to the original MUNE approach developed by McComas. Successful decomposition may suggest an alternative method for motor unit number …

Investigating The Effects Of Subchronic Dietary Zinc Supplementation On Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease., Oluwanifemi Esther Bolatimi

Electronic Theses and Dissertations

Zinc deficiency is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). Previous studies show zinc supplementation improves steatosis, but its therapeutic effects in established MASLD remain unclear. We developed a model to characterize the effects of zinc supplementation on high-fat diet (HFD) induced MASLD and hypothesized established MASLD would be attenuated. Mice were fed control diet or HFD for 12 weeks and then grouped into normal or zinc-supplemented diets for 8 additional weeks. At euthanasia, plasma and liver tissues were collected for phenotypic analysis. Twelve weeks of HFD altered glucose clearance and body composition. Eight weeks of subsequent zinc supplementation …

Pulmonary & Critical Care Insider: Issue 4, Bharat Bajantri Md, Sarah Ellsworth-Hoffman Mls

Critical Care & Pulmonary

Pulmonary & Critical Care Insider Issue 4

Compiled by Bharat Bajantri, MD, and librarian Sarah Ellsworth, MLS for the clinicians of the Pulmonary and Critical Care team of Parkview.

The goal of this newsletter is to give a brief summary of the most pertinent articles to everyday practice and an attempt to keep up with literature as best as possible. Newsletters go out every 1-2 months.

Summaries/Topics in this issue:

• Inside Medicine- Ozempic

• Inhaled Amikacin for VAP (AMIKINHAL Trial)

• 2023 GOLD Guidelines for COPD

• SAGA of Antibiotics in the ICU

• The MANDALA trial

• The DENALI trial

• RESCUE IHCA – Not …

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New Insights In The Mechanisms Of Weight-Loss Maintenance: Summary From A Pennington Symposium, Emily W. Flanagan, Redin Spann, Sarah E. Berry, Hans Rudolf Berthoud, Stephanie Broyles, Gary D. Foster, Jonathan Krakoff, Ruth J.F. Loos, Michael R. Lowe, Danielle M. Ostendorf, Tiffany M. Powell-Wiley, Leanne M. Redman, Michael Rosenbaum, Philip R. Schauer, Randy J. Seeley, Boyd A. Swinburn, Kevin Hall, Eric Ravussin

Division of Basic Science Faculty Publications

Obesity is a chronic disease that affects more than 650 million adults worldwide. Obesity not only is a significant health concern on its own, but predisposes to cardiometabolic comorbidities, including coronary heart disease, dyslipidemia, hypertension, type 2 diabetes, and some cancers. Lifestyle interventions effectively promote weight loss of 5% to 10%, and pharmacological and surgical interventions even more, with some novel approved drugs inducing up to an average of 25% weight loss. Yet, maintaining weight loss over the long-term remains extremely challenging, and subsequent weight gain is typical. The mechanisms underlying weight regain remain to be fully elucidated. The purpose …

Body Shape Perception In Men And Women Without Obesity During Caloric Restriction: A Secondary Analysis From The Calerie Study, Maci M. Jacobson, Alexis M. Gardner, Camilla E. Handley, Michael W. Smith, William F. Christensen, Chad R. Hancock, Paule V. Joseph, Michael J. Larson, Corby K. Martin, James D. Lecheminant

Clinical Research Faculty Publications

Objective: To examine body shape perception in 218 adults without obesity or history of eating disorders during caloric restriction (CR). Methods: Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) is a 2-year, randomized clinical trial using a 2:1 assignment (CR, 25% reduction in calories; Control, typical diet). For this secondary analysis, we examined perceived body shape using the Body Shape Questionnaire (BSQ). Analyses of BSQ scores are reported by group, over time, by sex, and by BMI. Data for body fat percentage, symptoms of depression, food cravings, maximal oxygen consumption, and stress were analyzed for their association …

Cancer Risk In Human Spaceflight And Directions For Space Nursing: A Rapid Scoping Review, Brighton Blaze Krejci

Honors Capstone Projects and Theses

No abstract provided.

Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian

Biomedical Engineering: Graduate Reports and Projects

As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …

(R2055) Magnetic Effects On Unsteady Non-Newtonian Blood Flow Through A Tapered And Overlapping Stenotic Artery, Abiodun J. Babatunde, Moses S. Dada

Applications and Applied Mathematics: An International Journal (AAM)

This study aims to investigating the effect of magnetic field and porosity on non-Newtonian flow of blood through a tapered, and overlapping stenosed artery. The Casson fluid model represents the rheological character of blood. A tapered and overlapping stenosed artery influences the hemodynamic behavior of the blood flow. The problem is solved by using analytical techniques with the help of boundary conditions, and results are displayed graphically for different flow characteristics like pressure drop, shear stress, velocity profile and stream function. It is realized that rises in Darcy number and Womersley number accelerates the velocity profile and reduces the radial …

