Digital Commons Network^™

Language Contest In The Linguistic Landscape Of Sabasaba International Trade Exhibitions In Dar Es Salaam, Tanzania, Emmanuel Ilonga

Journal of Humanities and Social Sciences

This inquiry stems from the scarcity of research on linguistic landscape particularly on the intersection between physical landscape, business fairs, and languages in Dar es Salaam. Essentially, it discusses the complexities of linguistic signs at the Dar es Salaam International Trade Fair (DITF) in Tanzania. The central purposes are grounded in the roles of information and symbolism, power dynamics, group identities, language policies, and rationale for the use of specific languages at the fair. Photographic method was employed in the generation of data. The analysis of data was framed in line with informational and symbolic frameworks, and structuration principles. The …

The Role Of Cooperatives And Farmer-Industry Linkages In The Evolution Of Tanga’S Dairy Innovation System, Hezron Makundi, Heric Thomas

Journal of Humanities and Social Sciences

This study investigated the development of Tanga’s dairy innovation system and its role in promoting and maintaining relationships between farmers, the industry, and cooperative unions; employing a case study approach. The main objective was to assess the role of cooperatives in forging farmer-industry linkages and in improving dairy industry innovations. 100 dairy producers in Tanga participated in the survey that led to the paper. A questionnaire was used to collect data from randomly selected farmers. Furthermore, 20 key informant interviews were conducted with various participants, including the Tanga Dairy Cooperative Union livestock extension service providers. Also, one Focus Group Discussion …

Exploring The Value Of Cannabis And Changing Mindset For Advancing Socio-Economic Development In Tanzania, 1891–2023, Iddy Ramadhani Magoti

Journal of Humanities and Social Sciences

This paper examines the origin, cultivation, laws, values, uses and other cultural practices connected to cannabis in Tanzania, and other parts of the world, for the purpose of contributing to the existing debate on whether cannabis should be legalised or illegalised in Tanzania and other parts of Africa. The data for this study were collected from both primary and secondary sources, including published documents, oral sources, archival documents and newspapers. Based on the evidence collected, I argue that the values and other benefits accrued from the cultivation and uses of cannabis outweigh the negative impacts which policy makers capitalize on …

A Real-World Study Of Pneumonitis In Non-Small Cell Lung Cancer Patients Receiving Durvalumab Following Concurrent Chemoradiation, Neha Akkad, Theodore S. Thomas, Suhong Luo, Eric Knoche, Kristen M. Sanfilippo, Jesse W. Keller

2020-Current year OA Pubs

BACKGROUND: Locally advanced non-small cell lung cancer (LA-NSCLC) treated with the programmed death-ligand 1 inhibitor durvalumab has been associated with significant rates of pneumonitis, which has led to higher rates of discontinuation of therapy in real-world populations. Thus far there has been no consensus in the literature on the impact of pneumonitis on survival.

METHODS: This is a retrospective cohort study of veterans receiving durvalumab between 12/5/2017 and 4/15/2020. Participants were identified using VINCI data services. Patients were followed through 9/14/2021. Development of clinical pneumonitis was assessed through review of documentation and graded using CTCAE 4.0 criteria. Univariate logistic regression …

Colon Targeted Delivery Dosage Forms For Probiotics: A Review, Gede Anom Anjasmara, Pietradewi Hartrianti, Raditya Iswandana

Pharmaceutical Sciences and Research

Encapsulation was a promising method for protecting probiotics from extreme conditions during their passage through the gastrointestinal tract and delivering probiotics to specific sites in the colon for colonization. Various dosage forms have been used in recent years to encapsulate probiotics to maintain cell viability during processing, storage, and through the digestive tract to provide health benefits. However, research related to the encapsulation of probiotics as the dosage forms for colon-targeted delivery systems was still quite limited to conventional dosage forms due to the sensitivity of probiotics to extreme conditions during the process. This review focuses on various types of …

Molecular Docking Analysis Of Acanthus Ilicifolius Compounds Toward Cul4b-Ddb1-Ahr-Erα Complex Protein For Antiosteoporosis Discovery, Binar Asrining Dhiani, Sarmoko Sarmoko, Retno Wahyuningrum, Akbar Yulianto

