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2023

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Investigating The Critical Literacy Practices Of Adult Learners: A Case Study Of Four Leveled Reading Courses At A Community College, Anna Fontaine Dec 2023

Investigating The Critical Literacy Practices Of Adult Learners: A Case Study Of Four Leveled Reading Courses At A Community College, Anna Fontaine

Dissertations

This study investigates the critical literacy practices of adult learners at a community college. Student participants were selected from four different leveled reading courses. In this study, four guiding questions were adopted from Klenner and Sandretto (2011): (1) How do students make personal connections to text?; (2) In what ways do students identify multiple points of view in the text?; (3) In what ways do students identify where people in the text and included or excluded from social situations?; (4) In what ways do students discuss the influences the text has had on their views of society? These four questions …


The Effects Of Mindfulness And Exercise On Symptoms Of Parkinson’S Disease: A Systematic Review, Collin Tyler Garner Dec 2023

The Effects Of Mindfulness And Exercise On Symptoms Of Parkinson’S Disease: A Systematic Review, Collin Tyler Garner

Dissertations

Parkinson’s Disease (PD) is the second most common neurodegenerative disease affecting which affects motor control, emotional regulation, cognition, and sleep through degradation of dopaminergic neurons. As of 2019, PD affects approximately 8.5 million individuals worldwide, with prevalence estimated to increase to between 8.7 and 9.3 million by 2030. The primary therapeutic approach to PD management is pharmaceutical, relying on dopamine replacement therapy. However, recent research has identified promising complementary therapies such as exercise and mindfulness training.

This review was conducted to compile and present evidence related to the efficacy of exercise, mindfulness, and combined exercise and mindfulness protocols as complementary …


Stigma And Mental Health In Miami, Fl, Nicholas Pujol Dec 2023

Stigma And Mental Health In Miami, Fl, Nicholas Pujol

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Goal Statement: To increase awareness of the issues that people with serious mental illness face in order to reduce stigma and increase treatment participation rates. Significant Findings: Serious mental illness is a serious issue that is increasing every year. In Florida as of 2021 there are an estimated 725,239 people that have a serious mental illness (Florida Department of Health, n.d). Over the last 10 years that has been an upward trend. With the increase in population there too needs to be an increase in services in order to meet the needs of this population. Stigma against this population can …


An Island Of Sanity During Covid-19 Pandemic: Does Pet Attachment Support Buffer Employees' Stress Due To Job Insecurity?, Min Maggie Wan, Thomas K. Kelemen, Yejun Zhang, Samuel H. Matthews Dec 2023

An Island Of Sanity During Covid-19 Pandemic: Does Pet Attachment Support Buffer Employees' Stress Due To Job Insecurity?, Min Maggie Wan, Thomas K. Kelemen, Yejun Zhang, Samuel H. Matthews

Management Faculty Publications

Drawing on the transactional theory of stress, the current study investigates whether employee job insecurity triggers employee behavioral strain reactions (i.e., alcohol use, marijuana use, and cigarette use) and psychological strain reactions (i.e., emotional exhaustion and depression) through stress during the COVID-19 pandemic. In addition, we integrate social support theory and expect the moderating role of pet attachment support in the above relationships. By collecting two-wave data from 187 employees with pets in the United States, we found that during the COVID-19 pandemic, stress mediated the relationships between job insecurity and predicted behavioral and psychological reactions. Moreover, pet attachment support …


Water Main Break Rates In The Usa And Canada: A Comprehensive Study, Steven L. Barfuss Dec 2023

Water Main Break Rates In The Usa And Canada: A Comprehensive Study, Steven L. Barfuss

Reports

Deteriorating Infrastructure

Municipalities and the people they serve depend on pipe networks that provide safe drinking water. This piping is underground, out of sight, and often neglected.