Optimized Indoor Temperature In Office Buildings Through Personalized Thermal Comfort Modeling, Raviteja Patchava

UNLV Theses, Dissertations, Professional Papers, and Capstones

Building occupants experience varying thermal comforts at static indoor set-point temperatures due to variances in preferences, needs, and activities, both within and among individuals. Despite advancement in smart building control systems, many building occupants remain dissatisfied with indoor temperatures. This study developed and created an optimization model to predict the optimized indoor temperature preferences in multiple-occupancy settings. To achieve this, personalized thermal comfort models for each occupant in a multiple occupancy space were developed. The personal comfort models serve as the foundation for predicting their individual thermal preference and developing indoor temperature optimization model. When predicting the individual thermal preference, …

Assessing Virtual Versus In-Person Experiential Learning And Medical High-Fidelity Simulation In Medical Student Pediatric Clerkship Training, Andrew Mitchell Berry

Electronic Theses and Dissertations

Simulation and experiential training have been incorporated into medical school training for decades. The utilization of medical simulations has become an invaluable tool in healthcare education and training. However, circumstances such as limited resources, geographical constraints, or global health crises may hinder the feasibility of conducting in-person medical simulations. In these scenarios, virtual medical simulations emerge as a compelling alternative. While there are many ways to accomplish experiential-based learning, many faculty and students feel Socratic learning styles provide the best learning experience.

As medical students had just finished a predominantly virtual preclinical year due to the COVID-19 pandemic, the research …

Rabrs For Use In Biologically Enhanced Precipitation Of Struvite In Anaerobic Digester Effluent (Municipal Wastewater), Parker R. Goldsberry

All Graduate Theses and Dissertations, Fall 2023 to Present

Rotating Algae Biofilm Reactor (RABR) technology has been researched in studies over the past decade directed at nutrient management for water resource recovery facilities (WRRFs). This study investigated the growth of slow-release fertilizer crystals, referred to as struvite, in the algae biofilms of Rotating Algae Biofilm Reactors (RABRs) at the Central Valley Water Reclamation Facility, the largest water resource recovery facility in the State of Utah. RABRs used anaerobic digester (AD) filtrate as their nutrient source. AD effluent is high in nutrients like nitrogen and phosphorus. The levels of both phosphorus and nitrogen (in the form of ammonia) are regulated …

The Effects Of An Equine Riding Simulator As An Objective Feedback Modality On Learning Outcomes For Rider Competency On Performance Skills In Equestrian Riding Fundamentals, Kelli Munns

All Graduate Theses and Dissertations, Fall 2023 to Present

This study examined the effects of different feedback modalities provided during simulated-based practice on performance and perceptions. In addition, the research also addressed the relationship between participants' feedback literacy, perceptions, and improvement scores. The purpose of this research was motivated by the emerging equine simulation technology that provides feedback on movement and coordination during complex motor skill acquisition. Selecting an effective feedback approach for simulation-based practice in motor skill learning is contingent on the complexity of the performance skill and the learner's experience. However, the learner's feedback literacy can result in contradictory performance and perceptions despite the feedback approach experienced. …

The Physiological Effects Of Acute And Ramp Hypoxic Exposure During Simulated Flight Tasks, Jasmin Renee Jenkins

Open Access Theses & Dissertations

The purpose of the present study was to examine the effects of hypoxia at simulated altitudes of FiO2 15.4% (8000’ equivalent), FiO2 13.2% (12,000’ equivalent), and a Ramp Hypoxic exposure on perceived workload, cardiovascular activity, electrodermal activity, oximetry, and flight simulator performance. A total of 17 participants (10 female & 7 males; mean ± SEM, age 24.82±1.6 yrs, BMI 25.87±1.0 who were apparently healthy, asymptomatic, and physically active performed 3 flight tasks using a video game head-mounted display (HMD) flight simulator while exposed to simulated altitudes of Normoxia, FiO2 15.4%, FiO2 13.2% and a Ramp Hypoxic Exposure (breathing at 8,000 …

An In Vitro Platform To Characterize Myocardial Wound Remodeling, Jonathan Heywood

All Dissertations

Heart Failure, sometimes called Congestive Heart Failure, is a collection of pathological disruptions in which the heart is unable to pump blood properly. It affects over 6 million people in the United States, with the cost-per-patient at approximately $30,000 and the total cost estimated to be $160 billion by 2030. There is no single cause of heart failure, as it can manifest as a varying array of diseases, disorders, and syndromes. However, many of these underlying diseases result specifically from dysregulation of mechanically active cells called cardiac fibroblasts, which play a critical role in the remodeling of the extracellular matrix …

Estimating The Chemical Composition Of Secondary Compounds Of Iraqi Wild Agaricus Bellaniae Characterized Morphologically And Genetically, Ziena M. Abdul-Qader, Rukiabaa A. Chechan, Sudad K.M. Al-Taweel