Pharmaceutical Sciences and Research

Osteoporosis represents a significant global public health issue, particularly among the aging population. Its incidence reaches 18.3% of the total population, with the highest prevalence observed in elderly postmenopausal women. A key factor in osteoporosis is the decreased expression level of estrogen receptor alpha (ERα), attributed to its degradation by the ubiquitin ligase protein complex Cullin4B (CUL4B), DNA damage binding 1 (DDB1), and aryl hydrocarbon receptor (AhR), collectively known as CUL4BAhR. Acanthus ilicifolius L contains compounds exhibiting antiosteoporosis activity, primarily by inhibiting osteoclastogenesis via RANKL. However, no reports exist of antiosteoporosis agents that act by inhibiting ERα degradation via CUL4BAhR. …

Exploring Rosella (Hibiscus Sabdariffa L.) Calyx Extracts As Natural Dye And Antioxidants In Lip Cream Product: Formulation And Evaluation, Donna Maretta Ariestanti, Abdul Mun'im, Joshita Djajadisastra, Riska Amalia Putri Hutami, Redhalfi Fadhila, Richard Johari James

Pharmaceutical Sciences and Research

Rosella, also known as Hibiscus sabdariffa L., is a plant that contains anthocyanin compounds in its calyx, which are known for their antioxidant properties. These compounds give the plant a captivating red color and can be used as natural dyes. This study aimed to exploit anthocyanins in rosella calyx as natural dyes and antioxidants in lip cream product. The formulations employed extracts from rosella calyx, a viscous extract from maceration in 96% ethanol (F1) and a commercially available powdered rosella extract (F2). Evaluation on the formulations demonstrated that both F1 and F2 effectively maintained the color integrity of the lip …

Subchronic Toxicity Study Of Sterculia Rubiginosa Zoll. Ex Miq. Leaves Extract, Rini Prastiwi, Ester Hidayati, Riska Anggraini, Cut Mauliza, Ita Anggraini, Ema Dewanti

Pharmaceutical Sciences and Research

Ki hampelas (Sterculia rubiginosa Zoll. Ex Miq.) is traditionally used as an antiasthma. It also reported has antioxidant and nephroprotective activity. This study was conducted to evaluate the subchronic toxicity of the leaf extract of ki hampelas. The extract was orally administered to male and female Sprague-Dawley rats at doses of 50, 200, and 400 mg/kg bodyweight (BW) per day for 28 days. The rats were divided into four groups, consist of consist of normal group (Na CMC 0.5%), dose 1 (50 mg/kg BW), dose 2 (200 mg/kg BW), and dose 3 (400 mg/ kg BW) of extract. The …

Antioxidant Activities Of Roja Herbal Tea: Combination Of Rosella Flower (Hibiscus Sabdariffa L.) And Ginger Rhizome (Zingiber Officinale Rosc.), Wahyu Widowati, Teresa Liliana Wargasetia, Teddy Marcus Zakaria, Michael Sebastian Gunadi, Nathanael Halim, Sherly Santiadi, Hanna Sari Widya Kusuma, Nida Firyal Fauziyah

Pharmaceutical Sciences and Research

Herbal teas and plant-based medicines have been widely used worldwide for their therapeutic and healing qualities. Rosella (Hibiscus sabdariffa L.) has various benefits in preventing digestive problems, liver disease, fever, and others. Ginger (Zingiber officinale Rosc.) or known as jahe in Indonesia is believed to benefit numerous clinical conditions linked to oxidative stress, including pancreatitis, hypertension, diabetic kidney disease, Alzheimer’s disease, and tumor development. They have been utilized in traditional medical practice to treat conditions such as fever, nausea, and headaches. In this study, we aimed to determine the antioxidant activities of rosella flower tea, ginger tea, and …

Study Of Anti-Hyperuricemia, Anti-Inflammatory, And Anti-Nociceptive Effects Of Hylocereus Undatus Stem Bark Extract In Animal Models, Tri Wahyuni, Sartika Harka Putri, Anton Bahtiar

