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2023

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A Comparative Analysis Of The Water Use And Nutritional Value For California Commodities, Helen M. Lee, Giselle A. Pignotti, Kasuen Mauldin, John Gieng Dec 2023

A Comparative Analysis Of The Water Use And Nutritional Value For California Commodities, Helen M. Lee, Giselle A. Pignotti, Kasuen Mauldin, John Gieng

Faculty Research, Scholarly, and Creative Activity

To create a more sustainable food system, this study analyzed the water use and nutritional data for California commodities. The data were separated into quadrants based on median scores, with results that include a list of commodities lower in agricultural water use while being higher in nutritional value. Because the agricultural sector is the dominant water user, there is an opportunity here to influence growers, consumers and policymakers to choose and support the growth of foods that would reduce water consumption while still providing beneficial nutrients. The goal of this paper is to educate the public on this important issue.


The Dna Glycosylase Neil2 Is Protective During Sars-Cov-2 Infection, Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M Sayed, Jason M Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H Sarker, Maki Wakamiya, Victor J Cardenas, Gulshan Sharma, Laura E Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K Hazra Dec 2023

The Dna Glycosylase Neil2 Is Protective During Sars-Cov-2 Infection, Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M Sayed, Jason M Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H Sarker, Maki Wakamiya, Victor J Cardenas, Gulshan Sharma, Laura E Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K Hazra

Faculty, Staff and Students Publications

SARS-CoV-2 infection-induced aggravation of host innate immune response not only causes tissue damage and multiorgan failure in COVID-19 patients but also induces host genome damage and activates DNA damage response pathways. To test whether the compromised DNA repair capacity of individuals modulates the severity of COVID-19 infection, we analyze DNA repair gene expression in publicly available patient datasets and observe a lower level of the DNA glycosylase NEIL2 in the lungs of severely infected COVID-19 patients. This observation of lower NEIL2 levels is further validated in infected patients, hamsters and ACE2 receptor-expressing human A549 (A549-ACE2) cells. Furthermore, delivery of recombinant …


Investigating Trial Design Variability In Trials Of Disease-Modifying Therapies In Parkinson’S Disease: A Scoping Review Protocol, Marie Louise Zeissler, Timothy Boey, Danny Chapman, Gary Rafaloff, Thea Dominey, Karen G. Raphael, Susan Buff, Hari Venkatesh Pai, Emma King, Paul Sharpe, Fintan O’Brien, Camille B. Carroll Dec 2023

Investigating Trial Design Variability In Trials Of Disease-Modifying Therapies In Parkinson’S Disease: A Scoping Review Protocol, Marie Louise Zeissler, Timothy Boey, Danny Chapman, Gary Rafaloff, Thea Dominey, Karen G. Raphael, Susan Buff, Hari Venkatesh Pai, Emma King, Paul Sharpe, Fintan O’Brien, Camille B. Carroll

Peninsula Medical School

Introduction Parkinson’s disease (PD) is a debilitating neurological disorder for which the identification of disease-modifying interventions represents a major unmet need. Diverse trial designs have attempted to mitigate challenges of population heterogeneity, efficacious symptomatic therapy and lack of outcome measures that are objective and sensitive to change in a disease modification setting. It is not clear whether consensus is emerging regarding trial design choices. Here, we report the protocol of a scoping review that will provide a contemporary update on trial design variability for disease-modifying interventions in PD. Methods and analysis The Population, Intervention, Comparator, Outcome and Study design (PICOS) …


A Drosophila Heart Optical Coherence Microscopy Dataset For Automatic Video Segmentation, Matthew Fishman, Abigail Matt, Fei Wang, Elena Gracheva, Jiantao Zhu, Xiangping Ouyang, Andrey Komarov, Yuxuan Wang, Hongwu Liang, Chao Zhou Dec 2023

A Drosophila Heart Optical Coherence Microscopy Dataset For Automatic Video Segmentation, Matthew Fishman, Abigail Matt, Fei Wang, Elena Gracheva, Jiantao Zhu, Xiangping Ouyang, Andrey Komarov, Yuxuan Wang, Hongwu Liang, Chao Zhou

