Digital Commons Network^™

Plastic, It's What's For Dinner: A Preliminary Comparison Of Ingested Particles In Bottlenose Dolphins And Their Prey, Leslie B Hart, Miranda Dziobak, Randall S Wells, Elizabeth Berens Mccabe, Eric Conger, Tita Curtin, Maggie Knight, John Weinstein

Faculty, Staff and Student Publications

Microplastic ingestion was reported for common bottlenose dolphins (Tursiops truncatus) inhabiting Sarasota Bay, FL, USA, a community that also has prevalent exposure to plasticizers (i.e., phthalates) at concentrations higher than human reference populations. Exposure sources are currently unknown, but plastic-contaminated prey could be a vector. To explore the potential for trophic exposure, prey fish muscle and gastrointestinal tract (GIT) tissues and contents were screened for suspected microplastics, and particle properties (e.g., color, shape, surface texture) were compared with those observed in gastric samples from free-ranging dolphins. Twenty-nine fish across four species (hardhead catfish, Ariopsis felis; pigfish, Orthopristis …

Selection Of Surgical Modality For Massive Splenomegaly In Children, Yong Li, Congjun Wang, Weilong Chen, Chao Chen, Xianming Tang, Hong Wang, Jiabo Chen, Qiang Liu, Wei Li, Yanqiang Li, Peng Chen, Yige Luo, Cheng Su

Faculty, Staff and Student Publications

BACKGROUND: Laparoscopic splenectomy (LS), a treatment for both benign and malignant splenic diseases, can prove technically challenging in patients with massive splenomegaly. In particular, the optimal surgical modality for treating massive splenomegaly in children remains controversial.

METHODS: The clinicopathologic data of 289 pediatric patients undergoing splenectomy for massive splenomegaly were studied in a retrospective analysis. Accordingly, the patients were classified into the LS surgery group and open splenectomy (OS) surgery group. In the laparoscopy cohort, they were separated into two subgroups according to the method of surgery: the multi-incision laparoscopic splenectomy (MILS) and the single-incision laparoscopic splenectomy (SILS) surgery groups, …

Effects Of Antiresorptive Medications On Tooth Root Formation And Tooth Eruption In Paediatric Patients, Yuki Arai, Jeryl D English, Noriaki Ono, Wanida Ono

Faculty, Staff and Student Publications

Tooth eruption is a pivotal milestone for children's growth and development. This process involves with the formation of the tooth root, the periodontal ligament (PDL) and the alveolar bone, as the tooth crown penetrates the bone and gingiva to enter the oral cavity. This review aims to outline current knowledge of the adverse dental effects of antiresorptive medications. Recently, paediatric indications for antiresorptive medications, such as bisphosphonates (BPs), have emerged, and these agents are increasingly used in children and adolescents to cure pathological bone resorption associated with bone diseases and cancers. Since tooth eruption is accompanied by osteoclastic bone resorption, …

Multi-Omics Analysis In Developmental Bone Biology, Yuki Matsushita, Azumi Noguchi, Wanida Ono, Noriaki Ono

Faculty, Staff and Student Publications

Single-cell omics and multi-omics have revolutionized our understanding of molecular and cellular biological processes at a single-cell level. In bone biology, the combination of single-cell RNA-sequencing analyses and in vivo lineage-tracing approaches has successfully identified multi-cellular diversity and dynamics of skeletal cells. This established a new concept that bone growth and regeneration are regulated by concerted actions of multiple types of skeletal stem cells, which reside in spatiotemporally distinct niches. One important subtype is endosteal stem cells that are particularly abundant in young bone marrow. The discovery of this new skeletal stem cell type has been facilitated by single-cell multi-omics, …

Role Of The Immune System In Liver Transplantation And Its Implications For Therapeutic Interventions, Guanrong Chen, Xin Hu, Yingchen Huang, Xiaonan Xiang, Sheng Pan, Ronggao Chen, Xiao Xu