Pharmaceutical Sciences and Research

Dragon fruit, known as Hylocereus undantus (HU), has traditionally been utilized in Banyuwangi, East Java, Indonesia, for addressing gout and rheumatism. Despite its empirical use, there is a lack of reported pharmacological research on this plant. This study aimed to explore the properties of HU extract in treating hyperuricemia, inflammation, and pain. Adenine-potassium oxonate-induced mice were employed to evaluate anti-hyperuricemia activity, measuring uric acid, blood urea nitrogen (BUN), and creatinine serum levels. Carrageenan-induced paw edema in rats was used to assess anti-inflammatory activity, while acetic acid-induced abdominal writhing and hot plate tests were conducted to investigate anti-nociceptive effects. The results …

Genetic Inactivation Of Β-Catenin Is Salubrious, Whereas Its Activation Is Deleterious In Desmoplakin Cardiomyopathy, Melis Olcum, Siyang Fan, Leila Rouhi, Sirisha Cheedipudi, Benjamin Cathcart, Hyun-Hwan Jeong, Zhongming Zhao, Priyatansh Gurha, Ali J Marian

Faculty, Staff and Student Publications

AIMS: Mutations in the DSP gene encoding desmoplakin, a constituent of the desmosomes at the intercalated discs (IDs), cause a phenotype that spans arrhythmogenic cardiomyopathy (ACM) and dilated cardiomyopathy. It is typically characterized by biventricular enlargement and dysfunction, myocardial fibrosis, cell death, and arrhythmias. The canonical wingless-related integration (cWNT)/β-catenin pathway is implicated in the pathogenesis of ACM. The β-catenin is an indispensable co-transcriptional regulator of the cWNT pathway and a member of the IDs. We genetically inactivated or activated β-catenin to determine its role in the pathogenesis of desmoplakin cardiomyopathy.

METHODS AND RESULTS: The Dsp gene was conditionally deleted in …

Lichen Amyloidosis Treated With Topical Combination Therapy And Narrowband Ultraviolet B Phototherapy, Ulfah Hasna Hasibah, Siti Aisha Nabila Ferina, Eka Komarasari, Prima Kartika Esti, Lenti Perangin Angin

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Lichen amyloidosis (LA) is characterized by linear rows of firm, pigmented, grouped, hyperkeratotic papules that can form a plaque, usually occurring on the shins and forearms, with intense itch as the prominent symptom.

Case Illustration: A 57-year-old female complained of brown spots on her shins and arms that gradually thickened six years ago. The lesions were brown, multiple, discrete, slightly scaly papules forming hyperpigmented plaques. The result of the histopathology examination showed an acanthotic epidermis with hyperkeratotic foci and eosinophilic amorphous mass deposits in the papillary dermis with brown pigments. The working diagnosis was lichen amyloidosis. Topical …

Exploring The Relationship Between Nonprofit Management Education Programs And Their Local Nonprofit Sector, Elise L. Kieffer

Journal of Nonprofit Innovation

This study sought to explore the relationship between nonprofit management education programs at institutions of higher education with nonprofit organizations in their local communities. Using a pragmatism methodology, I conducted interviews with directors of nonprofit management education programs and with corresponding nonprofit partners in their local communities. While research exists exploring the impacts and influences of nonprofit academic centers on their local sector - specifically regarding the training of practitioners - there is much less available in published literature exploring the actual effects of nonprofit management education programs on their local communities. This study begins what must be a more …

A New Secret Of The Youth Olympic Games: A Model For Olympic Facilities Reform, Jeffrey Petersen, Lawrence W. Judge

Journal of Applied Sport Management

The authors center their attention on Olympic venues and the Youth Olympic Games (YOG), arguing that a new reform model for Olympic venues should be based on the model of the YOG. Although the focus of the proposed reform model remains on venue reform, the authors also considers all four elements from Müller’s (2015) mega-events definitional model. These elements include visitor attractiveness (tickets sold), mediated reach (broadcast rights fees), cost (total cost), and transformation (capital investment). The reform model is argued to improve the overall cost and long-term impact of Olympic Games infrastructure, making it more manageable and sustainable.