2020-Current year OA Pubs

The heart of the fruit fly, Drosophila melanogaster, is a particularly suitable model for cardiac studies. Optical coherence microscopy (OCM) captures in vivo cross-sectional videos of the beating Drosophila heart for cardiac function quantification. To analyze those large-size multi-frame OCM recordings, human labelling has been employed, leading to low efficiency and poor reproducibility. Here, we introduce a robust and accurate automated Drosophila heart segmentation algorithm, called FlyNet 2.0+, which utilizes a long short-term memory (LSTM) convolutional neural network to leverage time series information in the videos, ensuring consistent, high-quality segmentation. We present a dataset of 213 Drosophila heart videos, equivalent …


Capacity Assessment And Spatial Analysis Of Cervical Cancer Services In The Gambia, Meghan E Mali, Ousman Sanyang, Katherine L Harris, Justin Sorensen, Mustapha Bittaye, Jonathan Nellermoe, Raymond R Price, Edward K Sutherland Dec 2023

Capacity Assessment And Spatial Analysis Of Cervical Cancer Services In The Gambia, Meghan E Mali, Ousman Sanyang, Katherine L Harris, Justin Sorensen, Mustapha Bittaye, Jonathan Nellermoe, Raymond R Price, Edward K Sutherland

Faculty, Staff and Student Publications

Background

Cervical cancer is the most common cancer and the leading cause of cancer-related death in Gambian women. The Gambian Ministry of Health is striving to improve access to screening, diagnostic, and treatment services for cervical cancer, but comprehensive data on currently available services is limited making it challenging to appropriately prioritize the ideal next steps for expanding care. This study aims to describe the current services available for the prevention, screening, and treatment of cervical cancer in The Gambia and provide suggestions for expanding geographic access to care.

Methods

A survey aimed at assessing the availability of key cervical …


Doctor Of Physical Therapy Students’ Experience With Microaggressions In The Clinic: A Call To Action, Jocelin T. Friedman, Todd E. Davenport Dec 2023

Doctor Of Physical Therapy Students’ Experience With Microaggressions In The Clinic: A Call To Action, Jocelin T. Friedman, Todd E. Davenport

Pacific Journal of Health

As Doctor of Physical Therapy (DPT) students fulfill off-campus clinical experience requirements at healthcare institutions, they are mentored by clinical instructors who are employees of said healthcare institutions. Clinical instructors, patients, or other staff members there may commit microaggressions against physical therapy students with varying subject matters, intentions, and effects on the students. Microaggressions are brief verbal humiliations which may or may not be intentional, but nonetheless convey derogatory slights or insults towards a target group. This article explores DPT students’ real-life experiences with microaggressions within the clinical education realm and the challenges a Director of Clinical Education faced in …


An Efficient Non-Parametric Item Selection Method For Polytomous Scoring Cd-Cat, Junjie Li, Huijing Zheng, Chunhua Kang, Pingfei Zeng Dec 2023

An Efficient Non-Parametric Item Selection Method For Polytomous Scoring Cd-Cat, Junjie Li, Huijing Zheng, Chunhua Kang, Pingfei Zeng

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

In educational evaluations at home and abroad, polytomous scoring items are becoming increasingly important. They can provide richer and more valuable information, with unmatched advantages compared to binary (0-1 scoring) items. If used as a tool for teachers to diagnose and assess students in the classroom, CD-CAT (Cognitive Diagnostic Computerized Adaptive Testing) has significant implications for improving teaching effectiveness. However, in classroom teaching situations, it is not feasible to estimate item parameters accurately with a large sample, as in large-scale assessments. In such cases, non-parametric CD-CAT becomes the only viable option. Compared to parametric CD-CAT, non-parametric CD-CAT started later and …


Improving Disability Inclusion Through Professional Development, Carli Spina Dec 2023

Improving Disability Inclusion Through Professional Development, Carli Spina

Urban Library Journal

Building a shared understanding of the importance of disability inclusion and the concrete steps everyone at the library can take towards this goal, is an important first step towards improving services for disabled patrons and the work environment for disabled employees. Offering training on these specific topics can jumpstart this activity at virtually any library. Guided by existing research in the field, this article offers concrete guidance on creating and offering this training at libraries to improve disability inclusion in the community.