Faculty, Staff and Student Publications

Liver transplantation (LT) stands as the gold standard for treating end-stage liver disease and hepatocellular carcinoma, yet postoperative complications continue to impact survival rates. The liver's unique immune system, governed by a microenvironment of diverse immune cells, is disrupted during processes like ischemia-reperfusion injury posttransplantation, leading to immune imbalance, inflammation, and subsequent complications. In the posttransplantation period, immune cells within the liver collaboratively foster a tolerant environment, crucial for immune tolerance and liver regeneration. While clinical trials exploring cell therapy for LT complications exist, a comprehensive summary is lacking. This review provides an insight into the intricacies of the liver's …

The New Nci Precision Medicine Trials, Lyndsay N Harris, Charles D Blanke, Harry P Erba, James M Ford, Robert J Gray, Michael L Leblanc, Siwen Hu-Lieskovan, Mark R Litzow, Selina M Luger, Funda Meric-Bernstam, Peter J O'Dwyer, Megan K D Othus, Katerina Politi, Lois E Shepherd, Carmen J Allegra, Helen X Chen, S Percy Ivy, Larissa A Korde, Richard F Little, Lisa M Mcshane, Jeffrey A Moscow, David R Patton, Magdalena Thurin, Laura M Yee, James H Doroshow

Faculty, Staff and Student Publications

Basket, umbrella, and platform trial designs (master protocols) have emerged over the last decade to study precision medicine approaches in oncology. First-generation trials like NCI-MATCH (Molecular Analysis for Therapy Choice) have proven the principle that studying targeted therapies on a large scale is feasible both from the laboratory and clinical perspectives. However, single-agent targeted therapies have shown limited ability to control metastatic disease, despite careful matching of drug to target. As such, newer approaches employing combinations of targeted therapy, or targeted therapy with standard therapies, need to be considered. The NCI has recently embarked on three second-generation precision medicine trials …

Civil Practice And Procedure, Christopher S. Dadak

University of Richmond Law Review

This Article discusses Supreme Court of Virginia and, for the first time, Court of Appeals of Virginia analysis of procedural issues. The Article further discusses revisions to civil procedure provisions of the Code of Virginia and Rules of the Supreme Court of Virginia in the last year.

The Article first addresses opinions of the supreme court and court of appeals, then new legislation enacted during the 2023 General Assembly Session, and finally revisions to the Rules of the Supreme Court of Virginia.

Ethofumesate-Resistant Annual Bluegrass (Poa Annua) In Grass Seed Production Systems, Vera Vukovic, Clint M. Mattox, Alec R. Kowalewski, Brandon C. Mcnally, Cale A. Bigelow, Stephen L. Meyers, James T. Brosnan, Aaron J. Patton

Department of Horticulture & Landscape Architecture Faculty Publications

The prolific seed production and polyploidy of annual bluegrass allow for the rapid development of herbicide resistance. Ethofumesate-resistant annual bluegrass plants were identified in the 1990s in grass seed production in Oregon, but their prevalence and distribution are not well documented. Therefore a dose–response experiment was initiated to determine the potential level of ethofumesate resistance in seed production systems. Seeds from 55 annual bluegrass populations were obtained from three sources: seed production fields (31 populations), the seed cleaning process (6 populations), and seed testing lots prior to retail distribution (18 populations). Additionally, two populations, one with known ethofumesate resistance and …

Covid-19 Responses Restricted Abilities And Aspirations For Mobility And Migration: Insights From Diverse Cities In Four Continents, Dominique Jolivet, Sonja Fransen, William Neil Adger, Anita Fábos, Mumuni Abu, Charlotte Allen, Emily Boyd, Edward R. Carr, Samuel Nii Ardey Codjoe, Maria Franco Gavonel, François Gemenne, Mahmudol Hasan Rocky, Jozefina Lantz, Domingos Maculule, Ricardo Safra De Campos, Tasneem Siddiqui, Caroline Zickgraf