Favorable Benefits Of Autologous Serum Therapy In Chronic Spontaneous Urticaria, Sanjana Agrahara Shantharaju, Amrita Hongal, Diksha Gupta, Girishma Jonnagadla

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: In chronic spontaneous urticaria (CSU), autologous serum therapy (AST) is an alternative treatment modality that provides promising benefit of extended relief period without side effects and economic burden of pills. This study aimed to assesses the efficacy of AST in CSU patients irrespective of their autologous serum skin test (ASST) result.

Methods: Patients were enrolled based on inclusion and exclusion criteria after taking written informed consent. A detailed history and clinical examination & relevant investigations were done. ASST was performed and irrespective of the test result AST was given to all study subjects that included weekly intramuscular …

Investigating Teachers’ Sensemaking Process And Experiences Of Working With Students With Labels Of Autism In Saudi Arabian Public Schools: A Qualitative Collective Case Study, Hind Alharbi

Theses and Dissertations

In this dissertation, I conducted a collective qualitative case study to understand the personal experiences and sensemaking processes that teachers developed to educate students with labels of autism in inclusion settings in Riyadh public schools. Specifically, I aimed to understand how teachers’ attitudes, beliefs, and knowledge regarding the inclusion of autistic students explained why teachers did what they did in their school context. In three rounds of semistructured interviews with eight teachers, participants explained their experiences and process of teaching students with autism. Participants also shared documents and artifacts to provide a deeper understanding of the nature of inclusion offered …

Comparative Study Of Mendol As An Indonesian Traditional Side Dish In Food Tourism, Laksono Budiarto, Titi Mutiara Kiranawati, Kaede Shirakane

Bulletin of Culinary Art and Hospitality

Efforts to stimulate economic growth, especially after the impact of the pandemic, are currently being undertaken worldwide. The tourism sector, a major economic driver, is transforming strategically. One promising strategy involves promoting traditional cuisine to enhance culinary tourism. Indonesian traditional dishes are an essential aspect of cultural heritage, and mendol is one of Indonesia’s original signature dishes, particularly in Malang, East Java. This research aims to understand the highly sought-after combination of mendol dishes along with traditional Indonesian cuisine through Twitter data analysis. The study employs the Apriori algorithm to analyze the Twitter data’s frequent item sets and association rules. …

Relation Between Gross Motor Function, Consumption Pattern And Macronutrient Intake With Nutritional Status Cerebral Palsy, Almas Barizah Fathaniah, Eka Andriani, Sabrina Sabrina

Bulletin of Culinary Art and Hospitality

Cerebral Palsy is a condition of motor disturbances caused by brain damage during child development. Globally, the incidence of CP in low- and middle income countries is 3.4 per 1000 live births. Cerebral Palsy (CP) is defined from the word cerebral, namely the brain, and palsy which is paralysis or a paralyzed condition caused by a nerve disorder that functions to regulate the movement of the body's muscles. The purpose of this study was to analyze the description and relationship between the level of gross motor skills, diet, and intake of macronutrients with nutritional status in people with cerebral palsy. …

Proximate Analysis Of Dewandaru Fruit (Eugenia Uniflora L.) Dried Sweets, Mazarina Devi, Soenar Soekopitojo, Laili Hidayati, Issutarti Issutarti, Wiwik Wahyuni, Mansoor Abdul Hamid, Naufal Kukuh Tata Asri

Bulletin of Culinary Art and Hospitality

Dried sweet fruit is a diversified food product that is popular in Indonesia. Dewandaru fruit (Eugenia uniflora L.) dried sweets are expected to be a preferred and beneficial product for health. This study aimed to analyze the Proximate content of Dewandaru fruit. This experimental study utilized a Completely Randomized Design (CRD) with four different drying time treatments consisting of 4 levels (6 hours, 7 hours, 8 hours, and 9 hours) and 2 replications. Observation data were analyzed using One-way ANOVA followed by the DMRT test. The results showed that Dewandaru dried sweets with a drying time of nine hours had …

Perception Of Quality Of Life Among Fifth Grade Preparatory School Students In Baghdad, Reem Faisal Rajab, Sahira Razzaq Kadhim, Ali Salam Al-Yaaribi