Criminal Justice Interventions For Individuals With Mental Health Disabilities: A Systematic Literature Review, Fidelis Azeke, Nassrine Noureddine Dec 2023

Criminal Justice Interventions For Individuals With Mental Health Disabilities: A Systematic Literature Review, Fidelis Azeke, Nassrine Noureddine

Pacific Journal of Health

In the criminal law, with few exceptions, for a finding of guilt, the physical act and the state of mind to commit the offense must be present at the time of the commission of the offense. People with mental disabilities often lack the state of mind required to commit the offense for which they are eventually charged for and or convicted. This paper examines the effectiveness of some past and present criminal justice system interventions that addresses the mental health disabilities of criminal offenders pre-adjudicative proceedings. A systematic review of the literature was used to examine past and present criminal …


Holiday Wassail Concert, Chapman Orchestra, Chapman University Treble Choir, Chapman University Choir, Chapman University Singers Dec 2023

Holiday Wassail Concert, Chapman Orchestra, Chapman University Treble Choir, Chapman University Choir, Chapman University Singers

Printed Performance Programs (PDF Format)

No abstract provided.


Medical School Watercooler Newsletter - December 8, 2023, Lindsey Lyle Dec 2023

Medical School Watercooler Newsletter - December 8, 2023, Lindsey Lyle

Watercooler Newsletter

This is the December 8, 2023 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

  • USA breaks ground on $200 million Whiddon College of Medicine building
  • Rayner awarded grant funding for biotechnology research center
  • Meet a Med Student: Caroline Kinchler
  • USA to break ground on new Whiddon COM building
  • Alumnus and board-certified pediatrician joins pediatrics faculty


Establishment Of Universiti Muhammadiyah Malaysia (Umam) In The Perspective Of Communication For Development Through Education Modernization, Nurlaillah Sari Amallah, Andi Faisal Bakti, Novi Andayani Praptiningsih, Makroen Sanjaya, Tantan Hermansyah Dec 2023

Establishment Of Universiti Muhammadiyah Malaysia (Umam) In The Perspective Of Communication For Development Through Education Modernization, Nurlaillah Sari Amallah, Andi Faisal Bakti, Novi Andayani Praptiningsih, Makroen Sanjaya, Tantan Hermansyah

Informasi

Muhammadiyah is considered a radical conservative movement among the Malaysian Muslim community. The education system in Malaysia is generally exclusive. The majority of Malaysian society is resistant to the Muhammadiyah sect except in certain states. This research used the theory from Servaes and Malikhao, the modernization paradigm that influenced academia from 1945 to 1965 was supported by the transition of sociopolitical technology and culture from advanced societies to traditional societies. Development is explained as economic growth. The main idea in the modernization perspective shows that development is interpreted as first, planned, and overlapping. The results showed ideologically, the principle of …


Nursing Program Facility Groundbreaking, Taylor University Dec 2023

Nursing Program Facility Groundbreaking, Taylor University

Buildings and Grounds of Taylor University

No abstract provided.


Board Of Trustees Meeting Minutes 2023-12-08, Bowling Green State University Dec 2023

Board Of Trustees Meeting Minutes 2023-12-08, Bowling Green State University

Board of Trustees Meeting Minutes

The official meeting minutes of Bowling Green State University's Board of Trustees.


The Medical Action Ontology: A Tool For Annotating And Analyzing Treatments And Clinical Management Of Human Disease., Leigh Carmody, Michael Gargano, Sabrina Toro, Nicole A Vasilevsky, Margaret P Adam, Hannah Blau, Lauren E Chan, David Gomez-Andres, Rita Horvath, Megan L Kraus, Markus S Ladewig, David Lewis-Smith, Hanns Lochmüller, Nicolas A Matentzoglu, Monica C Munoz-Torres, Catharina Schuetz, Berthold Seitz, Morgan N Similuk, Teresa N Sparks, Timmy Strauss, Emilia M Swietlik, Rachel Thompson, Xingmin Aaron Zhang, Christopher J Mungall, Melissa A Haendel, Peter N Robinson Dec 2023