Overall assessment of water infrastructure condition is not good. Using the US as an example:

  • In 2009, the American Society of Civil Engineers (ASCE) issued a US report card and gave a D- to drinking water infrastructure.
  • In 2017, the grade improved to a D.
  • In 2021, the grade was raised to a C-, better but still not good.
  • Utilities are currently losing 11% of their water to leakage.
  • Pipe life estimates of …


Trash, Fragments, And Breaking Things: Toward A Grotesque Cripistemology For Disabled Life Writing, Michelle Anne Lloyd Dec 2023

Trash, Fragments, And Breaking Things: Toward A Grotesque Cripistemology For Disabled Life Writing, Michelle Anne Lloyd

All Dissertations

Despite the boom of memoirs of mental health post-1997 and the first advertisements for Prozac, most of them follow the same formula and come from the same places of privilege. This privilege is evident in the author bios on the books themselves and the careers of the writers. The popularity of these books within both abled and disabled realms has therefore created a script that those with mental illnesses are expected to abide by. Following in the example of Margaret Price, Katie Rose Guest Pryal, Merri Lisa Johnson, and others, I resituate mental illness as mental disability and place it …


Biochemical And Kinetic Analysis Of Phosphofructokinase In The Eukaryotic Human Pathogen Entamoeba Histolytica, Jin Cho Dec 2023

Biochemical And Kinetic Analysis Of Phosphofructokinase In The Eukaryotic Human Pathogen Entamoeba Histolytica, Jin Cho

All Dissertations

Entamoeba histolytica is a water- and food-borne intestinal parasite that causes amoebiasis and liver abscess in ~100 million people each year leading to ~100,000 deaths. This amitochondriate parasite lacks many metabolic pathways including the tricarboxylic acid cycle and oxidative phosphorylation, and cannot synthesize purines, pyrimidines, or most amino acids. As a result, E. histolytica is presumed to rely on its modified pyrophosphate (PPi)-dependent glycolytic pathway for ATP production during growth on glucose. This pathway relies on a PPi-dependent rather than ATP-dependent phosphofructokinase (PFK) and thus has a net production of three ATP per glucose. However, in …


Interpretable Mechanistic And Machine Learning Models For Pre-Dicting Cardiac Remodeling From Biochemical And Biomechanical Features, Anamul Haque Dec 2023

Interpretable Mechanistic And Machine Learning Models For Pre-Dicting Cardiac Remodeling From Biochemical And Biomechanical Features, Anamul Haque

All Dissertations

Biochemical and biomechanical signals drive cardiac remodeling, resulting in altered heart physiology and the precursor for several cardiac diseases, the leading cause of death for most racial groups in the USA. Reversing cardiac remodeling requires medication and device-assisted treatment such as Cardiac Resynchronization Therapy (CRT), but current interventions produce highly variable responses from patient to patient. Mechanistic modeling and Machine learning (ML) approaches have the functionality to aid diagnosis and therapy selection using various input features. Moreover, 'Interpretable' machine learning methods have helped make machine learning models fairer and more suited for clinical application. The overarching objective of this doctoral …


The Power Of Play: The Role Of Children’S Museums In Kindergarten Readiness, Catie Davis Dec 2023

The Power Of Play: The Role Of Children’S Museums In Kindergarten Readiness, Catie Davis

All Dissertations

This study explores the transformative potential of play in preparing young children for Kindergarten, focusing on the intersection of children's museums, caregiver interactions, and school readiness. The study, conducted over an eight-week Pop-Up Classroom program at The Flowerfield Children's Museum, included 52 participants, primarily from low-income backgrounds. Through a mixed-methods approach, including participant observations and caregiver surveys, the research aimed to answer the fundamental question: What is the role of play in preparing children for Kindergarten?