Modern Sport

The research aims to study the quality of life among preparatory school students in Baghdad, particularly in the context of current social circumstances, encompassing both male and female students. The study utilizes a quality-of-life scale developed by Noor Latif Abdul Zahra, comprising 54 items distributed across ten dimensions. These dimensions include physical health, mental skills, psychological well-being, resilience, optimism and satisfaction, self-independence and self-efficacy, job satisfaction, social support, social status, and moral values. The research problem revolved around the question: "Is there a sense of quality of life among fifth-grade preparatory school students (both males and females)?" The researchers established …

The Effect Of Bungee And Similar Physical Exercises Using Rubber Ropes On Learning Some Skills Of Backstroke For Female Students, Third Stage, College Of Physical Education And Sports Sciences For Women - University Of Baghdad, Sabah Latif Hasan, Mawahib Hameed Numan

Modern Sport

In download of the tremendous development we are experiencing today and the information revolution, researchers and specialists, despite their different downloads on the best methods of education in general and motor learning in particular, are seeking to innovate modern educational methods to acquire motor skills that are based on the foundations and principles of motor education, which requires variable learning processes. Its priority is the methods and types of applied exercises used in the learning processes, especially if there are some motor skills that need to choose the appropriate method to learn them according to their requirements. Therefore, the research …

The Effect Of Interactive Speed Exercises On Developing Some Skills Women's Futsal, Baneen Mukhif Hamzah, Fatima Abid Malih, Samiha Amara

Modern Sport

The speed of skills has become linked to modern methods of individual and group play, and each of them has begun to serve the other tactically. Through the follow-up of the researchers, they noticed that there is a significant weakness in the speed of performance and slowness in mental preparation, which plays a major role in understanding mental readiness, which is linked to the speed of making decisions during the game, as well as the weakness of the physical speed of the female players, which in turn has an impact on the skill performance of the players of the Iraqi …

Inhaled Medications For Chronic Obstructive Pulmonary Disease Predict Surgical Complications And Survival In Stage I Non-Small Cell Lung Cancer, Steven Tohmasi, Daniel B. Eaton, Brendan T Heiden, Nikki E. Rossetti, Valerio Rasi, Su-Hsin Chang, Yan Yan, Deepika Gopukumar, Mayank R. Patel, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri, Martin W. Schoen

2020-Current year OA Pubs

BACKGROUND: Lung function is routinely assessed prior to surgical resection for non-small cell lung cancer (NSCLC). Further assessment of chronic obstructive pulmonary disease (COPD) using inhaled COPD medications to determine disease severity, a readily available metric of disease burden, may predict postoperative outcomes and overall survival (OS) in lung cancer patients undergoing surgery.

METHODS: We retrospectively evaluated clinical stage I NSCLC patients receiving surgical treatment within the Veterans Health Administration from 2006-2016 to determine the relationship between number and type of inhaled COPD medications (short- and long-acting beta2-agonists, muscarinic antagonists, or corticosteroids prescribed within 1 year before surgery) and postoperative …

Blood Engulfs The Green Earth”: An Ecocritical Reading Of Rasha Fadhlil’S Ishtar In Baghdad And Amy Merrill’S In The Reeds, Maysoon Taher Muhi

Uruk Journal of Human Sciences

In recent times, ecological studies have increasingly been employed to promote environmental awareness across various disciplines and regions worldwide. This paper specifically focuses on the repercussions of war and political violence on Iraq's ecology, which has been greatly impacted by conflict. Two noteworthy plays, Ishtar in Baghdad by Iraqi writer Rasha Fadhlil and In the Reeds by American writer Amy Merrill, shed light on this topic. Both plays, which primarily center on Iraq, underscore that those who fail to appreciate and value human life cannot possibly regard nonhuman entities with reverence. Fadhlil effectively employs elements from Mesopotamian mythology to draw …

Cultural Violence In Saki’S “The Toys Of Peace” And Ahmed Al-Malik’S “The Tank”, Maha Qahtan Sulaiman