The Medical Action Ontology: A Tool For Annotating And Analyzing Treatments And Clinical Management Of Human Disease., Leigh Carmody, Michael Gargano, Sabrina Toro, Nicole A Vasilevsky, Margaret P Adam, Hannah Blau, Lauren E Chan, David Gomez-Andres, Rita Horvath, Megan L Kraus, Markus S Ladewig, David Lewis-Smith, Hanns Lochmüller, Nicolas A Matentzoglu, Monica C Munoz-Torres, Catharina Schuetz, Berthold Seitz, Morgan N Similuk, Teresa N Sparks, Timmy Strauss, Emilia M Swietlik, Rachel Thompson, Xingmin Aaron Zhang, Christopher J Mungall, Melissa A Haendel, Peter N Robinson

Faculty Research 2023

BACKGROUND: Navigating the clinical literature to determine the optimal clinical management for rare diseases presents significant challenges. We introduce the Medical Action Ontology (MAxO), an ontology specifically designed to organize medical procedures, therapies, and interventions.

METHODS: MAxO incorporates logical structures that link MAxO terms to numerous other ontologies within the OBO Foundry. Term development involves a blend of manual and semi-automated processes. Additionally, we have generated annotations detailing diagnostic modalities for specific phenotypic abnormalities defined by the Human Phenotype Ontology (HPO). We introduce a web application, POET, that facilitates MAxO annotations for specific medical actions for diseases using the Mondo …


The Student Movement Volume 108 Issue 11: A Merry Christmas: From The Sm Staff To You, Grace No, Reagan Westerman, Lauren Kim, Nate Miller, Aiko J. Ayala Rios, Corinna Bevier, Lexie Dunham, Madison Vath, Andrew Francis, Katie Davis, Jonathan Clough, Melissa Moore, Bella Hamann, Abby Shim, Robert Zhang, Rodney Bell Ii, Wambui Karanja, Anna Rybachek, Desmond Hartwell Murray, Shandelle Henson, Amelia Stefanescu Dec 2023

The Student Movement Volume 108 Issue 11: A Merry Christmas: From The Sm Staff To You, Grace No, Reagan Westerman, Lauren Kim, Nate Miller, Aiko J. Ayala Rios, Corinna Bevier, Lexie Dunham, Madison Vath, Andrew Francis, Katie Davis, Jonathan Clough, Melissa Moore, Bella Hamann, Abby Shim, Robert Zhang, Rodney Bell Ii, Wambui Karanja, Anna Rybachek, Desmond Hartwell Murray, Shandelle Henson, Amelia Stefanescu

The Student Movement v. 108 (2023-2024)

HUMANS

Meet the Professors: New Humans Series, Grace No

Psychology Research, Interviewed by Grace No

What's The Deal With Santa Claus?, Reagan Westerman

Student Worker Interview: Sam Namkung, Interviewed by Lauren Kim

ARTS & ENTERTAINMENT

A Flat World for Our Round One, Nate Miller

Art & Music in Andrews' History - Introduction, Aiko J. Ayala Rios

Why Do I Fell Bad for President Snow?: The Ballad of Songbirds and Snakes Review, Corinna Bevier

Have Yourself a Merry Little Hallmark Christmas, Lexie Dunham

It's Beginning to Sound a Lot Like Christmas: A Christmas Playlist, Madison Vath

NEWS

Questions Answered, Questions Avoided: …


Exploring Lgbt Experiences With Family Planning And Reproductive Health, Isabella Lafratta Dec 2023

Exploring Lgbt Experiences With Family Planning And Reproductive Health, Isabella Lafratta

Honors Program Theses and Projects

The purpose of this research is to investigate Lesbian, Gay, Bisexual, Transgender (LGBT) healthcare experiences, specifically in relation to family planning and fertility counseling. Sixteen qualitative, individual interviews were completed with participants recruited from LGBT communities on campus, as well as personal contacts and the snowball effect. Data was analyzed using thematic analysis (Braun & Clarke, 2021), and major themes and subthemes were identified. The first overall theme was Uneasiness and Fear which captures the subtheme: Dysphoria Inducement. The second overarching theme, Lack of Focus on Individualized Needs, had the subthemes of Reproductive Care and Transgender Reproductive Care. This describes …


2023-12-08, Board Of Regents, Murray State University Dec 2023

2023-12-08, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.