Two significant findings emerged. Firstly, the study illuminated the pivotal role of play in nurturing social-emotional development and communication skills among children. Structured observations …


A Digital Triplet For Utilizing Offline Environments To Train Condition Monitoring Systems For Rolling Element Bearings, Ethan Wescoat Dec 2023

A Digital Triplet For Utilizing Offline Environments To Train Condition Monitoring Systems For Rolling Element Bearings, Ethan Wescoat

All Dissertations

Manufacturing competitiveness is related to making a quality product while incurring the lowest costs. Unexpected downtime caused by equipment failure negatively impacts manufacturing competitiveness due to the ensuing defects and delays caused by the downtime. Manufacturers have adopted condition monitoring (CM) techniques to reduce unexpected downtime to augment maintenance strategies. The CM adoption has transitioned maintenance from Breakdown Maintenance (BM) to Condition-Based Maintenance (CbM) to anticipate impending failures and provide maintenance actions before equipment failure. CbM is the umbrella term for maintenance strategies that use condition monitoring techniques such as Preventive Maintenance (PM) and Predictive Maintenance (PdM). Preventive Maintenance involves …


An Evaluation Of Clemson University’S Cooperative Extension Services Online Learning Programs And Framework For Program Development And Evaluation, Christina Leard Dec 2023

An Evaluation Of Clemson University’S Cooperative Extension Services Online Learning Programs And Framework For Program Development And Evaluation, Christina Leard

All Dissertations

The COVID-19 pandemic brought online learning to the forefront with the need to define online learning with best practices. Clemson University Extension conducted a retrospective observational study compiling survey data from virtual extension agents and supervisor’s conducting online programs. A literature review analyzed terminology for online learning to obtain a standardized definition to define online learning for Clemson Extension Services programs; evaluate and identify through literature strengths, weaknesses, opportunities, and challenges (SWOC) of on-line learning; determine and identify online learning competencies for instructors, assessment and evaluation; and analyze and evaluate response data from virtual extension agents delivering online programs in …


Exploring Modalities Of Productivity And Critical Quality Attributes In Fed-Batch Chinese Hamster Ovary Cell Cultures, Stephanie Klaubert Dec 2023

Exploring Modalities Of Productivity And Critical Quality Attributes In Fed-Batch Chinese Hamster Ovary Cell Cultures, Stephanie Klaubert

All Dissertations

Chinese hamster ovary (CHO) cells are among the most commonly used mammalian cell lines for the production of recombinant therapeutic proteins due to ease of culturing and humanlike post-translational modification capabilities. However, when compared to microbial systems, CHO cell line growth and productivity is relatively low. As the demand for monoclonal antibody (mAb) treatments continues to rise, it is critical to explore modalities for improved growth and productivity in CHO cell cultures, with the goal of increased protein concentrations and maintained product quality. Though some mechanisms for improved productivity, including temperature and cell culture media formulations, are relatively well understood; …


Towards Enabling Usable Batteryless Wearables, Arwa Alsubhi Dec 2023

Towards Enabling Usable Batteryless Wearables, Arwa Alsubhi

All Dissertations

Wearable devices have become ubiquitous in modern technology, providing a convenient way for a large number of users to monitor their health and track their daily activities. However, despite their numerous benefits, wearable devices are not without their challenges. One of the most significant issues is the need to recharge their batteries, which can disrupt users’ daily routines and might result in the discontinuation of device use.

Replacing batteries with capacitors and charging them using the available harvested energy from the surrounding environment (e.g., kinetic, thermal, or solar energy) eliminates the burden of recharging or replacing batteries, resulting in convenient, …


Engineering Next-Generation Cardiovascular Therapies, Ryan Walker Barrs Dec 2023

Engineering Next-Generation Cardiovascular Therapies, Ryan Walker Barrs

All Dissertations

Cardiovascular diseases are the leading cause of death worldwide. Heart disease, in particular, accounted for 1 in every 5 deaths in the United States in 2021, representing a substantial public health burden that will require more effective treatment options to alleviate. Heart transplant surgery is currently the only option to completely restore cardiac function, but many patients die while waiting for a transplant due to a longstanding organ donor shortage. Thus, there is a dire need for accessible treatment options that can repair damaged hearts. Recent advances in tissue engineering and regenerative medicine have accelerated the development of therapies for …