Baghdad Science Journal

This study, which is considered the first of its kind in the world and the Arab homeland, was carried out in the laboratory of mushroom production belonging to the Medicinal Plant Unit/ College Of Agricultural Engineering Sciences/ University of Baghdad during the period from July 21, 2016, to December 30, 2018, aiming to isolate and purify the mycelium of the wild isolation in addition to the genetic and morphological identification of the mushroom Agaricus bellaniae. The obtained pure isolation was tagged in the American National Center for Biotechnology Information (NCBI) with symbol MF987843.1, thus Iraq would be the second country …

Development Of Thermosensitive Hydrogel Of Amphotericin-B And Lactoferrin Combination-Loaded Plga-Peg-Pei Nanoparticles For Potential Eradication Of Ocular Fungal Infections, Sammar Fathy Elhabal, Shrouk A Ghaffar, Raghda Hager, Nahla A Elzohairy, Mohamed Mansour Khalifa, Passant M Mohie, Rania A Gad, Nasreen N Omar, Mohammed H Elkomy, Mohammad Ahmad Khasawneh, Nashwa Abdelaal

Faculty, Staff and Students Publications

The most prevalent conditions among ocular surgery and COVID−19 patients are fungal eye infections, which may cause inflammation and dry eye, and may cause ocular morbidity. Amphotericin-B eye drops are commonly used in the treatment of ocular fungal infections. Lactoferrin is an iron-binding glycoprotein with broad-spectrum antimicrobial activity and is used for the treatment of dry eye, conjunctivitis, and ocular inflammation. However, poor aqueous stability and excessive nasolacrimal duct draining impede these agens' efficiency. The aim of this study was to examine the effect of Amphotericin-B, as an antifungal against Candida albicans, Fusarium, and Aspergillus flavus, and Lactoferrin, …

Development Of Canagliflozin Nanocrystals Sublingual Tablets In The Presence Of Sodium Caprate Permeability Enhancer: Formulation Optimization, Characterization, Sammar Fathy Elhabal, Mohamed A El-Nabarawi, Nashwa Abdelaal, Mohamed Fathi Mohamed Elrefai, Shrouk A Ghaffar, Mohamed Mansour Khalifa, Passant M Mohie, Dania S Waggas, Ahmed Mohsen Elsaid Hamdan, Samar Zuhair Alshawwa, Essa M Saied, Nahla A Elzohairy, Tayseer Elnawawy, Rania A Gad, Nehal Elfar, Hanaa Mohammed, Mohammad Ahmad Khasawneh

Faculty, Staff and Students Publications

Canagliflozin (CFZ) is a sodium-glucose cotransporter-2 inhibitor (SGLT2) that lowers albuminuria in type-2 diabetic patients, cardiovascular, kidney, and liver disease. CFZ is classified as class IV in the Biopharmaceutical Classification System (BCS) and is characterized by low permeability, solubility, and bioavailability, most likely attributed to hepatic first-pass metabolism. Nanocrystal-based sublingual formulations were developed in the presence of sodium caprate, as a wetting agent, and as a permeability enhancer. This formulation is suitable for children and adults and could enhance solubility, permeability, and avoid enterohepatic circulation due to absorption through the sublingual mucosa. In the present study, formulations containing various surfactants …

A Novel Computing Scheme Based On Pattern Matching For Identification Of Nephron Loss And Chronic Kidney Disease Stage, Rehan Ahmad, Basant Mohanty

Turkish Journal of Electrical Engineering and Computer Sciences

Nephrons are the basic filtering units of the kidneys. Progression of chronic kidney disease (CKD) destroys nephrons permanently. Although there are many computing schemes suggested in recent years to identify CKD stages, no computing method has been suggested for identifying the nephron loss within kidney regions during CKD progression. In this paper, a novel pattern matching-based computation scheme is proposed to detect nephron loss in the kidney regions during CKD progression. We consider image registration (IR) with different transforms and a structural similarity index algorithm (SSIM) to match patterns of ultrasound images of kidney regions to identify the nephron loss. …

Building An Electronic Educational Program Based On The Schuman Investigative Model In The Developed Geology Course And Investigating Its Impact On Developing Critical Thinking Skills For 10th-Grade Students In Jordan, Eyad Bani Domi, Hussein Baara

Jordan Journal of Applied Science-Humanities Series

This study aimed to build an electronic educational program based on the Schuman investigative model in the revised Geology course and to investigate its impact on developing critical thinking skills among 10th-grade students in Jordan. The study sample consisted of 69 tenth-grade students, randomly divided into two groups. One group was randomly selected to represent the experimental group, which comprised 33 students who studied using the electronic educational program based on the Schuman investigative model. The second group served as the control group and consisted of 36 students who studied in the usual way. The study tools included the electronic …