Sustainability and Social Justice

Research on the impacts of COVID-19 on mobility has focused primarily on the increased health vulnerabilities of involuntary migrant and displaced populations. But virtually all migration flows have been truncated and altered because of reduced economic and mobility opportunities of migrants. Here we use a well-established framework of migration decision-making, whereby individual decisions combine the aspiration and ability to migrate, to explain how public responses to the COVID-19 pandemic alter migration patterns among urban populations across the world. The principal responses to COVID-19 pandemic that affected migration are: 1) through travel restrictions and border closures, 2) by affecting abilities to …

Exploratory Analysis Of Medication Adherence And Social Determinants Ofhealth Among Older Adults With Diabetes, M. L. Blakely, F. Sherbeny, T. J. Hastings, L. Boyd, Omolola A. Adeoye-Olatunde

Department of Pharmacy Practice Faculty Publications

Background

Diabetes is the fifth leading cause of death in the United States (US), affecting approximately 27%, or 15.9 million adults 65 years of age and older. Diabetes is the most expensive chronic condition in the US and accounts for the second largest avoidable healthcare cost. Adherence to long-term medication treatment plans is crucial among patients with diabetes because it decreases risk of developing comorbid conditions and improves quality of life. Greater exposure to adverse social determinants of health (SDOH) over an individual's lifespan can result in worse health outcomes. Hence, it is important to obtain a better understanding of …

Fly-Cure, A Multi-Institutional Cure Using Drosophila, Increases Students' Confidence, Sense Of Belonging, And Persistence In Research, Julia A. Markle, Olivier Devergne, Seth M. Kelly, Paula A. Croonquist, Cory J. Evans, Melanie A. Hwalek, Victoria L. Straub, Danielle R. Hamill, Alexandra Peister, David P. Puthoff

Biology Faculty Works

The Fly-CURE is a genetics-focused multi-institutional Course-Based Undergraduate Research Experience (CURE) that provides undergraduate students with hands-on research experiences within a course. Through the Fly-CURE, undergraduate students at diverse types of higher education institutions across the United States map and characterize novel mutants isolated from a genetic screen in Drosophila melanogaster. To date, more than 20 mutants have been studied across 20 institutions, and our scientific data have led to eleven publications with more than 500 students as authors. To evaluate the impact of the Fly-CURE experience on students, we developed and validated assessment tools to identify students’ perceived research …

Using Mindfulness Through Doodling In Interactive Notebooking To Increase Student Achievement, Michelle Brown

Dissertations

The SARS-CoV-2 pandemic, which unfolded from 2019 to 2021, disrupted education systems worldwide, leading to significant learning loss and inequities. The shift to digital learning, necessitated by the pandemic, presented challenges such as learning loss and social-emotional impacts. This study investigates the incorporation of Social Emotional Learning(SEL), with mindfulness, into the school curriculum to address these challenges.

The focus of the study is on the implementation of Mindful Doodling as a component of SEL within an interactive notebook in a middle school science curriculum to enhance student achievement. The study aimed to analyze how different amounts of Mindful Doodling in …

The Effect Of Step Rate Training On Running Economy And Biomechanics, Nahir Negron-Fernandez

All NMU Master's Theses

It is known that running economy is a determinant of running performance. Increased step rate has been correlated with improved running economy, but it is unknown whether these improvements can be maintained with chronic training. The purpose of this study was to determine if a step rate training intervention improves running economy and improves lower body kinetic factors in distance runners. Nine participants were randomly assigned to either an intervention group (n = 7) undergoing a 6-week supplemental training program, or a non-training control group (n = 2). The intervention group trained three times a week, running at a higher …

Cognitive Task Analysis Of Clinicians’ Drug–Drug Interaction Management During Patient Care And Implications For Alert Design, Alissa L. Russ-Jara, Nervana Elkhadragy, Karen J. Arthur, Julie B. Dilulio, Laura G. Militello, Amanda P. Ifeachor, Peter A. Glassman, Alan J. Zillich, Michael Weiner

Purdue University Libraries Open Access Publishing Fund

Background Drug–drug interactions (DDIs) are common and can result in patient harm. Electronic health records warn clinicians about DDIs via alerts, but the clinical decision support they provide is inadequate. Little is known about clinicians’ real-world DDI decision-making process to inform more effective alerts.