Improving Sizing Resolution Of Particle Impactors In The Nanoparticle Range, Shivuday Kala Dec 2023

Improving Sizing Resolution Of Particle Impactors In The Nanoparticle Range, Shivuday Kala

All Dissertations

The application of particle size measurement extends across many fields: air quality measurement, pharmaceutical studies, paint and coating production, and nanoparticle formulation to name a few. Therefore, accurate measurement of nanoparticles is critical to aerosol science. While devices currently exist that can size and count nanoparticles such as electrical mobility spectrometers, dynamic light scattering devices, and small angle X-ray scattering devices, their high costs, complex operation, and lack of outdoor usability, restrict their use in practical applications. Among the devices that can size aerosols down to the nanoscale, cascade impactors stand out because of their robustness, relatively simple design, low …


Mindfulness As An Emotional Well-Being Tool For Beginning Teachers, Brittany Crumley Dec 2023

Mindfulness As An Emotional Well-Being Tool For Beginning Teachers, Brittany Crumley

All Dissertations

Today’s early educators are responsible for providing a stimulating learning environment to facilitate student academic outcomes, in addition to providing a positive emotional climate to support student social-emotional functioning. Early childhood educators engage with various physical and emotional stressors throughout the workday (e.g., disruptive behaviors, standardized assessment), and to be effective, they must be able to cope with their own emotional reactivity. Teacher experiences of work stress may lead to decreased performance, burnout, and poor student outcomes, creating serious concerns for the education environment. One transferable strategy to help teachers’ emotional well-being is mindfulness self-care (e.g., breathing practices), which can …


Embracing Identities And Affirming Agency: Exploring Effective Mentorship For Women Doctoral Students In Engineering Disciplines Using An Intersectional Lens, Jennifer Brown Dec 2023

Embracing Identities And Affirming Agency: Exploring Effective Mentorship For Women Doctoral Students In Engineering Disciplines Using An Intersectional Lens, Jennifer Brown

All Dissertations

Positive mentoring experiences are crucial for retaining and advancing those who hold marginalized identities in STEM, as they foster a greater sense of belonging and self-efficacy that encourage these students to persist in their fields. Marginalized identities in STEM include, but are not limited to, women, BIPOC (Black, Indigenous, and People of Color), low-income, first-generation, neurodivergent, and members of the LGBTQ+ community. Oftentimes, these identities intersect, introduce additional nuance in interactions within engineering spaces, and affect the mentoring support that both mentees and their mentors require.

Prior research has shown the reciprocal value that is created when graduate students are …


Experimental And Computational Platforms For Studying Systems Mechanobiology, Brendyn Miller Dec 2023

Experimental And Computational Platforms For Studying Systems Mechanobiology, Brendyn Miller

All Dissertations

Mechanical stimulation through physical activity has been shown to play an important role in treating and preventing several non-communicable diseases such as hypertension, lower back pain (LBP), type-2 diabetes mellitus, and several cancers. This is accomplished through the regulation of cellular behavior and tissue remodeling within the body at both the micro- and macro-scale levels. The goal of mechanobiology research is to gain in-depth knowledge and understanding of how cells sense physical forces in conjunction with other biochemical cues and translate those factors into important biological functions that either maintain tissue homeostasis or lead to pathological states. Understanding these processes …


Cellular Mechanism Of Pentagalloyl Glucose-Mediated Prevention And Reversal Of Abdominal Aortic Aneurysms, Greg Halsey Dec 2023

Cellular Mechanism Of Pentagalloyl Glucose-Mediated Prevention And Reversal Of Abdominal Aortic Aneurysms, Greg Halsey

All Dissertations

Abdominal aortic aneurysm (AAA) has been the 15th leading cause of death in persons older than 55 for the past ten years in several Western countries, with rupture resulting in an almost 100% mortality rate. AAA is a focal dilation of the aorta characterized by progressive loss of elastin and vascular smooth muscle cells (SMCs), as well as persistent inflammatory response [1]. The only treatment for AAA is surgery; however, the mortality post-procedure is still 1-4%, with a 15-30% chance of morbidity [2].