Amicus Curiae Brief Of The Navajo Nation, Paul Spruhan Dec 2023

Amicus Curiae Brief Of The Navajo Nation, Paul Spruhan

Faculty Scholarship

The Navajo Nation Labor Commission ("NNLC" or "Commission") invited the Navajo Nation Department of Justice ("DOJ") to file an amicus brief in this matter. As discussed more fully below, the DOJ recommends that the NNLC hold an evidentiary hearing to gather facts necessary to conduct a full jurisdictional analysis under Montana and determine whether the Northern Apache County Special Healthcare District ("NACSHCD") has sovereign immunity. The fact gathering process is necessary given the fact-intensive analysis under both Montana and Arizona's sovereign immunity laws. As the Navajo Supreme Court has instructed, the proper threshold inquiry is whether jurisdiction exists over the …


2023 Fall Commencement Program: Winona State University, Winona State University Dec 2023

2023 Fall Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2023 commencement program. Commencement was on Friday, December 8, 2023.


Sex And Race Differences In Obesity-Related Genetic Susceptibility And Risk Of Cardiometabolic Disease In Older Us Adults, Hairui Yu, Nicole Armstrong, Greg Pavela Dec 2023

Sex And Race Differences In Obesity-Related Genetic Susceptibility And Risk Of Cardiometabolic Disease In Older Us Adults, Hairui Yu, Nicole Armstrong, Greg Pavela

APC Fund

Importance The fat mass and obesity–associated gene (FTO) is associated with obesity phenotypes, but the association is inconsistent across populations. Within-population differences may explain some of the variability observed.

Objective To investigate sex differences in the association between FTO single-nucleotide variants (SNVs) and obesity traits among self-identified non-Hispanic Black and non-Hispanic White US adults, to examine whether the SNVs were associated with cardiometabolic diseases, and to evaluate whether obesity mediated the association between FTO SNVs and cardiometabolic diseases.

Design, Setting, and Participants This cross-sectional study used data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) …


Cultural Determinants Of Help Seeking - Experiences Of African American Mothers And Professional Mental Health Care, Latoya Ashley Dec 2023

Cultural Determinants Of Help Seeking - Experiences Of African American Mothers And Professional Mental Health Care, Latoya Ashley

Walden Dissertations and Doctoral Studies

No abstract provided.


Our Changing Reality: The Metaverse And The Importance Of Privacy Regulations In The United States, Anushkay Raza Dec 2023

Our Changing Reality: The Metaverse And The Importance Of Privacy Regulations In The United States, Anushkay Raza

Global Business Law Review

This Note discusses the legal and pressing digital challenges that arise in connection with the growing use of virtual reality, and more specifically, the metaverse. As this digital realm becomes more integrated into our daily lives, the United States should look towards creating a federal privacy law that protects fundamental individual privacy rights. This Note argues that congress should emulate the European Union's privacy regulations, and further, balances the potential consequences and benefits of adapting European regulations within the United Sates. Finally, this Note provides drafting considerations of future lawyers who will not only be dealing with the rise of …


Strategies For Employee Retention In The U.S. Fast-Food Industry, Veronica Mason Dec 2023

Strategies For Employee Retention In The U.S. Fast-Food Industry, Veronica Mason

Walden Dissertations and Doctoral Studies

No abstract provided.