Objective Apply cognitive task analysis techniques to determine informational cues used by clinicians to manage DDIs and identify opportunities to improve alerts.

Design Clinicians submitted incident forms involving DDIs, which were eligible for inclusion if there was potential for serious patient harm. For selected incidents, we met with the clinician for a 60 min interview. Each …

Dietary And Supplemental Intake Of Vitamins C And E Is Associated With Altered Dna Methylation In An Epigenome-Wide Association Study Meta-Analysis, Amena Keshawarz, Roby Joehanes, Jiantao Ma, Gha Y. Lee, Ricardo Costeira, Pei-Chien Tsai, Olatz M. Masachs, Jordana T. Bell, Rory Wilson, Barbara Thorand, Juliane Winkelmann, Annette Peters, Jakob Linseisen, Melanie Waldenberger, Terho Lehtimäki, Pashupati P. Mishra, Mika Kähönen, Olli Raitakari, Mika Helminen, Carol A. Wang, Phillip E. Melton, Rae-Chi Huang, Craig E. Pennell, Therese A. O’Sullivan, Carolina Ochoa-Rosales, Trudy Voortman, Joyce B.J. Van Meurs, Kristin L. Young, Misa Graff, Yujie Wang, Douglas P. Kiel, Caren E. Smith, Paul F. Jacques, Daniel Levy

Research outputs 2022 to 2026

BACKGROUND: Dietary intake of antioxidants such as vitamins C and E protect against oxidative stress, and may also be associated with altered DNA methylation patterns. METHODS: We meta-analysed epigenome-wide association study (EWAS) results from 11,866 participants across eight population-based cohorts to evaluate the association between self-reported dietary and supplemental intake of vitamins C and E with DNA methylation. EWAS were adjusted for age, sex, BMI, caloric intake, blood cell type proportion, smoking status, alcohol consumption, and technical covariates. Significant results of the meta-analysis were subsequently evaluated in gene set enrichment analysis (GSEA) and expression quantitative trait methylation (eQTM) analysis. RESULTS: …

Using Readers' Theater To Increase Fluency For Second Grade Students, Serena Coyle

Dissertations, Theses, and Projects

This study focuses the effect of reader’s theater on fluency for second-grade students. Fluency was measured through oral reading fluency and the multidimensional fluency scale. Students were selected from the researcher’s second-grade classroom. The study was done in a small group setting. Results show that students significantly improved oral reading fluency and prosody in the six-week study. Students grew an average of 24 words per minute in oral reading fluency.

Editorial Board

Nursing & Health Sciences Research Journal

No abstract provided.

Letter From The Editor: Six Years Of Successful Publication, Nohemi Sadule Rios

Nursing & Health Sciences Research Journal

No abstract provided.

Empowering Nursing Staff To Activate Rapid Response Teams: Using In Situ Simulation To Bolster Knowledge And Confidence, Elicia Egozcue, Marrice A. King, Natalie Bermudez, Nohemi Sadule Rios, Mayra Villalba, Ashley Miller

Nursing & Health Sciences Research Journal

Purpose: To examine the impact of in situ simulation (ISS) with scripting on nursing staff’s knowledge and confidence to initiate rapid response teams (RRTs) immediately after identifying patient condition deterioration. Background/Significance: Failure to rescue (FTR) related to delays in activation of RRT is on the rise, leading to poor patient outcomes. Lack of confidence, knowledge, and empowerment are associated with delayed activation of RRTs. As such, the nursing staff’s confidence is integral in activating RRTs and FTR prevention. In situ simulation may help nurses increase their confidence, thus empowering timely RRT initiation. Methods: This quantitative pretest–posttest study used a convenience …

Comparison Of Microbial Respiratory Cultures Versus Mrsa Nasal Screen To Guide Vancomycin De-Escalation In Patients Hospitalized For Bacterial Pneumonia, Victoria E. Grusauskas, Anthony Wasielewski, Kristin Boyar