Pentagalloyl glucose (PGG) treatment is effective in the reversal of AAA. While its stabilizing interactions with extracellular …


Addressing Mercury Contamination From Artisanal Gold Mining In Colombia: Pollution Exposure, Health Risk, And Educational Efforts In The Communities Of La Toma, Colombia, Kelli Mccourt Dec 2023

Addressing Mercury Contamination From Artisanal Gold Mining In Colombia: Pollution Exposure, Health Risk, And Educational Efforts In The Communities Of La Toma, Colombia, Kelli Mccourt

All Dissertations

Artisanal and small-scale gold mining (ASGM) has become a primary environmental and public health concern in the region of Colombia known as Alto Cauca. The predominantly Afro-descendent communities of Yolombó and La Toma in Alto Cauca have experienced pollution linked to the use of mercury in the ASGM process. For the past decade, mercury has emerged as a contaminant of increasing concern in the communities due to its toxicity and ability to bioaccumulate and biomagnify. Likewise, mining in the region raises concerns over the leaching of metals into local waters. Given the complexity of risk and pollution in the communities, …


Hydrothermal Synthesis Of First-Row Transition Metal Polyanions Towards The Design Of Frustrated Magnetic Materials, Megan Smart Dec 2023

Hydrothermal Synthesis Of First-Row Transition Metal Polyanions Towards The Design Of Frustrated Magnetic Materials, Megan Smart

All Dissertations

Novel modern materials are constantly being discovered as humanity seeks constantly better improvement to the optics and electronics around us, from lasers used in medical therapies to the magnets and supercomputing chips in our phones. Inorganic oxides commonly draw inspiration from naturally occurring minerals to template new discoveries through substitution of similarly behaving elements with the goal of inducing certain desired properties, such as ferroelectricity or creating the elusive quantum spin liquid. While many minerals are silicates, its periodic table neighbor germanium(IV) has a rich and under-explored crystal chemistry that could contain many new structures and magnetic materials. Another common …


Characterization Of The Effects Of The Pyrazolopyrimidine Inhibitor Grassofermata (Nav-2729) In The Eukaryotic Pathogen Trypanosoma Brucei, Kristina Marie Parman Dec 2023

Characterization Of The Effects Of The Pyrazolopyrimidine Inhibitor Grassofermata (Nav-2729) In The Eukaryotic Pathogen Trypanosoma Brucei, Kristina Marie Parman

All Dissertations

The protozoan pathogen, Trypanosoma brucei, is the causative agent of sleeping sickness in humans and nagana in livestock in sub-Saharan Africa. T. brucei cycles between tsetse fly and mammalian hosts, and it is adapted to survive in diverse host tissues. Variant Surface Glycoprotein (VSG) plays a key role in immune evasion in the mammalian host. The VSG membrane anchor requires two myristates, 14-carbon saturated fatty acids (FAs) that are scarce in the host. T. brucei can synthesize FAs de novo, but also readily takes up exogenous FAs, despite lacking homologs to fatty acid uptake proteins found in other …


Influence Of Photoreactor Design Parameters On The Performance Of Ultraviolet Light-Induced Degradation Of Per-And Polyfluoroalkyl Substances By Bismuth Oxy Hydroxy Phosphate And Hexagonal Boron Nitride Photocatalystsinfluence Of Photoreactor Design Parameters On The Performance Of Ultraviolet Light-Induced Degradation Of Per-And Polyfluoroalkyl Substances By Bismuth Oxy Hydroxy Phosphate And Hexagonal Boron Nitride Photocatalysts, Mojtaba Qanbarzadeh Dec 2023