C-Case 2023: Promoting Excellence In Surgical Education: Canadian Conference For The Advancement Of Surgical Education, Oct. 12-13, 2023, Montréal, Quebec, Jeffrey Sioufi, Brandon Hall, Ryan Antel, Sarah Moussa, Mathushan Subasri, Mustafa Fakih, Nehal Islam, Reggie C. Hamdy, Sonaina Chopra, Karim Damji Dec 2023

C-Case 2023: Promoting Excellence In Surgical Education: Canadian Conference For The Advancement Of Surgical Education, Oct. 12-13, 2023, Montréal, Quebec, Jeffrey Sioufi, Brandon Hall, Ryan Antel, Sarah Moussa, Mathushan Subasri, Mustafa Fakih, Nehal Islam, Reggie C. Hamdy, Sonaina Chopra, Karim Damji

Department of Ophthalmology & Visual Sciences

No abstract provided.


December 8, 2023 Ereporter, University Of Alabama At Birmingham Dec 2023

December 8, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


An Assessment Of Sentencing Disparities By Race In The State Of Arkansas, Viola Schaeffer Dec 2023

An Assessment Of Sentencing Disparities By Race In The State Of Arkansas, Viola Schaeffer

Theses and Dissertations

Past research has found that there are often disparities in sentencing outcomes due to extralegal factors such as race, gender, age, socioeconomic status, education level, and geographic location. The most prominent and widely studied of these factors, however, is race. Specifically, studies have shown that minority offenders (e.g., African Americans) were more likely to receive a lengthier sentence than their White peers. The purpose of this thesis is thus to examine if there is racial bias in sentences levied to violent offenders in Arkansas. This is be done by analyzing sentencing data from the Arkansas Office of the Courts between …


Esg, Public Pensions, And Compelled Speech, Mark R. Kubisch Dec 2023

Esg, Public Pensions, And Compelled Speech, Mark R. Kubisch

Texas A&M Law Review

Investing based on Environmental, Social, and Governance (“ESG”) principles has dramatically increased in recent years. Many institutional investors— including public pension funds funded by mandatory contributions from government employees—now incorporate ESG principles into their investment and engagement strategies even though certain aspects of ESG, such as investing to reduce carbon emissions, are politically controversial. Over this same period, courts have reaffirmed that the First Amendment protects individuals from being compelled to associate with or to subsidize the speech of third parties. Indeed, applying this compelled speech doctrine, the Supreme Court recently overruled a forty-year-old precedent that allowed states to force …


Chronic Kidney Disease Android Application, Paul Le Dec 2023

Chronic Kidney Disease Android Application, Paul Le

Computer Science and Engineering Senior Theses

Chronic kidney disease is increasingly recognized as a leading public health problem over the world that affects more than 10 percent of the population worldwide, where electrolytes and wastes can build up in your system. Kidney failure might not be noticeable until more advanced stages where it may then become fatal if not for artificial filtering or a transplant. As a result, it is important to detect kidney disease early on to prevent it from progressing to kidney failure. The current main test of the disease is a blood test that measures the levels of a waste product called creatine …


Aged And Induced-Premature Ovarian Failure Mouse Models Affect Diestrus Profile And Ovarian Features, Ana Carolina Zucon Bacelar, Nataira Regina Momesso, Felipe Haddad Martim Pederro, Alaíde Gonçalves, Edilson Ervolino, Antonio Hernandes Chaves-Neto, Cláudia Cristina Biguetti, Mariza Akemi Matsumoto Dec 2023

Aged And Induced-Premature Ovarian Failure Mouse Models Affect Diestrus Profile And Ovarian Features, Ana Carolina Zucon Bacelar, Nataira Regina Momesso, Felipe Haddad Martim Pederro, Alaíde Gonçalves, Edilson Ervolino, Antonio Hernandes Chaves-Neto, Cláudia Cristina Biguetti, Mariza Akemi Matsumoto

School of Podiatric Medicine Publications

Sex hormones exert a wide influence on several systems of the human body, especially in women, who undergo intense changes in the trans and postmenopausal periods. Different experimental models are used to mimic these conditions; however, the impact on hormonal profile may be different. This study aimed to analyze and compare vaginal cytology of different post-estropausal mice models, along with their microscopical ovarian features. Forty-six C57BL/6J female mice with the ages of 4, 6 and 18 months at the beginning of the experiment, weighing about 25–28 grams, constituted five groups: NC–(negative control) animals with no treatment, OVX-SHAM—sham ovariectomized, OVX–ovariectomized, VCD–medicated …