Nursing & Health Sciences Research Journal

Background: Methicillin-resistant Staphylococcus aureus (MRSA) nasal screen identifies the presence of MRSA nasal colonization, which can be used as a valuable antimicrobial stewardship tool to de-escalate empiric vancomycin therapy in patients with pneumonia. Current practices at a Florida hospital include using respiratory culture and MRSA nasal screening results to assist in treating MRSA pneumonia infections. This study aimed to evaluate the total duration of vancomycin therapy in patients with suspected MRSA respiratory tract infections. Methods: This was a single-center, retrospective chart review conducted at a tertiary medical center. Adult patients were assigned to either the respiratory culture-directed group or the …

Nurses - Tab Down Your Stress Level: A Pilot Study On The Use Of Aromatherapy To Decrease Stress Levels, Judith E. Bowling, Ashley N. Garbutt, Theresa Worden, Julie Erickson, Nicole Rowney

Nursing & Health Sciences Research Journal

Introduction: The average day-to-day nursing profession is a stressful one. The job often requires dealing with patients enduring some of the worst times of their lives, as well as contending with patients' emotional family members. This stressful environment is heightened even more for nurses employed in critical access hospitals (CAHs) due to the limited resources usually associated with these smaller facilities. Methods: Research and Evidence-Based Practice Council members at one CAH explored how to help nurses deal with the elevated work stress level. Aromatherapy tabs were used as an intervention to reduce nurses' stress. The nurses who participated in this …

Prevalence Of Substance Use Among Lesbian, Gay, And Bisexual High School Students In 2019 Vs. 2021, Jordyn Lee, Elisabeth Hayes, Adam Wyatt

Nursing & Health Sciences Research Journal

Background: Studies suggest that LGBTQ+ (lesbian, gay, bisexual, transgender, queer/questioning, plus) youth are at increased risk of engaging in alcohol and substance use. The COVID-19 pandemic forced many students to isolate in 2020 and 2021, and the impacts of this have been purported to be detrimental. This study examines the prevalence of alcohol and substance use among lesbian, gay, and bisexual (LGB) U.S. high school students before the pandemic in 2019 versus 2021. Methods: This cross-sectional descriptive study used results from the 2019 Youth Risk Behavior Survey (YRBS) and the 2021 Adolescent Behavior and Experiences Survey (ABES). The 2019 YRBS …

The Use Of Descriptive Analytics To Improve Nursing Compliance With Bar Code Medication Administration In The Outpatient Setting, Janisse Post, Stefania Granados, Elyse Garcia, Gloria Arteaga, Cristina Lopez

Nursing & Health Sciences Research Journal

Background: Bar Code Medication Administration (BCMA) has been shown to reduce medication errors and improve patient outcomes. The utilization of this technology-driven approach enhances patient care and has emerged as a potent strategy to decrease medication errors. Purpose: This project aimed to examine the impact of descriptive analytics in improving BCMA compliance to reduce medication errors in acute outpatient settings. Methods: In March 2021, baseline data revealed that overall BCMA compliance was 87%, with only 1 out of 20 outpatient units meeting the 95% benchmark. To enhance overall efficiency and effectiveness, our team took a multi-faceted approach, including streamlining the …

Evaluating A Novel Patient Intake Model For Newly Referred Patients Seeking Cancer Care: An Evidence-Based Practice Project, Roquinna Serna, Stella Fernandez, Morgan Nestingen, Stephen Breazeale

Nursing & Health Sciences Research Journal

Introduction: Cancer survivors must engage in a complex medical system that requires coordinating care, traveling for treatment, obtaining referrals, and scheduling multiple appointments with various teams. Cancer care facilities are implementing oncology navigation programs that help survivors navigate barriers in complex cancer care systems. However, new patients require additional support prior to their first visit. This article aims to describe the development and design of Miami Cancer Institute’s (MCI) Intake NOW program and evaluate its effects on scheduling-related outcomes among individuals seeking to establish cancer care. Methods: We conducted a retrospective data analysis before and after the MCI Intake NOW …

The Information Literacy Class As Theatrical Performance: A Qualitative Study Of Academic Librarians’ Understanding Of Their Teacher Identity, Mark Aaron Polger