Influence Of Photoreactor Design Parameters On The Performance Of Ultraviolet Light-Induced Degradation Of Per-And Polyfluoroalkyl Substances By Bismuth Oxy Hydroxy Phosphate And Hexagonal Boron Nitride Photocatalystsinfluence Of Photoreactor Design Parameters On The Performance Of Ultraviolet Light-Induced Degradation Of Per-And Polyfluoroalkyl Substances By Bismuth Oxy Hydroxy Phosphate And Hexagonal Boron Nitride Photocatalysts, Mojtaba Qanbarzadeh

All Dissertations

The main objective of this study is to evaluate the practical applicability of heterogeneous photocatalysis technology powered by ultraviolet (UV) photons for the degradation of per and -polyfluoroalkyl substances (PFAS) in contaminated groundwater samples. For this purpose, bismuth oxyhydroxy phosphate (BOHP) and hexagonal boron nitride (hBN) were utilized as the main photocatalysts in slurry photodegradation systems. BOHP (Bi3O(OH)(PO4)2) is a wide bandgap semiconductor with high activity for degrading long-chain perfluorocarboxylic acids (PFCAs) in mild operational conditions. Boron nitride (BN) is another wide bandgap semiconductor material that was used in this study due to its …


The Effect Of Prior Virtual Reality Experience On Locomotion And Navigation In Virtual Environments, Moloud Nasiri Dec 2023

The Effect Of Prior Virtual Reality Experience On Locomotion And Navigation In Virtual Environments, Moloud Nasiri

All Dissertations

VirtualReality(VR) is becoming more accessible and widely utilized in crucial disciplines like training, communication, healthcare, and education. One of the important parts of VR applications is walking through virtual environments. So, researchers have broadly studied various kinds of walking in VR as it can reduce sickness, improve the sense of presence, and enhance the general user experience. Due to the recent availability of consumer Head Mounted Displays (HMDs), people are using HMDs in all sorts of different locations. It underscores the need for locomotion methods that allow users to move through large Immersive Virtual Environments (IVEs) when occupying a small …


Economic Analysis Of Sod-Seeded Summer Annuals For Forage And Grazing, Ivanelle Meyer Dec 2023

Economic Analysis Of Sod-Seeded Summer Annuals For Forage And Grazing, Ivanelle Meyer

Graduate Theses and Dissertations

Forage and pasture trials were conducted over the summers of 2021 and 2022 to assess how forage production and nutritive value of sorghum sudangrass, cowpea, and sorghum sudangrass-cowpea mixtures, sod-seeded to bermudagrass pasture would impact stocker cattle performance. The forage trials compared forage production and quality when poultry litter was surface or sub-surface applied biennially in comparison to a no poultry litter control. Poultry litter is a nutrient dense fertilizer utilized on pastures in the mid-southern United States to increase forage nutritive value and yield. Broadcasting poultry litter results in more nutrient losses due to runoff and nitrogen volatilization compared …


The Developmental Process For Adenoviral Vectored Canine Influenza Vaccines, Nicholas Jeanjaquet Dec 2023

The Developmental Process For Adenoviral Vectored Canine Influenza Vaccines, Nicholas Jeanjaquet

School of Biological Sciences: Dissertations, Theses, and Student Research

Canine Influenza Virus (CIV) is a recently emerged branch of Influenza A virus that is highly infectious in dogs. The first strain was isolated in 2003, and it has quickly become endemic in areas with dense dog populations, most notably in Asia. The proximity of dogs to humans, along with their potential to serve as mixing vessels for reassortment, raises concern for possible zoonotic transmission and a potential human pandemic. Available vaccines are not frequently updated and struggle to prevent the spread of currently circulating strains. This highlights the need for a new and more effective vaccine. We outline the …