Uruk Journal of Human Sciences

Violence cannot be separated from human culture, civilization, and ideology. Ironically, it is society that creates the borders of legal and illegal violence. Therefore, violence is culturally relevant. This paper examines the culture of violence in Saki’s “The Toys of Peace” and Ahmed Al-Malik’s “The Tank.” The two short stories are set in entirely different backgrounds and address violence in relation to children’s and adults’ lives, respectively. The study aims to examine violence in relation to culture and man’s primitive instincts. It also addresses controlling violence through education, promoting peace, and encouraging refined codes of conduct. The paper juxtaposes violence …

Spatial Analysis Of Autism Patients In Baghdad Governorate For The Year 2023, Daniel Mohsen Bashar

Uruk Journal of Human Sciences

The term autism disorder is considered relatively recent and was used at the beginning by psychologists and psychiatrists, including the Swiss psychiatrist Eigen Bleuler in 1911, when he used it to describe people who are isolated from the outside world and withdrawn from social life. As well as studying the demographic characteristics of autistic patients and studying their causes (such as genetic, hereditary, environmental, electronic devices and drugs) and methods of treatment such as treatment (behavioral, educational, family and medication) and the most important problems that suffer from the sufferers and their families. The causes of autism were studied statistically …

Item Generation In The Development Of A Questionnaire For Predicting Multidrug Therapy Compliance In Leprosy, Yulia Siskawati, Sali Rahadi Asih, Aria Kekalih, Sri Linuwih Menaldi, Herqutanto Herqutanto, Kusmarinah Bramono

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Lengthy therapeutic regimens in leprosy are prone to defaults, contributing to more antibiotic-resistant Mycobacterium. Intervening patients’ medical habits midway would be more complicated than understanding their perception of undergoing such regimens in advance. We study the factors considered relevant to leprosy patients’ compliance to construct a novel self-reporting questionnaire that can predict the patients’ adherence before initiating multidrug therapy.

Methods: According to the Delphi methods, we conducted three rounds of interviews with twenty-three respondents from various backgrounds, including dermatologists, government officials, healthcare workers, and patients with leprosy, to infer the associated factors of the included items. Each …

Current Practice In The First Aid Management Of Epistaxis By Nursing Staff Working At The Emergency Departments Of Baghdad Hospitals, Baseem Natheer Abdulhadi

Muthanna Medical Journal

In otolaryngology, epistaxis—nosebleeds—are prevalent and severe. It is estimated that 10% to 60% of people will have at least one serious episode in their lives. This research will question people on how they stop nosebleeds and compare their replies to the medically recommended practice. This cross-sectional study assessed 105 paramedics in Baghdad's Emergency Wards, focusing on their demographics, education, and experience in managing epistaxis (nosebleeds). Key evaluation areas included the patient's position, pressure application on the nose, duration and method of pressure, use of nasal packs, ice application, and decision-making about when to call specialists. Their skills were scored on …

Mir-142: A Master Regulator In Hematological Malignancies And Therapeutic Opportunities, Wilson Huang, Doru Paul, George A Calin, Recep Bayraktar

Faculty, Staff and Student Publications

MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently associated with the onset and progression of human cancers. miR-142, an ultra-conserved miRNA with both active -3p and -5p mature strands and wide-ranging physiological targets, has been the subject of countless studies over the years. Due to its preferential expression in hematopoietic cells, miR-142 has been found to be associated with numerous types of lymphomas and leukemias. This review elucidates the multifaceted role of miR-142 in human physiology, its influence on hematopoiesis and hematopoietic cells, and its intriguing involvement in exosome-mediated miR-142 transport. Moreover, we offer a comprehensive …

Genome-Wide Search Algorithms For Identifying Dynamic Gene Co-Expression Via Bayesian Variable Selection, Wenda Zhang, Zichen Ma, Lianming Wang, Daping Fan, Yen Yi Ho

Faculty Publications

A wealth of gene expression data generated by high-throughput techniques provides exciting opportunities for studying gene-gene interactions systematically. Gene-gene interactions in a biological system are tightly regulated and are often highly dynamic. The interactions can change flexibly under various internal cellular signals or external stimuli. Previous studies have developed statistical methods to examine these dynamic changes in gene-gene interactions. However, due to the massive number of possible gene combinations that need to be considered in a typical genomic dataset, intensive computation is a common challenge for exploring gene-gene interactions. On the other hand, oftentimes only a small proportion of gene …