Publications and Research

This qualitative study examines how academic librarians understand, conceptualize, and describe their teacher identity. The role of the academic librarian has greatly changed due to the advent of information technology. Traditionally, they were generalists, who were responsible for selecting and maintaining library collections. Academic librarian roles have evolved into web developers, information literacy (IL) instructors, emerging technology innovators, marketing and outreach coordinators, open education resources (OER) advocates, and scholarly communication experts. This research investigates the academic librarian as teacher phenomenon, how they describe their professional identity as teachers, the skills, knowledge, and competencies they teach, and their beliefs of how …

"If You're On Time, You're Late": Law School Application Timing Among Historically Underrepresented Applicants, Sherrie K. Godette, K. L. Risman, Tiffane Cochran, Baylee Jenkins

AccessLex Institute Research

The “not so big” secret of college and graduate school admissions is that applicants who apply early are more likely to receive an offer of admission than those who apply closer to the final deadline. The same is true for law school applicants. When applicants submit applications later, their admission chances may be lower simply due to the timing of their application rather than their qualifications. Applicants who identify as underrepresented people of color (uPOC) or socioeconomically disadvantaged are less likely to apply early to law school or utilize formal early decision programs. In other words, applicants who identify as …

“And I’M Going To Destroy You.”: Persona And Gender Performativity In Ernest Hemingway’S The Garden Of Eden, Nicole Minton

UNLV Theses, Dissertations, Professional Papers, and Capstones

While debate of Ernest Hemingway’s authorial masculine persona in connection to The Garden of Eden has been a point of interest in literary scholarship, no single work has tied together theory of gender performativity to persona. A borderline parodic display of masculine adventure has encouraged a one-dimensional view of Hemingway, who is viewed by audiences as the pinnacle of masculinity. However, this image is complicated by the publication of Eden, which reveals an author interested in gender and sexual identity fluidity. Rarely has a single text called into question so controversially an author’s public image. Eden showcases an empathetic …

Application Of Biochar For Antibiotic-Free Nutrient Recovery From Source-Separated Human Urine, Sayeda Ummeh Masrura

UNLV Theses, Dissertations, Professional Papers, and Capstones

In recent years, the application of biochar as a soil amendment has gained attention as a potential solution for nutrient management and environmental remediation. Biochar, a carbon-rich material produced through the pyrolysis of biomass under oxygen-limited conditions, exhibits unique physicochemical properties making it an effective sorbent for nutrients and contaminants. Its high surface area, porosity, and stability provide an ideal matrix for nutrient retention and release, as well as the immobilization of pollutants. One area of particular interest is the application of biochar for nutrient recovery from source-separated human urine. Source separation of urine has gained momentum as a sustainable …

Optimized Indoor Temperature In Office Buildings Through Personalized Thermal Comfort Modeling, Raviteja Patchava

UNLV Theses, Dissertations, Professional Papers, and Capstones

Building occupants experience varying thermal comforts at static indoor set-point temperatures due to variances in preferences, needs, and activities, both within and among individuals. Despite advancement in smart building control systems, many building occupants remain dissatisfied with indoor temperatures. This study developed and created an optimization model to predict the optimized indoor temperature preferences in multiple-occupancy settings. To achieve this, personalized thermal comfort models for each occupant in a multiple occupancy space were developed. The personal comfort models serve as the foundation for predicting their individual thermal preference and developing indoor temperature optimization model. When predicting the individual thermal preference, …

Physiological And Biomechanical Response To Indoor Cycling With And Without The Ability To Sway, Alina P. Swafford

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Bicycles have been around since the early 19th century. Since the invention of the bicycle, it has taken on several purposes. People have used bicycles as a means of transportation, leisure, exercise, and sport. The number of individuals who participate in a cycling event per year has increased. With the increase in popularity, research related to cycling has also increased. Research related to the physiology and biomechanics of cycling are of particular areas of interest. Balance is a crucial component of understanding why we cycle a certain way. Some research has labeled balancing on a bicycle as cycling sway. …