Exchange Rate Responses And Volatility Spillover Effects During The Covid-19 Pandemic In Indonesia, Panky Tri Febiyansah Dec 2023

Exchange Rate Responses And Volatility Spillover Effects During The Covid-19 Pandemic In Indonesia, Panky Tri Febiyansah

Economics and Finance in Indonesia

This paper aims to assess the impact of the confirmed COVID-19 cases, the timing of the outbreak, and physical measures on the returns and spillover effects of exchange rate in Indonesia. The model will be tested by the exponential generalized autoregressive conditional heteroskedastic (EGARCH) process and the spillover volatility index. The study discovers that the confirmed cases, outbreak news, and the implementation of large-scale social restrictions simultaneously contribute to a leverage effect on the volatility of a direct quote of Indonesian Rupiah to Australian Dollar, Euro, US Dollar, Singapore Dollar, and Great British Pound. To a certain extent, the heatwave …


The Effect Of Financial Inclusion On Food Security: Evidence From Developing And Developed Countries, Yasmin Yasmin, Sekar Utami Setiastuti Dec 2023

The Effect Of Financial Inclusion On Food Security: Evidence From Developing And Developed Countries, Yasmin Yasmin, Sekar Utami Setiastuti

Economics and Finance in Indonesia

This study investigates the global impact of financial inclusion on food security, with a focus on both developing and developed countries. The study constructs a financial inclusion index using the Sarma method and secondary data sourced from IMF and World Bank databases. System GMM is employed as the estimation method due to its effectiveness in addressing endogeneity issues and its efficient and consistent use of instruments. The analysis reveals that financial inclusion has a positive and statistically significant effect on food security across all research sub-samples. In addition, the study incorporates interaction variables between financial inclusion and the COVID-19 pandemic …


Women, Power, And Cancer: A Lancet Commission, Ophira Ginsburg, Verna Vanderpuye, Ann Marie Beddoe, Nirmala Bhoo-Pathy, Freddie Bray, Carlo Caduf, Narjust Florez, Ibtihal Fadhil, Nazik Hammad, Miriam Mutebi Dec 2023

Women, Power, And Cancer: A Lancet Commission, Ophira Ginsburg, Verna Vanderpuye, Ann Marie Beddoe, Nirmala Bhoo-Pathy, Freddie Bray, Carlo Caduf, Narjust Florez, Ibtihal Fadhil, Nazik Hammad, Miriam Mutebi

General Surgery, East Africa

Women interact with cancer in complex ways, as healthy individuals participating in cancer prevention and screening activities, as individuals living with and beyond a cancer diagnosis, as caregivers for family members and friends, as patient advocates, as health workers and healthcare professionals, and as cancer researchers and policy makers. The topic of women and cancer spans broad terrain, beyond women’s cancers and the biomedical aspects of any type of cancer that women in all their diversities might experience. It is inclusive of the ways in which sex and gender influence exposures to cancer risk factors, interactions with the cancer health …


Advanced Breast Cancer Care: The Current Situation And Global Disparities, Aruni Ghose, Susannah Stanway, Bhawna Sirohi, Miriam Mutebi, Sarah Adomah Dec 2023

Advanced Breast Cancer Care: The Current Situation And Global Disparities, Aruni Ghose, Susannah Stanway, Bhawna Sirohi, Miriam Mutebi, Sarah Adomah

General Surgery, East Africa

Objectives: Advanced breast cancer (ABC) is an incurable disease. The number of people living with ABC has increased globally. Disparities in ABC care exist at both individual and system levels. ABC cases in most low- and middle-income countries (LMICs) are underreported due to a lack of national cancer registries. Harmonized guidelines for resource stratification and capacity building in LMICs are under way.

Data sources: MEDLINE, Cochrane, and Google Scholar databases were used.

Conclusion: To improve ABC outcomes and resolve disparities, more robust health systems or pathways need to be developed across the cancer continuum in addition to social education.

Implications …